CN114470524A - Portable high-frequency magnetic energy breast cancer auxiliary therapeutic apparatus and use method thereof - Google Patents
Portable high-frequency magnetic energy breast cancer auxiliary therapeutic apparatus and use method thereof Download PDFInfo
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Abstract
The invention discloses a portable high-frequency magnetic energy breast cancer auxiliary therapeutic apparatus and a using method thereof, and relates to the technical field of medical instruments. The invention discloses a magnetic energy breast cancer auxiliary therapeutic apparatus, which comprises a magnetic field generating coil group, a magnetic field mode controller and a magnetic field generating driver; the magnetic field generating coil group is fixedly arranged in the bra and can generate an alternating magnetic field with preset frequency and intensity under the cooperative control of the magnetic field mode controller and the magnetic field generating driver. The ultrasonic scanning device also comprises an ultrasonic positioner which can perform ultrasonic scanning on the chest and provide guidance basis for positioning and mounting the magnetic field generating coil assembly. The intelligent tumor treatment system further comprises a central controller, intelligent analysis can be carried out according to the tumor information scanned by the ultrasonic positioner, a control instruction with specific time sequence and strength can be generated according to preset program information, and the frequency and the strength of the alternating magnetic field generated by the magnetic field generating coil set are more beneficial to auxiliary treatment.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a portable high-frequency magnetic energy breast cancer auxiliary therapeutic apparatus and a using method thereof.
Background
The changing magnetic field has obvious effect on human body and other organisms, and can be used for intervening and treating various diseases of the organisms by utilizing the action of the magnetic field. The variable magnetic field therapy apparatus is a device which uses a magnetic field generating device such as an alternating current drive coil as a magnetic source, generates a magnetic field, and exposes the magnetic field to a part to be treated of a living body to destroy cell division, thereby inhibiting tumor growth in a regional and non-invasive manner.
Breast cancer is a cancer that begins with epithelial cells lining organs and tissues such as the breast, and other types of cancer may also occur in the breast, such as sarcomas, which originate from cells in muscle, fat or connective tissue. Cancer at an early and optimal stage of treatment occurs in cancerous tissue structures in specific regions within the tissue of the breast. Thus, the application of a particular treatment regime with a high concentration in the region of cancerous tissue may serve as an adjunct to the treatment.
Disclosure of Invention
The invention aims to provide a magnetic energy breast cancer auxiliary therapeutic apparatus and a using method thereof, and provides a more convenient auxiliary therapeutic means for breast cancer patients.
In order to achieve the above object, an embodiment of the present invention provides a magnetic energy breast cancer auxiliary therapeutic apparatus, which includes a magnetic field generating coil set, a magnetic field mode controller, and a magnetic field generating driver;
the magnetic field generating coil set comprises a plurality of circular coils and is used for generating an alternating magnetic field with preset frequency and intensity;
the magnetic field mode controller is used for sending a control instruction with preset time sequence and strength to the magnetic field generation driver and generating a control signal;
the magnetic field generation driver is used for receiving the control signal generated by the magnetic field mode controller and sending a driving signal to the circular coil according to the control signal so as to drive the coil to generate an induction magnetic field with corresponding frequency and intensity.
Preferably, the magnetic energy breast cancer auxiliary therapeutic apparatus further comprises an ultrasonic positioner, wherein the ultrasonic positioner is used for carrying out ultrasonic scanning on the breast to obtain tumor information and providing a guidance basis for positioning and installing the magnetic field generating coil set.
Preferably, the magnetic energy breast cancer auxiliary therapeutic apparatus further comprises a central controller, wherein the central controller is used for acquiring the tumor information and generating control instruction information according to the tumor information; the control instruction information includes control instructions of a particular timing and strength.
Preferably, the magnetic field generating coil set comprises 4 circular coils, and the coil center points of the 4 circular coils are respectively located at four vertexes of a square.
Preferably, the effective diameter of the round coil is 50-70mm, the number of turns is 4-10 turns, the round coil is formed by winding a copper wire, and the size of the copper wire is 2-4 square millimeters.
The embodiment of the invention also provides a using method of the magnetic energy breast cancer auxiliary therapeutic apparatus, which comprises the following steps:
the magnetic field mode controller acquires a control instruction of a preset time sequence and intensity and generates a control signal;
the magnetic field generation driver receives the control signal generated by the magnetic field mode controller and sends a driving signal to the circular coil according to the control signal;
the circular coil generates an alternating magnetic field with corresponding frequency and intensity according to the driving signal.
