CN114869389B - Intra-tumor stent for intracranial aneurysm - Google Patents
Intra-tumor stent for intracranial aneurysm Download PDFInfo
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- CN114869389B CN114869389B CN202210528895.0A CN202210528895A CN114869389B CN 114869389 B CN114869389 B CN 114869389B CN 202210528895 A CN202210528895 A CN 202210528895A CN 114869389 B CN114869389 B CN 114869389B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/12031—Type of occlusion complete occlusion
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
- A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
- A61B17/12118—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm for positioning in conjunction with a stent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
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Abstract
The invention provides an intratumoral stent for intracranial aneurysm, which comprises a stent body and a ligation sleeve, wherein the stent body is of a net structure and is provided with a bottom and a top which are opposite, the bottom of the stent body is fixedly connected with the ligation sleeve, a abdicating hole is formed in the position, adjacent to the ligation sleeve, of the stent body, and the size of the abdicating hole is larger than the radial size of a micro catheter for conveying a spring ring. The technical scheme of the invention can ensure that the microcatheter for conveying the spring ring can smoothly pass through the abdicating hole at the bottom of the stent body and convey the spring ring into the aneurysm, thereby improving the operability of the operation.
Description
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to an intratumoral stent for intracranial aneurysm.
Background
Intracranial aneurysm is the most important disease of hemorrhagic cerebrovascular disease, because the local vessel wall of intracranial artery is damaged by the acquired injury or congenital dysplasia and other factors, under the influence of the load of blood flow power or other factors, the intracranial aneurysm gradually expands to form abnormal bulge. At present, intracranial aneurysm is mainly treated by an intravascular interventional therapy mode, and the intracranial aneurysm treatment device comprises a spring coil embolism, a support auxiliary spring coil embolism, a blood flow guiding device and an intratumoral turbulent flow device.
In the prior art, an intratumoral stent of an intracranial aneurysm is designed to be woven into a barrel shape, a spherical shape or a hemispherical shape by a plurality of net wires, wherein most of the bottoms of the hemispherical stent are woven with dense grids, the stent is implanted into the aneurysm and needs to pass through a microcatheter through the meshes of the stent, and the aneurysm is filled by releasing a spring ring through the microcatheter. However, since only the dense mesh portion of the stent bottom is exposed after the stent is implanted in the aneurysm, it causes great difficulty in the crossing of the microcatheter.
Therefore, there is a need to provide an improved solution to the above-mentioned deficiencies of the prior art.
Disclosure of Invention
The invention aims to provide an intra-tumor stent for intracranial aneurysm, which solves the problem that a microcatheter for delivering a spring ring in the prior art is difficult to pass through meshes of the stent.
In order to achieve the above purpose, the invention provides the following technical scheme:
an intratumoral stent for an intracranial aneurysm comprises a stent body and a bundling sleeve, wherein the stent body is of a net structure and is provided with a bottom and a top which are opposite, the bottom of the stent body is fixedly connected with the bundling sleeve, a abdicating hole is formed in the position, adjacent to the bundling sleeve, of the stent body, and the size of the abdicating hole is larger than the radial size of a microcatheter for conveying a spring ring.
The intratumoral stent of an intracranial aneurysm as described above, optionally the stent body is disc-shaped in a self-expanded state, the outer diameter of the stent body in the self-expanded state being greater than the inner diameter of the intracranial aneurysm.
The intratumoral stent of an intracranial aneurysm as described above, optionally, the ligation sheath is located at a central position of the stent body, and the abduction hole is disposed adjacent to the central position of the stent body.
Optionally, the yielding holes are provided in a plurality and are distributed at intervals along the circumferential direction of the ligation sleeve.
The intratumoral stent of an intracranial aneurysm as described above, optionally, the ligation sheath is located at an eccentric position of the stent body, and the abduction hole is located at a central position of the stent body.
An intratumoral stent for an intracranial aneurysm as described above, optionally with a visualization ring at the abduction aperture.
