CN114469334A - Laser output device, method, terminal and storage medium - Google Patents
Laser output device, method, terminal and storage medium Download PDFInfo
- Publication number
- CN114469334A CN114469334A CN202110758898.9A CN202110758898A CN114469334A CN 114469334 A CN114469334 A CN 114469334A CN 202110758898 A CN202110758898 A CN 202110758898A CN 114469334 A CN114469334 A CN 114469334A
- Authority
- CN
- China
- Prior art keywords
- laser
- target
- target object
- feedback signal
- region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract description 22
- 230000001678 irradiating effect Effects 0.000 claims abstract description 19
- 230000008878 coupling Effects 0.000 claims description 27
- 238000010168 coupling process Methods 0.000 claims description 27
- 238000005859 coupling reaction Methods 0.000 claims description 27
- 238000004590 computer program Methods 0.000 claims description 22
- 238000013136 deep learning model Methods 0.000 claims description 21
- 238000012014 optical coherence tomography Methods 0.000 claims description 18
- 230000006870 function Effects 0.000 claims description 14
- 238000000608 laser ablation Methods 0.000 abstract description 32
- 238000002679 ablation Methods 0.000 abstract description 20
- 210000004204 blood vessel Anatomy 0.000 description 11
- 238000012549 training Methods 0.000 description 8
- 238000013507 mapping Methods 0.000 description 6
- 238000010586 diagram Methods 0.000 description 5
- 239000013307 optical fiber Substances 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 208000037260 Atherosclerotic Plaque Diseases 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 4
- 150000002632 lipids Chemical class 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 238000004891 communication Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000011859 microparticle Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 210000000865 mononuclear phagocyte system Anatomy 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 238000003325 tomography Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 230000002238 attenuated effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000013135 deep learning Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 125000003473 lipid group Chemical group 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0066—Optical coherence imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00345—Vascular system
- A61B2018/00404—Blood vessels other than those in or around the heart
- A61B2018/0041—Removal of thrombosis
Abstract
The application is applicable to the field of optics and provides a laser output device, a laser output method, a laser output terminal and a storage medium. Wherein, the output device of the laser comprises: an acquisition unit for acquiring a first feedback signal; the first feedback signal is obtained by irradiating a first area of a target object by using first initial laser; the laser parameter determining unit is used for determining a target laser parameter according to the first feedback signal, wherein the target laser parameter is a laser parameter of laser capable of ablating a first region of the target object; and the output unit is used for outputting the target laser corresponding to the target laser parameter. The embodiment of the application can reduce the operation complexity of an operator of the laser ablation system and improve the ablation efficiency.
Description
Technical Field
The present application relates to the field of optics, and in particular, to a laser output device, method, terminal, and storage medium.
Background
Laser ablation refers to the irradiation of atherosclerotic plaques in blood vessels with ultraviolet laser light. After being absorbed by the atherosclerotic plaque, the ultraviolet light can break the carbon-hydrogen bonds of the plaque, causing the tissue temperature to rise and creating micro-vapor bubbles at the front end of the catheter that outputs the ultraviolet laser. The expansion and collapse of these micro-vapor bubbles can disrupt the plaque within the vessel, breaking down the plaque into water, gas and small particles smaller than 10 μm. The absorption of these micro-particles by the reticuloendothelial system can avoid the blockage of blood vessels.
Currently, when laser ablation is performed on plaque, an operator is required to frequently operate the laser ablation system. The operator needs to try from the lowest laser energy through the laser ablation system to see whether ablation can be performed on the plaque, if the ablation cannot be performed on the plaque, the laser energy is increased and the trial is repeated until the energy of the laser emitted by the laser of the laser ablation system can obviously perform ablation on the plaque, and then the laser ablation operation is performed on the plaque.
Therefore, the existing laser ablation mode has low ablation efficiency.
Disclosure of Invention
The embodiment of the application provides a laser output device, a laser output method, a laser output terminal and a laser output storage medium, which can reduce the operation complexity of an operator of a laser ablation system and improve the ablation efficiency.
A first aspect of the embodiments of the present application provides an output device for laser, including:
an acquisition unit for acquiring a first feedback signal; the first feedback signal is obtained by irradiating a first area of a target object by using first initial laser;
the laser parameter determining unit is used for determining a target laser parameter according to the first feedback signal, wherein the target laser parameter is a laser parameter of laser capable of ablating a first region of the target object;
and the output unit is used for outputting the target laser corresponding to the target laser parameter.
A second aspect of the embodiments of the present application provides a method for outputting laser, including:
acquiring a first feedback signal; the first feedback signal is obtained by irradiating a first area of a target object by using first initial laser;
determining a target laser parameter according to the first feedback signal, wherein the target laser parameter is a laser parameter of laser capable of ablating a first region of the target object;
and outputting the target laser corresponding to the target laser parameter.
