CN114882099A - Coronary blood vessel blood supply amount analysis device and operation method - Google Patents

Coronary blood vessel blood supply amount analysis device and operation method Download PDF

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Publication number
CN114882099A
CN114882099A CN202210428598.9A CN202210428598A CN114882099A CN 114882099 A CN114882099 A CN 114882099A CN 202210428598 A CN202210428598 A CN 202210428598A CN 114882099 A CN114882099 A CN 114882099A
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heart
blood supply
coronary artery
image
cross
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裴海峰
马鑫
高亮
谭彦宏
闵波
杨伟
邹洪
吴群
杨旭虎
刘新忠
余洛海
吕立远
郭国峰
杨兵
安豫
许鲁平
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950th Army Hospital Of Chinese Pla
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    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/60—Analysis of geometric attributes
    • G06T7/62—Analysis of geometric attributes of area, perimeter, diameter or volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/02028—Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A61B5/029—Measuring or recording blood output from the heart, e.g. minute volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/02—Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/027—Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis characterised by the use of a particular data acquisition trajectory, e.g. helical or spiral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/02—Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computerised tomographs
    • A61B6/032—Transmission computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50—Clinical applications
    • A61B6/504—Clinical applications involving diagnosis of blood vessels, e.g. by angiography
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/20—ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
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    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
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    • G06T2207/10—Image acquisition modality
    • G06T2207/10072—Tomographic images
    • G06T2207/10081—Computed x-ray tomography [CT]
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10072—Tomographic images
    • G06T2207/10088—Magnetic resonance imaging [MRI]
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10116—X-ray image
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10132—Ultrasound image
    • G—PHYSICS
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    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
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    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30048—Heart; Cardiac
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30061—Lung

Abstract

The invention provides a coronary blood vessel blood supply quantity analysis device and an operation method thereof, wherein the analysis device comprises a processor and a memory, the analysis operation executed by the processor comprises the steps of calculating a coronary blood vessel blood supply quantity coefficient, and comparing the blood supply quantity coefficient with a preset coefficient value to obtain whether the heart blood supply state is ischemic. The operation method of the device comprises the steps of introducing an image picture of the cross section of the heart, obtaining the sum of the heart height and the blood flow of the left coronary artery and the right coronary artery of the heart, then carrying out area calculation on the image belonging to the heart to obtain the heart area at the maximum cross section of the heart, and calculating the coefficient of the heart volume through the area and the heart height; calculating a blood supply coefficient according to the heart volume coefficient and the blood flow sum data; and comparing the blood supply quantity coefficient with a preset coefficient value to obtain the heart blood supply state. The invention objectively analyzes whether the blood supply volume of the heart is sufficient or not according to the relation between the heart volume and the blood supply volume.

Description

Coronary blood vessel blood supply amount analysis device and operation method
Technical Field
The invention relates to a computer technology, in particular to a coronary blood vessel blood supply volume analysis device and an operation method.
Background
The heart coronary artery is an arterial blood vessel for supplying blood to the heart muscle. For short, coronary vessels, the coronary arteries of the heart include the left and right coronary arteries.
Coronary artery blockage can be caused by heart coronary atherosclerotic plaque, or hardening, calcification or fat adhesion on the inner wall of a blood vessel, and the blockage of the blood vessel can cause lumen stenosis and insufficient blood supply, so that the patient has myocardial infarction and the life of the patient is threatened.
Thus, there is a need to protect the heart by supplying sufficient blood to the heart muscle from the coronary vessels.
However, for coronary vessels supplying blood to the heart myocardium, it is common to determine whether the blood supply is sufficient by performing coronary angiography to determine the stenosis rate of the coronary vessels. The stenosis rate of the blood vessel is not equal to the blood supply rate, that is, the coronary blood supply is insufficient in the case that the blood vessel is not narrowed, or the coronary blood supply still satisfies the cardiac muscle in the case that the blood vessel has a certain obstruction. Therefore, the best way to view coronary blood supply should be determined from the specific blood supply and there is currently no corresponding device to solve this problem.
Disclosure of Invention
In order to solve the technical problem, the invention provides a coronary blood supply analysis device in a first aspect, and provides an operation method of the analysis device in a second aspect.
