CN114558076A - Pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream and preparation method thereof - Google Patents

Pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream and preparation method thereof Download PDF

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CN114558076A
CN114558076A CN202210290138.4A CN202210290138A CN114558076A CN 114558076 A CN114558076 A CN 114558076A CN 202210290138 A CN202210290138 A CN 202210290138A CN 114558076 A CN114558076 A CN 114558076A
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extract
oil
cattail pollen
percentage
weight
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王越
韩晨馨
王兴琦
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Shandong Vianor Biotech Co ltd
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Shandong Vianor Biotech Co ltd
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
    • A—HUMAN NECESSITIES
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention discloses a pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream which comprises propolis, molecular distillation sesame oil, cosmetic-grade corn oil, coconut oil, cetyl alcohol, beeswax, deep sea fish oil, edible glyceryl monostearate, honeycomb element extract, nidus vespae extract, cattail pollen extract, spiny seaweed extract, belladonna extract, liquorice fluid extract, aloe vera, phellodendron extract, Chinese herbal medicine extracts such as sappan wood, cicada slough and the like, T-20 (polysorbate-20), alkyl glucoside (C12-18) and deionized water. Simultaneously discloses a preparation method of the pure natural cattail pollen honeycomb element skin wound hemostatic and analgesic cream. The invention can be directly applied to the damaged part of the skin wound to stop bleeding, relieve pain and promote the wound healing, and solves the problem that the prior art can not meet the special requirements of the family self-treatment of the skin wound or the external rehabilitation after the operation.

Description

Pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream and preparation method thereof
Technical Field
The invention relates to a cream, in particular to a pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream and a preparation method thereof, belonging to the technical field of traditional Chinese medicine creams.
Background
Skin trauma generally refers to the destruction of skin tissue and the possible systemic reactions that occur as a result of various factors. In recent years, the external traditional Chinese medicine has a great progress in treating various types of skin wounds, more and more traditional Chinese medicines are used in clinic, and a better clinical effect is achieved, and people gradually pay attention to the function of the traditional Chinese medicine in treating the wounds
In traditional Chinese medicine, the contents of wound healing can be summarized in the category of incised wound, the contents are rich, the history is long, and doctors of all ages also accumulate certain clinical experience. The traditional Chinese medicine is externally used for promoting wound healing, has unique curative effect, takes the main treatment principles of promoting qi and activating blood circulation, promoting the growth of new tissue, eliminating dampness and recovering pus, removing pus and muscle, promoting the healing of acerbity and promoting tissue regeneration and healing wound as well as exerts multi-target, multi-link and multi-level comprehensive regulation and control effects on main influence factors of wound healing, and has obvious effect.
In clinical skin trauma applications, an ointment is the most common dosage form. The ointment is externally applied to the wound, and the isolation effect can effectively avoid external bacterial infection and stimulation, promote the improvement of local blood pressure circulation of the affected part and the repair and regeneration of wound tissues as soon as possible.
In recent years, the external medicine for treating skin wounds has been developed to a certain extent. However, due to the lack of special varieties, the special requirements of home self-treatment of skin wounds or external rehabilitation after operation cannot be met.
Disclosure of Invention
The invention aims to overcome the defects in the prior art and provides the pure natural cattail pollen honeycomb element skin wound hemostatic and analgesic cream and the preparation method thereof.
