CN114703239B - Production method of allicin - Google Patents
Production method of allicin Download PDFInfo
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- CN114703239B CN114703239B CN202210289673.8A CN202210289673A CN114703239B CN 114703239 B CN114703239 B CN 114703239B CN 202210289673 A CN202210289673 A CN 202210289673A CN 114703239 B CN114703239 B CN 114703239B
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Abstract
The invention discloses a method for producing allicin, which relates to the technical field of medicines and has the advantages of effectively improving the yield of the allicin and solving the problem of odor, and the key points of the technical scheme are as follows: s1, soaking garlic in a fumaric acid solution, peeling, mashing, and adding the garlic into a first reactor provided with a stirring device; s2, adding cysteine and ethanol into the first reactor, and uniformly stirring; s3, transferring the uniformly stirred mixture into a second reactor, and leaching and carrying out enzymolysis; s4, separating the solid and liquid after the completion of the leaching and enzymolysis; s5, centrifuging, distilling and sterilizing the separated liquid to obtain the allicin.
Description
Technical Field
The invention relates to the technical field of medicines, in particular to a method for producing allicin.
Background
Allicin (allicin) is a general name of a class of sulfur-containing compounds in garlic, has a chemical name of trithio-dipropylene and is a main active ingredient generated by enzymolysis of alliin and allinase of the allicin in the garlic under certain conditions. The chemical structural formula is as follows:
as early as 1946, Raghunadana Rao et al demonstrated that the antibacterial activity of garlic is mainly the action of allicin. The diameter and the Minimum Inhibitory Concentration (MIC) of the allicin on each tested bacterium are measured, the allicin is found to have an antibacterial effect on Candida albicans, Staphylococcus aureus, Bacillus subtilis, Shigella dysenteriae, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus vulgaris, Pseudomonas aeruginosa and the like, and the allicin is shown to have an antibacterial effect on G + bacteria, G-bacteria and fungi. In addition, allicin also inhibits tubercle bacillus and pathogenic bacteria resistant to specific antibiotics, such as methicillin-resistant Staphylococcus aureus (MRSA) and the like.
However, the allicin has low extraction yield and obvious odor in the actual production process, which causes difficulty in subsequent application. Therefore, how to improve the yield of the allicin and solve the odor of the allicin is an urgent problem to be solved.
Disclosure of Invention
Aiming at the technical defects, the invention aims to provide a method for producing allicin, which can effectively improve the yield of the allicin and solve the problem of odor.
In order to solve the technical problems, the invention adopts the following technical scheme:
the invention provides a method for producing allicin, which comprises the following steps:
s1, soaking garlic in a fumaric acid solution, peeling, mashing, and adding the garlic into a first reactor provided with a stirring device;
s2, adding cysteine and ethanol into the first reactor, and uniformly stirring;
s3, transferring the uniformly stirred mixture into a second reactor, leaching and carrying out enzymolysis;
s4, separating the solid and liquid after the completion of the leaching and enzymolysis;
s5, centrifuging, distilling and sterilizing the separated liquid to obtain the allicin.
Preferably, the concentration of the fumaric acid solution is 2%, and the soaking time is 10-15 h;
the ethanol concentration is 65% -75%, and the feed-liquid ratio of garlic to ethanol is 1: 5-1: 8.
preferably, the stirring condition is that the stirring is carried out for 10-30 min at the temperature of 25-35 ℃;
the leaching enzymolysis condition is that leaching enzymolysis is carried out for 1-2 hours at 25-35 ℃.
Preferably, the first reactor includes an upward-opening mixing drum and a closed board for closing an opening of the mixing drum, a feeding drum is arranged on the closed board, a discharging pipe is arranged at the bottom of the mixing drum, a stop valve is arranged on the discharging pipe, a driving board is arranged on the closed board towards one side in the mixing drum, the driving board is connected with a U-shaped swing rod through a connecting piece in a rotating manner, a mixing rod extending into the mixing drum is connected to the swing rod in a rotating manner, and a first motor for driving the mixing rod to rotate is arranged on the swing rod.
