CN114948335B

CN114948335B - Embolism plugging device

Info

Publication number: CN114948335B
Application number: CN202210902139.XA
Authority: CN
Inventors: 董永贺; 刘颖; 朱明哲
Original assignee: Beijing Huamai Taike Medical Instrument Co ltd
Current assignee: Beijing Huamai Taike Medical Instrument Co ltd
Priority date: 2022-07-29
Filing date: 2022-07-29
Publication date: 2022-09-27
Anticipated expiration: 2042-07-29
Also published as: CN114948335A

Abstract

The invention provides a plug plugging device, which relates to the field of medical instruments and comprises a film, a supporting wire and a tightening wire; the film comprises a strip-shaped sheet main body; the supporting wires are connected with the sheet-shaped main body; the tightening wire penetrates through the sheet main body, the far end of the tightening wire is fixed at the far end of the sheet main body, and the near end of the tightening wire is a free end at the near end of the sheet main body or penetrates out of the sheet main body and is reversely folded to the other surface of the sheet main body and then is fixedly connected with the sheet main body; when the proximal end of the sheet-shaped main body is blocked, the tightening wire is pulled towards the proximal direction or the proximal end of the sheet-shaped main body is pushed towards the distal direction relative to the tightening wire, and the sheet-shaped main body is stacked along the tightening wire. The invention solves the problems of large spring coil consumption, complex operation, large burden of patients and poor embolism plugging effect when the spring coil is used for plugging the aneurysm in the prior art, is convenient to implement when plugging a aneurysm cavity or a false cavity, can reduce the postoperative burden of the patients, and simultaneously ensures and/or improves the embolism plugging effect.

Description

Embolism plugging device

Technical Field

The invention relates to the technical field of medical instruments, in particular to a plug plugging device.

Background

The aorta consists of three layers, called intima, media and adventitia, respectively; aortic Dissection (AD) refers to the state in which blood enters the Aortic media from the intimal laceration (laceration) of the Aortic wall, and the blood in the Aortic lumen is driven by the pulse pressure to separate the media and expand along the major axis of the aorta, so as to separate the Aortic wall into true and false lumens, where the true lumen refers to the original lumen of normal blood flow, and the false lumen refers to the newly lacerated diseased lumen. The aneurysm refers to the aneurysm which expands like a tumor, usually the diameter of the aneurysm is defined as the aneurysm, the risk of the rupture of the tumor body increases exponentially along with the increase of the tumor body, once the rupture of the tumor body, a large amount of blood is infused into the abdominal cavity, and the circulating blood volume of a patient is insufficient, so that the patient suffers from ischemic shock and even dies.

For aortic dissection and Aneurysm, the current medicines cannot cure, and the treatment method mainly comprises traditional open surgery and endoluminal Repair (EVAR). Due to the reasons of large trauma, long recovery period, high mortality and the like of the open type operation, the patients often prefer the EVAR operation with small trauma and low mortality to treat the abdominal aortic aneurysm on the premise of meeting the EVAR treatment.

At present, when an EVAR operation is performed, after a covered stent is implanted, there is a high risk of type I internal leakage, that is, internal leakage occurs between the covered stent and the inner circumferential surface of a breach of a false cavity, or between the covered stent and the inner circumferential surface of the distal end or the proximal end of a tumor cavity, and for the type I internal leakage, plugging is mainly performed in an embolism manner at present. For the aortic dissection, an embolism blocking device is implanted into a dissection false cavity to promote the embolization of the false cavity, or a broken opening (a broken opening at the near end of the dissection) in the aortic wall is blocked to prevent the blood backflow of the broken opening at the near end of the false cavity; for aneurysm, at present, the spring coil is mainly used for plugging, which is well implemented for small vessel aneurysms such as intracranial arteries and peripheral arteries, but for plugging of aneurysm endoleaks, a plurality of spring coils or even dozens of spring coils are often used for plugging, and the problems of large spring coil consumption, complex operation, large burden on patients and poor embolism plugging effect exist.