The coronary blood supply volume analysis device according to the first aspect of the present invention includes a processor, and a memory, in which a computer program is stored, wherein when the computer program is executed by the processor, the processor performs the following operations:
s1: calculating the blood supply coefficient of coronary vessels; the blood supply volume coefficient is obtained by the following formula:
Figure BDA0003609155850000011
in the formula, q is the sum of blood flow of the left coronary artery and the right coronary artery of the heart, and f is the volume parameter of the heart;
s2: judging the blood supply state level of the coronary artery of the heart through the blood supply coefficient, specifically, storing a preset coefficient value in the memory, and comparing the blood supply coefficient with the preset coefficient value to obtain the blood supply state of the heart; the state of blood supply to the heart includes whether the heart is in an ischemic state.
In the coronary blood supply amount analysis device according to the first aspect, the blood flow rate of the right coronary artery of the heart and the blood flow rate of the left coronary artery of the heart are both obtained by:
obtaining the cross-sectional area and the blood flow velocity of the vascular orifice of the right coronary artery and the left coronary artery of the heart respectively through blood flow color ultrasound;
the blood flow of the right coronary artery and the left coronary artery of the heart is obtained by the formula q va, where v is the blood flow velocity and a is the cross-sectional area of the vascular orifice.
The coronary blood vessel blood supply amount analysis device according to the first aspect, wherein the volume parameter is specifically one of the following: a heart global volume comprising a heart internal cavity; a volume of a substantial portion of the cardiac body not containing the internal cavity of the heart; a coefficient representing a volume of the heart;
the whole volume of the heart and the substantial part volume of the heart body are obtained by one of three-dimensional radiography calculation, ultrasonic detection and calculation;
wherein the coefficient of the cardiac volume is obtained by the formula: s.h;
in the formula, the area of the maximum cross section of the S heart, and h is the height of the heart.
The coronary blood supply amount analyzer according to the first aspect of the present invention may be configured such that the area of the largest cross section of the heart is obtained by:
s41: introducing a medical image picture of the cross section of the heart;
s42: receiving a calibration of a cross-sectional image of the heart by a user, the calibration comprising:
dividing an image belonging to the heart and images belonging to other tissues in a heart cross section picture by a user;
marking images belonging to the heart on the divided medical image picture of the heart cross section;
s43: the area of the heart at the largest cross section of the heart is obtained by performing area calculation on the images belonging to the heart.
The coronary artery blood supply analysis device according to the first aspect of the present invention, wherein the image of the cross-sectional medical image of the heart is specifically a cross-sectional medical image of the heart obtained by CT, nuclear magnetic resonance, and spiral CT, wherein the image of the heart, the image of the muscle tissue of the human body, and the image of the bone lattice are composed of gray and white pixels, and the image of the lung is composed of black pixels;
the calibration performed by the user on the heart cross-sectional image specifically comprises the following steps: dividing an image belonging to the heart from a human muscle tissue image and a bone image by a user by using a black pixel brush; an image belonging to the heart is wrapped by a black pixel connected domain, wherein the black pixel connected domain comprises a lung image and an image formed by a brush.
In the coronary blood vessel blood supply amount analysis apparatus according to the first aspect, the cross-sectional cardiac medical image picture is specifically a cross-sectional cardiac medical image picture with the largest cross-sectional area found out from a plurality of cross-sectional cardiac medical image pictures.
The coronary blood supply amount analyzer according to the first aspect of the present invention, wherein the height of the heart is a distance between the apex of the heart and the mouth of the right coronary artery;
the heart height is obtained by one of the ultrasonic image calculations through user input.
The method for operating the coronary blood supply amount analyzing and calculating device according to the second aspect of the present invention is implemented in a computer system having a processor, a memory storing a computer program, and a display screen, and includes:
pushing a data input interface to a user, and receiving a heart cross section medical image picture selected by the user in the input interface;
obtaining the blood flow sum data of the heart height, the left coronary artery and the right coronary artery of the heart;
pushing a picture editing interface to a user, wherein the editing interface displays the heart cross section medical image picture selected by the user and an editing tool; receiving a user to edit the picture, including: in the picture, the user divides the image belonging to the heart from the images belonging to the remaining tissues; marking images belonging to the heart on the divided medical image picture of the heart cross section; calculating the area of the image belonging to the heart to obtain the heart area at the maximum cross section of the heart;
calculating the coefficient of the heart volume according to the area and the height of the heart; calculating a blood supply coefficient according to the coefficient of the heart volume and the blood flow sum data;
and comparing the blood supply quantity coefficient with a preset coefficient value to obtain the heart blood supply state.
