CN114903488A

CN114903488A - Fabric electrocardio-electrode and preparation method and application thereof

Info

Publication number: CN114903488A
Application number: CN202210542724.3A
Authority: CN
Inventors: 方剑; 王责默; 戚灵云
Original assignee: Suzhou University
Current assignee: Suzhou University
Priority date: 2022-05-18
Filing date: 2022-05-18
Publication date: 2022-08-16

Abstract

The invention belongs to the field of textile materials, and particularly relates to a fabric electrocardioelectrode as well as a preparation method and application thereof. The product prepared by the preparation method is used for preparing a dry electrode by using static self-assembly PEI/MXene on the cloth with fluff on the surface, so that the high conductivity of the product and the conformal contact with the skin are realized. The invention can effectively reduce the skin contact impedance, maintain the flexibility and the air permeability of the fabric and effectively monitor the electrocardiosignal for a long time. The selected cloth with the surface having the special villus structure can increase the contact area with the skin after contacting with the skin, and the fabric is endowed with good conductivity and low skin contact resistance by a static self-assembly method. In addition, the processed sample can still keep good flexibility, and good use experience is provided for users. The development of the flexible wearable electrocardio-electrode is innovative.

Description

Fabric electrocardio-electrode and preparation method and application thereof

Technical Field

The invention belongs to the field of textile materials, and particularly relates to a fabric electrocardioelectrode as well as a preparation method and application thereof.

Background

With the development of intelligent wearable technology, people pay more and more attention to intelligent monitoring clothes. The flexible bioelectricity dry electrode can be used for collecting physiological electric signals of a human body, such as electrocardio signals, electroencephalogram signals and the like, and is an important component of intelligent monitoring clothes. According to the data, the cardiovascular disease prevalence is in a continuously rising phase. Real-time monitoring is realized through wearable monitoring equipment, patients, especially elderly people, are helped, the purposes of early discovery and early treatment are realized, and the death rate of cardiovascular diseases is reduced. The Ag/AgCl gel electrode is the most commonly used electrode in the electrocardiographic monitoring. However, the hydrogel in the middle of these electrodes tends to lose water, thereby affecting its performance. In addition, after prolonged contact with these electrodes, the user may experience allergies and inflammation.

The dry electrode with the flexible polymer substrate can avoid the electrode from being easy to dry, but has poor air permeability and poor comfort in long-term measurement. The common fabric electrode has small contact area with the skin, so that large skin contact impedance is caused, and the common fabric electrode has certain influence on the accuracy of electrocardio measurement.

Therefore, it is necessary to invent a flexible villus fabric electrocardio-electrode, which not only can reduce the skin contact impedance and stably monitor the electrocardio-signal, but also can ensure the flexibility and the air permeability of the material.

In the Chinese document, namely the preparation and performance of corduroy electrocardiac fabric electrodes, the electrocardiac electrodes are prepared by using corduroy as a substrate and carrying out polyaniline in-situ polymerization and chemical silver plating, the preparation process is complex, and the reaction time is long. The contact impedance of the skin electrode is large and is less than 1000k omega within the frequency of 5-500 Hz.

CN2016101151084 invented a flexible electrocardio-electrode for dynamic electrocardio-measurement that can eliminate the skin electric interference. Adopt flexible substrate, stereoplasm micropin array, conducting layer and insulating layer to constitute, its problem lies in: the microneedles pierce the skin causing skin injury; polymer Polydimethylsiloxane (PDMS) is used as a substrate, the air permeability of the electrode is poor, the electrode is not suitable for long-time wearing, and meanwhile, the electrode flexibility is poor and the wearing comfort is poor due to the hard micro-needle.

Disclosure of Invention

In order to solve the technical problem, the invention provides a preparation method of a fabric electrocardioelectrode, which comprises the following steps:

s1: adding the fabric into a PEI (polyethyleneimine) solution, and reacting to obtain a treated fabric A;

s2: adding the treated fabric A into MXene solution, and reacting to obtain a treated fabric B;

s3: repeating the steps S1 and S2 for 6-12 times by taking the treated fabric B as a fabric to obtain a conductive fabric;

s4: and adhering the conductive fabric to a medical bandage with an electrode buckle to obtain the fabric electrocardio-electrode.

