CN114848551A - Witch hazel soothing and bacteriostatic sanitary wet tissue and production process thereof - Google Patents
Witch hazel soothing and bacteriostatic sanitary wet tissue and production process thereof Download PDFInfo
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Abstract
The invention discloses a witch hazel soothing bacteriostatic sanitary wet tissue and a production process thereof, wherein the witch hazel soothing bacteriostatic sanitary wet tissue is prepared by soaking non-woven fabrics in an antibacterial solution; the antibacterial liquid comprises the following raw materials in parts by weight: 5-10 parts of antibacterial microcapsules, 3-5 parts of citric acid, 1-3 parts of squalane and 120 parts of purified water; the surface of the antibacterial microcapsule has certain antibacterial performance for chitosan, and meanwhile, the intermediate 7 coated inside contains a large amount of quaternary ammonium salt structures and nitrogen halogenated amine structures, so that the antibacterial microcapsule on the surface of the wet tissue is damaged under the action of external force in the using process, antibacterial components are released, and then free halogen with oxidability is generated to oxidize protein in cytoplasm, irreversible damage is caused to the activity of enzyme, finally, bacteria are inactivated, the antibacterial effect is achieved, and the antibacterial sanitary wet tissue has the antibacterial effect for a long time.
Description
Technical Field
The invention relates to the technical field of wet tissue preparation, and particularly relates to a witch hazel soothing bacteriostatic sanitary wet tissue and a production process thereof.
Background
With the continuous improvement of social and economic levels, people are no longer only satisfied with the temperature and fullness, and more people begin to pay more attention to the taste of life and improve the quality of life. The wet tissue is a disposable cleaning sanitary article prepared by selecting a wet-strength soft-fiber high-permeability base material, folding, humidifying and packaging, and becomes an essential cleaning article in daily life of people due to the characteristics of basic functions of cleaning and moisturizing skin, convenience in carrying and the like. The wet tissue is mainly used in commercial and reception places such as civil aviation, hotels, restaurants, exhibitions and the like in the past, and the personal consumption of the wet tissue is gradually increased along with the improvement of the living standard of people in recent years.
The witch hazel has the effects of astringing, resisting inflammation, resisting oxidation, resisting bacteria, relieving, nourishing skin, promoting vasoconstriction and the like, and when the witch hazel is applied to the antibacterial wet tissue, the problem that the antibacterial effect of the antibacterial wet tissue at the present stage is poor can be well solved.
Disclosure of Invention
The invention aims to provide a witch hazel soothing bacteriostatic sanitary wet tissue and a production process thereof, and solves the problems that the bacteriostatic sanitary wet tissue at the present stage has a common antibacterial effect and a short antibacterial effect duration time through an antibacterial liquid.
The purpose of the invention can be realized by the following technical scheme:
a witch hazel soothing bacteriostatic sanitary wet tissue is prepared by soaking non-woven fabrics in an antibacterial solution;
the antibacterial liquid comprises the following raw materials in parts by weight: 5-10 parts of antibacterial microcapsules, 3-5 parts of citric acid, 1-3 parts of squalane and 120 parts of purified water;
the bacteriostatic sanitary wet tissue is prepared by the following steps:
uniformly mixing the antibacterial microcapsules, citric acid, squalane and purified water to obtain an antibacterial solution, soaking the non-woven fabric in the antibacterial solution at the temperature of 60-80 ℃ for 3-5h, taking out the non-woven fabric until no liquid drips, and thus obtaining the antibacterial sanitary wet tissue.
