CN114602339B - Glue dissolving method and equipment for soft capsule preparation - Google Patents
Glue dissolving method and equipment for soft capsule preparation Download PDFInfo
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- CN114602339B CN114602339B CN202210257781.7A CN202210257781A CN114602339B CN 114602339 B CN114602339 B CN 114602339B CN 202210257781 A CN202210257781 A CN 202210257781A CN 114602339 B CN114602339 B CN 114602339B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D19/00—Degasification of liquids
- B01D19/02—Foam dispersion or prevention
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Abstract
The invention discloses a method and equipment for melting a soft capsule, which comprises the following steps: step 1: controlling the temperature in the heat-preserving barrel to be 50-55 ℃; step 2: stirring and mixing; and step 3: removing bubbles; and 4, step 4: standing for 1h; and 5: repeating the steps 2 to 4 in an idle stirring barrel; step 6: discharging the glue solution from the stirring barrel in which the glue solution preparation is finished; and 7: and repeating the steps 5 to 6. The invention can improve the preparation effect of the capsule.
Description
Technical Field
The invention belongs to the field of soft capsule preparation, and particularly relates to a method and equipment for dissolving soft capsules.
Background
The gelatin melting belongs to an important link in the preparation process of the capsule skin and also an important link in the preparation of the soft capsule, and the quality of the capsule skin is directly related to the quality of the soft capsule.
The capsule shell of the soft capsule contains three substances of edible gelatin, water and glycerol, and the proportion of the three substances can be adjusted according to requirements. In the process of gelatin melting, in order to prevent the viscosity of the gelatin from excessively decreasing, the glycerin and water are heated first, and then the gelatin is added in the process of preparing the capsule.
However, bubbles are easily generated in the process of glue melting, and the quality of the capsule is seriously influenced by the bubbles, and the bubbles are generally removed by adopting a vacuumizing mode in the prior art, but the two defects exist, namely, the effect of removing fine bubbles is not ideal, and the time is longer.
Disclosure of Invention
In view of the above technical problems, the present invention provides a method and an apparatus for melting soft capsules, which can solve the problems in the prior art.
In order to solve the technical problems, the technical scheme of the invention is as follows:
a glue dissolving method for soft capsule manufacture comprises the following steps:
step 1: adding a mixture of water and glycerol into a stirring barrel 5 in a heat-preserving barrel 1, controlling the temperature in the stirring barrel 5 to be 70-75 ℃, adding gelatin and stirring simultaneously, continuing stirring for 20-25min after the gelatin is completely added, and keeping standing for 2h;
step 2: removing bubbles, and removing the bubbles by a vacuum method;
and 3, step 3: standing for 1h;
and 4, step 4: and discharging the glue solution.
A glue dissolving method for manufacturing soft capsules comprises the following steps:
step 1: controlling the temperature in the heat-insulating barrel 1 to be 50-55 ℃;
step 2: adding a mixture of water and glycerol into a stirring barrel 5 in a heat-preserving barrel 1, controlling the temperature in the stirring barrel 5 to be 70-75 ℃, adding gelatin and stirring simultaneously, continuing stirring for 20-25min after the gelatin is completely added, and keeping standing for 2h;
and step 3: removing bubbles, and removing the bubbles by a vacuum method;
and 4, step 4: standing for 1h;
and 5: and discharging the glue solution.
The utility model provides a change gluey equipment for softgel preparation, it has the vertical bucket 3 of gluing to change gluey equipment, it includes agitator 5 and fixes bubble removing device 6 in agitator 5 top to change gluey vertical bucket 3 the top of agitator 5 is provided with feed inlet 7 and water inlet 8, the bottom of agitator 5 is provided with discharge gate 9 and drain 10.
Further, the glue melting vertical barrel 3 is provided with a heating and heat preservation device.
