CN114655551B - Biological sample transport tank - Google Patents

Biological sample transport tank Download PDF

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Publication number
CN114655551B
CN114655551B CN202210337504.7A CN202210337504A CN114655551B CN 114655551 B CN114655551 B CN 114655551B CN 202210337504 A CN202210337504 A CN 202210337504A CN 114655551 B CN114655551 B CN 114655551B
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CN
China
Prior art keywords
sample
inactivation
inactivating
driving piece
section
Prior art date
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Active
Application number
CN202210337504.7A
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Chinese (zh)
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CN114655551A (en
Inventor
蔡乐瑾
邱智豪
吕季珮
张�杰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhejiang Unite Scientific Instrument Co ltd
Original Assignee
Zhejiang Unite Scientific Instrument Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Priority to CN202210337504.7A priority Critical patent/CN114655551B/en
Publication of CN114655551A publication Critical patent/CN114655551A/en
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • B65D25/10Devices to locate articles in containers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D85/00Containers, packaging elements or packages, specially adapted for particular articles or materials
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B67OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67BAPPLYING CLOSURE MEMBERS TO BOTTLES JARS, OR SIMILAR CONTAINERS; OPENING CLOSED CONTAINERS
    • B67B7/00Hand- or power-operated devices for opening closed containers
    • B67B7/38Power-operated cutting devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02WCLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
    • Y02W90/00Enabling technologies or technologies with a potential or indirect contribution to greenhouse gas [GHG] emissions mitigation
    • Y02W90/10Bio-packaging, e.g. packing containers made from renewable resources or bio-plastics

Abstract

The application provides a biological sample transportation tank, including sample holding chamber and inactivating agent holding chamber, driving piece and be connected in the cutting appearance subassembly and the inactivation subassembly of driving piece. The sample holding cavity is used for fixing the sample bottle, and the inactivating agent holding cavity is used for holding the inactivating bag, is equipped with the opening on the inactivating agent holding cavity, and inactivating agent holding cavity is linked together with the sample holding cavity through its opening. The sample cutting assembly is configured to rotate around a first rotation axis under the driving of the driving piece, the sample cutting assembly is further provided with a sample cutting device, the sample bottle is arranged on the rotation path of the sample cutting device, the inactivation assembly is connected with the driving piece and moves towards the opening along the direction parallel to the first rotation axis under the driving of the driving piece so as to squeeze the inactivation bag in the inactivation agent accommodating cavity, and the inactivation agent in the inactivation bag can overflow into the sample accommodating cavity through the opening, wherein the first rotation axis is parallel to the axis of the output shaft of the driving piece. The biological sample can be inactivated in time by controlling the driving piece.

Description

Biological sample transport tank
Technical Field
The application relates to the technical field of biological sample transportation safety, in particular to a biological sample transportation tank.
Background
In the transportation process of biological samples, certain accident hidden dangers exist at all times, especially when accidents such as loss, robbery and car accidents occur, if the biological samples out of control in the accidents such as loss, robbery and car accidents are not timely inactivated, serious biosafety results can be brought.
Disclosure of Invention
In view of the above problems, the present application provides a biological sample transportation tank, which can timely inactivate biological samples that are lost, stolen, robbed, car accident, etc., and out of control.
The application provides a biological sample transportation tank, including sample holding chamber and inactivating agent holding chamber, driving piece and be connected in the cutting appearance subassembly and the inactivation subassembly of driving piece. The sample containing cavity is used for fixing a sample bottle, and the inactivating agent containing cavity is used for containing an inactivating bag; the inactivating agent containing cavity is provided with an opening, and the inactivating agent containing cavity is communicated with the sample containing cavity through the opening of the inactivating agent containing cavity; the swatch assembly is configured to be rotatable about a first axis of rotation under the drive of the drive; the sample cutting assembly is also provided with a sample cutting device, and the sample bottle is arranged on a rotating path of the sample cutting device; the inactivation assembly is connected with the driving piece and moves towards the opening along the direction parallel to the first rotation axis under the driving of the driving piece so as to squeeze the inactivation bag in the inactivation agent accommodating cavity, so that the inactivation agent in the inactivation bag can overflow into the sample accommodating cavity through the opening; wherein the first axis of rotation is parallel to the axis of the output shaft of the drive.
