CN114403881A - Lead electrode connecting device for electrocardiogram of experimental animal - Google Patents

Lead electrode connecting device for electrocardiogram of experimental animal Download PDF

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Publication number
CN114403881A
CN114403881A CN202210032860.8A CN202210032860A CN114403881A CN 114403881 A CN114403881 A CN 114403881A CN 202210032860 A CN202210032860 A CN 202210032860A CN 114403881 A CN114403881 A CN 114403881A
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Prior art keywords
clamp
lead electrode
clamp body
lead
electrode
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CN202210032860.8A
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Chinese (zh)
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梁春苗
孙庆华
王志远
王聪
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Shandong University
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Shandong University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25Bioelectric electrodes therefor
    • A61B5/251Means for maintaining electrode contact with the body
    • A61B5/254Means for maintaining electrode contact with the body by clips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25Bioelectric electrodes therefor
    • A61B5/279Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/28Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
    • A61B5/282Holders for multiple electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

The invention relates to a lead electrode connecting device of an electrocardiogram of an experimental animal, which comprises electrode clamps and a groove, wherein the electrode clamps and the groove are connected to the two ends of a lead; the electrode clamp comprises an upper clamp body and a lower clamp body which are connected in a rotating way, and the head ends of the two clamp bodies are mutually attached to form a clamp opening with a bulge; the electrode clamp comprises a limb lead electrode clamp and a chest lead electrode clamp, an upper clamp body and a lower clamp body of the chest lead electrode clamp are both made of conductor materials, the upper clamp body of the limb lead electrode clamp is made of conductor materials, and the lower clamp body is made of insulating materials; the groove is a cylindrical conductor, the rear end of the groove is connected with a lead, the front end of the groove is provided with a jack, and the jack is used for accommodating a lead wire connector of the electrocardiograph. The electrode clamp with the protrusions is clamped on the chest or four limbs of a rat, tissue damage caused by traditional sharp objects is avoided, the electrode clamp is connected with the groove through the lead, an expansion space is provided for a connector of an electrocardiograph by utilizing the opening on the groove, and the electrode clamp is prevented from being pulled and disconnected with the electrocardiograph during experimental operation.

