CN114432583B

CN114432583B - Microecological transplanting device for vagina

Info

Publication number: CN114432583B
Application number: CN202210370929.8A
Authority: CN
Inventors: 邹楚; 牛耀芳; 金谷雷; 胡佳林; 邹叶青; 柳丰萍; 其他发明人请求不公开姓名
Original assignee: Hangzhou Guhe Information Technology Co ltd
Current assignee: Hangzhou Guhe Information Technology Co ltd
Priority date: 2022-04-11
Filing date: 2022-04-11
Publication date: 2022-07-08
Anticipated expiration: 2042-04-11
Also published as: CN114432583A

Abstract

A vaginal microecological implant device comprising: the top of the sample collection swab is a collection end; the collection auxiliary tube is used for being placed in a collection target body, and the sample collection swab penetrates through the collection auxiliary tube to enter the collection target body to collect a sample so as to obtain a collected object; the microorganism processing device can provide a sample collecting liquid for the sample collecting swab so as to obtain a mixed liquid containing a collected substance; the bottom of the microorganism processing device is provided with a liquid outlet; the transplantation tube is provided with a liquid inlet at one end and a liquid outlet at the other end, the liquid inlet is communicated with the liquid outlet through a hose, and the transplantation tube can be placed in a target body to be transplanted so as to inject a mixed liquid containing collection materials.

Description

Microecological transplanting device for vagina

Technical Field

The invention belongs to the technical field of medical instruments, and particularly relates to a vaginal microecological transplanting device.

Background

Vaginitis is a common disease in daily life, about 30 percent of women can generate bacterial vaginitis in a lifetime, and the occurrence of vaginitis can bring a lot of discomfort to patients, such as pruritus vulvae, burning pain, abnormal fluid and the like. At the same time, vaginally infected patients will be at a 2-6 times higher risk of sexually transmitted diseases, including AIDS, than healthy individuals. It has been shown that vaginitis is associated with vaginal micro-ecological disorders, especially when there is a reduction of lactobacilli in the vagina of women. With the successful application of fecal bacteria transplantation to chronic enteritis, researchers have transplanted vaginal microorganisms for the treatment of vaginitis. However, the following problems exist during the treatment: when the specimen collection swab enters and exits the vagina through the vaginal opening, the specimen collection swab is polluted, and the secondary infection of a patient can be caused; after the specimen collection swab is removed from the vagina, anaerobic bacteria (e.g., lactobacillus and akkermansia) present in the swab may die as a result of exposure to atmospheric oxygen. These anaerobes are usually probiotics and can play a role in anti-inflammation, thereby playing a role in treating vaginitis. The above problems will directly affect the effect of vaginal microecological transplantation. Therefore, there is a need for a vaginal microecological implant device that solves the above problems.

Disclosure of Invention

The invention aims to provide a vaginal microecological transplantation device which can prevent the pollution of a specimen collection swab and reduce the contact with air.

In order to achieve the above object, the present invention provides a vaginal microecological implant device comprising:

the top of the sample collection swab is a collection end;

the collection auxiliary tube is used for being placed in a collection target body, and the sample collection swab penetrates through the collection auxiliary tube to enter the collection target body for sample collection to obtain a collected object;

the microorganism processing device is capable of providing a specimen collecting liquid for the specimen collecting swab so as to obtain a mixed liquid containing a collected substance; the bottom of the microorganism processing device is provided with a liquid outlet;

the transplantation tube is provided with a liquid inlet at one end and a liquid outlet at the other end, the liquid inlet is communicated with the liquid outlet through a hose, and the transplantation tube can be placed in a target body to be transplanted so as to inject the mixed liquid containing the collection substances.

Preferably, the specimen collection swab is a sterile cotton swab or a sterile collection brush.

Preferably, gather the auxiliary tube with the transplantation pipe all includes body and sealed lid, sealed lid pass through screw thread and sealing washer with the one end sealing connection of body, the other end of body is equipped with gathers the mouth, it has easy tear film to gather mouthful upper cover, just the diameter of gathering mouthful is greater than the biggest external diameter of swab is gathered to the sample.

Preferably, the body is bilayer structure, locates the skin outside the inlayer including inlayer and cover, easily tear the membrane cover in gather the mouth, and certainly gather the mouth and extend to the inlayer with between the skin, easily be equipped with on the tear membrane and tear the line, the body the other end is equipped with the perforation, it passes to tear the line perforate extremely outside the body, the pulling tear the line and can make easily tear the membrane and tear and split in order to expose gather the mouth.