Preferably, the use method of the magnetic energy breast cancer therapeutic aid further comprises the following steps:
the ultrasonic positioner carries out ultrasonic scanning on the chest to obtain tumor information and provides guidance basis for positioning and mounting the magnetic field generating coil assembly.
Preferably, the use method of the magnetic energy breast cancer therapeutic aid further comprises the following steps:
the central controller acquires the tumor information and generates control instruction information according to the tumor information; the control instruction information includes control instructions of a particular timing and strength.
The embodiment of the invention also provides computer terminal equipment which comprises one or more processors and a memory. A memory coupled to the processor for storing one or more programs; when the one or more programs are executed by the one or more processors, the one or more processors implement the use method of the magnetic energy breast cancer therapeutic aid according to any one of the above embodiments.
The embodiment of the invention also provides a computer-readable storage medium, on which a computer program is stored, and when the computer program is executed by a processor, the method for using the magnetic energy breast cancer therapeutic assistant is implemented as described in any one of the above embodiments.
Compared with the prior art, the invention has the following beneficial effects:
the invention discloses a magnetic energy breast cancer auxiliary therapeutic apparatus, which comprises a magnetic field generating coil group, a magnetic field mode controller and a magnetic field generating driver; the magnetic field generating coil group is fixedly arranged in the bra and can generate an alternating magnetic field with preset frequency and intensity under the cooperative control of the magnetic field mode controller and the magnetic field generating driver.
The magnetic energy breast cancer auxiliary therapeutic apparatus disclosed by the invention further comprises an ultrasonic positioner, and the ultrasonic positioner can perform ultrasonic scanning on the breast and provide a guidance basis for positioning and installing the magnetic field generating coil group.
The magnetic energy breast cancer auxiliary therapeutic apparatus disclosed by the invention also comprises a central controller, can perform intelligent analysis according to tumor information scanned by the ultrasonic positioner, and generates a control instruction with specific time sequence and strength according to preset program information, so that the frequency and the strength of an alternating magnetic field generated by the magnetic field generating coil set are more beneficial to auxiliary treatment.
Drawings
In order to more clearly illustrate the technical solution of the present invention, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a schematic structural diagram of a magnetic energy breast cancer therapeutic apparatus according to an embodiment of the present invention;
fig. 2 is a schematic structural diagram of a magnetic field generating coil assembly according to an embodiment of the present invention;
FIG. 3 is a schematic diagram of a circular coil according to an embodiment of the present invention;
FIG. 4 is a schematic diagram of an independent driving of a magnetic energy breast cancer therapeutic apparatus according to an embodiment of the present invention;
fig. 5 is a schematic diagram of a driving circuit of a magnetic energy breast cancer therapeutic apparatus according to an embodiment of the present invention;
fig. 6 is a schematic structural diagram of a computer terminal device according to an embodiment of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be understood that the step numbers used herein are for convenience of description only and are not used as limitations on the order in which the steps are performed.
It is to be understood that the terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used in the specification of the present invention and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.
The terms "comprises" and "comprising" indicate the presence of the described features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof.
The term "and/or" refers to and includes any and all possible combinations of one or more of the associated listed items.
Among alternating magnetic fields, low frequency magnetic fields below 1kHz can stimulate nerves, muscles, heart and other tissues by cell membrane depolarization (transcranial magnetic stimulation is one of the most widely used low frequency magnetic stimulation applications). When the frequency of the alternating magnetic field is increased above 1kHz, the stimulation effect gradually diminishes, because the response time of the excitable process of the cell is too slow to follow higher frequencies. High frequency magnetic fields above 1MHz generate heat due to dielectric losses from cell membrane rupture and may lead to cell death by electroporation and this effect is mainly manifested as thermal effects and is determined mainly by the magnetic field strength. Therefore, the frequencies commonly used in radio frequency oncology medical treatments are in the MHz-GHz range, utilizing mainly the thermal effect of the magnetic field.
