CN114673655A - Detection method - Google Patents

Detection method Download PDF

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Publication number
CN114673655A
CN114673655A CN202210444506.6A CN202210444506A CN114673655A CN 114673655 A CN114673655 A CN 114673655A CN 202210444506 A CN202210444506 A CN 202210444506A CN 114673655 A CN114673655 A CN 114673655A
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China
Prior art keywords
pump
liquid
speed
pump tube
reaction vessel
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CN202210444506.6A
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Inventor
郭琪琪
张福星
王光亮
肖育劲
胡鹍辉
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Shenzhen Yhlo Biotech Co Ltd
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Shenzhen Yhlo Biotech Co Ltd
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Priority to CN202210444506.6A priority Critical patent/CN114673655A/en
Publication of CN114673655A publication Critical patent/CN114673655A/en
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    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B51/00Testing machines, pumps, or pumping installations

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Reciprocating Pumps (AREA)

Abstract

The invention relates to a detection method for detecting the aging degree of a pump tube of a peristaltic pump, which comprises the following steps: under the condition that the peristaltic pump works at set power, the liquid suction speed of the pump tube when the aging degree of the pump tube reaches a critical value is taken as a reference critical speed; measuring the imbibition speed of the pump tube at the set power; and when the liquid suction speed is higher than the critical speed, judging that the aging degree of the pump pipe does not reach the critical value and the pump pipe does not need to be replaced; and when the liquid suction speed is less than or equal to the critical speed, judging that the aging degree of the pump tube reaches a critical value and the pump tube needs to be replaced. Therefore, the liquid suction speed of the pump pipe is accurately measured, the aging degree of the pump pipe can be accurately evaluated, and the detection precision of the aging degree of the pump pipe is finally improved. Meanwhile, the purpose of accurately evaluating the replacement cycle of the pump pipe can be achieved, and the pump pipe is ensured to be replaced at an accurate time point.

Description

Detection method
Technical Field
The invention relates to the technical field of medical instruments, in particular to a detection method.
Background
In the in vitro diagnostic industry, fluid is generally delivered by a peristaltic pump, and the pump tube may age over time, causing the peristaltic pump to fail to achieve its intended performance. Therefore, the pump tube needs to be replaced at a proper time after aging. The conventional method generally determines the aging degree of the pump pipe by experience, and generally considers that the pump pipe reaches a critical value of the aging degree within a set time, so that the pump pipe must be replaced when the service life of the pump pipe reaches the set time, and the set time can be one year or half year. However, considering that there is a difference in actual usage of the peristaltic pump, the aging degree of the pump tube reaches a critical value before the set time is reached, and this will affect the usage function of the peristaltic pump since the pump tube is not replaced within the set time. Or the pump tube is still not aged to a critical value after the set time is exceeded, which is not favorable for cost saving in view of the fact that the pump tube is replaced when the set time is reached. Therefore, how to improve the detection accuracy of the pump tube aging is a technical problem to be solved urgently by those skilled in the art.
Disclosure of Invention
The invention solves the technical problem of how to improve the detection precision of the aging degree of the pump pipe. The aging judgment of the pump pipe is completed by utilizing the existing device parts of the instrument on the premise of not increasing other device parts.
A method for detecting the degree of ageing of a pump tube of a peristaltic pump, comprising the steps of:
under the condition that the peristaltic pump works at set power, the liquid suction speed of the pump tube when the aging degree of the pump tube reaches a critical value is taken as a reference critical speed;
measuring the imbibition speed of the pump tube at the set power; and
when the liquid suction speed is higher than the critical speed, judging that the aging degree of the pump pipe does not reach the critical value and the pump pipe cannot be replaced; and when the liquid suction speed is less than or equal to the critical speed, judging that the aging degree of the pump tube reaches a critical value and the pump tube cannot be replaced.
In one embodiment, a liquid is sucked from a reaction vessel containing a liquid through the pump tube for a certain time T, the liquid is present in the reaction vessel after the time T, a liquid amount Q of the liquid sucked by the pump tube during the time T is obtained, and a liquid suction speed S of the pump tube is measured as Q/T.
In one embodiment, the liquid amount Q is a volume of liquid, a cylindrical reaction vessel with a constant bore is provided, an area of a bottom surface defining a boundary of an inner cavity portion of the reaction vessel is determined, and a volume of liquid sucked by the pump tube in the time T is determined by a difference in liquid level of the reaction vessel.