Above-mentioned biological sample transport tank can cut the sample subassembly and rotate around first axis of rotation through the driving piece drive, cuts the appearance ware on the appearance subassembly and rotates around first axis of rotation thereupon this moment, and the sample bottle is located on the rotatory route of cutting the appearance ware, when cutting the appearance ware and when rotatory around first axis of rotation, can cut the sample bottle of sample holding intracavity, and then biological sample lets out from the sample bottle. In addition, the inactivation assembly is also connected with the driving piece so as to move along the direction parallel to the first rotation axis under the driving of the driving piece, and then the inactivation bag in the inactivation agent accommodating cavity is extruded, so that the inactivation agent in the inactivation bag can overflow into the sample accommodating cavity from the opening of the inactivation agent accommodating cavity. After the inactivating agent overflows into the sample containing cavity, the inactivating agent is fully mixed with the biological sample in the cut sample bottle, so that the biological sample inactivating treatment is realized. That is, the sample bottle is cut by the sample cutting assembly driven by the driving piece, and the inactivation bag is extruded and damaged and extruded into the sample accommodating cavity, so that the biological sample and the inactivating agent are fully mixed, and the aim of inactivation is fulfilled. The inactivation treatment of the biological sample which is out of control due to accident factors such as loss, robbery and car accident can be timely controlled by controlling the driving piece, so that the safety problem of the biological sample is ensured.
In some embodiments, the sample bottles are a plurality and the sample bottles are arranged in a circular array about the first axis of rotation; the sample cutter is positioned between two adjacent sample bottles.
In some embodiments, the sample cutting assembly comprises a fixed disk sleeved on the output shaft of the drive member; the inactivation assembly comprises a fixed barrel; the fixed disc comprises a transmission part and a rotation part; the transmission part is connected to the output shaft of the driving piece, and is matched with the fixed cylinder to convert the rotation motion of the transmission part into the linear motion of the fixed cylinder along the direction parallel to the first rotation axis; the rotating part is connected with and surrounds the transmission part, and the sample cutting device is fixedly connected with the fixed disc through the rotating part.
In some embodiments, the sample cutter is a heating wire, and the sample cutting assembly further comprises a first power supply electrically connected with the heating wire; wherein, the fusing temperature of heating wire is greater than the fusing point of sample bottle.
In some embodiments, a cutting blade is arranged at one end of the sample cutter away from the rotating part; the cutting blade is positioned between two adjacent sample bottles.
In some embodiments, the transmission part is provided with an internal thread, the axis of which coincides with the first rotation axis, the fixed cylinder is provided with a first section and a second section which are oppositely arranged along the direction of the first rotation axis, and the first section is provided with an external thread matched with the internal thread; the inactivation subassembly still includes the extrusion dish, the extrusion dish cover is located the second section of fixed section of section, just the extrusion dish is kept away from one side surface of first section is equipped with towards open-ended blade, so that the blade on the extrusion dish can be under the drive of fixed section of section is along being on a parallel with the direction of first axis of rotation removes and pierces the inactivation package of inactivating agent holding intracavity.
In some embodiments, a boss is provided on an outer surface of the stationary barrel between the first section and the second section, the inactivation assembly further comprising a stationary nut; the fixing nut is in threaded connection with the second section of the fixing barrel, so that the extrusion disc is fixed between the boss and the fixing nut.
