CN114768634A - In-vitro diagnostic reagent mixing equipment - Google Patents
In-vitro diagnostic reagent mixing equipment Download PDFInfo
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- CN114768634A CN114768634A CN202210499107.XA CN202210499107A CN114768634A CN 114768634 A CN114768634 A CN 114768634A CN 202210499107 A CN202210499107 A CN 202210499107A CN 114768634 A CN114768634 A CN 114768634A
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Abstract
The invention belongs to the technical field of mixing devices, and particularly relates to in-vitro diagnostic reagent mixing equipment which comprises a box body and a vibrating mechanism, wherein a clamping mechanism and a fixing frame are arranged on the inner wall of the box body from top to bottom, and the clamping mechanism is detachably connected with the box body; the fixing frame is provided with a plurality of transverse partition plates and a plurality of longitudinal partition plates, the transverse partition plates and the longitudinal partition plates form a fence-type structure, the transverse partition plates and the longitudinal partition plates are horizontally provided with a first spring, the tail ends of the first springs are fixedly connected with gaskets, and the gaskets surround an opening for placing a reagent tube; a supporting plate is arranged below the fixing frame, the side wall of the supporting plate is abutted to the inner wall of the box body, and a plurality of placing seats are arranged on the supporting plate and correspond to the holes; be equipped with a plurality of trompils in the mount, can place a plurality of reagent bottles, can mix even a plurality of external diagnostic reagent at every turn through the vibrator, improved mixing efficiency.
Description
Technical Field
The invention relates to the technical field of mixing devices, in particular to in-vitro diagnostic reagent mixing equipment.
Background
The in vitro diagnostic reagent refers to a reagent, a kit, a calibrator, a quality control material, and the like, which can be used alone or in combination with an instrument, a device, or a system, and is used for in vitro detection of a human body sample (various body fluids, cells, tissue samples, and the like) in the prevention, diagnosis, treatment monitoring, prognosis observation, health status evaluation, and prediction of a genetic disease. The diagnostic reagent is prepared by adopting the principles or methods of immunology, microbiology, molecular biology and the like. The antibody immunodiagnostic reagent has the most varieties in the diagnostic kit, can be divided into infectious diseases, endocrine, tumor, drug detection, blood type identification and the like according to diagnosis categories, and most of the antibody immunodiagnostic reagent is in vitro diagnostic products, so that the in vitro diagnostic service demand rapidly rises along with the continuous progress of the income of residents and health consciousness, but when the in vitro diagnostic reagent is used for detection, the reagent needs to be fully contacted with a sample.
Chinese patent publication No. CN210045156U discloses an in vitro diagnostic reagent mixing device, which comprises a placing box, an elastic supporting mechanism with a lower end fixedly mounted on the bottom wall inside the placing box, and a fixed placing mechanism fixed with the upper end of the elastic supporting mechanism.
Disclosure of Invention
The present invention is directed to an in vitro diagnostic reagent mixing apparatus to solve the problems set forth in the background above.
In order to achieve the purpose, the invention provides the following technical scheme: an in vitro diagnostic reagent mixing device comprises a box body, wherein a clamping mechanism, a fixing frame, a supporting plate and a vibration structure are arranged on the inner wall of the box body from top to bottom, and the clamping mechanism is detachably connected with the box body;
the inner side wall of the fixing frame is provided with a plurality of transverse partition plates and a plurality of longitudinal partition plates, the transverse partition plates and the longitudinal partition plates form a grid structure, a plurality of springs I are arranged on two sides of all the transverse partition plates and two sides of each longitudinal partition plate, one end of each spring I is connected with the transverse partition plate or the longitudinal partition plate, the other end of each spring I is provided with a gasket, and the gaskets in each grid surround openings for placing reagent tubes;
the bottom wall of the supporting plate is connected with the vibration mechanism, a distance is reserved between the side wall of the supporting plate and the inner wall of the box body, a plurality of placing seats are arranged on the supporting plate, and the placing seats correspond to the holes one to one.