In order to solve the problems, the invention adopts the following technical scheme: a pure natural cattail pollen honeycomb element skin wound hemostasis analgesic cream comprises 24-24.5% of oil phase and 75.5-76% of water phase according to weight percentage;
the oil phase comprises the following components in percentage by weight: 1.5-2.0% of propolis, 1.5-2.0% of molecular distilled sesame oil, 7.0-8% of cosmetic-grade corn oil, 2-3% of coconut oil, 4.0-5% of cetyl alcohol, 1.5-2% of beeswax, 1.5-2% of deep sea fish oil and 2.0-2.5% of edible glyceryl monostearate;
the water phase comprises the following components in percentage by weight: 2.0-2.5% of beehive extract, 1.5% of nidus vespae extract, 3.0-3.5% of cattail pollen extract, 1.5% of spiny cabbage extract, 1.5-2.5% of belladonna extract, 1.5-3.0% of liquorice fluid extract, 2.5-3.0% of aloe barbadensis, 1.0-1.5% of phellodendron extract, 1.0-1.5% of sappan wood extract, 0.5-1.0% of cicada slough extract, 1.5% of T-201.0-1.5% of alkyl glucoside and 51.5-56.0% of deionized water.
The following is a further optimization of the present invention to the above scheme: a pure natural pollen Typhae honeycomb essence cream for stopping bleeding and relieving pain of skin wound comprises oil phase 24.5% and water phase 75.5%;
the oil phase comprises the following components in percentage by weight: 1.5% of propolis, 2.0% of molecular distilled sesame oil, 8% of cosmetic-grade corn oil, 2% of coconut oil, 5% of cetyl alcohol, 2% of beeswax, 2% of deep sea fish oil and 2.0% of edible glyceryl monostearate;
the water phase comprises the following components in percentage by weight: 2.0% of beehive extract, 1.5% of nidus vespae extract, 3.0% of cattail pollen extract, 1.5% of spiny seaweed extract, 1.5% of belladonna extract, 1.5% of liquorice fluid extract, 3.0% of aloe barbadensis, 1.0% of phellodendron extract, 1.5% of sappan wood extract, 0.5% of cicada slough extract, T-201.0%, 1.5% of alkyl glucoside and 56.0% of deionized water.
And (4) further optimizing: a pure natural cattail pollen honeycomb element skin wound hemostasis analgesic cream comprises 24% of oil phase and 76% of water phase by weight percent;
the oil phase comprises the following components in percentage by weight: 2.0% of propolis, 1.5% of molecular distilled sesame oil, 8.0% of cosmetic-grade corn oil, 3.0% of coconut oil, 4.5% of cetyl alcohol, 1.5% of beeswax, 1.5% of deep sea fish oil and 2.0% of edible glyceryl monostearate;
the water phase comprises the following components in percentage by weight: 2.5 percent of beehive extract, 1.5 percent of nidus vespae extract, 3.5 percent of cattail pollen extract, 1.5 percent of spiny pricklyash root extract, 2.5 percent of belladonna extract, 2.5 percent of liquorice fluid extract, 2.5 percent of aloe barbadensis, 1.5 percent of phellodendron extract, 1.0 percent of sappan wood extract, 1.0 percent of cicada slough extract, T-201.5 percent, 1.5 percent of alkyl glucoside and 53.0 percent of deionized water.
The invention also discloses a pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream which comprises 24.5 percent of oil phase and 75.5 percent of water phase by weight percent;
the oil phase comprises the following components in percentage by weight: 2.0% of propolis, 2.0% of molecular distilled sesame oil, 7.0% of cosmetic corn oil, 3.0% of coconut oil, 4.0% of cetyl alcohol, 2.0% of beeswax, 2.0% of deep sea fish oil and 2.5% of edible glyceryl monostearate;
the water phase comprises the following components in percentage by weight: 2.5% of beehive extract, 1.5% of nidus vespae extract, 3.5% of cattail pollen extract, 1.5% of spiny prickly ash extract, 2.5% of belladonna extract, 3.0% of liquorice fluid extract, 3.0% of aloe barbadensis, 1.5% of phellodendron extract, 1.5% of sappan wood extract, 1.0% of cicada slough extract, T-201.0%, 1.5% of alkyl glucoside and 51.5% of deionized water.