In some embodiments, the inactivation group assembly further comprises a pre-tension spring; an abutting part extending inwards along the radial direction of the fixed cylinder is arranged at one end of the second section of the fixed cylinder, which is far away from the first section; one end of the pre-tightening spring is abutted with the transmission part of the fixed disc, and the other end of the pre-tightening spring is abutted with the abutting part so as to be compressively fixed between the transmission part and the abutting part.
In some embodiments, the biological sample transport tank further comprises a receiver and a controller; the receiver is configured to receive a manipulation instruction of the terminal device; the controller is communicatively coupled to the receiver, the controller being configured to control the drive member to output rotational torque in accordance with the manipulation instruction.
In some embodiments, the biological sample transport tank further comprises a second power source; the second power supply is in communication connection with the controller, and the second power supply is electrically connected with the driving piece.
The foregoing description is only an overview of the technical solutions of the present application, and may be implemented according to the content of the specification in order to make the technical means of the present application more clearly understood, and in order to make the above-mentioned and other objects, features and advantages of the present application more clearly understood, the following detailed description of the present application will be given.
Drawings
Various other advantages and benefits will become apparent to those of ordinary skill in the art upon reading the following detailed description of the preferred embodiments. The drawings are only for purposes of illustrating the preferred embodiments and are not to be construed as limiting the application. Also, like reference numerals are used to designate like parts throughout the accompanying drawings. In the drawings:
FIG. 1 is a cross-sectional view of a biological specimen transport canister in accordance with an embodiment of the present application;
FIG. 2 is a perspective view of a portion of the structure of a biological specimen transport canister in another embodiment of the application;
FIG. 3 is a block diagram of a holding pan and a holding cylinder of a biological specimen transport canister in accordance with an embodiment of the present application;
fig. 4 is a perspective view showing a partial structure of a biological sample transportation tank according to still another embodiment of the present application.
Reference numerals in the specific embodiments are as follows:
a sample receiving chamber 1, a sample bottle 11;
an inactivating agent containing chamber 2, an opening 21;
a driving member 3;
the sample cutting assembly 4, the sample cutting device 41, the fixed disc 42, the rotating part 421, the transmission part 422, the first power supply 43, the cutting blade 44 and the metal rod 45;
the inactivation assembly 5, the fixed drum 51, the boss 511, the abutment 512, the first section 513, the second section 514, the squeeze disk 52, the guide slot 521, the pretension spring 53, the fixation nut 54;
a receiver 6;
a controller 7;
a second power supply 8;
a housing 9, a guide projection 91.
Detailed Description
Embodiments of the technical solutions of the present application will be described in detail below with reference to the accompanying drawings. The following examples are only for more clearly illustrating the technical solutions of the present application, and thus are only examples, and are not intended to limit the scope of protection of the present application.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs; the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application; the terms "comprising" and "having" and any variations thereof in the description and claims of the present application and in the description of the figures above are intended to cover non-exclusive inclusions.
In the description of the embodiments of the present application, the technical terms "first," "second," etc. are used merely to distinguish between different objects and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated, a particular order or a primary or secondary relationship. In the description of the embodiments of the present application, the meaning of "plurality" is two or more unless explicitly defined otherwise.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment may be included in at least one embodiment of the present application. The appearances of such phrases in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. Those of skill in the art will explicitly and implicitly appreciate that the embodiments described herein may be combined with other embodiments.
In the description of the embodiments of the present application, the term "and/or" is merely an association relationship describing an association object, which means that three relationships may exist, for example, a and/or B may mean: a exists alone, A and B exist together, and B exists alone. In addition, the character "/" herein generally indicates that the front and rear associated objects are an "or" relationship.
In the description of the embodiments of the present application, the term "plurality" refers to two or more (including two), and similarly, "plural sets" refers to two or more (including two), and "plural sheets" refers to two or more (including two).
In the description of the embodiments of the present application, the orientation or positional relationship indicated by the technical terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. are based on the orientation or positional relationship shown in the drawings, and are merely for convenience of describing the embodiments of the present application and for simplifying the description, rather than indicating or implying that the apparatus or element referred to must have a specific orientation, be configured and operated in a specific orientation, and therefore should not be construed as limiting the embodiments of the present application.