Preferably, a connecting joint is arranged at the communicating end of the hose and the transplanting tube, and comprises a joint cover which can be connected to one end of the tube body in a threaded manner and a nozzle which is connected to the inner side of the joint cover and is arranged towards the liquid inlet; when the joint cover is connected to the pipe body, the nozzle can spray the mixed liquid containing the collected substances into the pipe body so as to enable the mixed liquid to be sprayed out through the liquid outlet;

and a control valve is arranged at the upstream of the connecting joint.

Preferably, the microbial treatment apparatus comprises:

the liquid outlet is arranged at one end of the cylinder, the liquid injection port is arranged on the outer wall of the cylinder, and the plurality of liquid injection nozzles arranged towards the center of the cylinder are arranged on the inner wall of the cylinder;

the tube cover is in threaded connection with the other end of the tube body, and the specimen collection swab can be rotatably connected with the tube cover and is concentric with the tube body;

the motor is connected to the cylinder cover and is used for driving the sample collection swab to rotate;

the vibrating component is arranged in the cylinder cover and is used for oscillating the specimen collecting swab when the specimen collecting swab rotates.

Preferably, the device also comprises a specimen collection bottle and an infusion pump;

the barrel is of a double-layer structure and comprises a first barrel wall and a second barrel wall sleeved outside the first barrel wall, an annular liquid inlet cavity is formed between the first barrel wall and the second barrel wall, a collection cavity is enclosed by the first barrel wall, and the liquid injection port penetrates through the second barrel wall and is respectively communicated with the liquid inlet cavity and the specimen collection liquid bottle; the liquid spraying nozzle penetrates through the first cylinder wall and is respectively communicated with the liquid inlet cavity and the collecting cavity;

the specimen collection liquid bottle is used for storing the specimen collection liquid, the liquid injection pump is used for enabling the specimen collection liquid in the specimen collection liquid bottle to pass through the liquid injection port to be injected into the liquid inlet cavity and to pass through the liquid injection nozzle to be sprayed out.

Preferably, the liquid filling device further comprises a controller and a flow meter, wherein the controller is used for controlling the starting and stopping of the motor, and the flow meter is used for metering the flow of the liquid filling pump;

the specimen collecting liquid is normal saline, the bottom of the first cylinder wall is of a funnel structure, and the liquid outlet is formed in the bottom of the funnel structure;

the liquid baffle plate is arranged in the first cylinder wall and perpendicular to the axial direction, and a first through hole for the specimen collection swab to penetrate through is formed in the center of the liquid baffle plate.

Preferably, the cylinder cover is a cylindrical structure with one closed end and one open end, the motor is connected to the closed end of the cylinder cover, and an output shaft of the motor faces the cylinder body and is rotatably connected with the inner wall of the cylinder cover through a first bearing;

the microbial processing device also comprises a holder, the axial section of the holder is T-shaped and comprises a transverse plate and a straight cylinder which are connected with each other, the transverse plate is in driving connection with an output shaft of the motor and is in rotating connection with the inner wall of the cylinder cover through a second bearing, and a holding hole for inserting the sample collecting swab is formed in the middle of the straight cylinder;

a clamping plate perpendicular to the axial direction is arranged on the inner wall of the cylinder cover, a second through hole for the sample collection swab to penetrate through is formed in the middle of the clamping plate, and a soft clamping layer is arranged on the inner wall of the second through hole;

the battery used for providing power for the motor is arranged in the barrel cover, and a charging interface is arranged on the outer side of the closed end of the barrel cover.

Preferably, the vibration assembly comprises at least one pair of spring pins and at least one pair of connecting seats, each connecting seat is connected to the inner wall of the cylinder cover in a vertical direction, and each spring pin extends out of one connecting seat and abuts against the straight cylinder of the clamper;

the outer wall of the straight cylinder is provided with a plurality of inner grooves which are aligned with the spring pins and are uniformly distributed along the circumferential direction, the front ends of the inner grooves are inwards and straightly sunken along the rotation direction of the motor, and the rear ends of the inner grooves are in arc transition with the outer wall of the straight cylinder; when the clamper rotates until the spring pin is positioned at the inner groove, the spring pin is ejected and continuously compressed until the next inner groove is ejected so as to oscillate the clamper.