Simultaneously discloses a preparation method of the pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream, which comprises the following steps:
(1) weighing raw materials of each component in the oil phase according to the weight percentage, adding the raw materials into a preheating tank, controlling the temperature to be between 70 and 80 ℃, and starting stirring until the oil phase is completely melted when the oil phase is melted;
(2) weighing raw material components and deionized water in the water phase according to the weight percentage, adding the raw material components and deionized water into a water phase preheating tank, heating, starting stirring, and keeping the temperature between 70 ℃ and 80 ℃ to completely dissolve the raw materials;
(3) keeping the temperature of the oil phase and the water phase, pressing the oil phase and the water phase into a homogenizing emulsifier through a pipeline with a filter screen, mixing, homogenizing and emulsifying to obtain the product.
The excellent effects of the present invention are as follows:
1. the traditional Chinese medicine of cattail pollen and honeycomb element are compounded, the application of the traditional Chinese medicine of cattail pollen and honeycomb element in the cream for treating skin wounds is not reported, and the research of the cream in the patent opens a creative new mode;
the pollen Typhae is an excellent hemostatic, and is dried pollen of Typha angustifolia, Typha orientalis or congeneric plants of Typhaceae;
pollen Typhae for treating traumatic hemorrhage can be used alone for external wound, has effects of promoting blood circulation, removing blood stasis, and treating stranguria, and can be used for external treatment of traumatic injury, pollen Typhae has hemostatic effect, and has hemostatic effect without blood stasis;
the cattail pollen has the efficacy of activating blood, is clinically used for treating various pains caused by blood stasis, can treat ear purulence, water flowing or vulvar pruritus caused by aphtha or in-ear eczema and otitis media, and is a good medicine for stopping bleeding and easing pain of skin wounds and promoting wound healing.
2. The honeycomb element, the nidus vespae and the propolis can naturally ease pain and promote tissue regeneration, and play a synergistic effect of easing pain, resisting inflammation and promoting wound healing in the cream;
the honeycomb element is prepared by extracting effective components from honeycomb and refining, can be used for treating sore carbuncle pyogenic infections, acute mastitis swelling and pain, scrofula subcutaneous nodule, stubborn tinea, cancerous swelling and pain and the like, and has the effects of resisting inflammation, easing pain, promoting blood coagulation, reducing blood pressure, expanding blood vessels, strengthening heart, resisting cancer, resisting bacteria, reducing temperature, expelling ascarid and winged insect and is commonly used for treating various diseases such as pyogenic infection, acute mastitis, neurodermatitis, toothache, dysentery, enuresis, pertussis, chronic bronchitis and the like;
nidus Vespae extract has effects of dispelling rash, pruritus and relieving pain; swelling-eliminating rose venom for treating pyogenic infection; killing parasites to relieve itching, and relieving arthralgia due to wind-heat; carbuncle, deep-rooted carbuncle and malignant sore; scrofula (eczema); swelling and pain of the throat and tongue; hemorrhoids and fistula; wind itching; intractable skin tinea; the nidus Vespae added into the cream has certain curative effects on traumatic infection, postoperative wound infection, furuncle, carbuncle, scald, cellulitis, subcutaneous gangrene of newborn and the like, is particularly more effective on gangrene (ulcerated) and suppurative sore surfaces, has the functions of removing necrosis, promoting granulation, diminishing inflammation, relieving pain and the like, and can promote the wound to be as soon as possible;
propolis is a traditional natural medicine, and has wide pharmacological activity and wound healing effect;
the application history of the propolis in Europe has been over 2000 years, and the propolis is currently collected in pharmacopoeia of the people's republic of China, and the functions and the main treatment of the propolis are determined as follows: tonifying deficiency, eliminating turbid fat, and relieving diabetes; the external use detoxifies detumescence, astringes and promotes granulation, and is used for treating body deficiency, senilism, hyperlipoidemia and diabetes; the propolis has excellent anti-inflammatory and bactericidal effects, so that more and more scientists begin to apply the propolis to the field of wound healing research, and the addition of the propolis into the cream ensures that the cream has the effects of detoxifying, healing sore, promoting granulation and relieving pain, has good treatment effects on skin wounds and postoperative wounds, is commonly used for rehabilitation treatment of unhealed ulcer, ecthyma erosion, traumatic ulceration and burn and scald, and has good effects on anesthesia and analgesia.