The operation method of the coronary blood supply analysis and calculation device according to the second aspect of the present invention, wherein the total data of the heart height, the left coronary artery of the heart and the right coronary artery of the heart is obtained by one of the following methods:
(1) heart height directly entered by the user in the data entry interface;
(2) the blood flow sum data of the left coronary artery and the right coronary artery of the heart is directly input in the data input interface by a user;
(3) the processor calculates and obtains the sum data according to the blood flow data of the left coronary artery and the blood flow data of the right coronary artery of the heart which are directly input by the user in the data input interface.
The method for operating the coronary blood supply analysis and calculation device according to the second aspect comprises the following steps:
the user imports the heart ultrasonic image in the data input interface, marks the heart apex and the right coronary artery mouth in the editing interface, and the processor calculates the heart height according to the positions of the heart apex and the right coronary artery mouth marked by the user.
The beneficial technical effects are as follows:
the device of the invention determines whether the current sum of the blood flow of the left coronary artery and the right coronary artery of the heart can meet the heart blood supply of the heart volume parameter by checking the total blood flow of the left coronary artery and the right coronary artery and calculating the volume parameter of the heart. According to the relation between the heart volume and the blood supply volume, whether the blood supply volume of the heart is sufficient or not is objectively analyzed.
Drawings
In order to more clearly illustrate the technical solutions involved in the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, however, the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art that other drawings can be easily obtained from the drawings without creative efforts.
FIG. 1 is a view showing the construction of a coronary blood supply amount analyzer according to the present invention;
FIG. 2 is a schematic view of a display screen of the present invention;
FIG. 3 is a flowchart illustrating operations performed by a processor;
FIG. 4 is another flow diagram of operations performed by the processor.
Wherein: a processor 01; a bus 02; a communication interface 03; a memory 04; a display screen 05; a picture editing interface 11; a dividing tool 12; a marking tool 13; a data input interface 14; a status bar 15; a heart cross section medical image picture 21; a scale 22.
Detailed Description
The coronary blood supply volume analysis device is formed by installing a corresponding computer program in a computer device, wherein the computer program realizes an operation method of the coronary blood supply volume analysis device.
Referring to fig. 1, the computer of the present invention must have the following composition: processor, memory, display screen 05 and the necessary computer system, and further has a bus 02 and a communication interface 03, wherein the processor 01, the communication interface 03 and the memory 04 are connected via the bus 02. Here, the memory 04 is: including high-speed Random Access Memory (RAM), or external memory (e.g., at least one disk memory, USB interface solid state disk memory). The bus 02 may be an ISA bus, a PCI bus, an EISA bus, or the like. The bus 02 may be divided into an address bus, a data bus, a control bus, etc. The processor 01 is an integrated circuit chip having signal processing capability. Processor 01 of the present invention may be a general purpose processor, such as a Central Processing Unit (CPU); but may also be a Digital Signal Processor (DSP), an Application Specific Integrated Circuit (ASIC), a Field Programmable Gate Array (FPGA) or other programmable logic device, discrete gate or transistor logic device, discrete hardware components. A general purpose processor may be a microprocessor or the processor may be any conventional processor or the like. The steps of the method disclosed in connection with the embodiments of the present application may be directly implemented by a hardware decoding processor, or implemented by a combination of hardware and software modules in the decoding processor.
The cross-sectional image of the heart of the invention is a medical image obtained at the chest cavity by a medical X-ray apparatus or a nuclear magnetic resonance apparatus. Since medical images generally have a characteristic that different image intensities are developed according to the density of a measured object, and structures of a human body required for the medical images are obtained according to the different intensities, for example, in a medical image obtained at a thoracic cavity by using a medical X-ray apparatus, a bone portion (vertebra, rib) of the human body has high-brightness pixels and has a sharp contour, and is displayed in white pixels with relatively large brightness. In addition, the lung in the chest cavity is invisible and is full black pixels, the heart presents a low-brightness foggy image, the muscle of the human body also presents a low-brightness foggy image, and the heart image is connected with the chest muscle part of the human body, so that the heart image is not beneficial to distinguishing.