Preferably, the connecting piece is including seting up the breach of keeping away from closing plate one end at the drive plate, it is connected with first bull stick to rotate on the relative mouthful wall of breach, fixed being equipped with on the first bull stick with first bull stick length direction vertically second bull stick, second bull stick and first bull stick are the cross, the both ends of pendulum rod rotate the both ends of connecting at the second bull stick respectively, be equipped with the first bull stick pivoted power spare of drive on the drive plate.
Preferably, the power member comprises a first gear coaxially and fixedly arranged on the outer wall of the first rotating rod and a first air cylinder arranged on the driving plate, and a first rack meshed with the first gear is fixedly connected to a piston rod of the first air cylinder.
Preferably, a second gear is coaxially fixed on the outer wall of the second rotating rod, a second cylinder is arranged on one side of the oscillating rod, a second rack meshed with the second gear is arranged on a piston rod of the second cylinder, and a guide plate for the second rack to slide is arranged on the outer wall of the oscillating rod on one side close to the second rack.
Preferably, the bottom of the stirring barrel is provided with an auxiliary piece for assisting stirring.
Preferably, the auxiliary part comprises a slide rail arranged at the bottom of the stirring cylinder, a slide block is connected in the slide rail in a sliding manner, the mixing drum is provided with a first rotating seat and a second rotating seat on both sides of the sliding rail, the height of the first rotating seat is lower than that of the second rotating seat, the first rotating seat is positioned at the bottom of the mixing drum, the second rotating seat is positioned at the wall of the mixing drum, the first rotating seat and the second rotating seat are respectively connected with a first stirring frame and a second stirring frame in a rotating way, the second stirring frame is positioned above the first stirring frame, the upper end of the sliding block is rotationally connected with a first guide block positioned in the first stirring frame, the upper end of the first guide block is rotationally connected with a second guide block positioned in a second stirring frame, the second guide block slides in the second stirring frame, first guide block slides in first stirring frame, the churn outer wall is equipped with the second motor of the first stirring frame pivoted of drive.
Preferably, a plurality of vertically upward power rods are arranged at the upper end of the second stirring frame along the periphery of the second stirring frame.
The invention has the beneficial effects that:
by adopting a synergistic pretreatment mode of soaking garlic in fumaric acid and adding cysteine, the odor of the garlic is effectively removed, and the subsequent utilization of the garlicin is favorably expanded;
the garlic is soaked in fumaric acid and cysteine is added for synergistic pretreatment, so that the garlic is extracted under a low-acidity condition, the stability of the garlicin is further improved, and meanwhile, the extraction rate of the garlicin is effectively improved by adopting a mode of combining stirring, leaching and enzymolysis, the extraction rate reaches 0.96%, and the garlic is suitable for industrial production.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic structural diagram of the present embodiment;
FIG. 2 is a schematic structural diagram of a mixing drum according to the present embodiment;
fig. 3 is a schematic structural diagram for embodying a driving board of the present embodiment;
fig. 4 is a schematic structural diagram for embodying the slide rail in this embodiment.
Description of reference numerals:
in the figure: 1. a mixing drum; 11. a closing plate; 12. a feeding cylinder; 121. a discharge pipe; 13. a drive plate; 131. a swing rod; 132. a stirring rod; 133. a first motor; 134. a notch; 135. a first rotating lever; 136. a second rotating rod; 14. a first gear; 141. a first cylinder; 142. a first rack; 143. a second gear; 144. a second cylinder; 145. a second rack; 146. a guide plate; 15. a slide rail; 151. a slider; 152. a first rotating base; 153. a second rotating base; 154. a first stirring frame; 155. a second stirring frame; 156. a first guide block; 157. a second guide block; 16. a power rod.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
A method for producing allicin comprises the following steps:
s1, soaking garlic in a fumaric acid solution, peeling, mashing, and adding the garlic into a first reactor provided with a stirring device;
s2, adding cysteine and ethanol into the first reactor, and uniformly stirring;
s3, transferring the uniformly stirred mixture into a second reactor, leaching and carrying out enzymolysis;
s4, separating the solid and liquid after the extraction and enzymolysis;
s5, centrifuging, distilling and sterilizing the separated liquid to obtain the allicin.