Preferably, the fabric is made of 21 pieces of corduroy, chenille fabric or polar fleece.

Preferably, in the step S1, the fabric needs to be pretreated before being added into the PEI solution; the pretreatment method comprises the steps of cleaning the fabric in water for 1-3h, drying the fabric, and cleaning the fabric in ethanol for 1-3 h.

Preferably, in the PEI solution, the molecular weight of PEI is 60000-80000.

Further, the PEI solution is obtained by dispersing PEI in water at 20-30 ℃ for 6-8 h.

Further, the concentration of the PEI solution is 0.1-2.0 mg/mL.

Preferably, the concentration of the MXene solution is 3-5 mg/mL.

Preferably, in the step S1, the fabric and the PEI solution are mixed, washed with water for 3-5min, and dried at 60-80 ℃ for 1-3h to obtain the treated fabric A.

Preferably, in the step S2, the treated fabric a and the MXene solution are mixed, washed with water for 3-5min, and dried at 60-80 ℃ for 2-3h to obtain the treated fabric B.

The invention also provides the fabric electrocardioelectrode prepared by the preparation method.

The invention also provides an electrocardiosignal acquisition device which comprises a working electrode, an auxiliary electrode and a reference electrode, wherein the working electrode is the fabric electrocardioelectrode.

Preferably, the auxiliary electrode and the reference electrode are both gel electrodes.

The invention also provides application of the electrocardiosignal acquisition device in electrocardiosignal acquisition.

Preferably, the application comprises the following steps: and adhering the electrocardiosignal acquisition device to a human body, measuring the impedance of the skin electrode contact through an electrochemical workstation, and recording the impedance value.

Compared with the prior art, the technical scheme of the invention has the following advantages:

the product prepared by the preparation method is used for preparing a dry electrode by using static self-assembly PEI/MXene on the cloth with fluff on the surface, so that the high conductivity of the product and the conformal contact with the skin are realized. By the preparation method, the skin contact impedance can be effectively reduced, the flexibility and the air permeability of the fabric are kept, and the electrocardiosignal can be effectively monitored for a long time.

The invention has the innovation points that the selected cloth with the special fluff structure on the surface can increase the contact area with the skin after contacting with the skin, and the fabric is endowed with good conductivity and low skin contact resistance by a static self-assembly method. In addition, the processed sample can still keep good flexibility, and good use experience is provided for users. The development of the flexible wearable electrocardio-electrode is innovative.

Drawings

FIG. 1 is a flow chart of the manufacturing process of the high-efficiency fabric electrocardio-electrode of the invention.

Fig. 2 shows, from left to right, a physical representation of 21 strips of corduroy, chenille and polar fleece, respectively.

Figure 3 is a view of a fabric electrode structure.

FIG. 4 is a scanning electron microscope image of a product before and after an electrostatic self-assembly experiment; (a) and (b) and (c) are 21 pieces of corduroy, chenille and polar fleece respectively.

Figure 5 is the skin contact impedance of the 21 strips of wick pile fabric, chenille fabric, polar fleece fabric and commercial gel electrode of the product.

Description of reference numerals: 1-electrode button, 2-medical bandage and 3-conductive fabric.

Detailed Description

The present invention is further described below in conjunction with the following figures and specific examples so that those skilled in the art may better understand the present invention and practice it, but the examples are not intended to limit the present invention.

Example 1

The first step is as follows: pretreating the fabric, selecting 21 lamp core velvet fabrics of 10cm multiplied by 10cm, and putting the velvet fabrics into ethanol and deionized water for ultrasonic cleaning for a period of time.