Furthermore, the glue melting equipment is also provided with a heat-insulating barrel 1, the heat-insulating barrel 1 is supported on the ground through a support leg 2, a plurality of glue melting vertical barrels 3 are fixed in the heat-insulating barrel 1 through fixing rings 4, and the heat-insulating barrel 1 and the glue melting vertical barrels 3 are provided with independent heating and heat-insulating devices; the discharge ports 9 at the bottoms of the glue dissolving vertical barrels 3 are connected with joint heads 11, and the sewage discharge port 10 penetrates through the heat-insulating barrel 1 and can be connected with an external sewage collecting device to discharge cleaning sewage; the joint head 11 is connected with a discharge port 12 at the bottom of the heat-preserving barrel 1, the discharge port 12 is used for discharging prepared glue solution to the outside, and valves for opening and closing are arranged at the feed inlet 7, the water inlet 8, the discharge outlet 9, the sewage discharge port 10 and the discharge port 12.
Further, the stirring barrel 5 is provided with a lower shell 13, the bubble removing device 6 is provided with an upper shell 14, the stirring barrel 5 is fixed above the stirring barrel 5 and is located in the upper shell 14, a support frame 16 is arranged in the upper shell 14, a lower motor 17 and an upper motor 18 are arranged on the support frame 16, an output shaft of the lower motor 17 is connected with a stirring shaft 19, the lower end of the stirring shaft 19 is rotatably arranged on a support ring 20 at the bottom of the lower shell 13, a stirring rod 29 is arranged on the stirring shaft 19, the stirring rod 29 is hinged in a cavity 28 on the stirring shaft 19, a balance weight 30 is arranged at the free end of the stirring rod 29, the stirring rod 29 and the balance weight 30 can be accommodated in the cavity 28, a fixed block 15 is fixed above the upper shell 14, an output shaft of the upper motor 18 is connected with a threaded rod 21, the upper end of the threaded rod 21 is rotatably supported on the fixed block 15, support blocks 22 are arranged below the fixed block 15, the support blocks 22 are sleeved on the threaded rod 21 and are provided with internal threads matched with the threaded rod 21, the support blocks 22 are connected with a plurality of connecting rods 23, the connecting holes 24 on the lower shell 13, and the sphere 25 are provided with a plurality of spherical bodies 27, and a plurality of spherical body channels 27, and a plurality of spherical body 27 is hinged with a plurality of spherical body 25, and a plurality of spherical body 27.
A glue dissolving method for soft capsule manufacture is provided, the glue dissolving device of the glue dissolving method is provided with a heat-preserving barrel 1, the heat-preserving barrel 1 is supported on the ground through a supporting leg 2, a plurality of glue dissolving vertical barrels 3 are fixed in the heat-preserving barrel 1 through a fixing ring 4, the heat-preserving barrel 1 and the glue dissolving vertical barrels 3 are respectively provided with an independent heating and heat-preserving device, the glue dissolving vertical barrels 3 comprise a stirring barrel 5 and a bubble removing device 6 fixed above the stirring barrel 5, a feed inlet 7 and a water inlet 8 are arranged above the stirring barrel 5, the bottom of the stirring barrel 5 is provided with a discharge outlet 9 and a sewage outlet 10, the discharge outlets 9 at the bottom of the glue dissolving vertical barrels 3 are connected with a joint 11, the sewage outlet 10 penetrates through the heat-preserving barrel 1, the joint 11 is connected with a discharge outlet 12 at the bottom of the heat-preserving barrel 1, the stirring barrel 5 is provided with a lower shell 13, the bubble removing device 6 is provided with an upper