Description

Lead electrode connecting device for electrocardiogram of experimental animal
Technical Field
The invention relates to the technical field of experimental instruments, in particular to a lead electrode connecting device for electrocardiogram of experimental animals.
Background
The statements in this section merely provide background information related to the present disclosure and may not necessarily constitute prior art.
The electrocardiogram is an important physiological index, can reflect the basic state and pathological changes of the heart, and is an important basis for judging the heart function. In research experiments on cardiac electrophysiology and the like, electrocardiogram data of experimental animals is an important observation index.
The electrocardiogram data is obtained by matching the electrocardiograph with the lead electrodes, and the lead electrodes are connected with the electrocardiograph by using the connecting device to obtain the electrocardiogram data. The lead electrode designed for human body is too large in volume, can not be fixed on four limbs of experimental animal and put the chest lead on the corresponding part of animal heart, and is easy to contact other parts of animal body or nearby objects to generate interference, so that the electrocardiogram of experimental animal can not be directly measured.
Some lead electrodes adopt small-sized metal clamps, although the lead electrodes can be fixed on limbs of animals, metal needles or similar sharp objects are needed to be used for puncturing the skin of the four limbs of the anesthetized animals, and then the electrode clamps and the metal needles are connected and fixed, so that the process is complicated, the electrodes are easy to touch surrounding objects during operation to cause interference, and laboratory personnel are also easy to be affected by the sharp objects to be accidentally punctured.
Taking a rat as an example, the inventor finds that most of the conventional electrocardiogram lead electrode clamps for the rat can only measure the data of the four limbs of the rat, and the chest lead data contains rich information reflecting the heart state. However, the chest area of the rat is small, and the chest lead is difficult to measure, while the measurement is performed by inserting the electrode needle into the chest of the rat subcutaneously in the prior art. If the insertion depth is deep in the measurement process, the tissue damage and even the heart damage can be caused, and if the insertion depth is shallow, the electrode needle fixation can be unstable, so that the electrocardiosignal interference is large.
Disclosure of Invention
In order to solve the technical problems in the prior art, the invention provides a lead electrode connecting device for electrocardiogram of experimental animals, which utilizes an electrode clamp with a bulge to clamp the chest or four limbs of the experimental animal, avoids tissue damage caused by traditional sharp objects, connects the electrode clamp with a groove through a lead, and utilizes an opening on the groove to provide an expansion space for a joint of an electrocardiogram machine, thereby preventing the electrode clamp from being pulled and disconnected with the electrocardiogram machine during experimental operation.
In order to achieve the purpose, the invention adopts the following technical scheme:
the invention provides a lead electrode connecting device of an electrocardiogram of an experimental animal, which comprises an electrode clamp and a groove, wherein the electrode clamp and the groove are connected to two ends of a lead;
the electrode clamp comprises an upper clamp body and a lower clamp body which are connected in a rotating way, and the head ends of the two clamp bodies are mutually attached to form a clamp opening with a bulge; the electrode clamp comprises a limb lead electrode clamp and a chest lead electrode clamp, an upper clamp body and a lower clamp body of the chest lead electrode clamp are both made of conductor materials, the upper clamp body of the limb lead electrode clamp is made of conductor materials, and the lower clamp body is made of insulating materials;
the groove is a cylindrical conductor, the rear end of the groove is connected with a lead, the front end of the groove is provided with a jack, and the jack is used for accommodating a lead wire connector of the electrocardiograph.
The side wall of the groove is provided with an opening arranged along the axial direction, and the outer surface of the groove is wrapped by an insulating material.
The upper clamp body and the lower clamp body of the chest lead electrode clamp are rotationally connected through a connecting shaft, and the connecting shaft is provided with a spring.
The tail ends of the upper clamp body and the lower clamp body of the chest lead electrode clamp are far away from each other to form a handheld part.
The upper clamp body and the lower clamp body of the chest lead electrode clamp are wrapped with insulating materials to form insulating layers except for the clamp opening.
The width of the tail end of the upper clamp body of the chest lead electrode clamp is not less than that of the head end of the upper clamp body, and the tail end of the lower clamp body of the chest lead electrode clamp is connected with a lead.
The upper clamp body and the lower clamp body of the limb lead electrode clamp are rotatably connected through a connecting shaft, and the connecting shaft is provided with a spring.
The tail ends of the upper clamp body and the lower clamp body of the limb lead electrode clamp are far away from each other to form a handheld part.
The upper clamp body of the limb lead electrode clamp wraps an insulating material except for the clamp opening to form an insulating layer, and the lower clamp body of the limb lead electrode clamp is made of the insulating material.
The width of the tail end of the upper clamp body of the limb lead electrode clamp is not less than that of the head end of the upper clamp body, and the tail end of the lower clamp body of the limb lead electrode clamp is connected with a lead.
Compared with the prior art, the above one or more technical schemes have the following beneficial effects:
1. electrode clamp centre gripping forms limbs and leads electrode clamp or chest and leads electrode clamp at experimental animals four limbs or chest, and the recess is connected with electrocardiograph's line joint that leads, utilizes electrode clamp's arch and rat four limbs or chest contact, replaces traditional electrode needle male mode, can not cause the injury to experimental animals, has also avoided loaded down with trivial details operation, prevents the injury to operating personnel simultaneously.
2. The groove with the opening can be matched with the lead wire connector of the electrocardiograph of common models, the problems of poor contact, falling off and the like are not easy to occur, the operation is convenient and fast, and accurate electrocardiograph data can be obtained.
3. The electrode clamp and the groove are wrapped by insulating materials, and interference caused by touching surrounding objects during operation is avoided.
4. The connecting device can be used for measuring chest lead electrocardio data and limb lead electrocardio data of a rat at the same time, and the electrocardiosignal acquisition quality is improved by utilizing the difference of the materials of the limb lead electrode clamps and the chest lead electrode clamps.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate exemplary embodiments of the invention and together with the description serve to explain the invention and not to limit the invention.
