CN114450616A - Adjusting method, device, equipment and medium for film reader - Google Patents

Adjusting method, device, equipment and medium for film reader Download PDF

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Publication number
CN114450616A
CN114450616A CN201980100888.7A CN201980100888A CN114450616A CN 114450616 A CN114450616 A CN 114450616A CN 201980100888 A CN201980100888 A CN 201980100888A CN 114450616 A CN114450616 A CN 114450616A
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China
Prior art keywords
objective lens
reading platform
film reading
platform
adjustment amplitude
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Granted
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CN201980100888.7A
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CN114450616B (en
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李德云
姜斌
周浩明
邓亮
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Automatic Focus Adjustment (AREA)
  • Studio Devices (AREA)

Abstract

An adjustment method of a film reader, which can be used for adjusting the relative distance between a film reader platform (102) and an objective lens (101) in the film reader, comprises the following steps: a checking step: verifying the height of the objective lens (101) relative to the film reading platform (102) to obtain a verification result (201); an adjusting step: and controlling the relative height (202) between the initial positions of the objective lens (101) and the film reading platform (102) according to the verification result, so that the objective lens (101) can finish focusing within a preset micro-adjustment amplitude range in the focusing process. The device, the equipment and the medium can verify the relative height between the objective lens (101) and the film reading platform (102), so that whether the initial distance between the film reading platform (102) and the objective lens (101) is in a proper range or not can be quickly checked by adjusting the relative height between the objective lens (101) and the film reading platform (102) to be in a preset range, and abnormal conditions can be adjusted.

Description

Adjusting method, device, equipment and medium for film reader Technical Field
The invention relates to the technical field of electronics, in particular to a method, a device, equipment and a medium for adjusting a film reader.
Background
The slide reader is a medical device, and as shown in fig. 1, the slide reader comprises an objective lens and a slide reading platform which are oppositely arranged, wherein a slide is placed on the slide reading platform, a sample, such as a stained blood sample or a body fluid sample, is dripped on the slide, and the objective lens is connected with a camera, so that the camera can shoot the sample on the slide through the objective lens to observe the sample, and the purpose of diagnosis and the like is achieved.
In the prior art, when a film reading machine works, the distance between a film reading platform and an objective lens needs to be adjusted slightly, so that the objective lens finishes focusing to shoot a clear picture on the film reading platform; therefore, before fine adjustment, the initial movement positions of the film reading platform and the objective lens need to be verified, and if the initial position between the film reading platform and the objective lens is too far away, the fine adjustment time is long or even a focus cannot be found; if the initial position between the film reading platform and the objective lens is too close, the focus is not found in the fine adjustment process, and the film reading platform and the objective lens collide with each other.
Therefore, the problems in the prior art have yet to be solved.
Disclosure of Invention
In view of the above, in order to solve the above problems, the present invention provides the following technical solutions:
the adjustment method of the film reading machine comprises an objective lens and a film reading platform which are arranged oppositely, wherein the objective lens is used for shooting a sample on the film reading platform, and the adjustment method comprises the following steps:
a checking step: checking the height of the objective lens relative to the film reading platform to obtain a checking result;
an adjusting step: and controlling the relative height between the objective lens and the initial position of the film reading platform according to the verification result so that the objective lens can finish focusing within a preset micro-adjustment amplitude range in the focusing process.
The utility model provides a read quick-witted adjusting device of piece, read quick-witted including the relative objective that sets up and read the piece platform, objective is used for shooing read the sample on the piece platform, includes:
the verifying unit is used for verifying the height of the objective lens relative to the film reading platform to obtain a verifying result;
and the adjusting unit is used for controlling the relative height between the objective lens and the initial position of the film reading platform according to the checking result of the checking unit so that the objective lens can finish focusing within a preset micro-adjustment amplitude range in the focusing process.
Optionally, the verification unit includes:
a focusing subunit: the microscope is used for finely adjusting the relative height between the objective lens and the film reading platform so that the objective lens completes focusing;
a fine tuning subunit: the microscope is used for acquiring a first micro-adjustment amplitude for executing the relative height between the objective lens of the focusing subunit and the film reading platform;
an analysis subunit: and the first fine adjustment amplitude acquired by the fine adjustment subunit is judged whether to be within the preset fine adjustment amplitude range, so as to obtain a verification result.
Optionally, the focusing subunit is further configured to:
controlling the film reading platform to move by one step length from the initial position relative to the objective lens, wherein the length of the step length is a first preset distance;
judging whether the objective lens completes focusing;
if not, controlling the film reading platform to move by one step length relative to the objective lens until the objective lens finishes focusing.
Optionally, the focusing subunit is further configured to:
acquiring first image quality when the film reading platform is located at a first position, wherein the first image quality is image quality of a sample on the film reading platform shot by the objective lens, and the first position is a position between the initial position and the objective lens;
obtaining a second image quality when the film reading platform is located at a second position, wherein the second position and the first position are not the same;
and if the second image quality is lower than the first image quality, judging that the objective lens finishes focusing when the film reading platform is at the first position.
Optionally, the trimming subunit is further configured to:
acquiring the total step length of the movement of the film reading platform from the initial position to the position of the objective lens when the focusing is completed;
and acquiring the first fine adjustment amplitude according to the total step length, wherein the first fine adjustment amplitude is equal to the total step length multiplied by the first preset distance.
Optionally, the analysis subunit is further configured to:
if the first fine adjustment amplitude is within the preset fine adjustment amplitude range, the verification result is successful;
and if the first micro-adjustment amplitude is larger than the upper limit value of the preset micro-adjustment amplitude or smaller than the lower limit value of the preset micro-adjustment amplitude, the verification result is verification failure.
Optionally, the analysis subunit is further configured to:
the first fine adjustment amplitude is larger than a preset upper limit value of the fine adjustment amplitude, and the check result prompts that the distance between the film reading platform and the objective lens is too far;
and if the first micro-adjustment amplitude is smaller than a preset micro-adjustment amplitude lower limit value, the checking result prompts that the distance between the film reading platform and the objective lens is too close.
