CN114569235B - Hepatic carcinoma portal vein cancer suppository capturing device - Google Patents

Hepatic carcinoma portal vein cancer suppository capturing device Download PDF

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Publication number
CN114569235B
CN114569235B CN202210241950.8A CN202210241950A CN114569235B CN 114569235 B CN114569235 B CN 114569235B CN 202210241950 A CN202210241950 A CN 202210241950A CN 114569235 B CN114569235 B CN 114569235B
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cancer
guide wire
plug
inner tube
baffle
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CN114569235A (en
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王泓天
包蓉
梁永刚
吴卓轩
曹姝
陈彧洋
陈晓菊
陈凡
吴昕昱
廖明恒
刘畅
金谌
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Sichuan University
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Sichuan University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22079Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with suction of debris
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1405Electrodes having a specific shape
    • A61B2018/1425Needle

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Otolaryngology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • External Artificial Organs (AREA)

Abstract

The invention discloses a hepatic portal vein cancer embolus capturing device which comprises a guide wire, an umbrella cover, a suction tube, a distal baffle, a suction tube orifice, an inner tube, a handle and other components. The guide wire shuttles into the inner tube, can reach the cancer plug part under the action of the handle, and can realize the puncture of the cancer plug. The front end of the umbrella cover is fixed on the guide wire, when the guide wire is pulled backwards, the micro baffle plate with larger diameter is clamped at the opening of the inner tube, and the elastic support inside the umbrella cover is opened together with the umbrella cover to cover the cancer plug inside the umbrella cover, so that the cancer plug is captured. The inner tube is nested in the suction tube with a clearance to draw the captured portal vein cancer plug out of the body. The far-end baffle is fixed outside the suction tube, so that the cancer plug can be blocked, and cancer cells are prevented from escaping. The invention can realize the capture of the portal vein cancer suppository under the condition of avoiding the vascular injury to the maximum extent, and has the advantages of safety, accuracy and simple operation.

