CN114397334A

CN114397334A - Noninvasive blood glucose analysis system

Info

Publication number: CN114397334A
Application number: CN202111632090.2A
Authority: CN
Inventors: 信继民; 曹君
Original assignee: Lepu Medical Technology Beijing Co Ltd
Current assignee: Lepu Medical Technology Beijing Co Ltd
Priority date: 2021-12-28
Filing date: 2021-12-28
Publication date: 2022-04-26
Anticipated expiration: 2041-12-28
Also published as: CN114397334B

Abstract

The embodiment of the invention relates to a non-invasive blood sugar analysis system, which comprises: the system comprises data acquisition equipment, a mobile terminal and a server; the data acquisition equipment comprises a main control module, a signal lamp module, a data acquisition module, a Bluetooth communication module and a battery management module; the main control module is used for carrying out equipment self-checking processing on each module, carrying out equipment electric quantity management through the battery management module, carrying out active Bluetooth connection processing and passive Bluetooth connection processing through the Bluetooth communication module, carrying out data acquisition on a detection object and a detection environment through the data acquisition module to generate an acquired data set and sending the acquired data set to the mobile terminal; the mobile terminal is used for performing PPG signal display processing, sending the collected data set to the server and receiving and displaying the returned blood sugar analysis data; the server is used for carrying out blood sugar analysis to generate blood sugar analysis data and sending the blood sugar analysis data to the mobile terminal. The system can reduce the detection difficulty of the user and improve the user experience.

Description

Noninvasive blood glucose analysis system

Technical Field

The invention relates to the technical field of data processing, in particular to a non-invasive blood glucose analysis system.

Background

In the health monitoring field, blood glucose value is a very important health evaluation parameter. If the blood sugar is unstable for a long time, various organs and tissues may be affected to different degrees. The current common blood sugar value analysis means is mainly to extract human blood based on an invasive way and to perform chemical analysis on the extracted blood to obtain a blood sugar analysis value. Since such observation means may cause trauma to the human body, if the observation means is used to observe blood sugar of the human body for a long time, inconvenience, such as poor experience of wound pain and wound infection, is undoubtedly brought to the user.

Disclosure of Invention

The object of the present invention is to provide a system for noninvasive blood glucose analysis, which is to overcome the drawbacks of the prior art, and comprises: the system comprises data acquisition equipment, a mobile terminal and a server; the data acquisition equipment is used for acquiring Photoplethysmography (PPG) signals, contact heat conduction signals, body surface heat radiation signals and body surface temperature and humidity data of a detected object, and environmental light signals, environmental heat radiation signals and environmental temperature and humidity data of a detected environment; the mobile terminal is used for displaying the PPG signal, synchronously transmitting the acquired data to the server for data analysis related to blood sugar, and displaying the analysis result. The system of the invention can provide a convenient noninvasive blood glucose analysis mode for users, thereby achieving the purposes of reducing the detection difficulty of users and improving the user experience.

To achieve the above object, an embodiment of the present invention provides a system for noninvasive blood glucose analysis, including: the system comprises data acquisition equipment, a mobile terminal and a server;

the data acquisition equipment is connected with the mobile terminal; the data acquisition equipment comprises a main control module, a signal lamp module, a data acquisition module, a Bluetooth communication module and a battery management module; the main control module is respectively connected with the signal lamp module, the data acquisition module, the Bluetooth communication module and the battery management module; the main control module is used for carrying out equipment self-checking processing on each module when the equipment is started; the main control module is also used for managing the electric quantity of the equipment through the battery management module when the preset equipment state is a normal working state; the master control module is also used for performing active Bluetooth connection processing through the Bluetooth communication module when the equipment state is a normal working state; the master control module is also used for performing passive Bluetooth connection processing through the Bluetooth communication module when the equipment state is a normal working state and receives a connection request sent by the mobile terminal; the main control module is also used for acquiring data of a detection object and a detection environment through the data acquisition module to generate an acquired data set when a preset detection activation state is an activated state, and transmitting the acquired data set to the mobile terminal through the Bluetooth communication module; the collected data set comprises three groups of PPG signal collected data, environment light signal collected data, body surface thermal radiation collected data, environment thermal radiation collected data, body surface temperature collected data, body surface humidity collected data, environment temperature collected data, environment humidity collected data and contact heat conduction collected data;

the mobile terminal is connected with the server; the mobile terminal is used for carrying out PPG signal display processing on the three groups of PPG signal acquisition data; the mobile terminal is also used for sending the collected data set to the server, receiving blood sugar analysis data sent back by the server and displaying the blood sugar analysis data;

the server is used for carrying out blood sugar analysis according to the collected data set to generate the blood sugar analysis data and sending the blood sugar analysis data to the mobile terminal.

