CN114456930A - Medical care product protection effect detection device based on phage filtering effect - Google Patents

Medical care product protection effect detection device based on phage filtering effect Download PDF

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Publication number
CN114456930A
CN114456930A CN202111608229.XA CN202111608229A CN114456930A CN 114456930 A CN114456930 A CN 114456930A CN 202111608229 A CN202111608229 A CN 202111608229A CN 114456930 A CN114456930 A CN 114456930A
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China
Prior art keywords
main body
phage
culture
groove
detection device
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Pending
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CN202111608229.XA
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Chinese (zh)
Inventor
周丽
陈明
李挥
冯毅
张发勇
付钊
毕华
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Hebei Institute for Drug and Medical Device Control
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Hebei Institute for Drug and Medical Device Control
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Priority to CN202111608229.XA priority Critical patent/CN114456930A/en
Publication of CN114456930A publication Critical patent/CN114456930A/en
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/46—Means for fastening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/24—Heat exchange systems, e.g. heat jackets or outer envelopes inside the vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses a medical care product protection effect detection device based on a phage filtering effect, which comprises a main body mechanism and an auxiliary mechanism, wherein the main body mechanism comprises a main body shell, a culture bin arranged in the middle of the main body shell, a water tank arranged at the bottom of the culture bin, a partition plate arranged in the middle of the culture bin and a temperature control device used for controlling heat, and the auxiliary mechanism comprises a pressing frame arranged in the middle of the front surface of the main body shell and a sliding groove used for limiting the position of the pressing frame. According to the invention, four groups of culture bins are arranged, medical supplies are arranged on the openings of the culture bins to produce experimental groups, then a control group, a blank group and a group of experimental groups in different environments are respectively arranged, then phage are sprayed to the positions of the four groups in the same number, the culture dishes in the culture bins are taken out for a period of time for the phage counting, and the blank group and the control group are compared to obtain whether the experimental group data is qualified or not, so that the accuracy of the detection result is effectively ensured.

