CN114847885A - Method, device and system for presenting brain function connection map and storage medium - Google Patents

Method, device and system for presenting brain function connection map and storage medium Download PDF

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CN114847885A
CN114847885A CN202210520098.8A CN202210520098A CN114847885A CN 114847885 A CN114847885 A CN 114847885A CN 202210520098 A CN202210520098 A CN 202210520098A CN 114847885 A CN114847885 A CN 114847885A
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邓皓
汪待发
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Danyang Huichuang Medical Equipment Co ltd
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    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2576/00Medical imaging apparatus involving image processing or analysis
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Abstract

The invention relates to a method, a device and a system for presenting a brain function connection map and a storage medium. The presentation method includes acquiring medical data characterizing a brain functional state of a subject, calculating brain functional connection strengths between respective locations on a brain region based on the acquired medical data; displaying a brain function connection map in a display interface based on the calculated brain function connection strength between the positions, wherein the brain function connection map comprises brain area identifications and image blocks corresponding to the brain function connection strength between the positions; the positions are arranged according to the brain areas to which the positions belong, so that the image blocks are correspondingly arranged in the corresponding blocks which are arranged at intervals according to the brain areas to which the positions associated with the image blocks belong. According to the invention, the positions are arranged according to the brain areas in a partition manner, and the image blocks of different brain areas are arranged at intervals, so that a user can more conveniently judge the corresponding position relation of the image blocks and the brain areas to which the image blocks belong, the error probability of information acquisition is reduced, and the diagnosis and analysis are facilitated.

Description

Method, device and system for presenting brain function connection map and storage medium
Technical Field
The invention relates to the technical field of medical diagnosis, in particular to a method, a device, a system and a storage medium for presenting a brain function connection map.
Background
Through brain function detection equipment such as near infrared spectrum detection equipment, electroencephalogram equipment, nuclear magnetic resonance imager, functional magnetic resonance imager, positron emission computed tomography imager and the like, medical data such as near infrared data, electroencephalogram data, MRI images, fMRI images, PET images and the like which represent the brain function state of a detected person can be obtained, but in the existing various technologies which utilize the brain function data to provide diagnosis support for doctors, the defects that the presentation mode is not intuitive enough and is not convenient enough exist, for example, in the existing functional connection map generated by utilizing the brain function data, color blocks used for representing the connection relation of all positions of the brain of the detected person are gathered and arranged together, particularly under the condition that the brain detection positions are more, a user is difficult to obtain the specific information of all the color blocks, for example, a channel or a brain region which needs to be concerned is difficult to determine, it is inconvenient for a doctor to analyze the diagnosis.
Disclosure of Invention
The present invention is provided to solve the above-mentioned drawbacks in the prior art. There is a need for a method, an apparatus, a system, and a storage medium for presenting a brain function connection map, which can display a brain function connection map calculated based on acquired medical data on a display interface, wherein brain function connection strength image blocks between positions are clearly distributed in corresponding blocks in a mode of intra-brain-area concentration and inter-brain-area spacing, so that a user can conveniently, clearly, and accurately view brain function connection information between positions belonging to the same or different brain areas, and simultaneously view brain function connection information between positions and positions in a specific brain area in a concentrated manner, thereby greatly reducing the probability of errors in information acquisition, and further improving the accuracy, reliability, and efficiency of clinical diagnosis.
A first aspect of the present invention provides a method of presenting a brain function connection map, the method including acquiring medical data capable of characterizing a brain function state of a subject, calculating brain function connection strengths between respective positions on a brain region based on the acquired medical data; displaying a brain function connection map in a display interface based on the calculated brain function connection strength among the positions, wherein the brain function connection map comprises brain area identifications and image blocks corresponding to the brain function connection strength among the positions; the positions are arranged according to the brain areas to which the positions belong, so that the image blocks are correspondingly arranged in the corresponding blocks which are arranged at intervals according to the brain areas to which the positions associated with the image blocks belong.
