CN114668408B - Membrane potential data generation method and system - Google Patents

Membrane potential data generation method and system Download PDF

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CN114668408B
CN114668408B CN202210578181.0A CN202210578181A CN114668408B CN 114668408 B CN114668408 B CN 114668408B CN 202210578181 A CN202210578181 A CN 202210578181A CN 114668408 B CN114668408 B CN 114668408B
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membrane potential
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time
potential data
neuron
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CN114668408A (en
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曾一诺
尚德龙
周玉梅
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Zhongke Nanjing Intelligent Technology Research Institute
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • A61B5/377Electroencephalography [EEG] using evoked responses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7264Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • A61B5/7267Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems involving training the classification device

Abstract

The invention relates to a membrane potential data generation method and a membrane potential data generation system. The method comprises the steps of obtaining external stimulation information and a pulse at the previous moment; outputting membrane potential data at the current moment by using a neuron model according to external stimulation information; the process of the neuron model for outputting the membrane potential data at the current moment comprises the following steps: converting the external stimulation information from a time domain to a frequency domain with the first time-to-frequency converter; filtering the converted external stimulation information by using the membrane potential filter; converting the pulse at the previous moment from a time domain to a frequency domain by using the second time-frequency converter; filtering the converted pulse at the last moment by using the pulse filter; and outputting the membrane potential data of the current moment according to the filtered external stimulation information and the filtered pulse of the previous moment. The invention can improve the simulation precision of the membrane potential data.

Description

Membrane potential data generation method and system
Technical Field
The invention relates to the technical field of neuron simulation, in particular to a membrane potential data generation method and system.
Background
In recent years, development of brain-like computing, brain science, and deep learning is vigorous, and neurons are receiving close attention as the most basic unit. People hope to research related subjects such as intelligence and consciousness by researching the mechanism of biological neurons and simulating the network structure of the brain. The neuron receives an external stimulation signal, processes the external stimulation signal and transmits the external stimulation signal, and the process of simulating and constructing the neuron is a complex process, which not only can be helpful for understanding the operation mechanism of biological nerve cells, but also is beneficial for developing an artificial neural network algorithm with more biological interpretability.
FIG. 4 shows the mechanism of the biological neuron receiving the external stimulation signal, processing, and transmitting the membrane potential change and pulse generation of the biological neuron in the whole process, and the ordinate in FIG. 4 is the membrane potential/mV. In the absence of any external stimulus, the neuronal membrane potential is at resting potential. When receiving external stimuli, from a biological neurological perspective, the channels in the neuron membrane open and specific charged ions enter and exit the channels, resulting in a change in ion concentration inside and outside the neuron. The changes are shown in figure 4 as depolarization, repolarization and hyperpolarization of the neuronal membrane potential. When the membrane potential exceeds the neuron threshold by an external stimulus (such as a sudden strong stimulus or a continuous moderate stimulus), the neuron generates a pulse at that time, and then repolarization and hyperpolarization of the neuron membrane potential occur, i.e., the membrane potential rapidly drops below the resting potential and slowly rises back to the resting potential after a refractory period (absolute refractory period, relative refractory period) has elapsed. During the refractory period, the neurons experience diminished external stimuli, and any external stimuli have little effect on the membrane potential of the neuron.
The existing neuron model can only represent the activity mechanism of part types of neurons in the brain due to the design angle, and has no universality and universality. In addition, neuron models formed by differential equations, such as LIF models, Hodgkin-Huxley models, and Izhikevich models, contain a large number of hyper-parameters, and require experts to manually adjust the hyper-parameters by experience to simulate neuron-specific activity mechanisms, which is time-consuming and labor-consuming. The time-domain-based constructed neuron generation model, such as an impulse response model, and the point process model, require a large number of parameters, because each parameter corresponds to historical information of membrane potential and impulse. The more parameters, the higher the simulation accuracy. Reducing the number of parameters results in a drastic reduction in the simulation accuracy of the model, meaning that the model is not robust.
In order to facilitate deep understanding of the working mechanism of nerve cells and development of new artificial neural network algorithms and hardware circuits, a new simulation method and system are urgently needed.