The intratumoral stent of an intracranial aneurysm as described above, optionally the size of the abduction holes is greater than the size of the top mesh of the stent body and less than the size of the neck of the aneurysm of the intracranial aneurysm.
The intratumoral stent of an intracranial aneurysm as described above, optionally the shape of the abduction hole is circular, rhombic or elliptical; and defining the diameter of the inner circle of the abdicating hole as the size of the abdicating hole, wherein the diameter of the inner circle of the abdicating hole is 0.6-4mm.
The intratumoral stent of an intracranial aneurysm as described above, optionally the shape of the top mesh of the stent body is circular, diamond or oval; the diameter of an inscribed circle of the top mesh of the stent body is defined as the size of the top mesh, and the diameter of the inscribed circle of the top mesh of the stent body is 0.2-1mm.
Optionally, the stent body is a single-layer mesh structure woven by nickel-titanium wires, platinum-containing nickel-titanium wires, tungsten-containing nickel-titanium wires or tantalum-containing nickel-titanium wires.
Has the advantages that:
the invention relates to an intra-tumor stent of intracranial aneurysm, which comprises a stent body and a pricking sleeve, wherein the stent body is of a net structure and is provided with a bottom and a top which are opposite, the bottom of the stent body is fixedly connected with the pricking sleeve, a abdicating hole is formed in the position, adjacent to the pricking sleeve, of the stent body, and the size of the abdicating hole is larger than the radial size of a micro catheter for conveying a spring ring. Due to the structural design, after the intra-tumor stent is implanted into the intracranial aneurysm, the stent body covers the position of the neck of the aneurysm in the aneurysm, the top of the stent body is attached to the inner wall of the aneurysm sac, and the bottom, the pricking sleeve and the abdicating hole are all positioned at the neck of the aneurysm, so that the micro-catheter for conveying the spring ring can smoothly penetrate through the abdicating hole at the bottom of the stent body and convey the spring ring to the aneurysm, and the operability of the operation is improved. In addition, the intratumoral stent is implanted into the aneurysm, so that the influence on the normal parent artery can be effectively reduced. Meanwhile, the intratumoral stent assists in the embolism to prevent the spring ring from falling off to the parent artery effectively, so that the incidence rate of parent artery thrombus is reduced, the occupation of the intratumoral spring ring can effectively avoid the intratumoral stent from moving to the top of the aneurysm, and the embolism effect is stable and reliable.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate exemplary embodiments of the invention and together with the description serve to explain the invention and not to limit the invention. Wherein:
FIG. 1 is a schematic structural view of a view angle of an intratumoral stent of an intracranial aneurysm according to one embodiment of the invention;
FIG. 2 is a schematic structural view of another perspective of an intratumoral stent of the intracranial aneurysm of FIG. 1;
FIG. 3 is a schematic structural view of an intratumoral stent of the intracranial aneurysm of FIG. 1 from yet another perspective;
FIG. 4 is a schematic structural view of an intratumoral stent of the intracranial aneurysm of FIG. 1 positioned within the intracranial aneurysm;
FIG. 5 is a schematic view of an intratumoral stent and coil for use in conjunction with the intracranial aneurysm of FIG. 1;
FIG. 6 is a schematic structural view of a view angle of an intratumoral stent of an intracranial aneurysm according to another embodiment of the invention;
FIG. 7 is a structural schematic diagram of another perspective of an intratumoral stent of the intracranial aneurysm of FIG. 6;
FIG. 8 is a schematic structural view of the intratumoral stent of the intracranial aneurysm of FIG. 6 positioned within the intracranial aneurysm;
fig. 9 is a schematic illustration of an intratumoral stent and coil used in conjunction with the intracranial aneurysm of fig. 6.
Reference numbers in the figures: 1-a stent body; 11-bottom; 12-top; 13-abdicating holes; 2-bundling the sleeve; 3-spring ring; 4-a microcatheter; 5-conveying pipe; 6-aneurysm.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments that can be derived by one of ordinary skill in the art from the embodiments given herein are intended to be within the scope of the present invention.