3. Effect and action of Roxburgh herbs
The spiny vegetable traditional Chinese medicine is named as herba cephalanoploris, is a high-quality wild vegetable, has strong adaptability, can grow under any weather conditions, is common weed, is sweet and cool in nature and tastes cool, enters heart, liver, lung and stomach channels, has the effects of cooling blood and stopping bleeding and clearing heat and toxic materials, has the effect of cooling blood and stopping bleeding, is mainly used by causing local vasoconstriction and inhibiting fibrinolysis, has good effects of clearing heat and removing toxicity, and can be used for treating heat-toxin sore swelling and traumatic hemorrhage.
4. Belladonna grass extract with excellent pain relieving and granulation promoting effects
Belladonna grass has the functions of inhibiting secretion, anaesthetizing, relieving pain, promoting blood circulation and removing blood stasis, and can be used for treating traumatic injury, carbuncle, sore and pyogenic infections, and is easy to astringe and heal wound surfaces.
5. Licorice plays an important role in the formula
Glycyrrhizin and licoisoflavone compounds in Glycyrrhrizae radix have effect in inhibiting HIV proliferation; glycyrrhrizae radix has antivirus effect, and Glycyrrhrizae radix alcohol extract and sodium glycyrrhetate have antibacterial effect; the liquorice has anti-inflammatory effect, has good curative effect on patients suffering from skin ulcer, rhagadia manus et pedis, solar dermatitis, contact dermatitis and frostbite ulcer complicated infection by modern clinical external application, has the advantages of fading of red swelling, stopping seepage and healing of erosion face in 1-4 days of treating contact dermatitis generally, and also has good effect on treating allergic dermatitis.
6. Aloe has excellent skin injury repairing effect
The aloe gel has the effects of protecting skin, promoting wound healing, diminishing inflammation and sterilizing, has a plurality of external effects and efficacies, can protect skin on one hand, and can diminish inflammation and sterilize on the other hand, when the juice of the aloe is prepared into a polysaccharide preparation for skin or other tissue wounds and the like, the aloe gel has good effects of moisturizing, preventing sunburn and promoting wound healing, has good skin-care effect, can not only replenish moisture for the skin, but also prevent aging, can relieve nerves, calm the skin, kill bacteria and well keep moisture due to good bacteriostatic effect, can lead the skin to become tender due to insisting on, simultaneously has a certain spot-lightening effect, contains a certain whitening component and a certain collagen component, can repair damaged skin and lead the skin to become plump, Reducing the generation of wrinkles.
7. The phellodendron bark has obvious effects of detoxifying and treating sore
The golden cypress is a heat-clearing medicine, has the effects of clearing heat, drying dampness, purging fire, removing steam, detoxifying and treating sore, can detoxify and treat sore, and is clinically used for treating carbuncle ulcer and furuncle caused by excessive fire-heat toxin;
in Bencao Shiyi, it is indicated for treating herpes zoster, insect sore, dysentery, hematochezia and moth;
rihuazi Bencao states that "Anxin removes fatigue, cures bone steaming, washes liver, improves eyesight, tears, dry mouth, heart heat, kills infantile malnutrition worms, cures ascarid heartache, scabies, cures nose flood, intestinal wind, purges blood, and is divided into acute heat swelling and pain after that. "
8. Cicada slough
The medicine has the effects of resisting convulsion, calming, relieving fever, resisting allergy, suppressing immunity and relieving pain, can be used for treating acute and chronic tonsillitis, cough, night cry of infants, urticaria, various skin pruritus and other diseases, dispelling wind and removing heat, relieving sore throat, promoting eruption, removing nebula and relieving spasm, and is used for treating wind-heat type common cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion, nebula, convulsion and tetanus;
in a word, the pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream has excellent effects of promoting blood circulation to remove blood stasis, relieving swelling and pain, clearing heat and removing toxicity, and promoting tissue regeneration and healing, can effectively promote blood circulation of a wound part, promotes the penetration and absorption of medicaments in local tissues from the outside to the inside, and achieves the purposes of dredging channels and collaterals, promoting blood circulation to remove blood stasis and relieving pain; the medicine can directly contact with wound, and is beneficial to clearing heat, detumescence, removing putrefaction, promoting granulation, and promoting wound healing; in addition, the cattail pollen honeycomb element oil-in-water emulsifiable paste has the advantages of fine paste, excellent skin-friendly performance, easy coating after expansion, long detention time, easy absorption by wounds, good stability, naturalness, safety and no toxic or side effect.