Disclosure of Invention
The invention aims to provide a membrane potential data generation method and a membrane potential data generation system, which can improve the simulation precision of membrane potential data.
In order to achieve the purpose, the invention provides the following scheme:
a membrane potential data generating method comprising:
acquiring external stimulation information and a pulse at the previous moment; the external stimulus information includes: white noise at the current moment, and a membrane potential or a pulse input at the current moment;
outputting membrane potential data at the current moment by using a neuron model according to external stimulation information; the neuron model includes: the system comprises a first time-frequency converter, a membrane potential filter, a second time-frequency converter and a pulse filter; the process of the neuron model for outputting the membrane potential data at the current moment comprises the following steps:
converting the external stimulation information from a time domain to a frequency domain with the first time-to-frequency converter;
filtering the converted external stimulation information by using the membrane potential filter;
converting the pulse at the previous moment from a time domain to a frequency domain by using the second time-frequency converter;
filtering the converted pulse at the last moment by using the pulse filter;
and outputting the membrane potential data of the current moment according to the filtered external stimulation information and the filtered pulse of the previous moment.
Optionally, the converting, by using the first time-frequency converter, the external stimulation information from a time domain to a frequency domain specifically includes:
using formulas
Figure 728692DEST_PATH_IMAGE001
Determining the converted external stimulation information;
wherein the content of the first and second substances,
Figure 926455DEST_PATH_IMAGE002
the transformed external stimulus information received for neuron j,
Figure 865590DEST_PATH_IMAGE003
for the external stimulus information received by neuron j,
Figure 973355DEST_PATH_IMAGE004
is a Fourier basis function, t is the current time, and k is the term number of the Fourier basis function to the external stimulus.
Optionally, the filtering the converted external stimulation information by using the membrane potential filter specifically includes:
using formulas
Figure 977958DEST_PATH_IMAGE005
Determining filtered external stimulation information;
wherein the content of the first and second substances,
Figure 272804DEST_PATH_IMAGE006
in order to be the weight, the weight is,
Figure 624151DEST_PATH_IMAGE007
filtered external stimulus information for neuron j.
Optionally, the converting, by using the second time-frequency converter, the pulse at the previous time from the time domain to the frequency domain specifically includes:
using formulas
Figure 819378DEST_PATH_IMAGE008
Determining a pulse at the last moment after conversion;
wherein the content of the first and second substances,
Figure 965188DEST_PATH_IMAGE009
the pulse at the last time instant of neuron j,
Figure 511445DEST_PATH_IMAGE010
is a fourier basis function, t-1 is the last time,
Figure 73007DEST_PATH_IMAGE011
the pulse at the last time after the transition of neuron j,lis the number of terms of the fourier basis function for the pulse.
Optionally, the filtering, by using the pulse filter, the pulse at the last time after the conversion specifically includes:
using formulas
Figure 483260DEST_PATH_IMAGE012
Determining a pulse at a last time after filtering;
wherein the content of the first and second substances,
Figure 304366DEST_PATH_IMAGE013
for the last time pulse filtered by neuron j,
Figure 573805DEST_PATH_IMAGE014
are weights.
Optionally, the outputting, according to the filtered external stimulation information and the filtered pulse at the previous time, the membrane potential data at the current time includes:
using formulas
Figure 266954DEST_PATH_IMAGE015
Outputting the membrane potential data at the current moment;
wherein the content of the first and second substances,
Figure 905615DEST_PATH_IMAGE016
is the membrane potential data of the neuron j at the current moment,
Figure 393228DEST_PATH_IMAGE017
is the resting potential of neuron j.