The field alternation of the medium frequency magnetic fields is too fast to cause biological tissue irritation and they generate very little heat. The medium frequencies (100kHz-500kHz) do not stimulate nerves, muscles and tissues, nor generate heat because their frequency range is relatively high and intensity is low. The medium frequency magnetic field generates an induction magnetic field and an electric field in the tumor and cancerous tissue region by induction, and the induced electric field can generate force effect on polarized molecules and particles of the tissue to interfere mitosis of tumor and cancerous tissue cells, so that cell division is interrupted and stopped, the tumor and cancerous tissue cells can be killed, the effect of treating the tumor and cancer is achieved, and normal tissue cells are not adversely affected. The magnetic energy breast cancer auxiliary therapeutic apparatus provided by the invention generates an alternating magnetic field with the frequency of 150-350KHz and the intensity of 0.2-5mT, can better distinguish dividing cells, can selectively destroy the dividing cells and has no influence on non-dividing cells.
Referring to fig. 1-3, the magnetic energy breast cancer therapeutic apparatus includes a magnetic field generating coil assembly 10, a magnetic field mode controller 20 and a magnetic field generating driver 30; the magnetic field generating coil assembly 10 comprises a plurality of circular coils 11 for generating alternating magnetic fields with preset frequency and intensity; the magnetic field generating coil group 10 is fixedly arranged in the bra; a magnetic field pattern controller 20 for sending a control command with a preset timing and intensity to the magnetic field generating driver 30 to generate a control signal; and a magnetic field generation driver 30 for receiving the control signal generated by the magnetic field pattern controller 20 and sending a driving signal to the circular coil 11 according to the control signal to drive the coil to generate an induced magnetic field with corresponding frequency and intensity.
The magnetic field mode controller 20 is externally provided with a plurality of mode control buttons for the user to adjust the magnetic field, including a frequency selection button, a waveform selection button, an intensity adjustment button, a switch button, and the like. The switching of the frequency selection key, the waveform selection key and the intensity adjustment key all enables control signals under preset control instructions of different time sequences and intensities to be sent to the magnetic field generation driver 30, the magnetic field generation driver 30 generates corresponding driving signals according to the control signals, and the driving coils generate induction magnetic fields with corresponding frequencies and intensities. The magnetic field generating driver 30 receives the control signal generated by the magnetic field pattern controller 20, and generates a driving current signal for each coil at a specific timing based on the control signal, so as to drive the circular coil 11 of the magnetic field generating coil assembly 10 to generate an induced magnetic field at a specific frequency and strength. The magnetic field mode controller can respectively realize that each single circular coil generates induction magnetic fields with different frequencies and intensities.
In one embodiment, the magnetic breast cancer assistant therapeutic apparatus further includes an ultrasonic positioner 40, and the ultrasonic positioner 40 is configured to perform ultrasonic scanning on the breast to obtain tumor information, and provide guidance for positioning and installing the magnetic field generating coil assembly 10.
In one embodiment, the magnetic energy breast cancer therapeutic apparatus further includes a central controller 50, where the central controller 50 is configured to obtain tumor information and generate control instruction information according to the tumor information; the control instruction information includes control instructions of a particular timing and strength.
In one embodiment, the ultrasound positioner 40 performs an ultrasound scan on the breast to obtain tumor information, and a simple watershed algorithm-based breast ultrasound image segmentation algorithm can be used to extract the size and position information of the tumor in the breast tumor ultrasound image. The central controller 50 generates control instruction information based on the tumor information. Wherein the tumor information comprises size and location information of the tumor. Specifically, the central controller 50 analyzes according to the size and position information of the tumor, matches a control instruction with a certain time sequence and strength and forwards the control instruction to the magnetic field pattern controller 20, the magnetic field pattern controller 20 generates a control signal according to the control instruction sent by the central controller 50 and sends the control signal to the magnetic field generation driver 30, and the magnetic field generation driver 30 receives the control signal generated by the magnetic field pattern controller 20 and sends a driving signal to the circular coil 11 according to the control signal so as to drive the coil to generate an induced magnetic field with a corresponding frequency and strength.