A third aspect of the embodiments of the present application provides a terminal, including a memory, a processor, and a computer program stored in the memory and executable on the processor, where the processor implements functions of the above apparatus when executing the computer program.
A fourth aspect of the embodiments of the present application provides a computer-readable storage medium, which stores a computer program, and when the computer program is executed by a processor, the computer program implements the functions of the above-mentioned apparatus.
A fifth aspect of embodiments of the present application provides a computer program product, which when run on a terminal, enables the terminal to implement functions of an apparatus when executed.
In the embodiment of the application, a first feedback signal for feeding back the first initial laser by the target object is obtained, the target laser parameter of the laser capable of ablating the first area of the target object is determined according to the first feedback signal, and then the target laser corresponding to the target laser parameter is output, so that an operator does not need to try the lasers with different laser parameters one by one, based on the first feedback signal, the laser capable of ablating the target object can be output, the efficiency of laser ablation is improved, the efficiency of a laser ablation operation is improved, and the operation time is shortened.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the embodiments or the prior art descriptions will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without inventive exercise.
Fig. 1 is a schematic structural diagram of an output device of laser according to an embodiment of the present disclosure;
fig. 2 is a schematic diagram of a first structure of a terminal provided in an embodiment of the present application;
fig. 3 is a schematic flow chart of an implementation of a laser output method provided in an embodiment of the present application;
fig. 4 is a second structural diagram of a terminal according to an embodiment of the present application.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present application is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present application without making any creative effort, shall be protected by the present application.
Laser ablation refers to the irradiation of atherosclerotic plaques in blood vessels with ultraviolet laser light. After being absorbed by the atherosclerotic plaque, the ultraviolet light can break the carbon-hydrogen bonds of the plaque, causing the tissue temperature to rise and creating micro-vapor bubbles at the front end of the catheter that outputs the ultraviolet laser. The expansion and collapse of these micro-vapor bubbles can disrupt the plaque within the vessel, breaking down the plaque into water, gas and small particles smaller than 10 μm. The absorption of these micro-particles by the reticuloendothelial system can avoid the blockage of blood vessels.
Currently, when laser ablation is performed on plaque, an operator is required to frequently operate the laser ablation system. The operator needs to try from the lowest laser energy through the laser ablation system to see whether ablation can be performed on the plaque, if the ablation cannot be performed on the plaque, the laser energy is increased and the trial is repeated until the energy of the laser emitted by the laser of the laser ablation system can obviously perform ablation on the plaque, and then the laser ablation operation is performed on the plaque.
Therefore, the existing laser ablation mode has low ablation efficiency. Meanwhile, since the finally selected laser energy is related to the experience of the operator, if the experience of the operator is insufficient, the finally achieved ablation effect is also poor, and thus the reliability of the laser ablation mode is also low.
In order to explain the technical means of the present application, the following description will be given by way of specific examples.
Fig. 1 is a schematic structural diagram of a laser output device 100 according to an embodiment of the present disclosure, where the laser output device 100 is configured on a terminal, and is suitable for a situation that an operator of a laser ablation system needs to reduce operation complexity and improve ablation efficiency. Wherein, the terminal can be a laser ablation system.
Specifically, the output device 100 of the laser may include an acquisition unit 101, a laser parameter determination unit 102, and an output unit 103.
The obtaining unit 101 may be configured to obtain a first feedback signal.
The first feedback signal is obtained by irradiating a first area of the target object with the first initial laser.
In some embodiments of the present application, the target object may refer to an object requiring ablation, for example, the target object may be a blood vessel, and the first region of the target object may be a first region in the blood vessel.
The first initial laser is a laser applied to a first region of the target object. Wherein, the first initial laser can be selected according to actual conditions.
In some embodiments of the present application, the first initiation laser may be an ultraviolet laser of any energy emitted by a laser of the terminal, for example, the ultraviolet laser with the lowest energy. In other embodiments of the present application, the first initial laser may also be near infrared light emitted by a quasi-continuous near infrared laser light source.
The first feedback signal is a feedback signal formed by reflecting reflected light of the target object back through the conduit after the target object generates absorption, reflection and other reactions on the first initial laser after the first initial laser irradiates the first region of the target object, and the feedback signal can be used for acquiring tissue composition information of the target object.
In some embodiments of the present application, the first feedback signal may include an Optical Coherence Tomography (OCT) signal obtained by irradiating the first region of the target object with the first initial laser, an Index of Plane Attenuation (IPA) signal, or other signals obtained by feeding back the first initial laser by the target object.
The optical coherence tomography signal mainly reflects the tomography structure of the target object, and the tomography structure of the target object is analyzed after the interference of the reflected light from the target object and the reference light is collected, so that the target types of different target objects are reflected. The plaque attenuation index reflects the type of target to which different target objects belong, primarily by collecting the absorption attenuated light from the target object.
