CN114404728A - Medicament infusion equipment - Google Patents
Medicament infusion equipment Download PDFInfo
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- CN114404728A CN114404728A CN202111662183.XA CN202111662183A CN114404728A CN 114404728 A CN114404728 A CN 114404728A CN 202111662183 A CN202111662183 A CN 202111662183A CN 114404728 A CN114404728 A CN 114404728A
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- transmission rod
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- motor
- infusion device
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- 239000003814 drug Substances 0.000 title claims abstract description 95
- 238000001802 infusion Methods 0.000 title claims abstract description 44
- 230000005540 biological transmission Effects 0.000 claims abstract description 160
- 238000002347 injection Methods 0.000 claims abstract description 28
- 239000007924 injection Substances 0.000 claims abstract description 28
- 229940079593 drug Drugs 0.000 claims description 26
- 230000033001 locomotion Effects 0.000 claims description 18
- 239000002184 metal Substances 0.000 claims description 14
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract description 100
- 102000004877 Insulin Human genes 0.000 abstract description 50
- 108090001061 Insulin Proteins 0.000 abstract description 50
- 229940125396 insulin Drugs 0.000 abstract description 50
- 239000000463 material Substances 0.000 abstract description 3
- 239000008280 blood Substances 0.000 description 31
- 210000004369 blood Anatomy 0.000 description 31
- 102000051325 Glucagon Human genes 0.000 description 13
- 108060003199 Glucagon Proteins 0.000 description 13
- MASNOZXLGMXCHN-ZLPAWPGGSA-N glucagon Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 MASNOZXLGMXCHN-ZLPAWPGGSA-N 0.000 description 13
- 229960004666 glucagon Drugs 0.000 description 13
- 238000000034 method Methods 0.000 description 10
- 238000012546 transfer Methods 0.000 description 5
- 230000001276 controlling effect Effects 0.000 description 4
- 238000000465 moulding Methods 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 238000007920 subcutaneous administration Methods 0.000 description 3
- 208000013016 Hypoglycemia Diseases 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000002218 hypoglycaemic effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 210000003815 abdominal wall Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/20—Blood composition characteristics
- A61M2230/201—Glucose concentration
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses a medicament infusion device, which belongs to the technical field of medicament infusion systems and comprises: the injector assembly comprises at least two injectors, each injector comprises a medicine cylinder, a plunger unit and a linkage piece, the medicine cylinder is used for containing medicine, one end of the plunger unit extends into the medicine cylinder and can move in the medicine cylinder to control the injection of the medicine in the medicine cylinder, and the other end of the plunger unit is positioned outside the medicine cylinder and connected with the linkage piece; the power assembly comprises a movable driving part and a transmission rod, wherein the transmission rod is provided with an actuating part, the movable driving part drives the transmission rod to linearly move, so that the actuating part can be switched between two linkage parts and drive a plunger unit of one syringe to move, and the purpose of driving different syringes to inject by one power assembly is realized by switching and matching the actuating part between the linkage parts of different syringes, so that the internal structure of the insulin pump is simplified, materials and cost are saved, the volume of the insulin pump is reduced, the weight is lightened, and the power assembly is more convenient to carry about.
Description
Technical Field
The invention relates to the technical field of medicament infusion systems, in particular to medicament infusion equipment.
Background
The injection of insulin is an effective method for treating diabetes, but the insulin needs to be injected for a long time, the injection process is painful, the problem is well relieved by the appearance of an insulin pump, and the insulin pump can continuously and uniformly deliver the insulin to subcutaneous tissues of a patient to achieve the effect of reducing blood sugar.
However, in the process of continuously injecting insulin by the insulin pump, hypoglycemia inevitably occurs to a patient, so that shock and even death and other emergency situations occur, glucagon needs to be injected to improve blood sugar so as to avoid the situations, so that the insulin pump with both insulin and glucagon is provided, the blood sugar situation of the patient is monitored by the insulin pump in real time, the type of the injected medicament is selected according to the blood sugar situation, and the injection amount of the medicament is adjusted so as to better control the stability of the blood sugar of the patient.
The injection of insulin and glucagon is accomplished respectively through setting up two drive arrangement to current insulin pump, leads to insulin pump volume great, and the molding is heavy, and manufacturing cost is high, installs loaded down with trivial details.
Disclosure of Invention
It is an object of the present invention to disclose a medicament infusion device to at least partially solve the above mentioned problems.