The invention relates to a vaginal microecological transplanting device, which has the beneficial effects that: the sample is collected through the collection auxiliary tube, so that the pollution of the vaginal orifice can be avoided; the microorganism processing device and the transplanting tube realize closed transplanting, and the contact between collected objects and air can be reduced as much as possible in the transplanting process, so that vaginal microorganisms can be delivered into the vagina of a patient with vaginitis in an anaerobic and sterile environment.

Additional features and advantages of the invention will be set forth in the detailed description which follows.

Drawings

The above and other objects, features and advantages of the present invention will become more apparent by describing in more detail exemplary embodiments thereof with reference to the attached drawings, in which like reference numerals generally represent like parts throughout.

Fig. 1 shows a schematic structural view of a vaginal micro-ecological implant device according to an exemplary embodiment of the present invention;

FIG. 2 shows a schematic view of a specimen collection swab in a vaginal micro-ecological transplantation device according to an exemplary embodiment of the present invention;

FIG. 3 shows a schematic view of a specimen collection swab in a vaginal micro-ecological transplantation device according to another exemplary embodiment of the present invention;

FIG. 4 shows a schematic structural view of a collection auxiliary tube and a graft tube in the vaginal micro-ecological graft device according to an exemplary embodiment of the present invention;

FIG. 5 is a schematic view of a specimen collection swab being inserted into a collection tube of a vaginal micro-ecological transplantation device according to an exemplary embodiment of the present invention;

FIG. 6 is a schematic view showing the structure of the assembly of the graft pipe and the connection joint in the vaginal micro-ecological graft device according to an exemplary embodiment of the present invention;

FIG. 7 shows a schematic structural view of a microbial treatment device in a vaginal microecological implant device according to an exemplary embodiment of the present invention;

FIG. 8 shows a schematic structural view of a cartridge cover part of a microbial treatment device in a vaginal micro-ecological transplantation device according to an exemplary embodiment of the present invention;

fig. 9 is a schematic view showing the arrangement of a liquid ejection nozzle in the vaginal micro-ecological transplantation device according to an exemplary embodiment of the present invention;

FIG. 10 shows a schematic layout of a spring pin in a vaginal micro-ecological implant device according to an exemplary embodiment of the present invention;

FIG. 11 shows a schematic cross-sectional view of a straight cylinder of a holder in a vaginal micro-ecological implant device according to an exemplary embodiment of the present invention;

description of reference numerals:

1 specimen collection swab, 2 collection auxiliary tubes, 21 tube bodies, 22 sealing covers, 23 collection openings, 24 easy-to-tear films, 25 tear lines, 3 microbial treatment devices, 31 liquid outlets, 32 tube bodies, 321 liquid injection openings, 322 liquid injection nozzles, 323 liquid inlet cavities, 324 liquid baffle plates, 33 tube covers, 331 clamping plates, 34 motors, 35 clamping devices, 351 inner grooves, 36 first bearings, 37 second bearings, 38 vibration components, 381 spring pins, 4 transplanting tubes, 41 liquid inlet ports, 5 hoses, 51 connecting joints, 52 joint covers and 53 nozzles.

Detailed Description

Preferred embodiments of the present invention will be described in more detail below. While the following describes preferred embodiments of the present invention, it should be understood that the present invention may be embodied in various forms and should not be limited by the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art.

In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the invention and to simplify the description, but are not intended to indicate or imply that the device or element so referred to must have a particular orientation, be constructed in a particular orientation, and be operated in a particular manner, and are not to be construed as limiting the invention.

In order to solve the problems of the prior art, the present invention provides a vaginal microecological implant device, as shown in fig. 1 to 11, comprising:

the sample collection swab 1, wherein the top of the sample collection swab 1 is a collection end;

the collection auxiliary tube 2 is used for being placed in a collection target body, and the sample collection swab 1 penetrates through the collection auxiliary tube 2 to enter the collection target body for sample collection;

the microorganism processing device 3 is characterized in that the sample collecting swab 1 can be rotatably connected in the microorganism processing device 3, and the microorganism processing device 3 can provide a sample collecting liquid for the sample collecting swab 1 to obtain a mixed liquid containing a collected substance; the bottom of the microorganism processing device 3 is provided with a liquid outlet 31;

a transplantation tube 4, wherein one end of the transplantation tube 4 is provided with a liquid inlet 41, the other end of the transplantation tube 4 is provided with a liquid outlet, the liquid inlet 41 is communicated with the liquid outlet 31 through a hose 5, and the transplantation tube 4 can be placed in a target body to be transplanted so as to inject a mixed liquid containing a collection substance.