A membrane potential data generating system comprising:
the data acquisition module is used for acquiring external stimulation information and a pulse at the previous moment; the external stimulus information includes: white noise at the current moment, and a membrane potential or a pulse input at the current moment;
the membrane potential data output module is used for outputting membrane potential data at the current moment by utilizing a neuron model according to external stimulation information; the neuron model includes: the system comprises a first time-frequency converter, a membrane potential filter, a second time-frequency converter and a pulse filter; the process of the neuron model for outputting the membrane potential data at the current moment comprises the following steps:
converting the external stimulation information from a time domain to a frequency domain with the first time-to-frequency converter;
filtering the converted external stimulation information by using the membrane potential filter;
converting the pulse at the previous moment from a time domain to a frequency domain by using the second time-frequency converter;
filtering the converted pulse at the last moment by using the pulse filter;
and outputting the membrane potential data of the current moment according to the filtered external stimulation information and the filtered pulse of the previous moment.
According to the specific embodiment provided by the invention, the invention discloses the following technical effects:
according to the membrane potential data generation method and system provided by the invention, a mechanism that a membrane potential filter and a pulse filter in a neuron model transmit information through oscillation is adopted, so that the activity mechanism of any neuron can be simulated; the mechanism that the neuron transmits signals in a specific frequency is utilized, the signals are converted from a time domain to a frequency domain, and high simulation precision is kept under a small number of parameters.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without inventive exercise.
FIG. 1 is a schematic flow chart of a method for generating membrane potential data according to the present invention;
FIG. 2 is a schematic diagram of a neuron model according to the present invention;
FIG. 3 is a schematic diagram of a membrane potential data generating system according to the present invention;
fig. 4 is a schematic diagram of a biological neuron receiving an external stimulus signal.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention aims to provide a membrane potential data generation method and a membrane potential data generation system, which can improve the simulation precision of membrane potential data.
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in further detail below.
Fig. 1 is a schematic flow chart of a film potential data generating method provided by the present invention, and as shown in fig. 1, the film potential data generating method provided by the present invention includes:
s101, acquiring external stimulation information and a pulse at the previous moment; the external stimulus information includes: white noise at the current moment, and a membrane potential or a pulse input at the current moment;
wherein the external stimulus information may be determined by the following formula:
Figure 9017DEST_PATH_IMAGE018
Figure 473234DEST_PATH_IMAGE019
wherein the content of the first and second substances,
Figure 592500DEST_PATH_IMAGE020
is a white noise source, and is,
Figure 719856DEST_PATH_IMAGE021
is the membrane potential of the neuron i,
Figure 557362DEST_PATH_IMAGE022
is the pulse of neuron i.
Figure 825270DEST_PATH_IMAGE023
Is the membrane potential of neuron i
Figure 64622DEST_PATH_IMAGE024
Or impulse of neuron i
Figure 362879DEST_PATH_IMAGE025
Because the importance of the membrane potential information transferred to neuron j by each neuron i is different, the weights are required to be determined by the weights
Figure 321302DEST_PATH_IMAGE026
To indicate. m is i Is white noise
Figure 628787DEST_PATH_IMAGE020
The weight of (c). White noise exists in the brain all the time, the white noise is not meant to be a nuisance, and a certain degree of white noise can be helpful for information transfer between neurons. In the formula, the white noise that is beneficial corresponds to a larger weight, and the white noise that is harmful corresponds to a smaller weight.
Figure 722645DEST_PATH_IMAGE023
And m i Calculated by the Hubby criterion or STDP.
S102, outputting membrane potential data at the current moment by using a neuron model according to external stimulation information; as shown in fig. 2, the neuron model includes: the system comprises a first time-frequency converter, a membrane potential filter, a second time-frequency converter and a pulse filter; the process of the neuron model for outputting the membrane potential data at the current moment comprises the following steps:
s201, converting the external stimulation information from a time domain to a frequency domain by using the first time-frequency converter;
s201 specifically includes:
using formulas
Figure 457383DEST_PATH_IMAGE027
Determining the converted external stimulation information;
wherein the content of the first and second substances,
Figure 768016DEST_PATH_IMAGE002
the transformed external stimulus information received for neuron j,
Figure 879191DEST_PATH_IMAGE028
for the external stimulus information received by neuron j,
Figure 827556DEST_PATH_IMAGE029
is a Fourier basis function, t is the current time, and k is the term number of the Fourier basis function to the external stimulus.