Specifically, the first feedback signal may be obtained through a catheter. In some embodiments of the present application, the catheter may comprise a fiber optic bundle and an optical fiber for feedback. In other embodiments of the present application, the catheter may further include a large-core optical fiber and an optical fiber for feedback. The structure of the duct is not limited herein.
The manner of acquiring the first feedback signal may be selected according to actual conditions. In some embodiments of the present application, the terminal may emit a first initial laser to a first region of the target object, and collect a first feedback signal for feeding back the first initial laser by the first region of the target object.
For example, the terminal may be provided with a near infrared laser light source having a separate light coupling port. The terminal transmits first initial laser to a target object through a near-infrared laser light source, and collects a first feedback signal for feeding back the first initial laser by the target object.
And a laser parameter determining unit 102, configured to determine a target laser parameter according to the first feedback signal.
Wherein the target laser parameter is a laser parameter of a laser capable of ablating a first region of a target object.
Specifically, in some embodiments of the present application, the laser parameter determining unit 102 may be specifically configured to: determining a target type of the target object according to the first feedback signal; and determining target laser parameters according to the target type of the target object.
Wherein the target type may refer to a composition of the target object. Specifically, taking the above-described target object as a plaque to be laser-ablated as an example, the target type of the target object may include a fibrous plaque, a lipid plaque, and the like.
In some embodiments of the present application, the terminal may store a mapping relationship between the first feedback signal and the target type in a memory, and based on the mapping relationship, the terminal may determine the target type of the target object according to the first feedback signal.
In some embodiments of the present application, the first feedback signal may include an optical coherence tomography signal obtained by irradiating a first region of the target object with the first initial laser light.
At this time, the laser parameter determination unit 102 is further configured to: and inputting the optical coherence tomography signal into a pre-trained deep learning model, and acquiring a target type output by the deep learning model.
In some embodiments of the present application, the deep learning model may be a Mask-rcnn (regions with CNN features) target detection model or other deep learning-based feature detection models.
In some embodiments of the present application, a converged deep learning model may be trained based on a sample feedback signal for feeding back a first initial laser or a sample laser that is the same as the first initial laser to target objects of different target types, and the trained deep learning model may be used to distinguish and identify specific information of various target objects, so as to output the target type of the target object according to the input first feedback signal.
Specifically, the laser output apparatus 100 may further include a training unit, configured to obtain a training set, where the training set includes multiple sample optical coherence tomography signals and a sample target type corresponding to each sample optical coherence tomography signal; inputting the training set into a deep learning model to be trained for processing, and calculating the accuracy of the deep learning model to be trained according to the target type output by the deep learning model to be trained and the sample target type; and if the accuracy of the deep learning model to be trained is smaller than the preset accuracy threshold, adjusting parameters in the deep learning model to be trained, and acquiring the training set again for training until the accuracy of the deep learning model to be trained is larger than or equal to the preset accuracy threshold, so as to obtain the trained deep learning model.
In other embodiments of the present application, the laser parameter determining unit 102 may be further configured to: calculating a plaque attenuation index corresponding to the target object according to the optical coherence tomography signal; and determining the target type of the target object according to the plaque attenuation index. In particular, the plaque decay index corresponding to the target object
Wherein, mutIs the value of the light attenuation coefficient in the maximum vector of the light attenuation coefficient,
represents μtNumber of pixels, N, greater than a given threshold value x of light attenuation coefficienttotalThe total number of pixels representing the active area, N in some embodiments of the present applicationtotalMay have a value of 500.
In some embodiments of the present application, the target type of the target object may be determined according to the plaque attenuation index and a pre-stored mapping relationship between the plaque attenuation index and the target type.
In some embodiments of the present application, if the plaque decay index is within a preset decay index threshold range, the target type of the target object is determined as a lipid plaque.
Specifically, the light attenuation coefficient threshold value x may be set to 9.5. When x is 9.5, the sensitivity to a target object whose target type is a lipid plaque is the highest. If IPA9.5If it is greater than 100, it can be confirmed that the target type of the target object is a lipid plaque.
In other embodiments of the present application, the plaque decay index may also be input into a pre-trained deep learning model, and a target type output by the deep learning model may be obtained.
After determining the target type of the target object, the laser parameter determination unit 102 may be further configured to determine the target laser parameter according to the target type of the target object.
In the embodiment of the application, when different types of target objects are ablated, lasers with different laser parameters need to be applied to the target objects, so that a better ablation effect can be achieved correspondingly.
Specifically, in some embodiments of the present application, the target type of the target object may be determined according to the target type of the target object and a pre-stored mapping relationship between the target type and the target laser parameter. The mapping relation between the target types and the target laser parameters is used for expressing the relation between each target type and the target laser parameters capable of ablating the target object of the corresponding target type.