In the description of the embodiments of the present application, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured" and the like are to be construed broadly and may be, for example, fixedly connected, detachably connected, or integrally formed; or may be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communicated with the inside of two elements or the interaction relationship of the two elements. The specific meaning of the above terms in the embodiments of the present application will be understood by those of ordinary skill in the art according to the specific circumstances.
As described in the background art, the concern of the biological sample transportation tank is generally its sealing performance and safety and stability. Typically, biological specimen transport tanks carrying biological specimens are required to withstand temperatures of-40 ℃ to +55 ℃ and internal pressures of up to 95 kPa. However, in the transportation process of biological samples, certain biological potential hazards easily exist, and especially when accidents such as loss, robbery and car accidents occur, serious biological safety consequences can be brought if the biological samples out of control in the accidents such as loss, robbery and car accidents are not timely inactivated.
Based on the above consideration, in order to ensure biosafety in the case of accidents such as loss, robbery and car accidents, which may occur in the transportation process of the biological sample transportation tank, the inventor has conducted intensive studies to design a biological sample transportation tank capable of performing self-inactivation treatment on the biological sample in the biological sample transportation tank when the biological sample transportation tank is lost, robbery and car accidents, and the like.
The biological sample transportation tank disclosed by the embodiment of the application can be used for storing and transporting the sample bottle of the biological sample, and can be applied to other high-risk articles needing safety guarantee and transported under the airtight condition.
Fig. 1 is a sectional view of a biological sample transport tank according to an embodiment of the present application, fig. 2 is a perspective view of a part of the biological sample transport tank according to another embodiment of the present application, fig. 3 is a structural view of a fixing plate and a fixing cylinder of the biological sample transport tank according to an embodiment of the present application, and fig. 4 is a perspective view of a part of the biological sample transport tank according to yet another embodiment of the present application.
Referring to fig. 1 to 4, according to some embodiments of the present application, a biological sample transport tank is provided, which includes a sample receiving chamber 1, an inactivating agent receiving chamber 2, a driving member 3, a sample cutting assembly 4 connected to the driving member 3, and an inactivating assembly 5. The sample holding cavity 1 is used for fixing a sample bottle 11, the inactivating agent holding cavity 2 is used for holding an inactivating bag, an opening 21 is arranged on the inactivating agent holding cavity 2, and the inactivating agent holding cavity 2 is communicated with the sample holding cavity 1 through the opening 21. The sample cutting assembly 4 is configured to rotate around a first rotation axis under the driving of the driving member 3, the sample cutting assembly 4 is further provided with a sample cutting device 41, the sample bottle 11 is arranged on the rotation path of the sample cutting device 41, the inactivation assembly 5 is connected with the driving member 3 to move towards the opening 21 along a direction parallel to the first rotation axis under the driving of the driving member 3 so as to squeeze the inactivation bag in the inactivation agent accommodating cavity 2, and the inactivation agent in the inactivation bag can overflow into the sample accommodating cavity 1 through the opening 21, wherein the first rotation axis is parallel to the axis of the output shaft of the driving member 3.
Specifically, when the inactivating assembly 5 presses the inactivating bag in the inactivating agent containing chamber 2, the inactivating bag is broken, and thus the inactivating agent overflows into the sample containing chamber 1 through the opening 21.