shell 14, a support frame 16 is arranged above the stirring barrel 5 and in the upper shell 14, a lower motor 17 and an upper motor 18 are arranged on the support frame 16, an output shaft of the lower motor 17 is connected with a stirring shaft 19, the lower end of the stirring shaft 19 is rotatably arranged on a support ring 20 at the bottom of the lower shell 13, a stirring rod 29 is arranged on the stirring shaft 19, the stirring rod 29 is hinged in a cavity 28 on the stirring shaft 19, a counterweight 30 is arranged at the free end of the stirring rod 29, the stirring rod 29 and the counterweight 30 can be accommodated in the cavity 28, a fixed block 15 is fixed above the upper shell 14, an output shaft of the upper motor 18 is connected with a threaded rod 21, the upper end of the screw rod 21 is rotatably supported on the fixed block 15, and a support block 22 is arranged below the fixed block 15, the supporting block 22 is sleeved on the threaded rod 21 and has an internal thread matched with the threaded rod 21, the supporting block 22 is connected with a plurality of connecting rods 23, the connecting rods 23 penetrate through a through hole 24 on the lower shell 13 and are hinged with a sphere 25 inside the lower shell 13, the sphere 25 is of a shell structure, a plurality of small holes 26 are uniformly distributed on the sphere 25, the sphere 25 is provided with a channel 27, and the stirring shaft 19 penetrates through the channel 27;
the glue dissolving method comprises the following steps:
step 1: controlling the temperature in the heat-preserving barrel 1 to be 50-55 ℃;
step 2: adding a mixture of water and glycerol into a stirring barrel 5 in a heat-preserving barrel 1, controlling the temperature in the stirring barrel 5 to be 70-75 ℃, adding gelatin and simultaneously stirring by driving a lower motor 17, at the moment, expanding a stirring rod 29 and a balance weight 30 under the action of centrifugal force, continuously controlling the lower motor 17 to stir for 20-25min after the gelatin is completely added, closing the lower motor 17, and keeping standing for 2h;
and step 3: removing bubbles, turning on the upper motor 18, driving the supporting block 22 to move downwards, driving the ball 25 to move downwards to enter the glue solution, taking the stirring rod 29 and the balance weight 30 into the cavity 28, enabling the ball 25 to break the bubbles, adsorbing the small bubbles into the small holes 26, then entering the ball 25, forming large bubbles in the ball 25, breaking the bubbles when the ball 25 is pulled away from the liquid level of the glue solution, and thus repeatedly removing the bubbles;
and 4, step 4: keeping the temperature in the heat-preserving barrel 1 at 50-55 ℃, and standing for 1h;
and 5: repeating the steps 2 to 4 in the idle stirring barrel 5;
step 6: discharging the glue solution from the stirring barrel 5 in which the glue solution preparation is finished;
and 7: and repeating the steps 5 to 6.
The invention has the following technical effects:
the stirring device is provided with the heat-insulating barrel, so that the temperature in the stirring barrel during stirring can be uniformly distributed, and the temperature required by the glue solution reaching the discharge opening can be maintained; the invention is provided with a plurality of long and thin columnar stirring barrels, divides the stirring device into a plurality of independent stirring barrels, can distribute and melt the glue, improves the glue melting effect and improves the capsule manufacturing quality; the third embodiment of the invention adopts the bubble removing device, which is different from the vacuum bubble removing device in the prior art, the vacuum bubble removing device in the prior art has non-ideal effect of removing fine bubbles and fine bubbles adhered to the wall, and the time is longer.