A second aspect of the invention provides a device for presenting a brain function connection atlas, the device comprising at least a processor and a memory, the memory having stored thereon computer-executable instructions, the processor performing the operations of the method for presenting a brain function connection atlas according to various embodiments of the invention when executing the computer-executable instructions.
A third aspect of the invention provides a near-infrared brain function imaging system, which comprises a near-infrared spectrum detection device and a brain function connection map presentation device as described above.
A fourth aspect of the present invention provides a non-transitory computer-readable storage medium storing a program for causing a processor to perform various operations of a method of presenting a brain function connection map according to various embodiments of the present invention.
The invention provides a method, a device and a system for presenting a brain function connection map and a storage medium, by displaying a brain function connection map calculated based on the acquired medical data on a display interface and arranging the respective positions in regions according to brain regions, and the image blocks of different brain areas are arranged at intervals, so that the brain function connection strength image blocks at various positions are clearly distributed in the corresponding blocks in a mode of concentration in the brain areas and interval among the brain areas, thus, the user can conveniently, clearly and accurately check the brain function connection information between the positions belonging to the same or different brain areas, meanwhile, the brain function connection information between each position in the specific brain area and the positions of other brain areas can be intensively checked, so that the error probability in information acquisition is greatly reduced, and the accuracy and reliability of diagnosis and the efficiency of clinical diagnosis can be improved.
Drawings
In the drawings, which are not necessarily drawn to scale, like reference numerals may describe similar components in different views. Like reference numerals having letter suffixes or different letter suffixes may represent different instances of similar components. The drawings illustrate various embodiments generally by way of example and not by way of limitation, and together with the description and claims serve to explain the disclosed embodiments. Such embodiments are illustrative, and are not intended to be exhaustive or exclusive embodiments of the present apparatus or method.
Fig. 1 shows a flow chart of a method of presenting a brain function connection map according to an embodiment of the present invention.
Figure 2 illustrates a schematic diagram of an exemplary brain function connection map based on near infrared data, in accordance with an embodiment of the present invention.
Fig. 3 is a schematic diagram illustrating a brain function connection map and an SD map in association with each other according to an embodiment of the present invention.
Fig. 4 is a schematic partial structural diagram of a brain function connection map presenting apparatus according to an embodiment of the present invention.
Fig. 5 shows a partial composition schematic diagram of a near-infrared brain function imaging system according to an embodiment of the invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the drawings of the embodiments of the present invention. It is to be understood that the embodiments described are only a few embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the described embodiments of the invention without any inventive step, are within the scope of protection of the invention.
Unless defined otherwise, technical or scientific terms used herein shall have the ordinary meaning as understood by one of ordinary skill in the art to which this invention belongs. The word "comprising" or "comprises", and the like, means that the element or item listed before the word covers the element or item listed after the word and its equivalents, but does not exclude other elements or items.
To maintain the following description of the embodiments of the present invention clear and concise, a detailed description of known functions and known components of the invention have been omitted.
Fig. 1 shows a flow chart of a method of presenting a brain function connection map according to an embodiment of the present invention.
First, in operation S101, medical data, such as near infrared data, which can characterize a brain function state of a subject, may be acquired by a brain function detecting device, such as a near infrared spectrum detecting device, and brain function connection strength between respective locations on a brain region is calculated based on the acquired medical data. However, it should be understood that the medical data is not limited to near infrared data obtained by a near infrared spectrum detection device, and may be acquired by any other suitable technique and device, such as electroencephalogram data, MRI images, fMRI images, PET images, etc. Wherein, when the medical data is near infrared data, each position is a channel position, and when the medical data is electroencephalogram data, each position can be an electroencephalogram electrode position, and the like.
Then, in operation S102, a brain function connection map may be generated and displayed in the display interface based on the brain function connection strengths between the locations calculated in operation S101, wherein the brain function connection map may include, for example, brain region identifiers of the respective brain regions and image blocks corresponding to the brain function connection strengths between the locations. In some embodiments, the locations may correspond to, for example, channel locations in an SD layout from which near infrared spectroscopy is performed, or the like. The number of brain regions may be determined according to the specific requirements of the brain function detection, for example, 2 brain regions, 4 brain regions, 6 brain regions, etc., which is not limited in the present invention.