Further, the antibacterial microcapsule is prepared by the following steps:
step A1: uniformly mixing 5, 5-dimethylhydantoin, potassium hydroxide and methanol, stirring for 1-1.5h at the rotation speed of 200-300r/min and the temperature of 60-70 ℃, distilling to remove the methanol, dissolving a substrate in N, N-dimethylformamide, stirring and adding 1, 3-dichloropropanol at the rotation speed of 200-min and the temperature of 90-100 ℃ to prepare an intermediate 1, uniformly mixing the intermediate 1, sodium dichloroisocyanurate and acetone, and reacting for 2-3h at the rotation speed of 300-min and the temperature of 20-25 ℃ to prepare an intermediate 2;
the reaction process is as follows:
step A2: uniformly mixing the intermediate 2, iminodiacetic acid, N-dimethylformamide and cerium sulfate, reacting for 5-7h under the conditions that the rotation speed is 150-200r/min and the temperature is 120-130 ℃ to obtain an intermediate 3, uniformly mixing dodecylamine, ethanol, formic acid aqueous solution and formaldehyde aqueous solution, performing reflux reaction for 8-12h under the condition that the temperature is 80-90 ℃, adjusting the pH value of reaction liquid to 10 to obtain an intermediate 4, uniformly mixing the intermediate 4 and epoxy chloropropane, and reacting for 2-4h under the conditions that the rotation speed is 200-300r/min and the temperature is 60-70 ℃ to obtain an intermediate 5;
the reaction process is as follows:
step A3: uniformly mixing p-bromoaniline, the intermediate 5 and isopropanol, adjusting the pH value of a reaction solution to 10, reacting for 6-8h at the rotation speed of 150-200r/min and the temperature of 85-90 ℃ to obtain an intermediate 6, uniformly mixing the intermediate 6, the intermediate 3, triethylamine and N, N-dimethylformamide, and reacting for 8-10h at the rotation speed of 200-300r/min and the temperature of 70-80 ℃ to obtain an intermediate 7;
the reaction process is as follows:
step A4: mixing the intermediate 7, the witch hazel extract, the gelatin solution and the chitosan solution uniformly, adding deionized water, stirring for 30-40min at the temperature of 50-55 ℃ and the pH value of 6-6.5, cooling to the temperature of 20-25 ℃, adding glutaraldehyde, reacting for 40-50min at the temperature of 30-35 ℃, filtering to remove filtrate, and drying a filter cake to obtain the antibacterial microcapsule.
Further, the molar ratio of the 5, 5-dimethylhydantoin, the potassium hydroxide and the 1, 3-dichloropropanol in the step A1 is 2:2:1, and the mass ratio of the intermediate 1 to the sodium dichloroisocyanurate is 1: 2.5.
Further, the molar ratio of the intermediate 2 to the iminodiacetic acid in the step A2 is 1:1, the molar ratio of the dodecylamine to the ethanol to the aqueous solution of formic acid to the aqueous solution of formaldehyde is 0.25mol to 50mL to 70mL to 50mL, the mass fraction of the aqueous solution of formic acid is 80%, the mass fraction of the aqueous solution of formaldehyde is 36%, and the molar ratio of the intermediate 4 to the epichlorohydrin is 1: 1.
Further, the molar ratio of the p-bromoaniline to the intermediate 5 in the step A3 is 1:2, and the molar ratio of the intermediate 6 to the intermediate 3 is 1: 1.
Further, the using amount of the intermediate 7, the witch hazel extract, the gelatin solution, the chitosan solution, the deionized water and the glutaraldehyde in the step A4 is 3.2g to 2.6g to 20mL to 18g to 120mL to 10mL, and the mass fraction of the chitosan solution is 1 g/L.
Further, the witch hazel extract is prepared by the following steps:
step B1: adding witch hazel into a pulverizer for pulverizing, soaking the pulverized witch hazel in chloroform, performing primary heating reflux for 1-1.5h at the rotation speed of 100-;
step B2: adding the first filter cake and deionized water into a reaction kettle, carrying out secondary heating reflux for 1-1.5h under the conditions of the rotation speed of 200-300r/min and the temperature of 60-65 ℃, and filtering to remove the second filter cake to obtain a second filtrate;
step B3: mixing the first filtrate and the second filtrate to obtain a mixed solution, and concentrating the mixed solution until the concentration of the mixed solution is 1.2-1.5g/mL to obtain the witch hazel extract.
Further, the mass ratio of the hamamelis virginiana to the chloroform in the step B1 is 1g to 5 mL.