Description

Hepatic carcinoma portal vein cancer suppository capturing device
Technical Field
The invention relates to the technical field of medical equipment, in particular to a hepatic carcinoma portal vein cancer suppository capturing device.
Background
Portal vein cancer embolism mainly originates from primary liver cancer, can cause portal hypertension, refractory ascites and the like, and is closely related to recurrence and metastasis after liver cancer operation.
The current clinical method for the intravenal treatment of portal cancer suppositories generally refers to portal stent combination 125 I particle implantation, portal vein intracavity radio frequency ablation treatment and the like.
However, the cancer plug which is involved in the secondary branch distal to the portal vein cannot be implanted by a stent, and the radiofrequency ablation can cause local tissue of the liver to release various cytokines, and the biological cytokines can promote the recurrence and metastasis of the tumor and the cancer plug, so that the method has a certain limitation in the treatment of the portal vein cancer plug. Therefore, the device for capturing the portal vein cancer plug in the portal vein cavity can avoid tissue damage and cancer plug recurrence risk caused by radio frequency ablation, can solve the problem that the stent cannot be implanted under some conditions, and provides a new thought for the portal vein cavity treatment of the portal vein cancer plug.
Disclosure of Invention
The invention aims to provide a liver cancer portal vein cancer suppository capturing device which can capture portal vein cancer suppositories under the condition of avoiding vascular injury, dredge blood vessels, relieve liver cancer complications such as portal vein hypertension and the like caused by the portal vein cancer suppositories, and has the advantages of safety, accuracy and simplicity in operation.
The aim of the invention is achieved by the following technical scheme:
the invention provides a hepatic portal vein cancer embolus capturing device which comprises an umbrella cover (1), a suction tube (2), a far-end baffle plate (3), a suction tube orifice (5), an inner tube (4), a handle (6), a guide wire (7) and other parts. The inner tube (4) is connected with the handle (6) through a groove, a guide wire (7) penetrates through the hollow columnar structure of the inner tube, and the guide wire (7) can move back and forth in the inner tube (4);
further, the handle (6) is composed of a bottom plate (61), a hydraulic rod (62), a cover plate (63), a latch (64), a shaft (65) and a supporting frame (66). The front end of the cover plate (63) is connected with the supporting frame (66) through the shaft (65), the rear end of the cover plate (63) is connected with the hydraulic rod (62) through the shaft (65), and the supporting frame (66) and the bottom end of the hydraulic rod (62) are fixed on the bottom plate (61). The latch (64) is fixed at the lower end of the cover plate (63), and in the process of pressing the hydraulic rod (62), the latch (64) forwards pushes the guide wire (7) through the extrusion action, and the guide wire (7) is delivered to the cancer plug part, so that the accuracy of capturing the cancer plug is realized. A semicircular groove is formed in the middle of the bottom plate (61), the front half part of the groove is used for fixing the inner tube (4), and the rear half part of the groove is used for pushing the guide wire (7);
furthermore, a conical electrotome (741) and a miniature conductive wire (742) are arranged on a wire guide head (74) at the front end of the guide wire (7), and the conical electrotome (741) can realize the puncture of the cancer plug under the action of current. The rear end of the yarn guiding head (74) is provided with an umbrella cover (1), and an elastic bracket (71) is arranged inside the umbrella cover (1). The front end of the elastic support (71) is fixed on the guide wire (7), a miniature spring (72) is arranged in the elastic support to maintain the closing state of the umbrella cover (1) and the elastic support (71) in the forward pushing process, and the annular miniature baffle (73) at the rear end can slide on the guide wire. When the guide wire (7) is pulled backwards, the micro baffle plate (73) with larger diameter is clamped at the opening of the inner tube (4), the elastic support (71) is opened together with the umbrella cover (1) to cover the cancer plug therein, so that the cancer plug is captured;
furthermore, the far-end baffle (3) is fixed outside the suction tube (2) to block cancer plugs and prevent cancer cells from escaping, and the spiral circular appearance of the far-end baffle (3) can reduce the pressure of the far-end baffle on the wall of a blood vessel and avoid damaging the blood vessel; the baffle is provided with holes with different sizes, so that blood can pass through conveniently, and meanwhile, the holes can be subjected to leak detection and deficiency repair due to the spiral appearance of the baffle, so that the effectiveness of blocking cancer cells is improved; the outer ring is in an intermittent arc shape, so that the resistance of the device in the movement of the blood vessel cavity can be reduced;
further, the inner tube (4) is nested in the suction tube (2) with a certain gap left so as to suck the captured portal vein cancer plug out of the body.
The technical scheme of the invention has at least one of the following beneficial effects:
1. the invention realizes the accuracy of capturing the portal vein cancer suppository, reduces the occurrence risk of liver cancer complications caused by the cancer suppository, and provides a new scheme for the endovascular treatment of the hepatic carcinoma portal vein cancer suppository.
2. The invention realizes the removal of cancer plugs under the minimally invasive condition, and can effectively avoid the risk of infection after the operation of the same type of large wounds.
3. The invention realizes the minimization of vascular injury, the far-end baffle of the device adopts a spiral shape, the pressure of the far-end baffle on the inner wall of the blood vessel can be reduced, the outermost ring of the far-end baffle is in an intermittent circular shape, and the friction force with the inner wall of the blood vessel can be reduced.
Drawings