Drawings
FIG. 1 is a flow chart of a first glue melting process according to the present invention;
FIG. 2 is a flow chart of glue melting according to a second embodiment of the present invention;
FIG. 3 is a front view of a third glue melting apparatus according to an embodiment of the present invention;
FIG. 4 is a schematic view of the internal structure of the glue melting apparatus of the present invention;
FIG. 5 is an enlarged view of portion A of FIG. 4 of the present invention;
FIG. 6 is a front view of a vertical barrel for melting glue according to the present invention;
FIG. 7 is a schematic view of the internal structure of the vertical glue-dissolving barrel of the present invention;
FIG. 8 is an enlarged view of portion B of FIG. 7 in accordance with the present invention;
FIG. 9 is an enlarged view of portion C of FIG. 7 of the present invention;
FIG. 10 is an enlarged view of portion D of FIG. 7 of the present invention;
FIG. 11 is an overall cross-sectional view of a chemical conversion vertical barrel of the present invention;
FIG. 12 is an enlarged view of section E of FIG. 11 in accordance with the present invention;
FIG. 13 is an enlarged view of portion F of FIG. 11 of the present invention;
FIG. 14 is a partial schematic view of the bubble removal means of the present invention operating to the lowermost position;
FIG. 15 is a partial cross-sectional view of the present invention during rotational agitation;
in the figure, a heat-preserving container 1, supporting legs 2, a glue melting vertical container 3, a fixing ring 4, a stirring barrel 5, a bubble removing device 6, a feed inlet 7, a water inlet 8, a discharge outlet 9, a sewage discharge outlet 10, a joint 11, a discharge outlet 12, a lower shell 13, an upper shell 14, a fixing block 15, a support frame 16, a lower motor 17, an upper motor 18, a stirring shaft 19, a support ring 20, a threaded rod 21, a support block 22, a connecting rod 23, a through hole 24 (adopting a sealing ring), a sphere 25, a small hole 26, a channel 27, a cavity 28, a stirring rod 29 and a balance weight 30 are arranged.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
In the description of the present invention, it is to be understood that the terms "center", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "axial", "circumferential", and the like, indicate orientations and positional relationships based on those shown in the drawings, and are used merely for convenience of description and for simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be considered as limiting the present invention.
In the present invention, unless otherwise explicitly stated or limited, the terms "disposed," "mounted," "connected," "fixed," and the like are to be construed broadly, e.g., as being either fixedly connected or detachably connected; may be a mechanical connection; may be directly connected or indirectly connected through an intermediate. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
Furthermore, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature.
As shown in fig. 1, which is a flow chart of a glue dissolving method according to a first embodiment of the present invention, the glue dissolving method according to the first embodiment includes the following steps:
step 1: stirring and mixing, namely adding a mixture of water and glycerol into a stirring barrel 5 in a heat-insulating barrel 1, controlling the temperature in the stirring barrel 5 to be 70-75 ℃, adding gelatin and stirring simultaneously, continuing stirring for 20-25min after the gelatin is completely added, and keeping standing for 2h;
and 2, step: removing bubbles;
and 3, step 3: standing for 1h;
and 4, step 4: and discharging the glue solution.
As shown in fig. 2, a flow chart of a glue melting method in a second embodiment of the present invention is shown, and the glue melting method in the second embodiment includes the steps of:
step 1: setting the heat preservation temperature, and controlling the temperature in the heat preservation barrel 1 to be 50-55 ℃;
and 2, step: stirring and mixing, namely adding a mixture of water and glycerol into a stirring barrel 5 in a heat-insulating barrel 1, controlling the temperature in the stirring barrel 5 to be 70-75 ℃, adding gelatin and stirring simultaneously, continuing stirring for 20-25min after the gelatin is completely added, and keeping standing for 2h;
and 3, step 3: removing bubbles;
and 4, step 4: standing for 1h;
and 5: and discharging the glue solution.
As shown in fig. 3-15, a third embodiment of the present invention discloses a glue dissolving device and a glue dissolving method for soft capsule manufacture. In fig. 3, the glue melting equipment is provided with a heat-insulating barrel 1, and the heat-insulating barrel 1 is supported on the ground through a support leg 2. As shown in figure 4, a plurality of chemical glue vertical barrels 3 are fixed in the heat-preserving container 1 through a fixing ring 4, the chemical glue vertical barrels 3 are arranged along the inner side wall of the heat-preserving container 1, the heat-preserving container 1 and the chemical glue vertical barrels 3 are provided with independent heating and heat-preserving devices.
As shown in fig. 6, the glue dissolving vertical barrel 3 comprises an agitating barrel 5 and a bubble removing device 6 fixed above the agitating barrel 5, a feed inlet 7 and a water inlet 8 are arranged above the agitating barrel 5, the feed inlet 7 is used for adding materials into the agitating barrel 5, the water inlet 8 is used for adding cleaning water into the agitating barrel 5, and a discharge outlet 9 and a sewage outlet 10 are arranged at the bottom of the agitating barrel 5.