Description

Medical care product protection effect detection device based on phage filtering effect
Technical Field
The invention relates to the technical field of protection and detection of medical supplies, in particular to a medical supply protection effect detection device based on a phage filtering effect.
Background
At present, a plurality of diseases have infectivity, and for some diseases with stronger infectivity, medical care personnel need stronger protective articles to ensure that the medical care personnel can not be infected when in treatment, and generally used protective clothes are all protective clothes.
Protective clothing is generally all relatively monotonous, once appear damaged etc. will lose the guard action, consequently medical personnel can adopt multiple protection action stack to use, and medical supplies all need carry out a test before the in production use to guarantee that its guard action is qualified and effective, consequently need the equipment of a detection to carry out the detection of protective effect to medical supplies, propose a medical supplies protective effect detection device based on phage filter effect for this reason.
Disclosure of Invention
The present invention is directed to solving one of the technical problems of the prior art or the related art.
Therefore, the technical scheme adopted by the invention is as follows:
the utility model provides a medical supplies protective effect detection device based on phage filter effect, includes main part mechanism and complementary unit, main part mechanism includes main body cover, set up at the cultivation storehouse in main body cover middle part, set up at the water tank groove of cultivateing the storehouse bottom and set up at the baffle of cultivateing the storehouse middle part, be used for controlling thermal temperature control device, complementary unit is including setting up the pressure frame at main body cover positive middle part for the spout of frame position is pressed in the restriction.
The present invention in a preferred example may be further configured to: the middle of the main body shell is provided with a groove and a clamping groove arranged at the edge side of the groove.
Through adopting above-mentioned technical scheme for pressing fixing that the frame can be firm in the recess, will doctorse and nurses articles for use and firmly fix, avoid droing.
The present invention in a preferred example may be further configured to: the number of the culture bins is four, and two partition plates are arranged in each culture bin.
Through adopting above-mentioned technical scheme for can set up four groups experiments and go on simultaneously, thereby more accurate reacing experimental result.
The present invention in a preferred example may be further configured to: the auxiliary mechanism further comprises a control panel arranged on one side of the main body shell and a containing groove arranged in the middle of the main body shell.
Through adopting above-mentioned technical scheme for the pressure frame can be accomodate and put into the inslot, places the dust that falls, the effectual clean of guaranteeing the structure.
The present invention in a preferred example may be further configured to: the pressing frame is accommodated in the accommodating groove, and a sliding groove is formed in the side wall of the accommodating groove.
Through adopting above-mentioned technical scheme for pressing the frame can be smooth take out and use, the effectual flexibility of guaranteeing the structure and using.
By adopting the technical scheme, the invention has the beneficial effects that:
1. according to the invention, four groups of culture bins are arranged, medical supplies are arranged on the openings of the culture bins to produce experimental groups, then a control group, a blank group and a group of experimental groups in different environments are respectively arranged, then phage are sprayed to the positions of the four groups in the same number, the culture dishes in the culture bins are taken out for a period of time for the phage counting, and the blank group and the control group are compared to obtain whether the experimental group data is qualified or not, so that the accuracy of the detection result is effectively ensured.
2. According to the invention, the pressing frame is stored in the storage groove, so that the device is prevented from being shielded by the pressing frame, the storage is more convenient, the reliability of the device is effectively improved, the groove is formed in the front of the main body shell, the pressing frame can be stably clamped with the clamping groove, and the practicability of the device is improved.
Drawings
FIG. 1 is an overall schematic view of one embodiment of the present invention;
FIG. 2 is a schematic view of a chute according to one embodiment of the invention.
Reference numerals:
100. a main body mechanism; 110. a main body housing; 120. a groove; 130. a clamping groove; 140. a culture bin; 150. a water tank; 160. a partition plate; 170. a temperature control device;
200. an auxiliary mechanism; 210. a control panel; 220. a receiving groove; 230. pressing the frame; 240. a chute.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the accompanying drawings in combination with the embodiments. It should be noted that the embodiments of the present invention and features of the embodiments may be combined with each other without conflict.
It is to be understood that this description is made only by way of example and not as a limitation on the scope of the invention.
The following describes a medical care product protective effect detection device based on phage filtering effect according to some embodiments of the present invention with reference to the accompanying drawings.
The first embodiment is as follows:
referring to fig. 1-2, the medical supplies protection effect detection device based on phage filter effect provided by the present invention includes a main body mechanism 100 and an auxiliary mechanism 200, the main body mechanism 100 includes a main body housing 110, a cultivation chamber 140 opened in the middle of the main body housing 110, a water tank 150 disposed at the bottom of the cultivation chamber 140, a partition 160 disposed in the middle of the cultivation chamber 140, and a temperature control device 170 for controlling heat, the auxiliary mechanism 200 includes a pressing frame 230 disposed in the middle of the front surface of the main body housing 110, a sliding slot 240 for limiting the position of the pressing frame 230, the environment inside the cultivation chamber 140 is controlled by the water tank 150 and the temperature control device 170, so as to achieve the purpose of different controls, and the medical supplies can be firmly fixed at the opening position of the cultivation chamber 140 by the pressing frame 230, so that phage and the like can only enter the cultivation chamber 140 through the medical supplies, the experimental effect is further enhanced, and the practicability of the device is improved.
Specifically, cultivate the quantity of storehouse 140 and be four groups, and be provided with two baffles 160 in every group cultivation storehouse 140, set up different contrast experiments through four groups cultivation storehouses 140, can be accurate the experimental result that reachs to be provided with two baffles 160 in every cultivation storehouse 140, can set up the experimental result under the different positions of homogeneous environment, make the experimental result more accurate.
Example two:
as shown in fig. 1, the central portion of the main body case 110 is provided with a groove 120 and a locking groove 130 formed at the side of the groove 120, the locking position of the pressing frame 230 is limited by the groove 120, the pressing frame 230 is prevented from being inclined, and the linkage between the structures is effectively ensured.
Example three:
referring to fig. 1-2, in the above embodiment, the auxiliary mechanism 200 further includes a control panel 210 installed at one side of the main body housing 110, and a storage groove 220 formed in the middle of the main body housing 110, and the storage groove 220 is used to store the pressing frame 230, so as to prevent the pressing frame 230 from staying outside and depositing dust, which affects the detection effect of the device, and the storage can effectively save space.
Specifically, the pressing frame 230 is accommodated in the accommodating groove 220, the sliding groove 240 is formed in the side wall of the accommodating groove 220, the sliding distance of the pressing frame 230 is limited by the sliding groove 240, the pressing frame 230 can be stably clamped with the clamping groove 130, and the medical care product is effectively guaranteed to be fixed and firm.
The working principle and the using process of the invention are as follows: firstly, disinfect to cultivateing storehouse 140 inside, the medical supplies that will detect after the disinfection finishes are installed at the cultivation storehouse 140 opening part that corresponds, then will press frame 230 to follow and accomodate the inside pull out of groove 220, and rotatory make and press frame 230 to fix the position of medical supplies, starting drive keeps cultivateing the stability of storehouse 140 internal environment, and carry out the phage injection of certain time to medical supplies, still need to set up a set of contrast group in addition, a set of blank group, and the experimental group of a set of different environment, four groups altogether, open after the cultivation is accomplished and press frame 230 will place and take out the count such as carry out the phage at the inside culture dish in cultivation storehouse 140, can know whether qualified protective effect of medical supplies.
In the present invention, the term "plurality" means two or more unless explicitly defined otherwise. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items. The terms "mounted," "connected," "fixed," and the like are used broadly and should be construed to include, for example, "connected" may be a fixed connection, a detachable connection, or an integral connection; "connected" may be directly connected or indirectly connected through an intermediate. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
It will be understood that when an element is referred to as being "mounted to," "secured to" or "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like as used herein are for illustrative purposes only and do not denote a unique embodiment.
In the description herein, the description of the terms "one embodiment," "some embodiments," "specific embodiments," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (5)

