CN114800453B

CN114800453B - Electrode clamping device for liquid interaction

Info

Publication number: CN114800453B
Application number: CN202210609897.2A
Authority: CN
Inventors: 刘文昊; 韩传亮; 蔚鹏飞; 王立平
Original assignee: Shenzhen Institute of Advanced Technology of CAS
Current assignee: Shenzhen Institute of Advanced Technology of CAS
Priority date: 2022-05-31
Filing date: 2022-05-31
Publication date: 2023-09-01
Anticipated expiration: 2042-05-31
Also published as: CN114800453A

Abstract

The invention discloses an electrode clamping device for liquid interaction, and belongs to the technical field of liquid interaction. According to the electrode clamping device for liquid interaction, the electrode can be fixedly arranged on the clamping rod, the clamping rod is controlled to slide along the clamping head, so that the electrode stretches into the container and is contacted with the impregnating liquid contained in the container to be impregnated and dyed or cleaned, the clamping head is used for supporting the clamping rod, accidental shaking of hands of an experimenter can be effectively avoided, and the electrode is prevented from being knocked or broken, so that the electrode is protected; meanwhile, the clamping rod can be clamped by the clamping head through controlling the clamping adjusting piece, so that the electrode can be kept in the state after the electrode stretches into the container and is contacted with the infiltration liquid, an experimenter does not need to hold the electrode for a long time, and the electrode is further protected; the container is fixedly arranged on the base, so that the position consistency of the container can be ensured, the relative position between the container and the electrode is not required to be adjusted before each infiltration, and the container can be prevented from being knocked by the electrode.

Description

Electrode clamping device for liquid interaction

Technical Field

The invention relates to the technical field of liquid interaction, in particular to an electrode clamping device for liquid interaction.

Background

In the field of neuroscience experiments, for multichannel silicon electrodes used in vivo electrophysiology, an immersion liquid operation is often required before recording to dye, and after recording is finished, an immersion liquid operation is still required to complete a cleaning process.

In the prior art, experimental staff is used for carrying out liquid infiltration operation by holding the electrode, and because the silicon electrode is transparent in color, fragile in structure and high in price, the electrode is easily damaged in a collision or even broken way, the experimental progress is affected, and the experimental cost is increased.

Disclosure of Invention

The invention aims to provide an electrode clamping device for liquid interaction, which is used for avoiding electrode damage and improving experimental efficiency.

In order to achieve the above object, the following technical scheme is provided:

an electrode gripping apparatus for liquid interaction, comprising:

a base;

the upright post is fixedly arranged on the base;

the container is fixedly arranged on the base;

the clamping rod is provided with a fixing part which is used for being connected with the mounting part of the electrode so as to fix the electrode to the clamping rod;

the clamping head is detachably arranged on the upright post, the clamping rod is clamped on the clamping head and can slide along the clamping head, so that the electrode can extend into the container, the clamping head is provided with a clamping adjusting piece, and the clamping adjusting piece is used for adjusting the clamping force of the clamping rod clamped by the clamping head.

As an alternative scheme of the electrode clamping device for liquid interaction, an included angle a is formed between the upright post and the top surface of the base, and the included angle a is an acute angle.

As an alternative to the electrode gripping means for liquid interaction, the gripping bar is of cylindrical construction.

As an alternative to the electrode clamping means for liquid interaction, the clamping bar has a first end and a second end opposite in its axial direction, the first end being clamped to the clamping head, the second end being provided with a mounting plane, the mounting plane being parallel to the axis of the clamping bar; the fixing part is arranged on the installation plane.

As an alternative to the electrode clamping device for liquid interaction, the fixing portion is a groove formed in the mounting plane.

As an alternative to the electrode clamping device for liquid interaction, the second end is further provided with an avoidance slope that is disposed corresponding to the mounting plane, so that the thickness b of the second end of the clamping rod gradually decreases from the first end to the second end along the axial direction of the clamping rod.