Referring to fig. 2, in one example, the coronary blood supply analysis device has a display screen 05, in the display screen 05, at least a data input interface 14 is shown to the user, the data input interface has an "import image" button, when the user clicks the "import image" button, a user folder can be opened, and the user selects a suitable heart cross-sectional medical image picture in the folder, and the selection criteria are: among the several pictures, the picture taken at the maximum cross section of the heart was chosen, which is approximately 3/4 from top to bottom, since the heart is generally inversely tapered. The data input interface has a heart cross-sectional picture window that displays the picture just imported. The data input interface 14 has data input boxes, one example of which is a data input box including:
height input box for heart height directly input by the user.
A summation input box for the user directly inputting blood flow summation data of the left coronary artery and the right coronary artery of the heart.
Alternatively, the device also has a heart left coronary artery blood flow data input box and a heart right coronary artery blood flow data input box which are directly input by a user.
Or, the input box also has the input box of the directly input heart left coronary artery blood speed and coronary artery ostium diameter, and the input box of the directly input heart right coronary artery blood speed and coronary artery ostium diameter.
In the display screen, at least a picture editing interface 11 is displayed for a user, and the editing interface is provided with a large window for displaying a heart cross section medical image picture 21 selected by the user and an editing tool; the editing tool can edit pictures, so that there are two main editing tools: 1. the dividing tool is used for dividing the image belonging to the heart and the image belonging to other tissues by a user, when the dividing tool 12 is clicked, a cursor of a computer mouse is changed into a virtual pen point, a black line with the dividing width of about 1-3mm is formed at the position which is crossed by the virtual pen point, when the black line is connected with other black pixels including the lung in the chest cavity on the picture, the heart image is isolated, and therefore the dividing tool can manually divide the joint of the heart image and the chest circumference muscle part of the human body. 2. Marking means for marking images belonging to the heart on the segmented cardiac cross-sectional medical image; when the marking tool 13 is activated, after the isolated heart image is clicked by the computer mouse, all the images having non-black pixel connection with the clicked portion, that is, the clicked non-black pixel connected domain is selected and marked as the heart image. The cardiac image is marked for area calculation to obtain the cardiac area at the maximum cross section of the heart.
The display screen at least has the finally calculated heart blood supply state, and shows the results of good blood supply, insufficient blood supply, suspected blood supply and the like.
Of course, the display screen also has at least settings such as a virtual button for closing the program, controlling the interface window, a program status bar 15, and the like.
Referring to fig. 3, one example of this is that in the coronary blood vessel blood supply amount analysis device, the operation process is as follows:
s1: and pushing a data input interface to the user, and receiving the cross-sectional medical image picture of the heart selected by the user in the input interface.
S2: obtaining the blood flow sum data of the heart height, the left coronary artery and the right coronary artery of the heart;
one preferred method of obtaining heart height is: the heart height entered directly by the user in the data entry interface. The heart height data source of the user can be heart height data calculated by the patient in other color ultrasound images or heart height measured by the patient in other medical image modes.
With the heart height directly entered in the data entry interface, the source of the heart height data may be extensive, for example with the aid of data obtained during other examinations, and thus facilitates the implementation of the invention.
The method for obtaining the blood flow sum data of the left coronary artery and the right coronary artery of the heart comprises the following two modes:
(1) the sum data of the blood flow of the left coronary artery and the right coronary artery of the heart is directly input in the data input interface by the user.
(2) Or the blood flow data of the left coronary artery and the blood flow data of the right coronary artery of the heart are directly input in the data input interface by a user, and the processor obtains the sum data after calculation. Under the current medical condition, it is very easy to obtain the blood flow signal through the blood flow color ultrasound, and the blood flow signal at least includes the blood flow speed, the blood flow direction and the blood vessel diameter of the coronary artery mouth, so that the data can be easily obtained when the operation color ultrasound is out.
S3: pushing a picture editing interface to a user, wherein the editing interface displays the heart cross section medical image picture selected by the user and an editing tool; the editing tools include at least a dividing tool and a marking tool.