Optionally, the analysis subunit is further configured to:
and if the total step length of the first fine adjustment amplitude is larger than the preset maximum adjustment threshold value of the film reading platform, the objective lens still cannot finish focusing, and the verification result prompts that the distance between the film reading platform and the objective lens is too far.
Optionally, the adjusting unit is further configured to:
if the checking result indicates that the distance between the film reading platform and the objective lens is too far, adjusting the initial position to be close to the objective lens according to the first micro-adjustment amplitude;
if the checking result indicates that the distance between the film reading platform and the objective lens is too close, adjusting the initial position to be far away from the objective lens according to the first micro-adjustment amplitude;
so that the first fine adjustment amplitude is greater than the amplitude lower limit value and less than the amplitude upper limit value.
Optionally, read the piece machine and be provided with optoelectronic coupler, read and be provided with the separation blade on the piece platform, work as the separation blade shelters from when optoelectronic coupler, read the piece machine and judge read the piece platform and reach initial position, then, the adjusting unit still is used for:
and adjusting the relative position of the photoelectric coupler and the baffle plate so that the starting position is close to the objective lens.
Optionally, the adjusting unit is further configured to:
if the checking result is that the distance between the film reading platform and the objective lens is too far, adjusting the installation position of the objective lens to be close to the initial position of the film reading platform according to the first micro-adjustment range;
if the verification result is that the distance between the film reading platform and the objective lens is too close, adjusting the installation position of the objective lens to be far away from the initial position of the film reading platform according to the first micro-adjustment amplitude;
so that the first fine adjustment amplitude is greater than the amplitude lower limit value and less than the amplitude upper limit value.
Optionally, a distance between the starting position and the objective lens is greater than a preset value, so as to prevent collision during relative movement of the slide reading platform and the objective lens.
A computer device, the computer device comprising: an interaction device, an input/output (I/O) interface, a processor, and a memory having program instructions stored therein;
the interaction device is used for acquiring an operation instruction input by a user;
the processor is configured to execute program instructions stored in the memory to perform the method of any of the above.
A computer readable storage medium comprising instructions which, when executed on a computer device, cause the computer device to perform a method as claimed in any preceding claim.
The adjusting method of the film reading machine, provided by the application, can be used for adjusting the relative distance between the film reading platform and the objective lens in the film reading machine, and comprises the following steps: a checking step: checking the height of the objective lens relative to the film reading platform to obtain a checking result; an adjusting step: and controlling the relative height between the objective lens and the initial position of the film reading platform according to the verification result so that the objective lens can finish focusing within a preset micro-adjustment amplitude range in the focusing process. The embodiment of the application further provides a device, equipment and a medium, which can check the relative height between the objective lens and the image reading platform, so that the relative height between the objective lens and the image reading platform is controlled within a preset range through the adjusting step, and whether the initial distance between the image reading platform and the objective lens is within a proper range can be quickly checked, and the abnormal condition can be adjusted.
Drawings
FIG. 1 is a schematic diagram of the results of a reader;
FIG. 2 is a flowchart of an embodiment of a reader adjustment method provided by an embodiment of the present application;
fig. 3 is a flowchart of another embodiment of an adjustment method of a film reader according to an embodiment of the present application;
fig. 4A is a flowchart of another embodiment of an adjustment method of a film reader according to an embodiment of the present application;
fig. 4B is a flowchart of another embodiment of an adjustment method of a film reader according to an embodiment of the present application;
fig. 5 is a schematic view of the reading platform being too far away from the objective lens in the adjustment method of the reading machine provided in the embodiment of the present application;
fig. 6 is a schematic view of the reading platform being too close to the objective lens in the adjustment method of the reading machine according to the embodiment of the present application;
fig. 7 is a schematic view of the distance between the slide reading platform and the objective lens after adjustment by the slide reading machine adjustment method according to the embodiment of the present application;
fig. 8 is a schematic view illustrating a positional relationship between a film reading platform and a photoelectric coupler in the adjustment method of the film reading machine according to the embodiment of the present application;
FIG. 9 is a schematic diagram of a computer device provided by an embodiment of the present application;
fig. 10 is a schematic view of an adjustment device of a film reader according to an embodiment of the present application.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments.
The terms "first," "second," "third," "fourth," and the like in the description and in the claims of the present application and in the drawings described above, if any, are used for distinguishing between similar elements and not necessarily for describing a particular sequential or chronological order. It will be appreciated that the data so used may be interchanged under appropriate circumstances such that the embodiments described herein may be practiced otherwise than as specifically illustrated or described herein. Furthermore, the terms "comprises," "comprising," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements expressly listed, but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.
The slide reader is a medical device, as shown in fig. 1, the slide reader comprises an objective lens 101 and a slide reading platform 102 which are oppositely arranged, wherein a slide 103 is placed on the slide reading platform 102, a sample, such as a stained blood sample or a body fluid sample, is dripped on the slide 103, and the objective lens 101 is connected with a camera, so that the camera can shoot the sample on the slide 103 through the objective lens 101 to observe the sample, achieve the purpose of diagnosis and the like.
Currently, when the film reading machine works, the distance between the film reading platform and the objective lens needs to be adjusted slightly, so that the objective lens finishes focusing to shoot a clear picture on the film reading platform; therefore, before fine adjustment, the initial movement positions of the film reading platform and the objective lens need to be verified, and if the initial position between the film reading platform and the objective lens is too far away, the fine adjustment time is long or even a focus cannot be found; if the initial position between the film reading platform and the objective lens is too close, the focus is not found in the fine adjustment process, and the film reading platform and the objective lens collide with each other.
In order to solve the above problems, an embodiment of the present application provides an adjustment method for a film reader, which can be used for a film reader to adjust starting positions of a film reading platform and an objective lens, and it should be noted that the film reader provided by the method in the embodiment of the present application includes an objective lens and a film reading platform which are arranged oppositely, the objective lens is used to shoot a sample on the film reading platform, the sample may be a stained blood sample or a body fluid sample, and for a specific sample, the embodiment of the present application is not limited.