Preferably, the main control module is specifically configured to set a preset device state as a starting state when the device self-inspection processing is performed on each module; carrying out system parameter self-checking processing on preset system parameters stored in the main control module to generate a first self-checking state; performing signal lamp function self-checking processing on the signal lamp module to generate a second self-checking state; performing self-checking processing on the subunit devices on the data acquisition module to generate a third self-checking state; performing Bluetooth module self-checking processing on the Bluetooth communication module to generate a fourth self-checking state; judging whether the first self-checking state, the second self-checking state, the third self-checking state and the fourth self-checking state are all self-checking success or not; if all the equipment states are in the normal working state, the equipment states are set to be in the normal working state; if the equipment is not completely in the self-checking state, setting the equipment state as a fault state; when the equipment state is a normal working state, setting the display color of the signal lamp module to be a preset first color; and when the equipment state is that the equipment self-checking fails, setting the display color of the signal lamp module to be a preset second color.

Preferably, the main control module is specifically configured to, when the battery management module performs device power management, periodically obtain remaining battery power from the battery management module according to a preset power check frequency; when the residual battery power is not lower than a preset normal working power threshold value, setting the display color of a signal lamp of the signal lamp module to be a preset first color; and when the residual battery power is lower than the normal working power threshold, setting the equipment state to be a power shortage state.

Preferably, the main control module is specifically configured to mark the mobile terminal corresponding to the preset bluetooth paired terminal information as a target terminal and scan the target terminal when the active bluetooth connection processing is performed through the bluetooth communication module; if the target terminal is found by scanning, performing first Bluetooth pairing processing on the target terminal; and if the first Bluetooth pairing processing is successful, establishing a first data receiving and transmitting Bluetooth channel corresponding to the target terminal, and setting the signal lamp display color of the signal lamp module to be a preset third color.

Preferably, the data acquisition device is specifically configured to perform second bluetooth pairing processing with the mobile terminal when the passive bluetooth connection processing is performed through the bluetooth communication module; and if the second Bluetooth pairing processing is successful, creating a second data receiving and transmitting Bluetooth channel corresponding to the mobile terminal, and setting the signal lamp display color of the signal lamp module to be a preset third color.

Preferably, the data acquisition module comprises a three-band PPG signal acquisition unit, an ambient light signal acquisition unit, a body surface thermal radiation acquisition unit, an ambient thermal radiation acquisition unit, a body surface temperature and humidity acquisition unit, an ambient temperature and humidity acquisition unit and a contact conduction heat acquisition unit; each acquisition unit of the data acquisition module is respectively connected with the main control module;

the device of the three-band PPG signal acquisition unit specifically comprises a three-band light emitting diode array, a first lens and a first photoelectric detector; the device of the three-waveband light emitting diode array comprises three wavebands of light emitting diodes;

the device of the ambient light signal acquisition unit specifically comprises a second lens and a second photoelectric detector;

the device of the body surface thermal radiation acquisition unit is specifically a first infrared radiation temperature sensor;

the device of the environmental thermal radiation acquisition unit is specifically a second infrared radiation temperature sensor;

the device of the body surface temperature and humidity acquisition unit is specifically a first temperature and humidity sensor;

the device of the environment temperature and humidity acquisition unit is specifically a second temperature and humidity sensor;

the device of the contact conduction heat collection unit is specifically a thermistor sensor.

Preferably, the main control module is specifically configured to send corresponding data acquisition instructions to the three-band PPG signal acquisition unit, the ambient light signal acquisition unit, the body surface thermal radiation acquisition unit, the ambient thermal radiation acquisition unit, the body surface temperature and humidity acquisition unit, the ambient temperature and humidity acquisition unit, and the contact conduction thermal acquisition unit, respectively, when the data acquisition module acquires data of a detection object and a detection environment; and receiving the collected data returned by each collecting unit to form the collected data set.

Further, the three-band PPG signal acquisition unit is used for calling three light emitting diodes of the three-band led array when receiving a first data acquisition instruction, and sequentially using light of three bands to illuminate the top of the finger of the detected object; in each irradiation process, converging the transmission light rays of the finger abdomen through the first lens positioned on the finger abdomen of the detection object, and carrying out photoelectric conversion on the converged light rays through the first photoelectric detector on the other side of the first lens to generate a group of PPG signal acquisition data of corresponding wave bands; the three groups of PPG signal acquisition data are formed by the PPG signal acquisition data corresponding to the three wave bands and are sent to the main control module;

the environment light signal acquisition unit is used for calling the second photoelectric detector to perform photoelectric conversion processing on the natural light converged by the second lens when receiving a second data acquisition instruction, generating environment light signal acquisition data and sending the environment light signal acquisition data to the main control module;

the body surface thermal radiation acquisition unit is used for calling the first infrared radiation temperature sensor with a first spacing distance from the body surface of the detection object when receiving a third data acquisition instruction, acquiring a body surface thermal radiation signal of the detection object, generating body surface thermal radiation acquisition data and sending the body surface thermal radiation acquisition data to the main control module;