In order to solve the technical problems, the invention adopts the following technical scheme:
a medicament infusion device comprising:
the injector assembly comprises at least two injectors, each injector comprises a medicine cylinder, a plunger unit and a linkage piece, the medicine cylinder is used for containing medicine, one end of the plunger unit extends into the medicine cylinder and can move in the medicine cylinder to control the injection of the medicine in the medicine cylinder, and the other end of the plunger unit is positioned outside the medicine cylinder and connected with the linkage piece;
and the power assembly comprises a movable driving part and a transmission rod, wherein the transmission rod is provided with an actuating part, the movable driving part drives the transmission rod to linearly move so as to drive the actuating part to switch between the two linkage parts and to be matched and linked with the corresponding linkage part so as to drive the corresponding plunger unit to move.
The beneficial effect of this scheme of adoption:
set up two drive arrangement in the insulin pump based on prior art, accomplish the injection of insulin and glucagon respectively, lead to insulin pump volume great, the loaded down with trivial details scheduling problem of installation, through setting up transfer line and actuating piece in this scheme, and the transfer line can drive actuating piece linear movement, so that the actuating piece switches the cooperation between the linkage of different syringes, and drive the syringe that the complex linkage corresponds with it and inject, thereby realize driving the purpose that different syringes injected through a power component, insulin pump inner structure has been simplified, save material and cost, reduce the assembly degree of difficulty, and simultaneously, the volume of insulin pump has been reduced, the molding has been optimized, the weight is lightened, make it more portable.
Preferably, the movable driving member comprises an electromagnet, a permanent magnet with polarity is arranged at the end part of the transmission rod close to the electromagnet, and the transmission rod is driven to linearly move towards the direction close to or away from the electromagnet by changing the electrifying direction of a coil of the electromagnet.
According to the scheme, the transmission rod is driven to linearly move by matching of the electromagnet and the permanent magnet, the direction of the magnetic pole of the electromagnet is changed by changing the electrifying direction of the coil in an electrified state, so that the matching of the electromagnet and the permanent magnet is switched between attraction and repulsion, and the transmission rod drives the actuating piece to linearly move towards the direction close to or far away from the electromagnet. The matching driving mode of the electromagnet and the permanent magnet is adopted, the structure is simple, the environment is protected, the power on/off and the current direction are controlled, the operation is convenient, the controllability is strong, the safety and the reliability are high, and the device is very suitable for medicament infusion equipment.
Preferably, the movable driving part comprises a memory metal, the transmission rod is connected with the memory metal, the memory metal is deformed after being electrified to drive the transmission rod to linearly move, the memory metal wire has the characteristic of self-recovery at a certain temperature, the size is small, the installation space is saved, meanwhile, the transmission rod is directly connected to the metal wire, other parts matched with the transmission rod are not needed to be additionally arranged, the structure is further simplified, and the design is optimized; or the movable driving part comprises a linear driver, the linear driver comprises a telescopic rod, the transmission rod is connected with the telescopic rod, the telescopic rod drives the transmission rod to linearly move in a telescopic mode, and the telescopic rod drives the transmission rod to linearly move with high stability, so that the matching precision and stability between the actuating part and the linkage part are guaranteed.
Preferably, the plunger unit includes plunger and dwang, the plunger spiral shell is in on the dwang, plunger one end stretches into in the cartridge case, power component still includes the rotation driving piece, the rotation driving piece drive the dwang with the actuating piece rotates, the actuating piece drives the linkage with the dwang rotates, so that the plunger is in the cartridge case internal motion.
Plunger unit adopts above-mentioned structure, plunger and dwang are the screw-thread fit mode, the rotation through the dwang drives the plunger and moves in the cartridge case, can accomplish the infusion under the not high condition of moment of torsion of rotating driving piece output, energy-concerving and environment-protective, and the transmission is steady, control accuracy is high, can realize the accurate injection of syringe, wearing and tearing between the part are little, can prolong its life, reduce the replacement cost, and improve the product quality of medicament infusion equipment, promote patient and use experience.
Preferably, the rotary driving member comprises a motor, an output shaft of the motor is in transmission connection with the rotating rod, the rotary driving member is selected from the motor, and can share a circuit and a switch with the movable driving member, and the operation sequence of the movable driving member and the rotary driving member is controlled by a control unit in the medicament infusion device, so that the operation and the use of a patient are facilitated.
Preferably, the output shaft of the motor and the transmission rod are in gear engagement transmission, the gear transmission is easy to realize, the transmission precision and efficiency are high, the work is reliable, the service life is long, and the device is more suitable for a product which needs to be used for a long time without intervals and has high injection precision requirement, such as a medicament infusion device.