The drawings are only for purposes of illustrating particular embodiments and are not to be construed as limiting the invention, like reference numerals being used to refer to like parts throughout the several views.
FIG. 1 is an external view of the present invention;
FIG. 2 is a schematic view of the canopy of the present invention;
FIG. 3 is a schematic view of a handle of the present invention;
fig. 4 is a schematic view of a guidewire of the present invention.
Reference numerals
1-an umbrella cover; 2-suction tube; 3-a distal baffle; 4-an inner tube; 5-suction nozzle; 6, a handle; 7-a guide wire; part of the handle (61-bottom plate, 62-hydraulic rod, 63-cover plate, 64-latch, 65-shaft, 66-support frame); portions of the guide wire (71-elastic support, 72-micro spring, 73-micro baffle, 74-guide wire, 741-tapered electric knife, 742-micro conductive wire).
Detailed Description
The following detailed description of preferred embodiments of the invention is made in connection with the accompanying drawings, which form a part hereof, and together with the description of the embodiments of the invention, are used to explain the principles of the invention, and are not intended to limit the scope of the invention. In describing embodiments of the present invention, it should be noted that, unless explicitly stated and limited otherwise, the term "coupled" should be interpreted broadly, for example, as a fixed connection, a removable connection, or an integral connection, as a mechanical connection, as an electrical connection, as a direct connection, or as an indirect connection via an intermediary. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art according to the specific circumstances. The terms "front", "rear", and "within … …" are used throughout the description to refer to the relative positions of the components of the device, such as the relative positions of the canopy 1 and the resilient support 71 inside and outside the device. It will be appreciated that the devices are versatile, irrespective of their orientation in space.
The invention is described in further detail below with reference to the accompanying drawings.
As shown in the figure, the cancer embolus removing device comprises an umbrella cover (1), a suction tube (2), a distal baffle (3), an inner tube (4), a suction tube orifice (5), a handle (6) and a guide wire (7). Wherein, integrated into one piece or processing have the holding chamber on suction tube (2), and the both ends and the outside intercommunication of suction tube (2), the front end of suction tube (2) is towards the vascular distal end, and the other end is the rear end, links to each other with suction pipe mouth (5), connects suction device afterwards. The suction tube (2) can be arranged in the portal vein, specifically, the diameter of the suction tube (2) is smaller than the inner diameter of a tube (such as a blood vessel) with a cancer plug of a tumor patient, specifically, the diameter can be set to be 8mm-20mm according to the requirement, the suction tube (2) has certain strength and cannot deform, the suction tube (2) can be made of plastic with certain strength and difficult to deform according to the requirement, for example, TPE (Thermoplastic Elastomer) material can be adopted; the inner tube (4) is movably sleeved in the accommodating cavity of the suction tube (2) and can extend out of the suction tube (2) from the front end and/or the rear end of the suction tube (2), and the length of the inner tube (4) is longer than that of the suction tube (2); the inner tube (4) is integrally formed or processed with a containing cavity which can be used for containing a guide wire (7), the outer diameter of the inner tube (4) is smaller than the inner diameter of the suction tube (2), and a certain gap is reserved, so that the captured portal vein cancer plug can be sucked out of the body; the guide wire (7) is movably sleeved in the second accommodating cavity of the inner tube (4), and can extend out of the inner tube (4) from the front end and/or the rear end of the inner tube (4), and the length of the guide wire (7) is larger than that of the inner tube (4).
Further, the movement of the guide wire (7) is controlled by a handle (6), and the handle (6) is composed of a bottom plate (61), a hydraulic rod (62), a cover plate (63), a latch (64), a shaft (65) and a supporting frame (66). A semicircular groove is formed in the middle of the bottom plate (61), the front half part of the groove is used for fixing the inner tube (4), and the rear half part of the groove is used for pushing the guide wire (7); the front end of the cover plate (63) is connected with the shaft (65) and the supporting frame (66), the rear end of the cover plate (63) is connected with the hydraulic rod (62) through the shaft (65), and the bottom ends of the supporting frame (66) and the hydraulic rod (62) are fixed on the bottom plate (61). The latch (64) is fixed at the lower end of the cover plate (63), and in the process of pressing the hydraulic rod (62), the latch (64) forwards pushes the guide wire (7) through the extrusion action, and the guide wire (7) is delivered to the cancer plug part, so that the accuracy of capturing the cancer plug is realized.
Furthermore, a conical electric knife (741) and a miniature conductive wire (742) are arranged on a wire guide head (74) at the front end of the guide wire (7), and the conical electric knife (741) can generate electric sparks under the tip discharge effect so as to realize the cauterization and puncture of cancer plugs.
Furthermore, an umbrella cover (1) and an elastic support (71) are fixed on the guide wire (7), and the elastic support (71) is in the shape of an umbrella rib and consists of a plurality of foldable mechanical rods. The front end (711) of the elastic support is fixed on the guide wire (7), the rear end (712) of the elastic support is fixed on the micro baffle plate (73), the guide wire (7) passes through the inside of the elastic support (71) and is wound by the micro spring (72), and the original length of the micro spring (72) is equivalent to the distance from the front end (711) to the rear end (712) of the elastic support (71) in the closed state. The miniature baffle (73) is an annular cylinder and can freely slide back and forth on the guide wire (7), specifically, the outer diameter of the miniature baffle (73) is slightly larger than the inner diameter of the inner tube (4), and the inner diameter of the miniature baffle (73) is slightly smaller than the diameter of the miniature spring (72); therefore, when the guide wire (7) moves backwards, the micro baffle plate (73) and the micro spring (72) are clamped at the front end opening of the inner tube (4), the micro spring (72) is compressed to shrink, the distance between the front end (711) of the elastic support and the rear end (712) of the elastic support is reduced, the mechanical rod in the elastic support (71) is gradually folded, the umbrella cover (1) is opened into a net bag shape under the mechanical action, and the cancer plug is covered in the net bag shape, so that the cancer plug is captured.
