CN114870062A - Composite wound dressing and preparation process thereof - Google Patents

Composite wound dressing and preparation process thereof Download PDF

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Publication number
CN114870062A
CN114870062A CN202210539321.3A CN202210539321A CN114870062A CN 114870062 A CN114870062 A CN 114870062A CN 202210539321 A CN202210539321 A CN 202210539321A CN 114870062 A CN114870062 A CN 114870062A
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layer
composite
wound dressing
silica gel
gel composite
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CN202210539321.3A
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CN114870062B (en
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唐海达
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Jiaxing Linhua Medical Material Co ltd
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Jiaxing Linhua Medical Material Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/24Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • A61F13/0203Adhesive plasters or dressings having a fluid handling member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • A61F13/023Adhesive plasters or dressings wound covering film layers without a fluid handling layer
    • A61F13/0233Adhesive plasters or dressings wound covering film layers without a fluid handling layer characterised by the oclusive layer skin contacting layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • A61F13/0276Apparatus or processes for manufacturing adhesive dressings or bandages
    • A61F13/0289Apparatus or processes for manufacturing adhesive dressings or bandages manufacturing of adhesive dressings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/26Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28Polysaccharides or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties

Abstract

The invention discloses a composite wound dressing and a preparation process thereof, wherein the composite wound dressing comprises a release layer, a silica gel composite layer, an intermediate layer and a substrate layer, a cavity is formed between the silica gel composite layer and the substrate layer, the intermediate layer is arranged in the cavity, the silica gel composite layer is provided with a window, and the size of the window is smaller than that of the intermediate layer; the silicone gel composite layer sequentially comprises silicone gel, a polyurethane film and polyacrylate adhesive from top to bottom, the middle layer sequentially comprises a contact layer, a first bonding layer and a moisture absorption layer from top to bottom, and the base material layer sequentially comprises a second bonding layer and a waterproof breathable layer from top to bottom; the silicone gel composite layer and the second bonding layer are both provided with through holes. According to the composite wound dressing and the preparation process thereof, the base material layer is attached to the silica gel composite layer, the middle layer is wrapped in the middle layer and is firmly fixed, the dressing is prevented from layering and falling off, the energy consumption is low, the production efficiency is higher, and the liquid absorption capacity of a product is greatly improved. Meanwhile, the dressing blocks water and bacteria, and the clinical operation is simpler and more convenient.

