CN114590018A - Ultrasonic blood pressure patch manufacturing method based on silk-screen printing - Google Patents
Ultrasonic blood pressure patch manufacturing method based on silk-screen printing Download PDFInfo
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- CN114590018A CN114590018A CN202210243727.7A CN202210243727A CN114590018A CN 114590018 A CN114590018 A CN 114590018A CN 202210243727 A CN202210243727 A CN 202210243727A CN 114590018 A CN114590018 A CN 114590018A
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- 238000007650 screen-printing Methods 0.000 title claims abstract description 48
- 230000036772 blood pressure Effects 0.000 title claims abstract description 29
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- 229920005839 ecoflex® Polymers 0.000 claims abstract description 7
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- 238000004806 packaging method and process Methods 0.000 claims abstract description 5
- 238000011049 filling Methods 0.000 claims abstract description 4
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 26
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- CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 claims description 4
- 238000004987 plasma desorption mass spectroscopy Methods 0.000 claims description 4
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- 238000003756 stirring Methods 0.000 claims description 4
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Images
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41F—PRINTING MACHINES OR PRESSES
- B41F15/00—Screen printers
- B41F15/08—Machines
- B41F15/0804—Machines for printing sheets
- B41F15/0813—Machines for printing sheets with flat screens
- B41F15/0818—Machines for printing sheets with flat screens with a stationary screen and a moving squeegee
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41F—PRINTING MACHINES OR PRESSES
- B41F15/00—Screen printers
- B41F15/14—Details
- B41F15/34—Screens, Frames; Holders therefor
- B41F15/36—Screens, Frames; Holders therefor flat
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41M—PRINTING, DUPLICATING, MARKING, OR COPYING PROCESSES; COLOUR PRINTING
- B41M1/00—Inking and printing with a printer's forme
- B41M1/12—Stencil printing; Silk-screen printing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41M—PRINTING, DUPLICATING, MARKING, OR COPYING PROCESSES; COLOUR PRINTING
- B41M1/00—Inking and printing with a printer's forme
- B41M1/26—Printing on other surfaces than ordinary paper
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41P—INDEXING SCHEME RELATING TO PRINTING, LINING MACHINES, TYPEWRITERS, AND TO STAMPS
- B41P2217/00—Printing machines of special types or for particular purposes
- B41P2217/50—Printing presses for particular purposes
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Abstract
The invention discloses a silk-screen printing-based ultrasonic blood pressure patch manufacturing method, which comprises the following steps: manufacturing a microcircuit by utilizing screen printing; piezoelectric transducer and wire bonding; filling the two glass slides by using silicone and Ecoflex, and curing at room temperature to realize elastic packaging; and taking out the glass slide to obtain the ultrasonic blood pressure patch. The method for preparing the microcircuit of the ultrasonic blood pressure patch by using the screen printing technology is simple, has low requirements on equipment, greatly reduces the process difficulty and economic cost, and simplifies the process flow.
Description
Technical Field
The invention belongs to the technical field of human blood pressure measuring devices, and particularly relates to a manufacturing method of an ultrasonic blood pressure patch based on screen printing.
Background
Blood pressure monitoring is widely used clinically as a reliable diagnostic method. The traditional measurement principle can be mainly divided into an auscultation method and an oscillography method, and the precision and the use threshold of the auscultation method and the oscillography method are just opposite.
In recent years, as a kind of biological device, an ultrasonic blood pressure patch based on a piezoelectric material is in the spotlight. The blood pressure patch has the advantages of flexibility, portability, high precision, wearability, continuous monitoring and the like. The manufacturing process of such devices is relatively complex and requires high demands on equipment and operators. The most important link is the manufacturing of the microcircuit, the existing process is developed around laser ablation or photoetching, the process difficulty is high, the economic cost is high, and the method is an important reason for hindering the large-scale application of the device.
In summary, there is a need for an improved method of manufacturing an ultrasound blood pressure patch.
Disclosure of Invention
In order to solve the problems of the existing ultrasonic blood pressure patch manufacturing process, the invention mainly aims to provide an ultrasonic blood pressure patch manufacturing method based on a screen printing technology.