Preferably, the position of the front end (711) of the elastic support fixed on the guide wire (7) is at least distant from the front end opening of the inner tube (4) by the original length of the micro spring (72), and the position of the umbrella cover (1) fixed on the guide wire (7) is slightly closer to the cancer plug position than the front end (711) of the elastic support, so that the umbrella cover (1) can be completely opened just when the elastic support (71) is fully folded.
Further, the far-end baffle plate (3) is fixed outside the suction tube (2) and is closely attached to the inner wall of the blood vessel. The far-end baffle (3) is of a net structure and is of a spiral appearance, two ends of the fallen cancer plug are plugged together with the umbrella cover (1), and the cancer plug is prevented from being spread to the far end to form a far-end plug. The spiral appearance of the far-end baffle plate (3) can increase the pressure area of the blood vessel wall, reduce the pressure, avoid damaging the blood vessel to rupture, and the far-end baffle plate (3) has a multi-layer spiral structure, can leak and repair the fallen cancer plug, and increases the effectiveness of blocking the cancer plug; the baffle is provided with holes with different sizes, so that blood can pass through conveniently, and the outermost ring is in an intermittent arc shape, so that the resistance of the device in moving in a blood vessel cavity can be reduced, and the damage to the blood vessel wall can be avoided.
When the cancer thrombus taking device is used, firstly, cancer thrombus can be positioned through B ultrasonic or X rays, then, in the minimally invasive surgery process, the guide wire (7) is pushed forward by pressing the hydraulic rod (62) under the extrusion action of the latch (64), and the guide wire (7) is delivered to the cancer thrombus position; then, a conical electrotome (741) on a wire guiding head (74) at the front end of the guide wire (7) generates electric spark under the effect of tip discharge, so as to realize the cauterization and puncture of cancer plugs; then, the hydraulic rod (62) is continuously pressed, the guide wire (7) is forwards pushed by utilizing the extrusion action of the latch (64), the guide wire (7) drives the umbrella cover (1) to pass through the cancer plug together, at the moment, the umbrella cover (1) and the elastic support (71) are in a contracted state, and the appearance is smaller, so that the guide wire (7) and the umbrella cover (1) cannot damage the cancer plug when passing through the cancer plug, and the cancer plug is separated from or spread in advance from the pipe wall with the cancer plug; then, the guide wire is pulled backwards through the handle (6) until the micro baffle plate (73) and the micro spring (72) are clamped at the front end opening of the inner tube (4), the micro spring (72) is compressed and contracted, the distance between the front end (711) of the elastic support and the rear end (712) of the elastic support is reduced, the mechanical rod in the elastic support (71) is gradually folded, the umbrella cover (1) is converted into an initial unfolding state from a contracted state under the mechanical action until the umbrella cover (1) is unfolded until the inner diameter of the opening of the umbrella cover is larger than the diameter of the cancer plug, the unfolded umbrella cover (1) is positioned at the front end of the cancer plug, and when the umbrella cover (1) is driven by the guide wire (7) to move towards one side where the cancer plug is positioned, the front end of the cancer plug can be sleeved by the umbrella cover (1) so as to cover the cancer plug. Then, the umbrella cover (1) is driven to move towards the front end opening of the inner tube (4) through the guide wire (7), and at the moment, the far-end baffle (3) and the umbrella cover (1) together realize the two-end blocking of the fallen cancer plug, so that the cancer plug is prevented from being spread to the far end to form a far-end plug; next step of aspiration, under the action of the aspiration device connected with the aspiration orifice (5), cancer thrombus particles are sucked out of the blood vessel through the accommodating cavity between the inner wall of the aspiration tube (2) and the outer wall of the inner tube (4), and leave the body through the aspiration orifice (5).
Preferably, the diameter of the canopy (1) and the distal end flap (3) in the deployed state is in the range of 8mm to 20mm. Therefore, even if cancer plugs grow in the blood vessels with smaller diameters such as the portal vein, the superior mesenteric vein and the splenic vein, the device can position the cancer plugs by means of B ultrasonic or X rays under the state of no operation, and the cancer plugs are taken out by using the cancer plug taking device through minimally invasive operation, so that the problem that common instruments are difficult to clamp the cancer plugs with smaller diameters is solved. Preferably, the umbrella cover (1) and the distal baffle (3) can be set to be 8mm, 10mm, 12mm, 14mm, 16mm, 20mm and other specifications so as to adapt to the pipe walls of patients with different diameters, and can be set to be other specifications as required.
It is apparent that the above examples are merely illustrative of the present invention and are not limiting of the embodiments of the present invention. Other variations or modifications of the above teachings will be apparent to those of ordinary skill in the art. It is not necessary here nor is it exhaustive of all embodiments. And obvious changes and modifications which come within the spirit of the invention are desired to be protected.