The invention has excellent effects of stopping bleeding, easing pain, resisting inflammation, eliminating decay, promoting wound healing and repairing wound surface, and can be widely applied to the treatment of skin wound and the rehabilitation treatment of auxiliary operation wound surface;
the invention is composed of natural substrate raw materials, endows the cream with excellent skin affinity, softness, tastelessness, smoothness, no stimulation, is suitable for all groups including pregnant women, and can be used in large area;
the ointment is prepared by adopting a mild surface emulsifier, is fine and smooth, can be directly applied to wounds, has a good isolation effect, and is safe and non-irritant;
the invention is easy to coat in oil-in-water dosage form; can be effectively fused with the wound and is convenient to carry; does not pollute clothes, and is suitable for people of all ages.
The invention is further illustrated with reference to the following figures and examples.
Drawings
FIG. 1 is a result of testing physicochemical indexes of a pure natural pollen Typhae comb element cream for stopping bleeding and easing pain of skin wounds.
Detailed Description
Example 1, a pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream comprises 24.5 percent of oil phase and 75.5 percent of water phase by weight percent;
the oil phase comprises the following components in percentage by weight: 1.5% of propolis, 2.0% of molecular distilled sesame oil, 8% of cosmetic-grade corn oil, 2% of coconut oil, 5% of cetyl alcohol, 2% of beeswax, 2% of deep sea fish oil and 2.0% of edible glyceryl monostearate;
the water phase comprises the following components in percentage by weight: 2.0% of beehive extract, 1.5% of nidus vespae extract, 3.0% of cattail pollen extract, 1.5% of cephalanoplos chinensis (herba cephalanoploris) extract, 1.5% of belladonna extract, 1.5% of liquorice fluid extract, 3.0% of aloe vera, 1.0% of phellodendron extract, 1.5% of sappan wood extract, 0.5% of cicada slough, 1.0% of T-20 (polysorbate-20), 1.5% of alkyl glucoside (C12-18) and 56.0% of deionized water.
The preparation method of the pure natural cattail pollen honeycomb element skin wound hemostatic and analgesic cream comprises the following steps: (1) weighing raw materials of each component in the oil phase according to the weight percentage, adding the raw materials into a preheating tank, controlling the temperature to be between 70 and 80 ℃, and starting stirring until the oil phase is completely melted when the oil phase is melted;
(2) weighing raw material components and deionized water in the water phase according to the weight percentage, adding the raw material components and the deionized water into a water phase preheating tank, heating, starting stirring, and keeping the temperature between 70 ℃ and 80 ℃ to completely dissolve the raw materials;
(3) keeping the temperature of the oil phase and the water phase, pressing the oil phase and the water phase into a homogenizing emulsifier through a pipeline with a filter screen, mixing, homogenizing and emulsifying to obtain the product.