Example 1
A method for producing allicin comprises the following steps:
s1, soaking 5kg of garlic in 1L of 2% fumaric acid solution for 13h, peeling, mashing, and adding into a first reactor provided with a stirring device;
s2, adding 50g of cysteine and 6L of ethanol with the concentration of 70% into a first reactor, and stirring for 20min at 30 ℃ to uniformly stir the mixture;
s3, transferring the uniformly stirred mixture into a second reactor, and leaching and carrying out enzymolysis for 1.5h at the temperature of 30 ℃;
s4, separating the solid and liquid after the completion of the leaching and enzymolysis;
s5, centrifuging, distilling and sterilizing the separated liquid to obtain the allicin.
The obtained allicin has yield of 0.96% and remarkably reduced odor.
As shown in fig. 2 and fig. 3, the first reactor includes a mixing drum 1 with an upward opening and a closing plate 11 for closing the opening of the mixing drum 1, a feeding drum 12 is provided on the closing plate 11, a discharging pipe 121 is provided at the bottom of the mixing drum 1, a stop valve is provided on the discharging pipe 121, at this time, the discharging pipe 121 may be vertically downward, a plurality of vertical columns are provided at the bottom of the mixing drum 1, each vertical column supports the mixing drum 1, so that the mixing drum 1 is separated from the ground, a driving plate 13 is provided at one side of the closing plate 11 facing the inside of the mixing drum 1, the driving plate 13 is rotatably connected with a U-shaped swing rod 131 through a connecting member, a mixing rod 132 extending into the mixing drum 1 is rotatably connected to the swing rod 131, and a first motor 133 for driving the mixing rod 132 to rotate is provided on the swing rod 131. At this time, the first motor 133 and the stirring rod 132 are respectively located at both sides of the swing link 131. And when the mixing drum 1 is used, the liquid level in the mixing drum 1 cannot be higher than the height of the swing rod 131. The discharge port of the feeding pipe can extend to the lower part of the swing rod 131.
As shown in fig. 2 and fig. 3, the range of stirring by the stirring rod 132 is increased while the swing rod 131 is driven by the connecting member, at this time, the first motor 133 drives the stirring rod 132 to rotate, so that the stirring rod 132 stirs the material in the stirring cylinder 1, at this time, the outer wall of the stirring rod 132 is provided with a plurality of stirring blades, the connecting member is used in cooperation with the first motor 133, the stirring efficiency and the stirring range of the stirring rod 132 are increased, and the stirring cylinder 1 can stir the material uniformly.
As shown in fig. 2 and fig. 3, the connecting member includes a notch 134 formed at one end of the driving plate 13 far from the sealing plate 11, the notch 134 is rotatably connected to the wall opposite to the opening, the first rotating rod 135 is distributed far from the sealing plate 11, a second rotating rod 136 perpendicular to the length direction of the first rotating rod 135 is fixedly arranged on the first rotating rod 135, the second rotating rod 136 and the first rotating rod 135 are cross-shaped, two ends of the oscillating rod 131 are rotatably connected to two ends of the second rotating rod 136 respectively, and a power member for driving the first rotating rod 135 to rotate is arranged on the driving plate 13. The power component drives the first rotating rod 135 to rotate, so that the first rotating rod 135 drives the stirring rod 132 to swing through the second rotating rod 136, the stirring range of the stirring rod 132 is enlarged, and one end of the second rotating rod 136 swings in the notch 134 in the process.
As shown in fig. 2 and 3, the power member includes a first gear 14 coaxially and fixedly disposed on an outer wall of the first rotating rod 135, and a first cylinder 141 disposed on the driving plate 13, and a first rack 142 engaged with the first gear 14 is fixedly connected to a piston rod of the first cylinder 141. At this time, the piston rod of the first cylinder 141 drives the first rack 142 to move back and forth, so that the first rack 142 drives the first gear 14 to rotate forward and backward, and when the first gear 14 rotates forward and backward, the first rotating rod 135 also rotates forward and backward, so that the second rotating rod 136 on the first rotating rod 135 drives the stirring rod 132 on the oscillating rod 131 to oscillate back and forth in the stirring cylinder 1. The operation is convenient.