An output unit 103 for outputting the target laser corresponding to the target laser parameter.
Specifically, the terminal may include an electro-optical modulator, and the electro-optical modulator is used to adjust laser parameters such as laser energy of the output target laser of the laser.
In the embodiment of the application, a first feedback signal for feeding back the first initial laser by the target object is obtained, the target laser parameter of the laser capable of ablating the first area of the target object is determined according to the first feedback signal, and then the target laser corresponding to the target laser parameter is output, so that an operator does not need to try the lasers with different laser parameters one by one, based on the first feedback signal, the laser capable of ablating the target object can be output, the efficiency of laser ablation is improved, the efficiency of a laser ablation operation is improved, and the operation time is shortened.
Meanwhile, the mapping relation obtained based on a large amount of data can enable the target laser parameters output by the terminal according to the first feedback information to be more accurate, and therefore the laser ablation effect is better.
For example, in some embodiments of the present application, the target laser parameter may be laser energy. The terminal may determine laser energy capable of ablating the target object according to a first feedback signal for feeding back the first initial laser in the first region of the target object, so as to output the target laser having the same energy as the laser energy capable of ablating the target object.
In some embodiments of the present application, the terminal may be a laser ablation system that integrates a first laser 20, a laser coupling system 21, a catheter coupling device 22, and a feedback system 23, as shown in fig. 2.
Wherein, the feedback system 23 is used for executing the functions of the acquisition unit 101 and the laser parameter determination unit 102; the first laser 20, the laser coupling system 21 and the catheter coupling device 23 are used to perform the function of the output unit 103. Specifically, the feedback system 23 may include a second laser, an interference light path module, and an acquisition module, where the second laser is configured to output a first initial laser to a first region of the target object; the interference light path module is used for splitting the first initial laser to obtain reference light and sample light, and the acquisition module is used for acquiring reflected light of the first area of the target object to the sample light to obtain a first feedback signal.
In some embodiments of the present application, the feedback system 23 further includes a main controller, which is capable of controlling the second laser to output the first initial laser to the first area of the target object, determining a target laser parameter such as laser energy according to a feedback signal obtained by irradiating the first area of the target object with the first initial laser, and then outputting the target laser parameter to the first laser 20.
Alternatively, the laser coupling system 21 may comprise the first laser 20, in which case the laser coupling system 21 is configured to output the first initial laser light to the first region of the target object.
Alternatively, the laser coupling system 21, the first laser 20 and the feedback system 23 may be integrated together to form an integrated module, and at this time, the steps of the embodiment of the present application are performed by the integrated module. The first laser 20 may output the target laser according to the target laser parameter input by the feedback system 23. In some embodiments of the present application, the first laser 20 may be a semiconductor pump laser, the single pulse energy may be more than 50mJ, the pulse width is 8.5ns, the repetition frequency is 40Hz, the spot diameter is 9mm, and the output target laser does not contain stray light of 1064nm and 532 nm.
The laser coupling system 21 can focus the target laser light output by the first laser 20 into a spot that can be coupled into the conduit coupling device 22 through a lens combination, and reduce the laser spatial coherence to prevent the laser light from interfering and diffracting in the conduit coupling device 22.
The conduit coupling device 22 may be of any configuration compatible with the coupling module. For example, the eccentric single large core fiber conduit structure may also be a fiber bundle conduit structure, and is not limited herein. The catheter coupling device 22 needs to arrange the spliced optical fibers of the feedback system 23 in two catheter structures, and acquire a first feedback signal such as IPA or OCT through the spliced optical fibers. The catheter coupling device 22 may receive the target laser light output by the laser coupling system 21 and output the target laser light onto the target object.
In view of the fact that in an actual laser ablation process, if a terminal irradiates a target laser on a blood vessel wall through a catheter, the blood vessel wall may be damaged, and in order to ensure reliability of laser ablation, in some embodiments of the present application, the output device 100 of the laser further includes a determining unit, which may be configured to determine whether a first region of a target object includes an object to be ablated according to a first feedback signal.
The non-ablation object may be an object that does not need laser ablation or an object that is not capable of laser ablation, and may include a blood vessel wall, for example.
In some embodiments of the present application, the target object may include a blood vessel wall, and when the first region of the target object is irradiated with the first initial laser light, the first feedback signal may include a feedback signal that the blood vessel wall is also obtained by the first initial laser light. Therefore, the determining unit of the laser output device 100 can be used to determine whether the first region of the target object contains a non-ablation object according to the first feedback signal.
In particular, in some embodiments of the present application, while training the deep learning model, corresponding samples containing non-ablative objects may also be used for training. After an optical coherence tomography signal obtained by irradiating the first region of the target object with the first initial laser is input into a pre-trained deep learning model, the deep learning model can also detect whether the first region of the target object contains non-to-be-ablated objects.