S4: receiving a user to edit the picture, including: in the picture, the user divides the image belonging to the heart from the images belonging to the remaining tissues; because the muscle and the heart image of the human body belong to pixels with low brightness in the CT picture and are connected together, the lung in the chest cavity is invisible and is a full black pixel, a black line with the width of about 1-3mm is formed at the position crossed by the virtual pen point provided by the editing interface to divide the heart image and the muscle of the human body, and the black line and the full black pixel of the lung in the chest cavity are connected into a piece, so that the dividing tool can manually divide the joint of the heart image and the chest muscle of the human body. Isolating the cardiac image.
And on the divided heart cross section medical image picture, adopting a marking tool to click an image belonging to the heart, carrying out absolute value processing on the heart image and normalizing the heart image to be between 0 and 1 due to the fact that the heart image is not all black pixels.
S5: carrying out area calculation on the image belonging to the heart by an integral method to obtain the heart area at the maximum cross section of the heart; or the area calculation is carried out by a pixel number method to obtain the heart area at the maximum cross section of the heart, the image of the medical image at the cross section of the heart contains the information of the image scale 22, the actual area size of the image of one pixel point under the current scale is obtained by calculation, and then the number of pixel points of the image belonging to the heart is counted to obtain the heart area at the maximum cross section of the heart.
S6: calculating the coefficient of the heart volume according to the area and the height of the heart; the formula is as follows:
f＝S.h
in the formula, the area of the maximum cross section of the S heart, and h is the height of the heart.
S7: and calculating a blood supply coefficient according to the coefficient of the heart volume and the blood flow sum data. The formula is as follows:
Figure BDA0003609155850000071
wherein q is the sum of blood flow (in ml/min, i.e. blood supply per minute) of the left coronary artery and the right coronary artery of the heart, and f is the volume parameter of the heart. The main function of the coronary artery is to provide blood flow (containing nutrient substances) to cardiac myocardium, and a certain volume of heart needs a certain amount of blood supply, so that insufficient blood supply can cause insufficient transportation capacity caused by myocardial infarction, and the sizes of different human hearts are different, but the volume of the heart is in direct proportion to the total sum of blood flow, so that the total sum of blood flow needed under the current heart volume coefficient can be measured by calculating the heart volume coefficient. In the present example, the ratio of the heart volume coefficient to the sum of the blood flow rates is used to calculate the blood supply volume coefficient, wherein the heart volume coefficient can be obtained by only multiplying the heart cross-sectional area by the heart height, so that the calculation is simple and can basically represent the size degree of the heart. The cross sectional area of the heart is the cross sectional area at the maximum position of the heart, which is beneficial to reducing errors.
S8: and comparing the blood supply quantity coefficient with a preset coefficient value to obtain the heart blood supply state. If the value is less than the preset coefficient value to a certain extent, the blood supply of the coronary artery of the heart is determined to be suspected to be insufficient or determined to be insufficient.
One example is that the cross-sectional area at the maximum of the heart is measured at 112.04cm 2 The height of the heart is 8.20cm, the obtained volume parameter is 918.72, the obtained coronary blood supply is 83ml/min, and the obtained blood supply coefficient is 0.09034 after the obtained volume parameter is substituted into a blood supply coefficient formula (of course, the obtained blood supply coefficient can be enlarged by 1000 times to obtain 90.34 for convenience of calculation and recording).
The preset coefficient value is set to 0.09 (where the preset coefficient value is obtained by referring to the average value of the blood supply volume of several normal hearts and the heart volume parameter), so that the coronary blood supply volume in this example is larger than the preset coefficient value, and the coronary blood supply volume of the heart can be considered to be normal.
Referring to fig. 4, one example of this is that in the coronary blood vessel blood supply amount analysis device, the operation process is as follows:
s1: and pushing a data input interface to the user, and receiving the cross-sectional medical image picture of the heart selected by the user in the input interface.
S2: obtaining the blood flow sum data of the heart height, the left coronary artery and the right coronary artery of the heart;
among the methods of obtaining heart height are: the heart height is automatically calculated by the system, as follows:
the user imports the heart ultrasonic image in the data input interface, marks the heart apex and the right coronary artery ostium in the editing interface, and the processor calculates the marks of the two positions according to the positions of the heart apex and the right coronary artery ostium marked by the user, wherein the calculated distance is the heart height. The heart ultrasonic image contains image scale information, the actual length size of the image of one pixel point under the current scale is obtained through calculation, and then the number of pixel points between the heart apex and the right coronary artery mouth position is counted, so that the actual length of the heart apex and the right coronary artery mouth position, namely the heart height required by the invention, can be obtained.