Preferably, grooves are formed in two opposite side walls of the box body, and an upright post is arranged on the bottom wall of each groove; clamping mechanism includes the apron, be equipped with solid fixed ring on the lateral wall of apron, gu fixed ring movable sleeve establish rather than the homonymy on the stand, just gu fixed ring goes up the spiro union have can with the holding screw of stand butt.
Preferably, the gasket is of an arc-shaped structure, and the circle center of the arc-shaped structure is located in the opening.
Preferably, a second opening is formed in the side wall of the box body and is located below the groove; the vibrating mechanism comprises two inserting plates and a vibrator, one end of each inserting plate is arranged on the side wall of the fixing frame, the other end of each inserting plate is movably provided with a fixing shaft, the fixing shaft penetrates through the inserting plates and can move relative to the fixing shaft, the fixing shaft is fixedly connected to the two opposite side walls of the second opening, and the side wall of the second opening, which is not provided with the fixing shaft, is connected with the inserting plates through a third spring; the vibrator is located on the bottom wall of the box body, the top wall of the vibrator is connected with the bottom wall of the supporting plate, and the vibrator is electrically connected with an external power supply.
Preferably, the volume of each grid in the grid-shaped structure is different in size.
Preferably, the bottom wall of the cover plate is provided with a plurality of grooves corresponding to the placing seats one to one.
Preferably, a second spring is connected between the gasket and the placing seat.
Compared with the prior art, the invention has the beneficial effects that:
1. according to the in-vitro diagnostic reagent mixing device provided by the invention, the fixing frame forms a fence-type structure, a plurality of reagent bottles can be placed, a plurality of in-vitro diagnostic reagents can be uniformly mixed each time by matching with the vibration mechanism, the mixing efficiency is improved, the in-vitro diagnostic reagent mixing device is suitable for immunodiagnostic reagents and other types of diagnostic reagents, and the working intensity of medical staff is reduced.
2. The in-vitro diagnostic reagent mixing equipment provided by the invention has the advantages that the reagent bottles with different sizes are stably fixed by matching the gasket, the placing seat and the cover plate, so that the in-vitro diagnostic reagent mixing equipment can be used for uniformly mixing different diagnostic reagents and samples, can also be used for uniformly mixing in-vitro diagnostic reagents, and avoids the phenomenon of uneven component distribution after long-time storage.
3. According to the in-vitro diagnostic reagent mixing device provided by the invention, the vibrator is matched with the first spring, the second spring and the third spring, so that the motion amplitudes of the reagent bottles are superposed, and the mixing efficiency is improved.
Drawings
FIG. 1 is a schematic structural diagram of an in vitro diagnostic reagent mixing apparatus provided in the present invention;
FIG. 2 is a diagram showing the positional relationship of the internal structure of the case;
FIG. 3 is a connection diagram of a first spring and transverse and longitudinal partition plates;
fig. 4 is a schematic structural view of the fixing frame.
Description of the reference numerals: 1. a box body; 2. a fixed mount; 3. a transverse partition plate; 4. a longitudinal partition plate; 5. a first spring; 6. a gasket; 7. a pallet; 8. a placing seat; 9. a groove; 10. a column; 11. a fixing ring; 12. tightening the screw; 13. a cover plate; 14. inserting plates; 15. a vibrator; 16. a second spring; 17. a second opening; 18. a fixed shaft; 19. a third spring; 20. and (5) opening holes.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in fig. 1, fig. 2, fig. 3 and fig. 4, the embodiment provides an in vitro diagnostic reagent mixing device, which includes a box 1, wherein a clamping mechanism, a fixing frame 2, a supporting plate 7 and a vibrating structure are arranged on an inner wall of the box 1 from top to bottom, and the clamping mechanism is detachably connected to the box 1;
a plurality of transverse partition plates 3 and a plurality of longitudinal partition plates 4 are arranged on the inner side wall of the fixing frame 2, the transverse partition plates 3 and the longitudinal partition plates 4 form a grid-shaped structure, a plurality of springs I5 are arranged on two sides of all the transverse partition plates 3 and the longitudinal partition plates 4, one ends of the springs I5 are connected with the transverse partition plates 3 or the longitudinal partition plates 4, gaskets 6 are arranged on the other ends of the springs I5, and the gaskets 6 in each grid surround an opening 20 for placing a reagent tube;
the bottom wall of the supporting plate 7 is connected with the vibration mechanism, a distance of 1cm-5cm is reserved between the side wall of the supporting plate 7 and the inner wall of the box body 1, a plurality of placing seats 8 are arranged on the supporting plate 7, and the placing seats 8 correspond to the holes one by one.