In other embodiments of the present application, the plaque attenuation index may also be calculated from the optical coherence tomography signal. Specifically, the light attenuation coefficient threshold value x may be set to 9.5. If IPA9.5Less than 100, lipid plaques may be considered absent. If IPA9.5Close to 0, it can be confirmed that a vessel wall is present, i.e. the first region of the target object contains objects not to be ablated.
Correspondingly, the laser parameter determination unit 102 may be further configured to determine the target laser parameter according to the first feedback signal when the first region of the target object does not include the non-to-be-ablated object.
In some embodiments of the present application, if the first region of the target object does not include the non-to-be-ablated object, it is stated that the target laser will not act on the non-to-be-ablated object if the terminal outputs the target laser to the first region of the target object, and therefore, the terminal may determine the target laser parameter according to the first feedback signal and output the target laser to the first region of the target object.
Accordingly, in other embodiments of the present application, the obtaining unit 101 may further be configured to: a second feedback signal is acquired when the first region of the target object contains a non-to-be-ablated object.
In some embodiments of the present application, if the first region of the target object contains a non-ablation object, it indicates that if the terminal outputs the target laser to the first region of the target object, the target laser will act on the non-ablation object, and therefore, the terminal may obtain the second feedback signal.
The second feedback signal is obtained by irradiating a second region of the target object with a second initial laser beam. The second region is a region different from the first region of the target object. The second initial laser can be adjusted according to actual conditions. Generally, the second initial laser may be the same laser as the first initial laser. That is, the same initial laser light may be output in different regions by the same output device.
That is, the output position of the laser light may be adjusted, and the second feedback signal obtained by irradiating the second region of the target object with the second initial laser light may be acquired again. According to the obtained second feedback signal, the terminal can judge whether the second region of the target object contains the non-to-be-ablated object or not according to the second feedback signal; if the second region of the target object does not contain the non-to-be-ablated object, the target laser parameters can be determined according to the second feedback signal and the target laser is output, otherwise, the output position of the laser is continuously adjusted, and the like, so that the target laser is prevented from acting on the non-ablated object, and the reliability of laser ablation is improved.
In some embodiments of the present application, the terminal may output a first initial laser based on the feedback system 23, where the first initial laser acts on a first region of the target object through the conduit coupling device 22, and collects a first feedback signal through the conduit coupling device 22; then, the feedback system 23 determines a target laser parameter according to the collected first feedback signal, and feeds the target laser parameter back to the first laser 20, so that the first laser 20 outputs a target laser corresponding to the target laser parameter; the target laser acts on a first area of the target object through the laser coupling system 21 and the catheter coupling device 21, and laser ablation is achieved.
It should be noted that, for simplicity of description, the aforementioned embodiments of the apparatus are all described as a series of acts or combinations, but those skilled in the art will recognize that the present application is not limited by the order of acts described, as some functions may be performed in other orders according to the present application.
Fig. 3 is a schematic flow chart illustrating an implementation process of a laser output method provided by an embodiment of the present application, which can be applied to a terminal and can be applied to a situation where it is necessary to reduce the operation complexity of an operator and improve the ablation efficiency. Wherein, the terminal can be a laser ablation system.
Specifically, the output method of the laser may include the following steps S301 to S303.
Step S301, the terminal acquires a first feedback signal.
The first feedback signal is obtained by irradiating a first region of the target object with first initial laser light.
And step S302, the terminal determines target laser parameters according to the first feedback signal.
Wherein the target laser parameter is a laser parameter of a laser capable of ablating a first region of a target object.
And step S303, the terminal outputs the target laser corresponding to the target laser parameter.
In some embodiments of the present application, before determining the target laser parameter according to the first feedback signal, the terminal may include: and judging whether the first region of the target object contains a non-object to be ablated or not according to the first feedback signal.
Correspondingly, the determining, by the terminal, the target laser parameter according to the first feedback signal may include: and when the first region of the target object does not contain the non-to-be-ablated object, determining the target laser parameters according to the first feedback signal.
In some embodiments of the present application, after determining whether the first region of the target object contains a non-ablation object according to the first feedback signal, the terminal may further include: a second feedback signal is obtained.
The second feedback signal is obtained by irradiating a second region of the target object with the second initial laser, and the second region is a region different from the first region of the target object.
In some embodiments of the present application, the determining, by the terminal, the target laser parameter according to the first feedback signal may include: determining a target type of the target object according to the first feedback signal; and determining target laser parameters according to the target type of the target object.
In some embodiments of the present application, the first feedback signal may further include an optical coherence tomography signal obtained by irradiating a first region of the target object with the first initial laser light; the determining, by the terminal according to the first feedback signal, the target type of the target object may include: and inputting the optical coherence tomography signal into a pre-trained deep learning model, and acquiring the target type of the target object output by the deep learning model.