Description

Composite wound dressing and preparation process thereof
Technical Field
The invention relates to the technical field of medical dressings, in particular to a composite wound dressing and a preparation process thereof.
Background
Patent publication No. CN 103655046 a describes a wound dressing having a three-layer structure and a method for producing the same, the wound dressing having a wound contact layer, an intermediate moisture-absorbing layer, and an outer layer, the wound contact layer being a nonwoven fabric comprising hydrophilic fibers and hydrophobic fibers, the intermediate moisture-absorbing layer being a nonwoven fabric comprising another set of hydrophilic fibers and hydrophobic fibers, and the outer layer being a nonwoven fabric comprising hydrophobic fibers. The wound contact layer contains hydrophobic fibers, and the hydrophobic fibers are not capable of absorbing moisture, so that the hydrophobic fibers are easy to adhere to wound tissues after contacting the wound for a long time, and secondary injury and pain of the wound are easily caused when the wound dressing is uncovered. The middle moisture absorption layer is made of another group of hydrophilic fiber and hydrophobic fiber; the fiber has high hardness and no elasticity, and can cause wound discomfort of patients after being applied for a long time. The outer layer is hydrophobic fiber non-woven fabric, does not have the performance of water and bacteria resistance, and is easy to invade by microorganisms to cause wound infection. And this dressing does not have the self-adhesion function, need use the secondary to have the dressing of stickness to paste fixedly, has increased the quantity of medical consumables, brings the inconvenient operation. The liquid absorption amount of the dressing is 30-50 g/square meter, and for a wound surface with large liquid seepage amount, the liquid absorption amount needs to be improved.
Also introduces a preparation method of the dressing: the adhesive is prepared by preparing each layer in a hot melting mode, a needling mode or a spunlace mode and a chemical bonding agent mode, adding bi-component fibers, and compounding the layers together in the hot melting mode, the needling mode or the spunlace mode and the chemical bonding agent mode, wherein the adhesive strength is not high. After the dressing prepared by the method absorbs moisture or wound seepage, the peel strength between the contact layer and the moisture absorption layer is 0.2-0.6N/cm, the bonding strength between the moisture absorption layer and the outer layer is 0.05-0.2N/cm, the bonding strength between the layers is not high, and the layers are easy to delaminate and fall off.
Based on the situation, the invention provides a composite wound dressing and a preparation process thereof, which can effectively solve the problems.
Disclosure of Invention
The invention aims to provide a composite wound dressing and a preparation process thereof. The composite wound dressing and the preparation process thereof are convenient to use, the middle layer is wrapped in the middle layer by the laminating of the substrate layer and the silica gel composite layer and is firmly fixed, the dressing is prevented from layering and falling off, the energy consumption is low, the production efficiency is higher, and the liquid absorption capacity of the product is greatly improved. Meanwhile, the dressing resists water and bacteria, has self-adhesion, good application performance and simpler and more convenient clinical operation.
The invention is realized by the following technical scheme:
a composite wound dressing comprises a release layer, a silica gel composite layer, an intermediate layer and a substrate layer, wherein a cavity is formed between the silica gel composite layer and the substrate layer, the intermediate layer is arranged in the cavity, the silica gel composite layer is provided with a window, and the size of the window is smaller than that of the intermediate layer;
the silicone gel composite bed includes silicone gel, polyurethane film and polyacrylate glue from top to bottom in proper order, the intermediate level includes contact layer, first tie coat and moisture absorption layer from top to bottom in proper order, the substrate layer includes second tie coat and waterproof ventilative layer from top to bottom in proper order.
The invention aims to provide a composite wound dressing and a preparation process thereof. The composite wound dressing and the preparation process thereof are convenient to use, the middle layer is wrapped in the middle layer by the laminating of the substrate layer and the silica gel composite layer and is firmly fixed, the dressing is prevented from layering and falling off, the energy consumption is low, the production efficiency is higher, and the liquid absorption capacity of the product is greatly improved. Meanwhile, the dressing resists water and bacteria, has self-adhesion, good application performance and simpler and more convenient clinical operation.
Preferably, the silicone gel composite layer and the second bonding layer are both provided with through holes.
Preferably, the contact layer is gel fiber non-woven fabric, the moisture absorption layer is polyurethane foam or polyvinyl alcohol foam, the waterproof breathable layer is a polyurethane film or polyurethane elastic non-woven fabric, the first bonding layer is a hot melt adhesive net film or a dot film, and the second bonding layer is pressure-sensitive adhesive.
Preferably, the gel fiber non-woven fabric is made of one or more of alginate fibers, modified cellulose fibers, modified chitosan fibers and polyvinyl alcohol fibers.
Preferably, the gram weight of the gel fiber non-woven fabric is 80-180 g/m 2 The thickness is 1.0-5.0 mm, and the gram weight of the first bonding layer is 8-50 g/m 2 And the thickness of the moisture absorption layer is 2-5 mm.