Example 2, a pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream, which comprises 24% of oil phase and 76% of water phase by weight percentage;
the oil phase comprises the following components in percentage by weight: 2.0% of propolis, 1.5% of molecular distilled sesame oil, 8.0% of cosmetic-grade corn oil, 3.0% of coconut oil, 4.5% of cetyl alcohol, 1.5% of beeswax, 1.5% of deep sea fish oil and 2.0% of edible glyceryl monostearate;
the water phase comprises the following components in percentage by weight: 2.5% of beehive extract, 1.5% of nidus vespae extract, 3.5% of cattail pollen extract, 1.5% of cephalanoplos chinensis (herba cephalanoploris) extract, 2.5% of belladonna extract, 2.5% of liquorice fluid extract, 2.5% of aloe vera, 1.5% of phellodendron extract, 1.0% of sappan wood extract, 0.5% of cicada slough extract, 1.5% of T-20 (polysorbate-20), 1.5% of alkyl glucoside (C12-18) and 53.0% of deionized water.
The preparation method of the pure natural cattail pollen honeycomb element skin wound hemostatic and analgesic cream comprises the following steps: (1) weighing raw materials of each component in the oil phase according to the weight percentage, adding the raw materials into a preheating tank, controlling the temperature to be between 70 and 80 ℃, and starting stirring until the oil phase is completely melted when the oil phase is melted;
(2) weighing raw material components and deionized water in the water phase according to the weight percentage, adding the raw material components and the deionized water into a water phase preheating tank, heating, starting stirring, and keeping the temperature between 70 ℃ and 80 ℃ to completely dissolve the raw materials;
(3) keeping the temperature of the oil phase and the water phase, pressing the oil phase and the water phase into a homogenizing emulsifier through a pipeline with a filter screen, mixing, homogenizing and emulsifying to obtain the product.
Example 3, a pure natural cattail pollen honeycomb element skin wound hemostatic and analgesic cream comprises 24.5% of oil phase and 75.5% of water phase by weight percentage;
the oil phase comprises the following components in percentage by weight: 2.0% of propolis, 2.0% of molecular distilled sesame oil, 7.0% of cosmetic-grade corn oil, 3.0% of coconut oil, 4.0% of cetyl alcohol, 2.0% of beeswax, 2.0% of deep sea fish oil and 2.5% of edible glyceryl monostearate;
the water phase comprises the following components in percentage by weight: 2.5% of beehive extract, 1.5% of nidus vespae extract, 3.5% of cattail pollen extract, 1.5% of cephalanoplos chinensis (herba cephalanoploris) extract, 2.5% of belladonna extract, 3.0% of liquorice fluid extract, 3.0% of aloe vera, 1.5% of phellodendron extract, 1.5% of sappan wood extract, 1.0% of cicada slough extract, 1.0% of T-20 (polysorbate-20), 1.5% of alkyl glucoside (C12-18) and 51.5% of deionized water.
The preparation method of the pure natural cattail pollen honeycomb element skin wound hemostatic and analgesic cream comprises the following steps: (1) weighing raw materials of each component in the oil phase according to the weight percentage, adding the raw materials into a preheating tank, controlling the temperature to be between 70 and 80 ℃, and starting stirring until the oil phase is completely melted when the oil phase is melted;
(2) weighing raw material components and deionized water in the water phase according to the weight percentage, adding the raw material components and the deionized water into a water phase preheating tank, heating, starting stirring, and keeping the temperature between 70 ℃ and 80 ℃ to completely dissolve the raw materials;
(3) keeping the temperature of the oil phase and the water phase, pressing the oil phase and the water phase into a homogenizing emulsifier through pipelines with filter screens respectively, mixing, homogenizing and emulsifying to obtain the product.
Example 4, the application method of the pure natural pollen typhae honeycomb element skin wound hemostasis and analgesia cream comprises the steps of dipping a little by a cotton stick or a cotton ball absorbent, and directly applying the cream to a wound or a ulcerated and rotten wound;
if bleeding occurs, the ointment can be dipped in cotton ball and then attached to the wound for staying, and after the bleeding stops, the ointment is taken again and applied again.