Further, the amount ratio of the first filter cake and the deionized water in step B2 was 5g:3 mL.
Further, the volume ratio of the first filtrate to the second filtrate in the step B3 is 3: 5.
The invention has the beneficial effects that: the witch hazel soothing and bacteriostatic sanitary wet tissue prepared by the invention is prepared by soaking a non-woven fabric in an antibacterial liquid, the antibacterial liquid is prepared by uniformly mixing an antibacterial microcapsule, citric acid, squalane and purified water, the antibacterial microcapsule takes 5, 5-dimethylhydantoin as a raw material to react with potassium hydroxide to form potassium salt, the potassium salt reacts with 1, 3-dichloropropanol to prepare an intermediate 1, the intermediate 1 is chlorinated by sodium dichloroisocyanurate to prepare an intermediate 2, the intermediate 2 reacts with iminodiacetic acid to react alcoholic hydroxyl on the intermediate 2 with carboxyl on the iminodiacetic acid to prepare an intermediate 3, dodecylamine reacts with formic acid and formaldehyde to prepare an intermediate 4, the intermediate 4 reacts with epichlorohydrin to prepare an intermediate 5, p-bromoaniline reacts with the intermediate 5, preparing an intermediate 6, reacting the intermediate 6 with the intermediate 3 to prepare an intermediate 7, and microencapsulating the intermediate 7 and the witch hazel extract to prepare the antibacterial microcapsule, wherein the surface of the antibacterial microcapsule is chitosan with certain antibacterial performance, the intermediate 7 coated inside contains a large number of quaternary ammonium salt structures and nitrogen halogenated amine structures, and the antibacterial microcapsule on the surface of the wet tissue is damaged under the action of external force during use, so that the antibacterial components are released to generate free halogen with oxidizability to oxidize protein in cytoplasm, and irreversible damage is caused to the activity of enzyme, and finally the bacteria are inactivated to achieve the antibacterial effect, and the antibacterial sanitary wet tissue is microencapsulated to have the antibacterial effect for a long time.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
A witch hazel soothing bacteriostatic sanitary wet tissue is prepared by soaking non-woven fabrics in an antibacterial solution;
the antibacterial liquid comprises the following raw materials in parts by weight: 5 parts of antibacterial microcapsules, 3 parts of citric acid, 1 part of squalane and 100 parts of purified water;
the bacteriostatic sanitary wet tissue is prepared by the following steps:
uniformly mixing the antibacterial microcapsules, citric acid, squalane and purified water to obtain an antibacterial solution, soaking the non-woven fabric in the antibacterial solution at the temperature of 60 ℃ for 3 hours, and taking out the non-woven fabric until no liquid drips to obtain the antibacterial sanitary wet tissue.
The antibacterial microcapsule is prepared by the following steps:
step A1: uniformly mixing 5, 5-dimethylhydantoin, potassium hydroxide and methanol, stirring for 1h at the rotation speed of 200r/min and the temperature of 60 ℃, distilling to remove the methanol, dissolving a substrate in N, N-dimethylformamide, stirring and adding 1, 3-dichloropropanol at the rotation speed of 150r/min and the temperature of 90 ℃, stirring for 2h to prepare an intermediate 1, uniformly mixing the intermediate 1, sodium dichloroisocyanurate and acetone, and reacting for 2h at the rotation speed of 200r/min and the temperature of 20 ℃ to prepare an intermediate 2;
step A2: uniformly mixing the intermediate 2, iminodiacetic acid, N-dimethylformamide and cerium sulfate, reacting for 5 hours at the rotation speed of 150r/min and the temperature of 120 ℃ to obtain an intermediate 3, uniformly mixing dodecylamine, ethanol, a formic acid aqueous solution and a formaldehyde aqueous solution, performing reflux reaction for 8 hours at the temperature of 80 ℃, adjusting the pH value of a reaction solution to 10 to obtain an intermediate 4, uniformly mixing the intermediate 4 and epoxy chloropropane, and reacting for 2 hours at the rotation speed of 200r/min and the temperature of 60 ℃ to obtain an intermediate 5;
step A3: uniformly mixing p-bromoaniline, the intermediate 5 and isopropanol, adjusting the pH value of a reaction solution to 10, reacting for 6 hours at the rotation speed of 150r/min and the temperature of 85 ℃ to obtain an intermediate 6, uniformly mixing the intermediate 6, the intermediate 3, triethylamine and N, N-dimethylformamide, and reacting for 8 hours at the rotation speed of 200r/min and the temperature of 70 ℃ to obtain an intermediate 7;
step A4: uniformly mixing the intermediate 7, the witch hazel extract, the gelatin solution and the chitosan solution, adding deionized water, stirring for 30min at the temperature of 50 ℃ and the pH value of 6, cooling to the temperature of 20 ℃, adding glutaraldehyde, reacting for 40min at the temperature of 30 ℃, filtering to remove filtrate, and drying a filter cake to obtain the antibacterial microcapsule.