Preferably, the thickness of the waterproof breathable layer is 10-150 mu m, and the gram weight of the pressure-sensitive adhesive is 10-40 g/m 2
Preferably, the thickness of the polyurethane film is 10-40 mu m, and the gram weight of the silicon gel is 30-300 g/m 2 The gram weight of the polyacrylate adhesive is 10-40 g/m 2
Preferably, the shape of the through hole is circular, rhombic or polygonal.
Preferably, the release layer comprises a first release film and a second release film, wherein a bent part is arranged at one end of the first release film close to the middle of the wound dressing, and the second release film partially covers the first bent part of the first release film.
A preparation process of a composite wound dressing comprises the following steps:
step S1: unwinding and flatly paving the contact layer, the first bonding layer and the moisture absorption layer, and putting the contact layer, the first bonding layer and the moisture absorption layer into a tentering and shaping oven for shaping, wherein the temperature of the oven is 90-200 ℃, the drying time is 10-600 s, and the material feeding speed is 1-10 m/min;
step S2: rapidly pressing the materials by two compression rollers, and cooling and shaping at room temperature to prepare the composite coiled material;
step S3: respectively unwinding the substrate layer, the composite coiled material, the silica gel composite layer and the release layer in multi-station dressing equipment;
step S4: the composite coiled material is cut into sheets through a first cutter after being uncoiled and is attached to the pressure-sensitive adhesive of the uncoiled base material layer;
step S5: unwinding the silica gel composite layer, wherein one side of the polyacrylate adhesive faces to the pressure-sensitive adhesive position of the substrate layer, and attaching the edges;
step S6: a window is arranged in the middle of the silica gel composite layer through a second cutter;
step S7: the three materials of the base material layer, the composite coiled material and the silica gel composite layer are pressed by a press roller, so that the three materials are closely adhered and compounded;
step S8: and compounding a release layer at the silicone gel position of the silicone gel composite layer, and cutting and molding by a molding knife die.
Compared with the prior art, the invention has the following advantages and beneficial effects:
the composite wound dressing and the preparation process thereof are convenient to use, the middle layer is wrapped in the middle layer by the laminating of the substrate layer and the silica gel composite layer and is firmly fixed, the dressing is prevented from layering and falling off, the energy consumption is low, the production efficiency is higher, and the liquid absorption capacity of the product is greatly improved. Meanwhile, the dressing resists water and bacteria, has self-adhesion, good application performance and simpler and more convenient clinical operation.
Drawings
FIG. 1 is a schematic structural view of a composite wound dressing according to the present invention;
FIG. 2 is a schematic flow chart of a first part of the preparation process of the present invention;
FIG. 3 is a schematic flow chart of a second part of the preparation process of the present invention.
Detailed Description
In order that those skilled in the art will better understand the technical solutions of the present invention, the following description of the preferred embodiments of the present invention is provided in conjunction with specific examples, but it should be understood that the drawings are for illustrative purposes only and should not be construed as limiting the patent; for the purpose of better illustrating the embodiments, certain features of the drawings may be omitted, enlarged or reduced, and do not represent the size of an actual product; it will be understood by those skilled in the art that certain well-known structures in the drawings and descriptions thereof may be omitted. The positional relationships depicted in the drawings are for illustrative purposes only and are not to be construed as limiting the present patent.
Example 1:
as shown in fig. 1 to 3, the invention provides a composite wound dressing, which comprises a release layer 1, a silicone gel composite layer 13, a middle layer and a substrate layer 14, wherein a cavity is formed between the silicone gel composite layer 13 and the substrate layer 14, the middle layer is arranged in the cavity, the silicone gel composite layer 13 is provided with a window, and the size of the window is smaller than that of the middle layer;
the silicone gel composite layer 13 sequentially comprises a silicone gel 2, a polyurethane film 3 and a polyacrylate adhesive 4 from top to bottom, the middle layer sequentially comprises a contact layer 5, a first bonding layer 6 and a moisture absorption layer 7 from top to bottom, and the base material layer 14 sequentially comprises a second bonding layer 8 and a waterproof breathable layer 9 from top to bottom.
Further, in another embodiment, the silicone gel composite layer 13 and the second adhesive layer 8 are both provided with through holes.
Further, in another embodiment, the contact layer 5 is a gel fiber non-woven fabric, the moisture absorption layer 7 is a polyurethane foam or a polyvinyl alcohol foam, the waterproof breathable layer 9 is a polyurethane film 3 or a polyurethane elastic non-woven fabric, the first adhesive layer 6 is a hot melt adhesive net film or a dot film, and the second adhesive layer 8 is a pressure sensitive adhesive.
The polyurethane foam or polyvinyl alcohol foam is soft and elastic, does not press wounds, and can prevent pressure sores and bedsores; the polyurethane film 3 not only has the functions of water resistance and bacteria resistance, greatly reduces the pollution, infection and inflammation of microorganisms of wounds, but also has extremely high water vapor transmission rate which is more than 2000g/(24h × m) 2 );