The method provided in the embodiment of the present application may be used in any scheme related to adjusting the relative position of the lens, besides a film reader for medical equipment, and the embodiment of the present application is not limited thereto.
Referring to fig. 2, as shown in fig. 2, the adjustment method of the film reader provided in the embodiment of the present application includes the following steps.
201. And checking the height of the objective lens relative to the film reading platform to obtain a checking result.
In this embodiment, the step is a checking step, and the checking result is used to indicate whether the height between the slide platform and the objective lens is too close or too far, where if the distance between the slide platform and the objective lens is too far, the objective lens focusing time is longer, and if the distance between the slide platform and the objective lens is too close, the slide platform and the objective lens may collide during focusing, and therefore, the height of the objective lens relative to the slide platform needs to be controlled within a preset range.
202. And controlling the relative height between the objective lens and the initial position of the film reading platform according to the verification result.
In this embodiment, according to the verification result, the relative height between the objective lens and the initial position of the slide reading platform is controlled, so that the objective lens can complete focusing within a preset fine adjustment range in the focusing process. The adjustment of the relative height between the objective lens and the film reading platform may be to adjust the objective lens or to adjust the film reading platform, and the embodiment of the present application is not limited thereto. And controlling the relative height between the objective lens and the initial position of the film reading platform according to the verification result so that the objective lens can finish focusing within a preset micro-adjustment amplitude range in the focusing process.
In this embodiment, by the method provided by the embodiment of the present application, the relative height between the objective lens and the slide reading platform can be verified, and the relative height between the objective lens and the slide reading platform is controlled within a preset range through the adjusting step, so that the starting positions of the slide reading platform and the objective lens are verified after the slide reading machine is installed or the device of the slide reading machine is replaced, and whether the distance between the starting position of the slide reading platform and the starting position of the objective lens is appropriate can be quickly detected.
It should be noted that, in the embodiment of the present application, the adjustment of the relative distance between the objective lens and the slide reading platform includes two steps of the initial position adjustment and the fine adjustment, and in order to avoid confusion, the two concepts are described in detail herein for easy differentiation.
Firstly, adjusting the initial position.
The initial position refers to the initial position of the slide reading platform and the objective lens before the objective lens starts to acquire images.
The following embodiments of the present application do not limit the adjustment of the home position to only the home position of the reading platform, or to only the home position of the objective lens, or to both the reading platform and the objective lens.
And secondly, fine adjustment.
The fine adjustment refers to a movement process that the film reading platform starts from the initial position and moves towards the direction close to the objective lens until the objective lens finishes clear focusing on the film reading platform.
It can be understood that the fine adjustment process can also be that the film reading platform is fixed, and the objective lens starts from the initial position and moves towards the direction close to the film reading platform; or the slide reading platform and the objective lens respectively move towards the directions close to each other; meanwhile, the moving direction can be not only close to each other between the film reading platform and the objective lens, but also far away from each other.
Based on the above description, please refer to fig. 3, further, the step of verifying in step 201 may specifically include the following steps.
301. And the relative height between the objective lens and the film reading platform is finely adjusted, so that the objective lens finishes focusing.
In this embodiment, the specific implementation manner of fine adjustment of the relative height between the objective lens and the film reading platform is as follows: and controlling the relative motion between the film reading platform and the objective lens.
It should be noted that, in the process of focusing by the film reader, the first scheme may be: the film reading platform is static, and the objective lens moves to realize focusing; scheme two may also be: the objective lens is fixed, and focusing of the objective lens is achieved by movement of the reading platform relative to the objective lens, so that the embodiment of the present application is not limited, and for convenience of understanding, in the embodiment of the present application, a second scheme is taken as an example for description, and for the first scheme, implementation can be achieved based on the same principle as the second scheme, and therefore, details of the embodiment of the present application are not repeated.
Therefore, the implementation manner of the step 301 is as follows: and the film reading platform moves relative to the objective lens until the objective lens finishes focusing, and the film reading platform stops moving.
302. And acquiring a first micro-adjustment amplitude of the relative height between the objective lens and the film reading platform in the focusing step.
In this embodiment, the first fine adjustment range is a variation amount of relative movement between the objective lens and the film reading platform when the objective lens completes one-time focusing; taking the example that the objective lens is fixed and the film reading platform moves relative to the objective lens, the first micro-adjustment amplitude is the amplitude of the movement of the film reading platform from the initial movement position when the objective lens finishes focusing.
303. And judging whether the first micro-adjustment amplitude is within a preset micro-adjustment amplitude range or not to obtain a verification result.
In this embodiment, the fine adjustment range is a range preset by a user according to an actual situation, and the verification result is used to indicate: when the first micro-adjustment amplitude exceeds the upper limit of the micro-adjustment amplitude range, the distance between the objective lens and the initial position of the slide reading platform is too far; when the first fine adjustment amplitude is smaller than the lower limit of the fine adjustment amplitude range, the distance between the objective lens and the initial position of the slide reading platform is too short. However, when the first fine adjustment range is within the fine adjustment range, the initial position between the image reading platform and the objective lens is proper, and focusing can be smoothly completed between the image reading platform and the objective lens within the range.
Further, as to the adjustment method of the film reader provided by this embodiment, the embodiment of this application also provides a more detailed implementation manner, and the following message description is made with reference to the accompanying drawings.
Referring to fig. 4A, as shown in fig. 4A, a more detailed implementation of the adjustment method of the film reader provided in the embodiment of the present application includes the following steps.
401. And controlling the film reading platform to move one step relative to the objective lens from the initial position.
In this embodiment, a specific manner of adjusting the relative height between the objective lens and the slide reading platform is to control the slide reading platform to move by one step length from an initial position relative to the objective lens, where the length of one step length is a first preset distance and can be set according to an actual requirement, and the movement may be moving the slide reading platform by one step length in a direction close to the objective lens, or moving the slide reading platform by one step length in a direction away from the objective lens, which is not limited in this embodiment. For ease of understanding, the explanation is given only by taking the example of moving the reading platform in the direction of approaching the objective lens.
