CN114917067A - Nickel-titanium alloy stent in human body lumen - Google Patents

Nickel-titanium alloy stent in human body lumen Download PDF

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Publication number
CN114917067A
CN114917067A CN202210558825.XA CN202210558825A CN114917067A CN 114917067 A CN114917067 A CN 114917067A CN 202210558825 A CN202210558825 A CN 202210558825A CN 114917067 A CN114917067 A CN 114917067A
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stent
support
section
nickel
titanium alloy
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CN202210558825.XA
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Chinese (zh)
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胡闯
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Individual
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

The invention discloses a nickel-titanium alloy stent in a human body lumen, relating to the technical field of medical equipment; the support comprises a support body, the support body is formed by a plurality of sections of support frameworks distributed in a shape like a Chinese character 'ji', framework connecting lines are arranged between every two sections of support frameworks, a telescopic net structure is formed between the support frameworks and the framework connecting lines, the support frameworks and the framework connecting lines are integrally formed by nickel-titanium alloy 3D printing, and annular ports are arranged at two ends of the support body. After the stent is expanded, the port part of the stent is smooth and stable, the adhesion and the friction between the stent and the wall of a blood vessel cavity are increased, meanwhile, after the annular port is expanded, the port part forms effective support, the annular port cannot shrink due to the peristalsis of the wall of the blood vessel cavity, the stability of the fixation of the stent is improved, meanwhile, the cross sections of the stent framework, the annular port and the framework connecting line which form the stent are all of an oval structure, and the contact area of the outer side of the stent framework and the wall of the blood vessel cavity is increased.