In one embodiment, the central controller 50 analyzes the tumor according to the size and position information, which includes:
step one, extracting the size and position information of a tumor in a breast tumor ultrasonic image by adopting a simple breast ultrasonic image segmentation algorithm based on a watershed algorithm;
step two, calculating the maximum section area S1 of the minimum envelope contour curve of the breast tumor and the maximum secant length L of the curve by adopting a niche algorithm based on a neighborhood area minimum strategy according to the size and the position information of the tumor1And a center position P1And maximum tangent profile curve maximum section area S2The longest secant length L of the curve2And a center position P2；
Step three, judging the tumor grade according to the length of the longest secant of the maximum envelope contour curve, wherein the optimal judgment principle is as follows: small size tumor L2<2cm, large-sized tumor 2<L2<5cm diffuse tumor L2>5cm；
Step four, selecting a mode of the therapeutic magnetic field according to the grade of the tumor, wherein the optimal principle of the therapeutic magnetic field is as follows: the first preferred principle-the small magnetic field stimulation principle, the large-size breast tumor prefers the therapeutic magnetic field mode with low frequency and low magnetic field strength; the 2 nd optimal selection principle-the therapeutic contour is from large to small, the therapeutic magnetic field is from small to large, each optimal therapeutic course is divided into three stages, the first stage-the pre-stimulation stage, the therapeutic coil is optimal selection of a multi-coil same stimulation mode, same magnetic field frequency and same stimulation magnetic field intensity, a plurality of coils synchronously stimulate the stimulation magnetic field, and the coil stimulation magnetic field covers the maximum section area S of the minimum envelope contour curve1The stimulating magnetic field is preferably at a lower frequency,a magnetic field stimulation mode with lower magnetic field intensity, wherein the stimulation time is preferably 30 minutes or more; second stage-enhanced stimulation stage, the therapeutic coil preferably has multiple independent coil stimulation modes, the stimulation coils have different magnetic field frequencies and different stimulation magnetic field strengths, the magnetic fields of the multiple coils do not require synchronous excitation, and the stimulation magnetic field of the coil covers the maximum cross-sectional area S of the maximum envelope profile curve2The stimulation magnetic field is preferably in a higher frequency and higher magnetic field intensity magnetic field stimulation mode, and the stimulation time is preferably 20 minutes or more; the third stage, repairing stimulation stage, is that the treating coil preferably has multiple coils in the same stimulation mode, the same magnetic field frequency and the same stimulation magnetic field strength, and the multiple coils synchronously excite the stimulation magnetic field to cover the maximum section area S of the minimum envelope contour curve1The stimulation magnetic field is preferably lower in frequency (preferably not higher or lower than the stimulation frequency selected in the first stage), lower in magnetic field intensity and stimulation mode (preferably not higher or lower than the stimulation intensity selected in the first stage), and preferably for 40 minutes or more;
step five, according to the maximum section area S of the minimum envelope contour curve1The longest secant length L of the curve1And a center position P1Preferably, the size and configuration of the stimulation coil, and the preferred coil principles are: first preference principle-according to the tumor size principle, small-size tumors prefer single-coil stimulation and dual-coil stimulation (dual-coil prefers a combined mode in which two non-adjacent coils work together); the large-size tumor is preferably stimulated by double coils or four coils (the double coils are preferably combined modes in which two non-adjacent coils work together); four coils are preferably selected for stimulating the dispersive tumor; in the second preferred principle, the step-by-step enhancement principle, the number of stimulation coils is preferably increased in the enhanced stimulation stage compared with the pre-stimulation stage and the enhanced stimulation stage in the repair stimulation stage in three different treatment stages of each treatment process.
Furthermore, the central controller monitors the whole portable high-frequency magnetic energy breast cancer auxiliary therapeutic apparatus, the display module is configured to display running state information of the system, and the mobile control front end is used for carrying out portable control on the portable high-frequency magnetic energy breast cancer auxiliary therapeutic apparatus through Bluetooth or Wi-Fi.
In one embodiment, the magnetic field generating coil set 10 of the magnetic breast cancer therapeutic aid comprises 4 circular coils 11, and the coil center points of the 4 circular coils 11 are respectively located at four vertexes of a square.
In a specific embodiment, the magnetic energy breast cancer assistant therapeutic apparatus is provided with 4 circular coils 11 in a cup corresponding to a breast where a tumor is located, wherein the 1 st coil, the 2 nd coil, the 3 rd coil and the 4 th coil are fixed in an oriented mode around the tumor position, each pair of magnetic coils are not parallel to each other, each of the 1 st coil, the 2 nd coil, the 3 rd coil and the 4 th coil is positioned in the cup to be close to the edges of four shells, each circular coil is provided with a separate sealing shell, the four coils are embedded in a fixed shell, and the fixed shell is a circular shell and is made into an underwear cup form. The 1 st coil, the 2 nd coil, the 3 rd coil and the 4 th coil are uniformly arranged in a surrounding mode, meanwhile, in order to enable a synthetic magnetic field formed by superposition to form a local maximum value at a cancerous tumor, angle adjustment can be carried out on 4 circular coils, each circular coil is located in 4 different planes, the effective diameter of each single coil is 60mm, the size of a wound copper wire of each coil is 3 mm square, and the number of turns is 5-10.