402. And judging whether the objective lens completes focusing or not.
In this embodiment, optionally, whether the objective lens completes focusing may be determined in an image detection manner, that is, whether the quality of an image acquired by the objective lens before and after the movement of the slide reading platform is improved is determined, and if the quality of the image is improved, the slide reading platform may continue to move, and if the quality of the image is reduced, the slide reading platform reaches a point at which focusing is completed. Referring to fig. 4B, as shown in fig. 4B, the method includes the following steps.
4021. And acquiring the first image quality when the film reading platform is positioned at the first position.
In this embodiment, the first image quality is an image quality of a sample on the image reading platform captured by the objective lens, and the first position is a position between the starting position of the image reading platform and the objective lens.
4022. And acquiring second image quality when the film reading platform is positioned at the second position.
In this embodiment, the second position is not the same as the first position, for example, the first position is an initial position of the slide reading platform, and the slide reading platform reaches the second position after moving a distance of one step toward the direction in which the objective lens is located.
4023. The first image quality is compared with the second image quality.
In this embodiment, the obtaining and comparing of the image quality may be performed by an image recognition algorithm, which is the prior art available to those skilled in the art, and the embodiment of the present application is not limited thereto.
4024. And if the second image quality is higher than the first image quality, judging that the objective lens does not finish focusing.
In this embodiment, if the second image quality is higher than the first image quality, it is described that the image quality obtained by shooting the objective lens is continuously improved in the process of moving the image reading platform to be close to the objective lens, and therefore it is determined that the image may be further improved if the image reading platform continues to move close to the objective lens, and it is determined that the objective lens is not focused.
4025. And if the second image quality is lower than the first image quality, judging that the objective lens finishes focusing when the film reading platform is at the first position.
In this embodiment, when the second image quality is lower than the first image quality, it is determined that the objective lens completes focusing when the reading platform is at the first position.
In the above steps 4021 to 4025, the image quality of the image obtained by the objective lens is continuously compared in the process that the slide reading platform moves close to the objective lens, so that when the image quality is judged to be the best, the objective lens completes focusing.
403. And if the objective lens is not focused, controlling the film reading platform to move by one step length relative to the objective lens until the objective lens is focused.
In this embodiment, taking the example that the slide reading platform moves only in the direction of approaching the objective lens, when the objective lens does not complete focusing, the slide reading platform continues to approach the objective lens by taking one step as a unit until focusing is completed, wherein, each time the slide reading platform moves by one step, the steps 4021 to 4025 are executed to determine whether the objective lens completes focusing.
It should be noted that, in the above step 4025, when the reading platform is at the second position, it is determined that the first position is the distance at which the objective lens completes focusing, and at this time, the reading platform is controlled to return to the first position, so that the adjustment of the relative height between the objective lens and the reading platform is completed, and the objective lens completes focusing.
404. And acquiring the total step length of the movement of the film reading platform from the initial position to the position of the objective lens when the focusing is completed.
In this embodiment, assuming that the reading platform moves three steps from the initial position to the direction close to the objective lens, that is, the objective lens completes focusing, the total step size at this time is 3 steps.
405. And acquiring a first fine adjustment amplitude according to the total step length.
In this embodiment, the first fine adjustment amplitude is equal to the total step length multiplied by a first preset distance, for example, according to a preset, the first preset distance moved by one step length is 2mm, the total step length is 3 steps, and then the first fine adjustment amplitude at this time is equal to 3 times 2mm and equal to 6 mm.
406. And judging whether the first micro-adjustment amplitude is in the micro-adjustment amplitude range.
In this embodiment, the determination can be specifically made in the following manner.
If the total step length is larger than the threshold value, the objective lens still cannot finish focusing, or the first fine adjustment amplitude is larger than the amplitude upper limit value, and the verification result is that the distance between the film reading platform and the objective lens is too far, as shown in fig. 5, the objective lens is 504, and a horizontal plane 501 reached by the film reading platform 503 after the movement of the first fine adjustment amplitude is above a horizontal plane 502 where the amplitude upper limit value is located, which indicates that the first fine adjustment amplitude is larger than the amplitude upper limit value;
if the first fine adjustment amplitude is smaller than the amplitude lower limit value, the verification result is that the distance between the film reading platform and the objective lens is too close, as shown in fig. 6, the objective lens is 604, the film reading platform is flat, 503, a horizontal plane 601 reached after the movement of the first fine adjustment amplitude is below a horizontal plane 602 where the amplitude lower limit value is located, which indicates that the first fine adjustment amplitude is smaller than the amplitude lower limit value;
it should be noted that the amplitude upper limit value and the amplitude lower limit value are both preset values, and a user can set the amplitude upper limit value and the amplitude lower limit value according to an actual situation.
If the first fine adjustment range is within the fine adjustment range, the verification is successful, and at this time, step 406 is directly executed, and the verification result is output as the verification success. The initial positions of the reading platform and the objective lens are both within a preset range, and the method provided by the embodiment of the application is finished without performing subsequent steps.
407. And if the checking result shows that the distance between the film reading platform and the objective lens is too far, adjusting the initial position of the film reading platform to be close to the objective lens according to the first micro-adjustment amplitude.
In this embodiment, when the verification result is that the distance between the slide platform and the objective lens is too far, as shown in fig. 5, the horizontal plane 501 reached by the slide platform after the movement of the first fine adjustment range is above the horizontal plane 502 where the upper limit value of the range is located, and at this time, the starting position of the slide reading platform is adjusted so that the horizontal plane reached by the slide reading platform after the movement of the first fine adjustment range is within the fine adjustment range, as shown in fig. 7, the objective lens is 705, after the adjustment, the horizontal plane 701 reached by the slide reading platform 706 after the movement of the first fine adjustment amplitude is above the amplitude lower limit horizontal plane 702 and below the amplitude upper limit horizontal plane 703, so that the relative height between the slide platform 706 and the objective lens 705 is adjusted to be within the fine adjustment range, in this range, there is no case of focus failure due to too far distance, nor is there a collision between the reading platform and the objective due to too close distance.