The witch hazel extract is prepared by the following steps:
step B1: adding witch hazel into a grinder for grinding, soaking the ground witch hazel in chloroform, heating and refluxing for 1h at the rotation speed of 100r/min and the temperature of 60 ℃, and filtering to obtain a first filter cake and a first filtrate;
step B2: adding the first filter cake and deionized water into a reaction kettle, carrying out secondary heating reflux for 1h at the rotation speed of 200r/min and the temperature of 60 ℃, and filtering to remove the second filter cake to obtain a second filtrate;
step B3: mixing the first filtrate and the second filtrate to obtain a mixed solution, and concentrating the mixed solution until the concentration of the mixed solution is 1.2g/mL to obtain the witch hazel extract.
Example 2
A witch hazel soothing bacteriostatic sanitary wet tissue is prepared by soaking non-woven fabrics in an antibacterial solution;
the antibacterial liquid comprises the following raw materials in parts by weight: 8 parts of antibacterial microcapsules, 4 parts of citric acid, 12 parts of squalane and 110 parts of purified water;
the bacteriostatic sanitary wet tissue is prepared by the following steps:
uniformly mixing the antibacterial microcapsules, citric acid, squalane and purified water to obtain an antibacterial solution, soaking the non-woven fabric in the antibacterial solution at 70 ℃ for 4 hours, and taking out the non-woven fabric until no liquid drips to obtain the antibacterial sanitary wet tissue.
The antibacterial microcapsule is prepared by the following steps:
step A1: uniformly mixing 5, 5-dimethylhydantoin, potassium hydroxide and methanol, stirring for 1.3h at the rotation speed of 200r/min and the temperature of 65 ℃, distilling to remove the methanol, dissolving a substrate in N, N-dimethylformamide, stirring and adding 1, 3-dichloropropanol at the rotation speed of 180r/min and the temperature of 95 ℃, stirring for 2.5h to prepare an intermediate 1, uniformly mixing the intermediate 1, sodium dichloroisocyanurate and acetone, and reacting for 2.5h at the rotation speed of 300r/min and the temperature of 23 ℃ to prepare an intermediate 2;
step A2: uniformly mixing the intermediate 2, iminodiacetic acid, N-dimethylformamide and cerium sulfate, reacting for 6 hours at the rotation speed of 180r/min and the temperature of 125 ℃ to obtain an intermediate 3, uniformly mixing dodecylamine, ethanol, a formic acid aqueous solution and a formaldehyde aqueous solution, performing reflux reaction for 10 hours at the temperature of 85 ℃, adjusting the pH value of a reaction solution to 10 to obtain an intermediate 4, uniformly mixing the intermediate 4 and epoxy chloropropane, and reacting for 3 hours at the rotation speed of 200r/min and the temperature of 65 ℃ to obtain an intermediate 5;
step A3: uniformly mixing p-bromoaniline, the intermediate 5 and isopropanol, adjusting the pH value of a reaction solution to 10, reacting for 7 hours at the rotation speed of 180r/min and the temperature of 88 ℃ to obtain an intermediate 6, uniformly mixing the intermediate 6, the intermediate 3, triethylamine and N, N-dimethylformamide, and reacting for 9 hours at the rotation speed of 200r/min and the temperature of 75 ℃ to obtain an intermediate 7;
step A4: uniformly mixing the intermediate 7, the witch hazel extract, the gelatin solution and the chitosan solution, adding deionized water, stirring for 35min at the temperature of 53 ℃ and the pH value of 6, cooling to the temperature of 23 ℃, adding glutaraldehyde, reacting for 45min at the temperature of 33 ℃, filtering to remove filtrate, and drying a filter cake to obtain the antibacterial microcapsule.