Description

Nickel-titanium alloy stent in human body lumen
Technical Field
The invention relates to the technical field of medical equipment, in particular to a nickel-titanium alloy stent in a human body lumen.
Background
The lumen stent expands the lumen by tearing the intima and media of the blood vessel during balloon dilatation, and the expanded diameter is maintained by blood pressure. The damaged intima and media of the blood vessel are deposited with platelets and fibers, and the endothelium of the blood vessel is covered and repaired. Intraluminal stenting is a procedure for the treatment of luminal obstruction or stenotic lesions. Usually, the lumen is first blocked, punctured, dilated and the stent is placed in the lumen. It is divided into two categories, vascular and non-vascular. The former is mainly used for treating obstructive vascular disease, can improve curative effect and reduce restenosis; the latter is mainly used for treating tumor digestive tract or biliary tract luminal stenosis, and can solve obstruction.
The nickel-titanium alloy is a shape memory alloy, the shape memory alloy is a special alloy which can automatically restore the self plastic deformation to the original shape at a certain specific temperature, has good plasticity, and the corrosion resistance of the shape memory alloy is superior to that of the best medical stainless steel at present, so the nickel-titanium alloy can meet the application requirements of various engineering and medicine, and is a very excellent functional material.
In view of the above, the present invention provides a nitinol stent in a human body lumen to solve the technical problems in the prior art.
Disclosure of Invention
Based on the technical problems in the background art, the invention provides a nickel-titanium alloy stent in a human body lumen.
The invention provides a nickel-titanium alloy stent in a human body lumen, which comprises a stent main body, wherein the stent main body is composed of a plurality of sections of stent frameworks distributed in a shape like a Chinese character 'ji', a framework connecting line is arranged between each section of stent framework, a telescopic net structure is formed between the stent frameworks and the framework connecting line, the stent frameworks and the framework connecting line are integrally formed by nickel-titanium alloy 3D printing, annular ports are arranged at two ends of the stent main body and are formed by connecting a plurality of oval ring bodies end to end, the side surfaces of the ring bodies are connected with the stent frameworks through the framework connecting line, and the cross sections of the stent frameworks, the annular ports and the framework connecting line are all oval structures.
In the invention, preferably, grooves are arranged on the inner sides of the two sections of the support frameworks close to the annular port, elastic pieces are arranged in the grooves, and the elastic pieces are positioned at the middle section of the support frameworks.
In the present invention, preferably, the outside of the groove is coated with a dissolution coating.
In the invention, preferably, an arc-shaped bulge is arranged on the inner side of the groove and is positioned at the joint of the elastic piece and the groove.
In the present invention, preferably, the outer surface of the dissolution coating layer is provided with a plurality of dents.
In the invention, preferably, the elastic part comprises an elastic root section and a thrombus intercepting section which are made of nickel-titanium alloy materials, the section of the thrombus intercepting section is of a triangular structure, and densely distributed pits are arranged on the outer side of the outside of the thrombus intercepting section.
In the invention, the elastic part preferably comprises an elastic root section made of nickel-titanium alloy material and a thrombus intercepting section made of thrombolytic drugs, and a plurality of segmented rings are arranged outside the thrombus intercepting section.
Compared with the prior art, the invention provides a nickel-titanium alloy stent in a human body lumen, which has the following beneficial effects:
according to the invention, two port parts of the stent main body are connected end to form an annular port, after the stent is expanded, the port parts are smooth and stable, the adhesion and friction between the port parts and the wall of a blood vessel cavity are increased, meanwhile, after the annular port is expanded, the port parts form effective support, and the port parts cannot shrink due to the creeping of the wall of the blood vessel cavity, so that the stability of stent fixation is improved.
Drawings
FIG. 1 is a schematic structural view of a nickel-titanium alloy stent in a human body lumen according to the present invention;
FIG. 2 is a schematic view of the deployment structure of a nickel-titanium alloy stent in a human body lumen according to the present invention;
FIG. 3 is a cross-sectional structural diagram of a stent framework of a nickel titanium alloy stent in a human body lumen according to the present invention;
FIG. 4 is a schematic view of an expanded structure of an elastic member of a nickel-titanium alloy stent in a human body lumen according to the present invention;
FIG. 5 is a schematic view of a contracting structure of an elastic member of a nickel-titanium alloy stent in a human body lumen according to the present invention;
FIG. 6 is a schematic structural view of an elastic member of a nickel-titanium alloy stent in a human body lumen according to the present invention;
FIG. 7 is a schematic view of a releasing structure of an elastic member of a nickel titanium alloy stent in a human body lumen according to the present invention;
FIG. 8 is a schematic structural view of an elastic member of a nickel titanium alloy stent in a human body lumen according to embodiment 1 of the present invention;
FIG. 9 is a schematic structural view of an elastic member of a nickel-titanium alloy stent in a human body lumen according to embodiment 2 of the present invention;
fig. 10 is a schematic structural view of a nitinol stent in a human body lumen after an elastic member is dissolved according to embodiment 2 of the present invention.
In the figure: 1 stent framework, 101 grooves, 102 arc-shaped bulges, 103 elastic pieces, 1031 elastic root sections, 1032 thrombus interception sections, 1033 segmental rings, 104 dissolution coatings, 2 annular ports and 3 framework connecting lines.
Detailed Description
Reference will now be made in detail to embodiments of the present patent, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the drawings are illustrative only for the purpose of explaining the present patent and are not to be construed as limiting the present patent.
Example 1:
referring to fig. 1-8, a nickel-titanium alloy stent in a human body lumen comprises a stent main body, wherein the stent main body is composed of a plurality of segments of stent skeletons 1 distributed in a shape like Chinese character ji, a stent connecting wire 3 is arranged between each segment of stent skeleton 1, a telescopic net structure is formed between the stent skeleton 1 and the stent connecting wire 3, the stent skeleton 1 and the stent connecting wire 3 are integrally printed by nickel-titanium alloy 3D, two ends of the stent main body are respectively provided with an annular port 2, the annular ports 2 are formed by connecting a plurality of oval ring bodies end to end, the side surfaces of the ring bodies are connected with the stent skeleton 1 through the stent connecting wire 3, and the cross sections of the stent skeleton 1, the annular ports 2 and the stent connecting wire 3 are all oval structures;