408. And if the checking result is that the distance between the film reading platform and the objective lens is too close, adjusting the initial position of the film reading platform to be far away from the objective lens according to the first micro-adjustment amplitude.
In this embodiment, when the verification result is that the distance between the slide platform and the objective lens is too close, as shown in fig. 6, the horizontal plane 601 reached by the slide platform after the movement of the first fine adjustment range is below the horizontal plane 602 where the lower limit value of the range is located, and at this time, the initial position of the slide reading platform is adjusted so that the horizontal plane reached by the slide reading platform after the movement of the first fine adjustment range is within the fine adjustment range, as shown in fig. 7, after adjustment, the horizontal plane 701 reached by the slide reading platform after the movement of the first fine adjustment amplitude is located above the amplitude lower limit horizontal plane 702 and below the amplitude upper limit horizontal plane 703, so that the relative height between the film reading platform and the objective lens is adjusted to be within the micro-adjustment range, in this range, there is no case of focus failure due to too far distance, nor is there a collision between the reading platform and the objective due to too close distance.
After the step 407 or 408 is executed, the steps 401 to 406 are executed again, at this time, since the adjustment of the step 407 or 408 is performed, the initial position of the reading platform and/or the objective lens is within the preset range, at this time, the step 409 is executed, and the verification result is output as a success.
For ease of understanding, the following detailed description of implementations of embodiments of the present application is provided in conjunction with a specific usage scenario.
The slide reader comprises a slide reading platform, an objective lens, i.e. a human-computer interaction device, for example, the human-computer interaction device at least comprises an output device and an output device, wherein the input device can be a mouse keyboard or other key devices, the output device can be a display screen, and the human-computer interaction device is preferably a touch screen with a display function. The user calls the method provided by the embodiment of the application by operating the touch screen.
After the reader is started up, before the reader starts to work, a user needs to check whether the initial position between the reading platform and the objective lens is in a proper range or not through the method provided by the embodiment of the application, so as to prevent the situation that focusing cannot be performed due to too long distance between the reading platform and the objective lens, or the situation that the objective lens collides with the reading platform in the focusing process due to too close distance between the reading platform and the objective lens.
The user triggers the verification steps provided by the embodiment of the application through the touch screen operation, and the method specifically comprises the following steps: the image reading platform moves from the initial position to the direction close to the objective lens, in the moving process, every time the image reading platform moves by one step length, a processor of the image reading machine acquires the image quality of the image acquired by the current objective lens in real time, image quality comparison is carried out, when the image quality reaches the best state and is reduced, the condition that the objective lens acquires the image with the best image quality can be judged, focusing is completed, and at the moment, the movement amplitude of the image reading platform is recorded as a first fine adjustment amplitude. In the process, the image acquired by the objective lens is displayed on the touch screen in real time, so that a user can know the focusing condition of the objective lens by observing the image quality.
After focusing is finished, a processor of the film reading machine converts the total step length of the movement of the film reading platform to obtain a first fine adjustment amplitude, and judges whether the first fine adjustment amplitude is in a fine adjustment amplitude range, wherein the fine adjustment amplitude range is a numerical value set by a user according to an actual situation, and focusing can be smoothly finished between the film reading platform and the objective lens in the range.
If the first fine tuning amplitude is within the fine tuning amplitude range, the output result is: and when the verification is successful, the specific numerical value of the first fine adjustment amplitude is used as the focal position, so that a user can know the initial position condition of the film reading platform and the objective lens by observing the group of numerical values.
If the first fine tuning amplitude is not within the fine tuning amplitude range, the output result is: and the verification fails, a specific numerical value of the first fine adjustment amplitude is displayed, and the user is prompted according to the numerical value that the distance between the initial position of the film reading platform and the objective lens is too close or too far.
Through the mode, a user can check whether the distance between the reading platform and the initial position of the objective lens is in place or not by one key only by calling the method provided by the embodiment of the application through the touch screen.
In the above process, if the verification fails, the initial position of the film reading platform or the installation position of the objective lens needs to be adjusted, and as for a specific manner of adjusting the initial position of the film reading platform, please refer to fig. 8, as shown in fig. 8, the objective lens is 804, the initial position of the film reading platform 802 is provided with the photoelectric coupler 801, the film reading platform 802 is provided with the blocking piece 803, and when the film reading platform 802 moves to the initial position, the blocking piece 803 blocks the photoelectric coupler 801, so that it can be detected that the film reading platform 802 has moved to the initial position. Therefore, the relative position of the photoelectric coupler 801 and the stop piece 803 is adjusted, so that the initial position of the reading platform 802 can be adjusted.
Aiming at the working characteristic of the film reader, the embodiment of the application provides the following two specific adjusting modes of the initial position of the film reading platform.
First, the installation position of the photocoupler 801 is adjusted.
In this embodiment, the adjustment of the initial position of the film reading platform can be realized by adjusting the installation position of the photoelectric coupler 801, specifically, if the verification result shows that the distance between the film reading platform and the objective lens is too far, the position of the photoelectric coupler is adjusted toward the direction close to the objective lens; and if the checking result shows that the distance between the film reading platform and the objective lens is too close, adjusting the position of the photoelectric coupler to the direction far away from the objective lens. The photoelectric coupler can be controlled to move up and down according to the verification result.
Second, a retractable block 803.
In this embodiment, optionally, the blocking piece 803 is a telescopic device capable of extending or shortening in the vertical direction, and when the blocking piece 803 extends, the blocking piece 803 can shield the photocoupler 801 in advance, so as to shorten the distance between the initial position and the objective lens; when the blocking piece 803 is shortened, the blocking piece 803 delays to block the photoelectric coupler 801, so that the distance between the initial position and the objective lens is prolonged, and the effect of adjusting the initial position of the film reading platform is achieved.
It should be noted that, as for the manner of extending and retracting the barrier 803, a person skilled in the art can select the manner according to his own needs, and any scheme capable of extending and retracting the barrier can be used, which is known in the art and will not be described herein again.