In this method, it is required to find the cardiac ultrasound image of the patient or to acquire the ultrasound image again, and the size and pixels of the input ultrasound image are required to be input according to the standard, so the operation is not flexible.
The method comprises the following steps of obtaining blood flow sum data of a left heart coronary artery and a right heart coronary artery, wherein the specific method comprises the following steps:
and the user directly inputs the blood flow sum data of the left coronary artery and the right coronary artery of the heart in the data input interface.
Or the blood flow data of the left coronary artery of the heart and the blood flow data of the right coronary artery of the heart are directly input in the data input interface by a user, and the processor obtains the sum data after calculation.
S3: and pushing the picture editing interface to the user.
S4: receiving a user to edit the picture, including: in the picture, the user divides the image belonging to the heart from the images belonging to the remaining tissues, isolating the heart images. And on the divided heart cross section medical image picture, a marking tool is adopted to find the image belonging to the heart.
S5: the area of the heart at the largest cross section of the heart is obtained by performing area calculation on the images belonging to the heart.
S6: calculating the coefficient of the heart volume according to the area and the height of the heart; the formula is as follows:
f＝S.h
in the formula, the area of the maximum cross section of the S heart, and h is the height of the heart.
S7: and calculating a blood supply coefficient according to the coefficient of the heart volume and the blood flow sum data. The formula is as follows:
Figure BDA0003609155850000081
wherein q is the sum of blood flow (in ml/min, i.e. blood supply per minute) of the left coronary artery and the right coronary artery of the heart, and f is the volume parameter of the heart.
S8: and comparing the blood supply quantity coefficient with a preset coefficient value to obtain the heart blood supply state. If the value is less than the preset coefficient value to a certain extent, the blood supply of the coronary artery of the heart is determined to be suspected to be insufficient or determined to be insufficient.
Referring to fig. 4, one example of this is that in the coronary blood vessel blood supply amount analysis device, the operation process is as follows:
s1: and pushing a data input interface to the user, and receiving the cross-sectional medical image picture of the heart selected by the user in the input interface.
S2: obtaining the blood flow sum data of the left coronary artery and the right coronary artery of the heart, wherein the specific method comprises the following steps:
(1) the sum data of the blood flow of the left coronary artery and the right coronary artery of the heart is directly input in the data input interface by the user.
(2) Or the blood flow data of the left coronary artery and the blood flow data of the right coronary artery of the heart are directly input in the data input interface by a user, and the processor obtains the sum data after calculation.
S3: the cardiac volume parameter of the invention is obtained, in this example the cardiac volume is taken as the cardiac volume parameter, and the cardiac weight is calculated by 3D modeling of the measured heart. When the volume of the heart (the substantial volume remaining after the removal of the left ventricle, right ventricle, left atrium, right atrium of the heart).
S4: and calculating a blood supply coefficient according to the coefficient of the heart volume and the blood flow sum data. The formula is as follows:
Figure BDA0003609155850000091
wherein q is the sum of blood flow (in ml/min, i.e. blood supply per minute) of the left coronary artery and the right coronary artery of the heart, and f is the volume parameter of the heart.
S5: and comparing the blood supply coefficient with a preset coefficient value to obtain the heart blood supply state. If the value is less than the preset coefficient value to a certain extent, the blood supply of the coronary artery of the heart is determined to be suspected to be insufficient or determined to be insufficient.
One example is that the invention uses the heart volume as a heart volume parameter, and the heart weight is calculated by 3D modeling of the measured heart. When the volume of the heart (the volume of the substantial part left after removing the left ventricle, the right ventricle, the left atrium, and the right atrium of the heart) was 240cm3, the coronary blood supply amount was 85ml/min, and the blood supply amount formula was substituted, 0.3542 was calculated, and the preset coefficient value was set to 0.4000 (the preset coefficient value here was obtained with reference to the blood supply amount and the heart volume of several normal hearts), and therefore, the coronary blood supply amount in this example was larger than the preset coefficient value, and it was determined that the coronary blood supply amount was suspected to be insufficient.