In one embodiment, the level difference of the reaction vessel is obtained by a level sensor.
In one embodiment, the reaction vessel is made cylindrical or prismatic.
In one embodiment, the imbibition rate is assumed to be S when the pump tube is completely unaged0The liquid suction rate of the pump tube after aging was measured as S and the degree of aging was recorded as Δ ═ S/S0The critical value of the degree of aging of the pump tube is denoted as ΔFaceWhen Δ is greater than ΔFaceIn time, the pump pipe does not need to be replaced; when Delta is less than or equal to DeltaFaceWhen necessary, the pump tube needs to be replaced.
In one embodiment, the threshold value ΔFaceThe value of (a) is in the range of 50% to 80%.
In one embodiment, the total amount of the liquid contained in the reaction container is equal to the total amount of the liquid which can be sucked by the pump pipe at the critical speed in the time T; under the condition that the duration time of suction of the pump pipe reaches the time T, when no liquid exists in the reaction container, judging that the aging degree of the pump pipe does not reach a critical value; and when the liquid still exists in the reaction container, judging that the aging degree of the pump pipe reaches a critical value.
Therefore, through the test mode, the liquid level detection of the liquid level sensor on the residual liquid in the reaction vessel can be omitted, whether the aging degree of the guide pipe reaches a critical value or not can be judged by directly observing whether the liquid exists in the reaction vessel through naked eyes, and then whether the pump pipe needs to be replaced or not is judged, so that the convenience and the working efficiency of the detection method are provided.
In one embodiment, the determination of the imbibition rate is performed by means of a unit already present in the detection device applying said peristaltic pump.
Therefore, the existing units in the detection device are fully utilized to accurately test the liquid suction speed of the pump tube, so that the aging degree of the pump tube is accurately evaluated finally, and other additional mechanisms except the detection device are not needed to test, so that the effect of effectively reducing the test cost of the detection method can be achieved. Meanwhile, the reaction container does not need to be transferred between different testing components in a reciprocating manner, so that liquid splashing and loss caused by shaking of the reaction container are avoided, the testing precision of the liquid suction speed and the evaluation precision of the aging degree of the pump pipe are improved, and the testing precision of the detection method is improved. And the time consumed by reciprocating transfer among different test components can be effectively avoided, so that the test efficiency of the liquid suction speed and the evaluation efficiency of the aging degree of the pump tube are improved, and finally the test cost of the detection method is further reduced.
In one embodiment, liquid is injected into the reaction vessel through a filling unit in the detection device; measuring the imbibition speed by a detection unit in the detection device; the pipetting speed is compared with the critical speed by a processing unit in the detection device.
One technical effect of one embodiment of the invention is that: when the imbibing speed is higher than the critical speed, the aging degree of the pump tube is judged not to reach the critical value and does not need to be replaced; when the liquid suction speed is less than or equal to the critical speed, the aging degree of the pump tube is judged to reach the critical value and needs to be replaced.
Therefore, the liquid suction speed of the pump pipe is accurately measured, the aging degree of the pump pipe can be accurately evaluated, and the detection precision of the aging degree of the pump pipe is finally improved. Meanwhile, the condition that the pump tube is not replaced when the aging degree of the pump tube reaches a critical value can be effectively avoided, and the situation that the pump tube continues to work to influence the working performance of the peristaltic pump due to the overlong replacement period is prevented. And the condition that the pump pipe is replaced when the aging degree of the pump pipe does not reach a critical value can be effectively avoided, and the situation that the maintenance cost of the peristaltic pump is influenced due to the fact that the replacement period of the pump pipe is too short is prevented. Therefore, the purpose of accurately evaluating the replacement period of the pump pipe can be achieved by accurately measuring the liquid suction speed of the pump pipe, the pump pipe is ensured to be replaced at an accurate time point, the peristaltic pump is finally ensured to meet the expected working performance, and the maintenance cost of the peristaltic pump is reasonably reduced.
Drawings
Fig. 1 is a process flow diagram of a detection method according to an embodiment.
Detailed Description
To facilitate an understanding of the invention, the invention will now be described more fully with reference to the accompanying drawings. Preferred embodiments of the present invention are shown in the drawings. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "inner", "outer", "left", "right" and the like as used herein are for illustrative purposes only and do not represent the only embodiments.