S202, filtering the converted external stimulation information by using the membrane potential filter;
s202 specifically includes:
using formulas
Figure 733195DEST_PATH_IMAGE030
Determining filtered external stimulation information; the membrane potential filter is a weighted summation operation aimed at emphasizing frequencies that are significant, while reducing the effect of unwanted frequencies. From a neurobiological point of view, most of the time, information is transferred between neurons by means of low frequency, which is lower in energy consumption and more energy-saving. The membrane potential filter takes advantage of this mechanism and gives large weight to specific frequencies, thereby emphasizing the effect of these frequencies.
Wherein the content of the first and second substances,
Figure 265545DEST_PATH_IMAGE006
the weight is obtained through an optimization algorithm containing L1 regularization, and the sparsity is realized;
Figure 914832DEST_PATH_IMAGE031
filtered external stimulus information for neuron j.
S203, converting the pulse at the previous moment from a time domain to a frequency domain by using the second time-frequency converter;
s203 specifically includes:
using formulas
Figure 717703DEST_PATH_IMAGE008
Determining after conversionA pulse at a previous time;
wherein the content of the first and second substances,
Figure 794244DEST_PATH_IMAGE009
the pulse at the last time instant of neuron j,
Figure 813890DEST_PATH_IMAGE010
is a fourier basis function, t-1 is the last time,
Figure 611076DEST_PATH_IMAGE032
the pulse at the last time after the transition of neuron j,lis the number of terms of the fourier basis function for the pulse. Theoretically, the number of terms of the Fourier basis function for external stimulation is infinite, the number of terms is determined according to the actual situation of the external stimulation or pulse, and the number of terms of the Fourier basis functions corresponding to the external stimulation and the pulse are different.
S204, filtering the converted pulse at the last moment by using the pulse filter;
the method specifically comprises the following steps:
using formulas
Figure 38427DEST_PATH_IMAGE012
Determining a pulse at a last time after filtering; the pulse filter is a weighted summation operation aimed at emphasizing frequencies that are significant, while reducing the effect of unwanted frequencies. From a neurobiological point of view, most of the time, information is transferred between neurons by means of low frequency, which is lower in energy consumption and more energy-saving. The impulse filter uses this mechanism to give large weight to specific frequencies, thereby emphasizing the effect of these frequencies.
Wherein the content of the first and second substances,
Figure 285869DEST_PATH_IMAGE013
for the last time pulse filtered by neuron j,
Figure 559855DEST_PATH_IMAGE014
for weighting, optimization calculation by regularization with L1The method is used for obtaining the product with sparseness.
And S205, outputting the membrane potential data of the current moment according to the filtered external stimulation information and the filtered pulse of the previous moment. The number of pulses of a neuron is related to the refractory period. If the number of pulses of a neuron increases over a period of time, the refractory period is correspondingly extended, i.e., the neuron is less likely to fire pulses. The refractory period of a neuron can explain pulse patterns with adaptive mechanisms, so the refractory period mechanism is indispensable for constructing a generic neuron model. Pulse of last moment
Figure 550945DEST_PATH_IMAGE013
Is incorporated into the model for revealing the refractory period mechanism of neurons.
S205 specifically includes:
using formulas
Figure 826943DEST_PATH_IMAGE033
Outputting the membrane potential data at the current moment;
wherein the content of the first and second substances,
Figure 510866DEST_PATH_IMAGE034
is the membrane potential data of the neuron j at the current moment,
Figure 475411DEST_PATH_IMAGE035
is the resting potential of neuron j.
Fig. 3 is a schematic structural diagram of a film potential data generating system provided by the present invention, and as shown in fig. 3, the film potential data generating system provided by the present invention includes:
a data acquisition module 301, configured to acquire external stimulation information and a pulse at a previous time; the external stimulus information includes: white noise at the current moment, and a membrane potential or a pulse input at the current moment;
a membrane potential data output module 302, configured to output membrane potential data at a current moment according to external stimulation information by using a neuron model; the neuron model includes: the system comprises a first time-frequency converter, a membrane potential filter, a second time-frequency converter and a pulse filter; the process of the neuron model for outputting the membrane potential data at the current moment comprises the following steps:
converting the external stimulation information from a time domain to a frequency domain with the first time-to-frequency converter;
filtering the converted external stimulation information by using the membrane potential filter;
converting the pulse at the previous moment from a time domain to a frequency domain by using the second time-frequency converter;
filtering the converted pulse at the last moment by using the pulse filter;
and outputting the membrane potential data of the current moment according to the filtered external stimulation information and the filtered pulse of the previous moment.