As shown in fig. 5, the discharge ports 9 at the bottom of the glue melting vertical barrels 3 are connected with joint heads 11, and the sewage discharge port 10 penetrates through the heat-preserving barrel 1 and can be connected with an external sewage collection device to discharge cleaning sewage. The joint head 11 is connected with a discharge port 12 at the bottom of the heat-preserving container 1, and the discharge port 12 is used for discharging the prepared glue solution to the outside. And valves for opening and closing are arranged at the feed inlet 7, the water inlet 8, the discharge outlet 9, the sewage discharge outlet 10 and the discharge outlet 12.
As shown in fig. 7 and 8, the mixing drum 5 has a lower casing 13, the bubble removing device 6 has an upper casing 14, a support frame 16 is fixed above the mixing drum 5 and located inside the upper casing 14, a lower motor 17 and an upper motor 18 are arranged on the support frame 16, and an output shaft of the lower motor 17 is connected with a mixing shaft 19. As shown in fig. 9, the lower end of the stirring shaft 19 is rotatably disposed on the support ring 20 at the bottom of the lower housing 13, as shown in fig. 11 and 13, a stirring rod 29 is disposed on the stirring shaft 19, the stirring rod 29 is hinged inside the cavity 28 on the stirring shaft 19, a free end of the stirring rod 29 is provided with a counterweight 30, and the stirring rod 29 and the counterweight 30 can be received inside the cavity 28.
As shown in fig. 8 and 10, a fixed block 15 is fixed above the upper housing 14, an output shaft of the upper motor 18 is connected to a threaded rod 21, an upper end of the threaded rod 21 is rotatably supported on the fixed block 15, a support block 22 is disposed below the fixed block 15, the support block 22 is sleeved on the threaded rod 21 and has an internal thread engaged with the threaded rod 21, and the support block 22 is connected to a plurality of connecting rods 23.
As shown in fig. 12, the connecting rod 23 is hinged to a ball 25 inside the lower casing 13 through a through hole 24 on the lower casing 13, the ball 25 is a casing structure, a plurality of small holes 26 are uniformly distributed on the ball 25, the diameter of the small hole 26 can be set to 1mm, 1.5mm, 2mm in one embodiment, the ball 25 has a passage 27, and the stirring shaft 19 passes through the passage 27.
The glue dissolving method using the glue dissolving equipment comprises the following steps:
step 1: setting the heat preservation temperature, and controlling the temperature in the heat preservation barrel 1 to be 50-55 ℃;
and 2, step: stirring and mixing, namely adding a mixture of water and glycerol (preservatives, opacifiers, pigments and other suitable materials to be used can be added, only main materials are listed in the application for illustration only), adding gelatin into the stirring barrel 5 at 70-75 ℃, simultaneously stirring by driving a lower motor 17, at the moment, unfolding a stirring rod 29 and a balance weight 30 under the action of centrifugal force (the state shown in figure 15 can be achieved, the unfolding is not always the same as that shown in figure 15), continuously controlling the lower motor 17 to stir for 20-25min after the gelatin is completely added, closing the lower motor 17, and keeping standing for 2h;
and 3, step 3: removing bubbles, turning on the upper motor 18, driving the supporting block 22 to move downwards, driving the ball 25 to move downwards to enter into the glue solution, and finally going to the bottom of the lower shell 13 (as shown in fig. 14) (it is to be noted that the glue solution does not completely fill the whole lower shell 13, as shown in fig. 7 (when the ball 25 is at the uppermost part, the ball 25 is not in contact with the glue solution)), the stirring rod 29 and the counterweight 30 are received into the cavity 28, the ball 25 can break the bubbles, then the small bubbles are adsorbed into the small holes 26 and then enter into the ball 25, large bubbles are formed inside the ball 25, the large bubbles are locked inside the ball shell, and the bubbles are broken when the ball 25 is pulled away from the glue solution surface, so that the bubbles are removed in a reciprocating manner (the effect of removing the small bubbles is good, particularly, the effect of the bubbles adhered to the inner wall of the lower shell is good, and the speed is high);
and 4, step 4: keeping the temperature in the heat-preserving barrel 1 at 50-55 ℃, and standing for 1h;
and 5: repeating the steps 2 to 4 in the idle stirring barrel 5;
step 6: discharging the glue solution from the stirring barrel 5 in which the glue solution preparation is finished;
and 7: and repeating the steps 5 to 6.