It can be understood that the magnetic field generating coil assembly 10 is disposed around the breast with tumor, and precisely generates modulated alternating magnetic field in the tumor region, so as to induce focused alternating induction electric field in the tumor region, and the alternating induction electric field can interfere and interrupt mitosis of tumor cells to induce cancer cells to die due to abnormal division, and can also open ion permeation channels of tumor cells, so as to improve administration efficiency of tumor and chemotherapy drugs to tumor cells, improve drug effect of drugs for treating tumor and cancer, and generate no side effect on normal tissue cells.
In a specific embodiment, the 1 st coil, the 2 nd coil, the 3 rd coil and the 4 th coil can independently generate a 1 st therapeutic magnetic field with the frequency of 150-. As shown in fig. 4, the magnetic field pattern controller is capable of timing control, intensity control, and frequency control to produce a particular drive pattern for a single coil or multiple coils. The magnetic field generation driver generates specific driving currents for a single coil or a plurality of coils according to a specific driving mode set by the magnetic field mode controller, so that the driving coils generate therapeutic magnetic fields with specific frequency and strength.
In one embodiment, the effective diameter of the circular coil 11 is 50-70mm, the number of turns is 4-10 turns, and the circular coil 11 is formed by winding copper wires with the size of 2-4 square millimeters.
It can be understood that, the magnetic field generating coil assembly 10 can be fixed on the bra by selecting a suitable position according to the tumor information as a reference after the chest is subjected to ultrasonic scanning by the ultrasonic positioner 40, the magnetic field generating coil assembly 10 is arranged around the breast with the tumor, and a modulated alternating magnetic field is precisely generated in the tumor area, so that a focused alternating induction electric field can be induced in the tumor area, the alternating induction electric field can interfere and interrupt mitosis of the tumor cells to cause the cancer cells to die due to the abnormal division, and an ion permeation channel of the tumor cells can be opened, so that the administration efficiency of the tumor and the chemotherapeutic drugs to the tumor cells can be improved, the drug effect of the drugs for treating the tumor and the cancer can be improved, and no side effect is generated on normal tissue cells.
In the embodiment of the invention, the mitosis of cells is disturbed and interrupted by using the medium-frequency alternating magnetic field, so that the tumor and cancer tissue cells can be effectively killed, and no side effect is caused on normal tissue cells; the permeability of an ion transmission channel which can effectively excite tumor and cancer histiocyte is accurately designed and excited by the alternating magnetic field, the administration targeting accuracy and efficiency of the chemotherapeutic drug can be effectively improved, the administration amount of the chemotherapeutic drug is reduced, and the whole treatment effect is improved while the dosage of the chemotherapeutic drug is reduced. The magnetic field generating coil group 10 of the magnetic breast cancer auxiliary therapeutic apparatus is fixedly arranged in the bra, so that the portable and wearable design is realized, a patient can wear the magnetic breast cancer auxiliary therapeutic apparatus for use, and the usability of the magnetic breast cancer auxiliary therapeutic apparatus is greatly improved.
In one embodiment, as shown in fig. 5, the main driving circuit of the magnetic field mode controller of the portable high-frequency magnetic energy breast cancer therapeutic apparatus includes a control circuit 1, a driving circuit 2, a rectifying circuit 3, a magnetic field generating main circuit 4 and a coil adapter 5. The control circuit 1 preferably selects an integrated circuit SG3525 as a push-pull control circuit, the drive circuit 2 is a push-pull drive circuit consisting of a plurality of triodes or field effect transistors, the rectification circuit 3 is a high-voltage transformer isolation and high-voltage rectification circuit, the isolation transformer provides second-stage reinforced insulation of equipment, and the magnetic field generation main circuit 4 is a magnetic field generation main circuit consisting of a high-voltage energy storage capacitor, a coil adapter 5 and a silicon controlled rectifier.