FIG. 1 is a schematic diagram of the overall structure of a connection device according to one or more embodiments of the present invention;
FIG. 2 is a schematic view of a lead wire connector configuration according to one or more embodiments of the present invention;
fig. 3(a) is a schematic top view of a groove in a connecting device according to one or more embodiments of the present invention;
fig. 3(b) is a schematic front view of a groove in a connecting device according to one or more embodiments of the present invention;
in the figure: 1. electrode clamp, 2, upper clamp body, 3, lower clamp body, 4, insulating layer, 5, connecting axle, 6, upper clamp body tail end, 7, lower clamp body tail end, 8, wire, 9, recess rear end, 91, opening, 10, jack, 11, insulating material, 12, recess, 13, lead wire connector.
Detailed Description
The invention is further described with reference to the following figures and examples.
It is to be understood that the following detailed description is exemplary and is intended to provide further explanation of the invention as claimed. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.
It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of exemplary embodiments according to the invention. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, and it should be understood that when the terms "comprises" and/or "comprising" are used in this specification, they specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof, unless the context clearly indicates otherwise.
Lead electrodes, metal conductors for obtaining electrocardiogram data.
As described in the background art, most of the electrocardiogram lead electrode clamps used in experimental animals can only measure the data of the four limbs of the animal, and the chest lead data contains abundant information reflecting the heart state. For example, in the case of a rat, the chest area of the rat is small, and chest lead data is difficult to measure, while the measurement is performed subcutaneously by inserting an electrode needle into the chest of the rat in the prior art. If the insertion depth is deep in the measurement process, the tissue damage and even the heart damage can be caused, and if the insertion depth is shallow, the electrode needle fixation can be unstable, so that the electrocardiosignal interference is large.
Therefore, the following embodiments provide a lead electrode connecting device for electrocardiogram of experimental animals, which utilizes an electrode clip with protrusions to clamp on the chest or four limbs of a rat, thereby avoiding tissue damage caused by traditional sharp objects, the electrode clip is connected with a groove through a lead, an expansion space is provided for a joint of an electrocardiogram machine by utilizing an opening on the groove, and the electrode clip is prevented from being pulled and disconnected with the electrocardiogram machine during experimental operation.
The first embodiment is as follows:
as shown in figures 1-3, a lead electrode connecting device for electrocardiogram of experimental animal comprises an electrode clamp 1 connected with both ends of a lead wire 8 and a groove 12;
the electrode clamp 1 comprises an upper clamp body 2 and a lower clamp body 3 which are rotatably connected through a connecting shaft 5, the head ends of the two clamp bodies are mutually attached to form a clamp opening, the tail ends of the two clamp bodies are mutually far away from each other to form a handheld part, the inner side of the clamp opening is provided with a bulge, and an insulating layer 4 covers the area except the clamp opening (namely the connecting shaft 5, the tail end 6 of the upper clamp body and the tail end 7 of the lower clamp body wrap the insulating layer);
in this embodiment, as shown in fig. 1, the protrusion is a blunt circular shape, a circular arc, a hemisphere or the like, and is flat and smooth in any shape, so that the injury of sharp objects such as an electrode needle to the experimental animal and the operator is avoided.
In the embodiment, the middle rear end (the connecting shaft 5 and the tail end) of the electrode clamp is wrapped by the insulating layer 4, so that on one hand, interconnection among leads is avoided when chest leads are placed, on the other hand, myoelectric interference brought by an operator is reduced, and the operator can be prevented from being injured.
When the electrode clamp 1 is clamped on the four limbs of a rat as a limb electrode clamp and is clamped on the chest of the rat as a chest lead electrode clamp, the requirements on materials and insulation are different;
specifically, the method comprises the following steps: the upper and lower clamps (i.e. the upper clamp 2 and the lower clamp 3) of the chest lead are made of conductor materials (such as metal copper), the upper clamp 2 of the limb lead is made of conductor materials (such as metal copper), and the lower clamp 3 is made of insulating materials; the spring model of being connected with connecting axle 5 is different, because the centre gripping thickness of rat limbs and chest is different, needs to utilize the elasticity that different model springs produced different, when keeping electrode holder 1 stability, prevents that the skin swelling scheduling problem from appearing in the centre gripping tension.
The length, width, opening size and volume of the limb lead electrode clamp and the chest lead electrode clamp are not limited, the parameters of the two electrode clamps can be the same or different, in the embodiment, the upper clamp body 2 and the lower clamp body 3 form a clamp with the length of 2cm, the height of 0.7cm and the maximum opening of 6mm through the connecting shaft 5, and the connecting shaft 5 is provided with a spring for resetting the opening and closing action of the electrode clamp 1.
In this embodiment, the width of the upper clip tail end 6 and the width of the lower clip tail end 7 are both 6mm, so that the pressing is convenient, the too large area of the tail ends can cause the chest of a rat not to place a plurality of chest leads, and the too small area can not be operated conveniently.
The length of the wire is not limited, and in the present embodiment, the wire 8 is a copper wire having a length of about 13cm and has an insulating layer on the outer surface.
As shown in fig. 3, the rear end 9 of the recess 12 is connected to the lead wire 8, and the front end of the recess 12 is provided with a receptacle 10, the receptacle 10 being adapted to receive a lead connector 13 of an electrocardiograph, such as the conventional type of electrocardiograph lead connector ("banana head" interface) shown in fig. 2.
The groove 12 is a cylindrical conductor, the side wall of the groove 12 is provided with an opening 91 arranged along the axial direction, and the outer surface of the groove 12 is wrapped by an insulating material 11.
In this embodiment, the diameter of recess 12 is 3mm, and the degree of depth is 1.8cm, and inner wall thickness 1mm, and the material is brass, can avoid because of the oxidation problem that plug etc. leads to many times, and recess 12 parcel insulating material 11.
In this embodiment, the width of the opening 91 is 1mm, the length is 1.5cm, the opening 91 is arranged along the axial direction of the groove 12, the groove 12 is matched with the lead wire connector 13, the opening 91 enables the groove 12 to form an expansion space for accommodating the lead wire connector 13 (banana head), and meanwhile, the groove 12 has elasticity, and the disconnection from the electrocardiograph caused by being pulled unintentionally in the experimental operation is prevented by the elasticity.