Preferably, the motor is perpendicular to the transmission rod, an output shaft of the motor is provided with a first gear, the transmission rod is provided with a second gear, and the first gear and the second gear are in meshing transmission so as to transmit the rotation torque of the output shaft of the motor to the transmission rod.
The actuating piece on the transmission rod needs to be matched with the linkage pieces of different injectors through movement, so that the transmission rod needs to be perpendicular to a plurality of injectors in the injector assembly, and the length of the transmission rod is larger than that of the injector assembly along the direction of the central shaft of the transmission rod, so that the motor and the injector assembly are arranged in parallel on the same side of the transmission rod, the internal structure of the medicament infusion device is optimized, the layout is reasonable, the space is saved, and the size of the medicament infusion device is favorably reduced.
Preferably, the motor and the transmission rod are arranged in parallel, a first gear is arranged on an output shaft of the motor, a second gear is arranged on the transmission rod, the first gear is meshed with the second gear to transmit the rotation torque of the output shaft of the motor to the transmission rod, the motor and the transmission rod are arranged in parallel, a third gear serving as a transmission gear is not required to be additionally arranged between the first gear and the second gear, the transmission gear can be saved, the cost is reduced, and the weight of the medicament infusion device is reduced.
Preferably, the motor and the transmission rod are arranged side by side in the axial direction of the transmission rod, an output shaft of the motor is fixedly connected with the transmission rod, the motor can linearly move along with the transmission rod, the motor and the transmission rod are directly connected and transmit, no transmission part is needed to be additionally arranged, the structure is further simplified, the part cost is saved, the loss of torque in the transmission process is reduced, and the rotation transmission efficiency is improved.
Preferably, the motor and the transmission rod are arranged side by side along the axis direction of the transmission rod, a connecting sleeve is fixedly arranged on an output shaft of the motor, the end part of the transmission rod is inserted into the connecting sleeve and can linearly move in the connecting sleeve, a circumferential limiting structure is arranged between the connecting sleeve and the transmission rod, and the motor and the transmission rod adopt the structure.
Preferably, the linkage member comprises a fourth gear, the actuating member comprises a fifth gear capable of meshing with the fourth gear, the actuating member and the linkage member both adopt gears, so that gear meshing transmission is adopted between the transmission rod and the plunger unit, the gear transmission is easy to realize, the transmission precision and efficiency are high, the operation is reliable, the service life is long, and the device is more suitable for a product which needs to be used for a long time without intervals and has high injection precision requirement, such as a medicament infusion device.
Preferably, the transmission rod comprises two fifth gears, and one of the fifth gears is meshed with one of the fourth gears and the other of the fifth gears is separated from the other of the fourth gears by the movement of the connecting rod.
Preferably, the cartridge case is including holding storehouse, storage medicine storehouse and sleeve, storage medicine storehouse with the sleeve is followed the axis direction who holds the storehouse is located side by side hold in the storehouse, the one end of plunger unit stretches into in the storage medicine storehouse, and can move in the storage medicine storehouse, the sleeve is right the plunger unit is spacing. Controlling injection of the medicament by movement of the plunger unit in the cartridge; the sleeve has a guiding function on the movement of the plunger unit so as to improve the stability of the plunger unit during movement and further maintain the stability of the injector during injection.
Preferably, the medicament infusion device further comprises a limiting part for limiting the linear moving stroke of the transmission rod, and when the transmission rod is stabilized at a certain position by limiting the moving stroke of the transmission rod, the actuating part and a certain linkage part achieve the optimal matching state so as to ensure the matching precision and the transmission efficiency and avoid damage to the parts due to over matching.
These features and advantages of the invention will be disclosed in more detail in the following detailed description and the accompanying drawings.
Drawings
The invention is further described with reference to the accompanying drawings in which:
FIG. 1 is a schematic diagram of an insulin pump according to an embodiment of the present invention.
FIG. 2 is a schematic view of the internal structure of an insulin pump in another state according to an embodiment of the present invention.
Fig. 3 is an exploded view of the inside of an insulin pump according to an embodiment of the present invention.
Fig. 4 is a schematic view of the internal structure of an insulin pump in a certain state according to an embodiment of the present invention.
FIG. 5 is a schematic diagram of the internal structure of an insulin pump in a certain state according to an embodiment of the present invention.
Reference numerals:
100. a transfusion tube;
200. an injector; 210. a cartridge; 211. an accommodating bin; 212. a medicine storage bin; 213. a sleeve; 220. a plunger unit; 221. a plunger; 222. rotating the rod; 2221. a fourth gear;
300. a mobile power assembly; 310. a transmission rod; 320. an electromagnet; 330. a permanent magnet; 340. a fifth gear;
400. a rotary power assembly; 410. a motor; 420. a first gear; 430. a second gear; 440. a third gear;
500. a limiting part.