Referring to fig. 4, one example of this is that in the coronary blood vessel blood supply amount analysis device, the operation process is as follows:
s1: and pushing a data input interface to the user, and receiving the cross-sectional medical image picture of the heart selected by the user in the input interface.
S2: obtaining blood flow sum data of a left coronary artery and a right coronary artery of the heart;
the method comprises the following steps of obtaining blood flow sum data of a left heart coronary artery and a right heart coronary artery, wherein the specific method comprises the following steps:
the method comprises the steps of inputting blood flow data of a left heart coronary artery and blood flow data of a right heart coronary artery independently, inputting the diameter of a blood vessel of a coronary orifice, and obtaining the blood flow of the right heart coronary artery and the left heart coronary artery respectively through a formula q & ltva & gt, wherein v is blood flow velocity, and a is the cross-sectional area of the blood vessel orifice.
S3: the cardiac volume parameters of the present invention are obtained.
In this example, the volume parameter of the heart is the weight and the substantial volume of the heart, but the means for obtaining the weight and the substantial volume of the heart is effective and the cost is high (for example, the heart volume is calculated by three-dimensional color ultrasound, the heart volume is calculated by three-dimensional radiography, and the weight of the heart can be calculated by the volume and the density of the muscle), which is only an alternative example of the present invention.
S4: and calculating a blood supply coefficient according to the coefficient of the heart volume and the blood flow sum data. The formula is as follows:
Figure BDA0003609155850000101
wherein q is the sum of blood flow (in ml/min, i.e. blood supply per minute) of the left coronary artery and the right coronary artery of the heart, and f is the volume parameter of the heart.
S5: and comparing the blood supply quantity coefficient with a preset coefficient value to obtain the heart blood supply state. If the value is less than the preset coefficient value to a certain extent, the blood supply of the coronary artery of the heart is determined to be suspected to be insufficient or determined to be insufficient.
One example is that the invention uses the heart volume as a heart volume parameter, and the heart weight is calculated by 3D modeling of the measured heart. When the volume of the heart (the volume of the substantial part left after removing the left ventricle, the right ventricle, the left atrium, and the right atrium of the heart) was 240cm3, the coronary blood supply amount was 85ml/min, and the blood supply amount formula was substituted, 0.3542 was calculated, and the preset coefficient value was set to 0.4000 (the preset coefficient value here was obtained with reference to the blood supply amount and the heart volume of several normal hearts), and therefore, the coronary blood supply amount in this example was larger than the preset coefficient value, and it was determined that the coronary blood supply amount was suspected to be insufficient.
The above are exemplary illustrations of the present invention, in which each example is focused on, and in which a complete content is not set forth in a certain example, and the content shown in other examples may be combined. None of the above examples are single examples and new examples may be composed under possible combinations, but the composed new examples must not violate the core idea of the present invention. Moreover, if certain example combinations conflict with and contradict the inventive concepts of this patent, the examples should not be simply combined and adjustments to eliminate conflicts and conflicts should be avoided or made after combination.
It should be noted that the present example is not limited to the only implementation of the present invention, but rather to one or more of the many ways in which the present invention may be implemented. Other solutions obtained without departing from the core idea of the invention fall within the scope of protection of the invention.

Claims (10)

1. Coronary blood supply volume analysis apparatus comprising a processor, a memory having a computer program stored therein, wherein the computer program, when executed by the processor, causes the processor to perform the following operations:
s1: calculating the blood supply coefficient of coronary vessels; the blood supply volume coefficient is obtained by the following formula:
Figure FDA0003609155840000011
in the formula, q is the sum of blood flow of the left coronary artery and the right coronary artery of the heart, and f is the volume parameter of the heart;
s2: judging the blood supply state level of the coronary artery of the heart through the blood supply coefficient, specifically, storing a preset coefficient value in the memory, and comparing the blood supply coefficient with the preset coefficient value to obtain the blood supply state of the heart; the state of blood supply to the heart includes whether the heart is in an ischemic state.
2. The coronary blood supply amount analysis device according to claim 1,
wherein, the blood flow of the right coronary artery and the blood flow of the left coronary artery of the heart are obtained by the following modes:
obtaining the cross-sectional area and the blood flow velocity of the vascular orifice of the right coronary artery and the left coronary artery of the heart respectively through blood flow color ultrasound;
the blood flow of the right coronary artery and the left coronary artery of the heart is obtained by the formula q va, where v is the blood flow velocity and a is the cross-sectional area of the vascular orifice.