Therefore, the method for manufacturing the ultrasonic blood pressure patch based on the screen printing comprises the following steps:
s1 manufacturing microcircuit by screen printing
S11: drawing a microcircuit plan, and manufacturing a screen printing template; wherein the microcircuit plan view includes a bottom microcircuit and a top microcircuit;
the bottom micro circuit consists of bottom conductive silver paste circuits which are arranged in a criss-cross mode, and a bottom circular electrode is arranged at each intersection of the conductive silver paste circuits;
the top microcircuit comprises a plurality of top connecting circuits with the same number as the bottom circular electrodes, and each top connecting circuit comprises a top conductive silver paste circuit, and a lead contact pad and a top circular electrode which are respectively connected with the connecting ends of the top conductive silver paste circuit;
the bottom conductive silver paste circuit and the top conductive silver paste circuit are both bent and extended in a snake shape;
s12: mounting the manufactured screen printing template and the scraper on a screen printing device;
s13: coating a proper amount of conductive silver paste in front of an upper scraper of an installed screen printing template, and placing a glass slide lined with a flexible polymer film below the screen printing template in advance;
s14: making the scraper pass through a pattern area on the screen printing template to form a microcircuit on the flexible polymer film;
s2, piezoelectric transducer and wire bonding
S21: cutting a piezoelectric transducer into square small blocks with proper sizes in advance, and placing the piezoelectric transducers above a top circular electrode of a manufactured top microcircuit one by one;
s22: thermally bonding the piezoelectric transducer and the top microcircuit;
s23: placing a lead on a lead contact pad of the bottom microcircuit, and bonding by utilizing hot pressing;
s24: aligning each bottom circular electrode on the bottom microcircuit with each piezoelectric transducer one by one, and then carrying out thermal bonding;
s3, filling the two glass slides by using silicone and Ecoflex, and curing at room temperature to realize elastic packaging;
and S4, taking out the glass slide to obtain the ultrasonic blood pressure patch.
Specifically, the conductive silver paste is gently stirred by a plastic oil stirring knife before use.
Specifically, the bonding temperature between the circular electrode and the piezoelectric transducer and the bonding temperature between the lead and the lead contact pad are both 150 ℃ and the bonding time is 5 minutes.
Specifically, the screen printing squeegee angle was 75 °.
Specifically, the method comprises the following steps: the thickness of the flexible polymer film is 15 μm when PDMS is adopted.
Specifically, the diameter of the circular electrode is 160 μm, and the line width is 60 μm.
Specifically, the screen printing template is 200 meshes.
Compared with the prior art, at least one embodiment of the invention has the following beneficial effects:
(a) the core component-microcircuit of the ultrasonic blood pressure patch is prepared by adopting the screen printing technology, so that the method is simple, the requirement on equipment is not high, the process difficulty and the economic cost are greatly reduced, the process flow is simplified, and the device is favorably promoted to be applied in a large scale.
(b) The screen printing plate is soft and has certain elasticity, can be used for printing on flexible articles such as polymer films and the like, and is not limited by the surface shape and the area size of a printing stock. The flexibility of the device itself is not affected by the preparation of the device by screen printing.
(c) By adjusting and optimizing the structure and materials of the device, the acoustic performance of the device is not obviously influenced by the process change.
(d) The traditional screen printing process is rough, is mainly used for printing characters and patterns, is a little used for manufacturing a printed circuit board, can be applied to the preparation of the ultrasonic sphygmomanometer by adjusting the process and groping parameters, and expands the application dimension of the screen printing.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.
FIG. 1 is a schematic diagram of a bottom microcircuit structure provided by an embodiment of the present invention;
FIG. 2 is a schematic diagram of a top microcircuit structure provided by an embodiment of the present invention;
FIG. 3 is a schematic structural diagram of an ultrasound blood pressure patch provided by an embodiment of the present invention;
FIG. 4 is a schematic view of a layered ultrasound blood pressure patch provided by an embodiment of the present invention;
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the invention and to simplify the description, and are not intended to indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and are therefore not to be considered limiting of the invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
A manufacturing method of an ultrasonic blood pressure patch based on screen printing comprises the following steps:
s1, manufacturing microcircuit by screen printing
S11: drawing a microcircuit plan, and manufacturing a screen printing template; wherein the content of the first and second substances,
referring to fig. 1 and 2, drawing a plan view of a microcircuit, and making a screen printing stencil; the micro circuit plane diagram comprises a bottom micro circuit and a top micro circuit, the bottom micro circuit is composed of bottom conductive silver paste circuits which are arranged in a criss-cross mode, a bottom round electrode is arranged at each intersection of the conductive silver paste circuits, the top micro circuit comprises a plurality of top connecting circuits which are consistent with the bottom round electrodes in number, and each top connecting circuit comprises a top conductive silver paste circuit, and a lead contact pad and a top round electrode which are respectively connected to the connecting ends of the top conductive silver paste circuits; the bottom conductive silver paste circuit and the top conductive silver paste circuit are both in a snake shape which is bent and extended left and right towards a specific direction;
s12: and (4) mounting the manufactured screen printing template and the scraper on a screen printing device.