Referring to fig. 1, the detection method provided by an embodiment of the present invention is used to detect the aging degree of a pump tube of a peristaltic pump, and the peristaltic pump is used in a detection device in the field of in vitro diagnosis technology, that is, the detection device includes the peristaltic pump. Under the combined action of various factors such as the ambient temperature, the rotating speed of the peristaltic pump, the property of the liquid to be sucked and the like, the pump pipe is gradually aged along with the time. An important feature of the aging of the pump tube is that the flexibility of the pump tube is reduced, and for a pump tube with relatively high aging degree, the flexibility of the pump tube is relatively low, and when the pump tube is squeezed to suck the liquid, the volume of the liquid sucked by the pump tube per unit time is reduced, namely, the liquid suction speed of the pump tube is reduced. Therefore, in view of the fact that a certain correlation exists between the liquid suction speed of the pump tube and the aging degree of the pump tube, the aging degree of the pump tube can be accurately measured and determined by testing the liquid suction speed of the pump tube, namely, the aging degree of the pump tube is accurately grasped by a user by taking quantitative data as reference, and therefore the accuracy of the detection method on the aging degree of the pump tube is improved.
The detection device mainly tests samples in the reaction container, and mainly comprises a filling unit, a detection unit and a processing unit, wherein the filling unit can be used for adding samples or reagents and the like into the reaction container. The detection unit may be configured to detect a height at which the liquid level is located in the reaction vessel, thereby determining a content of the sample in the reaction vessel and a content of a mixed solution formed by both the sample and the reagent. The processing unit has a calculation function and a judgment function, so that various parameters are calculated, and corresponding conclusions are drawn according to the calculated parameters.
Referring to fig. 1, in some embodiments, the detection method mainly includes the following steps:
and S110, taking the imbibing speed of the pump tube when the aging degree of the pump tube reaches a critical value as a reference critical speed under the condition that the peristaltic pump works at a set power.
S120, measuring the liquid suction speed of the pump tube under the set power.
S130, when the imbibition speed is higher than the critical speed, judging that the aging degree of the pump tube does not reach the critical value and the pump tube cannot be replaced; when the liquid suction speed is less than or equal to the critical speed, the aging degree of the pump tube is judged to reach the critical value and the pump tube cannot be replaced.
Therefore, the key to this detection method is to measure the pipetting speed of the pump tube. Of course, during the process of measuring the imbibing speed, it is necessary to ensure that the peristaltic pump operates at a set power, that is, for the same catheter, the power and the rotation speed of the peristaltic pump are the same when the catheter is completely unaged and after the catheter is aged to a certain degree, and the composition of the imbibed fluid can be kept consistent. In other words, the imbibition rate of the catheter at the time of complete non-aging and after aging to some extent is determined by aspirating a liquid of the same composition under the same operating conditions of the peristaltic pump.
In some embodiments, a liquid is sucked from a reaction vessel containing a liquid through a pump tube for a certain time T, the liquid is present in the reaction vessel after the time T, a liquid amount Q of the liquid sucked by the pump tube during the time T is obtained, and a liquid suction speed S of the pump tube is measured as Q/T.
For example, for a test of the pipetting speed, the pipetting speed can be characterized as the volume of liquid that is pipetted by the pump tube per unit time. Therefore, a reaction vessel may be provided, and the reaction vessel may be a regular columnar body, or of course, the reaction vessel may have an irregular structure. For example, the reaction vessel may have a prismatic or cylindrical shape, and obviously, the diameter of the reaction vessel is always uniform along the axial direction of the reaction vessel. When the area of the bottom surface of the reaction vessel is determined, the change in volume in the reaction vessel can be determined from the change in the height of the liquid level in the reaction vessel.
Specifically, a cylindrical reaction vessel is taken as an example, and if the diameter of the bottom surface of the reaction vessel is D. In a first step, a sufficient amount of liquid is poured into the reaction vessel and the initial height H at which the liquid level is located in the reaction vessel is identified1Secondly, sucking a certain time T from the reaction container containing liquid through a pump pipe, and after the sucking time T, preferably ensuring that the reaction container still contains the liquid, wherein the liquid meets the test requirement after being sucked; and recording the initial height H of the liquid level formed by the residual liquid in the reaction vessel2. Thirdly, the total volume V of the liquid sucked by the pump pipe in the time T is calculated, and the total volume V is pi D2/4*(H1-H2) And T, the liquid suction speed S of the pump tube with certain aging degree is V/T. When the liquid suction speed S is obtained by the above method, the liquid suction speed S is higher than the critical speed SFaceIn time, the aging degree of the pump pipe is judged not to reach the critical value, namely, the pump pipe does not reach the replacement period, so that the pump pipe does not need to be replaced, and the use and maintenance cost of the peristaltic pump is prevented from being improved due to the fact that the pump pipe which can be continuously used is replaced in advance. When the liquid suction speed S is lowAt or equal to the critical speed SFaceIn the process, the aging degree of the pump pipe is judged to reach the critical value, namely the pump pipe reaches the replacement period, so that the pump pipe needs to be replaced, and the working performance of the peristaltic pump is prevented from being influenced by continuously using the pump pipe which objectively needs to be replaced.