1. The utility model provides a medical supplies protective effect detection device based on phage filter effect which characterized in that includes:
the main body mechanism (100) comprises a main body shell (110), a culture bin (140) arranged in the middle of the main body shell (110), a water tank (150) arranged at the bottom of the culture bin (140), a partition plate (160) arranged in the middle of the culture bin (140), and a temperature control device (170) used for controlling heat;
the auxiliary mechanism (200) comprises a pressing frame (230) arranged in the middle of the front face of the main body shell (110) and a sliding groove (240) used for limiting the position of the pressing frame (230).
2. The medical care product protective effect detection device based on the phage filter effect as claimed in claim 1, wherein the main body housing (110) is provided with a groove (120) in the middle and a clamping groove (130) at the side of the groove (120).
3. The device for detecting the protective effect of the medical supplies based on the phage filtration effect as claimed in claim 1, wherein the number of the culture chambers (140) is four, and two partition plates (160) are disposed in each culture chamber (140).
4. The device for detecting the protective effect of the medical supplies based on the phage filter effect as claimed in claim 1, wherein the auxiliary mechanism (200) further comprises a control panel (210) installed at one side of the main body housing (110), and a receiving groove (220) opened at the middle part of the main body housing (110).
5. The medical care product protective effect detection device based on the phage filter effect is characterized in that the pressing frame (230) is accommodated in the accommodating groove (220), and a sliding groove (240) is formed in the side wall of the accommodating groove (220).
CN202111608229.XA 2021-12-24 2021-12-24 Medical care product protection effect detection device based on phage filtering effect Pending CN114456930A (en)

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Application Number Priority Date Filing Date Title
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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013059946A1 (en) * 2011-10-27 2013-05-02 The Governors Of The University Of Alberta Device and method for bacterial culture and assay
JP2014079177A (en) * 2012-10-15 2014-05-08 Taihei Enviromental Science Center Co Ltd Bacterial examination device
CN206866235U (en) * 2017-07-01 2018-01-12 孙又来 A kind of breed of edible fungus servicing unit
CN210340889U (en) * 2019-06-26 2020-04-17 杭州枫霖科技有限公司 Microbial growth device based on drug sensitivity detection
CN111329164A (en) * 2020-03-17 2020-06-26 王月芳 Special epidemic situation protective clothing of new coronary pneumonia
CN112197907A (en) * 2020-09-15 2021-01-08 南京沐岗清服装有限公司 Mechanism for detecting leakproofness of medical protective clothing for microbial research after completion
CN213708329U (en) * 2020-09-29 2021-07-16 微来世界生物科技(苏州)有限公司 Microbial cultivation case for bioengineering
CN213813280U (en) * 2020-11-13 2021-07-27 广东朗固实业有限公司 Anti-pollution performance detection device for protective clothing
CN214129544U (en) * 2020-12-17 2021-09-07 瑞太干细胞中心(沈阳)有限公司 Apparatus sterilization and disinfection device for stem cell culture

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013059946A1 (en) * 2011-10-27 2013-05-02 The Governors Of The University Of Alberta Device and method for bacterial culture and assay
JP2014079177A (en) * 2012-10-15 2014-05-08 Taihei Enviromental Science Center Co Ltd Bacterial examination device
CN206866235U (en) * 2017-07-01 2018-01-12 孙又来 A kind of breed of edible fungus servicing unit
CN210340889U (en) * 2019-06-26 2020-04-17 杭州枫霖科技有限公司 Microbial growth device based on drug sensitivity detection
CN111329164A (en) * 2020-03-17 2020-06-26 王月芳 Special epidemic situation protective clothing of new coronary pneumonia
CN112197907A (en) * 2020-09-15 2021-01-08 南京沐岗清服装有限公司 Mechanism for detecting leakproofness of medical protective clothing for microbial research after completion
CN213708329U (en) * 2020-09-29 2021-07-16 微来世界生物科技(苏州)有限公司 Microbial cultivation case for bioengineering
CN213813280U (en) * 2020-11-13 2021-07-27 广东朗固实业有限公司 Anti-pollution performance detection device for protective clothing
CN214129544U (en) * 2020-12-17 2021-09-07 瑞太干细胞中心(沈阳)有限公司 Apparatus sterilization and disinfection device for stem cell culture

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