As shown in fig. 2 and 3, in order to further increase the stirring range of the stirring rod 132, a second gear 143 is coaxially fixed on an outer wall of the second rotating rod 136, a second cylinder 144 is disposed on one side of the swing rod 131, a second rack 145 engaged with the second gear 143 is disposed on a piston rod of the second cylinder 144, and a guide plate 146 for sliding the second rack 145 is disposed on an outer wall of the swing rod 131 on a side close to the second rack 145. At this time, since both ends of the swing link 131 are rotatably connected to both ends of the second rotating rod 136, when the second cylinder 144 drives the second rack 145 to reciprocate, the second rack 145 moves along the outer wall of the second gear 143, so that the swing link 131 rotates around the second rotating rod 136, and the stirring rod 132 also rotates around the second rotating rod 136. The guide plate 146 is used for guiding the movement of the second rack 145, so that the second rack 145 is engaged with the second gear 143.
As shown in fig. 4, in order to increase the agitation of the material at the bottom of the agitating drum 1, an auxiliary material for assisting the agitation is provided at the bottom of the agitating drum 1.
As shown in fig. 4, the auxiliary member includes a slide rail 15 disposed at the bottom of the mixing drum 1, a slide block 151 is slidably connected in the slide rail 15, the mixing drum 1 is provided with a first rotating seat 152 and a second rotating seat 153 on both sides of the slide rail 15, the first rotating seat 152 is lower than the second rotating seat 153, the first rotating seat 152 is located at the bottom of the mixing drum 1, the second rotating seat 153 is located at the wall of the mixing drum 1, the first rotating seat 152 and the second rotating seat 153 are respectively rotatably connected with a first mixing frame 154 and a second mixing frame 155, the second mixing frame 155 is located above the first mixing frame 154, the upper end of the slide block 151 is rotatably connected with a first guide block 156 located in the first mixing frame 154, the upper end of the first guide block 156 is rotatably connected with a second guide block 157 located in the second mixing frame 155, the second guide block 157 slides in the second mixing frame 155, the first guide block 156 slides in the first mixing frame 154, the outer wall of the mixing drum 1 is provided with a second motor for driving the first mixing frame 154 to rotate.
As shown in fig. 4, when the second motor drives the first stirring frame 154 to rotate, the first stirring frame 154 drives the first guide block 156 in the first stirring frame 154 to move along with the first stirring frame 154 when rotating, at this time, the first guide block 156 drives the slider 151 to slide in the slide rail 15 on one hand, and drives the second guide block 157 to move along with the first guide block 156 on the other hand, and the second stirring frame 155 is driven to rotate by the second guide block 157, at this time, the first stirring frame 154 and the second stirring frame 155 form a cross rotation, so as to stir the material accumulated at the bottom of the stirring barrel 1.
As shown in fig. 4, a plurality of power rods 16 are vertically and upwardly arranged at the upper end of the second agitator frame 155 along the periphery of the second agitator frame 155. The power rod 16 is arranged, so that the second stirring frame 155 drives the power rod 16 to move when rotating, and the stirring effect on the materials in the stirring cylinder 1 is facilitated.
Example 2
A method for producing allicin comprises the following steps:
s1, soaking 5kg of garlic in 1L of 2% fumaric acid solution for 10h, peeling, mashing, and adding into a first reactor provided with a stirring device;
s2, adding 50g of cysteine and 8L of 65% ethanol into a first reactor, and stirring for 10min at 35 ℃ to uniformly stir the mixture;
s3, transferring the uniformly stirred mixture into a second reactor, and leaching and carrying out enzymolysis for 1h at the temperature of 35 ℃;
s4, separating the solid and liquid after the completion of the leaching and enzymolysis;
s5, centrifuging, distilling and sterilizing the separated liquid to obtain the allicin.
The obtained allicin has yield of 0.94% and remarkably reduced odor.
Example 3
A method for producing allicin comprises the following steps:
s1, soaking 5kg of garlic in 1L of 2% fumaric acid solution for 15h, peeling, mashing, and adding into a first reactor provided with a stirring device;
s2, adding 50g of cysteine and 5L of 75% ethanol into a first reactor, and stirring for 30min at 25 ℃ to uniformly stir the mixture;
s3, transferring the uniformly stirred mixture into a second reactor, and leaching and carrying out enzymolysis for 2h at the temperature of 25 ℃;
s4, separating the solid and liquid after the completion of the leaching and enzymolysis;
s5, centrifuging, distilling and sterilizing the separated liquid to obtain the allicin.