In other embodiments of the present application, the determining, by the terminal according to the first feedback signal, a target type of the target object may include: calculating a plaque attenuation index corresponding to the target object according to the optical coherence tomography signal; and determining the target type of the target object according to the plaque attenuation index.
It should be noted that, for convenience and simplicity of description, the specific implementation method of the laser output method may refer to the corresponding process of the apparatus described in fig. 1 to fig. 2, and is not described herein again.
Fig. 4 is a schematic diagram of a terminal according to an embodiment of the present application. The terminal 4 may include: a processor 40, a memory 41 and a computer program 42, such as an output program for a laser, stored in said memory 41 and executable on said processor 40. The processor 40, when executing the computer program 42, implements the functions of the modules/units in the above-described device embodiments, such as the signal acquisition unit 101, the laser parameter determination unit 102, and the output unit 103 shown in fig. 1. Alternatively, the processor 40 executes the computer program 42 to implement the steps in the above-mentioned embodiments of the output method of the laser light, such as the steps S301 to S303 shown in fig. 3.
The computer program may be divided into one or more modules/units, which are stored in the memory 41 and executed by the processor 40 to complete the application. The one or more modules/units may be a series of computer program instruction segments capable of performing specific functions, which are used to describe the execution of the computer program in the terminal.
For example, the computer program may be divided into a feedback signal acquisition unit, a laser parameter determination unit, and an output unit.
The specific functions of each unit are as follows: an acquisition unit for acquiring a first feedback signal; the first feedback signal is obtained by irradiating a first area of a target object by using first initial laser; the laser parameter determining unit is used for determining a target laser parameter according to the first feedback signal, wherein the target laser parameter is a laser parameter of laser capable of ablating a first region of the target object; and the output unit is used for outputting the target laser corresponding to the target laser parameter.
The terminal may include, but is not limited to, a processor 40, a memory 41. It will be appreciated by those skilled in the art that fig. 4 is only an example of a terminal and is not intended to be limiting and may include more or fewer components than those shown, or some components may be combined, or different components, for example, the terminal may also include input output devices, network access devices, buses, etc.
The Processor 40 may be a Central Processing Unit (CPU), other general purpose Processor, a Digital Signal Processor (DSP), an Application Specific Integrated Circuit (ASIC), an off-the-shelf Programmable Gate Array (FPGA) or other Programmable logic device, discrete Gate or transistor logic, discrete hardware components, etc. A general purpose processor may be a microprocessor or the processor may be any conventional processor or the like.
The memory 41 may be an internal storage unit of the terminal, such as a hard disk or a memory of the terminal. The memory 41 may also be an external storage device of the terminal, such as a plug-in hard disk, a Smart Media Card (SMC), a Secure Digital (SD) Card, a Flash memory Card (Flash Card), and the like provided on the terminal. Further, the memory 41 may also include both an internal storage unit and an external storage device of the terminal. The memory 41 is used for storing the computer program and other programs and data required by the terminal. The memory 41 may also be used to temporarily store data that has been output or is to be output.
It will be apparent to those skilled in the art that, for convenience and brevity of description, only the above-mentioned division of the functional units and modules is illustrated, and in practical applications, the above-mentioned function distribution may be performed by different functional units and modules according to needs, that is, the internal structure of the apparatus is divided into different functional units or modules to perform all or part of the above-mentioned functions. Each functional unit and module in the embodiments may be integrated in one processing unit, or each unit may exist alone physically, or two or more units are integrated in one unit, and the integrated unit may be implemented in a form of hardware, or in a form of software functional unit. In addition, specific names of the functional units and modules are only for convenience of distinguishing from each other, and are not used for limiting the protection scope of the present application. The specific working processes of the units and modules in the system may refer to the corresponding processes in the foregoing method embodiments, and are not described herein again.
In the above embodiments, the descriptions of the respective embodiments have respective emphasis, and reference may be made to the related descriptions of other embodiments for parts that are not described or illustrated in a certain embodiment.
Those of ordinary skill in the art will appreciate that the various illustrative elements and algorithm steps described in connection with the embodiments disclosed herein may be implemented as electronic hardware or combinations of computer software and electronic hardware. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the implementation. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present application.
In the embodiments provided in the present application, it should be understood that the disclosed apparatus/terminal and method may be implemented in other ways. For example, the above-described apparatus/terminal embodiments are merely illustrative, and for example, the division of the modules or units is only one logical division, and there may be other divisions when actually implemented, for example, a plurality of units or components may be combined or may be integrated into another system, or some features may be omitted, or not executed. In addition, the shown or discussed mutual coupling or direct coupling or communication connection may be an indirect coupling or communication connection through some interfaces, devices or units, and may be in an electrical, mechanical or other form.
The units described as separate parts may or may not be physically separate, and parts displayed as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the units can be selected according to actual needs to achieve the purpose of the solution of the embodiment.