Detailed Description
The technical solutions of the embodiments of the present invention are explained and illustrated below with reference to the drawings of the embodiments of the present invention, but the following embodiments are only preferred embodiments of the present invention, and not all embodiments. Based on the embodiments in the implementation, other embodiments obtained by those skilled in the art without any creative effort belong to the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "clockwise", "counterclockwise", and the like, indicate orientations and positional relationships based on those shown in the drawings, and are used only for convenience of description and simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be considered as limiting the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, unless otherwise specified, "a plurality" means two or more unless explicitly defined otherwise.
In the present invention, unless otherwise expressly specified or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
In the present invention, unless otherwise expressly stated or limited, "above" or "below" a first feature means that the first and second features are in direct contact, or that the first and second features are not in direct contact but are in contact with each other via another feature therebetween. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. The first feature "under", "below" and "below" the second feature includes the first feature being directly under and obliquely below the second feature, or merely indicating the level of the first feature as described in further detail below with reference to the accompanying drawings and the detailed description of the embodiment:
the present invention will be described below with reference to an insulin pump, but it will be understood by those skilled in the art that the present invention may be applied to other infusion devices that can inject two different medicaments.
An insulin pump is an insulin input device which adopts artificial intelligent control and simulates the physiological secretion mode of insulin in a mode of continuous subcutaneous insulin infusion, thereby having the effect of regulating blood sugar.
Insulin pump includes that shell, monitoring unit, the control unit, pump, syringe subassembly, transfer line 100 and annotate the needle ware and constitute, and monitoring unit real-time supervision patient's blood sugar value to transmit blood sugar value for the control unit, the control unit judges patient's blood sugar condition according to the blood sugar value received, and the injection of control syringe subassembly. The pump presses the medicament into the syringe component, the infusion tube 100 is connected with the syringe component, the pump and the syringe component are positioned in the shell, the infusion tube 100 extends out of the shell, the needle injector is arranged at the front end of the infusion tube 100 far away from the syringe 200 and pricks into the subcutaneous part of a patient, which is the abdominal wall conventionally, and then the syringe component is driven to push the medicament into the subcutaneous part of the patient.
However, in the process of continuously injecting insulin by the insulin pump, a patient can have a hypoglycemia condition, and glucagon needs to be injected to raise the blood sugar, so the injector assembly comprises two injectors 200, wherein the two injectors 200 are respectively filled with insulin and glucagon, so that the injection of insulin or glucagon can be controlled according to the monitored blood sugar of the patient. The injection of insulin and glucagon is accomplished respectively through setting up two drive arrangement to current insulin pump, can lead to insulin pump volume great, and the molding is heavy, and manufacturing cost is high, installs loaded down with trivial details.
In order to solve the technical problems in the prior art, referring to fig. 1 to 5, according to an embodiment of the present invention, by improving the structure of an insulin pump, an effect of driving different syringes 200 by using only one power assembly is achieved, and the specific structure is as follows:
each syringe 200 includes a cartridge 210, a plunger unit 220 and a linkage member, the cartridge 210 is used for holding a medicament, one end of the plunger unit 220 extends into the cartridge 210 and can move in the cartridge 210 to control the injection of the medicament in the cartridge 210, and the other end of the plunger unit 220 is located outside the cartridge 210 and connected to the linkage member; the power assembly comprises a mobile power assembly 300 and a rotary power assembly 400, the mobile power assembly 300 comprises a mobile driving part and a transmission rod 310, an actuating part is arranged on the transmission rod 310, the mobile driving part drives the transmission rod 310 to linearly move so as to drive the actuating part to switch between the two linkage parts and to be matched and linked with the corresponding linkage part, so as to drive the corresponding plunger unit 220 to move.
Through setting up transfer line 310 and actuating piece, and transfer line 310 can drive the actuating piece linear movement to make the actuating piece switch the cooperation between the linkage of different syringes 200, and drive the syringe 200 that the linkage that cooperates with it corresponds and inject, thereby realize driving the purpose that different syringes 200 injected through a power component, simplified insulin pump inner structure, save material and cost, reduce the assembly degree of difficulty, simultaneously, reduced insulin pump's volume, optimized the molding, lightened weight, make it more convenient for hand-carry.
The movable driving member in this embodiment is preferably an electromagnet 320, and the end of the transmission rod 310 close to the electromagnet 320 is provided with a permanent magnet 330 with polarity, so as to drive the transmission rod 310 to move linearly in a direction close to or away from the electromagnet 320 by changing the energizing direction of the coil of the electromagnet 320.