the environment thermal radiation acquisition unit is used for calling the second infrared radiation temperature sensor with a second spacing distance from the body surface of the detection object when receiving a fourth data acquisition instruction, acquiring a thermal radiation signal of the detection environment, generating environment thermal radiation acquisition data and sending the environmental thermal radiation acquisition data to the main control module; the second spacing distance is greater than the first spacing distance;

the body surface temperature and humidity acquisition unit is used for calling the first temperature and humidity sensor with the body surface distance smaller than a set close range threshold value from the detection object when receiving a fifth data acquisition instruction, acquiring body surface temperature and humidity change signals of the detection object, generating corresponding body surface temperature acquisition data and body surface humidity acquisition data and sending the body surface temperature and humidity acquisition data to the main control module;

the environment temperature and humidity acquisition unit is used for calling the second temperature and humidity sensor with the body surface distance to the detection object larger than a set close range threshold value when receiving a sixth data acquisition instruction, acquiring temperature and humidity change signals of the detection environment, generating corresponding environment temperature acquisition data and environment humidity acquisition data, and sending the environment temperature acquisition data and the environment humidity acquisition data to the main control module;

the contact conduction heat collection unit is used for calling the thermistor sensor in contact with the body surface of the detection object when receiving a seventh data collection instruction, collecting contact heat conduction signals of the detection object, generating corresponding contact heat conduction collection data and sending the corresponding contact heat conduction collection data to the main control module.

Further, the three bands are specifically 650nm infrared band, 940nm near infrared band and 1050nm near infrared band.

The embodiment of the invention provides a non-invasive blood sugar analysis system, which comprises: the system comprises data acquisition equipment, a mobile terminal and a server; the data acquisition equipment is used for acquiring a three-band PPG signal, a contact heat conduction signal, a body surface heat radiation signal and body surface temperature and humidity data of a detection object, and an environment light signal, an environment heat radiation signal and environment temperature and humidity data of a detection environment; the mobile terminal is used for displaying the PPG signal, synchronously transmitting the acquired data to the server for data analysis related to blood sugar, and displaying the analysis result. The system of the invention provides a convenient noninvasive blood glucose analysis mode for the user, reduces the detection difficulty of the user and improves the user experience.

Drawings

Fig. 1 is a block diagram of a non-invasive blood glucose analyzing system according to an embodiment of the present invention.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention clearer, the present invention will be described in further detail with reference to the accompanying drawings, and it is apparent that the described embodiments are only a part of the embodiments of the present invention, not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Fig. 1 is a block diagram of a non-invasive blood glucose analyzing system according to an embodiment of the present invention, and the system mainly includes: data acquisition equipment 11, mobile terminal 12 and server 13.

Data acquisition device 11

The data acquisition equipment 11 is connected with the mobile terminal 12;

the data acquisition device 11 comprises a main control module 111, a signal lamp module 112, a data acquisition module 113, a Bluetooth communication module 114 and a battery management module 115;

the main control module 111 is respectively connected with the signal lamp module 112, the data acquisition module 113, the bluetooth communication module 114 and the battery management module 115; the main control module 111 is configured to perform device self-test processing on each module when the device is powered on; the main control module 111 is further configured to perform device power management through the battery management module 115 when the preset device state is a normal operating state; the main control module 111 is further configured to perform active bluetooth connection processing through the bluetooth communication module 114 when the device status is a normal working status; the main control module 111 is further configured to perform passive bluetooth connection processing through the bluetooth communication module 114 when the device status is a normal operating status and receives a connection request sent by the mobile terminal 12; the main control module 111 is further configured to, when the preset detection activation state is the activated state, perform data acquisition on the detection object and the detection environment through the data acquisition module 113 to generate an acquired data set, and send the acquired data set to the mobile terminal 12 through the bluetooth communication module 114; the collected data set comprises three groups of PPG signal collected data, environment light signal collected data, body surface thermal radiation collected data, environment thermal radiation collected data, body surface temperature collected data, body surface humidity collected data, environment temperature collected data, environment humidity collected data and contact heat conduction collected data;

the data acquisition module 113 comprises a three-band PPG signal acquisition unit 1131, an ambient light signal acquisition unit 1132, a body surface thermal radiation acquisition unit 1133, an ambient thermal radiation acquisition unit 1134, a body surface temperature and humidity acquisition unit 1135, an ambient temperature and humidity acquisition unit 1136 and a contact conduction heat acquisition unit 1137; each acquisition unit of the data acquisition module 113 is respectively connected with the main control module 111; the three-band PPG signal acquisition unit 1131 specifically includes a three-band led array, a first lens, and a first photodetector, and the three-band led array includes three-band leds; the ambient light signal collecting unit 1132 specifically includes a second lens and a second photodetector; the device of the body surface thermal radiation acquisition unit 1133 is specifically a first infrared radiation temperature sensor; the device of the ambient thermal radiation acquisition unit 1134 is specifically a second infrared radiation temperature sensor; the device of the body surface temperature and humidity acquisition unit 1135 is specifically a first temperature and humidity sensor; the device of the ambient temperature and humidity acquisition unit 1136 is specifically a second temperature and humidity sensor; the device contacting the conductive heat acquisition unit 1137 is embodied as a thermistor sensor.