Taking the near infrared spectrum detection technology as an example, the brain function connection strength between the channels can directly or indirectly reflect the brain function state of the examinee, for example, for a newborn examinee, the brain function connection strength between different brain regions can reflect the phenomena of central node development retardation, low coordination capacity between the brain regions, low information transmission and integration efficiency and the like of an infant in the development process due to hypoxia and ischemia and the like, for example, the brain function connection strength between different brain regions can reflect the strength of the communication capacity between the brain regions and the like, so that the brain function connection strength information between the brain regions and the positions can be quickly and accurately acquired, and the brain function connection strength information has important significance for measuring the brain function state of the examinee, evaluating the brain injury condition, recovering condition or positioning the associated brain regions and/or position information and the like.
Taking the near infrared spectrum detection technology as an example, during detection, a plurality of pairs of probes are arranged on the head of a detected person, each pair of probes (including a transmitting probe and a receiving probe) are arranged to form a channel, and the brain function connection strength between each pair of channels can be represented by image blocks, that is, the brain function connection atlas may include hundreds of thousands of image blocks. In the method for presenting a brain function connection map according to the embodiment of the present invention, the inventor creatively arranges the positions according to the brain regions to which the positions belong, so that the image blocks are correspondingly arranged in the corresponding blocks arranged at intervals according to the brain regions to which the positions associated with the image blocks belong.
In some embodiments, the background of the display interface has a color, which may be a plurality of colors, such as white, gray, black, etc., as long as the color of the background of the display interface can be distinguished from the color of the image block, so that the user can obtain information, such as brain function connection strength between each brain region, each brain interval, and each position on each brain region, from the brain function connection map, which is not specifically limited by the present disclosure.
According to the brain function connection map displayed in the manner, the image blocks associated with the positions in the specific brain areas are arranged in the brain function connection map in an aggregation mode according to the areas, and due to the interval among the brain areas, a user can quickly and accurately locate information of one or a group of brain function connection strengths between the specific brain areas and/or the specific positions in the specific brain areas and other brain areas and/or other brain areas which the user wants to view. In other embodiments, when the user finds an abnormal image block in the brain function connection map, the arrangement of the brain region and the image block may also enable the user to quickly and accurately obtain the brain region and the position information corresponding to the concerned image block. In some embodiments, especially under the condition that there are many brain function locations and the data dimension included in the brain function connection map is large, the method for presenting a brain function connection map according to the embodiments of the present invention may provide a user with a convenient and accurate bidirectional index for viewing a specific (one or one group of) image block according to the associated brain region and location information, or viewing the corresponding brain region and location according to the concerned image block, thereby improving the efficiency and accuracy of subsequent brain function state evaluation and the like.
Figure 2 illustrates a schematic diagram of an exemplary brain function connection map based on near infrared data, in accordance with an embodiment of the present invention. The method for presenting a brain function connection map according to an embodiment of the present invention will be further described with reference to fig. 2.
As shown in fig. 2, in the brain function connection map 200 calculated based on the near-infrared data of the brain of the subject, which includes 6 brain regions, in some embodiments, the brain regions may be arranged in a preset order, for example, sequentially: in fig. 2, the brain area identifier on the left side represents one brain area associated with each image block in the brain function connection map 200, and the brain area identifier on the lower portion of fig. 2 represents another of the two brain areas associated with each image block, and all the brain areas are arranged in the order of the right forehead, the right temporal lobe, the left temporal lobe, and the left forehead, and correspondingly, the brain area identifiers on the lower portion of each brain area are arranged in the same order, so that 6 × 6 — 36 blocks in fig. 2 may be arranged in a preset order, and only as an example, the blocks corresponding to each pair of brain areas may be numbered in the order from top to bottom and from left to right: panel B1 corresponds to right anterior forehead-right forehead, panel B2 corresponds to right anterior forehead-right temporal lobe, panel B3 corresponds to right anterior forehead-right top lobe … …, and panel B36 corresponds to left forehead-left forehead. Thus, the positions may be arranged according to the brain regions to which they belong, for example, the two brain regions associated with the image block I201 in the figure are the right anterior forehead-the right top lobe, and thus, they are arranged in the block B3 in fig. 2.