The matching of the electromagnet 320 and the permanent magnet 330 is adopted to drive the transmission rod 310 to linearly move, the direction of the magnetic pole of the electromagnet 320 is changed by changing the electrifying direction of the coil in the electrified state, so that the matching of the electromagnet 320 and the permanent magnet 330 is switched between attraction and repulsion, and the transmission rod 310 drives the actuating piece to linearly move towards or away from the electromagnet 320. The matching driving mode of the electromagnet 320 and the permanent magnet 330 is adopted, the structure is simple, the environment is protected, the power on/off and the current direction are controlled, the operation is convenient, the controllability is strong, the safety and the reliability are high, and the device is very suitable for medicament infusion equipment.
Certainly, in other embodiments, the movable driving member may also be a memory metal, and at this time, the driving rod 310 is connected to the memory metal, and the memory metal is deformed after being electrified to drive the driving rod 310 to linearly move, and the memory metal wire has a self-recovery characteristic at a certain temperature, and has a small volume, so as to save an installation space, and the driving rod 310 is directly connected to the metal wire, and other components matched with the metal wire are not required to be additionally arranged, so that the structure is further simplified, and the design is optimized.
Of course, in other embodiments, the movable driving member may also be a linear driver, the linear driver includes a telescopic rod, the transmission rod 310 is connected to the telescopic rod, the telescopic rod drives the transmission rod 310 to move linearly, and the telescopic rod drives the transmission rod 310 to move linearly with high stability, so as to ensure the matching precision and stability between the actuating member and the linkage member.
The cartridge 210 in this embodiment comprises a storage chamber 211, a drug storage chamber 212 and a sleeve 213, wherein the drug is stored in the drug storage chamber 212, the drug storage chamber 212 and the sleeve 213 are arranged in the storage chamber 211 side by side along the axial direction of the storage chamber 211, and one end of the plunger unit 220 extends into the drug storage chamber 212 and can move in the cartridge 210 to control the injection of the drug. The sleeve 213 limits the plunger unit 220 to guide the movement of the plunger unit 220, so that the plunger unit 220 moves axially in the medicine storage bin 212, the shaking amplitude of the plunger unit 220 is limited, the stability of the plunger unit 220 during movement is improved, and the stability of the injector 200 during injection is maintained.
The plunger unit 220 specifically comprises a plunger 221 and a rotating rod 222, wherein the plunger 221 is screwed on the rotating rod 222, and the end of the plunger extends into the medicine storage bin 212. The plunger 221 and the rotating rod 222 are in threaded fit, and the rotation of the rotating rod 222 drives the plunger 221 to move in the drug storage bin 212, so that the injection of the drug is realized.
Referring to fig. 1 to 5, in the present embodiment, the rotation rod 222 is driven to rotate by the rotation of the transmission rod 310, a transmission structure is disposed between the transmission rod 310 and the rotation rod 222, specifically, the linkage member is preferably a fourth gear 2221, the actuator includes a fifth gear 340 capable of meshing with the fourth gear 2221, both the actuator and the linkage member adopt gears, so that the transmission rod 310 and the plunger unit 220 are in gear meshing transmission, the gear transmission is easy to implement, the transmission precision and efficiency are high, the operation is reliable, the service life is long, and the present invention is more suitable for a product, such as a medicament infusion apparatus, which needs to be used for a long time without intervals and has a high requirement on the injection precision.
Since the rotation axis of the rotation rod 222 is perpendicular to the rotation axis of the transmission rod 310, and the fourth gear 2221 and the fifth gear 340 are also in vertical meshed transmission, the fourth gear 2221 and the fifth gear 340 are preferably bevel gears, and since the tooth lines of the bevel gears have directionality, two fifth gears 340 need to be arranged on the transmission rod 310 to respectively cooperate with the fourth gears 2221 on different rotation rods 222. In operation, one fifth gear 340 is engaged with one fourth gear 2221 and the other fifth gear 340 is disengaged from the other fourth gear 2221 by movement of the connecting rod to ensure that only one syringe 200 is used to inject a medicament at the same time.
In order to limit the linear moving stroke of the transmission rod 310, the insulin pump further comprises two limiting parts 500, the limiting parts 500 are fixedly arranged on the housing, the number of the limiting parts 500 is preferably two, the two limiting parts 500 respectively limit the forward and backward moving strokes of the transmission rod, so that the transmission rod 310 has two stable positions, when the transmission rod 310 is stabilized at one stable position, the actuating part and one linkage part reach the optimal matching state, when the transmission rod 310 is stabilized at the other stable position, the actuating part and the other linkage part reach the optimal matching state, the matching precision and the transmission efficiency are ensured, and meanwhile, the parts are prevented from being damaged due to over matching.