The application method of the magnetic energy breast cancer auxiliary therapeutic apparatus provided by the embodiment of the invention comprises the following steps: the magnetic field mode controller 20 acquires a control instruction of a preset time sequence and intensity to generate a control signal; the magnetic field generation driver 30 receives the control signal generated by the magnetic field pattern controller 20 and transmits a driving signal to the circular coil 11 according to the control signal; the circular coil 11 generates an alternating magnetic field of corresponding frequency and intensity according to the driving signal.
The magnetic field mode controller 20 is externally provided with a plurality of mode control buttons for the user to adjust the magnetic field, including a frequency selection button, a waveform selection button, an intensity adjustment button, a switch button, and the like. The switching of the frequency selection key, the waveform selection key and the intensity adjustment key all enables control signals under preset control instructions of different time sequences and intensities to be sent to the magnetic field generation driver 30, the magnetic field generation driver 30 generates corresponding driving signals according to the control signals, and the driving coils generate induction magnetic fields with corresponding frequencies and intensities. The magnetic field generating driver 30 receives the control signal generated by the magnetic field pattern controller 20, and generates a driving current signal for each coil at a specific timing based on the control signal, so as to drive the circular coil 11 of the magnetic field generating coil assembly 10 to generate an induced magnetic field at a specific frequency and strength. The magnetic field mode controller can respectively realize that each single circular coil generates induction magnetic fields with different frequencies and intensities.
Further, still include: the ultrasonic positioner 40 performs ultrasonic scanning on the chest to obtain tumor information, and provides guidance for positioning and mounting the magnetic field generating coil assembly 10.
Further, still include: the central controller 50 acquires tumor information and generates control instruction information according to the tumor information; the control instruction information includes control instructions of a particular timing and strength.
In one embodiment, the ultrasound positioner 40 performs an ultrasound scan on the breast to obtain tumor information, and a simple watershed algorithm-based breast ultrasound image segmentation algorithm can be used to extract the size and position information of the tumor in the breast tumor ultrasound image. The central controller 50 generates control instruction information based on the tumor information. Wherein the tumor information comprises size and location information of the tumor. Specifically, the central controller 50 analyzes according to the size and position information of the tumor, matches a control instruction with a certain time sequence and strength and forwards the control instruction to the magnetic field pattern controller 20, the magnetic field pattern controller 20 generates a control signal according to the control instruction sent by the central controller 50 and sends the control signal to the magnetic field generation driver 30, and the magnetic field generation driver 30 receives the control signal generated by the magnetic field pattern controller 20 and sends a driving signal to the circular coil 11 according to the control signal so as to drive the coil to generate an induced magnetic field with a corresponding frequency and strength.
In one embodiment, the central controller 50 analyzes the tumor according to the size and position information, which includes:
step one, extracting the size and position information of a tumor in a breast tumor ultrasonic image by adopting a simple breast ultrasonic image segmentation algorithm based on a watershed algorithm;
step two, calculating the maximum section area S1 of the minimum envelope contour curve of the breast tumor and the maximum secant length L of the curve by adopting a niche algorithm based on a neighborhood area minimum strategy according to the size and the position information of the tumor1And a center position P1And maximum tangent profile curve maximum section area S2The most extreme of the curveLength of long secant line L2And a center position P2；
Step three, judging the tumor grade according to the length of the longest secant of the maximum envelope contour curve, wherein the optimal judgment principle is as follows: small size tumor L2<2cm, large-sized tumor 2<L2<5cm diffuse tumor L2>5cm；