The artificial neural network model is constructed by adopting the method, and the constructed artificial neural network model is used for vehicle identification, face identification and language processing, so that the accuracy of the identification of the artificial neural network model is improved, and the calculated amount is reduced.
The impulse neural network is used as a third generation artificial neural network and is composed of biological neuron models. Compared with the current neural network, the impulse neural network has great advantages in complex data processing and energy consumption convenience. Specifically, thanks to the characteristics of the biological neuron model, the impulse neural network can process data containing a time domain and a space domain simultaneously, and meanwhile, information (with values of 0 and 1) is transmitted through impulses in the impulse neural network, so that compared with the traditional artificial neural network which transmits information by means of floating point numbers, the impulse neural network has the advantages that the required calculation amount is lower, and a large amount of energy consumption is saved.
As a third-generation artificial neural network, the impulse neural network has prominent expressions in various fields in recent years, such as object recognition, face recognition, natural language processing, brain-computer interface, and the like. Specifically, in the field of object recognition, the pulse neural network Spike-based BP SNN formed based on the LIF model obtains similar precision to that of the traditional artificial neural networks VGG and ResNet on MNIST, CIFAR-10 and SVHN data sets, and meanwhile, the calculation amount is lower.
The actual role of the biological neuron model has three aspects. (1) From the perspective of biological neurology and computational neurology, scientists understand the operation mechanism of biological neurons, the interaction mechanism among biological neurons, and the like through a biological neurology model, and also help to correct the defects of the existing biological neuron model by observing the mechanisms. (2) From the perspective of brain science and brain-like computing, in order to explore the mysteries of the brain and understand the relationship between the activities in the brain and human perception, movement and decision, electroencephalogram information such as brain-computer interfaces and the like is used for helping human beings, such as epilepsy treatment and the control of mechanical arms by disabled people. At present, a human brain map is made during key work, namely, each neuron in the human brain and the connection between the neurons are completely simulated through a computer, and the brain activity simulated by the computer is consistent with the human brain activity when any external stimulus is hoped to be applied. The neurons used in the human brain atlas are biological neuron models. (3) From the perspective of artificial neural networks, which are highly simplified models of biological neurons, are depopulated to computational neurology, with the neuron model being a simple weight multiplied by the input (W X), and collocated with the activation function. Originally limited by computer computing power in the last century, intact biological neurons were not used. At present, the artificial neural network has shown strong capability, and the application of the artificial neural network in various fields has excellent performance. However, the artificial neural network also has limitations, such as huge energy consumption, no inference capability, and the like. With the improvement of computer computing power, it is a great trend to replace the current highly simplified neurons with biological neurons in the artificial neural network, and it is hoped that the artificial neural network can save energy and obtain human-like reasoning ability.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. For the system disclosed by the embodiment, the description is relatively simple because the system corresponds to the method disclosed by the embodiment, and the relevant points can be referred to the method part for description.
The principles and embodiments of the present invention have been described herein using specific examples, which are provided only to help understand the method and the core concept of the present invention; meanwhile, for a person skilled in the art, according to the idea of the present invention, the specific embodiments and the application range may be changed. In view of the above, the present disclosure should not be construed as limiting the invention.

Claims (7)

1. A method of generating membrane potential data, comprising:
acquiring external stimulation information and a pulse at the previous moment; the external stimulus information includes: white noise at the current moment, and a membrane potential or a pulse input at the current moment;
outputting membrane potential data at the current moment by using a neuron model according to external stimulation information; the neuron model includes: the system comprises a first time-frequency converter, a membrane potential filter, a second time-frequency converter and a pulse filter; the process of the neuron model for outputting the membrane potential data at the current moment comprises the following steps:
converting the external stimulation information from a time domain to a frequency domain with the first time-to-frequency converter;
filtering the converted external stimulation information by using the membrane potential filter;
converting the pulse at the previous moment from a time domain to a frequency domain by using the second time-frequency converter;
filtering the converted pulse at the last moment by using the pulse filter;
and outputting the membrane potential data of the current moment according to the filtered external stimulation information and the filtered pulse of the previous moment.