As shown in fig. 2, the background of the display interface presented by the brain function connection atlas 200 is white, and each image block is an image block with a color (wherein the color of the image block is not shown), wherein the color of the image block corresponds to the brain function connection intensity value.
As shown in the legend on the right part of fig. 2, the color of each image block corresponds to the brain function connection intensity value between the positions associated with the color of each image block, which may be a real brain function connection intensity value, or a normalized intensity value for convenience of representation.
Since the respective patches are arranged at intervals as described above, a significant region aggregation effect is exhibited between the respective patches with the background white as a boundary. In other embodiments, the tiles may be arranged at equal intervals, as shown in fig. 2, the tiles B1 through B36 are arranged at equal intervals in a preset order, so that the tiles may be completely aligned according to their associated positions, thereby enabling the user to perform bidirectional search of the tiles and the corresponding positions and brain areas more quickly and accurately.
In some embodiments, the brain function connection atlas may further include a location identifier, such as the number of channels when near infrared data measurement is performed as shown in fig. 2, which may be used as the location identifier, such as the image block I201 in fig. 2, and its associated location may be the number of channel x and channel y, where x and y are two channels. It should be noted that when the image blocks in the brain function connection map 200 are dense and cannot display the position identifiers one by one, at least part of the position identifiers which are not required to be displayed temporarily may be hidden in a default state, so that the display interface only displays necessary information and keeps concise and clear.
In some embodiments, in order to enable the user to view the information in the brain function connection atlas 200 more clearly, various interaction operations may also be performed, for example, a first interaction may be performed on one or more image patches, and in response to the first interaction of the user on the brain function connection atlas, the respective image patch to which the first interaction is applied by the user may be hover enlarged. Particularly, in the case that the image blocks in the brain function connection map 200 are dense, when a user tries to view a specific image block in detail, for example, a first interaction may be applied to the image block I201 by a mouse click, a double click, a menu bar, or a right-click menu option, and the image block may be enlarged in a floating manner based on its original position so as to facilitate the user's viewing.
In some other embodiments, in addition to the hover zoom-in of each image patch to which the user applies the first interaction, the location identifier and/or the value of the brain functional connection strength corresponding to each image patch may be displayed independently or additionally. For example, for the image block I201, the numerical value (0.41) of the functional connection strength may be displayed on the enlarged image block, and/or the position identifiers x and y corresponding to the image block I201 may also be displayed on the enlarged image block or other suitable positions, for example only, the format of the position identifier display may be (x, y), x-y, or x: y, and the invention is not limited thereto. In other embodiments, when the numerical value of the functional connection strength is displayed, a numerical value consistent with the corresponding color in the legend may be displayed, and when the numerical value is a normalized value, the numerical value before normalization stored in the system may also be presented to the user at this time for reference when the doctor user performs diagnosis.
In other embodiments, on the basis of the above two operations, independently or additionally, the position identifiers of the respective image blocks to which the user applies the first interaction may also be displayed on the corresponding sides of the brain function connection atlas. In some embodiments, the position identifiers x and y associated with the image block I201 may be respectively identified on the other two sides where the brain area identifier is not displayed.
In other embodiments, the image blocks of the first interaction applied by the user may be multiple, for example, the image blocks of all other positions associated with a specific position may be image blocks corresponding to a row or a column of image blocks in the brain function connection atlas 200, in which case, the position identifiers and/or the values of the brain function connection strengths corresponding to the respective image blocks may be displayed on or around the respective image blocks enlarged in suspension, or information of the image blocks focused by the respective users may be displayed in a list at a suitable position in the display interface, etc., which are not listed herein.