3. The coronary blood supply volume analysis device according to claim 1, wherein the volume parameter is one of the following: a heart global volume comprising a heart internal cavity; a volume of a substantial portion of the cardiac body not containing the internal cavity of the heart; a coefficient representing a volume of the heart;
the whole volume of the heart and the substantial part volume of the heart body are obtained by one of three-dimensional radiography calculation, ultrasonic detection and calculation;
wherein the coefficient of the cardiac volume is obtained by the formula:
f＝S.h
in the formula, the area of the maximum cross section of the S heart, and h is the height of the heart.
4. A coronary blood supply analysis apparatus as claimed in claim 3, wherein the area of the largest cross section of the heart is obtained by:
s41: introducing a medical image picture of the cross section of the heart;
s42: receiving calibration performed by a user on a cross-sectional image of the heart, the calibration comprising:
dividing an image belonging to the heart and images belonging to other tissues in a heart cross section picture by a user;
marking images belonging to the heart on the divided medical image picture of the heart cross section;
s43: the area of the heart at the largest cross section of the heart is obtained by performing area calculation on the images belonging to the heart.
5. The coronary blood supply amount analysis device according to claim 4,
the image of the heart cross section is specifically a heart cross section medical image obtained by one of CT, nuclear magnetic resonance and spiral CT, wherein the image belonging to the heart, the image of human muscle tissue and the image of bone lattice are composed of gray and white pixels, and the image belonging to the lung is composed of black pixels;
the calibration performed by the user on the heart cross-sectional image specifically comprises the following steps: dividing an image belonging to the heart from a human muscle tissue image and a bone image by a user by using a black pixel brush; an image belonging to the heart is wrapped by a black pixel connected domain, wherein the black pixel connected domain comprises a lung image and an image formed by a brush.
6. The coronary blood supply amount analysis device according to claim 4,
the medical image picture of the heart cross section is specifically a medical image picture of the heart cross section with the largest cross section area found out from a plurality of medical image pictures of the heart cross section.
7. The coronary blood supply amount analysis device according to claim 4,
the height of the heart is the distance between the apex of the heart and the mouth of the right coronary artery;
the heart height is obtained by one of the ultrasonic image calculations through user input.
8. The operation method of the coronary blood supply analysis and calculation device is realized in a computer system with a processor, a memory storing a computer program and a display screen, and is characterized by comprising the following steps:
pushing a data input interface to a user, and receiving a heart cross section medical image picture selected by the user in the input interface;
obtaining the blood flow sum data of the heart height, the left coronary artery and the right coronary artery of the heart;
pushing a picture editing interface to a user, wherein a heart cross section medical image picture selected by the user and an editing tool are displayed in the editing interface; receiving a user to edit the picture, including: in the picture, the user divides the image belonging to the heart from the images belonging to the remaining tissues; marking images belonging to the heart on the divided medical image picture of the heart cross section; calculating the area of the image belonging to the heart to obtain the heart area at the maximum cross section of the heart;
calculating the coefficient of the heart volume according to the area and the height of the heart; calculating a blood supply coefficient according to the coefficient of the heart volume and the blood flow sum data;
and comparing the blood supply quantity coefficient with a preset coefficient value to obtain the heart blood supply state.
9. The method of claim 8, wherein the step of obtaining the data of the sum of the blood flow of the heart height, the left coronary artery and the right coronary artery comprises one of the following steps:
(1) heart height directly entered by the user in the data entry interface;
(2) the blood flow sum data of the left coronary artery and the right coronary artery of the heart is directly input in the data input interface by a user;
(3) the processor calculates and obtains the sum data according to the blood flow data of the left coronary artery and the blood flow data of the right coronary artery of the heart which are directly input by the user in the data input interface.
10. The method of claim 8, wherein the method of obtaining the heart height comprises:
the user imports the heart ultrasonic image in the data input interface, marks the heart apex and the right coronary artery mouth in the editing interface, and the processor calculates the heart height according to the positions of the heart apex and the right coronary artery mouth marked by the user.
CN202210428598.9A 2022-04-22 2022-04-22 Coronary blood vessel blood supply amount analysis device and operation method Pending CN114882099A (en)

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