The present invention will be described in detail with reference to examples. It should be noted that the embodiments and features of the embodiments may be combined with each other without conflict.
Aiming at the problem that a microcatheter for conveying a spring ring in the prior art is difficult to penetrate through meshes of a stent, the invention provides an intratumoral stent for intracranial aneurysm, which can ensure that the microcatheter for conveying the spring ring can smoothly penetrate through an abdicating hole at the bottom of a stent body and convey the spring ring into the aneurysm.
As shown in fig. 1 to 9, the intratumoral stent for an intracranial aneurysm 6 of the invention comprises a stent body 1 and a ligation sleeve 2, wherein the stent body 1 is of a mesh structure and has a bottom 11 and a top 12 which are opposite, the bottom 11 of the stent body 1 is fixedly connected to the ligation sleeve 2, the stent body 1 is formed with an abdicating hole 13 adjacent to the ligation sleeve 2, and the size of the abdicating hole 13 (defined as the diameter of an inscribed circle of the abdicating hole 13) is larger than the radial size of a microcatheter 4 for delivering a coil 3 (the microcatheter 4 can be selected as a circular tube, and the radial size of the microcatheter 4 is the outer diameter of the microcatheter 4). By the structural design, after the intratumoral stent is implanted into an intracranial aneurysm 6, the stent body 1 covers the position of a neck of the aneurysm 6, the top 12 of the stent body is attached to the inner wall of a tumor sac, and the bottom 11, the pricking sleeve 2 and the abdicating hole 13 of the stent body are all positioned at the neck of the aneurysm, so that the micro-catheter 4 for conveying the spring ring 3 can smoothly pass through the abdicating hole 13 at the bottom 11 of the stent body 1 and convey the spring ring 3 into the aneurysm 6, and the operability of the operation is improved. In addition, the intratumoral stent is implanted into the aneurysm 6, so that the influence on the normal parent artery can be effectively reduced. Meanwhile, the coil spring 3 embolism assisting in the intratumoral stent can effectively prevent the coil spring 3 from falling off to the parent artery, so that the incidence rate of parent artery thrombus is reduced, the occupation of the coil spring 3 in the parent artery can effectively avoid the intratumoral stent from moving to the top of the aneurysm 6, and the embolism effect is stable and reliable.
It should be noted that the ligation sleeve 2 is located at the bottom 11 of the stent body 1, the specific position of the ligation sleeve is not limited, the abdication hole 13 is arranged adjacent to the ligation sleeve 2, the specific position of the abdication hole is not limited, and the ligation sleeve 2 and the abdication hole 13 are located at the neck of the aneurysm after the intratumoral stent is implanted into the intracranial aneurysm 6, which is within the protection scope of the present invention.
Alternatively, if a 0.017in microcatheter is used for the microcatheter 4 delivering the coils 3, the size of the relief holes 13 is slightly larger than the radial size of the microcatheter 4 so that the microcatheter 4 can smoothly pass through the relief holes 13.
When the intratumoral stent is manufactured specifically, the binding sleeve 2 can be of an annular structure, a stent body 1 is obtained by heat treatment and molding after a plurality of braided wires are bound, and all the braided wires are fixed in the binding sleeve 2. The number of the braided wires can be 24, 36, 64, 72, 96, 128 or 144. The material of the binding sleeve 2 can be stainless steel or visible platinum-iridium alloy, and the stent body 1 is a single-layer mesh structure woven by nickel-titanium wires (with super elasticity), platinum-containing nickel-titanium wires, tungsten-containing nickel-titanium wires or tantalum-containing nickel-titanium wires (with visibility). The intratumoral stent has good flexibility, and after the intratumoral stent is implanted into the intracranial aneurysm 6, the top 12 of the stent body 1 can be better attached to the inner wall of a tumor sac.