Of course, in other embodiments, the transmission of the transmission rod 310 and the rotation rod 222 is not limited to a gear engagement transmission, and other transmission modes, such as a belt transmission, may also be used.
Of course, in other embodiments, the structure and movement of the plunger unit 220 are not limited to the above-mentioned way of driving the plunger 221 and the rotating rod 222 by screw threads, and other driving ways may be adopted as long as the switching movement of the plunger units 220 of the two syringes 200 can be realized by the linear movement of the driving rod 310. If a detachable linkage is provided between the transmission rod 310 and the plunger unit 220, the transmission rod 310 can be linearly moved to connect the detachable linkage with the plunger unit 220 of one syringe 200 and pull the plunger unit 220 to move in the cartridge 210 while being disconnected from the plunger unit 220 of another syringe 200.
In order to realize the rotation of the rotation rod 222, the rotation power assembly 400 includes a rotation driving member, preferably a motor 410, an output shaft of the motor 410 is in transmission connection with the rotation rod 222, and the rotation of the output shaft of the motor 410 drives the transmission of the rotation rod 222.
The rotary drive member is optionally provided with a motor 410 which may be used in conjunction with a circuit and switch for controlling the sequence of operation of the movable drive member and the rotary drive member via a control unit in the medication delivery device for ease of operation and use by the patient.
Preferably, the output shaft of the motor 410 and the transmission rod 310 are in gear engagement transmission, the gear transmission is easy to realize, the transmission precision and efficiency are high, the work is reliable, the service life is long, and the device is more suitable for a product which needs to be used for a long time without intervals and has high injection precision requirement, such as a medicament infusion device.
The actuator on the driving rod 310 needs to move to cooperate with the linkages of different syringes 200, so that the driving rod 310 needs to be arranged perpendicular to the two syringes 200 in the syringe assembly, and the length of the driving rod 310 is greater than the width of the two syringes 200 when they are arranged side by side along the central axis of the driving rod 310, so that the motor 410 can be arranged parallel to the syringe assembly on the same side of the driving rod 310 for optimizing the internal structure of the medication delivery device, rational layout, saving space, and reducing the size of the medication delivery device.
Referring to fig. 1 to 3, when the motor 410 is disposed parallel to the injector assembly, and the injector 200 is disposed perpendicular to the transmission rod 310, the motor 410 is disposed perpendicular to the transmission rod 310, and an output shaft of the motor 410 is disposed perpendicular to the transmission rod 310, specifically, based on the direction in the drawing, the injector 200 is disposed vertically, the transmission rod 310 is disposed horizontally, and the transmission rod 310 can move horizontally, and at this time, the transmission structure of the motor 410 and the transmission rod 310 is specifically:
the output shaft of the motor 410 is provided with a first gear 420, the first gear 420 is horizontally arranged, the transmission rod 310 is provided with a second gear 430, the second gear 430 is vertically arranged, and the first gear 420 and the second gear 430 are in meshing transmission so as to transmit the rotation torque of the output shaft of the motor 410 to the transmission rod 310.
The first gear 420 and the second gear 430 may be directly engaged for transmission, or may be transmitted through an intermediate gear, specifically, a third gear 440 is disposed between the first gear 420 and the second gear 430, the third gear 440 is also vertically disposed, the first gear 420 and the third gear 440 are vertically transmitted, the third gear 440 and the second gear 430 are transmitted in parallel, so that the third gear 440 is engaged with the first gear 420 and the second gear 430 for transmission, respectively, and the rotation torque of the output shaft of the motor 410 is transmitted to the transmission rod 310.
Of course, the number between the first gear 420 and the second gear 430 is not limited to one intermediate gear, and may be two or more, and the number of the intermediate gears may be selected and set by a skilled person according to actual needs.
Of course, the gear engagement transmission of the output shaft of the motor 410 and the transmission rod 310 is not limited to the above structure, and the number and the matching manner of the gears are not limited to the above orientation and position, and in other embodiments, the number and the matching manner of the gears can be selected according to the use and transmission requirements.
Referring to fig. 4, according to an embodiment of the present invention, a motor 410 is disposed in parallel with a transmission rod 310, a first gear 420 is disposed on an output shaft of the motor 410, a second gear 430 is disposed on the transmission rod 310, the first gear 420 is engaged with the second gear 430 to transmit a rotation torque of the output shaft of the motor 410 to the transmission rod 310, the motor 410 is disposed in parallel with the transmission rod 310, and a third gear 440 serving as a transmission gear is not disposed between the first gear 420 and the second gear 430, so that the transmission gear can be saved, the cost can be reduced, and the weight of the drug infusion apparatus can be reduced.