In addition, functional units in the embodiments of the present application may be integrated into one processing unit, or each unit may exist alone physically, or two or more units are integrated into one unit. The integrated unit can be realized in a form of hardware, and can also be realized in a form of a software functional unit.
The integrated modules/units, if implemented in the form of software functional units and sold or used as separate products, may be stored in a computer readable storage medium. Based on such understanding, all or part of the flow in the method of the embodiments described above can be realized by a computer program, which can be stored in a computer-readable storage medium and can realize the steps of the embodiments of the methods described above when the computer program is executed by a processor. Wherein the computer program comprises computer program code, which may be in the form of source code, object code, an executable file or some intermediate form, etc. The computer-readable medium may include: any entity or device capable of carrying the computer program code, recording medium, usb disk, removable hard disk, magnetic disk, optical disk, computer Memory, Read-Only Memory (ROM), Random Access Memory (RAM), electrical carrier wave signals, telecommunications signals, software distribution medium, and the like. It should be noted that the computer readable medium may contain content that is subject to appropriate increase or decrease as required by legislation and patent practice in jurisdictions, for example, in some jurisdictions, computer readable media does not include electrical carrier signals and telecommunications signals as is required by legislation and patent practice.
The above-mentioned embodiments are only used for illustrating the technical solutions of the present application, and not for limiting the same; although the present application has been described in detail with reference to the foregoing embodiments, it should be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not substantially depart from the spirit and scope of the embodiments of the present application and are intended to be included within the scope of the present application.
Claims (10)
1. An output device of laser light, comprising:
an acquisition unit for acquiring a first feedback signal; the first feedback signal is obtained by irradiating a first area of a target object by using first initial laser;
the laser parameter determining unit is used for determining a target laser parameter according to the first feedback signal, wherein the target laser parameter is a laser parameter of laser capable of ablating a first region of the target object;
and the output unit is used for outputting the target laser corresponding to the target laser parameter.
2. The laser output device according to claim 1, further comprising a judging unit configured to judge whether the first region of the target object contains a non-object to be ablated, based on the first feedback signal;
correspondingly, the laser parameter determining unit is further configured to determine the target laser parameter according to the first feedback signal when the first region of the target object does not include a non-to-be-ablated object, where the non-ablated object is an object that does not need to be ablated by laser.
3. The laser output apparatus according to claim 2, wherein the obtaining unit is further configured to:
when the first region of the target object contains a non-to-be-ablated object, acquiring a second feedback signal, wherein the second feedback signal is obtained by irradiating a second region of the target object with a second initial laser, and the second region is a region different from the first region of the target object.
4. The laser output apparatus according to any one of claims 1 to 3, wherein the laser parameter determination unit is further configured to:
determining a target type of the target object according to the first feedback signal;
and determining the target laser parameters according to the target type of the target object.
5. The laser output apparatus of claim 4, wherein the first feedback signal comprises an optical coherence tomography signal obtained by irradiating a first region of the target object with the first initial laser light;
the laser parameter determination unit is further configured to:
and inputting the optical coherence tomography signal into a pre-trained deep learning model, and acquiring the target type of the target object output by the deep learning model.
6. The laser output apparatus of claim 4, wherein the first feedback signal comprises an optical coherence tomography signal obtained by irradiating a first region of the target object with the first initial laser light;
the laser parameter determination unit is further configured to:
calculating a plaque attenuation index corresponding to the target object according to the optical coherence tomography signal;
and determining the target type of the target object according to the plaque attenuation index.
7. A method of outputting laser light, comprising:
acquiring a first feedback signal; the first feedback signal is obtained by irradiating a first area of a target object by using first initial laser;
determining a target laser parameter according to the first feedback signal, wherein the target laser parameter is a laser parameter of laser capable of ablating a first region of the target object;
and outputting the target laser corresponding to the target laser parameter.
8. A terminal comprising a memory, a processor and a computer program stored in the memory and executable on the processor, characterized in that the processor implements the functionality of the apparatus according to any of claims 1 to 6 when executing the computer program.
9. The terminal of claim 8 integrated with a first laser, a laser coupling system, a conduit coupling device, and a feedback system;
wherein the feedback system is configured to perform the functions of the acquisition unit, the laser parameter determination unit, and the like of any one of claims 1 to 6;
the first laser, the laser coupling system and the catheter coupling device are used to perform the function of the output unit as claimed in any of claims 1 to 6.