The stent body 1 of the present invention is disk-shaped in a self-expanded state, and the outer diameter (D) of the stent body 1 in the self-expanded state 1 ) Greater than the inner diameter (D) of the intracranial aneurysm 6. Due to the structural design, after the intratumoral stent is implanted into the intracranial aneurysm 6, the stent body 1 can fully cover the neck part of the aneurysm in the aneurysm 6, so that the spring ring 3 is effectively prevented from falling off to the parent artery, and the thrombus incidence rate of the parent artery is reduced.
In an alternative embodiment of the invention, a developing ring is arranged at the position-avoiding hole 13. The specific mode of the developing ring is to select the woven material forming the relief holes 13 as the developing material, or to provide marks on the woven material forming the relief holes 13. The arrangement of the developing ring can enable an operator to clearly see the specific position of the abdicating hole 13, so that the micro-catheter 4 for conveying the spring coil 3 can rapidly and smoothly pass through the abdicating hole 13 and convey the spring coil 3 to the aneurysm 6, and the operability of the operation is further improved.
In an alternative embodiment of the invention, the stent body 1 has an outer diameter (D) in a self-expanded state 1 ) 3-20mm (e.g., 3mm, 5mm, 10mm, 15mm, 20mm, and any interval therebetween).
In an alternative embodiment of the present invention, the stent body 1 has a height (H) in a self-expanding state 1 ) Is its outer diameter (D) 1 ) 10-20% (e.g., 10%, 12%, 14%, 16%, 18%, 20%, and the interval between any two endpoints).
As shown in fig. 1 to 5, in an embodiment of the present invention, the ligation cover 2 is located at a central position of the stent body 1, and the abdicating hole 13 is arranged adjacent to the central position of the stent body 1. Due to the structural design, the micro catheter 4 for conveying the spring ring 3 can smoothly enter the aneurysm 6, and the operability of the operation is improved.
Optionally, the yielding holes 13 are provided in a plurality, and the plurality of yielding holes 13 are distributed at intervals along the circumferential direction of the bundling sleeve 2. The number of the abdicating holes 13 can be 2, 3 or more than 3, so that the structure design can more conveniently ensure that the micro-catheter 4 for delivering the spring ring 3 can more smoothly enter the aneurysm 6, and the operability of the operation is more effectively improved.
In the embodiment of the invention, the ligation sleeve 2 is arranged at the center of the bottom 11 of the stent body 1, the number of the abdicating holes 13 is four, and the four abdicating holes 13 are respectively positioned in four directions of the ligation sleeve 2 and are all adjacent to the ligation sleeve 2, so that the micro-catheter 4 for conveying the spring ring 3 can smoothly pass through any abdicating hole 13 at the bottom 11 of the stent body 1 and convey the spring ring 3 into the aneurysm 6, and the operability of the operation is improved.
In this embodiment, the abdicating hole 13 may be circular, diamond-shaped or oval.
As shown in fig. 2, the diameter of the inscribed circle of the abdicating hole 13 is defined as D 3 (i.e. the size of the abdication hole 13), the diameter of the inscribed circle of the mesh hole at the top 12 of the stent body 1 is D 2 (i.e., the size of the apical 12-mesh opening), the diameter of the inscribed circle of the neck opening of the intracranial aneurysm 6 is D 4 (size of the neck of the tumor), the size of the abduction hole 13 is larger than the size of the mesh of the top 12 of the stent body 1 and smaller than the size of the neck of the intracranial aneurysm 6. With such a structural design, the stent body 1 of the present embodiment has a dense mesh at the top 12 and a large abdicating hole 13 at the bottom 11 for the micro-catheter 4 for delivering the spring coil 3 to pass through smoothly.
In this embodiment, the diameter D of the inscribed circle of the abdicating hole 13 3 Is 0.6-4mm (0.6 mm, 1mm, 1.5mm, 2mm, 2.5mm, 3mm, 3.5mm, 4mm and the interval between any two endpoints). Diameter D of inscribed circle of top 12 meshes of stent body 1 2 Is 0.2-1mm (0.2 mm, 0.4mm, 0.6mm, 0.8mm, 1mm and any two end points)Interval values between values).