The witch hazel extract is prepared by the following steps:
step B1: adding witch hazel into a grinder for grinding, soaking the ground witch hazel in chloroform, heating and refluxing for 1.3h at the rotation speed of 100r/min and the temperature of 63 ℃, and filtering to obtain a first filter cake and a first filtrate;
step B2: adding the first filter cake and deionized water into a reaction kettle, carrying out secondary heating reflux for 1.3h under the conditions that the rotating speed is 300r/min and the temperature is 63 ℃, and filtering to remove a second filter cake to obtain a second filtrate;
step B3: mixing the first filtrate and the second filtrate to obtain a mixed solution, and concentrating the mixed solution until the concentration of the mixed solution is 1.3g/mL to obtain the witch hazel extract.
Example 3
A witch hazel soothing bacteriostatic sanitary wet tissue is prepared by soaking non-woven fabrics in an antibacterial solution;
the antibacterial liquid comprises the following raw materials in parts by weight: 10 parts of antibacterial microcapsules, 5 parts of citric acid, 3 parts of squalane and 120 parts of purified water;
the bacteriostatic sanitary wet tissue is prepared by the following steps:
uniformly mixing the antibacterial microcapsules, citric acid, squalane and purified water to obtain an antibacterial solution, soaking the non-woven fabric in the antibacterial solution at 80 ℃ for 5 hours, and taking out the non-woven fabric until no liquid drips to obtain the antibacterial sanitary wet tissue.
The antibacterial microcapsule is prepared by the following steps:
step A1: uniformly mixing 5, 5-dimethylhydantoin, potassium hydroxide and methanol, stirring for 1-1.5h at the rotation speed of 300r/min and the temperature of 70 ℃, distilling to remove the methanol, dissolving a substrate in N, N-dimethylformamide, stirring and adding 1, 3-dichloropropanol at the rotation speed of 200r/min and the temperature of 100 ℃, stirring for 3h to prepare an intermediate 1, uniformly mixing the intermediate 1, sodium dichloroisocyanurate and acetone, and reacting for 3h at the rotation speed of 300r/min and the temperature of 25 ℃ to prepare an intermediate 2;
step A2: uniformly mixing the intermediate 2, iminodiacetic acid, N-dimethylformamide and cerium sulfate, reacting for 7 hours at the rotation speed of 200r/min and the temperature of 130 ℃ to obtain an intermediate 3, uniformly mixing dodecylamine, ethanol, a formic acid aqueous solution and a formaldehyde aqueous solution, performing reflux reaction for 12 hours at the temperature of 90 ℃, adjusting the pH value of a reaction solution to 10 to obtain an intermediate 4, uniformly mixing the intermediate 4 and epoxy chloropropane, and reacting for 4 hours at the rotation speed of 300r/min and the temperature of 70 ℃ to obtain an intermediate 5;
step A3: uniformly mixing p-bromoaniline, the intermediate 5 and isopropanol, adjusting the pH value of a reaction solution to 10, reacting for 8 hours at the rotation speed of 200r/min and the temperature of 90 ℃ to obtain an intermediate 6, uniformly mixing the intermediate 6, the intermediate 3, triethylamine and N, N-dimethylformamide, and reacting for 10 hours at the rotation speed of 300r/min and the temperature of 80 ℃ to obtain an intermediate 7;
step A4: uniformly mixing the intermediate 7, the witch hazel extract, the gelatin solution and the chitosan solution, adding deionized water, stirring for 40min at the temperature of 55 ℃ and the pH value of 6.5, cooling to the temperature of 25 ℃, adding glutaraldehyde, reacting for 50min at the temperature of 35 ℃, filtering to remove filtrate, and drying a filter cake to obtain the antibacterial microcapsule.