according to the invention, two port parts of the stent main body are connected end to form the annular port 2, after the stent is expanded, the port parts are smooth and stable, the adhesion and friction between the port parts and the wall of a blood vessel cavity are increased, meanwhile, after the annular port 2 is expanded, the port parts form effective support, and can not be contracted by the creeping of the wall of the blood vessel cavity, so that the stability of stent fixation is improved, meanwhile, the cross sections of the stent framework 1, the annular port 2 and the framework connecting line 3 which form the stent are all of an elliptical structure, the contact area of the outer side of the stent and the wall of the cavity is increased, so that the depression formed in soft tissues in the wall of the blood vessel cavity is avoided, the displacement of the stent is caused when a patient moves and the creeping of the wall of the blood vessel cavity is reduced, and the stability of stent placement is further improved.
As a further scheme of the invention, the inner sides of two sections of stent frameworks 1 close to the annular port 2 are provided with grooves 101, the inner parts of the grooves 101 are provided with elastic pieces 103, the elastic pieces 103 are positioned at the middle section of the stent frameworks 1, after the nickel-titanium alloy stent is expanded in a human body lumen, the elastic pieces 103 positioned at the inner sides of the stent frameworks 1 at two ends of the stent are popped out from the inner parts of the grooves 101, two thrombus trapping areas distributed spirally are formed in the lumen, and when thrombus clot appears in the lumen, the thrombus clot is trapped by the funnel-shaped elastic pieces 103, so that the thrombus clot is effectively prevented from flowing.
As a further scheme of the invention, the outer side of the groove 101 is coated with the dissolution coating 104, when the elastic part 103 is implanted into the stent, the outer side of the groove 101 is coated with the dissolution coating 104 formed by thrombolytic drugs, so that the expansion deformation of the elastic part 103 is blocked, and the elastic part 103 is released from the inner part of the groove 101 after the dissolution coating 104 is absorbed along with the flow of blood in the cavity, thereby forming the thrombus trapping funnel, and through the arrangement of the dissolution coating 104, the elastic part 103 is prevented from influencing the intracavity delivery and placement of the stent, meanwhile, after the stent is placed, the thrombolytic drugs are slowly dissolved and released, and the formation of thrombus is effectively avoided.
As a further scheme of the present invention, an arc-shaped protrusion 102 is disposed inside the groove 101, the arc-shaped protrusion 102 is located at a connection position of the elastic member 103 and the groove 101, the arc-shaped protrusion 102 is composed of thrombolytic drugs, the elastic member 103 is expanded by the lever action of the arc-shaped protrusion 102, the intercepted thrombus clot is rapidly dissolved along with the dissolution of the drugs constituting the arc-shaped protrusion 102, and meanwhile, after the arc-shaped protrusion 102 is absorbed, the lever fulcrum at the positions of the elastic member 103 and the groove 101 disappears, and the elastic member 103 retracts into the elastic member 103, thereby avoiding the influence on the blood flow.
As a further scheme of the present invention, the outer surface of the dissolution coating 104 is provided with a plurality of indentations, the indentations are arranged to form a plurality of connection segments from the dissolution coating 104, the contact area with the dissolution coating 104 is increased during blood flow, the dissolution speed of the dissolution coating 104 is controlled by the arrangement of the number of indentations, the phenomena of fracture and peeling of the nitinol stent during expansion are avoided, and the stability of the dissolution coating 104 during the stent implantation stage is improved.
As a further scheme of the present invention, the elastic member 103 includes an elastic root section 1031 and a thrombus blocking section 1032 made of nickel-titanium alloy material, and the section of the thrombus blocking section 1032 is in a triangular structure, and densely distributed pits are provided on the outer side of the outside of the thrombus blocking section 1032, which increases friction on the surface of the thrombus blocking section 1032, improves efficiency of trapping thrombus clots, and prevents the thrombus clots from slipping off after being trapped, and meanwhile, the shape of the thrombus blocking section 1032 is in a triangular structure, which can generate fine jitter during blood flow, increases contact effect between the thrombus clots and thrombolytic drugs, and improves speed of thrombus ablation.
Example 2:
referring to fig. 1-7 and 9-10, a nickel-titanium alloy stent in a human body lumen, an elastic member 103 comprises an elastic root section 1031 made of nickel-titanium alloy material and a thrombus intercepting section 1032 made of thrombus dissolving drugs, a plurality of section rings 1033 are arranged on the outer side of the thrombus intercepting section 1032, the density of the drugs making up the thrombus intercepting section 1032 is greater than the density of the drugs in a dissolving coating 104 and an arc-shaped protrusion 102, so that the thrombus intercepting section 1032 has a longer dissolving speed, and the section rings 1033 are arranged in a sectional and dispersing mode to improve the dissolving speed of thrombus clots when the thrombus clots are intercepted, and meanwhile, after the thrombus intercepting section 1032 is completely dissolved, the elastic member 103 only remains the elastic root section 1031, the distance between the elastic members 103 is shortened, and the use safety of the stent is improved.
When using, after the support extension, its port position is level and smooth stable, increase and the blood vessel cavity wall between adhere to and the friction, and simultaneously, the back is opened to cyclic annular port 2 extension, the port position forms effective support, can not receive the wriggling of blood vessel cavity wall and shrink, improve the fixed stability of support, and simultaneously, the support skeleton 1 that constitutes the support, the section of cyclic annular port 2 and skeleton connecting wire 3 is oval structure, its outside increases with the cavity wall area of contact, avoid forming the cave in the soft tissue in the blood vessel cavity wall, when reducing the patient motion, when the wriggling of blood vessel cavity wall, cause the support displacement.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (7)