The vaginal microecological transplantation device provided by the invention collects the specimen through the collection auxiliary tube 2, so that the pollution of the vaginal orifice can be avoided; the microorganism processing device 3 and the transplanting tube 4 realize closed transplantation, and the contact between collected objects and air can be reduced as much as possible in the transplanting process, so that vaginal microorganisms can be input into the vagina of a patient suffering from vaginitis in an anaerobic and sterile environment, and the maximum curative effect of transplantation can be achieved.

Sample collection swab 1 is aseptic cotton swab or aseptic collection brush, and fig. 2 shows aseptic cotton swab's schematic diagram, and fig. 3 makes aseptic collection brush's schematic diagram, and aseptic cotton swab and aseptic collection brush are disposable product, can carry out the packing carton through disposable aseptic wrapping bag and seal, can abandon the processing after once using to guarantee safety in utilization and sterility.

In this application, gather auxiliary tube 2 and transplant pipe 4 and all include body 21 and sealed lid 22, and sealed lid 22 passes through the one end sealing connection of screw thread and sealing washer and body 21, and the other end of body 21 is equipped with gathers mouthful 23, and it has easy tear film 24 to gather mouthful 23 coats and is stamped, and the diameter of gathering mouthful 23 is greater than the biggest external diameter of sample collection swab 1 to in sample collection swab 1 wears out. The sealing cap 22 may be attached to the outer wall or the inner wall of the tube body 21, and in the embodiment shown in fig. 4, the sealing cap 22 is screw-coupled to the outer wall of the tube body 21.

In an embodiment of the present application, the tube body 21 is a double-layer structure, including an inner layer and an outer layer sleeved outside the inner layer, the easy-to-tear film 24 covers the collection port 23, and extends from the collection port 23 to between the inner layer and the outer layer, the easy-to-tear film 24 is provided with a tear line 25, the other end of the tube body 21 is provided with a through hole, the tear line 25 passes through the through hole to the outside of the tube body 21, and the pulling tear line 25 can tear the easy-to-tear film 24 to expose the collection port 23.

The collecting auxiliary tube 2 and the transplanting tube 4 have the same structure, and the universality can be improved. When the disposable collecting swab is not used, the disposable collecting swab is sealed through the sealing cover 22 and can be arranged in a disposable sterile packaging bag to keep the inside and outside sterility, when the disposable collecting swab is used, the sealing cover 22 is detached to be used as the collecting auxiliary tube 2 and can be placed in a collecting target body, the easy-tear film 24 is torn off by pulling the tear line 25, so that the specimen collecting swab 1 can be collected through the collecting auxiliary tube 2, and the specimen collecting swab 1 passes through the collecting auxiliary tube 2 to enter and exit the collecting target body, thereby avoiding the pollution of a vaginal opening or a vulva; when using as transplanting pipe 4, place its body 21 in treating the target of transplanting, patient's internal and with hose 5 intercommunication promptly, what microbial treatment device 3 provided contains that the thing mixed liquid of gathering gets into transplanting pipe 4 through hose 5, pours into the patient through the liquid outlet internal, whole transplanting process need not with the air contact, has guaranteed under anaerobism and the aseptic environment, also avoids artificial pollution simultaneously, has guaranteed vaginal microorganism or the transplantation effect of microecology.

The tearing line 25 can facilitate tearing the tear film 24, or the sealing cover 22 can be provided with a protruding structure, and the tear film 24 can be poked away by directly using the sealing cover 22 after detachment.

A connecting joint 51 is arranged at the communication end of the hose 5 and the transplanting tube 4, the connecting joint 51 comprises a joint cover 52 which can be connected with one end of the tube body 21 in a threaded manner and a nozzle 53 which is connected with the inner side of the joint cover 52 and is arranged towards the liquid inlet 41; when the joint cover 52 is connected to the tube body 21, the nozzle 53 can spray the mixed liquid containing the collection material into the tube body 21 so as to enable the mixed liquid to be sprayed out through the liquid outlet;

a control valve is arranged upstream of the connecting joint 51 and can be used for controlling the on-off of the liquid. Of course, the control valve may not be provided, and may be determined according to actual conditions.