The height of the liquid in the reaction vessel can be obtained by a liquid level sensor, and the liquid level sensor can measure the height by the principle of light reflection or ultrasonic reflection and absorption. For example, when measurement is performed by light reflection, the emission unit of the liquid level sensor emits infrared rays, which reach the liquid level and are reflected along the original path to be received by the reception unit of the liquid level sensor, and the distance between the liquid level sensor and the liquid level is determined by calculating the time difference between emission and recovery of the infrared rays. When the liquid level changes, the liquid level sensor can obtain the change value of the liquid level height, further obtain the change value of the volume, and finally obtain the liquid suction speed. Obviously, the distance between the liquid surface and the bottom surface of the reaction vessel, that is, the height of the liquid surface in the reaction vessel can also be obtained by calculation based on the distance between the liquid surface sensor and the liquid surface.
As another example, the imbibition speed S can be measured by the weight of liquid imbibed by the pump tube per unit time. In particular, in a first step, a sufficient quantity of liquid is injected into the reaction vessel, and the total weight G of the reaction vessel and the liquid is measured by a weighing device1. Secondly, sucking a certain time T from the reaction container containing liquid through a pump pipe, and after the sucking time T, preferably ensuring that the reaction container still contains the liquid, wherein the liquid meets the test requirement after being sucked; the total weight G of the reaction vessel and the remaining liquid is measured again by the weighing device2. Thirdly, the weight G of the liquid sucked by the pump pipe in the time T is calculated1-G2Therefore, for a pump tube with a certain degree of aging, the suction rate S of the pump tube is (G)1-G2) and/T. Similarly, when the liquid suction speed S is obtained by the above method, the liquid suction speed S is higher than the critical speed SFaceIn the method, the aging degree of the pump pipe is judged to be less than the critical value, and the pump pipe is not replacedAnd the pump pipe is not required to be replaced. When the liquid suction speed S is less than or equal to the critical speed SFaceAnd judging that the aging degree of the pump pipe reaches a critical value and the pump pipe reaches a replacement period, so that the pump pipe needs to be replaced.
In some embodiments, the imbibition rate S can be determined when the pump tube is completely unaged by the imbibition rate determination method described above0The liquid suction speed of the pump tube after aging is measured as S, and the degree of aging of the pump tube can be measured by Δ ═ S/S0To characterize. It is clear that the critical speed S of the suction of the pump tube at the critical aging level isFaceTherefore, the critical value of the aging degree of the pump tube is recorded as ΔFaceDelta of thisFace=SFace/S0. Therefore, when Δ is larger than ΔFaceIs, meaning S is greater than the critical speed SFaceAnd judging that the aging degree of the pump pipe does not reach the critical value, and the pump pipe does not reach the replacement period, so that the pump pipe does not need to be replaced. When Delta is less than or equal to DeltaFaceIs, it means that S is less than or equal to the critical speed SFaceIf so, the aging degree of the pump pipe is judged to reach the critical value, and the pump pipe reaches the replacement period, so that the pump pipe needs to be replaced.
In some embodiments, the pump tube degradation threshold ΔFaceIs in the range of 0 to 100%, e.g. critical value Δ of pump tube agingFaceIs in the range of 50% to 80%, e.g. the value ofFaceCan be 50%, 60%, 70% or 80%, and can be used for adjusting delta according to the practical condition of the working condition of the peristaltic pumpFaceThe value of (A) is reasonably adjusted, so that the replacement period of the pump pipe is reasonably adjusted.
In some embodiments, the total amount of the liquid contained in the reaction container is equal to the total amount of the liquid that can be sucked by the pump tube at the critical speed in the time T, and in the case that the duration of the suction by the pump tube reaches the time T, when no liquid exists in the reaction container, the aging degree of the pump tube is determined to have not reached the critical value, so that the pump tube does not need to be replaced. When liquid still exists in the reaction container, the aging degree of the pump pipe is judged to reach a critical value, so that the pump pipe needs to be replaced.