According to the embodiment of the invention, through the first interaction, the user can be helped to conveniently master the brain function connection strength between the specific position concerned by the user and other one or more positions, and more accurate analysis and diagnosis can be made on the basis of the brain function connection strength.
In some embodiments, the user may also have a second interaction with brain region identification in brain function connection map 200. In response to a second interaction of the user with the functional connectivity graph, for example, image patches associated with respective locations in a brain region corresponding to a brain region identification to which the second interaction was applied by the user may be hover enlarged.
By way of example only, when the user has implemented a second interaction with the right forehead brain area identification on the left side of the brain function connection map 200 via a mouse click, double click, menu bar, or right-click menu option, etc., then all image blocks associated with the various locations associated with the right forehead, i.e., right forehead-right forehead (block B1), right forehead-right temporal lobe (block B2), right forehead-right parietal lobe (block B3), right forehead-left parietal lobe (block B4), right forehead-left temporal lobe (block B5), right forehead-left forehead (block B6), will be hover enlarged. In other embodiments, for example, when the user performs the second interaction not only on a certain brain region identifier on the left side of the brain function connection map 200, such as the right forehead, but also on one or more brain region identifiers on the lower side, such as the right temporal lobe and the right parietal lobe, then only the respective image blocks in the two blocks of the simultaneous right forehead-right temporal lobe (block B2) and right forehead-right parietal lobe (block B3) will be enlarged in suspension.
In some embodiments, while the image blocks associated with the positions in the brain region corresponding to the brain region identifier applied by the user for the second interaction are enlarged in a floating manner, the image blocks in the brain region corresponding to the brain region identifier applied by the user for the second interaction may be switched to a matrix composed of numerical values of the functional connection strength corresponding to the image blocks, so that the user can intuitively know specific numerical values of the functional connection strength of the brain between the positions in the concerned brain region, and in other embodiments, the numerical matrix may be further subjected to operations such as holding, and the like, so as to be used for subsequent calculation, processing, and the like.
According to the embodiment of the invention, through the second interaction, the brain function connection relation and the specific function connection strength between different brain areas can be visually checked by the user, so that favorable support can be provided for auxiliary analysis and accurate diagnosis of the characteristics of the brain function condition related to the brain function connection strength across the brain areas.
Fig. 3 is a schematic diagram illustrating a brain function connection map displayed in association with an SD layout according to an embodiment of the present invention. As shown in fig. 3, in the case where the brain function connection map 200 displayed in the first area a1 of the display interface is generated based on near-infrared data, the SD arrangement map 300 may also be displayed in the second area a2 of the display interface, so that the user can view the SD arrangement map 300 against the generated brain function connection map 200.
In general, a near infrared spectrum detection apparatus has a head cap, wherein the head cap may have a plurality of probes for transmitting and/or receiving near infrared signals thereon, or may be provided with mounting positions for the respective probes, and when performing measurement, each of the plurality of probes may be specifically configured as a transmitting probe (S) or a receiving probe (D) according to an SD arrangement pattern to be used for current measurement, wherein each pair of probes arranged in pairs forms a channel, wherein one transmitting probe may correspond to a plurality of receiving probes, or vice versa, one receiving probe corresponds to a plurality of transmitting probes, and the pair relationship thereof may be specifically set in the SD arrangement pattern according to a brain region or the like to be detected. After the transmitting/receiving states of the probes on the headgear of the near infrared spectrum detection apparatus are set according to the SD arrangement diagram, near infrared data in the brain regions of the examinee can be acquired, and the brain function connection map 200 can be further generated based on the acquired near infrared data. By way of example only, one specific algorithm for generating a brain function connection map 200 based on near infrared data is as follows.
First, the time series of near-infrared data for each channel can be consideredIs equal, the Pearson correlation coefficient r of the time series of arbitrary channel pairs (channel i and channel j) is calculated by the following formula (1) ij And r is ij As a quantified value of the brain functional connection strength between channel i and channel j:
Figure BDA0003641256850000081
wherein n represents the length of the time series, k represents the kth point on the time series, X i (k) And X j (k) Time series X respectively representing channels i i And time series X of channel j j The sampled value at the k-th point,
Figure BDA0003641256850000082
and
Figure BDA0003641256850000083
respectively represent X i And X j Mean over the entire time series.