As shown in fig. 7, 8, 11, 12, 14 and 15, in order to allow the ball 25 to move smoothly in the glue shaft 3, the diameter of the ball 25 is slightly smaller than the inner diameter of the glue shaft 3.
It should be noted that the proportion of each component of the capsule skin is configured according to production needs, the proportion is not protected in the invention, but only a method and corresponding equipment are protected, and the invention adopts a conventional control mode in the field of soft capsule manufacturing, and the details are not described.
The invention is provided with the heat-preserving barrel, so that the temperature of the stirring barrel during stirring can be uniformly distributed, and the temperature required by the glue solution reaching the discharge opening can be maintained; the invention is provided with a plurality of long and thin columnar stirring barrels, divides the stirring device into a plurality of independent stirring barrels, can distribute and melt the glue, improves the glue melting effect and improves the capsule manufacturing quality; the third embodiment of the invention adopts the bubble removing device, which is different from the vacuum bubble removing device in the prior art, the vacuum bubble removing device in the prior art has non-ideal effect of removing fine bubbles and fine bubbles adhered to the wall, and the time is longer.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.
Claims (4)
1. A glue dissolving equipment for soft capsule preparation is characterized in that: the glue melting equipment is provided with a glue melting vertical barrel (3), the glue melting vertical barrel (3) comprises a stirring barrel (5) and a bubble removing device (6) fixed above the stirring barrel (5), a feeding hole (7) and a water inlet (8) are arranged above the stirring barrel (5), and a discharging hole (9) and a sewage draining outlet (10) are arranged at the bottom of the stirring barrel (5);
the stirring barrel (5) is provided with a lower shell (13), the bubble removing device (6) is provided with an upper shell (14), the bubble removing device is fixed above the stirring barrel (5) and is positioned in the upper shell (14) and is provided with a support frame (16), a lower motor (17) and an upper motor (18) are arranged on the support frame (16), an output shaft of the lower motor (17) is connected with a stirring shaft (19), the lower end of the stirring shaft (19) is rotatably arranged on a support ring (20) at the bottom of the lower shell (13), a stirring rod (29) is arranged on the stirring shaft (19), the stirring rod (29) is hinged in a cavity (28) on the stirring shaft (19), the free end of the stirring rod (29) is provided with a balance weight (30), the stirring rod (29) and the balance weight (30) can be accommodated in the cavity (28), a fixed block (15) is fixed above the upper shell (14), an output shaft of the upper motor (18) is connected with a fixed block (21), the upper end of the fixed block (21) is rotatably supported on the threaded rod (15), the threaded rod (15) is arranged on the lower end of the threaded rod (15), the threaded rod (22), and the support block (21) is provided with an internal thread matching block (22), supporting shoe (22) are connected with a plurality of connecting rods (23), through-hole (24) and the inside spheroid (25) of casing (13) are articulated down passed through casing (13) connecting rod (23), spheroid (25) are shell structure, the equipartition has a plurality of apertures (26) on spheroid (25), spheroid (25) have passageway (27), (mixing) shaft (19) pass passageway (27).
2. The glue dissolving device for soft capsule manufacturing according to claim 1, characterized in that: the glue melting vertical barrel (3) is provided with a heating and heat preservation device.