As shown in fig. 5, the intratumoral stent of the present embodiment is used in cooperation with a coil 3 for embolization of a wide-necked bifurcated aneurysm as follows: firstly, an intratumoral stent is conveyed into an aneurysm 6 through a conveying pipe 5, depending on the flexibility of a braided wire, a 12-mesh structure at the top of a stent body 1 can be attached to the wall of the aneurysm 6, 11 four abdicating holes 13 at the bottom of the stent body 1 are all positioned at the position of a neck of the aneurysm, then a micro-catheter 4 for conveying a spring ring 3 can smoothly enter the aneurysm 6 through any abdicating hole 13 at the bottom of the stent body 1, the aneurysm 6 is filled by releasing the spring ring 3 through the micro-catheter 4, the spring ring 3 is released after being filled, then the micro-catheter 4 for conveying the spring ring 3 is withdrawn, the position of the intratumoral stent is adjusted through the conveying pipe 5, the stent is released after the position of the stent is properly adjusted, and finally the conveying pipe 5 for conveying the intratumoral stent is withdrawn.
In another embodiment of the present invention, as shown in fig. 6 to 9, the ligation cover 2 is located at an eccentric position of the stent body 1, and the abdicating hole 13 is located at a central position of the stent body 1. Due to the structural design, the microcatheter 4 for delivering the coil spring 3 can smoothly pass through the abdicating hole 13 in the center of the bottom 11 of the stent body 1 and deliver the coil spring 3 into the aneurysm 6, and the operability of the operation is improved.
In this embodiment, the yielding hole 13 at the central position of the stent body 1 can be circular or elliptical.
As shown in FIGS. 6 and 8, in the present embodiment, the stent body 1 has an outer diameter D in a self-expanded state 5 The diameter of the inscribed circle of the abdicating hole 13 is D 6 (i.e. the size of the abdication hole 13), the diameter of the inscribed circle of the mesh hole at the top 12 of the stent body 1 is D 7 (i.e., the size of the apical 12-mesh opening), the radial dimension of the intracranial aneurysm 6 is D 8 And the diameter of the inscribed circle of the neck of the intracranial aneurysm 6 is D 9 (i.e., the size of the neck opening), the outer diameter D of the stent body 1 in the self-expanding state 5 Greater than size D of intracranial aneurysm 6 8 The size of the abduction hole 13 is larger than the size of the mesh hole of the top 12 of the stent body 1 and smaller than the size of the neck opening of the intracranial aneurysm 6. The bracket of the embodiment is designed in such a wayThe body 1 has a dense mesh top 12 and a large relief hole 13 at the bottom 11 for the micro-tube 4 carrying the spring coil 3 to pass through smoothly.
In this embodiment, the dimension D of the abdicating hole 13 6 And is 0.6-4mm (0.6 mm, 1mm, 1.5mm, 2mm, 2.5mm, 3mm, 3.5mm, 4mm, and intervals between any two endpoints). Diameter D of inscribed circle of top 12 meshes of stent body 1 7 And is 0.2-1mm (0.2 mm, 0.4mm, 0.6mm, 0.8mm, 1mm, and any interval between two endpoints).
As shown in fig. 9, the intratumoral stent of the present embodiment is used in cooperation with a coil 3 in embolization of a wide-necked bifurcated aneurysm 6 as follows: firstly, conveying the intratumoral stent into an aneurysm 6 through a conveying pipe 5, depending on the flexibility of a braided wire, enabling a 12-mesh structure at the top of a stent body 1 to be attached to the wall of the aneurysm 6, enabling abdicating holes 13 in the center of the bottom 11 of the stent body 1 to be located at the position of a neck of the aneurysm, enabling a micro-catheter 4 for conveying a spring ring 3 to smoothly enter the aneurysm 6 through the abdicating holes 13 in the center of the bottom 11 of the stent body 1, releasing the spring ring 3 through the micro-catheter 4 to plug the aneurysm 6, releasing the spring ring 3 after the filling of the spring ring 3 is completed, then withdrawing the micro-catheter 4 for conveying the spring ring 3, adjusting the position of the intratumoral stent through the conveying pipe 5, releasing the intratumoral stent after the position of the intratumoral stent is properly adjusted, and finally withdrawing the conveying pipe 5 for conveying the intratumoral stent.