Disclosure of Invention

The invention aims to provide an embolism blocking device which is applied to aneurysm blocking and aortic dissection false cavity blocking, is convenient to implement when a aneurysm cavity or a false cavity is blocked, can reduce postoperative burden of a patient, and simultaneously has the function of ensuring and/or improving embolism blocking effect.

In order to achieve the above purpose, the embodiment of the invention adopts the following technical scheme:

the embodiment of the invention provides a plug plugging device, which comprises a film, a supporting wire and a tightening wire, wherein the film is covered on the supporting wire;

the covering film comprises a strip-shaped sheet main body;

the supporting wires are connected to the sheet-shaped main body along the length direction of the sheet-shaped main body;

taking one end of the flaky main body in the length direction as the proximal end of the plug plugging device, and taking the other end of the flaky main body in the length direction as the distal end of the plug plugging device: the far end of the tightening wire is fixedly connected with the far end of the sheet-shaped main body; the tightening wire is inserted into the sheet-shaped main body along the length direction of the sheet-shaped main body in a mode of repeatedly penetrating through the sheet-shaped main body; at the proximal end of the sheet-like body: the proximal end of the tightening wire penetrates out of the sheet-shaped main body from one surface of the sheet-shaped main body and is folded back to the other surface of the sheet-shaped main body and then fixedly connected to the sheet-shaped main body, or the proximal end of the tightening wire penetrates out of one surface of the sheet-shaped main body to form a free end;

in a case where the proximal end of the sheet-like body is blocked, the sheet-like body can be stacked along the tightening wire from the proximal end of the tightening wire toward the distal end of the tightening wire by pulling the tightening wire in the proximal direction or pushing the proximal end of the sheet-like body in the distal direction with respect to the tightening wire.

During operation, the conveyor is used for conveying and implanting the embolism plugging device provided by the embodiment into a tumor cavity or a false cavity, occupation in the thickness direction is increased, and then rapid plugging is performed on the blood vessel tumor cavity or the interlayer false cavity, especially for plugging an aortic tumor cavity, compared with the plugging of tens of spring rings in the prior art, the plugging effect can be achieved by only stacking sheet main bodies by using one embolism plugging device in the embodiment, the whole plugging process is simple and convenient, the operation efficiency is high, and compared with tens of spring rings, the burden of a patient can be reduced; in addition, this embolism plugging device's structural feature, the above-mentioned mode of implanting of cooperation, the support wire has the trend that makes the tectorial membrane have the length direction and expand, the tightening wire can be adjusted tectorial membrane maximum length, the tightening wire draws tighter, the slice main part is shorter thick, both mutually support of support wire and tightening wire can make the tectorial membrane reach the form controllable, therefore, can tighten up the taut degree of silk according to the form control of the target blood vessel of difference or false chamber, with the degree of piling up of control slice main part, so that this embolism plugging device adapts to tumor chamber or false chamber form better, compare in mixed and disorderly spring coil, it is littleer to the stimulation of vascular wall.

In summary, the embodiment of the invention at least relieves the problems of large spring coil consumption, complicated operation, large burden of patients and poor embolism blocking effect when the spring coil is adopted for aneurysm blocking in the prior art, and in addition, the invention can also be applied to blocking of aortic dissection false lumens.

In an optional implementation manner of this embodiment, the plug occlusion device further includes a stopper, and the stopper is slidably connected to a portion of the tightening wire located on the proximal end side of the sheet-like main body, and is used for blocking the proximal end of the sheet-like main body.

Further optionally, the limiting member is provided with a through hole or a slit, the tightening wire penetrates through the through hole or the slit and is in contact with the through hole or the slit, and a friction force between the tightening wire and the through hole or the slit is greater than a supporting force of the supporting wire acting on the sheet-shaped main body.

Still further optionally, the retaining member is a spring or a threaded pipe with internal threads or a pipe piece with side slits or a sheet material with slits.

Optionally, the tightening wire is further provided with a one-way limiting structure, and the one-way limiting structure is configured to: and constraining the limiting piece so that the limiting piece can only slide along the tightening wire in one direction from the near end to the far end.