Here, the three bands are specifically a 650nm infrared band, a 940nm near infrared band, and a 1050nm near infrared band.

Here, the main control module 111 has a storage medium therein, and is configured to store system parameters related to device management, where the system parameters at least include device status parameters that reflect whether the data acquisition device 11 is in a normal operating state; the equipment state comprises four state information of a starting state, a normal working state, an electric quantity shortage state and a fault state.

In a specific implementation manner provided in this embodiment, the main control module 111 is specifically configured to set a preset device state as a start state when performing device self-test processing on each module; performing system parameter self-checking on preset system parameters stored in the main control module 111 to generate a first self-checking state; signal lamp function self-checking processing is carried out on the signal lamp module 112 to generate a second self-checking state; performing self-inspection processing on the subunit devices on the data acquisition module 113 to generate a third self-inspection state; performing bluetooth module self-checking on the bluetooth communication module 114 to generate a fourth self-checking state; judging whether the first self-checking state, the second self-checking state, the third self-checking state and the fourth self-checking state are all successful in self-checking; if all the equipment is in the normal working state, setting the equipment state as the normal working state; if the equipment is not completely in the self-checking state, setting the equipment state as a fault state; when the equipment state is a normal working state, the display color of the signal lamp module 112 is set to a preset first color; and when the device status is that the device self-test fails, the signal light display color of the signal light module 112 is set to a preset second color.

Here, the first color is regarded as green by default, the second color is regarded as red by default, and naturally, the first color and the second color may be set by using other different colors.

When the data acquisition device 11 is started, the device self-checking processing is firstly performed, the device state is set to be a starting state in the device self-checking processing process, the device state is a normal working state if the device self-checking processing is successful, and the device state is a fault state if the device self-checking processing is failed; in the self-checking process, the main control module 111 respectively performs self-checking on the main control module, the signal lamp module 112, the data acquisition module 113 and the bluetooth communication module 114; the main control module 111 actually performs self-checking processing on the system parameters by itself, namely, correctly identifies the data format and the value of the system parameters stored in the internal storage medium, if the data format or the value is found to be wrong, the self-checking fails, otherwise, the self-checking is successful, and the corresponding output state is a first self-checking state; the main control module 111 performs signal lamp function self-checking processing on the signal lamp module 112, which is to actually check whether a signal lamp turn-off/turn-on control function, a signal lamp color switching function and signal lamp light-emitting components of the signal lamp module 112 are in a normal working state, if all the functions are normal, the self-checking is successful, otherwise, the self-checking fails, and the corresponding output state is a second self-checking state; the main control module 111 performs self-inspection processing on the subunit devices of the data acquisition module 113, that is, actually, normal working states of each data unit of the data acquisition module 113 are inspected, if all the data units are normal, the self-inspection is successful, otherwise, the self-inspection fails, and a corresponding output state is a third self-inspection state; the main control module 111 performs bluetooth module self-checking processing on the bluetooth communication module 114, that is, checking on/off basic functions of the bluetooth communication module 114, if the bluetooth module is normal, the self-checking is successful, otherwise, the self-checking fails, and the corresponding output state is the fourth self-checking state.

Optionally, the main control module 111 performs self-test processing on the device again when the device state is a fault state, and counts the number of continuous self-test failures to generate the number of continuous failure failures; if the continuous failure times exceed the set failure time threshold, the continuous self-checking is stopped, the signal lamp of the signal lamp module 112 is kept on for a long time, and the second color is used as the color of the signal lamp.

Here, the threshold of the number of failures may be set to 0, 1 or 3 times, and if the threshold of the number of failures is set to 0 times, the self-test is not performed when the equipment status is in the failure status, if the threshold of the number of failures is set to 1 time, the self-test may be performed once when the equipment status is in the failure status, and if the threshold of the number of failures is set to 3 times, the maximum number of consecutive self-tests when the equipment status is in the failure status is 3, and may be set separately according to the specific implementation requirements.

Optionally, if a failure that the device cannot continue to operate normally due to other reasons occurs in the working process after the self-checking of the data acquisition device 11 is successful, the device state may also be changed to the failure state, and the main control module 111 performs the self-checking of the device again.

In another specific implementation manner provided in this embodiment, the main control module 111 is specifically configured to, when performing device power management through the battery management module 115, periodically obtain the remaining battery power from the battery management module 115 according to a preset power check frequency; when the remaining battery power is not lower than the preset normal working power threshold, setting the signal lamp display color of the signal lamp module 112 to be a preset first color; and when the residual battery power is lower than the normal working power threshold, setting the equipment state as a power shortage state.