It will be appreciated that the sample assembly 4 is capable of rotating the cutter 41 about the first axis of rotation under the drive of the drive member 3 to sever a sample vial 11 located in the rotational path of the cutter 41 such that a biological sample solution flows from the sample vial 11. At the same time, the inactivating component 5 can move towards the opening 21 along the direction parallel to the first rotation axis under the drive of the driving piece 3 so as to squeeze the inactivating package in the inactivating agent containing cavity 2, so that the inactivating agent in the inactivating package can overflow into the sample containing cavity 1 through the opening 21. The driving piece 3 is adopted to drive the sample cutting assembly 4 and the inactivation assembly 5 to work simultaneously, so that the outflow of biological samples in the sample bottle 11 and the mixing of the inactivating agent in the inactivation bag and the biological samples can be realized simultaneously, and the aim of inactivation can be achieved efficiently. The inactivation of the biological sample which is out of control due to accident factors such as loss, robbery, car accident and the like can be timely controlled by controlling the driving piece 3, so that the safety problem of the biological sample is ensured.
In some embodiments, there are a plurality of sample bottles 11, and the plurality of sample bottles 11 are arranged in a circular array about the first axis of rotation, with the cutter 41 located between two adjacent sample bottles 11.
It will be appreciated that the sample bottles 11 are arranged in a circular array about the first axis of rotation, and that the sample cutter 41 is located between two adjacent sample bottles 11, such that all of the sample bottles 11 can be ruptured when the sample cutter 41 rotates about the first axis of rotation, and such that all of the biological samples in all of the sample bottles 11 can be ensured to be deactivated after the release of the inactivating agent.
In some embodiments, a sample cutter 41 is disposed between any two adjacent sample bottles 11, and this design can effectively improve the cutting efficiency of the sample bottles 11.
In some embodiments, the sample cutting assembly 4 comprises a fixed disk 42 that is sleeved on the output shaft of the driving member 3, the inactivating assembly 5 comprises a fixed cylinder 51, and the fixed disk 42 comprises a transmission portion 422 and a rotation portion 421. The transmission part 422 is connected to the output shaft of the driving member 3, and the transmission part 422 cooperates with the fixed cylinder 51 for converting the rotational movement of the transmission part 422 into a linear movement of the fixed cylinder 51 in a direction parallel to the first rotation axis. The rotary part 421 is connected to and surrounds the transmission part 422, and the cutter 41 is fixedly connected to the fixed disk 42 through the rotary part 421.
It will be appreciated that the transmission 422 of the fixed disc 42 is connected to the output shaft of the driving member 3 for rotation about the first axis of rotation under the drive of the driving member 3. And the transmission part 422 cooperates with the fixed cylinder 51 to convert the rotational movement of the fixed disk 42 about the first rotation axis into a linear movement in a direction parallel to the first rotation axis. The rotating portion 421 of the fixed disc 42 is fixedly connected with the sample cutter 41, so that the sample cutter 41 rotates around the first rotation axis under the drive of the rotating portion 421, and the sample bottle 11 is cut when needed.
In some embodiments, the sample cutter 41 is a heating wire, and the sample cutting assembly 4 further includes a first power supply 43 electrically connected to the heating wire. Wherein the fusing temperature of the heating wire is greater than the melting point of the sample bottle 11.
It will be appreciated that the fusing temperature of the heating wire is greater than the melting point of the sample bottle 11, so that the sample bottle 11 can be ensured to be sufficiently fused, so that the biological sample solution in the sample bottle 11 flows out.
In other embodiments, the end of the cutter 41 remote from the rotary portion 421 is provided with a cutting blade 44, the cutting blade 44 being located between two adjacent sample bottles 11.
It will be appreciated that the end of the sample cutter 41 away from the rotating portion 421 is provided with the cutting blade 44, so that the sample cutter 41 can smoothly cut the sample bottle 11 when rotating along with the rotating portion 421 of the fixed disk 42, and the biological sample solution in the sample bottle 11 flows out.
In some embodiments, the transmission 422 is provided with an internal thread, the axis of which coincides with the first axis of rotation, the fixed drum 51 being provided with a first section 513 and a second section 514, arranged opposite in the direction of the first axis of rotation, the first section 513 being provided with an external thread cooperating with the internal thread. The inactivating assembly 5 further comprises an extruding disc 52, the extruding disc 52 is sleeved on the second section 514 of the fixed barrel 51, and a blade facing the opening 21 is arranged on the surface of one side of the extruding disc 52 away from the first section 513, so that the blade on the extruding disc 52 can move along the direction parallel to the first rotation axis under the driving of the fixed barrel 51 and puncture the inactivating bag in the inactivating agent containing cavity 2.