The quantified value of the brain function connection strength between each channel pair can be obtained through the formula (1). As can be seen from the brain function connection map 200, the matrix formed by the respective image blocks is a matrix symmetrical along the diagonal.
In the mode of viewing the brain function connection map 200 in comparison with the SD arrangement map 300, the user may implement a third interaction on one or more image blocks in the brain function connection map 200 by clicking with a mouse, double clicking, menu bar or right-click menu option, etc., and in response to the third interaction on the brain function connection map by the user, highlight channel information corresponding to the one or more image blocks on the SD arrangement map 300 to which the user applies the third interaction. In some embodiments, for example, when a third interaction is applied to the image block I301 in the brain function connection map 200, correspondingly, two channels associated with the image block I301, the channel identifiers of the channel 3 located on the left forehead and the channel 49 located on the right temporal lobe and line segments thereof may be thickened and/or highlighted on the SD layout 300, or a highlighting operation such as a blinking highlighting operation, which is not particularly limited herein. In some embodiments, the user may also apply the third interaction to the plurality of image blocks at the same time, and when the channels associated with the plurality of image blocks are highlighted on the SD layout 300, for example, a pair of channels corresponding to a specific image block may be identified and highlighted in the same color as the image block on the SD layout 300, and the invention is not limited in specific manner.
Since the SD layout 300 can visually check the positions of the channels relative to the brain region, the relative relationships with other nearby channels, and the like, the brain function connection map 200 is checked against the SD layout 300 according to the embodiment of the present invention, and the response to the third interaction of the user is beneficial for the user to check the exact and detailed strength values, positions, brain regions, and other comprehensive information of the brain function connection concerned by the user simultaneously and comparatively.
In some embodiments, the presentation method further comprises: in response to a fourth interaction of the user with the brain function connection atlas, the tiles and/or image blocks in the tiles are highlighted. In some embodiments, the fourth interaction may be a selection operation such as a click operation, a mouse-over operation, and the like performed by the user on the block and/or an image block in the block, and based on the fourth interaction performed by the user, the corresponding content may be highlighted, for example, the unselected content may be weakened by containing other unselected contents in ash, blurring, and the like, or the selected content may be highlighted by floating, enlarging, adding a border line, and the like, or the weakening manner of the unselected content may be combined with the highlighting manner of the selected content, as long as the selected content can be highlighted, so that the user can quickly obtain information of the selected content, which is not specifically limited by the present disclosure. In one embodiment, a user may connect to a block on the atlas by clicking on brain functions, for example, clicking on a block corresponding to the top right leaf and the top left leaf shown in fig. 2, and in response to a click operation on the block by the user, all other non-selected blocks may be grayed out, so that the block can be highlighted, so that the block can be focused on, and the whole information of the block and the information of each image block located in the block can be quickly obtained.
Fig. 4 is a schematic partial structural diagram of a brain function connection map presenting apparatus according to an embodiment of the present invention. As shown in fig. 4, the apparatus 400 for presenting a brain function connection atlas may comprise at least a processor 401 and a memory 402, wherein the memory 402 has stored thereon computer-executable instructions, such that the processor 401, when executing the computer-executable instructions, performs the operations of the method for presenting a brain function connection atlas according to various embodiments of the present invention.
Processor 401 may be a processing device, such as a microprocessor, Central Processing Unit (CPU), Graphics Processing Unit (GPU), etc., including one or more general-purpose processing devices. More specifically, processor 401 may be a Complex Instruction Set Computing (CISC) microprocessor, Reduced Instruction Set Computing (RISC) microprocessor, Very Long Instruction Word (VLIW) microprocessor, processor running other instruction sets, or processors running a combination of instruction sets. Processor 401 may also be one or more special-purpose processing devices such as an Application Specific Integrated Circuit (ASIC), a Field Programmable Gate Array (FPGA), a Digital Signal Processor (DSP), a system on a chip (SoC), or the like. Processor 401 may be communicatively coupled to memory 402 and configured to execute computer-executable instructions stored thereon to perform the methods of presenting a brain function connection atlas of the various embodiments described above.