Step four, selecting a mode of the therapeutic magnetic field according to the grade of the tumor, wherein the optimal principle of the therapeutic magnetic field is as follows: the first preferred principle-the small magnetic field stimulation principle, the large-size breast tumor prefers the therapeutic magnetic field mode with low frequency and low magnetic field strength; the 2 nd optimal selection principle-the therapeutic contour is from large to small, the therapeutic magnetic field is from small to large, each optimal therapeutic course is divided into three stages, the first stage-the pre-stimulation stage, the therapeutic coil is optimal selection of a multi-coil same stimulation mode, same magnetic field frequency and same stimulation magnetic field intensity, a plurality of coils synchronously stimulate the stimulation magnetic field, and the coil stimulation magnetic field covers the maximum section area S of the minimum envelope contour curve1The stimulating magnetic field is preferably in a lower frequency and lower magnetic field intensity magnetic field stimulating mode, and the stimulating time is preferably 30 minutes or more; second stage-enhanced stimulation stage, the therapeutic coil preferably has multiple independent coil stimulation modes, the stimulation coils have different magnetic field frequencies and different stimulation magnetic field strengths, the magnetic fields of the multiple coils do not require synchronous excitation, and the stimulation magnetic field of the coil covers the maximum cross-sectional area S of the maximum envelope profile curve2The stimulation magnetic field is preferably in a higher frequency and higher magnetic field intensity magnetic field stimulation mode, and the stimulation time is preferably 20 minutes or more; the third stage, repair stimulation stage, is to select multiple coils with the same stimulation mode, frequency and intensity, to excite the magnetic field synchronously, to cover the maximum section area S of the minimum envelope contour curve1The stimulation magnetic field is preferably lower in frequency (preferably not higher or lower than the stimulation frequency selected in the first stage), lower in magnetic field intensity and stimulation mode (preferably not higher or lower than the stimulation intensity selected in the first stage), and preferably for 40 minutes or more;
step five, according to the maximum section area S of the minimum envelope contour curve1Curve the mostLength of long secant line L1And a center position P1Preferably, the size and configuration of the stimulation coil, and the preferred coil principles are: first preference principle-according to the tumor size principle, small-size tumors prefer single-coil stimulation and dual-coil stimulation (dual-coil prefers a combined mode in which two non-adjacent coils work together); the large-size tumor is preferably stimulated by double coils or four coils (the double coils are preferably combined modes in which two non-adjacent coils work together); four coils are preferably selected for stimulating the dispersive tumor; in the second preferred principle, the step-by-step enhancement principle, the number of stimulation coils is preferably increased in the enhanced stimulation stage compared with the pre-stimulation stage and the enhanced stimulation stage in the repair stimulation stage in three different treatment stages of each treatment process.
Furthermore, the central controller monitors the whole portable high-frequency magnetic energy breast cancer auxiliary therapeutic apparatus, the display module is configured to display running state information of the system, and the mobile control front end is used for carrying out portable control on the portable high-frequency magnetic energy breast cancer auxiliary therapeutic apparatus through Bluetooth or Wi-Fi.
It can be understood that the magnetic field generating coil assembly 10 is disposed around the breast with tumor, and precisely generates modulated alternating magnetic field in the tumor region, so as to induce focused alternating induction electric field in the tumor region, and the alternating induction electric field can interfere and interrupt mitosis of tumor cells to induce cancer cells to die due to abnormal division, and can also open ion permeation channels of tumor cells, so as to improve administration efficiency of tumor and chemotherapy drugs to tumor cells, improve drug effect of drugs for treating tumor and cancer, and generate no side effect on normal tissue cells.
Referring to fig. 6, an embodiment of the invention provides a computer terminal device, which includes one or more processors and a memory. The memory is coupled to the processor and is used for storing one or more programs, and when the one or more programs are executed by the one or more processors, the one or more processors implement the use method of the magnetic energy breast cancer therapeutic aid in any one of the above embodiments.
The processor is used for controlling the overall operation of the computer terminal equipment so as to complete all or part of the steps of the using method of the magnetic energy breast cancer auxiliary therapeutic apparatus. The memory is used to store various types of data to support the operation at the computer terminal device, which data may include, for example, instructions for any application or method operating on the computer terminal device, as well as application-related data. The Memory may be implemented by any type of volatile or non-volatile Memory device or combination thereof, such as Static Random Access Memory (SRAM), Electrically Erasable Programmable Read-Only Memory (EEPROM), Erasable Programmable Read-Only Memory (EPROM), Programmable Read-Only Memory (PROM), Read-Only Memory (ROM), magnetic Memory, flash Memory, magnetic disk, or optical disk.
In an exemplary embodiment, the computer terminal Device may be implemented by one or more Application Specific Integrated Circuits (ASICs), Digital Signal Processors (DSPs), Digital Signal Processing Devices (DSPDs), Programmable Logic Devices (PLDs), Field Programmable Gate Arrays (FPGAs), controllers, microcontrollers, microprocessors or other electronic components, and is configured to perform the method for using the magnetic energy breast cancer therapeutic aid, and achieve the technical effects consistent with the above method.