The hose 5 can be a transparent rubber tube or a plastic tube, can also be used as a disposable article, and can be discarded after use. The joint cover 52 and the sealing cover 22 have the same specification, and are fixed with the external thread of the outer wall of the tube body 21 through the internal thread in a matching way, the joint cover 52 is provided with a hole for liquid circulation, the hose 5 is communicated with the hole, and the collected substance-containing mixed liquid passing through the hose 5 can be sprayed into the tube body 21 of the transplantation tube 4 through the nozzle 53 and flows out through the liquid outlet. The ejection speed of the nozzle 53 can be increased by increasing the injection pressure.

In the application, the collection target is a healthy person, the target to be transplanted is a vaginitis patient, and the collection object is a healthy vaginal microorganism, namely a vaginal microecology, which comprises anaerobic bacteria such as lactobacillus and bifidobacterium.

The microbial treatment apparatus 3 includes:

a cylinder 32, wherein one end of the cylinder 32 is provided with a liquid outlet 31, the outer wall of the cylinder 32 is provided with a liquid injection port 321, and the inner wall is provided with a plurality of liquid injection nozzles 322 which are arranged towards the center of the cylinder 32;

the cylinder cover 33, the cylinder cover 33 is screwed on the other end of the cylinder body 32, the sample collecting swab 1 can be rotatably connected with the cylinder cover 33 and is concentric with the cylinder body 32;

the motor 34 is connected with the cylinder cover 33 and used for driving the sample collecting swab 1 to rotate;

a vibration assembly 38, the vibration assembly 38 being disposed within the cover 33 for oscillating the specimen collection swab 1 as it is rotated.

The sample collection swab 1 rotates to enable the sample collection liquid sprayed by the liquid spraying nozzle 322 to wash the sample collection swab 1 comprehensively, and the vibrating component 38 can promote the microecology of the vagina to fall off and mix into the sample collection liquid to form a mixed liquid containing collected substances.

The vaginal micro-ecological transplantation device further comprises a specimen collection bottle (not shown) and an infusion pump (not shown);

the barrel 32 is of a double-layer structure and comprises a first barrel wall and a second barrel wall sleeved outside the first barrel wall, an annular liquid inlet cavity 323 is formed between the first barrel wall and the second barrel wall, a collection cavity is enclosed by the first barrel wall, and a liquid injection port 321 penetrates through the second barrel wall and is respectively communicated with the liquid inlet cavity 323 and the specimen collection liquid bottle; the liquid spraying nozzle 322 penetrates through the first cylinder wall and is respectively communicated with the liquid inlet cavity 323 and the collecting cavity; as shown in FIG. 7, the top of the inlet chamber 323 may be flush with the inlet 321 or slightly higher than the inlet 321, the bottom of the inlet chamber 323 may be flush with the bottommost nozzle 322 or lower than the bottommost nozzle 322, and a flushing drain may be provided at the bottom of the inlet chamber 323 for draining the residual liquid after use;

the specimen collection liquid bottle is used for storing specimen collection liquid, and the liquid injection pump is used for injecting the specimen collection liquid into the liquid inlet cavity 323 through the liquid injection port 321 and injecting the specimen collection liquid out through the liquid injection nozzle 322. The fluid nozzle 322 may be disposed at an angle, for example, toward the specimen collection swab 1, it is worth noting that the specimen collection swab 1, for example, a sterile cotton swab, is a general consumable of fixed length, and therefore, when the specimen collection swab 1 is connected to the cover 33, the position of the collection end thereof is a fixed position, and the collection of the collection end, i.e., the vaginal microecology, may be easily released due to the action of the fluid nozzle 322.

As shown in fig. 9, in an embodiment of the present application, the liquid spraying nozzles 322 may be divided into two groups, one group faces the middle portion of the specimen collection swab 1, the other group faces the collection end of the specimen collection swab 1, and each group of liquid spraying nozzles 322 is uniformly distributed along the circumferential direction, and meanwhile, the two groups of liquid spraying nozzles 322 are arranged in a staggered manner to comprehensively wash the collection end and the vicinity of the collection end of the specimen collection swab 1.

The number of the liquid ejecting nozzles 322 is not limited to the layout of 6 nozzles divided into two groups as shown in fig. 9, and may be changed in an appropriate number.