Here, when the data acquisition device 11 is in a normal operating state after the device self-test is successful, the device power management is performed, that is, the real-time remaining battery power of the device is cyclically identified, and the cycle frequency is the power check frequency; if the current real-time remaining battery power is sufficient to support the normal operation of the device, the color of the signal lamp module 112 remains the first color, and if the remaining battery power is not sufficient to support the normal operation of the device, the device status is set to the power shortage status.

Optionally, the main control module 111 may be further configured to switch the color of the signal lamp module 112 to yellow or orange when the device status is set to the insufficient power status, and send the insufficient power information to the mobile terminal 12 in a status that the data acquisition device 11 has established a connection with the mobile terminal 12.

In another specific implementation manner provided in this embodiment, the main control module 111 is specifically configured to mark the mobile terminal 12 corresponding to the preset bluetooth paired terminal information as a target terminal and scan the target terminal when performing active bluetooth connection processing through the bluetooth communication module 114; if the target terminal is found by scanning, performing first Bluetooth pairing processing on the target terminal; if the first bluetooth pairing process is successful, a first data receiving and transmitting bluetooth channel corresponding to the target terminal is created, and the signal lamp display color of the signal lamp module 112 is set to a preset third color.

In another specific implementation manner provided in this embodiment, the data acquisition device 11 is specifically configured to perform a second bluetooth pairing process with the mobile terminal 12 when performing a passive bluetooth connection process through the bluetooth communication module 114; if the second bluetooth pairing process is successful, a second bluetooth data channel corresponding to the mobile terminal 12 is created, and the signal light display color of the signal light module 112 is set to a preset third color.

Here, the third color defaults to blue, and naturally, other colors may be selected for setting.

Here, the data acquisition device 11 is preset with bluetooth paired terminal information of the mobile terminal 12 bound and matched with the data acquisition device, where the bluetooth paired terminal information includes a device identifier of the mobile terminal 12 and a corresponding bluetooth pairing code; the wireless connection mode of the data acquisition equipment 11 and the mobile terminal 12 is specifically a Bluetooth connection mode; the embodiment of the invention provides two connection modes when processing a specific Bluetooth connection process: an active connection mode and a passive connection mode.

For the active connection mode, the actual situation is that when the power-on self-test of the data acquisition device 11 is successful and the remaining battery power is sufficient to support the device to normally work, that is, the device state is kept in a normal working state, the data acquisition device 11 automatically scans and polls the peripheral bluetooth devices; if the mobile terminal 12 corresponding to the device identifier of the bluetooth pairing terminal information is scanned, the mobile terminal is used as a target terminal, and the bluetooth pairing code of the bluetooth pairing terminal information is used for carrying out code pairing operation according to a known bluetooth matching device code pairing processing flow, namely first bluetooth pairing processing; if the first bluetooth pairing process is successful, a corresponding data channel is locally established on the data acquisition device 11 as a first data receiving and transmitting bluetooth channel for taking charge of data sending and receiving operations between the data acquisition device 11 and the mobile terminal 12; meanwhile, the signal light display color of the signal light module 112 is set to a preset third color, so that the connection with the mobile terminal is displayed to the user, that is, the detection object; after the signal light display color of the signal light module 112 is set to the third color, the signal light is in a long-lighting state by default when the bluetooth connection is not interrupted.

For the passive connection mode, if the data acquisition device 11 does not find the mobile terminal 12 matched with the bluetooth pairing terminal information in the first active connection processing process after the power-on self-test is successful, the active scanning connection operation is not continued, but the device identification is set to be in a visible state of surrounding devices, and corresponding passive bluetooth connection processing is performed when connection requests sent by other bluetooth devices are received; in the process of passive bluetooth connection processing, the data acquisition device 11 firstly performs second bluetooth pairing processing with the mobile terminal 12, specifically, compares code matching parameters in a connection instruction sent by the mobile terminal 12 by using a bluetooth code matching code of bluetooth pairing terminal information, if the two codes are matched, the second bluetooth pairing processing is successful, otherwise, the second bluetooth pairing processing fails; if the second bluetooth pairing process is successful, a corresponding data channel is locally created on the data acquisition device 11 and used as a second data receiving and transmitting bluetooth channel for taking charge of data sending and receiving operations between the data acquisition device 11 and the mobile terminal 12; meanwhile, the signal light display color of the signal light module 112 is set to a preset third color, so that the connection with the mobile terminal is displayed to the user, that is, the detection object; after the signal light display color of the signal light module 112 is set to the third color, the signal light is in a long-lighting state by default when the bluetooth connection is not interrupted.

The system parameters related to device management stored in the main control module 111 further include a detection activation state parameter that reflects a working state of the device in a detection stage; the detection activation state comprises three state information of disconnection state, non-activation state and activation state.

The main control module 111 is also used for performing handover management on the detected activation state.