The witch hazel extract is prepared by the following steps:
step B1: adding witch hazel into a grinder for grinding, soaking the ground witch hazel in chloroform, heating and refluxing for 1.5h at the rotating speed of 200r/min and the temperature of 65 ℃, and filtering to obtain a first filter cake and a first filtrate;
step B2: adding the first filter cake and deionized water into a reaction kettle, carrying out secondary heating reflux for 1.5h under the conditions that the rotating speed is 300r/min and the temperature is 65 ℃, and filtering to remove a second filter cake to obtain a second filtrate;
step B3: mixing the first filtrate and the second filtrate to obtain a mixed solution, and concentrating the mixed solution until the concentration of the mixed solution is 1.5g/mL to obtain the witch hazel extract.
Comparative example 1
The comparative example is an antibacterial sanitary wet tissue disclosed in Chinese patent CN 108158869A.
Comparative example 2
The comparative example is an antibacterial sanitary wet tissue disclosed in Chinese patent CN 108286125A.
Placing the antibacterial wet tissue prepared in the antibacterial sanitary wet tissue prepared in the examples 1-3 and the comparative examples 1-2 in a closed environment (25 ℃, the humidity is 60%), placing an open culture of escherichia coli and a culture of staphylococcus aureus in the closed environment, and measuring the colony count of the antibacterial wet tissue after placing for 12 hours, wherein the results are shown in the following table;
as shown in the table, the antibacterial activity of the antibacterial sanitary wet tissue prepared in the examples 1-3 on Escherichia coli is 50-53CFU/mL, and the antibacterial activity of Staphylococcus aureus is 48-52CFU/mL, which indicates that the antibacterial wet tissue has a good antibacterial effect.
The foregoing is merely exemplary and illustrative of the principles of the present invention and various modifications, additions and substitutions of the specific embodiments described herein may be made by those skilled in the art without departing from the principles of the present invention or exceeding the scope of the claims set forth herein.
Claims (10)
1. A witch hazel soothing bacteriostatic sanitary wet tissue is characterized in that: soaking the non-woven fabric in an antibacterial solution;
the antibacterial liquid comprises the following raw materials in parts by weight: 5-10 parts of antibacterial microcapsules, 3-5 parts of citric acid, 1-3 parts of squalane and 120 parts of purified water;
the antibacterial microcapsule is prepared by the following steps:
step A1: mixing 5, 5-dimethylhydantoin, potassium hydroxide and methanol for reaction, distilling to remove the methanol, dissolving a substrate in N, N-dimethylformamide, stirring, adding 1, 3-dichloropropanol for reaction to prepare an intermediate 1, and mixing the intermediate 1, sodium dichloroisocyanurate and acetone for reaction to prepare an intermediate 2;
step A2: uniformly mixing the intermediate 2, iminodiacetic acid, N-dimethylformamide and cerium sulfate, reacting to obtain an intermediate 3, mixing dodecylamine, ethanol, a formic acid aqueous solution and a formaldehyde aqueous solution, performing reflux reaction, adjusting the pH value of a reaction solution to obtain an intermediate 4, and mixing the intermediate 4 and epoxy chloropropane for reaction to obtain an intermediate 5;
step A3: mixing p-bromoaniline, the intermediate 5 and isopropanol for reaction to obtain an intermediate 6, and mixing the intermediate 6, the intermediate 3, triethylamine and N, N-dimethylformamide for reaction to obtain an intermediate 7;
step A4: and (3) uniformly mixing the intermediate 7, the witch hazel extract, the gelatin solution and the chitosan solution, adding deionized water, continuously stirring, cooling, adding glutaraldehyde, reacting, filtering to remove filtrate, and drying a filter cake to obtain the antibacterial microcapsule.