It will be appreciated that the driving portion 422 of the fixed disk 42 is provided with an internal thread, and the first section 513 is provided with an external thread matching the internal thread, that is, the driving portion 422 of the fixed disk 42 is screwed with the first section 513 to mutually drive. When the fixed disk 42 rotates about the first rotation axis, the fixed cylinder 51 is driven to move linearly downward (in a direction parallel to the first rotation axis). The squeezing plate 52 is sleeved on the second section 514, and a blade facing the opening 21 is arranged on the surface of one side of the squeezing plate 52 away from the first section 513, and when the squeezing plate 52 moves along the direction parallel to the first rotation axis, the blade can puncture the inactivating bag in the inactivating agent containing cavity 2.
In some embodiments, the extruding plate 52 is provided with a plurality of through holes to communicate the inactivating agent containing cavity 2 and the sample containing cavity 1, so that when the inactivating agent in the inactivating agent containing cavity 2 is extruded, the inactivating agent can overflow into the sample containing cavity from the opening of the inactivating agent containing cavity 2 along the through holes.
In some embodiments, the surface of the pressing plate 52 near the first section 513 is provided with a plurality of accommodating grooves for accommodating sample bottles, and articles with adsorption force such as cotton can be placed in the accommodating grooves, so that the fixing stability of the sample bottles 11 is ensured, and the biological samples cannot pollute the biological sample transport tank when the biological samples are damaged.
In some embodiments, the outer surface of the fixed barrel 51 is provided with a boss 511 located between the first section 513 and the second section 514, and the inactivation assembly 5 further includes a fixing nut 54, the fixing nut 54 being threadably coupled to the second section 514 of the fixed barrel 51 such that the compression plate 52 is located between the boss 511 and the fixing nut 54.
That is, both the boss 511 and the fixing nut 54 limit the pressing plate 52 in a direction parallel to the first rotation axis, so that the pressing plate 52 can make a linear movement in a direction parallel to the first rotation axis under the movement of the fixing cylinder 51.
In some embodiments, the sample cutting assembly 4 further includes a first power source 43 and a metal rod 45 connected to the output shaft of the driving member 3, wherein one end of the metal rod 45 is electrically connected to the heating wire, and the other end of the metal rod 45 is electrically connected to the first power source 43 to form a current path.
It will be appreciated that the metal rod 45 is connected to the output shaft of the driving member 3 and is electrically connected to the heating wire and the first power source 43. Therefore, the metal rod 45 can rotate around the first rotation axis under the driving of the driving piece 3, so that the heating wire can be unfolded along the radial direction of the fixed disc 42, and a better fusing effect of the heating wire is ensured.
In some embodiments, the biological sample transportation tank further comprises a housing 9, the side of the squeeze disk 52 radially adjacent to the housing 9 is provided with a guide groove 521 extending in a direction parallel to the first rotation axis, and the housing 9 is provided with a guide protrusion 91 matching the guide groove 521.
It will be appreciated that the fixed disc 42, driven by the driving member 3, will rotate about the first axis of rotation, thereby moving the fixed cylinder 51 in a direction parallel to the first axis of rotation. When the pressing disc 52 and the shell 9 are fixed in a relative limiting way in the axial direction, the pressing disc 52 cannot rotate along with the fixed disc 42, and the fixed cylinder 51 is ensured to displace in the direction parallel to the first rotation axis under the driving of the fixed disc 42.
In some embodiments, the inactivation assembly 5 further comprises a pre-tension spring 53, one end of the second section 514 of the fixed barrel 51 remote from the first section 513 being provided with an abutment 512 extending radially inwardly of the fixed barrel 51, one end of the pre-tension spring 53 abutting the drive portion 422 of the fixed disc 42, the other end of the pre-tension spring 53 abutting the abutment 512 to be compressively secured between the drive portion 422 and the abutment 512.