The memory 402 may be a non-transitory computer-readable medium, such as Read Only Memory (ROM), Random Access Memory (RAM), phase change random access memory (PRAM), Static Random Access Memory (SRAM), Dynamic Random Access Memory (DRAM), Electrically Erasable Programmable Read Only Memory (EEPROM), other types of Random Access Memory (RAM), flash disk or other forms of flash memory, cache, registers, static memory, compact disk read only memory (CD-ROM), Digital Versatile Disks (DVD) or other optical storage, magnetic cassettes or other magnetic storage devices, or any other possible non-transitory medium that can be used to store information or instructions that can be accessed by a computer device, and so forth. In addition, a brain function connection map and the like acquired by a brain function detection device such as a near infrared spectrum detection device and the like for generating the brain function connection map and the like to be presented on a display interface can be stored, and a user indicates that the stored data and indexes and the like need to be recorded based on various interaction.
According to the device 400 for presenting a brain function connection map of the embodiment of the present invention, the brain function connection map calculated based on the acquired medical data can be displayed on the display interface, wherein the brain function connection strength between each position is represented by the colored image blocks, and each image block is clearly distributed in the corresponding block in the mode of the brain area concentration and the brain area interval, so that a convenient and fast way for a user to clearly and accurately view the brain function connection information between the positions belonging to the same or different brain areas can be provided, and simultaneously, the brain function connection information between each position and each position in a specific brain area can be collectively viewed, thereby greatly reducing the error probability during information acquisition, and further improving the accuracy, reliability and clinical diagnosis efficiency.
Fig. 5 shows a partial schematic composition diagram of a near-infrared brain function imaging system according to an embodiment of the invention. As shown in fig. 5, the near-infrared brain function imaging system 500 includes a near-infrared spectrum detection device 501 and a brain function connection map presentation apparatus 400, wherein the brain function connection map presentation apparatus 400 implements various operations of the brain function connection map presentation method according to the embodiments of the present invention.
According to the near-infrared brain function imaging system 500 of the embodiment of the present invention, near-infrared data representing the brain function state of the subject can be acquired by using the near-infrared spectrum detection device 501, and based on the near-infrared data, a brain function connection map of the subject is calculated and displayed on the display interface, in the brain function connection map, each position is arranged according to a brain region, the brain function connection strength between each position is represented by an image block with color, and the image blocks of different brain regions are arranged at intervals, so that the brain function connection strength image blocks between each position are clearly distributed in the corresponding block in a mode of intra-brain region concentration and inter-brain region interval. Thus, according to the near-infrared brain function imaging system 500 provided by the embodiment of the invention, a user can not only acquire near-infrared data representing the brain function state of a subject, but also conveniently, clearly and accurately check the brain function connection information between the positions of the subject belonging to the same or different brain areas in a brain function connection map manner, and simultaneously can intensively check the brain function connection information between each position in a specific brain area and the positions of other brain areas, so that the error probability during information acquisition is greatly reduced, and more accurate, more reliable and more efficient clinical diagnosis basis for the subject can be provided for the user.
Moreover, although exemplary embodiments have been described herein, the scope thereof includes any and all embodiments based on the present invention with equivalent elements, modifications, omissions, combinations (e.g., of various embodiments across), adaptations or alterations. The elements of the claims are to be interpreted broadly based on the language employed in the claims and not limited to examples described in the present specification or during the practice of the invention, which examples are to be construed as non-exclusive. It is intended, therefore, that the specification and examples be considered as exemplary only, with a true scope and spirit being indicated by the following claims and their full scope of equivalents.