The obtained allicin has yield of 0.93% and remarkably reduced odor.
Comparative example 1
A method for producing allicin comprises the following steps:
s1, soaking 5kg of garlic in 1L of 2% fumaric acid solution for 13h, peeling, mashing, and adding into a first reactor provided with a stirring device;
s2, adding 6L of ethanol with the concentration of 70% into the first reactor, and stirring for 20min at the temperature of 30 ℃ to ensure that the mixture is uniformly stirred;
s3, transferring the uniformly stirred mixture into a second reactor, and leaching and carrying out enzymolysis for 1.5h at the temperature of 30 ℃;
s4, separating the solid and liquid after the completion of the leaching and enzymolysis;
s5, centrifuging, distilling and sterilizing the separated liquid to obtain the allicin.
The obtained allicin has yield of 0.69%, and odor is slightly reduced.
Comparative example 2
A method for producing allicin comprises the following steps:
s1, peeling and mashing 5kg of garlic, and adding the garlic into a first reactor provided with a stirring device;
s2, adding 50g of cysteine and 6L of ethanol with the concentration of 70% into a first reactor, and stirring for 20min at 30 ℃ to uniformly stir the mixture;
s3, transferring the uniformly stirred mixture into a second reactor, and leaching and carrying out enzymolysis for 1.5 hours at the temperature of 30 ℃;
s4, separating the solid and liquid after the completion of the leaching and enzymolysis;
s5, centrifuging, distilling and sterilizing the separated liquid to obtain the allicin.
The obtained allicin has yield of 0.58% and little odor reduction.
Comparative example 3
A method for producing allicin comprises the following steps:
s1, peeling and mashing 5kg of garlic, and adding the garlic into a reactor;
s2, adding 6L of ethanol with the concentration of 70% into a reactor, and leaching and carrying out enzymolysis for 1.5h at the temperature of 30 ℃;
s3, after leaching, centrifuging, distilling and sterilizing to obtain the allicin.
The obtained allicin has yield of 0.30% and obvious odor.
Compared with the comparative examples 1-3, the embodiment 1 shows that the odor of the allicin can be obviously reduced by the synergistic pretreatment mode of soaking the garlic in the fumaric acid and adding the cysteine, the stability of the allicin is further increased by extracting the allicin from the garlic under the low-acid condition, and the extraction rate of the allicin is effectively improved by the mode of combining stirring with leaching enzymolysis.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.
Claims (8)
1. The production method of allicin is characterized by comprising the following steps:
s1, soaking garlic in a fumaric acid solution, peeling, mashing, and adding the garlic into a first reactor provided with a stirring device;
s2, adding cysteine and ethanol into the first reactor, and uniformly stirring;
s3, transferring the uniformly stirred mixture into a second reactor, leaching and carrying out enzymolysis;
s4, separating the solid and liquid after the completion of the leaching and enzymolysis;
s5, centrifuging, distilling and sterilizing the separated liquid to obtain allicin;
the concentration of the fumaric acid solution is 2%, and the soaking time is 10-15 h;
the concentration of the ethanol is 65-75%, and the ratio of the garlic to the ethanol is 1: 5-1: 8;
the stirring condition is that the mixture is stirred for 10-30 min at the temperature of 25-35 ℃;
the leaching enzymolysis condition is that leaching enzymolysis is carried out for 1-2 h at 25-35 ℃.
2. The method for producing allicin according to claim 1, wherein the first reactor comprises a mixing drum (1) with an upward opening and a closing plate (11) for closing the opening of the mixing drum (1), a feeding drum (12) is arranged on the closing plate (11), a discharging pipe (121) is arranged at the bottom of the mixing drum (1), a stop valve is arranged on the discharging pipe (121), a driving plate (13) is arranged on one side of the closing plate (11) facing the inside of the mixing drum (1), the driving plate (13) is rotatably connected with a U-shaped swing rod (131) through a connecting piece, a mixing rod (132) extending into the mixing drum (1) is rotatably connected to the swing rod (131), and a first motor (133) for driving the mixing rod (132) to rotate is arranged on the swing rod (131).