In another specific implementation manner provided in this embodiment, the main control module 111 is specifically configured to set the detection activation state to a disconnection state when connection with the mobile terminal 12 is not established yet when performing handover management on the detection activation state; setting the detection activation state to the non-activation state when establishing a connection with the mobile terminal 12; when receiving a detection instruction sent by the mobile terminal 12, setting the detection activation state to the activated state; when the detection activation state is the activated state, immediately starting a data acquisition and processing flow of the detection object and the detection environment to obtain an acquisition data set comprising three groups of PPG signal acquisition data, environmental light signal acquisition data, body surface thermal radiation acquisition data, environmental thermal radiation acquisition data, body surface temperature acquisition data, body surface humidity acquisition data, environmental temperature acquisition data, environmental humidity acquisition data and contact thermal conduction acquisition data, and sending the acquisition data set to the mobile terminal 12; upon receiving a detection halt instruction sent by the mobile terminal 12, the ongoing data acquisition process is halted and the detection-active state is modified to the inactive state.

Optionally, when the active state is detected to be the activated state, the main control module 111 may start the data acquisition process after confirming that the detection object has sent the finger to the designated mechanical part of the device.

In another specific implementation manner provided in this embodiment, the main control module 111 is specifically configured to record, as first acquisition data, acquisition data output by the three-band PPG signal acquisition unit 1131 when it is determined whether the detection object has sent a finger into a mechanical part specified by the device; continuously segmenting the first collected data according to a preset time interval to obtain a plurality of first segmented data; carrying out average light intensity calculation on each first segment data to generate corresponding first segment light intensity data; calculating the difference of the adjacent first subsection light intensity data to generate a corresponding first light intensity difference value which is the light intensity data of the previous first subsection and the light intensity data of the next first subsection; and if the first light intensity difference value is positive and greater than the first set light intensity threshold value, confirming that the detection object sends the finger into the appointed mechanical part of the equipment.

The first subsection light intensity data obtained before the finger is sent to the appointed mechanical part of the equipment by the detection object is definitely larger than the first subsection light intensity data obtained after the finger is sent to the appointed mechanical part of the equipment; continuously comparing all the segments of the first acquired data, and once the light intensity difference of the front segment and the rear segment is found to have obvious change and the change trend is a reduction trend, considering that the change is probably caused by the fact that the finger is sent into a designated mechanical part of the equipment by the detection object; and if the first light intensity difference is larger than the first set light intensity threshold value, determining that the detection object has sent the finger into the appointed mechanical part of the equipment.

Optionally, when the active state is detected to be the activated state, the main control module 111 may further stop the ongoing data acquisition processing after confirming that the detection object has moved the finger away from the mechanical part specified by the device, modify the detected active state to the inactive state, and send acquisition error information to the mobile terminal 12.

In another specific implementation manner provided in this embodiment, the main control module 111 is specifically configured to mark the acquired data output by the three-band PPG signal acquisition unit 1131 as second acquired data when it is determined whether the detected object has moved a finger away from the mechanical part specified by the device; continuously segmenting the second acquired data according to a preset time interval to obtain a plurality of second segmented data; carrying out average light intensity calculation on each second segment data to generate corresponding second segment light intensity data; calculating the difference of the adjacent second segment light intensity data to generate a corresponding second light intensity difference value which is the light intensity data of the previous second segment and the light intensity data of the next second segment; and if the second light intensity difference value is negative and smaller than a second set light intensity threshold value, confirming that the detection object removes the finger from the appointed mechanical part of the equipment.

Here, the second segmented light intensity data obtained before the detection object moves the finger device away from the device-designated mechanical part is definitely smaller than the second segmented light intensity data obtained after the finger device is moved away from the device-designated mechanical part; continuously comparing all the segments of the second acquired data, and once the light intensity difference of the front segment and the rear segment is found to have obvious change and the change trend is an increasing trend, considering that the change is probably caused by the fact that the finger equipment is moved away from the appointed mechanical part of the equipment; and determining that the detection object moves the finger device away from the appointed mechanical part of the device if the second light intensity difference is smaller than a second set light intensity threshold value.

In another specific implementation manner provided in this embodiment, the main control module 111 is specifically configured to send corresponding data acquisition instructions to the three-band PPG signal acquisition unit 1131, the ambient light signal acquisition unit 1132, the body surface thermal radiation acquisition unit 1133, the ambient thermal radiation acquisition unit 1134, the body surface temperature and humidity acquisition unit 1135, the ambient temperature and humidity acquisition unit 1136, and the contact conduction thermal acquisition unit 1137, respectively, when performing data acquisition on the detection object and the detection environment by using the data acquisition module 113; and collecting data returned by each collecting unit are received to form a collected data set.