For example, for a pump tube that has reached a critical level of aging, the suction rate of the pump tube will be the critical rate. A first reaction vessel may be provided, a sufficient amount of liquid may be filled in the first reaction vessel, and then the liquid in the first reaction vessel may be sucked into an empty second reaction vessel through the pump tube. And after the pump pipe sucks time T, stopping the liquid suction work of the pump pipe, and measuring the height of the liquid level in the second reaction container through the liquid level sensor so as to obtain the volume of the liquid in the second reaction container. The volume of liquid in the second reaction vessel is the volume of liquid that the pump tube can draw in at the critical speed for the time T. Therefore, when the degree of deterioration of the pump tube needs to be measured, the liquid in the second reaction vessel can be sucked. When the aging degree of the pump tube does not reach the critical value, the liquid suction speed of the pump tube is higher than the critical speed, so that the pump tube can completely suck up the liquid in the second reaction vessel in the time T. When the aging degree of the pump tube reaches a critical value, the liquid suction speed of the pump tube is smaller than the critical speed, so that the pump tube cannot suck up the liquid in the second reaction vessel within the time T, and the liquid still exists in the second reaction vessel. Therefore, through this test mode, can omit liquid level sensor's detection, can be through whether there is liquid in the second reaction vessel of naked eye direct observation in order to judge whether the ageing degree of pipe reaches the critical value, and then judge whether need change the pump line to provide the convenience and the work efficiency of test.
As another example, for a pump tube that has reached a critical level of aging, the suction rate of the pump tube will be the critical rate. The empty first reaction vessel and the empty second reaction vessel may be provided, and after a sufficient amount of liquid is injected into the empty first reaction vessel, the weight of the empty second reaction vessel is determined by the loading device, and then the liquid in the first reaction vessel is sucked into the empty second reaction vessel by the pump tube. And after the pump pipe sucks the time T, stopping the liquid suction work of the pump pipe, and measuring the total weight of the second reaction container and the liquid in the second reaction container through a weighing device so as to calculate the weight of the liquid in the second reaction container. The weight of the liquid in the second reaction vessel is the weight of the liquid that the pump tube can suck in at the critical speed in the time T. Therefore, when the degree of deterioration of the pump tube needs to be measured, the liquid in the second reaction vessel can be sucked. When the aging degree of the pump tube does not reach the critical value, the liquid suction speed of the pump tube is higher than the critical speed, so that the pump tube can completely suck up the liquid in the second reaction vessel in the time T. When the aging degree of the pump tube reaches a critical value, the imbibition speed of the pump tube is less than the critical speed, so that the pump tube cannot suck up the liquid in the second reaction vessel within the time T, and the liquid still exists in the second reaction vessel. Therefore, through this test mode, can be through whether there is liquid in order to judge whether the ageing degree of pipe reaches the critical value in the second reaction vessel of naked eye direct observation, and then judge whether need change the pump line to improve the convenience and the work efficiency of test.
Therefore, with respect to the detection method in the above embodiment, in view of a certain correlation between the liquid suction speed of the pump tube and the aging degree of the pump tube, the liquid suction speed of the pump tube is accurately measured, so that the aging degree of the pump tube can be accurately evaluated, and the detection accuracy of the aging degree of the pump tube is finally improved. Meanwhile, the condition that the pump tube is not replaced when the aging degree of the pump tube reaches a critical value can be effectively avoided, and the situation that the pump tube continues to work to influence the working performance of the peristaltic pump due to the overlong replacement period is prevented. And the condition that the pump pipe is replaced when the aging degree of the pump pipe does not reach a critical value can be effectively avoided, and the maintenance cost of the peristaltic pump is prevented from being influenced due to the fact that the replacement period of the pump pipe is too short. Therefore, the purpose of accurately evaluating the replacement period of the pump pipe can be achieved by accurately measuring the liquid suction speed of the pump pipe, the pump pipe is ensured to be replaced at an accurate time point, the peristaltic pump is finally ensured to meet the expected working performance, and the maintenance cost of the peristaltic pump is reasonably reduced.
In some embodiments, the determination of the pipetting speed is performed by means of elements already present in the detection device. For example, by injecting the liquid into the reaction vessel by means of a filling unit, without the need to inject the liquid by means of an additional filling unit. The liquid-absorbing speed is also determined by the detecting unit without using other additional detecting units. The imbibing speed and the critical speed are also compared by the processing unit without using other additional processing units. Therefore, on the premise that no additional parts are added and only various units are arranged in the detection device, the liquid suction speed of the aged pump tube can be measured, so that the aging degree of the pump tube is accurately evaluated, and finally, a reliable reference basis is provided for a user to replace the pump tube.