It will be appreciated that the pretensioning spring 53 is placed in a compressed state in the fixed cylinder 51, with one end abutting against the transmission portion 422 of the fixed disk 42 and the other end abutting against the abutment portion 512. When the fixed disk 42 is driven to rotate by the driving room, the fixed cylinder 51 is driven to make linear motion along the direction parallel to the first rotation axis, and when the fixed cylinder 51 is rotated out of the fixed disk 42, the pretightening force of the pretightening spring 53 compressed between the transmission part 422 and the abutting part 512 is released, and the fixed disk is ejected toward the opening 21 of the inactivating agent containing chamber 2 along the direction parallel to the first rotation axis, and the pressing disk 52 is driven to make linear motion along the direction to press the inactivating bag. So that the inactivating bag is damaged, the inactivating agent in the inactivating bag overflows into the sample accommodating cavity 1, and then the inactivating agent is mixed with the biological sample solution, and the biological sample is inactivated.
In some embodiments, the biological sample transport tank further comprises a receiver 6 and a controller 7, the receiver 6 being configured to receive a manipulation instruction of the terminal device, the controller 7 being communicatively connected to the receiver 6, the controller 7 being configured to control the drive member 3 to output the rotational torque in accordance with the manipulation instruction.
Specifically, after the terminal device sends out the control instruction, the controller 7 controls the driving piece 3 to output the rotation torque according to the control instruction received by the receiver 6, and then drives the sample cutting assembly 4 and the inactivation assembly 5 to realize the functions of cutting the sample bottle 11 and squeezing the inactivation bag, so that the inactivation of the biological sample is controlled by the terminal device.
In some embodiments, the biological sample transport tank further comprises a second power source 8, the second power source 8 is communicatively coupled to the controller 7, and the second power source 8 is electrically coupled to the drive member 3. That is, the second power supply 8 can drive the driving member 3 to work under the control of the controller 7 to output a rotation moment so as to drive the sample cutting assembly 4 and the inactivation assembly 5 to perform related actions, thereby realizing the self-inactivation action of the biological sample in the biological sample transportation tank.
In some embodiments, the controller 7 is further electrically connected to the first power source 43, so that the first power source 43 controls the heating wire to emit heat under the control of the controller 7 to break the sample bottle 11.
In some embodiments, the biological sample transportation tank further includes a buzzer electrically connected to the receiver 6, and when the manipulation instruction received by the receiver 6 is an inactivation instruction, the buzzer sounds to indicate that the inactivation state is opened.
In some embodiments, the biological sample transport tank further comprises an indicator light electrically connected to the first power source 43 and the second power source 8, the indicator light being turned on when the power supply margin of the first power source 43 and the second power source 8 is less than the minimum power value.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present application, and not for limiting the same; although the present application has been described in detail with reference to the foregoing embodiments, it should be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit of the embodiments, and are intended to be included within the scope of the claims and description. In particular, the technical features mentioned in the respective embodiments may be combined in any manner as long as there is no structural conflict. The present application is not limited to the specific embodiments disclosed herein, but encompasses all technical solutions falling within the scope of the claims.