The inventor further researches and finds that the mesh number of the screen printing template is controlled to be 200 meshes, which is suitable because if the mesh number of the screen is too high, the aperture is too small, so that the transmittance of the silver paste is greatly reduced during printing, and the screen cannot be too thick, otherwise, microcracks are easily generated when the conductive silver paste pattern is separated from the screen, and the conductivity of the circuit is possibly reduced, and even the circuit is broken and fails;
s13: after gently stirring the conductive silver paste by using a plastic oil stirring knife, coating a proper amount of conductive silver paste in front of a scraper on the installed screen printing template, and placing a glass slide lined with a flexible polymer film below the screen printing template in advance;
s14: the scraper is used for scratching a pattern area on the screen printing template to form a microcircuit on the flexible polymer film, the angle of the screen printing scraper is 75 degrees, and when the flexible polymer film adopts PDMS, the thickness can be about 15 microns so as to balance mechanical robustness and acoustic emission performance;
s2, piezoelectric transducer and wire bonding
S21: cutting piezoelectric transducers (PZT) into square small blocks with proper sizes in advance, and placing the PZT one by one above a top circular electrode of a manufactured top microcircuit;
s22: thermally bonding the piezoelectric transducer and the top microcircuit, as shown in FIG. 2;
s23: placing the lead on the lead contact pad of the bottom microcircuit, and bonding by using hot pressing, as shown in fig. 2;
s24: after aligning each bottom circular electrode on the bottom microcircuit with each piezoelectric transducer one by one, carrying out thermal bonding, as shown in fig. 2;
wherein the diameter of the circular electrode is 160 μm, the line width is 60 μm, the bonding temperature between the circular electrode and the piezoelectric transducer and between the lead and the lead contact pad is 150 ℃, and the duration is 5 minutes.
S3, filling the two glass slides by using silicone and Ecoflex, and curing at room temperature to realize elastic packaging;
the reason for choosing silicone and Ecoflex is that the inventors also evaluated the choice of flexible substrate and encapsulant materials. Flexible substrates such as polyvinyl alcohol (PVA), Polyester (PET), Polyimide (PI), polyethylene naphthalate (PEN), and the like have uneven flexibility, insulation, flexibility, and strength. In the design of the sealing layer, the sealing layer is required to be capable of enduring long-term bending deformation according to the characteristics of a flexible electronic system, so that the material of the sealing layer is the same as that of the substrate, and the fatigue resistance needs to meet certain requirements. Common sealant materials include acrylics, epoxies, and polyimides, among others. These substrate and package materials are widely used in various flexible sensors and biosensors. From the starting point of better process compatibility and biocompatibility, PDMS is adopted as a substrate material of a device, and Ecoflex is used for packaging. Meanwhile, from the acoustic coupling of each layer of the device, an additional layer of silicone is required to be added besides the Ecoflex so as to ensure that the device can work normally.
And S4, taking out the glass slide to obtain the ultrasonic blood pressure patch, wherein the two layers of flexible polymer films respectively form a matching layer and a substrate of the ultrasonic blood pressure patch as shown in figures 3 and 4.
From the performance of the device, the stability of the structure and the tolerance to processing, it is necessary to improve the scalability of the flexible device in the layout, the ductility of the device can be greatly improved by designing the elastic interconnection in the non-coplanar buckling form on the flexible substrate with prestress or directly designing the coplanar two-dimensional elastic interconnection on the flexible substrate. A bridge is a thin metal wire in a serpentine shape. The curvature parameters of the snake-shaped corrugated wire are obtained through a plurality of experiments, the elastic film and the snake-shaped circuit are combined, the flexibility of the device is realized by applying a silk-screen printing process, the device can adapt to the skin, and the device can be stretched, bent and twisted within a certain range without affecting the performance of the device.
The embodiment of the invention has the following advantages and positive effects: (a) the screen printing method is simple, has low requirements on equipment, greatly reduces the process difficulty and economic cost, simplifies the process flow and is beneficial to promoting the large-scale application of devices; (b) the screen printing plate is soft and has certain elasticity. The printing ink is suitable for printing on hard articles and also suitable for printing on flexible articles such as polymer films and the like; (c) the silk-screen printing is not limited by the surface shape and the area size of a printed object, and although a hard glass plate is arranged under the flexible substrate before printing, the printing quality is not influenced by removing the hard glass plate; (d) the pressure applied by screen printing is small, and the flexible substrate is not easy to be damaged.
Any embodiment disclosed herein above is meant to disclose, unless otherwise indicated, all numerical ranges disclosed as being preferred, and any person skilled in the art would understand that: the preferred ranges are merely those values which are obvious or representative of the technical effect which can be achieved. Since the numerical values are too numerous to be exhaustive, some of the numerical values are disclosed in the present invention to illustrate the technical solutions of the present invention, and the above-mentioned numerical values should not be construed as limiting the scope of the present invention.