Optionally, the outer circumferential surface of the one-way limiting structure is in a conical shape or a frustum shape, the radial sectional area of the conical shape or the frustum shape is gradually reduced, and the distal end of the tightening wire faces the proximal end of the tightening wire; and/or the limiting part comprises a limiting part main body, a through hole is arranged in the middle of the limiting part main body, the through hole and the periphery of the inner avoiding surface of the whole limiting part are in a conical shape or a frustum shape, the radial sectional area of the conical shape or the frustum shape is gradually reduced from the far end of the tightening wire to the near end of the tightening wire; and/or the near end of the limiting piece is provided with a limiting claw. Wherein "and/or" means "and/or" preceding structure is provided simultaneously or alternatively to "and/or" following structure.

In an optional implementation manner of this embodiment, the supporting wires are in a shape of a spiral along the length direction, and the supporting wires are inserted and connected to the side portions of one or both sides of the sheet-shaped main body along the length direction of the sheet-shaped main body.

In an optional implementation manner of this embodiment, one or both sides of the sheet-shaped main body in the length direction are further provided with cilia; and/or, the two sides of the sheet main body in the length direction are respectively a first side and a second side; the support wires are wavy to vibrate between the first side edge and the second side edge.

In an optional implementation manner of this embodiment, the plurality of insertion holes through which the tightening wire passes on the sheet-shaped main body are arranged at intervals in a non-linear manner in both the length direction and the width direction of the sheet-shaped main body; and/or the sheet main body is solid or has a hollow structure; and/or, the sheet-shaped main body is made of degradable materials. Wherein "and/or" means "and/or" preceding structure is provided simultaneously or alternatively to "and/or" following structure.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.

FIG. 1 is a schematic diagram of the overall structure of an alternative embodiment of an embolic occlusion device as provided by an embodiment of the present invention;

FIG. 2 is a schematic view of the stopper of the embolic occlusion device of FIG. 1;

FIG. 3 is a schematic overall structure diagram of another alternative embodiment of the embolic occlusion device provided in an embodiment of the present invention;

FIG. 4 is a schematic view of the stopper of the embolic occlusion device of FIG. 3;

FIG. 5 is a schematic view of the assembly of the embolic occlusion device shown in FIG. 1 with a delivery device;

FIG. 6 is an enlarged view of a portion A of FIG. 5;

FIG. 7 is a schematic view of another connection between the puller wire and the puller wire of the delivery device shown in FIG. 1;

fig. 8 is a schematic view of a pushing manner of pushing the distal end of the transporter to the body of the patient in the implantation method of the embolic occlusion device according to the embodiment of the present invention.

Icon: 100-embolic occlusion devices; 1-covering a film; 11-a sheet-like body; 12-cilia; 2-supporting wires; 3-tightening the filaments; 31-one-way limiting structure; 4-a limiting member; 41-a limiter body; 42-a limiting claw; 51-a pull line; 52-an outer tube; 520-a fast switching port; 53-ejector; 6-guide wire.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.

Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.

In the description of the present invention, it should be noted that the terms "distal end", "proximal end", "front end", "rear end", "inner" and "outer" are used for indicating the orientation or positional relationship based on the orientation or positional relationship shown in the drawings or the orientation or positional relationship which the product of the present invention is used for, and are only for convenience of describing the present invention and simplifying the description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and the like are used merely to distinguish one description from another, and are not to be construed as indicating or implying relative importance.

In particular, in the present invention, the term "distal end" refers to the end of the medical instrument that is closer to the patient during the operation (also the front end of the medical instrument), and "proximal end" refers to the end of the medical instrument that is closer to the operator during the operation (also the rear end of the medical instrument).

Furthermore, the terms "horizontal", "vertical" and the like do not imply that the components are required to be absolutely horizontal or pendant, but rather may be slightly inclined. For example, "horizontal" merely means that the direction is more horizontal than "vertical" and does not mean that the structure must be perfectly horizontal, but may be slightly inclined.

In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "disposed," "mounted," and "connected" are to be construed broadly, e.g., as meaning fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.

Some embodiments of the invention are described in detail below with reference to the accompanying drawings. The embodiments described below and the features of the embodiments can be combined with each other without conflict.

A first aspect of the present embodiment provides an embolic occlusion device, which, with reference to fig. 1 to 4, comprises a covering membrane 1, a support wire 2 and a tightening wire 3.