The vaginal microecological implantation device further comprises a controller (not shown) and a flow meter (not shown), wherein the controller is used for controlling the starting and stopping of the motor 34, and the flow meter is used for metering the flow of the injection pump;

the specimen collecting liquid is physiological saline, the bottom of the first cylinder wall is of a funnel structure, and the liquid outlet 31 is arranged at the bottom of the funnel structure; the funnel structure forms a mixing cavity, after the physiological saline washes down the vaginal microecology, a reflection flow is formed on the side wall of the funnel structure, and the mixed solution is discharged through the liquid outlet 31;

a liquid baffle plate 324 perpendicular to the axial direction is arranged in the first cylinder wall, and a first through hole for the sample collection swab 1 to pass through is arranged in the center of the liquid baffle plate 324.

The liquid baffle 324 prevents liquid sprayed from the nozzle 322 from splashing upward, thereby preventing contamination.

The cylinder cover 33 is a cylindrical structure with one closed end and one open end, the motor 34 is connected to the closed end of the cylinder cover 33, and the output shaft of the motor 34 is arranged towards the cylinder body 32 and is rotationally connected with the inner wall of the cylinder cover 33 through a first bearing 36;

the microbial processing device 3 further comprises a holder 35, the axial section of the holder 35 is T-shaped and comprises a transverse plate and a straight cylinder which are connected with each other, the transverse plate is in driving connection with an output shaft of the motor 34 and is rotationally connected with the inner wall of the cylinder cover 33 through a second bearing 37, and a holding hole for inserting the sample collection swab 1 is formed in the middle of the straight cylinder;

a clamping plate 331 perpendicular to the axial direction is arranged on the inner wall of the cylinder cover 33, a second through hole for the sample collection swab 1 to pass through is arranged in the middle of the clamping plate 331, and a soft clamping layer is arranged on the inner wall of the second through hole;

the cover 33 is provided with a battery for supplying power to the motor 34, and a charging interface is provided on the outer side of the closed end of the cover 33.

The grip block 331 inner wall of cover 33 is soft centre gripping layer, can improve frictional force and make the sample collection swab 1 fixed more firm, on this basis, the grip hole of holder 35 has further improved the clamping effect, can make sample collection swab 1 be fixed in it through interference fit, holder 35 rotates under motor 34's effect, and motor 34's output shaft can be connected with cover 33 through linking arm and first bearing 36. The blind end outside of cover 33 can be provided with operating button, and operating button is connected with the controller for opening of control motor 34 stops, for example, can control motor 34 operation and predetermine the time, perhaps can carry out the start-up of inching control motor 34, and operating button and the setting of the interface that charges are prior art, and concrete structure is no longer repeated.

The oscillating assembly 38 comprises at least one pair of spring pins 381 and at least one pair of connecting seats, each connecting seat is connected to the inner wall of the cover 33 in a vertical direction, and each spring pin 381 extends from one connecting seat and abuts against the straight cylinder of the holder 35;

the outer wall of the straight cylinder is provided with a plurality of inner grooves 351 which are aligned with the spring pins 381 and are uniformly distributed along the circumferential direction, the front ends of the inner grooves 351 are inwards and straightly concave along the rotation direction of the motor 34, and the rear ends of the inner grooves are in arc transition with the outer wall of the straight cylinder; when the clamper 35 is rotated until the spring pin 381 is located at the inner groove 351, the spring pin 381 is instantaneously ejected and continuously compressed until the next inner groove 351 is instantaneously ejected to oscillate the clamper 35.

The disengagement of vaginal microecological collection from the specimen collection swab 1 is facilitated by the resilient action of spring pins 381 which oscillate within a range of axial deflection which does not excessively deflect the standard collection swab 1 too far to affect retention, and the magnitude of the oscillation can be adjusted by increasing the number and preset compression of spring pins 381, as shown in fig. 10, which may be a pair of spring pins 381 disposed diametrically opposite one another, and inner grooves 351, as shown in fig. 11, which may be three to six, and are axially aligned with spring pins 381.