Meanwhile, if the invention as described above discloses or relates to parts or structural members fixedly connected to each other, the fixedly connected parts can be understood as follows, unless otherwise stated: a detachable fixed connection (for example using bolts or screws) is also understood as: non-detachable fixed connections (e.g. riveting, welding), but of course, fixed connections to each other may also be replaced by one-piece structures (e.g. manufactured integrally using a casting process) (unless it is obviously impossible to use an integral forming process).
In addition, terms used in any technical aspect of the present disclosure for indicating positional relationship or shape include, unless otherwise stated, states or shapes similar, analogous or approximate thereto. Any part provided by the invention can be assembled by a plurality of independent components or can be manufactured by an integral forming process.
The above examples are merely illustrative for clearly explaining the present invention and do not limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. Nor is it necessary or exhaustive for all embodiments. And obvious variations or modifications of the invention may be made without departing from the scope of the invention.
Claims (7)
1. A manufacturing method of an ultrasonic blood pressure patch based on screen printing is characterized by comprising the following steps:
s1 manufacturing microcircuit by screen printing
S11: drawing a plan view of the microcircuit, and manufacturing a screen printing template; wherein the microcircuit plan view includes a bottom microcircuit and a top microcircuit;
the bottom micro circuit consists of bottom conductive silver paste circuits which are arranged in a criss-cross mode, and a bottom circular electrode is arranged at each intersection of the conductive silver paste circuits;
the top microcircuit comprises a plurality of top connecting circuits with the same number as the bottom circular electrodes, and each top connecting circuit comprises a top conductive silver paste circuit, and a lead contact pad and a top circular electrode which are respectively connected with the connecting ends of the top conductive silver paste circuit;
the bottom conductive silver paste circuit and the top conductive silver paste circuit are both bent and extended in a snake shape;
s12: mounting the manufactured screen printing template and the scraper on a screen printing device;
s13: coating a proper amount of conductive silver paste on the installed screen printing template in front of a scraper, and placing a glass slide lined with a flexible polymer film below the screen printing template in advance;
s14: making the scraper pass through a pattern area on the screen printing template to form a microcircuit on the flexible polymer film;
s2, piezoelectric transducer and wire bonding
S21: cutting a piezoelectric transducer into square small blocks with proper sizes in advance, and placing the piezoelectric transducers above a top circular electrode of a manufactured top microcircuit one by one;
s22: thermally bonding the piezoelectric transducer and the top microcircuit;
s23: placing a lead on a lead contact pad of the bottom microcircuit, and bonding by utilizing hot pressing;
s24: aligning each bottom circular electrode on the bottom microcircuit with each piezoelectric transducer one by one, and then carrying out thermal bonding;
s3, filling the two glass slides by using silicone and Ecoflex, and curing at room temperature to realize elastic packaging;
and S4, taking out the glass slide to obtain the ultrasonic blood pressure patch.
2. The method of manufacturing an ultrasonic blood pressure patch according to claim 1, wherein: the bonding temperature between the circular electrode and the piezoelectric transducer and between the lead and the lead contact pad is 150 ℃, and the bonding time is 5 minutes.
3. The method of manufacturing an ultrasonic blood pressure patch according to claim 1, wherein: the conductive silver paste is gently stirred by a plastic oil stirring knife before use.
4. The method of manufacturing an ultrasonic blood pressure patch according to claim 1, wherein: the screen printing squeegee angle was 75 °.
5. The method of manufacturing an ultrasonic blood pressure patch according to claim 1, wherein: the thickness of the flexible polymer film is 15 μm when PDMS is adopted.
6. The method of manufacturing an ultrasonic blood pressure patch according to claim 1, wherein: the diameter of the circular electrode is 160 μm, and the line width is 60 μm.
7. The method of manufacturing an ultrasonic blood pressure patch according to claim 1, wherein: the screen printing template is 200 meshes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210243727.7A CN114590018A (en) | 2022-03-10 | 2022-03-10 | Ultrasonic blood pressure patch manufacturing method based on silk-screen printing |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202210243727.7A CN114590018A (en) | 2022-03-10 | 2022-03-10 | Ultrasonic blood pressure patch manufacturing method based on silk-screen printing |
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| CN114590018A true CN114590018A (en) | 2022-06-07 |
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| CN202210243727.7A Pending CN114590018A (en) | 2022-03-10 | 2022-03-10 | Ultrasonic blood pressure patch manufacturing method based on silk-screen printing |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115844447A (en) * | 2022-11-13 | 2023-03-28 | 复旦大学 | Flexible polymer ultrasonic probe |
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Application publication date: 20220607 |