The electrode clamp 1 comprises a limb lead electrode clamp and a chest lead electrode clamp, the resistance of the two electrode clamps is close to 0, and the resistance of the whole set of connecting device is less than 0.2 ohm.
In the traditional process of measuring the electrocardiogram data of the rat, one end of a lead is connected with an electrocardiogram machine through an electrode clamp, and the other end of the lead is inserted into subcutaneous tissues of the rat through an electrode needle or a similar sharp object; the electrode clamp used for connecting the electrocardiograph originally is clamped on the chest or four limbs of a rat to be used as a chest lead electrode clamp or a limb lead electrode clamp, the other end of the lead is connected with a lead wire joint of the electrocardiograph through the groove, the advantage of small volume of the electrode clamp is exerted, meanwhile, the electrode clamp needs to be properly connected with the electrocardiograph in the traditional mode, and the clamp body with the spring can cause spring fatigue along with use, so that the connection is unreliable.
Therefore, the electrode clamp 1 of the connecting device is clamped on the four limbs or the chest of the rat to form a limb lead electrode clamp or a chest lead electrode clamp, and the groove 12 is connected with a lead wire joint 13 of an electrocardiograph; utilize the arch and the rat limb contact of electrode holder 1, replace traditional electrode needle male mode, can not cause the injury to the experimental animals, also avoided loaded down with trivial details operation, prevent the injury to operating personnel simultaneously.
The conductor parts of the limb lead electrode clamp or the chest lead electrode clamp have the same structure, and only the strength and the material of the spring of the connecting shaft are different, so that in actual use, an insulating layer can be wound at the position of the lower clamp opening of the chest lead electrode clamp to form the limb lead electrode clamp.
The device can be simultaneously used for measuring chest lead electrocardio data and limb lead electrocardio data of a rat, and improves the electrocardio signal acquisition quality by utilizing the difference of the materials of the limb lead electrode clamp and the chest lead electrode clamp.
The electrode clamp and the groove are wrapped by insulating materials, and interference caused by touching surrounding objects during operation is avoided.
The opening on the groove can be matched with a lead wire of a common-type electrocardiograph, the problems of poor contact, falling off and the like are not easy to occur, the operation is convenient and fast, and accurate electrocardiograph data can be obtained.
The whole connecting device is simple in structure and not easy to break down and damage, when in use, the limb and chest lead electrode clamps are directly clamped at the positions of the rat limb and the chest respectively, electrode needles do not need to be inserted under the skin of the limbs of the small animals, complex operation is avoided, clamping action is free of wound and infection, and no damage is caused to operating personnel and experimental animals; the insulating material is used for wrapping, so that the interference caused by the contact of the limb electrode with surrounding objects is avoided; the rat chest lead data and the limb lead data can be measured simultaneously, and the limb lead and the chest lead electrode clamps are different in material, so that the electrocardiosignal acquisition quality can be improved; the electrocardiogram data acquisition device can be matched with the lead wires of the electrocardiogram machines of the common models, is not easy to have the problems of poor contact, falling off and the like, is convenient and quick to operate, and can acquire accurate electrocardiogram data.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. A lead electrode connecting device for the electrocardiogram of an experimental animal is characterized in that: comprises an electrode clamp and a groove which are connected with the two ends of a lead;
the electrode clamp comprises an upper clamp body and a lower clamp body which are connected in a rotating way, and the head ends of the two clamp bodies are mutually attached to form a clamp opening with a bulge; the electrode clamp comprises a limb lead electrode clamp and a chest lead electrode clamp, an upper clamp body and a lower clamp body of the chest lead electrode clamp are both made of conductor materials, the upper clamp body of the limb lead electrode clamp is made of conductor materials, and the lower clamp body is made of insulating materials;
the groove is a cylindrical conductor, the rear end of the groove is connected with a lead, the front end of the groove is provided with a jack, and the jack is used for accommodating a lead wire connector of the electrocardiograph.
2. A lead electrode connecting device for electrocardiogram of experimental animal as claimed in claim 1, wherein: the side wall of the groove is provided with an opening arranged along the axial direction, and the outer surface of the groove is wrapped by an insulating material.
3. A lead electrode connecting device for electrocardiogram of experimental animal as claimed in claim 1, wherein: the upper clamp body and the lower clamp body of the chest lead electrode clamp are rotatably connected through a connecting shaft, and the connecting shaft is provided with a spring.
4. A lead electrode connecting device for electrocardiogram of experimental animal as claimed in claim 1, wherein: the tail ends of the upper clamp body and the lower clamp body of the chest lead electrode clamp are far away from each other to form a handheld part.
5. A lead electrode connecting device for electrocardiogram of experimental animal as claimed in claim 1, wherein: the upper clamp body and the lower clamp body of the chest lead electrode clamp are wrapped with insulating materials to form insulating layers except for the clamp opening.
6. A lead electrode connecting device for electrocardiogram of experimental animal as claimed in claim 1, wherein: the width of the tail end of the upper clamp body of the chest lead electrode clamp is not less than that of the head end of the upper clamp body, and the tail end of the lower clamp body of the chest lead electrode clamp is connected with a lead.
7. A lead electrode connecting device for electrocardiogram of experimental animal as claimed in claim 1, wherein: the upper clamp body and the lower clamp body of the limb lead electrode clamp are rotatably connected through a connecting shaft, and the connecting shaft is provided with a spring.
8. A lead electrode connecting device for electrocardiogram of experimental animal as claimed in claim 1, wherein: the tail ends of the upper clamp body and the lower clamp body of the limb lead electrode clamp are far away from each other to form a handheld part.
9. A lead electrode connecting device for electrocardiogram of experimental animal as claimed in claim 1, wherein: the upper clamp body of the limb lead electrode clamp wraps an insulating material except for the clamp opening to form an insulating layer, and the lower clamp body of the limb lead electrode clamp is made of the insulating material.
10. A lead electrode connecting device for electrocardiogram of experimental animal as claimed in claim 1, wherein: the width of the tail end of the upper clamp body of the limb lead electrode clamp is not less than that of the head end of the upper clamp body, and the tail end of the lower clamp body of the limb lead electrode clamp is connected with a lead.
CN202210032860.8A 2022-01-12 2022-01-12 Lead electrode connecting device for electrocardiogram of experimental animal Pending CN114403881A (en)