10. A computer-readable storage medium, in which a computer program is stored which, when being executed by a processor, carries out the functions of an apparatus according to any one of claims 1 to 6.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110758898.9A CN114469334A (en) | 2021-07-05 | 2021-07-05 | Laser output device, method, terminal and storage medium |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110758898.9A CN114469334A (en) | 2021-07-05 | 2021-07-05 | Laser output device, method, terminal and storage medium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114469334A true CN114469334A (en) | 2022-05-13 |
Family
ID=81491530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110758898.9A Pending CN114469334A (en) | 2021-07-05 | 2021-07-05 | Laser output device, method, terminal and storage medium |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114469334A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050251116A1 (en) * | 2004-05-05 | 2005-11-10 | Minnow Medical, Llc | Imaging and eccentric atherosclerotic material laser remodeling and/or ablation catheter |
| CN109875680A (en) * | 2019-02-18 | 2019-06-14 | 清华大学 | Total optical path intelligent optical diagnosis and therapy system based on optical-coherence tomography |
| US20210038300A1 (en) * | 2019-08-05 | 2021-02-11 | Gyrus Acmi, Inc. D/B/A Olympus Surgical Technologies America | Target identification with optical feedback signal splitter |
| CN112842522A (en) * | 2021-01-27 | 2021-05-28 | 北京航空航天大学 | Intravascular optical coherence tomography laser ablation catheter |
| CN113040903A (en) * | 2021-03-23 | 2021-06-29 | 哈尔滨医科大学 | Laser ablation system |
-
2021
- 2021-07-05 CN CN202110758898.9A patent/CN114469334A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050251116A1 (en) * | 2004-05-05 | 2005-11-10 | Minnow Medical, Llc | Imaging and eccentric atherosclerotic material laser remodeling and/or ablation catheter |
| CN109875680A (en) * | 2019-02-18 | 2019-06-14 | 清华大学 | Total optical path intelligent optical diagnosis and therapy system based on optical-coherence tomography |
| US20210038300A1 (en) * | 2019-08-05 | 2021-02-11 | Gyrus Acmi, Inc. D/B/A Olympus Surgical Technologies America | Target identification with optical feedback signal splitter |
| CN112842522A (en) * | 2021-01-27 | 2021-05-28 | 北京航空航天大学 | Intravascular optical coherence tomography laser ablation catheter |
| CN113040903A (en) * | 2021-03-23 | 2021-06-29 | 哈尔滨医科大学 | Laser ablation system |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10772490B2 (en) | Monitoring device and method of operating the same | |
| CN102622569B (en) | There is the enhanced bar code reader of rim detection | |
| EP2050411B1 (en) | Light irradiation apparatus | |
| US11672425B2 (en) | Stand-alone apparatus and methods for in vivo detection of tissue malignancy using laser spectroscopy | |
| JP5647942B2 (en) | Photoacoustic imaging apparatus, probe unit used therefor, and endoscope | |
| US20160356746A1 (en) | Imaging through scattering media with high signal to noise ratio and resolution | |
| JP5469113B2 (en) | Probe unit for photoacoustic analysis and photoacoustic analyzer | |
| JP2012228401A (en) | Photoacoustic imaging apparatus, probe unit used in the same, and endoscope | |
| US20160157831A1 (en) | Apparatus and method for supporting computer-aided diagnosis | |
| EP2638850B1 (en) | Subject information obtaining device, subject information obtaining method, and program | |
| CN101518440A (en) | Biological observation apparatus and method | |
| CN103620380B (en) | There is the hair treatment apparatus of light base hair detection device | |
| GB2482867A (en) | Optimising the focus of a fibre laser | |
| RU2602718C2 (en) | Device for obtaining information on individual and method of obtaining information on individual | |
| CN114469334A (en) | Laser output device, method, terminal and storage medium | |
| US8934090B2 (en) | Evaluation of optical fiber integrity | |
| CN114668369A (en) | Diagnosis and treatment integrated probe and diagnosis and treatment system | |
| CN111077085B (en) | Wavefront-free detector self-adaptive point scanning imaging method based on deep learning | |
| US20230181044A1 (en) | Photoacoustic imaging system, and laser energy correction method and prompting method therefor | |
| RU2522965C2 (en) | Material processing device and method for operation of this device | |
| US20170265750A1 (en) | Information processing system and display control method | |
| CN109543541B (en) | Living body detection method and device | |
| CN113331788B (en) | MFMT-XCT dual-mode system | |
| CN111596307A (en) | Laser detection method and device | |
| CN110022754A (en) | The visualization system and method for optical coherence tomography for optimization |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20220609 Address after: 518000 6th floor, gaoxinxin science and technology building, 67 District, Xingdong community, Xin'an street, Bao'an District, Shenzhen City, Guangdong Province Applicant after: Shenzhen Zhongke Rongguang Medical Technology Co.,Ltd. Address before: 518055 Workshop 201-2, No. 1, Xili Liuxiandong Industrial Zone, Nanshan District, Shenzhen City, Guangdong Province Applicant before: SHENZHEN VIVOLIGHT MEDICAL DEVICE & TECHNOLOGY Co.,Ltd. |