Specifically, the coating film 1 includes an elongated sheet-like body 11; the supporting wires 2 are connected to the sheet-shaped main body 11 along the length direction of the sheet-shaped main body 11; one end in the length direction of the sheet-shaped main body 11 is taken as the proximal end of the plug plugging device, and the other end in the length direction of the sheet-shaped main body 11 is taken as the distal end of the plug plugging device: the far end of the tightening wire 3 is fixedly connected with the far end of the sheet-shaped main body 11; the tightening wire 3 is inserted into the sheet main body 11 along the length direction of the sheet main body 11 in a manner of repeatedly penetrating through the sheet main body 11; the proximal end of the tensioning wire 3 has at least two morphologies at the proximal end of the sheet-like body 11: first, as shown in fig. 7, the proximal end of the wire 3 is passed out of one surface of the sheet-like body 11 at the proximal end of the sheet-like body 11 and folded back toward the other surface of the sheet-like body 11, and then fixedly attached to the sheet-like body 11, or, second, as shown in fig. 1 and 6, the proximal end of the wire 3 is passed out of one surface of the sheet-like body 11 at the proximal end of the sheet-like body 11 to be formed as a free end.

In the case where the proximal end of the sheet-like body 11 is blocked, pulling the tightening wire 3 in the proximal direction or pushing the proximal end of the sheet-like body 11 in the distal direction with respect to the tightening wire 3, the sheet-like body 11 can be stacked along the tightening wire 3 from the proximal end of the tightening wire 3 to the distal end of the tightening wire 3.

Correspondingly, a second aspect of the present embodiment provides an implantation method of the embolic occlusion device, which is used for implanting the embolic occlusion device 100 provided by the first aspect into a patient through a transporter; referring to fig. 5 to 8, the conveyor includes a pulling wire 51, an outer tube 52, and an ejector 53 disposed inside the outer tube 52 and capable of axially sliding with respect to the outer tube 52, where the ejector 53 may be, but is not limited to, a core tube or a core wire; further, the pulling wire 51 passes through the outer tube 52.

The implantation method comprises a loading step, a pushing step and an implantation step, and specifically comprises the following steps:

the loading step includes: for implanting into a patient by means of a transporter an embolic occlusion device as provided in any of the preceding first aspects.

Wherein, the delivery device at least comprises a pulling wire 51, an outer tube 52, and an ejector 53 disposed inside the outer tube 52 and capable of sliding axially relative to the outer tube 52, the ejector 53 can be, but not limited to, a core tube or a core wire, the pulling wire 51 passes through the outer tube 52, more specifically, the pulling wire 51 can pass through a gap between the outer tube 52 and the ejector 53, or pass through a lumen of the ejector 53 when the ejector 53 is a core tube or other structure having a lumen.

The implantation method at least comprises a loading step, a pushing step, an implantation step and a post-release step; specifically, the method comprises the following steps:

the loading step includes: loading the plug occluding device inside the outer tube 52 by compressing it in the width direction in a manner of folding stack or curling, etc., and making the distal end of the tightening wire 3 close to the distal end of the outer tube 52 and the proximal end of the tightening wire 3 close to the proximal end of the outer tube 52; the proximal end of the tightening wire 3 is movably connected with a pulling wire 51; the distal end of the ejector 53 is located on the proximal end side of the sheet-like body 11, wherein the movable connection means for movably connecting the proximal end of the tightening wire 3 to the pulling wire 51 includes at least two types, the first type, as shown in fig. 5 and 6, is a snap connection of the tightening wire 3 to the pulling wire 51, or the second type, as shown in fig. 7, in the case where the proximal end of the tightening wire 3 is fixedly connected to the sheet-like body 11 after passing through the sheet-like body 11 from one surface of the sheet-like body 11 at the proximal end of the sheet-like body 11 and being folded back toward the other surface of the sheet-like body 11, one end of the tightening wire 3 is passed through the delivery tube from the proximal end of the delivery device and passed through the distal end of the delivery tube, further passed through the proximal end of the tightening wire 3 inside the distal end of the delivery tube after being folded back into a loop formed at the reverse proximal end of the sheet-like body 11, further passed through the proximal end of the delivery tube, and the suspension loop formed at the proximal end of the sheet-like body 11 at the proximal end of the tightening wire 3 is pulled by pulling both ends of the tightening wire 3, thereby pulling the tightening wire 3.