3. The glue dissolving device for soft capsule manufacturing according to claim 2, characterized in that: the glue melting equipment is also provided with a heat-insulating barrel (1), the heat-insulating barrel (1) is supported on the ground through a support leg (2), a plurality of glue melting vertical barrels (3) are fixed in the heat-insulating barrel (1) through fixing rings (4), and the heat-insulating barrel (1) and the glue melting vertical barrels (3) are provided with independent heating and heat-insulating devices; the discharge ports (9) at the bottoms of the glue dissolving vertical barrels (3) are connected with joint heads (11), and the sewage discharge port (10) penetrates through the heat-insulating barrel (1) and can be connected with an external sewage collecting device to discharge cleaning sewage; the joint head (11) is connected with a discharge opening (12) at the bottom of the heat-insulating barrel (1), the discharge opening (12) is used for discharging prepared glue liquid to the outside, and valves for opening and closing are arranged at the feed inlet (7), the water inlet (8), the discharge outlet (9), the drain outlet (10) and the discharge opening (12).
4. The glue melting method of the glue melting equipment for soft capsule manufacturing according to claim 3, characterized by comprising the following steps:
the glue dissolving method comprises the following steps:
step 1: controlling the temperature in the heat-insulating barrel (1) to be 50-55 ℃;
and 2, step: adding a mixture of water and glycerol into a stirring barrel (5) in a heat-preserving barrel (1), controlling the temperature in the stirring barrel (5) to be 70-75 ℃, adding gelatin, simultaneously stirring by driving a lower motor (17), unfolding a stirring rod (29) and a balance weight (30) under the action of centrifugal force, continuously controlling the lower motor (17) to stir for 20-25min after the gelatin is completely added, closing the lower motor (17), and keeping standing for 2h;
and 3, step 3: removing bubbles, turning on an upper motor (18), driving a supporting block (22) to move downwards, driving a ball body (25) to move downwards to enter glue solution, taking a stirring rod (29) and a balance weight (30) into a cavity (28), enabling the ball body (25) to break the bubbles, adsorbing small bubbles into small holes (26), then entering the inside of the ball body (25), forming large bubbles in the ball body (25), breaking the bubbles when the ball body (25) is pulled away from the liquid level of the glue solution, and thus repeatedly removing the bubbles;
and 4, step 4: keeping the temperature in the heat-preserving barrel (1) at 50-55 ℃, and standing for 1h;
and 5: repeating the steps 2 to 4 in the idle stirring barrel (5);
step 6: discharging the glue solution from the stirring barrel (5) which finishes the preparation of the glue solution;
and 7: and repeating the steps 5 to 6.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210257781.7A CN114602339B (en) | 2022-03-16 | 2022-03-16 | Glue dissolving method and equipment for soft capsule preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210257781.7A CN114602339B (en) | 2022-03-16 | 2022-03-16 | Glue dissolving method and equipment for soft capsule preparation |
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| Publication Number | Publication Date |
|---|---|
| CN114602339A CN114602339A (en) | 2022-06-10 |
| CN114602339B true CN114602339B (en) | 2023-01-24 |
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| CN202210257781.7A Active CN114602339B (en) | 2022-03-16 | 2022-03-16 | Glue dissolving method and equipment for soft capsule preparation |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP5326117B2 (en) * | 2008-08-25 | 2013-10-30 | 株式会社ＡＭＢｉＳ | Antifoaming device, culture system and container with antifoaming device |
| CN106619563A (en) * | 2016-12-23 | 2017-05-10 | 北京康远制药有限公司 | Preparation method of Yiganling soft capsule |
| CN207237727U (en) * | 2017-08-02 | 2018-04-17 | 南宁富莱欣生物科技有限公司 | A kind of change glue tank with ultrasound source |
| JP2020114285A (en) * | 2019-01-17 | 2020-07-30 | 三井化学株式会社 | Preparation device |
| CN211025239U (en) * | 2019-10-03 | 2020-07-17 | 宜昌百吉生物科技有限公司 | Device for eliminating foam of glucomannan solution |
| CN211274459U (en) * | 2019-11-04 | 2020-08-18 | 河南怀雪生物科技有限公司 | Agitating unit is used in skin care products production |
| CN212914670U (en) * | 2020-05-24 | 2021-04-09 | 青海省畜牧兽医科学院 | Yak is bred and herd family and uses yak milk filter equipment with clear away bubble function |
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2022
- 2022-03-16 CN CN202210257781.7A patent/CN114602339B/en active Active
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