The second step is that: preparing a solution, namely PEI with the molecular weight of 70000, dispersing into an aqueous solution through magnetic stirring at normal temperature, selecting high-concentration MXene, and performing ultrasonic dispersion by using a probe; the concentration of the PEI solution is 1 mg/mL; the concentration of MXene solution was 3 mg/mL.

The third step: and putting the cloth into a PEI solution for ultrasonic cleaning for a period of time, then ultrasonic cleaning in deionized water for a period of time, and putting the cloth into a vacuum drying oven for drying.

The fourth step: and (3) placing the dried cloth into MXene solution for ultrasonic cleaning for a period of time, then ultrasonically cleaning in deionized water for 5min, and placing the cloth into a vacuum drying oven to dry for 2h at 60 ℃.

The fifth step: repeating the above process for self-assembly 10 times to obtain the conductive fabric.

And a sixth step: and (3) assembling the fabric electrode, namely buckling the electrode buckle on the medical bandage, and then adhering the conductive fabric on the surface adhered by the medical bandage to obtain the fabric electrocardioelectrode.

Example 2

The second step: preparing a solution, namely PEI with a molecular weight of 25000, dispersing into an aqueous solution through magnetic stirring at normal temperature, selecting high-concentration MXene, and performing ultrasonic dispersion by using a probe; the concentration of the PEI solution is 1 mg/mL; the concentration of MXene solution was 3 mg/mL.

Example 3

The second step is that: preparing a solution, namely PEI with the molecular weight of 70000, dispersing into an aqueous solution through magnetic stirring at normal temperature, selecting high-concentration MXene, and performing ultrasonic dispersion by using a probe; the concentration of the PEI solution is 1 mg/mL; the concentration of MXene solution was 4 mg/mL.

Example 4

The first step is as follows: pretreating the fabric, selecting 21 lamp core velvet fabrics of 10cm multiplied by 10cm, and putting the fabrics into ethanol and deionized water for ultrasonic cleaning for a period of time.

The second step is that: preparing a solution, namely PEI with a molecular weight of 25000, dispersing into an aqueous solution through magnetic stirring at normal temperature, selecting high-concentration MXene, and performing ultrasonic dispersion by using a probe; the concentration of the PEI solution is 1 mg/mL; the concentration of MXene solution was 4 mg/mL.

Example 5

The second step is that: preparing a solution, namely PEI with the molecular weight of 70000, dispersing into an aqueous solution through magnetic stirring at normal temperature, selecting high-concentration MXene, and performing ultrasonic dispersion by using a probe; the concentration of the PEI solution is 1 mg/mL; the concentration of MXene solution was 5 mg/mL.

Example 6

The second step is that: preparing a solution, namely PEI with a molecular weight of 25000, dispersing into an aqueous solution through magnetic stirring at normal temperature, selecting high-concentration MXene, and performing ultrasonic dispersion by using a probe; the concentration of the PEI solution is 1 mg/mL; the concentration of MXene solution was 5 mg/mL.

Example 7

The second step is that: preparing a solution, namely PEI with the molecular weight of 70000, dispersing into an aqueous solution through magnetic stirring at normal temperature, selecting high-concentration MXene, and performing ultrasonic dispersion by using a probe; the concentration of the PEI solution is 2 mg/mL; the concentration of MXene solution was 3 mg/mL.

The fourth step: and (3) placing the dried cloth into MXene solution for ultrasonic cleaning for a period of time, then ultrasonically cleaning in deionized water for 3min, and placing the cloth into a vacuum drying oven to dry for 2h at 60 ℃.

And a sixth step: the fabric electrode assembly is characterized in that firstly, the electrode buckle is buckled on the medical bandage, and then the conductive fabric is adhered to the adhered surface of the medical bandage to obtain the fabric electrocardioelectrode.

Example 8

The first step is as follows: pretreating the fabric, selecting 21 lamp core velvet materials of 10cm multiplied by 10cm, and putting the velvet materials into ethanol and deionized water for ultrasonic cleaning for a period of time.