Further, in another embodiment, the gel fiber non-woven fabric is made of one or more of alginate fibers, modified cellulose fibers, modified chitosan fibers and polyvinyl alcohol fibers.
Further, in another embodiment, the gram weight of the gel fiber non-woven fabric is 80-180 g/m 2 The thickness is 1.0-5.0 mm, and the gram weight of the first bonding layer 6 is 8-50 g/m 2 The thickness of the moisture absorption layer 7 is 2-5 mm.
Further, in another embodiment, the thickness of the waterproof breathable layer 9 is 10-150 μm, and the gram weight of the pressure-sensitive adhesive is 10-40 g/m 2
Further, in another embodiment, the thickness of the polyurethane film 3 is 10 to 40 μm, and the gram weight of the silicone gel 2 is 30 to 300g/m 2 The gram weight of the polyacrylate adhesive 4 is 10-40 g/m 2
Further, in another embodiment, the shape of the through hole is circular, diamond-shaped or polygonal.
Further, in another embodiment, the release layer 1 includes a first release film 15 and a second release film 16, a bending portion 151 is disposed at one end of the first release film 15 near the middle of the wound dressing, and the second release film 16 partially covers the bending portion 151 of the first release film 15.
Due to the structure, the release layer is convenient for a user to tear down.
According to another aspect of the invention, a preparation process of the composite wound dressing is provided, which comprises the following steps:
step S1: unwinding and flatly paving the contact layer 5, the first bonding layer 6 and the moisture absorption layer 7, and enabling the contact layer, the first bonding layer and the moisture absorption layer to enter a tentering and shaping oven 10 for shaping, wherein the temperature of the oven is 90-200 ℃, the drying time is 10-600 s, and the material entering speed is 1-10 m/min;
step S2: rapidly pressing the materials by two compression rollers 11, and cooling and shaping at room temperature to prepare a composite coiled material 12;
step S3: respectively unwinding the substrate layer 14, the composite coiled material 12, the silicone gel composite layer 13 and the release layer 1 in multi-station dressing equipment;
step S4: the composite coiled material 12 is unwound and then cut into sheets by a first cutter 17, and the sheets are attached to the pressure-sensitive adhesive of the unwound substrate layer 14;
step S5: unwinding the silicone gel composite layer 13, wherein one side of the polyacrylate adhesive 4 faces to the pressure-sensitive adhesive position of the substrate layer 14, and attaching the edges;
step S6: the silicone gel composite layer 13 is provided with a window in the middle through a second cutter 18;
step S7: the three materials of the substrate layer 14, the composite coiled material and the silicone gel composite layer 13 are pressed by a press roller 11, so that the three materials are tightly adhered and compounded;
step S8: and compounding a release layer 1 at the silicone gel 2 of the silicone gel composite layer 13, and cutting and molding by a molding knife die 19.
The composite wound dressing disclosed by the invention has elasticity, has a self-adhesive function, is not adhered to a wound, and is comfortable to wear by a patient. The outer layer has the performance of water and bacteria resistance, thereby preventing wound infection and simplifying nurse operation. The liquid absorption amount of the dressing is more than 40 g/square meter, the dressing can permanently absorb seepage, and the service life can be as long as 7 days.
After absorbing moisture or absorbing wound exudate, the peel strength between the contact layer 5 and the moisture absorption layer 7 after absorbing moisture is greater than 0.6N/cm, the bonding strength between the moisture absorption layer 7 and the outer layer is greater than 0.2N/cm, the composite dressing has higher liquid absorption amount than a common composite dressing, the bonding strength between the layers is high, and the composite dressing is not easy to delaminate and fall off.
According to the description and the drawings, the composite wound dressing and the preparation process thereof can be easily manufactured or used by the person skilled in the art, and the positive effects recorded in the invention can be generated.
Unless otherwise specified, in the present invention, if there is an orientation or positional relationship indicated by terms of "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., based on the orientation or positional relationship shown in the drawings, it is only for convenience of describing the present invention and simplifying the description, rather than to indicate or imply that the device or element so referred to must have a particular orientation, be constructed and operated in a particular orientation, therefore, the terms describing orientation or positional relationship in the present invention are for illustrative purposes only, and should not be construed as limiting the present patent, specific meanings of the above terms can be understood by those of ordinary skill in the art in light of the specific circumstances in conjunction with the accompanying drawings.
Unless expressly stated or limited otherwise, the terms "disposed," "connected," and "connected" are used broadly and encompass, for example, being fixedly connected, detachably connected, or integrally connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in any way, and all simple modifications and equivalent variations of the above embodiments according to the technical spirit of the present invention are included in the scope of the present invention.