The honeycomb element Chinese herbal medicine component hemostatic and analgesic cream has excellent hemostatic, analgesic, antibacterial, wound-astringing and wound-healing promoting performances and good user feedback after being used by people of all ages, various skin wounds and postoperative groups, and is accepted and reputed by patients.
Performance testing
The performance detection of the pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream is carried out according to the QB/T1857-2013 cosmetic cream standard, and the quality and performance of the products of examples 1-3 can reach the standard requirements.
The test results of physical and chemical indexes of a pure natural pollen typhae honeycomb element skin wound hemostatic and analgesic cream are shown in figure 1.
A Chinese herbal medicine component hemostatic and analgesic cream of pollen typhae honeycomb element is prepared by taking pollen typhae, honeycomb element, nidus vespae and propolis as main analgesic and anti-inflammatory components and taking traditional Chinese herbal medicine extract of liquorice, belladonna, golden cypress, sappan wood, cicada slough and the like which are used for stopping bleeding, relieving pain and astringing wounds as auxiliary materials, relates to two aspects of medicine compatibility and paste matrix formula of medical theory, belongs to two different technical fields, the cattail pollen honeycomb element hemostatic and analgesic cream of the invention is successfully researched, has the functions of stopping bleeding, easing pain, resisting inflammation, astringing wound and assisting the recovery of skin wound after operation for consumers, has unique effect on the treatment of skin diseases such as sores and carbuncles, and the like, is successfully developed, the method can create good economic and social benefits for enterprises while bringing good news to people.

Claims (5)

1. A pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream is characterized in that: comprises 24 to 24.5 percent of oil phase and 75.5 to 76 percent of water phase according to weight percentage;
the oil phase comprises the following components in percentage by weight: 1.5-2.0% of propolis, 1.5-2.0% of molecular distilled sesame oil, 7.0-8% of cosmetic-grade corn oil, 2-3% of coconut oil, 4.0-5% of cetyl alcohol, 1.5-2% of beeswax, 1.5-2% of deep sea fish oil and 2.0-2.5% of edible glyceryl monostearate;
the water phase comprises the following components in percentage by weight: 2.0-2.5% of beehive extract, 1.5% of nidus vespae extract, 3.0-3.5% of cattail pollen extract, 1.5% of spiny cabbage extract, 1.5-2.5% of belladonna extract, 1.5-3.0% of liquorice fluid extract, 2.5-3.0% of aloe barbadensis, 1.0-1.5% of phellodendron extract, 1.0-1.5% of sappan wood extract, 0.5-1.0% of cicada slough extract, 1.5% of T-201.0-1.5% of alkyl glucoside and 51.5-56.0% of deionized water.
2. The pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream as claimed in claim 1, which is characterized in that: comprises 24.5 percent of oil phase and 75.5 percent of water phase according to weight percentage;
the oil phase comprises the following components in percentage by weight: 1.5% of propolis, 2.0% of molecular distilled sesame oil, 8% of cosmetic-grade corn oil, 2% of coconut oil, 5% of cetyl alcohol, 2% of beeswax, 2% of deep sea fish oil and 2.0% of edible glyceryl monostearate;
the water phase comprises the following components in percentage by weight: 2.0% of beehive extract, 1.5% of nidus vespae extract, 3.0% of cattail pollen extract, 1.5% of spiny seaweed extract, 1.5% of belladonna extract, 1.5% of liquorice fluid extract, 3.0% of aloe barbadensis, 1.0% of phellodendron extract, 1.5% of sappan wood extract, 0.5% of cicada slough extract, T-201.0%, 1.5% of alkyl glucoside and 56.0% of deionized water.