It should be further noted that, instead of adjusting the initial position of the reading platform, the relative height between the reading platform and the objective lens can be adjusted by adjusting the installation height of the objective lens. At this time, the adjusting step becomes the following step.
If the checking result is that the distance between the film reading platform and the objective lens is too far, adjusting the installation position of the objective lens to be close to the initial position of the film reading platform according to the first micro-adjustment amplitude;
and if the checking result is that the distance between the film reading platform and the objective lens is too close, adjusting the installation position of the objective lens to be far away from the initial position of the film reading platform according to the first micro-adjustment amplitude.
In this embodiment, the objective lens is fixedly arranged, and the slide reading platform moves relative to the objective lens, so that if the installation height of the objective lens is adjusted, the relative position between the slide reading platform and the objective lens can be adjusted.
It should be further noted that, in any of the above embodiments, in order to prevent the reading platform from colliding with the objective lens during the verification process, a distance between the starting position of the reading platform and the objective lens needs to be greater than a preset value, so as to prevent the reading platform from colliding with the objective lens during the relative movement process. The preset value can be set according to actual conditions.
It should be noted that, in the verification step performed by the method, only the distance of the movement of the film reading platform can be obtained, but the absolute distance between the film reading platform and the objective lens cannot be directly obtained, so that, in order to prevent the collision between the film reading platform and the objective lens due to too close distance in the verification process, the distance between the starting position of the film reading platform and the objective lens is greater than a preset value, so as to prevent the collision between the film reading platform and the objective lens in the relative movement process.
To sum up, the adjustment method of the film reading machine provided by the application can be used for adjusting the relative distance between the film reading platform and the objective lens in the film reading machine, and comprises the following steps: a checking step: checking the height of the objective lens relative to the film reading platform to obtain a checking result; an adjusting step: and controlling the relative height between the objective lens and the initial position of the film reading platform according to the verification result so that the objective lens can finish focusing within a preset micro-adjustment amplitude range in the focusing process. The embodiment of the application further provides a device, equipment and a medium, which can check the relative height between the objective lens and the image reading platform, so that the relative height between the objective lens and the image reading platform is controlled within a preset range through the adjusting step, and whether the initial distance between the image reading platform and the objective lens is within a proper range can be quickly checked, and the abnormal condition can be adjusted.
The above describes a scheme provided by an embodiment of the present application. It will be appreciated that the computer device, in order to implement the above-described functions, comprises corresponding hardware structures and/or software modules for performing the respective functions. Those of skill in the art will readily appreciate that the various illustrative modules and algorithm steps described in connection with the embodiments disclosed herein may be implemented as hardware or combinations of hardware and computer software. Whether a function is performed in hardware or computer software drives hardware depends upon the particular application and design constraints imposed on the solution. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present application.
Described in terms of a hardware structure, the method may be implemented by one entity device, may also be implemented by multiple entity devices together, and may also be a logic function module in one entity device, which is not specifically limited in this embodiment of the present application.
For example, the above methods may all be implemented by the computer device in fig. 9. Fig. 9 is a schematic hardware structure diagram of a computer device according to an embodiment of the present application. The computer device comprises at least one processor 901, a communication line 902, a memory 903 and at least one communication interface 904.
The processor 901 may be a general processing unit (CPU), a microprocessor, an application-specific integrated circuit (server IC), or one or more ICs for controlling the execution of programs in accordance with the present disclosure.
The communication link 902 may include a path to communicate information between the aforementioned components.
Communication interface 904 may be implemented using any device, such as a transceiver, for communicating with other devices or communication networks, such as an ethernet, a Radio Access Network (RAN), a Wireless Local Area Network (WLAN), etc.
The memory 903 may be a read-only memory (ROM) or other type of static storage device that can store static information and instructions, a Random Access Memory (RAM) or other type of dynamic storage device that can store information and instructions, an electrically erasable programmable read-only memory (EEPROM), a compact disc read-only memory (CD-ROM) or other optical disk storage, optical disk storage (including compact disc, laser disc, optical disc, digital versatile disc, blu-ray disc, etc.), magnetic disk storage media or other magnetic storage devices, or any other medium that can be used to carry or store desired program code in the form of instructions or data structures and that can be accessed by a computer, but is not limited to these. The memory may be separate and coupled to the processor via a communication line 902. The memory may also be integral to the processor.
The memory 903 is used for storing computer-executable instructions for executing the present invention, and is controlled by the processor 901 to execute. The processor 901 is configured to execute computer-executable instructions stored in the memory 903, thereby implementing the methods provided by the above-described embodiments of the present application.
Optionally, the computer-executable instructions in the embodiments of the present application may also be referred to as application program codes, which are not specifically limited in the embodiments of the present application.
In particular implementations, processor 901 may include one or more CPUs such as CPU0 and CPU1 in fig. 9 as an example.
In particular implementations, a computer device may include multiple processors, such as processor 901 and processor 907 in fig. 9, as an example. Each of these processors may be a single-core (single-CPU) processor or a multi-core (multi-CPU) processor. A processor herein may refer to one or more devices, circuits, and/or processing cores for processing data (e.g., computer program instructions).
In particular implementations, computer device may also include an output device 905 and an input device 906, as an embodiment. An output device 905, which is in communication with the processor 901, may display information in a variety of ways. For example, the output device 905 may be a Liquid Crystal Display (LCD), a Light Emitting Diode (LED) display device, a Cathode Ray Tube (CRT) display device, a projector (projector), or the like. The input device 906, which is in communication with the processor 901, may receive input from a user in a variety of ways. For example, the input device 906 may be a mouse, keyboard, touch screen device, or sensing device, among others.
The computer device may be a general purpose device or a special purpose device. In a specific implementation, the computer device may be a desktop computer, a laptop computer, a web server, a Personal Digital Assistant (PDA), a mobile phone, a tablet computer, a wireless terminal device, an embedded device, or a device with a similar structure as in fig. 9. The embodiment of the application does not limit the type of the computer equipment.