In another exemplary embodiment, a computer readable storage medium is provided, which includes a computer program, when executed by a processor, for implementing the steps of the method for using the magnetic energy breast cancer therapeutic aid in any one of the above embodiments. For example, the computer readable storage medium may be the above memory including a computer program, and the computer program may be executed by a processor of a computer terminal device to implement the above method for using the magnetic breast cancer therapeutic aid, and achieve the same technical effects as the above method.
While the foregoing is directed to the preferred embodiment of the present invention, it will be understood by those skilled in the art that various changes and modifications may be made without departing from the spirit and scope of the invention.
Claims (10)
1. A magnetic energy breast cancer auxiliary therapeutic apparatus is characterized by comprising a magnetic field generating coil group, a magnetic field mode controller and a magnetic field generating driver;
the magnetic field generating coil set comprises a plurality of circular coils and is used for generating an alternating magnetic field with preset frequency and intensity; the magnetic field generating coil group is fixedly arranged in the bra;
the magnetic field mode controller is used for sending a control instruction with preset time sequence and strength to the magnetic field generation driver and generating a control signal;
the magnetic field generation driver is used for receiving the control signal generated by the magnetic field mode controller and sending a driving signal to the circular coil according to the control signal so as to drive the coil to generate an induction magnetic field with corresponding frequency and intensity.
2. The magnetic energy breast cancer auxiliary therapeutic apparatus according to claim 1, further comprising an ultrasonic positioner, wherein the ultrasonic positioner is used for performing ultrasonic scanning on the breast to obtain tumor information and providing guidance basis for positioning and installing the magnetic field generating coil set.
3. The magnetic energy breast cancer therapeutic aid of claim 2, further comprising a central controller, wherein the central controller is used for acquiring the tumor information and generating control instruction information according to the tumor information; the control instruction information includes control instructions of a particular timing and strength.
4. The magnetic energy breast cancer therapeutic aid of claim 1, wherein the magnetic field generating coil set comprises 4 circular coils, and the coil center points of the 4 circular coils are respectively located at four vertices of a square.
5. The magnetic energy breast cancer auxiliary therapeutic apparatus according to claim 1, wherein the effective diameter of the circular coil is 50-70mm, the number of turns is 4-10 turns, the circular coil is formed by winding a copper wire, and the size of the copper wire is 2-4 square millimeters.
6. A use method of a magnetic breast cancer auxiliary therapeutic apparatus is characterized by comprising the following steps:
the magnetic field mode controller acquires a control instruction of a preset time sequence and intensity and generates a control signal;
the magnetic field generation driver receives the control signal generated by the magnetic field mode controller and sends a driving signal to the circular coil according to the control signal;
the circular coil generates an alternating magnetic field with corresponding frequency and intensity according to the driving signal.
7. The use method of the magnetic energy breast cancer therapeutic aid according to claim 6, further comprising:
the ultrasonic positioner carries out ultrasonic scanning on the chest to obtain tumor information and provides a guiding basis for positioning and mounting the magnetic field generating coil group.
8. The use method of the magnetic energy breast cancer therapeutic aid according to claim 7, further comprising the following steps:
the central controller acquires the tumor information and generates control instruction information according to the tumor information; the control instruction information includes control instructions of a particular timing and strength.
9. A computer terminal device, comprising:
one or more processors;
a memory coupled to the processor for storing one or more programs;
when the one or more programs are executed by the one or more processors, the one or more processors implement the use method of the magnetic energy breast cancer therapeutic aid as claimed in any one of claims 6 to 8.
10. A computer readable storage medium, on which a computer program is stored, wherein the computer program, when being executed by a processor, implements a method for using a magnetic energy breast cancer therapeutic aid according to any one of claims 6 to 8.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210085855.3A CN114470524A (en) | 2022-01-25 | 2022-01-25 | Portable high-frequency magnetic energy breast cancer auxiliary therapeutic apparatus and use method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210085855.3A CN114470524A (en) | 2022-01-25 | 2022-01-25 | Portable high-frequency magnetic energy breast cancer auxiliary therapeutic apparatus and use method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114470524A true CN114470524A (en) | 2022-05-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210085855.3A Pending CN114470524A (en) | 2022-01-25 | 2022-01-25 | Portable high-frequency magnetic energy breast cancer auxiliary therapeutic apparatus and use method thereof |
Country Status (1)
| Country | Link |
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| CN (1) | CN114470524A (en) |
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2022
- 2022-01-25 CN CN202210085855.3A patent/CN114470524A/en active Pending
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