2. The method for generating membrane potential data according to claim 1, wherein the converting the external stimulation information from a time domain to a frequency domain by using the first time-frequency converter specifically comprises:
using formulas
Figure 144161DEST_PATH_IMAGE001
Determining the converted external stimulation information;
wherein, the first and the second end of the pipe are connected with each other,
Figure 998985DEST_PATH_IMAGE002
the transformed external stimulus information received for neuron j,
Figure 981984DEST_PATH_IMAGE003
for the external stimulus information received by neuron j,
Figure 49298DEST_PATH_IMAGE004
is a Fourier basis function, t is the current time, and k is the term number of the Fourier basis function to the external stimulus.
3. The method for generating membrane potential data according to claim 2, wherein the filtering the converted external stimulation information by using the membrane potential filter specifically comprises:
using formulas
Figure 294029DEST_PATH_IMAGE005
Determining filtered external stimulation information;
wherein the content of the first and second substances,
Figure 54174DEST_PATH_IMAGE006
in order to be the weight of the weight,
Figure 993311DEST_PATH_IMAGE007
filtered external stimulus information for neuron j.
4. The method for generating membrane potential data according to claim 3, wherein the converting the pulse at the previous time from the time domain to the frequency domain by using the second time-frequency converter specifically comprises:
using formulas
Figure 395474DEST_PATH_IMAGE008
Determining a pulse at the last moment after conversion;
wherein, the first and the second end of the pipe are connected with each other,
Figure 500571DEST_PATH_IMAGE009
the pulse at the last time instant of neuron j,
Figure 697197DEST_PATH_IMAGE010
is a fourier basis function, t-1 is the last time,
Figure 389210DEST_PATH_IMAGE011
the pulse at the last time after the transition of neuron j,lis the number of terms of the fourier basis function for the pulse.
5. The method for generating membrane potential data according to claim 4, wherein the filtering the pulse at the last time after the conversion by using the pulse filter specifically comprises:
using formulas
Figure 63905DEST_PATH_IMAGE012
Determining a pulse at a last time after filtering;
wherein the content of the first and second substances,
Figure 23508DEST_PATH_IMAGE013
for the last time pulse filtered by neuron j,
Figure 391035DEST_PATH_IMAGE014
are weights.
6. The method for generating membrane potential data according to claim 5, wherein outputting membrane potential data at a current time according to the filtered external stimulation information and the filtered pulse at a previous time specifically comprises:
using formulas
Figure 304765DEST_PATH_IMAGE015
Outputting the membrane potential data at the current moment;
wherein the content of the first and second substances,
Figure 517571DEST_PATH_IMAGE016
is the membrane potential data of the neuron j at the current moment,
Figure 597261DEST_PATH_IMAGE017
is the resting potential of neuron j.
7. A membrane potential data generating system, comprising:
the data acquisition module is used for acquiring external stimulation information and a pulse at the previous moment; the external stimulus information includes: white noise at the current moment, and a membrane potential or a pulse input at the current moment;
the membrane potential data output module is used for outputting membrane potential data at the current moment by utilizing a neuron model according to external stimulation information; the neuron model includes: the system comprises a first time-frequency converter, a membrane potential filter, a second time-frequency converter and a pulse filter; the process of the neuron model for outputting the membrane potential data at the current moment comprises the following steps:
converting the external stimulation information from a time domain to a frequency domain with the first time-to-frequency converter;
filtering the converted external stimulation information by using the membrane potential filter;
converting the pulse at the previous moment from a time domain to a frequency domain by using the second time-frequency converter;
filtering the converted pulse at the last moment by using the pulse filter;
and outputting the membrane potential data of the current moment according to the filtered external stimulation information and the filtered pulse of the previous moment.
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