During the use, with external diagnostic reagent's reagent bottle place by in the mount 2 the gasket 6 surrounds in the trompil 20, the bottom of reagent bottle be located with trompil 20 one-to-one place on the seat 8, use behind the top of the fixed reagent bottle of clamping mechanism, start vibration mechanism, vibration mechanism drives the layer board 7 motion to the reagent bottle motion that the messenger is located and places on the seat 8 makes the reagent mix, simultaneously, spring 5 is connected gasket 6 works as when gasket 6 drives the motion of reagent bottle, because the effect of spring 5 makes the motion range of reagent bottle increase, thereby improves mixing efficiency carry out external diagnostic reagent's mixing in the box 1 and can avoid external influence to the mixed environment, provide relatively clear mixed environment for external diagnostic reagent.
In this embodiment, as shown in fig. 1, two opposite side walls of the box body 1 are provided with grooves 9, and a bottom wall of each groove 9 is provided with an upright post 10; the clamping mechanism comprises a cover plate 13, a fixing ring 11 is arranged on the side wall of the cover plate 13, the fixing ring 11 is movably sleeved on the upright post 10 on the same side of the fixing ring, and a set screw 12 capable of being abutted against the upright post 10 is screwed on the fixing ring 11; the clamping mechanism is connected with the box body 1 through the upright post 10; through holding screw 12 is realized clamping mechanism with the connection can be dismantled of cylinder 10, after putting reagent bottle, will gu 11 covers of fixed ring are established on the stand 10, work as when apron 13 compresses tightly reagent bottle, use holding screw 12 is fixed gu fixed ring 11, thereby fixed apron 13 is fixed reagent bottle.
In this embodiment, as shown in fig. 4, the gasket 6 is an arc-shaped structure, and the center of the arc-shaped structure is located in the opening 20; gasket 6 is for agreeing with the arc type structure of reagent bottle, laminating reagent bottle, better fixed reagent bottle.
In this embodiment, as shown in fig. 1, fig. 2 and fig. 4, a second opening 17 is provided on a side wall of the box body 1, and the second opening 17 is located below the groove 9; the vibrating mechanism comprises two inserting plates 14 and a vibrator 15, one end of each inserting plate 14 is arranged on the side wall of the fixed frame 2, a fixed shaft 18 is movably arranged at the other end of each inserting plate, the fixed shaft 18 penetrates through the inserting plates 14, the inserting plates 14 can move relative to the fixed shaft 18, specifically, the inserting plates 14 are provided with penetrating grooves along the length direction of the fixed shaft 18, the fixed shaft 18 penetrates into the penetrating grooves, the fixed shaft 18 is fixedly connected to the two opposite side walls of the opening II 17, and the side walls of the opening II 17, which are not provided with the fixed shaft 18, are connected with the inserting plates 14 through springs III 19; specifically, the fixed shaft 18 is fixedly connected with the front side wall and the rear side wall of the second opening 17, one end of a third spring 19 is arranged on the side wall of the inserting plate 14 in the vertical direction, and the other end of the third spring 19 is connected with the side wall of the second opening 17 in the vertical direction; the vibrator 15 is positioned on the bottom wall of the box body 1, the top wall of the vibrator 15 is connected with the bottom wall of the supporting plate 7, and the vibrator 15 is electrically connected with an external power supply; the mount 2 passes through the fixed axle 18 with 1 swing joint of box works as vibrator 15 during operation, wholly drives mount 2 motion, at this moment, spring three 19's elasticity has increased the motion degree of mount 2 to make the motion degree of reagent bottle strengthen, be favorable to improving the mixing efficiency of reagent.