Therefore, the existing units in the detection device are fully utilized to accurately test the liquid suction speed of the pump tube, so that the aging degree of the pump tube is accurately evaluated finally, and other additional mechanisms except the detection device are not needed to test, so that the effect of effectively reducing the test cost of the detection method can be achieved. Meanwhile, the reaction container does not need to be transferred between different testing components in a reciprocating manner, so that liquid splashing and loss caused by shaking of the reaction container are avoided, the testing precision of the liquid suction speed and the evaluation precision of the aging degree of the pump pipe are improved, and the testing precision of the detection method is improved. And the time consumed by reciprocating transfer among different test components can be effectively avoided, so that the test efficiency of the liquid suction speed and the evaluation efficiency of the aging degree of the pump tube are improved, and the test cost of the detection method is finally further reduced.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (10)

1. A method for detecting the degree of ageing of a pump tube of a peristaltic pump, characterized in that it comprises the following steps:
under the condition that the peristaltic pump works at set power, the imbibing speed of the pump tube when the aging degree of the pump tube reaches a critical value is taken as a reference critical speed;
measuring the imbibition speed of the pump tube at the set power; and
when the liquid suction speed is higher than the critical speed, judging that the aging degree of the pump pipe does not reach the critical value and the pump pipe does not need to be replaced; and when the liquid suction speed is less than or equal to the critical speed, judging that the aging degree of the pump tube reaches a critical value and the pump tube needs to be replaced.
2. The detection method according to claim 1, wherein the liquid is sucked from the reaction vessel containing the liquid through the pump tube for a certain period of time T, the liquid is present in the reaction vessel after the period of time T, a liquid amount Q of the liquid sucked from the pump tube is obtained for the period of time T, and a liquid suction speed S of the pump tube is measured as Q/T.
3. The detection method according to claim 2, wherein the liquid amount Q is a volume of liquid, a columnar reaction vessel having a constant bore is provided, an area of a bottom surface defining a boundary of an inner cavity portion of the reaction vessel is determined, and a volume of liquid sucked by the pump tube in the time T is measured by a difference in liquid level of the reaction vessel.
4. The detection method according to claim 3, wherein the level difference of the reaction vessel is obtained by a level sensor.
5. The detection method according to claim 3, wherein the reaction vessel is formed in a cylindrical or prismatic shape.
6. The detection method according to claim 1, wherein the detection signal is a signal,characterized in that the suction rate is S assuming that the pump tube is completely unaged0The liquid suction speed of the pump tube after aging was measured as S and the degree of aging was recorded as S/S0The critical value of the degree of aging of the pump tube is denoted as ΔFaceWhen Δ is greater than ΔFaceIn time, the pump pipe does not need to be replaced; when Delta is less than or equal to DeltaFaceWhen necessary, the pump tube needs to be replaced.
7. The detection method according to claim 6, wherein the threshold value Δ isFaceThe value of (a) is in the range of 50% to 80%.
8. The detection method according to claim 1, wherein the total amount of the liquid contained in the reaction vessel is made equal to the total amount of the liquid that can be taken up by the pump tube at the critical speed for the time T; under the condition that the duration time of suction of the pump pipe reaches the time T, when no liquid exists in the reaction container, judging that the aging degree of the pump pipe does not reach a critical value; and when the liquid still exists in the reaction container, judging that the aging degree of the pump pipe reaches a critical value.
9. The detection method according to claim 1, characterized in that the determination of the pipetting speed is carried out by using the elements already present in the detection device of the peristaltic pump.
10. The detection method according to claim 9, wherein the liquid is injected into the reaction vessel by an injection unit in the detection device; measuring the imbibition speed by a detection unit in the detection device; the pipetting speed is compared with the critical speed by a processing unit in the detection device.
CN202210444506.6A 2022-04-26 2022-04-26 Detection method Pending CN114673655A (en)

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CN213392609U (en) * 2020-09-17 2021-06-08 常州洛凯自动化技术有限公司 Gear pump aging test system

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US20140271106A1 (en) * 2013-03-13 2014-09-18 Agilent Technologies, Inc. Pump Testing for Predicting Lifetime and Wear Conditions
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