As an alternative scheme of the electrode clamping device for liquid interaction, one side of the upright post along the first direction is provided with an extension part, one end of the extension part is fixedly connected with the upright post, and the other end of the extension part is detachably connected with the clamping head.

As an alternative to electrode gripping means for liquid interaction, the inner diameter of the container gradually increases from the bottom of the container to the mouth.

As an alternative to the electrode gripping means for liquid interaction, the electrode gripping means for liquid interaction further comprises a reinforcing connection connected between the upright and the base.

As an alternative to the electrode clamping device for liquid interaction, the base, the upright and the container are integrally formed by 3D printing;

the chuck is manufactured through 3D printing;

the clamping bars are made by 3D printing.

Compared with the prior art, the invention has the beneficial effects that:

according to the electrode clamping device for liquid interaction, the electrode can be fixedly arranged on the clamping rod, the clamping rod is controlled to slide along the clamping head, so that the electrode stretches into the container and is contacted with the impregnating liquid contained in the container to be impregnated and dyed or cleaned, the clamping head is used for supporting the clamping rod, accidental shaking of hands of an experimenter can be effectively avoided, and the electrode is prevented from being knocked or broken, so that the electrode is protected; meanwhile, the clamping rod can be clamped by the clamping head through controlling the clamping adjusting piece, so that the electrode can be kept in the state after the electrode stretches into the container and is contacted with the infiltration liquid, an experimenter does not need to hold the electrode for a long time, and the electrode is further protected; the container is fixedly arranged on the base, so that the position consistency of the container can be ensured, the relative position between the container and the electrode is not required to be adjusted before each infiltration, the container can be prevented from being knocked by the electrode, and the experimental efficiency is improved.

Drawings

FIG. 1 is a schematic view of an electrode clamping device for liquid interaction according to an embodiment of the present invention;

FIG. 2 is a schematic diagram of a second embodiment of an electrode holder for liquid interaction;

FIG. 3 is a schematic view of a chuck according to an embodiment of the present invention;

fig. 4 is a schematic structural view of a clamping bar according to an embodiment of the present invention.

Reference numerals:

1. a base; 11. left side; 12. right side; 13. a front side; 14. a rear side;

2. a column; 21. an extension;

3. a chuck; 31. clamping the adjusting piece; 32a, a first clamping jaw; 32b, a second clamping jaw; 33. a clamping cavity; 331. arc-shaped clamping grooves;

4. a clamping rod; 41. a first end; 42. a second end; 43. a mounting plane; 44. a groove; 45. avoidance slope;

5. a container;

6. reinforcing the connection.

Detailed Description

For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments of the present invention. The components of the embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.

Thus, the following detailed description of the embodiments of the invention, as presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further definition or explanation thereof is necessary in the following figures.

In the description of the present invention, it should be noted that, directions or positional relationships indicated by terms such as "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., are directions or positional relationships based on those shown in the drawings, or are directions or positional relationships conventionally put in use of the inventive product, are merely for convenience of describing the present invention and simplifying the description, and are not indicative or implying that the apparatus or element to be referred to must have a specific direction, be configured and operated in a specific direction, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," "third," and the like are used merely to distinguish between descriptions and should not be construed as indicating or implying relative importance. In the description of the present invention, unless otherwise indicated, the meaning of "a plurality" is two or more.

In the description of the present invention, it should also be noted that, unless explicitly specified and limited otherwise, the terms "disposed", "connected" and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected or integrally connected; either mechanically or electrically. The specific meaning of the above terms in the present invention will be understood in specific cases by those of ordinary skill in the art.

In the present invention, unless expressly stated or limited otherwise, a first feature "above" or "below" a second feature may include both the first and second features being in direct contact, as well as the first and second features not being in direct contact but being in contact with each other through additional features therebetween. Moreover, a first feature being "above," "over" and "on" a second feature includes the first feature being directly above and obliquely above the second feature, or simply indicating that the first feature is higher in level than the second feature. The first feature being "under", "below" and "beneath" the second feature includes the first feature being directly under and obliquely below the second feature, or simply means that the first feature is less level than the second feature.

Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below by referring to the drawings are illustrative only and are not to be construed as limiting the invention.

As shown in fig. 1-4, the embodiment provides an electrode clamping device for liquid interaction, which comprises a base 1, a stand column 2, a chuck 3, a clamping rod 4 and a container 5, wherein the stand column 2 is fixedly arranged on the base 1; the container 5 is fixedly arranged on the base 1 and used for containing impregnating liquid so as to carry out impregnating dyeing or cleaning on the electrode; the clamping rod 4 is provided with a fixing part which is used for being connected with the mounting part of the electrode so as to fix the electrode to the clamping rod 4; the clamping head 3 is detachably arranged on the upright 2, and the clamping head 3 is connected with the upright 2 by bolts, and the clamping rod 4 is clamped on the clamping head 3 and can slide along the clamping head 3 so that the electrode can extend into the container 5, and the clamping head 3 is provided with a clamping adjusting piece 31, wherein the clamping adjusting piece 31 is used for adjusting the clamping force of the clamping head 3 for clamping the clamping rod 4.

The electrode can be fixedly arranged on the clamping rod 4, the clamping rod 4 is controlled to slide along the clamping head 3, so that the electrode stretches into the container 5 and is contacted with the impregnating liquid contained in the container 5 to carry out impregnating dyeing or cleaning, the clamping head 3 is utilized to play a supporting role on the clamping rod 4, accidental shaking of hands of an experimenter can be effectively avoided, and the electrode is prevented from being knocked or broken, so that the electrode is protected; meanwhile, the clamping head 3 can clamp the clamping rod 4 by controlling the clamping adjusting piece 31, so that the electrode can be kept in the state after the electrode stretches into the container 5 and is contacted with the infiltration liquid, an experimenter does not need to hold the electrode for a long time, and the electrode is further protected; the container 5 is fixedly arranged on the base 1, so that the position consistency of the container 5 can be ensured, the relative position between the container 5 and the electrode does not need to be adjusted before each infiltration, the electrode can be prevented from colliding with the container 5, and the experimental efficiency is improved.

It should be noted that, during the electrophysiological experiment, it is often necessary to transfer the electrode and the experimental material attached thereto between different experimental apparatuses, and for convenience of operation, the chuck 3 and the column 2 are configured to be detachably connected, so that the chuck 3 can be matched with the different experimental apparatuses. When the electrode is required to be transferred, only the clamping head 3 is required to be detached, an experimenter holds the clamping head 3 to transfer the electrode to a target experimental device, then the clamping head 3 is installed on the target experimental device, and the whole electrode clamping device for liquid interaction is not required to be transferred, so that the electrode transfer device is more convenient and faster.

Optionally, the base 1, the upright post 2 and the container 5 are integrally formed through 3D printing; optionally, the collet 3 is made by 3D printing; alternatively, the clamping bar 4 is made by 3D printing. The base 1, the upright posts 2, the clamping heads 3, the clamping rods 4 and the container 5 are made of nonmetallic materials by 3D printing, so that the processing period is short, the cost is low, the processing precision is high, the assembly of each part is stable, and the effect of avoiding accidental collision of the electrodes can be achieved; meanwhile, electromagnetic interference can be isolated during recording, and the normal operation of the electrode is prevented from being influenced.

Optionally, the chuck 3 includes two oppositely disposed clamping jaws, and the two clamping jaws are disposed at intervals to form a clamping cavity 33 between the two clamping jaws, the clamping rod 4 is inserted into the clamping cavity 33, and the distance between the two clamping jaws is adjusted by the clamping adjusting member 31, so that the two clamping jaws are close to or far away from each other, and the purpose of clamping or loosening the clamping rod 4 can be achieved. When two jaws grip the clamping bar 4, the clamping bar 4 is fixed, i.e. cannot move relative to the chuck 3. When the clamping bars 4 are released by the two clamping jaws, the clamping bars 4 can be moved relative to the chuck 3 so that the electrodes mounted on the clamping bars 4 can be inserted into or withdrawn from the container 5.