Claims (10)

1. A composite wound dressing characterized by: the solar cell comprises a release layer, a silicon gel composite layer, an intermediate layer and a substrate layer, wherein a cavity is formed between the silicon gel composite layer and the substrate layer, the intermediate layer is arranged in the cavity, the silicon gel composite layer is provided with a window, and the size of the window is smaller than that of the intermediate layer;
the silicone gel composite bed includes silicone gel, polyurethane film and polyacrylate glue from top to bottom in proper order, the intermediate level includes contact layer, first tie coat and moisture absorption layer from top to bottom in proper order, the substrate layer includes second tie coat and waterproof ventilative layer from top to bottom in proper order.
2. Composite wound dressing according to claim 1, characterized in that: the contact layer is gel fiber non-woven fabric, the moisture absorption layer is polyurethane foam or polyvinyl alcohol foam, the waterproof breathable layer is a polyurethane film or polyurethane elastic non-woven fabric, the first bonding layer is a hot melt adhesive net film or a dot film, and the second bonding layer is pressure-sensitive adhesive.
3. Composite wound dressing according to claim 2, characterized in that: the gel fiber non-woven fabric is made of one or more of alginate fibers, modified cellulose fibers, modified chitosan fibers and polyvinyl alcohol fibers.
4. Composite wound dressing according to claim 2, characterized in that: the gram weight of the gel fiber non-woven fabric is 80-180 g/m 2 The thickness is 1.0-5.0 mm, and the gram weight of the first bonding layer is 8-50 g/m 2 And the thickness of the moisture absorption layer is 2-5 mm.
5. According to the rightThe composite wound dressing of claim 1, wherein: the thickness of the waterproof breathable layer is 10-150 mu m, and the gram weight of the pressure-sensitive adhesive is 10-40 g/m 2
6. Composite wound dressing according to claim 1, characterized in that: the thickness of the polyurethane film is 10-40 mu m, and the gram weight of the silicon gel is 30-300 g/m 2 The gram weight of the polyacrylate adhesive is 10-40 g/m 2
7. Composite wound dressing according to claim 1, characterized in that: the shape of the through hole is round, diamond or polygon.
8. Composite wound dressing according to claim 1, characterized in that: from the type layer including first from type membrane and second from the type membrane, first from the type membrane be close to wound dressing middle one end and be equipped with the kink, the second from type membrane part cover on first kink from the type membrane.
9. Composite wound dressing according to claim 1, characterized in that: through holes are formed in the silicon gel composite layer and the second bonding layer.
10. A process for the preparation of a composite wound dressing according to any of claims 1 to 7, characterized in that: the method comprises the following steps:
step S1: unwinding and flatly paving the contact layer, the first bonding layer and the moisture absorption layer, and putting the contact layer, the first bonding layer and the moisture absorption layer into a tentering and shaping oven for shaping, wherein the temperature of the oven is 90-200 ℃, the drying time is 10-600 s, and the material feeding speed is 1-10 m/min;
step S2: rapidly pressing the materials by two compression rollers, and cooling and shaping at room temperature to prepare the composite coiled material;
step S3: respectively unwinding the substrate layer, the composite coiled material, the silica gel composite layer and the release layer in multi-station dressing equipment;
step S4: the composite coiled material is cut into sheets through a first cutter after being uncoiled and is attached to the pressure-sensitive adhesive of the uncoiled base material layer;
step S5: unwinding the silica gel composite layer, wherein one side of the polyacrylate adhesive faces to the pressure-sensitive adhesive position of the substrate layer, and attaching the edges;
step S6: a window is arranged in the middle of the silica gel composite layer through a second cutter;
step S7: the three materials of the base material layer, the composite coiled material and the silica gel composite layer are pressed by a press roller, so that the three materials are closely adhered and compounded;
step S8: and compounding two release layers at the silicone gel position of the silicone gel composite layer, and cutting and molding by a molding knife die.
CN202210539321.3A 2022-05-17 2022-05-17 Composite wound dressing and preparation process thereof Active CN114870062B (en)

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