The second step is that: preparing a solution, namely PEI with a molecular weight of 25000, dispersing into an aqueous solution through magnetic stirring at normal temperature, selecting high-concentration MXene, and performing ultrasonic dispersion by using a probe; the concentration of the PEI solution is 2 mg/mL; the concentration of MXene solution was 3 mg/mL.

The third step: and putting the cloth into a PEI solution for ultrasonic cleaning for a period of time, then ultrasonically cleaning the cloth in deionized water for a period of time, and putting the cloth into a vacuum drying oven for drying.

Example 9

The first step is as follows: pretreating the fabric, selecting chenille fabric of 10cm multiplied by 10cm, and putting the chenille fabric into ethanol and deionized water for ultrasonic cleaning for a period of time.

The fifth step: repeating the process for self-assembly for 10 times to obtain the conductive fabric.

Example 10

The first step is as follows: pretreating the fabric, selecting a polar fleece fabric of 10cm multiplied by 10cm, and putting the polar fleece fabric into ethanol and deionized water for ultrasonic cleaning for a period of time.

Evaluation of Effect

Sticking the medical bandage to a human body as a working electrode by adopting a three-electrode connection mode; auxiliary and reference electrodes the impedance of the skin electrode contact was measured by an electrochemical workstation using a commercial gel electrode and the impedance values were recorded.

As shown in the Scanning Electron Microscope (SEM) image of fig. 4, after self-assembly, the textile maintained its original structure, with well separated and continuously aligned MXene flakes intimately coated on the fiber surface.

After electrostatic self-assembly, the resistivity of 21 lamp-core velvet fabrics is 1.077 omega cm, the resistivity of chenille fabrics is 2.132 omega cm, and the resistivity of polar fleece fabrics is 2.477 omega cm, so that the fabric has good conductivity.

The electrocardiosignals are directly influenced by the contact impedance of the skin electrode. The low contact impedance helps to reduce noise and accurately acquire the cardiac electrical signal. The reason for using a gel electrode is that it can make conformal contact with the skin, thereby reducing the skin electrode contact resistance.

According to the invention, the skin contact impedance: 21 corduroy is less than chenille and less than polar fleece, and the electrode impedance of the 21 corduroy is 376.1k omega/cm at 1Hz ² . This is because the villus structure on the surface of 21 lamp core villus fabrics can increase the contact area of the electrode and the skin surface, thereby realizing conformal contact.

It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Various other modifications and alterations will occur to those skilled in the art upon reading the foregoing description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications of the invention may be made without departing from the spirit or scope of the invention.

Claims

1. The preparation method of the fabric electrocardio-electrode is characterized by comprising the following steps:

s1: adding the fabric into a PEI solution, and reacting to obtain a treated fabric A; the fabric is made of 21 corduroy, chenille fabric or polar fleece;

2. The method of claim 1, wherein the molecular weight of the PEI is 60000 and 80000.

3. The method of claim 1 or 2, wherein the PEI solution is prepared by dispersing PEI in water at 20-30 ℃ for 6-8 hours.

4. The method of claim 1 or 2, wherein the PEI solution is at a concentration of 0.1 to 2.0 mg/mL.

5. The method of claim 1, wherein the concentration of the MXene solution is 3-5 mg/mL.

6. A fabric electrocardio-electrode prepared by the preparation method of any one of claims 1 to 5.

7. An electrocardiosignal acquisition device, which is characterized by comprising a working electrode, an auxiliary electrode and a reference electrode, wherein the working electrode is the fabric electrocardioelectrode of claim 6.

8. The cardiac signal acquisition device as set forth in claim 7, wherein the auxiliary electrode and the reference electrode are both gel electrodes.

9. Use of an apparatus according to claim 7 or 8 for acquiring an electrical cardiac signal.

10. Use according to claim 9, characterized in that it comprises the following steps: and adhering the electrocardiosignal acquisition device to a human body, measuring the impedance of the skin electrode contact through an electrochemical workstation, and recording the impedance value.