3. A method for producing allicin according to claim 2, wherein the connecting member comprises a notch (134) formed at one end of the driving plate (13) far from the closing plate (11), the notch (134) is rotatably connected with a first rotating rod (135) relative to the mouth wall, a second rotating rod (136) perpendicular to the length direction of the first rotating rod (135) is fixedly arranged on the first rotating rod (135), the second rotating rod (136) and the first rotating rod (135) are in a cross shape, two ends of the swing rod (131) are respectively rotatably connected with two ends of the second rotating rod (136), and a power member for driving the first rotating rod (135) to rotate is arranged on the driving plate (13).
4. A method for producing allicin according to claim 3, wherein the power member comprises a first gear (14) coaxially and fixedly arranged on the outer wall of the first rotating rod (135) and a first cylinder (141) arranged on the driving plate (13), and a first rack (142) meshed with the first gear (14) is fixedly connected to the piston rod of the first cylinder (141).
5. A method for producing allicin according to claim 4, wherein the second gear (143) is coaxially fixed on the outer wall of the second rotating rod (136), a second air cylinder (144) is arranged on one side of the swing rod (131), a second rack (145) meshed with the second gear (143) is arranged on the piston rod of the second air cylinder (144), and a guide plate (146) for the second rack (145) to slide is arranged on the outer wall of the swing rod (131) on the side close to the second rack (145).
6. A process for producing allicin according to claim 2 or 5, wherein the bottom of the agitating barrel (1) is provided with auxiliary members for assisting agitation.
7. The method for producing allicin according to claim 6, wherein the auxiliary member comprises a slide rail (15) disposed at the bottom of the mixing drum (1), the slide rail (15) is connected with a slide block (151) in a sliding manner, the mixing drum (1) is distributed with a first rotating seat (152) and a second rotating seat (153) at both sides of the slide rail (15), the first rotating seat (152) is lower than the second rotating seat (153), the first rotating seat (152) is located at the drum bottom of the mixing drum (1), the second rotating seat (153) is located at the drum wall of the mixing drum (1), the first rotating seat (152) and the second rotating seat (153) are respectively connected with a first mixing frame (154) and a second mixing frame (155) in a rotating manner, the second mixing frame (155) is located above the first mixing frame (154), the upper end of the slide block (151) is connected with a first guide block (156) located in the first mixing frame (154) in a rotating manner, the upper end of the first guide block (156) is rotatably connected with a second guide block (157) located in a second stirring frame (155), the second guide block (157) slides in the second stirring frame (155), the first guide block (156) slides in the first stirring frame (154), and the outer wall of the stirring drum (1) is provided with a second motor for driving the first stirring frame (154) to rotate.
8. A process for producing allicin according to claim 7, wherein the upper end of the second agitator frame (155) is provided with a plurality of vertically upward power bars (16) along the periphery of the second agitator frame (155).
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| CN103484233B (en) * | 2013-09-17 | 2015-03-04 | 暨南大学 | Method and device for preparing garlic oil with racemate alliin as raw materials |
| CN103757066A (en) * | 2013-12-06 | 2014-04-30 | 山东好当家海洋发展股份有限公司 | Deodorized garlicin extraction method |
| CN104630299A (en) * | 2015-03-03 | 2015-05-20 | 广东轻工职业技术学院 | Extraction method of odorless allicin |
| AU2017205880A1 (en) * | 2016-01-08 | 2018-06-28 | Inqpharm Group Sdn Bhd | Garlic compositions |
| CN106337070A (en) * | 2016-08-24 | 2017-01-18 | 徐金蝶 | Garlicin extraction method |
| CN106701851B (en) * | 2016-12-19 | 2018-10-02 | 陈增光 | A kind of extracting method of allicin |
| CN110461160B (en) * | 2017-03-30 | 2022-06-17 | 莫特迩公司 | Antimicrobial garlic composition |
| CN108342421A (en) * | 2018-02-11 | 2018-07-31 | 常德金德新材料科技股份有限公司 | A kind of allicin extracting method |
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