The pushing step comprises: the transporter is operated to advance the distal end of the outer tube 52 loaded with the embolic occlusion device to the site of the lesion in the patient. The specific pushing manner includes, as shown in fig. 8, providing a rapid exchange port 520 at the distal end of the outer tube 52, delivering the guide wire 6 into the target blood vessel, inserting the proximal end of the guide wire 6 into the outer tube 52 from the distal end of the outer tube 52 and penetrating out of the rapid exchange port 520, and pushing the entire delivery device forward under the guidance of the guide wire 6 until the distal end of the outer tube 52 loaded with the embolic occlusion device 100 is pushed to the lesion site of the patient; or, the adopted conveyor comprises an outer tube 52, a core tube and an intermediate tube arranged between the outer tube 52 and the core tube, the distal end of the intermediate tube is abutted against the proximal end of the embolism occlusion device 100 compressed in the outer tube 52, the guide wire penetrates out from the middle part of the core tube, and the conveyor is integrally pushed forward under the guidance of the guide wire until the distal end of the outer tube 52 loaded with the embolism occlusion device is pushed to the lesion position of the patient; alternatively, a guiding sheath may be pushed into the blood vessel under the guidance of the guide wire, and then the guide wire is withdrawn, and the transporter is pushed to the target blood vessel (the lesion site of the patient) inside the guiding sheath.

The implanting step includes: pushing the ejector 53 distally relative to the outer tube 52, or withdrawing the outer tube 52 relative to the ejector 53, such that the ejector 53 exposes the embolic occlusion device at the distal end of the outer tube 52;

the implanting step further comprises: pulling the pulling wire 51 in a proximal direction relative to the outer tube 52 and the ejector 53, so that the ejector 53 abuts against the proximal end of the sheet-shaped body 11, and continuously pulling the pulling wire 51 in the proximal direction relative to the outer tube 52 and the ejector 53, so that the pulling wire 51 drives the tightening wire 3 to move in the proximal direction relative to the sheet-shaped body 11, and further, the sheet-shaped body 11 is stacked along the tightening wire 3 from the proximal end of the tightening wire 3 to the distal end of the tightening wire 3; alternatively, the ejector 53 is pushed in the distal direction with respect to the pulling wire 51 and the outer tube 52, so that the ejector 53 presses the proximal end of the sheet-like body 11 in the distal direction, and the sheet-like bodies 11 are stacked along the tightening wire 3 from the proximal end of the tightening wire 3 to the distal end of the tightening wire 3.

The post-release step comprises: the connection between the pull wire 51 and the tightening wire 3 is released, the conveyer is withdrawn out of the patient body, and when the proximal end of the tightening wire 3 is movably connected to the pull wire 51 in the connection mode shown in fig. 7, the connection can be released when the pull wire 51 needs to be withdrawn.

During operation, the implantation steps can be utilized to convey and implant the embolism plugging device provided by the embodiment into a tumor cavity or a false cavity, so that the occupation in the thickness direction is increased, and then the blood vessel tumor cavity or the interlayer false cavity is quickly plugged, especially for plugging an aortic tumor cavity, compared with the plugging of dozens of spring rings in the prior art, the plugging effect can be achieved by only adopting one embolism plugging device to stack the sheet main bodies 11, the whole plugging process is simple and convenient, the operation efficiency is high, and compared with dozens of spring rings, the burden of a patient can be reduced; in addition, this embolism plugging device's structural feature, the cooperation above-mentioned mode of implanting, support wire 2 has the trend that makes tectorial membrane 1 have length direction and expand, the maximum length of tectorial membrane 1 can be adjusted to the tightening wire 3, the tighter the tightening wire 3 is drawn, the more short and thick slice main part 11, support wire 2 and tightening wire 3 both cooperate each other and can make tectorial membrane 1 reach the form controllable, therefore, can control the taut degree of tightening wire 3 according to the form of different target blood vessels or false cavitys to the pile up degree of control slice main part 11, so that this embolism plugging device adapts to tumor cavity or false cavity form better, compare in mixed and disorderly spring coil, it is littleer to the stimulation of vascular wall.