Claims (1)

1. A hepatic carcinoma portal vein cancer embolus capturing device, which comprises an umbrella cover (1); a suction pipe (2); a distal baffle (3); an inner tube (4); a suction nozzle (5); a handle (6); a guide wire (7); the device is characterized in that the inner tube (4) is connected with the handle (6) through a groove, a guide wire (7) penetrates through the hollow columnar structure of the inner tube (4), and the guide wire (7) can move back and forth in the inner tube (4); the handle (6) is composed of a bottom plate (61), a hydraulic rod (62), a cover plate (63), a latch (64), a shaft (65) and a supporting frame (66); the front end of the cover plate (63) is connected with a supporting frame (66) through a shaft (65), the rear end of the cover plate (63) is connected with a hydraulic rod (62) through the shaft (65), and the supporting frame (66) and the bottom end of the hydraulic rod (62) are fixed on the bottom plate (61); the lower end of the cover plate (63) is fixedly provided with a latch (64), and the latch (64) forwards pushes the guide wire (7) through extrusion in the process of pressing the hydraulic rod (62) to deliver the guide wire (7) to a cancer plug part; a semicircular groove is formed in the middle of the bottom plate (61), the front half part of the groove is used for fixing the inner tube (4), and the rear half part of the groove is used for pushing the guide wire (7); a conical electrotome (741) and a miniature conductive wire (742) are arranged on a wire guiding head (74) at the front end of the guide wire (7), and the conical electrotome (741) can realize the puncture of a cancer plug under the action of current; the rear end of the yarn guiding head (74) is provided with an umbrella cover (1), and an elastic bracket (71) is arranged inside the umbrella cover (1); the front end of the elastic support (71) is fixed on the guide wire (7), a micro spring (72) is arranged in the elastic support to maintain the closed state of the umbrella cover (1) and the elastic support (71) in the forward pushing process, and the annular micro baffle (73) at the rear end can slide on the guide wire; when the guide wire (7) is pulled backwards, the micro baffle (73) with larger diameter relative to the inner tube is clamped at the opening of the inner tube (4), and the elastic bracket (71) is opened together with the umbrella cover (1) to cover the cancer plug inside; the far-end baffle (3) is fixed outside the suction tube (2), so that the cancer plug can be blocked, the spiral circular appearance of the far-end baffle (3) can reduce the pressure of the far-end baffle on the wall of a blood vessel, and the blood vessel is prevented from being damaged; the far-end baffle is provided with holes with different sizes, so that blood can pass through the far-end baffle conveniently, and the outermost ring is in an intermittent arc shape, so that the resistance when moving in the blood vessel cavity can be reduced; the inner tube (4) is nested in the suction tube (2) with a certain gap left to suck the captured portal vein cancer plug out of the body.
CN202210241950.8A 2022-03-11 2022-03-11 Hepatic carcinoma portal vein cancer suppository capturing device Active CN114569235B (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1277064A (en) * 1999-06-10 2000-12-20 上海东方肝胆外科医院 Supersonic melting system for treating liver cancer and portal vein cancer
CN109350181A (en) * 2018-11-21 2019-02-19 中国医科大学 A kind of taking thrombus device
CN110801268A (en) * 2019-11-11 2020-02-18 广州华科盈医疗科技有限公司 Cancer embolus taking device
CN213526752U (en) * 2020-05-25 2021-06-25 四川大学华西医院 Spinal abscess puncture drainage washing unit

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220054153A1 (en) * 2020-08-22 2022-02-24 Sheri Albers Device and method for treatment of deep vein thrombosis and pulmonary embolism

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1277064A (en) * 1999-06-10 2000-12-20 上海东方肝胆外科医院 Supersonic melting system for treating liver cancer and portal vein cancer
CN109350181A (en) * 2018-11-21 2019-02-19 中国医科大学 A kind of taking thrombus device
CN110801268A (en) * 2019-11-11 2020-02-18 广州华科盈医疗科技有限公司 Cancer embolus taking device
CN213526752U (en) * 2020-05-25 2021-06-25 四川大学华西医院 Spinal abscess puncture drainage washing unit

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