In this embodiment, as shown in fig. 4, each grid in the grid structure has different volume sizes, and can be used for fixing reagent bottles with different sizes.
In this embodiment, as shown in fig. 1, the bottom wall of the cover plate 13 is provided with a plurality of grooves corresponding to the placing seats 8 one by one; after the reagent bottle is placed into the hole, the top of the reagent bottle is positioned in the groove, so that the reagent bottle is fixed.
In the present embodiment, as shown in fig. 2, a second spring 16 is connected between the pad 6 and the placing seat 8; two 16 springs are spacing to the reagent bottle on the one hand in vertical direction, prevent because apron 13 makes the reagent bottle aversion to the extrusion of reagent bottle, and on the other hand, because the top of reagent bottle is located in the recess, can make apron 13 not sticis the top of reagent bottle, the motion degree of two 16 spring multiplicable reagent bottles to improve the mixing effect.
Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that various changes in the embodiments and modifications of the embodiments or portions thereof may be made, and any changes, substitutions, improvements and the like made within the spirit and principle of the present invention should be included in the scope of the present invention.
Claims (7)
1. The in-vitro diagnostic reagent mixing equipment is characterized by comprising a box body (1), wherein a clamping mechanism, a fixing frame (2), a supporting plate (7) and a vibration structure are arranged on the inner wall of the box body (1) from top to bottom, and the clamping mechanism is detachably connected with the box body (1);
a plurality of transverse partition plates (3) and a plurality of longitudinal partition plates (4) are arranged on the inner side wall of the fixing frame (2), the transverse partition plates (3) and the longitudinal partition plates (4) form a grid-shaped structure, a plurality of springs I (5) are arranged on two sides of all the transverse partition plates (3) and the longitudinal partition plates (4), one end of each spring I (5) is connected with the transverse partition plates (3) or the longitudinal partition plates (4), a gasket (6) is arranged at the other end of each spring I, and the gaskets (6) in each grid surround to form an opening (20) for placing a reagent tube;
the bottom wall of the supporting plate (7) is connected with the vibration mechanism, a distance is reserved between the side wall of the supporting plate (7) and the inner wall of the box body (1), a plurality of placing seats (8) are arranged on the supporting plate (7), and the placing seats (8) are in one-to-one correspondence with the holes.
2. An in-vitro diagnostic reagent mixing device according to claim 1, characterized in that grooves (9) are arranged on two opposite side walls of the box body (1), and a column (10) is arranged on the bottom wall of each groove (9); clamping mechanism includes apron (13), be equipped with solid fixed ring (11) on the lateral wall of apron (13), gu fixed ring (11) movable sleeve establish rather than the homonymy on stand (10), just gu fixed ring (11) go up the spiro union have can with holding screw (12) of stand (10) butt.
3. An in-vitro diagnostic reagent mixing device according to claim 1, characterized in that the gasket (6) is of an arc-shaped structure, and the center of the arc-shaped structure is located in the opening (20).
4. The in-vitro diagnostic reagent mixing device according to claim 1, wherein the side wall of the box body (1) is provided with a second opening (17), and the second opening (17) is positioned below the groove (9); the vibrating mechanism comprises two inserting plates (14) and a vibrator (15), one end of each inserting plate (14) is arranged on the side wall of the fixing frame (2), a fixing shaft (18) is movably arranged at the other end of each inserting plate, the fixing shaft (18) penetrates through the inserting plates (14), the inserting plates (14) can move relative to the fixing shafts (18), the fixing shafts (18) are fixedly connected to two opposite side walls of the second opening (17), and the side walls, which are not provided with the fixing shafts (18), of the second opening (17) are connected with the inserting plates (14) through third springs (19); the vibrator (15) is located on the bottom wall of the box body (1), the top wall of the vibrator (15) is connected with the bottom wall of the supporting plate (7), and the vibrator (15) is electrically connected with an external power supply.