In this embodiment, the clamping adjusting member 31 is a bolt, and for convenience of description, two clamping jaws are respectively denoted as a first clamping jaw 32a and a second clamping jaw 32b, one end of the bolt passes through the first clamping jaw 32a to be in threaded connection with the second clamping jaw 32b, and the head of the bolt can be abutted against the first clamping jaw 32a by rotating the bolt, so that the first clamping jaw 32a and the second clamping jaw 32b are close to each other to clamp the clamping rod 4; the first jaw 32a and the second jaw 32b are then released from the clamping bar 4 by rotating the bolt in opposite directions to control the movement of the clamping bar 4 relative to the chuck 3.

Optionally, an included angle a is formed between the upright post 2 and the top surface of the base 1, and a is an acute angle. In other words, the upright post 2 is obliquely arranged on the base 1, so that an experimenter can observe the state of the surface of the tip of the electrode by using equipment such as a microscope, for example, whether brain tissues are cleaned, whether dye is attached, and the like, and plays a role in avoiding the equipment such as the microscope.

In this embodiment, the included angle a between the upright post 2 and the top surface of the base 1 is 30 °, which not only can meet the requirements of equipment such as avoidance microscope, but also is beneficial for the electrode to extend into the container 5 and avoid the collision between the electrode and the container 5.

Optionally, the clamping rod 4 has a cylindrical structure, and the clamping rod 4 can be rotated to adjust the phase position relationship between the electrode and the container 5, so that the fixing part of the clamping rod 4 is aligned with the mounting part of the electrode, and the assembly efficiency and the assembly precision of the electrode and the container are improved. Correspondingly, the two clamping jaws are provided with arc clamping grooves 331 matched with the cylindrical clamping rod 4, and the arc clamping grooves 331 of the two clamping jaws are oppositely arranged to form the clamping cavity 33 so as to ensure that the clamping rod 4 is stably clamped and the rotation of the clamping rod 4 is not influenced.

Optionally, the clamping bar 4 has a first end 41 and a second end 42 opposite in axial direction thereof, the first end 41 being clamped to the clamping head 3, the second end 42 being provided with a mounting plane 43, the mounting plane 43 being parallel to the axis of the clamping bar 4; the fixing portion is provided on the mounting plane 43. The electrode is fixedly arranged on the mounting plane 43, so that the connection stability of the electrode and the clamping rod 4 can be ensured, and the electrode falling off or accidental collision can be avoided.

Optionally, the fixing portion is a groove 44 formed on the mounting plane 43. It should be noted that, the mounting portion of the electrode is specifically a clamping protrusion, and the clamping protrusion is clamped with the groove 44, so that the electrode can be fixedly mounted on the clamping rod 4, and the operation is convenient.

Further, the second end 42 is further provided with an avoidance slope 45 corresponding to the installation plane 43, so that the thickness b of the second end 42 of the clamping rod 4 gradually decreases from the first end 41 to the second end 42 along the axial direction of the clamping rod 4, the avoidance slope 45 can avoid the container 5, the clamping rod 4 is prevented from colliding with the container 5, and the electrode damage is avoided.

Optionally, an extension part 21 is provided on one side of the upright 2 along the first direction, one end of the extension part 21 is fixedly connected with the upright 2, and the other end is detachably connected with the chuck 3. So set up for have certain distance between clamping bar 4 and the stand 2, be convenient for make electrode and clamping bar 4 assembly, and the problem that the electrode is easy to collide with stand 2 can not appear.

As shown in fig. 1, in the present embodiment, the base 1 has left and right sides 11 and 12 opposite in a first direction, and has front and rear sides 13 and 14 opposite in a second direction, which is perpendicular to the first direction. The bottom and the base 1 fixed connection of stand 2, and the top of stand 2 inclines to rear side 14, and extension 21 extends from stand 2 to the left side 11 of base 1, can effectively dodge equipment such as microscope, the state of experimental material of real-time observation in the experimental process of being convenient for.