Claims (7)

1. A biological sample transport tank, the biological sample transport tank comprising:
the sample storage cavity is used for fixing a sample bottle, and the inactivating agent storage cavity is used for accommodating an inactivating bag; an opening is arranged on the inactivating agent containing cavity, and the inactivating agent containing cavity is communicated with the sample containing cavity through the opening of the inactivating agent containing cavity;
a drive member and a swatch assembly connected to the drive member, the swatch assembly configured to be rotatable about a first axis of rotation under the drive of the drive member; the sample cutting assembly is also provided with a sample cutting device, and the sample bottle is arranged on a rotating path of the sample cutting device; and
the inactivating component is connected with the driving piece and used for moving towards the opening along the direction parallel to the first rotation axis under the driving of the driving piece so as to squeeze the inactivating bag in the inactivating agent containing cavity, so that the inactivating agent in the inactivating bag can overflow into the sample containing cavity through the opening;
wherein the first axis of rotation is parallel to the axis of the output shaft of the drive;
the sample cutting assembly comprises a fixed disc sleeved on an output shaft of the driving piece; the inactivation assembly comprises a fixed barrel; the fixed disk includes:
the transmission part is connected to the output shaft of the driving piece and is matched with the fixed cylinder to convert the rotation motion of the transmission part into the linear motion of the fixed cylinder along the direction parallel to the first rotation axis;
the rotating part is connected with and surrounds the transmission part, and the sample cutting device is fixedly connected with the fixed disc through the rotating part;
the transmission part is provided with an internal thread, the axis of which coincides with the first rotation axis, the fixed cylinder is provided with a first section and a second section which are oppositely arranged along the direction of the first rotation axis, and the first section is provided with an external thread matched with the internal thread;
the inactivation assembly further comprises an extrusion disc, the extrusion disc is sleeved on the second section of the fixed cylinder, and a blade facing the opening is arranged on the surface of one side of the extrusion disc, which is far away from the first section, so that the blade on the extrusion disc can move along the direction parallel to the first rotation axis under the drive of the fixed cylinder and pierce the inactivation bag in the inactivation agent accommodating cavity;
a boss positioned between the first section and the second section is arranged on the outer surface of the fixed barrel, and the inactivation assembly further comprises a fixed nut;
the fixing nut is in threaded connection with the second section of the fixing barrel, so that the extrusion disc is fixed between the boss and the fixing nut.
2. The biological sample transport tank of claim 1, wherein there are a plurality of sample bottles, and the sample bottles are arranged in a circular array about the first axis of rotation;
the sample cutter is positioned between two adjacent sample bottles.
3. The biological sample transport tank of claim 2, wherein the sample cutter is a heating wire, the sample cutting assembly further comprising a first power source electrically connected to the heating wire;
wherein, the fusing temperature of heating wire is greater than the fusing point of sample bottle.
4. The biological sample transportation tank of claim 2, wherein the end of the sample cutter remote from the rotating portion is provided with a cutting blade;
the cutting blade is positioned between two adjacent sample bottles.
5. The biological sample transport tank of claim 1, wherein the inactivation assembly further comprises a pre-tension spring;
an abutting part extending inwards along the radial direction of the fixed cylinder is arranged at one end of the second section of the fixed cylinder, which is far away from the first section;
one end of the pre-tightening spring is abutted with the transmission part of the fixed disc, and the other end of the pre-tightening spring is abutted with the abutting part so as to be compressively fixed between the transmission part and the abutting part.
6. The biological sample transportation tank of any one of claims 1-5, further comprising:
a receiver configured to receive a manipulation instruction of the terminal device;
and the controller is in communication connection with the receiver and is configured for controlling the driving piece to output rotary torque according to the control instruction.
7. The biological sample transport tank of claim 6, further comprising a second power source;
the second power supply is in communication connection with the controller, and the second power supply is electrically connected with the driving piece.
CN202210337504.7A 2022-04-01 2022-04-01 Biological sample transport tank Active CN114655551B (en)

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* Cited by examiner, † Cited by third party
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EP0739826A1 (en) * 1995-04-28 1996-10-30 QUALIPAC Société Anonyme Closing device with an opening on the side which is axially retractable
CN107920954A (en) * 2015-06-16 2018-04-17 勃林格殷格翰维特梅迪卡有限公司 Connection and containment system
JP2016176945A (en) * 2016-04-07 2016-10-06 クレティス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングCuretis GmbH Equipment and method for lysis of sample in particular for automated and/or controlled lysis of sample
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