5. The in vitro diagnostic reagent mixing apparatus of claim 1 wherein the volume of each grid in the grid-like structure is different.
6. The in-vitro diagnostic reagent mixing device according to claim 1, characterized in that the bottom wall of the cover plate (13) is provided with a plurality of grooves corresponding to the placing seats (8) one by one.
7. An in-vitro diagnostic reagent mixing device according to claim 1, characterized in that a second spring (16) is connected between the gasket (6) and the placing seat (8).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210499107.XA CN114768634A (en) | 2022-05-09 | 2022-05-09 | In-vitro diagnostic reagent mixing equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210499107.XA CN114768634A (en) | 2022-05-09 | 2022-05-09 | In-vitro diagnostic reagent mixing equipment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114768634A true CN114768634A (en) | 2022-07-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210499107.XA Pending CN114768634A (en) | 2022-05-09 | 2022-05-09 | In-vitro diagnostic reagent mixing equipment |
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| Country | Link |
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| CN (1) | CN114768634A (en) |
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| CN207493613U (en) * | 2017-10-26 | 2018-06-15 | 广州市诺兰精细化工有限公司 | A kind of cosmetic material shakes mechanism |
| CN207951309U (en) * | 2018-01-24 | 2018-10-12 | 深圳市永佳农产品有限公司 | A kind of multi-purpose oscillator of speed governing |
| CN208250281U (en) * | 2018-03-27 | 2018-12-18 | 南京诺莱生物科技有限公司 | A kind of cause of disease tissue DNA extraction purification kit |
| EP3541517A1 (en) * | 2016-11-15 | 2019-09-25 | Biomérieux | Extraction system and method for extracting microorganisms contained in a sample |
| CN210356929U (en) * | 2019-04-29 | 2020-04-21 | 太原金域临床检验有限公司 | Multifunctional vortex mixer |
| CN214182806U (en) * | 2020-09-30 | 2021-09-14 | 中国医学科学院输血研究所 | Sample oscillation mixing device |
| CN215029154U (en) * | 2021-04-26 | 2021-12-07 | 复旦大学附属华山医院 | Test-tube rack for blood drawing |
| CN216296058U (en) * | 2021-10-21 | 2022-04-15 | 四川大学华西第二医院 | Intravenous medicine mixing and blending device |
| CN216433693U (en) * | 2021-08-27 | 2022-05-03 | 张勇 | Clinical laboratory uses reagent oscillation device |
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2022
- 2022-05-09 CN CN202210499107.XA patent/CN114768634A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3541517A1 (en) * | 2016-11-15 | 2019-09-25 | Biomérieux | Extraction system and method for extracting microorganisms contained in a sample |
| CN206863040U (en) * | 2017-06-23 | 2018-01-09 | 南京澳林生物科技有限公司 | A kind of good total bilirubin kit of sealing |
| CN207493613U (en) * | 2017-10-26 | 2018-06-15 | 广州市诺兰精细化工有限公司 | A kind of cosmetic material shakes mechanism |
| CN207951309U (en) * | 2018-01-24 | 2018-10-12 | 深圳市永佳农产品有限公司 | A kind of multi-purpose oscillator of speed governing |
| CN208250281U (en) * | 2018-03-27 | 2018-12-18 | 南京诺莱生物科技有限公司 | A kind of cause of disease tissue DNA extraction purification kit |
| CN210356929U (en) * | 2019-04-29 | 2020-04-21 | 太原金域临床检验有限公司 | Multifunctional vortex mixer |
| CN214182806U (en) * | 2020-09-30 | 2021-09-14 | 中国医学科学院输血研究所 | Sample oscillation mixing device |
| CN215029154U (en) * | 2021-04-26 | 2021-12-07 | 复旦大学附属华山医院 | Test-tube rack for blood drawing |
| CN216433693U (en) * | 2021-08-27 | 2022-05-03 | 张勇 | Clinical laboratory uses reagent oscillation device |
| CN216296058U (en) * | 2021-10-21 | 2022-04-15 | 四川大学华西第二医院 | Intravenous medicine mixing and blending device |
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