The vaginal microecological transplantation device has the following use process:

detaching the collection auxiliary tube 2, tearing the easy-to-tear film 24, inserting the collection auxiliary tube 2 into a collection target, namely a vagina of a healthy person, collecting vaginal secretion through the sample collection swab 1, obtaining collection containing vaginal microecology, inserting the sample collection swab 1 into a cylinder cover 33 of the microbial treatment device 3, and buckling the cylinder cover 33 and the cylinder body 32; the transplantation tube 4 and the hose 5 are connected and inserted into a target to be transplanted, namely a patient with vaginitis, then normal saline is injected through the liquid injection port 321, the motor 34 is started to rotate the specimen collection swab 1, the normal saline sprayed by the liquid spray nozzle 322 is promoted to wash the specimen collection swab 1, and collection-containing mixed liquid containing vaginal microecology enters the vagina of the patient through the liquid outlet 31, the hose 5 and the nozzle 53, so that the transplantation process is completed. The pollution of the vaginal orifice of the acquisition target to the acquisition process is avoided through the acquisition auxiliary tube 2 in the whole process, and meanwhile, the transplantation process is completed through the microorganism treatment device 3, the hose 5 and the transplantation tube 4, so that the exposure of vaginal microecology (anaerobe) in the air is reduced to a great extent, and the transplantation curative effect is good. After the use process is finished, the collection auxiliary tube 2, the transplanting tube 4 and even the hose 5 can be discarded, and then the normal saline or other disinfectant can be injected into the barrel body 32 of the microorganism processing device 3 by the liquid injection pump for washing and disinfection.

Having described embodiments of the present invention, the foregoing description is intended to be exemplary, not exhaustive, and not limited to the embodiments disclosed. Many modifications and variations will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the described embodiments.

Claims

1. A vaginal microecological implant device, comprising:

the sample collection swab (1), wherein the top of the sample collection swab (1) is a collection end;

the collection auxiliary tube (2), the collection auxiliary tube (2) is used for being placed in a collection target body, and the specimen collection swab (1) penetrates through the collection auxiliary tube (2) to enter the collection target body for specimen collection to obtain a collection object;

the microorganism processing device (3), the specimen collection swab (1) can be rotatably connected in the microorganism processing device (3), and the microorganism processing device (3) can provide specimen collection liquid for the specimen collection swab (1) to obtain collection-containing mixed liquid; a liquid outlet (31) is formed at the bottom of the microorganism treatment device (3);

a transplant tube (4), wherein one end of the transplant tube (4) is provided with a liquid inlet (41), the other end of the transplant tube is provided with a liquid outlet, the liquid inlet (41) is communicated with the liquid outlet (31) through a hose (5), and the transplant tube (4) can be placed in a target body to be transplanted so as to inject the collection-containing mixed liquid;

the microbial treatment apparatus (3) comprises:

the liquid injection device comprises a barrel (32), wherein one end of the barrel (32) is provided with the liquid outlet (31), the outer wall of the barrel (32) is provided with a liquid injection port (321), and the inner wall of the barrel is provided with a plurality of liquid injection nozzles (322) which are arranged towards the center of the barrel (32);

a barrel cover (33), wherein the barrel cover (33) is connected with the other end of the barrel body (32) in a threaded manner, and the specimen collection swab (1) is rotatably connected with the barrel cover (33) and is concentric with the barrel body (32);

a motor (34), wherein the motor (34) is connected to the cylinder cover (33) and is used for driving the sample collection swab (1) to rotate;

a vibrating assembly (38), the vibrating assembly (38) being disposed within the cartridge cover (33) for oscillating the specimen collection swab (1) as it rotates.

2. The vaginal microecological implantation device according to claim 1, wherein said specimen collection swab (1) is a sterile cotton swab or a sterile collection brush.

3. The vaginal microecological transplantation device according to claim 1, wherein each of the collection auxiliary tube (2) and the transplantation tube (4) comprises a tube body (21) and a sealing cover (22), the sealing cover (22) is connected with one end of the tube body (21) in a sealing manner through a thread and a sealing ring, the other end of the tube body (21) is provided with a collection opening (23), the collection opening (23) is covered with an easily-torn film (24), and the diameter of the collection opening (23) is larger than the maximum outer diameter of the specimen collection swab (1).

4. The vaginal microecological transplantation device according to claim 3, wherein the tube body (21) has a double-layer structure including an inner layer and an outer layer sleeved outside the inner layer, the easily torn membrane (24) covers the collection port (23) and extends from the collection port (23) to a position between the inner layer and the outer layer, a tear line (25) is disposed on the easily torn membrane (24), the other end of the tube body (21) is provided with a through hole, the tear line (25) passes through the through hole to the outside of the tube body (21), and pulling the tear line (25) can tear the easily torn membrane (24) to expose the collection port (23).