Here, the main control module 111 starts a data acquisition processing flow for the detection object and the detection environment when the detection activation state is the activation state, specifically, performs data acquisition for the detection object and the detection environment through the data acquisition module 113; when data acquisition is performed, the main control module 111 sends corresponding data acquisition instructions (hereinafter, first, second, third, fourth, fifth, sixth, and seventh data acquisition instructions) to the acquisition units (the three-band PPG signal acquisition unit 1131, the ambient light signal acquisition unit 1132, the body surface thermal radiation acquisition unit 1133, the ambient thermal radiation acquisition unit 1134, the body surface temperature and humidity acquisition unit 1135, the ambient temperature and humidity acquisition unit 1136, and the contact conduction thermal acquisition unit 1137) of the data acquisition module 113, thereby exciting each acquisition unit to perform corresponding data acquisition operation to generate corresponding acquisition data (three groups of PPG signal acquisition data, ambient light signal acquisition data, body surface thermal radiation acquisition data, ambient thermal radiation acquisition data, body surface temperature acquisition data, body surface humidity acquisition data, ambient temperature acquisition data, ambient humidity acquisition data, and contact heat conduction acquisition data) to be sent back to the main control module 111; the main control module 111 integrates all the received collected data according to a specified format to obtain a collected data set, and sends the collected data set to the mobile terminal 12.

In another specific implementation manner provided in this embodiment, the three-band PPG signal acquisition unit 1131 is configured to call three light emitting diodes of the three-band led array when receiving the first data acquisition instruction, and sequentially use light of three bands to perform light emission irradiation on the top of the finger of the detected object; in each irradiation process, converging the light rays transmitted by the abdomen of the finger of the detected object through a first lens positioned on the abdomen of the finger, and carrying out photoelectric conversion on the converged light rays through a first photoelectric detector on the other side of the first lens to generate a group of PPG signal acquisition data of corresponding wave bands; and the three sets of PPG signal acquisition data corresponding to the three bands are combined into three sets of PPG signal acquisition data, which are sent to the main control module 111.

Here, the three leds of the three-band led array in the three-band PPG signal collecting unit 1131 are three infrared leds with light-emitting bands of 650nm, 940nm, and 1050nm, respectively, and the collecting of three groups of PPG signals with different bands is to improve the analysis accuracy of the PPG signals.

In another specific implementation manner provided in this embodiment, the ambient light signal collecting unit 1132 is configured to, when receiving the second data collecting instruction, invoke a second photodetector to perform photoelectric conversion processing on the natural light collected by the second lens, generate ambient light signal collecting data, and send the ambient light signal collecting data to the main control module 111.

In another specific implementation manner provided in this embodiment, the body surface thermal radiation collecting unit 1133 is configured to, when receiving the third data collecting instruction, invoke a first infrared radiation temperature sensor having a first distance from the body surface of the detection object, collect a thermal radiation signal of the body surface of the detection object, and generate the thermal radiation collecting data of the body surface to be sent to the main control module 111.

In another specific implementation manner provided in this embodiment, the environmental thermal radiation acquisition unit 1134 is configured to, when receiving the fourth data acquisition instruction, invoke a second infrared radiation temperature sensor having a second interval distance from the body surface of the detection object, acquire a thermal radiation signal of the detection environment, generate environmental thermal radiation acquisition data, and send the environmental thermal radiation acquisition data to the main control module 111; the second spacing distance is greater than the first spacing distance.

In another specific implementation manner provided in this embodiment, the body surface temperature and humidity acquisition unit 1135 is configured to, when receiving the fifth data acquisition instruction, invoke the first temperature and humidity sensor whose body surface distance from the detection object is smaller than the set proximity threshold, acquire the body surface temperature and humidity change signal of the detection object, generate corresponding body surface temperature acquisition data and body surface humidity acquisition data, and send the corresponding body surface temperature acquisition data and body surface humidity acquisition data to the main control module 111.

In another specific implementation manner provided in this embodiment, the environment temperature and humidity acquisition unit 1136 is configured to, when receiving the sixth data acquisition instruction, invoke a second temperature and humidity sensor whose body surface distance to the detection object is greater than the set close range threshold, acquire a temperature and humidity change signal of the detection environment, generate corresponding environment temperature acquisition data and environment humidity acquisition data, and send the environment temperature acquisition data and the environment humidity acquisition data to the main control module 111.

In another specific implementation manner provided in this embodiment, the contact conduction heat collecting unit 1137 is configured to invoke a thermistor sensor in contact with a body surface of the detection object when receiving the seventh data collecting instruction, collect a contact heat conduction signal of the detection object, generate corresponding contact heat conduction collection data, and send the contact heat conduction collection data to the main control module 111.

(II) Mobile terminal 12

The mobile terminal 12 is connected with the server 13;

the mobile terminal 12 is configured to perform PPG signal display processing on the three groups of PPG signal acquisition data; the mobile terminal 12 is further configured to send the collected data set to the server 13, receive blood glucose analysis data sent back by the server 13, and perform data display processing on the blood glucose analysis data.

Here, the mobile terminal 12 includes a bluetooth communication module and a wireless communication module, and the wireless communication module includes a WIFI communication sub-module and a 4G/5G communication sub-module; the mobile terminal 12 is connected with the data acquisition device 11 through a bluetooth communication module, and is connected with the server 13 through a wireless communication module.