The embolic occlusion device provided in this embodiment is further described below:

in this embodiment, referring to fig. 1 to 6, the plug occlusion device further includes a stopper 4, and the stopper 4 is slidably connected to a portion of the tightening wire 3 located at the proximal end side of the sheet-like main body 11, and is used for stopping the proximal end of the sheet-like main body 11. Optionally, the position-limiting member 4 is provided with a through hole or a slit, the tightening wire 3 passes through the through hole or the slit, and the tightening wire 3 and the through hole or the slit are in contact with each other to generate a friction force, and the friction force between the tightening wire 3 and the through hole or the slit is greater than the supporting force of the supporting wire 2 acting on the sheet-shaped main body 11. Specifically, the stopper 4 may be, but not limited to, a spring or a threaded pipe with an internal thread or a pipe piece with a side slit or a sheet material with a slit.

The diameter of the stopper 4 is set to be larger than the inner diameter of the ejector 53 and smaller than the inner diameter of the outer tube 52, and in the implanting step, the pulling wire 51 can be pulled in the proximal direction relative to the outer tube 52 and the ejector 53, so that the ejector 53 abuts against the stopper 4, the pulling wire 51 is continuously pulled in the proximal direction relative to the outer tube 52 and the ejector 53, so that the pulling wire 51 drives the tightening wire 3 to move in the proximal direction relative to the stopper 4, and in the process, the proximal end of the sheet-like body 11 contacts the distal end of the stopper 4, the stopper 4 abuts against the proximal end of the sheet-like body 11 to stop the sheet-like body 11 from moving further in the proximal direction, and at this time, the ejector 53 abuts against the proximal end of the sheet-like main body 11 by virtue of the limiting member 4, and the pull wire 51 is continuously pulled in the proximal direction, so that the sheet-like main bodies 11 are stacked along the tightening wire 3 from the proximal end of the tightening wire 3 to the distal end of the tightening wire 3 under the blocking action of the limiting member 4; alternatively, in the implanting step, the ejector 53 is pushed in the distal direction relative to the pull wire 51 and the outer tube 52, so that the ejector 53 presses the stopper 4 in the distal direction, and the stopper 4 slides in the distal direction along the tightening wire 3, thereby pressing the sheet-like body 11, so that the sheet-like body 11 is stacked along the tightening wire 3 from the proximal end of the tightening wire 3 to the distal end of the tightening wire 3. Of course, in other alternative but less preferred embodiments of the present embodiment, the stopper 4 may not be provided, but the ejection member 53 may be used to block the sheet-like body 11 completely during the implantation step, or the stopper 4 may be provided as well, but the stopper 4 is not directly connected to the tightening wire 3, but is connected to the distal end of the ejection member 53.

In this embodiment, in the above optional implementation of the limiting member 4, preferably, as shown in fig. 1 to 4, the tightening wire 3 is further provided with a one-way limiting structure 31, and the one-way limiting structure 31 is integrally or fixedly or interference-fittingly sleeved on the tightening wire 3 and configured to: the limiting member 4 is constrained so that the limiting member 4 can only slide unidirectionally along the tightening wire 3 from the proximal end toward the distal end, and after the limiting member 4 slides to the distal end side of the unidirectional limiting structure 31 along the tightening wire 3 toward the distal end, the unidirectional limiting structure 31 blocks the proximal end side of the limiting member 4. Optionally, the one-way limiting structure 31 includes at least one limiting ball, a circumferential surface of the limiting ball is in a conical shape or a frustum shape with a gradually decreasing radial sectional area from the distal end of the tightening wire 3 to the proximal end of the tightening wire 3, the one-way limiting structures 31 are preferably provided in plurality in number, and the plurality of one-way limiting structures 31 are provided at intervals along the length direction of the tightening wire 3, and are used for limiting the compressed state of the sheet-shaped main body 11 by matching with the limiting member 4 when the sheet-shaped main body 11 is stacked along the tightening wire 3.