1. The utility model provides a nickel titanium alloy support in human lumen, includes the support main part, its characterized in that, the support main part is support skeleton (1) that "nearly" font distributes by the multistage and constitutes, and is provided with skeleton connecting wire (3) between every section support skeleton (1), constitute scalable network structure between support skeleton (1) and skeleton connecting wire (3), and support skeleton (1) and skeleton connecting wire (3) print integrative the constitution by nickel titanium alloy 3D, the both ends of support main part all are provided with cyclic annular port (2), and cyclic annular port (2) comprise a plurality of oval ring body end to end, and the ring body side is connected with support skeleton (1) through skeleton connecting wire (3), the section of support skeleton (1), cyclic annular port (2) and skeleton connecting wire (3) is oval structure.
2. The nickel-titanium alloy stent in the human body lumen according to claim 1, wherein a groove (101) is arranged at the inner side of the two sections of the stent framework (1) close to the annular port (2), an elastic member (103) is arranged in the groove (101), and the elastic member (103) is positioned at the middle section of the stent framework (1).
3. A nitinol stent in a human body lumen according to claim 2, wherein the outside of the groove (101) is coated with a dissolving coating (104).
4. The nitinol stent in the human body lumen according to claim 3, wherein the inner side of the groove (101) is provided with an arc-shaped protrusion (102), and the arc-shaped protrusion (102) is positioned at the connection part of the elastic member (103) and the groove (101).
5. The nitinol stent in a human lumen according to claim 3, wherein the outer surface of the solvent coating (104) is provided with a plurality of indentations.
6. A nickel-titanium alloy stent in a human body lumen according to any one of claims 1-5, characterized in that the elastic part (103) comprises an elastic root section (1031) made of nickel-titanium alloy material and a thrombus intercepting section (1032), the section of the thrombus intercepting section (1032) is in a triangular structure, and the outer side of the thrombus intercepting section (1032) is provided with densely distributed pits.
7. A Nitinol stent according to any of claims 1-5, characterized in that the elastic member (103) comprises an elastic root section (1031) of Nitinol material and a thrombus interception section (1032) of thrombolytic drug, the outside of the thrombus interception section (1032) being provided with a plurality of segmented rings (1033).
CN202210558825.XA 2022-05-21 2022-05-21 Nickel-titanium alloy stent in human body lumen Pending CN114917067A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210558825.XA CN114917067A (en) 2022-05-21 2022-05-21 Nickel-titanium alloy stent in human body lumen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210558825.XA CN114917067A (en) 2022-05-21 2022-05-21 Nickel-titanium alloy stent in human body lumen

Publications (1)

Publication Number Publication Date
CN114917067A true CN114917067A (en) 2022-08-19

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210558825.XA Pending CN114917067A (en) 2022-05-21 2022-05-21 Nickel-titanium alloy stent in human body lumen

Country Status (1)

Country Link
CN (1) CN114917067A (en)

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