In the embodiment of the present application, the storage device may be divided into the functional units according to the above method example, for example, each functional unit may be divided corresponding to each function, or two or more functions may be integrated into one processing unit. The integrated unit can be realized in a form of hardware, and can also be realized in a form of a software functional unit. It should be noted that the division of the unit in the embodiment of the present application is schematic, and is only a logic function division, and there may be another division manner in actual implementation.
For example, in the case where the functional units are divided in an integrated manner, fig. 10 shows a schematic diagram of an adjustment device of a slide viewer.
As shown in fig. 10, an adjustment device for a film reading machine provided in an embodiment of the present application, where the film reading machine includes an objective lens and a film reading platform that are arranged oppositely, and the objective lens is used to shoot a sample on the film reading platform, and includes:
the verification unit 1001 is used for verifying the height of the objective lens relative to the film reading platform to obtain a verification result;
an adjusting unit 1002, where the adjusting unit 1002 is configured to control a relative height between the objective lens and an initial position of the film reading platform according to the verification result of the verifying unit 1001, so that the objective lens can complete focusing within a preset fine adjustment range in a focusing process.
Optionally, the verification unit 1001 includes:
focusing subunit 10011: the microscope is used for finely adjusting the relative height between the objective lens and the film reading platform so that the objective lens completes focusing;
fine tuning subunit 10012: the microscope is used for acquiring a first fine adjustment amplitude for executing the relative height between the objective lens and the slide reading platform of the focusing subunit 10011;
analysis subunit 10013: is configured to determine whether the first fine adjustment amplitude obtained by the fine adjustment subunit 10012 is within the preset fine adjustment amplitude range, so as to obtain a verification result.
Optionally, the focusing subunit 10011 is further configured to:
controlling the slide reading platform to move by one step length from the initial position relative to the objective lens, wherein the length of the step length is a first preset distance;
judging whether the objective lens completes focusing;
if not, controlling the film reading platform to move by one step length relative to the objective lens until the objective lens finishes focusing.
Optionally, the focusing subunit 10011 is further configured to:
acquiring first image quality when the film reading platform is located at a first position, wherein the first image quality is the image quality of a sample on the film reading platform shot by the objective lens, and the first position is a position between the initial position and the objective lens;
obtaining second image quality when the slide reading platform is located at a second position, wherein the second position is not the same as the first position;
and if the second image quality is lower than the first image quality, judging that the objective lens finishes focusing when the film reading platform is at the first position.
Optionally, the fine tuning subunit 10012 is further configured to:
acquiring the total step length of the movement of the film reading platform from the initial position to the position of the objective lens when the focusing is completed;
and acquiring the first fine adjustment amplitude according to the total step length, wherein the first fine adjustment amplitude is equal to the total step length multiplied by the first preset distance.
Optionally, the analyzing subunit 10013 is further configured to:
if the first fine adjustment amplitude is within the preset fine adjustment amplitude range, the verification result is successful;
and if the first micro-adjustment amplitude is larger than the upper limit value of the preset micro-adjustment amplitude or smaller than the lower limit value of the preset micro-adjustment amplitude, the verification result is verification failure.
Optionally, the analyzing subunit 10013 is further configured to:
the first fine adjustment amplitude is larger than a preset upper limit value of the fine adjustment amplitude, and the check result prompts that the distance between the film reading platform and the objective lens is too far;
and if the first micro-adjustment amplitude is smaller than a preset micro-adjustment amplitude lower limit value, the checking result prompts that the distance between the film reading platform and the objective lens is too close.
Optionally, the analyzing subunit 10013 is further configured to:
and if the total step length of the first micro-adjustment amplitude is larger than the preset maximum adjustment threshold value of the film reading platform, the objective lens still cannot finish focusing, and the checking result prompts that the distance between the film reading platform and the objective lens is too far.
Optionally, the adjusting unit 1002 is further configured to:
if the checking result indicates that the distance between the film reading platform and the objective lens is too far, adjusting the initial position to be close to the objective lens according to the first micro-adjustment amplitude;
if the checking result indicates that the distance between the film reading platform and the objective lens is too close, adjusting the initial position to be far away from the objective lens according to the first micro-adjustment amplitude;
so that the first fine adjustment amplitude is greater than the amplitude lower limit value and less than the amplitude upper limit value.
Optionally, the film reading machine is provided with a photoelectric coupler, the film reading platform is provided with a blocking piece, when the blocking piece blocks the photoelectric coupler, the film reading machine determines that the film reading platform reaches the initial position, then, the adjusting unit 1002 is further configured to:
and adjusting the relative position of the photoelectric coupler and the baffle plate so that the starting position is close to the objective lens.
Optionally, the adjusting unit 1002 is further configured to:
if the checking result is that the distance between the film reading platform and the objective lens is too far, adjusting the installation position of the objective lens to be close to the initial position of the film reading platform according to the first micro-adjustment range;
if the verification result is that the distance between the film reading platform and the objective lens is too close, adjusting the installation position of the objective lens to be far away from the initial position of the film reading platform according to the first micro-adjustment amplitude;
so that the first fine adjustment amplitude is greater than the amplitude lower limit value and less than the amplitude upper limit value.
Optionally, a distance between the starting position and the objective lens is greater than a preset value, so as to prevent collision during relative movement of the slide reading platform and the objective lens.
Further, an embodiment of the present invention also provides a computer storage medium, which includes instructions that, when executed on a computer device, cause the computer device to execute the above method.
For a detailed description of the program stored in the computer storage medium provided in the embodiments of the present application, reference may be made to the above embodiments, which are not described herein again.
The embodiments are described in a progressive manner in the specification, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. The device disclosed by the embodiment corresponds to the method disclosed by the embodiment, so that the description is simple, and the relevant points can be referred to the method part for description.
Those of skill would further appreciate that the various illustrative elements and algorithm steps described in connection with the embodiments disclosed herein may be implemented as electronic hardware, computer software, or combinations of both, and that the various illustrative components and steps have been described above generally in terms of their functionality in order to clearly illustrate this interchangeability of hardware and software. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the implementation. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present invention.