In the preferred embodiment, the retaining member 4 is slid along the tightening wire 3 in the distal direction to the distal side of the one-way retaining structure 31, the limiting member 4 may be an elastic deformation structure, the limiting member 4 is elastically deformed and then restored to be deformed, or, the one-way limiting structure 31 is an elastic deformation structure, the one-way limiting structure 31 is firstly elastically deformed and then restores to be deformed, alternatively, as shown in fig. 2, the position-limiting member 4 comprises a position-limiting member main body 41, and a through hole is provided in the middle of the position-limiting member main body 41, preferably, as shown in fig. 1 and 6, the inner wall of the through hole of the limiting member 4 is in a tapered shape or a frustum shape with a gradually decreasing radial sectional area from the distal end of the tightening wire 3 to the proximal end of the tightening wire 3, and when the limiting member 4 slides to the distal end side of the one-way limiting structure 31 along the tightening wire 3 in the distal direction, the one-way limiting structure 31 is elastically deformed and then returns to the deformation. Preferably, but not limited to, the limiting member body 41 is provided with at least three limiting claws 42 at the distal end, the gap between adjacent limiting claws 42 provides a deformation space for the elastic deformation of the one-way limiting structure 31, after the limiting member 4 slides to the distal end side of the one-way limiting structure 31 along the tightening wire 3 in the distal direction, the limiting claws 42 are limited at the distal end side of the one-way limiting structure 31 in one direction, in other structures of the limiting member 4, the limiting claws 42 may not be provided, but slits may be provided on the peripheral wall of the limiting member 4 to provide a deformation space for the elastic deformation of the one-way limiting structure 31.

In some optional embodiments of this embodiment, as shown in fig. 1, the supporting wires 2 are in a shape of a spiral along the length direction, and the supporting wires 2 are inserted and connected to the edge portions of one side or two sides (preferably two sides) of the sheet-shaped body 11 along the length direction of the sheet-shaped body 11.

In some optional embodiments of this embodiment, as shown in fig. 3, cilia 12 are further provided on one side or both sides (preferably both sides) of the sheet-like body 11 in the length direction, so that the sheet-like body 11 is overall feather-like, when the sheet-like body 11 is stacked, the cilia 12 are used to reduce the stimulation to the blood vessel wall, and the adaptability of the sheet-like body 11 to the tumor cavity or the false cavity is enhanced, thereby achieving the functional effect of easily filling irregular gaps of the tumor cavity or the false interlayer cavity.

In some alternative embodiments of the present embodiment, as shown in fig. 3, the two sides of the sheet-like main body 11 in the length direction are respectively a first side and a second side; the support wire 2 is the wavy of vibration between first side and second side to, can make flaky main part 11 not only can expand at length direction under natural state, still can expand at width direction, and then be favorable to increasing after this embolism plugging device releases and fill the occupation space, reinforcing shutoff effect.

In some optional embodiments of the present embodiment, the insertion holes on the sheet-shaped main body 11 for the tightening wires 3 to pass through are arranged at non-linear intervals in both the length direction and the width direction of the sheet-shaped main body 11, and in this irregular arrangement, the irregularity of the sheet-shaped main body 11 during stacking can be increased, so as to further increase the adaptability to the tumor cavities and the false cavities with different shapes.

In some optional embodiments of the present embodiment, the sheet-like body 11 is solid or has a hollow structure similar to a bath flower or a filter screen.

In some alternative embodiments of the present embodiment, the sheet-like body 11 is made of PLA (polylactic acid) or other degradable material to increase the adaptability to the human body.