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Application Number Priority Date Filing Date Title
CN202210032860.8A CN114403881A (en) 2022-01-12 2022-01-12 Lead electrode connecting device for electrocardiogram of experimental animal

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Application Number Priority Date Filing Date Title
CN202210032860.8A CN114403881A (en) 2022-01-12 2022-01-12 Lead electrode connecting device for electrocardiogram of experimental animal

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Publication number Priority date Publication date Assignee Title
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JP2004344581A (en) * 2003-05-26 2004-12-09 Kawamata Inuneko Byoin:Kk Method for mounting electrode for animal and structure of electrode for animal
CN203029231U (en) * 2012-10-24 2013-07-03 深圳市凯沃尔电子有限公司 Electrocardiogram electrode device used for animals
CN205790682U (en) * 2016-06-29 2016-12-07 洛阳尹太科智能科技有限公司 Quick wiring connector, electrode fast connector and electric supply installation
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US20180132717A1 (en) * 2016-11-14 2018-05-17 Ulrich Batzer ECG Electrode and Method for Detecting an ECG Measurement Signal
CN210612121U (en) * 2019-05-06 2020-05-26 武汉华联科生物技术有限公司 Big mouse electrocardio detection device
CN210604882U (en) * 2019-08-27 2020-05-22 深圳富睿晨电子科技有限公司 Screening device for integrated circuit test data

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