It can be understood that the stent body 1 of the invention is covered on the neck of a tumor to prevent the spring ring 3 in the tumor from falling off to the artery carrying the tumor, meanwhile, the mesh structure design of the stent body 1 can play a certain blood flow guiding role to slow down the impact of blood flow on the aneurysm 6, and the spring ring 3 can effectively prevent the stent body 1 from moving to the top of the tumor 12, thereby achieving the long-term stable embolization effect.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (7)
1. An intratumoral stent of an intracranial aneurysm is characterized by comprising a stent body and a ligation sleeve, wherein the stent body is of a net structure and is provided with a bottom and a top which are opposite to each other;
the stent body is disc-shaped in a self-expansion state, and the outer diameter of the stent body in the self-expansion state is larger than the inner diameter of the intracranial aneurysm;
the ligation sleeve is positioned at the center of the bracket body, and the abdication hole is arranged close to the center of the bracket body; or the ligation sleeve is positioned at the eccentric position of the bracket body, and the abdicating hole is positioned at the central position of the bracket body.
2. The intratumoral stent of an intracranial aneurysm as in claim 1, wherein when the abduction holes are disposed adjacent to the central position of the stent body, a plurality of the abduction holes are disposed, and the plurality of the abduction holes are circumferentially spaced apart along the ligation sleeve.
3. The intracranial aneurysm stent of claim 1, wherein the visualization ring is disposed at the relief hole.
4. The intratumoral stent of an intracranial aneurysm as in any of claims 1-3, wherein the size of the relief holes is greater than the size of the top mesh of the stent body and less than the size of the neck of the aneurysm of the intracranial aneurysm.
5. The intratumoral stent of an intracranial aneurysm as in claim 4, wherein the abduction holes are circular, diamond-shaped or oval in shape;
and defining the diameter of the inner circle of the abdicating hole as the size of the abdicating hole, wherein the diameter of the inner circle of the abdicating hole is 0.6-4mm.
6. The intratumoral stent of an intracranial aneurysm as in any one of claims 1 to 3, wherein the shape of the apical mesh of the stent body is circular, diamond-shaped or oval;
the diameter of an inscribed circle of the top mesh of the stent body is defined as the size of the top mesh, and the diameter of the inscribed circle of the top mesh of the stent body is 0.2-1mm.
7. The intratumoral stent of an intracranial aneurysm of any one of claims 1 to 3, wherein the stent body is a single-layer mesh structure woven from wires of nickel titanium, platinum-containing nickel titanium, tungsten-containing nickel titanium or tantalum-containing nickel titanium.
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EP1804719A2 (en) * | 2004-09-22 | 2007-07-11 | Lee R. Guterman | Cranial aneurysm treatment arrangement |
WO2007079402A2 (en) * | 2005-12-31 | 2007-07-12 | Levy Elad I | Bifurcation aneurysm treatment stent with distal web |
CN201139654Y (en) * | 2008-01-14 | 2008-10-29 | 明一生物科技(上海)有限公司 | Self-expanding net type bracket for intracranial artery vascular |
US9277924B2 (en) * | 2009-09-04 | 2016-03-08 | Pulsar Vascular, Inc. | Systems and methods for enclosing an anatomical opening |
US11076860B2 (en) * | 2014-03-31 | 2021-08-03 | DePuy Synthes Products, Inc. | Aneurysm occlusion device |
WO2017201263A1 (en) * | 2016-05-19 | 2017-11-23 | University Of Iowa Research Foundation | Microcatheter stent |
US11076861B2 (en) * | 2018-10-12 | 2021-08-03 | DePuy Synthes Products, Inc. | Folded aneurysm treatment device and delivery method |
US11931041B2 (en) * | 2020-05-12 | 2024-03-19 | Covidien Lp | Devices, systems, and methods for the treatment of vascular defects |
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