The steps of a method or algorithm described in connection with the embodiments disclosed herein may be embodied directly in hardware, in a software module executed by a processor, or in a combination of the two. A software module may reside in Random Access Memory (RAM), memory, Read Only Memory (ROM), electrically programmable ROM, electrically erasable programmable ROM, registers, hard disk, a removable disk, a CD-ROM, or any other form of storage medium known in the art.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (15)

  1. The utility model provides a slide reader adjustment method, slide reader includes relative objective and slide reader platform that sets up, objective is used for shooing the sample on the slide reader platform, its characterized in that includes:
    a checking step: checking the height of the objective lens relative to the film reading platform to obtain a checking result;
    an adjusting step: and controlling the relative height between the objective lens and the initial position of the film reading platform according to the verification result so that the objective lens can finish focusing within a preset micro-adjustment amplitude range in the focusing process.
  2. The method of claim 1, wherein the verifying step comprises:
    a focusing step: finely adjusting the relative height between the objective lens and the film reading platform to enable the objective lens to finish focusing;
    a fine adjustment amplitude obtaining step: acquiring a first micro-adjustment amplitude of the relative height between the objective lens and the film reading platform in the focusing step;
    and (3) an analysis step: and judging whether the first micro-adjustment amplitude is within the preset micro-adjustment amplitude range or not to obtain a verification result.
  3. The method of claim 2, wherein the focusing step comprises:
    controlling the film reading platform to move by one step length from the initial position relative to the objective lens, wherein the length of the step length is a first preset distance;
    judging whether the objective lens completes focusing;
    if not, controlling the film reading platform to move by one step length relative to the objective lens until the objective lens finishes focusing.
  4. The method of claim 3, wherein the determining whether the objective lens is in focus comprises:
    acquiring first image quality when the film reading platform is located at a first position, wherein the first image quality is the image quality of a sample on the film reading platform shot by the objective lens, and the first position is a position between the initial position and the objective lens;
    obtaining a second image quality when the film reading platform is located at a second position, wherein the second position and the first position are not the same;
    and if the second image quality is lower than the first image quality, judging that the objective lens finishes focusing when the film reading platform is at the first position.
  5. The method of claim 3, wherein the fine adjustment amplitude obtaining step comprises:
    acquiring the total step length of the movement of the film reading platform from the initial position to the position of the objective lens when the focusing is completed;
    and acquiring the first fine adjustment amplitude according to the total step length, wherein the first fine adjustment amplitude is equal to the total step length multiplied by the first preset distance.
  6. The method of claim 2, wherein the analyzing step comprises:
    if the first fine adjustment amplitude is within the preset fine adjustment amplitude range, the verification result is successful;
    and if the first micro-adjustment amplitude is larger than the upper limit value of the preset micro-adjustment amplitude or smaller than the lower limit value of the preset micro-adjustment amplitude, the verification result is verification failure.
  7. The method according to claim 6, wherein the step of verifying that the first trimming width is greater than the preset upper limit value or less than the preset lower limit value comprises:
    the first fine adjustment amplitude is larger than a preset upper limit value of the fine adjustment amplitude, and the check result prompts that the distance between the film reading platform and the objective lens is too far;
    and if the first micro-adjustment amplitude is smaller than a preset micro-adjustment amplitude lower limit value, the checking result prompts that the distance between the film reading platform and the objective lens is too close.
  8. The method of claim 2, wherein the analyzing step comprises:
    and if the total step length of the first fine adjustment amplitude is larger than the preset maximum adjustment threshold value of the film reading platform, the objective lens still cannot finish focusing, and the verification result prompts that the distance between the film reading platform and the objective lens is too far.
  9. The method of claim 7 or 8, wherein the adjusting step comprises:
    if the checking result indicates that the distance between the film reading platform and the objective lens is too far, adjusting the initial position to be close to the objective lens according to the first micro-adjustment amplitude;
    if the checking result indicates that the distance between the film reading platform and the objective lens is too close, adjusting the initial position to be far away from the objective lens according to the first micro-adjustment amplitude;
    so that the first fine adjustment amplitude is greater than the amplitude lower limit value and less than the amplitude upper limit value.
  10. The method as claimed in claim 7, wherein the slide reader is provided with a photoelectric coupler, and a stop piece is provided on the slide reading platform, and when the stop piece blocks the photoelectric coupler, the slide reader determines that the slide reading platform reaches a starting position, and then the adjusting of the starting position close to the objective lens according to the first fine adjustment amplitude comprises:
    and adjusting the relative position of the photoelectric coupler and the baffle plate so that the initial position is close to the objective lens.
  11. The method of claim 7, wherein the adjusting step comprises:
    if the verification result is that the distance between the film reading platform and the objective lens is too far, adjusting the installation position of the objective lens to be close to the initial position of the film reading platform according to the first micro-adjustment amplitude;
    if the verification result is that the distance between the film reading platform and the objective lens is too close, adjusting the installation position of the objective lens to be far away from the initial position of the film reading platform according to the first micro-adjustment amplitude;
    so that the first fine adjustment amplitude is greater than the amplitude lower limit value and less than the amplitude upper limit value.
  12. The method of any one of claims 3 to 9, wherein the distance between the starting position and the objective lens is greater than a preset value to prevent collision during relative movement of the scoring platform and the objective lens.
  13. The utility model provides a read piece machine adjusting device, read piece machine is including relative objective that sets up and read piece platform, objective is used for shooting read the sample on the piece platform, its characterized in that includes:
    the verifying unit is used for verifying the height of the objective lens relative to the film reading platform to obtain a verifying result;
    and the adjusting unit is used for controlling the relative height between the initial position of the objective lens and the initial position of the film reading platform according to the checking result so that the objective lens can finish focusing within a preset micro-adjustment range in the focusing process.
  14. A computer device, characterized in that the computer device comprises: an interaction device, an input/output (I/O) interface, a processor, and a memory having program instructions stored therein;
    the interaction device is used for acquiring an operation instruction input by a user;
    the processor is configured to execute program instructions stored in the memory to perform the method of any of claims 1-12.
  15. A computer-readable storage medium comprising instructions that, when executed on a computer device, cause the computer device to perform the method of any one of claims 1-12.
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