5. The vaginal microecological graft device according to claim 3, wherein the communicating end of the hose (5) with the graft tube (4) is provided with a connecting joint (51), and the connecting joint (51) comprises a joint cap (52) threadably connected to the one end of the tube body (21) and a nozzle (53) connected to the inside of the joint cap (52) and provided toward the inlet port (41); when the joint cover (52) is connected to the tube body (21), the nozzle (53) can spray the collection-containing mixed liquid into the tube body (21) so as to enable the mixed liquid to be sprayed out through the liquid outlet;

and a control valve is arranged at the upstream of the connecting joint (51).

6. The vaginal microecological transfer device according to claim 1, further comprising a specimen collection bottle and an infusion pump;

the barrel (32) is of a double-layer structure and comprises a first barrel wall and a second barrel wall sleeved outside the first barrel wall, an annular liquid inlet cavity (323) is formed between the first barrel wall and the second barrel wall, a collection cavity is enclosed by the first barrel wall, and the liquid injection port (321) penetrates through the second barrel wall and is respectively communicated with the liquid inlet cavity (323) and the specimen collection liquid bottle; the liquid spraying nozzle (322) penetrates through the first cylinder wall and is respectively communicated with the liquid inlet cavity (323) and the collecting cavity;

the specimen collection liquid bottle is used for storing the specimen collection liquid, the liquid injection pump is used for injecting the specimen collection liquid into the liquid inlet cavity (323) through the liquid injection port (321), and the liquid is sprayed out through the liquid spraying nozzle (322).

7. The vaginal microecological implantation device according to claim 6, further comprising a controller for controlling the start and stop of the motor (34) and a flow meter for metering the flow rate of the infusion pump;

the specimen collecting liquid is normal saline, the bottom of the first cylinder wall is of a funnel structure, and the liquid outlet (31) is formed in the bottom of the funnel structure;

a liquid baffle plate (324) perpendicular to the axial direction is arranged in the first cylinder wall, and a first through hole for the sample collection swab (1) to pass through is formed in the center of the liquid baffle plate (324).

8. The vaginal microecological implant device according to claim 1, wherein the cartridge cover (33) is a cylindrical structure with one closed end and one open end, the motor (34) is connected to the closed end of the cartridge cover (33), and the output shaft of the motor (34) is arranged towards the cartridge body (32) and is rotationally connected with the inner wall of the cartridge cover (33) through a first bearing (36);

the microbial processing device (3) further comprises a holder (35), the axial section of the holder (35) is T-shaped and comprises a transverse plate and a straight cylinder which are connected with each other, the transverse plate is in driving connection with an output shaft of the motor (34) and is rotatably connected with the inner wall of the cylinder cover (33) through a second bearing (37), and a holding hole for inserting the sample collection swab (1) is formed in the middle of the straight cylinder;

a clamping plate (331) perpendicular to the axial direction is arranged on the inner wall of the cylinder cover (33), a second through hole for the sample collection swab (1) to pass through is formed in the middle of the clamping plate (331), and a soft clamping layer is arranged on the inner wall of the second through hole;

the battery used for providing power for the motor (34) is arranged in the barrel cover (33), and a charging interface is arranged on the outer side of the closed end of the barrel cover (33).

9. The vaginal microecological implant device according to claim 8, characterized in that said vibrating assembly (38) comprises at least one pair of spring pins (381) and at least one pair of coupling seats, each of said coupling seats being connected perpendicular to the axial direction to the inner wall of said cap (33), each of said spring pins (381) protruding from one of said coupling seats and abutting against said straight cylinder of said holder (35);

the outer wall of the straight cylinder is provided with a plurality of inner grooves (351) which are aligned with the spring pins (381) and are uniformly distributed along the circumferential direction, and along the rotation direction of the motor (34), the front ends of the inner grooves (351) are inwards and straightly concave, and the rear ends of the inner grooves are in arc transition with the outer wall of the straight cylinder; when the clamper (35) rotates until the spring pin (381) is located at the inner groove (351), the spring pin (381) is ejected and continuously compressed until the next inner groove (351) is ejected to oscillate the clamper (35).