The above description is intended to be illustrative and not restrictive. For example, the above-described examples (or one or more versions thereof) may be used in combination with each other. For example, other embodiments may be used by those of ordinary skill in the art upon reading the above description. In addition, in the above-described embodiments, various features may be grouped together to streamline the disclosure. This should not be interpreted as an intention that a disclosed feature not claimed is essential to any claim. Rather, inventive subject matter may lie in less than all features of a particular disclosed embodiment. Thus, the following claims are hereby incorporated into the detailed description as examples or embodiments, with each claim standing on its own as a separate embodiment, and it is contemplated that these embodiments may be combined with each other in various combinations or permutations. The scope of the invention should be determined with reference to the appended claims, along with the full scope of equivalents to which such claims are entitled.
The above embodiments are only exemplary embodiments of the present invention, and are not intended to limit the present invention, and the scope of the present invention is defined by the claims. Various modifications and equivalents of the invention may be made by those skilled in the art within the spirit and scope of the invention, and such modifications and equivalents should also be considered as falling within the scope of the invention.

Claims (11)

1. A method for presenting a brain function connection map, the method comprising:
acquiring medical data capable of representing the brain function state of a subject, and calculating brain function connection strength between positions on a brain area based on the acquired medical data;
displaying a brain function connection map in a display interface based on the calculated brain function connection strength between the positions, wherein the brain function connection map comprises brain area identifications and image blocks corresponding to the brain function connection strength between the positions;
the positions are arranged according to the brain areas to which the positions belong, so that the image blocks are correspondingly arranged in the corresponding blocks which are arranged at intervals according to the brain areas to which the positions associated with the image blocks belong.
2. The presentation method according to claim 1, wherein the medical data is near infrared data.
3. The rendering method as claimed in claim 1, wherein the blocks are arranged in a predetermined order, and the blocks are arranged at equal intervals.
4. The rendering method according to claim 1, wherein the background of the display interface is white, and the image blocks are image blocks having colors, wherein,
the color of the image block corresponds to the brain function connection intensity value.
5. The presentation method according to any one of claims 1-4, wherein the brain function connection map further comprises a location identifier, the presentation method further comprising: in response to a first interaction by a user with the brain function connection map,
suspending and amplifying each image block of the first interaction applied by the user; and/or
Suspending and amplifying each image block applied by a user for the first interaction, and displaying a position identifier and/or a numerical value of brain function connection strength corresponding to each image block; and/or
And displaying the position identification of each image block of the first interaction applied by the user on the corresponding side of the brain function connection map.
6. The presentation method according to any one of claims 1 to 4, wherein the presentation method further comprises: in response to a second interaction by the user with the brain function connection map,
suspending and amplifying image blocks associated with all positions in the brain area corresponding to the brain area identification of the second interaction applied by the user; and/or
And suspending and amplifying the image blocks associated with the positions in the brain area corresponding to the brain area identification applied by the user with the second interaction, and switching the image blocks in the brain area corresponding to the brain area identification applied by the user with the second interaction into a matrix formed by numerical values of the functional connection strength corresponding to the image blocks.
7. The presentation method according to claim 2, characterized in that the method further comprises:
displaying an SD layout corresponding to the near infrared data in the display interface;
in response to a third interaction of the user on the brain function connection map, highlighting channel information corresponding to an image block applied by the user to the third interaction on the SD layout.
8. The presentation method according to any one of claims 1 to 4, wherein the presentation method further comprises: highlighting the tile and/or an image tile in the tile in response to a fourth interaction of the user with the brain function connection atlas.
9. An apparatus for presentation of a brain function connection atlas, the apparatus comprising at least a processor and a memory, the memory having stored thereon computer-executable instructions that, when executed, perform operations of the method for presentation of a brain function connection atlas according to any one of claims 1-7.
10. A near-infrared brain function imaging system, characterized in that the system comprises a near-infrared spectrum detection device and a brain function connection map presentation apparatus according to claim 9.
11. A non-transitory computer-readable storage medium storing a program that causes a processor to perform operations of the method of presenting a brain function connection map according to any one of claims 1-8.
CN202210520098.8A 2022-05-12 2022-05-12 Method, device and system for presenting brain function connection map and storage medium Pending CN114847885A (en)

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