Referring to fig. 5, according to an embodiment of the present invention, the motor 410 and the transmission rod 310 are arranged side by side along the axial direction of the transmission rod 310, and an output shaft of the motor 410 is fixedly connected to the transmission rod 310, such as a flange, so that the output shaft of the motor 410 can drive the transmission rod 310 to rotate, and the motor 410 needs to move linearly along with the transmission rod 310. The motor 410 and the transmission rod 310 are directly connected and driven without additionally arranging a transmission part, so that the structure is further simplified, the part cost is saved, the loss of torque in the transmission process is reduced, and the rotation transmission efficiency is improved.
In order to reduce the difficulty of linear movement of the transmission rod 310, preferably, a connection sleeve is fixedly arranged on an output shaft of the motor 410, the end portion of the transmission rod 310 is inserted into the connection sleeve and can linearly move in the connection sleeve, a circumferential limiting structure is arranged between the connection sleeve and the transmission rod 310, and relative rotation is not generated between the connection sleeve and the transmission rod 310, so that the output shaft of the motor 410 can drive the transmission rod 310 to rotate, meanwhile, the transmission rod 310 can linearly move in the connection sleeve, and therefore the motor 410 does not need to move along with the transmission rod 310, the stability of the drug infusion device during operation is improved, and energy consumption is reduced.
In this embodiment, for convenience of description, it is therefore preferable that the injector assembly is two injectors 200, and when the coils of the two injectors 200 are respectively filled with insulin and glucagon and the coil of the electromagnet 320 is energized in the forward direction, the actuating member is engaged with the linkage member of the injector 200 filled with insulin, and the gear is switched to the insulin gear; when the coil of the electromagnet 320 is energized in the opposite direction, the actuator engages the linkage of the glucagon containing syringe 200 and the gear is shifted to the glucagon gear.
Of course, in other embodiments, the gear may be switched to the glucagon gear when the coil of the electromagnet 320 is energized in the forward direction; when the coil of the electromagnet 320 is energized in the reverse direction, the gear is switched to the insulin gear.
Of course, in other embodiments, the syringe assembly may be provided with three or more syringes 200, depending on the actual injection needs.
The insulin pump correspondingly adopts different working procedures according to the monitored blood sugar values, and the method comprises the following specific steps:
case 1: when the control unit receives high blood sugar, checking whether the current position is an insulin position, if so, converting the difference between the current blood sugar and the target blood sugar and then injecting; if not, controlling the coil of the electromagnet 320 to be electrified in the positive direction, switching the gear to the insulin gear, and then converting the gear according to the difference value between the current blood sugar and the target blood sugar to perform injection;
case 2: when the control unit receives a lower blood sugar value, checking whether the current position is an insulin position, if so, controlling the coil of the electromagnet 320 to be electrified reversely, switching the position to a glucagon position, calculating according to the difference value between the current blood sugar and the target blood sugar, and injecting; if not, the injection is carried out after conversion according to the difference value of the current blood sugar and the target blood sugar;
case 3: when the control unit receives the blood sugar value in the normal range, the control unit carries out comprehensive judgment according to the recently received blood sugar value, if the blood sugar is reduced to the trend in the abnormal range, the gear switching method is the same as the switching method of the case 2, and the control unit carries out injection after conversion according to the difference value of the predicted blood sugar value and the target blood sugar; if the blood sugar level tends to rise to be in an abnormal range, the gear switching method is the same as the switching method of the case 1, and the injection is carried out after conversion according to the difference value of the predicted blood sugar level and the target blood sugar level.
While the foregoing is directed to embodiments of the present invention, the scope of the invention should not be limited thereby, and it will be apparent to those skilled in the art that the invention includes, but is not limited to, those illustrated in the drawings and described in the foregoing detailed description. Any modification which does not depart from the functional and structural principles of the invention is intended to be included within the scope of the claims.
Claims (14)
1. A medicament infusion device, comprising:
the injector assembly comprises at least two injectors, each injector comprises a medicine cylinder, a plunger unit and a linkage piece, the medicine cylinder is used for containing medicine, one end of the plunger unit extends into the medicine cylinder and can move in the medicine cylinder to control the injection of the medicine in the medicine cylinder, and the other end of the plunger unit is positioned outside the medicine cylinder and connected with the linkage piece;
and the power assembly comprises a movable driving part and a transmission rod, wherein the transmission rod is provided with an actuating part, the movable driving part drives the transmission rod to linearly move so as to drive the actuating part to switch between the two linkage parts and to be matched and linked with the corresponding linkage part so as to drive the corresponding plunger unit to move.