3. The pure natural cattail pollen honeycomb element skin wound hemostatic and analgesic cream as claimed in claim 1, which is characterized in that: comprises 24 percent of oil phase and 76 percent of water phase according to weight percentage;
the oil phase comprises the following components in percentage by weight: 2.0% of propolis, 1.5% of molecular distilled sesame oil, 8.0% of cosmetic-grade corn oil, 3.0% of coconut oil, 4.5% of cetyl alcohol, 1.5% of beeswax, 1.5% of deep sea fish oil and 2.0% of edible glyceryl monostearate;
the water phase comprises the following components in percentage by weight: 2.5% of beehive extract, 1.5% of nidus vespae extract, 3.5% of cattail pollen extract, 1.5% of spiny dock extract, 2.5% of belladonna extract, 2.5% of liquorice fluid extract, 2.5% of aloe barbadensis, 1.5% of phellodendron extract, 1.0% of sappan wood extract, 1.0% of cicada slough extract, T-201.5%, 1.5% of alkyl glucoside and 53.0% of deionized water.
4. The pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream as claimed in claim 1, which is characterized in that: comprises 24.5 percent of oil phase and 75.5 percent of water phase according to weight percentage;
the oil phase comprises the following components in percentage by weight: 2.0% of propolis, 2.0% of molecular distilled sesame oil, 7.0% of cosmetic corn oil, 3.0% of coconut oil, 4.0% of cetyl alcohol, 2.0% of beeswax, 2.0% of deep sea fish oil and 2.5% of edible glyceryl monostearate;
the water phase comprises the following components in percentage by weight: 2.5% of beehive extract, 1.5% of nidus vespae extract, 3.5% of cattail pollen extract, 1.5% of spiny seaweed extract, 2.5% of belladonna extract, 3.0% of liquorice fluid extract, 3.0% of aloe barbadensis, 1.5% of phellodendron extract, 1.5% of sappan wood extract, 1.0% of cicada slough extract, T-201.0%, 1.5% of alkyl glucoside and 51.5% of deionized water.
5. The method for preparing the pure natural cattail pollen honeycomb element skin wound hemostatic and analgesic cream as claimed in any one of claims 1 to 4, characterized in that: the method comprises the following steps: (1) weighing the raw materials of each component in the oil phase according to the weight percentage, adding the raw materials into an oil phase preheating tank, controlling the temperature to be between 70 and 80 ℃, and starting stirring until the oil phase is completely melted when the oil phase is melted;
(2) weighing raw material components and deionized water in the water phase according to the weight percentage, adding the raw material components and the deionized water into a water phase preheating tank, heating, starting stirring, and keeping the temperature between 70 ℃ and 80 ℃ to completely dissolve the raw materials;
(3) keeping the temperature of the oil phase and the water phase, pressing the oil phase and the water phase into a homogenizing emulsifier through pipelines with filter screens respectively, mixing, homogenizing and emulsifying to obtain the product.
CN202210290138.4A 2022-03-23 2022-03-23 Pure natural cattail pollen honeycomb element skin wound hemostasis and analgesia cream and preparation method thereof Pending CN114558076A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101596310A (en) * 2008-06-02 2009-12-09 彭强 A kind of artificial substrate membrane emulsifying paste that is used for wound repair
CN104940849A (en) * 2015-07-29 2015-09-30 青岛蓝盛洋医药生物科技有限责任公司 Traditional Chinese medicine preparation for treating boils through external application and preparation method of traditional Chinese medicine preparation
CN105963518A (en) * 2016-03-21 2016-09-28 经雷 External-use liniment for treating scald

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101596310A (en) * 2008-06-02 2009-12-09 彭强 A kind of artificial substrate membrane emulsifying paste that is used for wound repair
CN104940849A (en) * 2015-07-29 2015-09-30 青岛蓝盛洋医药生物科技有限责任公司 Traditional Chinese medicine preparation for treating boils through external application and preparation method of traditional Chinese medicine preparation
CN105963518A (en) * 2016-03-21 2016-09-28 经雷 External-use liniment for treating scald

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