2. The witch hazel soothing bacteriostatic sanitary wet wipe as claimed in claim 1, wherein: the molar ratio of the 5, 5-dimethylhydantoin, the potassium hydroxide and the 1, 3-dichloropropanol in the step A1 is 2:2:1, and the mass ratio of the intermediate 1 to the sodium dichloroisocyanurate is 1: 2.5.
3. The witch hazel soothing bacteriostatic sanitary wet wipe as claimed in claim 1, wherein: the molar ratio of the intermediate 2 to the iminodiacetic acid in the step A2 is 1:1, the molar ratio of the dodecylamine, the ethanol, the formic acid aqueous solution to the formaldehyde aqueous solution is 0.25mol:50mL:70mL:50mL, the mass fraction of the formic acid aqueous solution is 80%, the mass fraction of the formaldehyde aqueous solution is 36%, and the molar ratio of the intermediate 4 to the epichlorohydrin is 1: 1.
4. The witch hazel soothing bacteriostatic sanitary wet wipe as claimed in claim 1, wherein: the molar ratio of the p-bromoaniline to the intermediate 5 in the step A3 is 1:2, and the molar ratio of the intermediate 6 to the intermediate 3 is 1: 1.
5. The witch hazel soothing bacteriostatic sanitary wet wipe as claimed in claim 1, wherein: the using amount ratio of the intermediate 7, the witch hazel extract, the gelatin solution, the chitosan solution, the deionized water and the glutaraldehyde which are described in the step A4 is 3.2g, 2.6g, 20mL, 18g, 120mL and 10mL, and the mass fraction of the chitosan solution is 1 g/L.
6. The witch hazel soothing bacteriostatic sanitary wet wipe as claimed in claim 1, wherein: the witch hazel extract is prepared by the following steps:
step B1: adding witch hazel into a grinder for grinding, soaking the ground witch hazel in chloroform, heating and refluxing, and filtering to obtain a first filter cake and a first filtrate;
step B2: adding the first filter cake and deionized water into a reaction kettle, heating and refluxing, and filtering to remove the second filter cake to obtain a second filtrate;
step B3: mixing the first filtrate and the second filtrate to obtain a mixed solution, and concentrating the mixed solution to obtain the witch hazel extract.
7. The witch hazel soothing bacteriostatic sanitary wet wipe as claimed in claim 1, wherein: step B18, wherein the mass ratio of the hamamelis and chloroform is 1g to 5 mL.
8. The witch hazel soothing bacteriostatic sanitary wet wipe as claimed in claim 1, wherein: the amount ratio of the first filter cake in step B2 to the deionized water was 5g:3 mL.
9. The witch hazel soothing bacteriostatic sanitary wet wipe as claimed in claim 1, wherein: the volume ratio of the first filtrate to the second filtrate in the step B3 is 3: 5.
10. The production process of the witch hazel soothing bacteriostatic sanitary wet tissue as claimed in claim 1, wherein the production process comprises the following steps: the method specifically comprises the following steps:
uniformly mixing the antibacterial microcapsules, citric acid, squalane and purified water to obtain an antibacterial solution, soaking the non-woven fabric in the antibacterial solution at the temperature of 60-80 ℃ for 3-5h, and taking out the non-woven fabric until no liquid drips to obtain the antibacterial sanitary wet tissue.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116607322A (en) * | 2023-07-06 | 2023-08-18 | 成都尚元太生物科技有限公司 | Polymer biological material for selectively removing activated white blood cells |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116607322A (en) * | 2023-07-06 | 2023-08-18 | 成都尚元太生物科技有限公司 | Polymer biological material for selectively removing activated white blood cells |
| CN116607322B (en) * | 2023-07-06 | 2023-10-13 | 成都尚元太生物科技有限公司 | Polymer biological material for selectively removing activated white blood cells |
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