2. The medication infusion device according to claim 1, wherein said movable driving member comprises an electromagnet, and an end of said transmission rod near said electromagnet is provided with a permanent magnet having a polarity, and by changing an energizing direction of a coil of said electromagnet, said transmission rod is driven to move linearly in a direction near or away from said electromagnet.
3. The medication infusion device of claim 1, wherein said movement drive member comprises a memory metal, said drive rod being coupled to said memory metal, said memory metal being deformable upon energization to drive said drive rod to move linearly; or, the movable driving part comprises a linear driver, the linear driver comprises a telescopic rod, the transmission rod is connected with the telescopic rod, and the telescopic rod drives the transmission rod to move linearly in a telescopic mode.
4. A medicament infusion device according to any one of claims 1 to 3 wherein the plunger unit comprises a plunger and a rotatable rod, the plunger being threadedly engaged on the rotatable rod, one end of the plunger extending into the medicament cartridge, the power assembly further comprising a rotary drive member which drives the drive and actuating members to rotate, the actuating member driving the linkage member and the rotatable rod to rotate so as to cause the plunger to move within the medicament cartridge.
5. Medicament infusion device according to claim 4, wherein the rotational drive member comprises a motor, an output shaft of which is drivingly connected with the rotational rod.
6. Medicament infusion device according to claim 5, wherein the output shaft of the motor and the transmission rod are geared by a gear mesh.
7. The drug infusion device of claim 6, wherein the motor is perpendicular to the transmission rod, a first gear is disposed on an output shaft of the motor, a second gear is disposed on the transmission rod, and the first gear and the second gear are in meshing transmission to transmit the rotation torque of the output shaft of the motor to the transmission rod.
8. The medication infusion device of claim 6, wherein the motor is disposed parallel to the drive rod, wherein an output shaft of the motor is provided with a first gear, and the drive rod is provided with a second gear, wherein the first gear is engaged with the second gear to transmit rotational torque of the output shaft of the motor to the drive rod.
9. Medicament infusion device according to claim 5, wherein the motor and the transmission rod are arranged side by side in the direction of the axis of the transmission rod, the output shaft of the motor being fixedly connected to the transmission rod, the motor being linearly movable with the transmission rod.
10. The drug infusion device of claim 5, wherein the motor and the transmission rod are arranged side by side along an axial direction of the transmission rod, a connection sleeve is fixedly arranged on an output shaft of the motor, an end portion of the transmission rod is inserted into the connection sleeve and can linearly move in the connection sleeve, and a circumferential limiting structure is arranged between the connection sleeve and the transmission rod.
11. The medicament infusion device of claim 4, wherein the linkage member comprises a fourth gear and the actuator member comprises a fifth gear engageable with the fourth gear.
12. The medication infusion device of claim 11, wherein said drive link includes two of said fifth gears, one of said fifth gears being engaged with one of said fourth gears and the other of said fifth gears being disengaged from the other of said fourth gears by movement of said connecting rod.
13. The drug infusion device of any one of claims 1 to 3 and 5 to 12, wherein the drug cartridge comprises a containing bin, a drug storage bin and a sleeve, the drug storage bin and the sleeve are arranged in the containing bin side by side along the axis direction of the containing bin, one end of the plunger unit extends into the drug storage bin and can move in the drug storage bin, and the sleeve limits the plunger unit.
14. The drug infusion device of any one of claims 1 to 3 and 5 to 12 further comprising a limiting portion for limiting the linear movement stroke of the transmission rod.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111662183.XA CN114404728A (en) | 2021-12-30 | 2021-12-30 | Medicament infusion equipment |
| PCT/CN2022/107789 WO2023005901A1 (en) | 2021-07-27 | 2022-07-26 | Injection apparatus and injection system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111662183.XA CN114404728A (en) | 2021-12-30 | 2021-12-30 | Medicament infusion equipment |
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| Publication Number | Publication Date |
|---|---|
| CN114404728A true CN114404728A (en) | 2022-04-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111662183.XA Pending CN114404728A (en) | 2021-07-27 | 2021-12-30 | Medicament infusion equipment |
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| CN (1) | CN114404728A (en) |
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| WO2024011693A1 (en) * | 2022-07-14 | 2024-01-18 | 湖南千山医疗器械有限公司 | Chip-scale driving-based insulin pump |
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