Alternatively, the inner diameter of the container 5 is gradually increased from the bottom of the container 5 to the mouth, so that the electrode is convenient to extend into the container 5, and collision between the electrode and the container 5 can be avoided.

Optionally, the electrode clamping device for liquid interaction further comprises a reinforcing connection part 6, wherein the reinforcing connection part 6 is connected between the upright post 2 and the base 1 so as to ensure the connection stability of the upright post 2 and the base 1.

In this embodiment, the reinforcing connection portion 6 is a reinforcing block surrounding the connection portion between the upright post 2 and the base 1, and the reinforcing block, the base 1 and the upright post 2 are integrally formed together through 3D printing, so that on one hand, the connection strength between the upright post 2 and the base 1 is increased, and on the other hand, the weight of the base 1 is increased, and the problem that the electrode clamping device for liquid interaction falls down can be avoided.

Note that the above is only a preferred embodiment of the present invention and the technical principle applied. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, while the invention has been described in connection with the above embodiments, the invention is not limited to the embodiments, but may be embodied in many other equivalent forms without departing from the spirit or scope of the invention, which is set forth in the following claims.

Claims

1. An electrode-holding device for liquid interaction, comprising:

a base (1);

the upright post (2), the upright post (2) is fixedly arranged on the base (1);

the container (5) is fixedly arranged on the base (1);

a clamping rod (4), wherein the clamping rod (4) is provided with a fixing part which is used for being connected with an electrode mounting part so as to fix the electrode to the clamping rod (4);

the clamping head (3) is detachably arranged on the upright post (2), the clamping rod (4) is clamped on the clamping head (3) and can slide along the clamping head (3) so that the electrode can extend into the container (5), the clamping head (3) is provided with a clamping adjusting piece (31), and the clamping adjusting piece (31) is used for adjusting the clamping force of the clamping head (3) for clamping the clamping rod (4);

an included angle a is formed between the upright post (2) and the top surface of the base (1), and the included angle a is an acute angle; the included angle a not only can avoid microscope equipment, but also is beneficial for the electrode to extend into the container (5) and avoid collision between the electrode and the container (5).

2. Electrode clamping device for liquid interactions according to claim 1, characterized in that the clamping bar (4) is of cylindrical structure.

3. Electrode clamping device for liquid interactions according to claim 1, characterized in that the clamping bar (4) has a first end (41) and a second end (42) opposite in its axial direction, the first end (41) being clamped to the clamping head (3), the second end (42) being provided with a mounting plane (43), the mounting plane (43) being parallel to the axis of the clamping bar (4); the fixing portion is provided on the mounting plane (43).

4. An electrode gripping device for liquid interactions according to claim 3, characterized in that the fixing part is a groove (44) open in the mounting plane (43).

5. An electrode gripping arrangement for liquid interactions according to claim 3, characterized in that the second end (42) is further provided with a relief slope (45) arranged in correspondence of the mounting plane (43) so that the thickness b of the second end (42) of the clamping bar (4) decreases gradually in the axial direction of the clamping bar (4) from the first end (41) to the second end (42).

6. Electrode clamping device for liquid interaction according to claim 1, characterized in that one side of the upright (2) in the first direction is provided with an extension (21), one end of the extension (21) is fixedly connected with the upright (2) and the other end is detachably connected with the chuck (3).

7. Electrode gripping means for liquid interactions according to claim 1, characterized in that the inner diameter of the container (5) increases gradually from the bottom of the container (5) to the mouth.

8. Electrode gripping device for liquid interactions according to claim 1, characterized in that it further comprises a reinforcing connection (6), said reinforcing connection (6) being connected between the upright (2) and the base (1).

9. Electrode gripping device for liquid interaction according to any of the claims 1-8, characterized in that the base (1), the upright (2) and the container (5) are integrally formed by 3D printing;

the chuck (3) is manufactured through 3D printing;

the clamping rod (4) is manufactured through 3D printing.