Finally, it should be noted that: the embodiments in the present description are all described in a progressive manner, each embodiment focuses on the differences from the other embodiments, and the same and similar parts among the embodiments can be referred to each other; the above embodiments in the present specification are only used for illustrating the technical solutions of the present invention, and not for limiting the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. The utility model provides a plug plugging device which characterized in that: comprises a coating (1), a supporting wire (2) and a tightening wire (3);

the film (1) comprises a strip-shaped sheet-shaped main body (11);

the supporting wires (2) are connected to the sheet-shaped main body (11) along the length direction of the sheet-shaped main body (11);

taking one end of the sheet-shaped main body (11) in the length direction as the proximal end of the plug plugging device, and the other end of the sheet-shaped main body (11) in the length direction as the distal end of the plug plugging device: the far end of the tightening wire (3) is fixedly connected with the far end of the sheet-shaped main body (11); the tightening wire (3) is inserted into the sheet-shaped main body (11) along the length direction of the sheet-shaped main body (11) in a mode of repeatedly penetrating through the sheet-shaped main body (11); at the proximal end of the sheet-like body (11): the proximal end of the tightening wire (3) penetrates out of the sheet-shaped main body (11) from one surface of the sheet-shaped main body (11) and is folded back to the other surface of the sheet-shaped main body (11) to be fixedly connected to the sheet-shaped main body (11), or the proximal end of the tightening wire (3) penetrates out of one surface of the sheet-shaped main body (11) to form a free end;

in the case where the proximal end of the sheet-like body (11) is blocked, the sheet-like body (11) can be stacked along the tightening wire (3) from the proximal end of the tightening wire (3) to the distal end direction of the tightening wire (3) by pulling the tightening wire (3) in the proximal end direction or pushing the proximal end of the sheet-like body (11) in the distal end direction with respect to the tightening wire (3).

2. The embolic occlusion device of claim 1, wherein: the embolism plugging device further comprises a limiting part (4), wherein the limiting part (4) is connected to the part, located on the proximal end side of the sheet-shaped main body (11), of the tightening wire (3) in a sliding mode and used for blocking the proximal end of the sheet-shaped main body (11).

3. The embolic occlusion device of claim 2, wherein: the limiting part (4) is provided with a through hole or a gap, the tightening wire (3) penetrates through the through hole or the gap, the tightening wire (3) is in contact with the through hole or the gap, and the friction force between the tightening wire (3) and the through hole or the gap is larger than the supporting force of the supporting wire (2) acting on the sheet-shaped main body (11).

4. The embolic occlusion device of claim 3, wherein: the limiting piece (4) is a spring or a threaded pipe with internal threads or a pipe fitting with a side seam or a sheet material with a seam.

5. The embolic occlusion device of any of claims 2-4, wherein: still be equipped with one-way limit structure (31) on tightening wire (3), one-way limit structure (31) configure into: and constraining the limiting part (4) so that the limiting part (4) can only slide along the tightening wire (3) from the near end to the far end in one direction.

6. The embolic occlusion device of claim 5, wherein:

the outer peripheral surface of the one-way limiting structure (31) is in a conical or frustum shape that the distal end of the tightening wire (3) faces the proximal end of the tightening wire (3) and the radial sectional area is gradually reduced;

and/or the limiting part (4) comprises a limiting part main body (41), a through hole is formed in the middle of the limiting part main body (41), the inner avoiding surface of the through hole is in a conical shape or a frustum shape, the radial sectional area of the conical shape or the frustum shape is gradually reduced from the far end of the tightening wire (3) to the near end of the tightening wire (3);

and/or a limiting claw (42) is arranged at the near end of the limiting piece (4).

7. The embolic occlusion device of claim 1, wherein: the supporting wires (2) are in a spiral shape along the length direction, and the supporting wires (2) are inserted and connected to the edge parts of one side or two sides of the sheet main body (11) along the length direction of the sheet main body (11).

8. The embolic occlusion device of claim 1, wherein: one side or two sides of the sheet-shaped main body (11) in the length direction are also provided with cilia (12); and/or, the two sides of the sheet main body (11) in the length direction are respectively a first side and a second side; the supporting wires (2) are in a wavy shape which vibrates between the first side edge and the second side edge.

9. The embolic occlusion device of claim 1, wherein:

the sheet-shaped main body (11) is provided with a plurality of insertion holes for the tightening wires (3) to pass through, and the insertion holes are arranged at intervals in a non-linear mode in the length direction and the width direction of the sheet-shaped main body (11);

and/or the sheet main body (11) is solid or has a hollow structure;

and/or the sheet-shaped body (11) is made of degradable materials.