The mobile terminal 12 is further configured to provide a blood glucose detection application program for the test object, and obtain a data acquisition device connection instruction input by the test object through the blood glucose detection application program; when receiving a connection instruction of the data acquisition equipment, sending the connection instruction to the data acquisition equipment 11 through the Bluetooth communication module; and after the connection with the data acquisition device 11 is successful, a corresponding data channel is established locally as a third data receiving and transmitting Bluetooth channel for taking charge of data sending and receiving operations with the data acquisition device 11.

The mobile terminal 12 is further configured to obtain a detection starting instruction input by the detection object through the blood glucose detection application program; when receiving a detection starting instruction, sending a detection instruction to the data acquisition equipment 11 through a third data receiving and sending Bluetooth channel; and after the instruction is successfully sent, receiving the collected data set sent by the data collecting device 11 through a third data receiving and sending bluetooth channel.

The mobile terminal 12 is further configured to obtain a detection stopping instruction input by the detection object through the blood sugar detection application program; and when receiving the detection stopping instruction, sends a detection stopping instruction to the data acquisition device 11 through the third data receiving and transmitting bluetooth channel.

In another specific implementation manner provided in this embodiment, the mobile terminal 12 is specifically configured to extract three groups of PPG signal acquisition data from the acquisition data set to generate corresponding first, second, and third PPG signal data, and extract ambient light signal acquisition data to generate corresponding first natural light signal data, when the PPG signal is displayed and processed; respectively carrying out signal difference calculation on the first PPG signal data, the second PPG signal data and the third PPG signal data according to the first natural light signal data to generate corresponding first difference signal data, second difference signal data and third difference signal data; down-sampling and filtering the first, second and third differential signal data to generate corresponding first, second and third filtered signal data; and dividing a corresponding display area on a terminal display interface to perform continuous waveform display on the first, second and third filtered signal data.

Optionally, the mobile terminal 12 is further configured to count the signal-to-noise ratios of the first, second, and third filtered signal data to generate corresponding first, second, and third signal-to-noise ratios when performing continuous waveform display on the first, second, and third filtered signal data; and when any signal-to-noise ratio does not meet the set normal signal-to-noise ratio range, stopping the ongoing continuous waveform display, and sending a detection stopping instruction to the data acquisition equipment 11.

Optionally, the mobile terminal 12 is further configured to prompt the detection object for the information of the insufficient power of the device when receiving the information of the insufficient power sent by the data acquisition device 11.

Optionally, when receiving the acquisition error information sent by the data acquisition device 11, the mobile terminal 12 prompts the detection object for the acquisition error and the acquisition suspension information.

Optionally, the mobile terminal 12 is further configured to receive the oximetry data and the pulse rate analysis data sent back by the server 13, and perform data display processing on the oximetry data and the pulse rate analysis data.

(III) Server 13

The server 13 is configured to perform blood glucose analysis according to the collected data set to generate blood glucose analysis data, and send the blood glucose analysis data to the mobile terminal 12.

In another specific implementation manner provided in this embodiment, the server 13 is specifically configured to extract three groups of PPG signal acquisition data, ambient light signal acquisition data, body surface thermal radiation acquisition data, ambient thermal radiation acquisition data, body surface temperature acquisition data, body surface humidity acquisition data, ambient temperature acquisition data, ambient humidity acquisition data, and contact thermal conduction acquisition data from the collected data set when performing blood glucose analysis according to the collected data set;

respectively extracting direct current signal characteristics and alternating current signal characteristics of the three groups of PPG signal acquisition data, and performing normalization processing on the extracted characteristics to obtain three groups of PPG characteristic data, wherein each group of PPG characteristic data comprises a pair of direct current characteristic data and alternating current characteristic data;

respectively extracting corresponding characteristic segments of the ambient light signal acquisition data, the body surface thermal radiation acquisition data, the ambient thermal radiation acquisition data, the body surface temperature acquisition data, the body surface humidity acquisition data, the ambient temperature acquisition data, the ambient humidity acquisition data and the contact thermal conduction acquisition data, calculating the signal or data average value of each characteristic segment, carrying out normalization processing on each signal or data average value, and taking the processing result as corresponding ambient light characteristic data, body surface thermal radiation characteristic data, ambient thermal radiation characteristic data, body surface temperature characteristic data, body surface humidity characteristic data, ambient temperature characteristic data, ambient humidity characteristic data and contact thermal conduction characteristic data; according to a preset input vector structure of an artificial intelligence blood sugar analysis model, all the characteristic data are fused into a characteristic vector;

and inputting the characteristic vector into an artificial intelligent blood sugar analysis model for blood sugar analysis, thereby obtaining corresponding blood sugar analysis data.

Here, based on the well-known beer-lambert law, the absorption degree of the solution to the transmitted light is known to be related to the concentration of solute, and further, the higher the concentration of glucose in blood is, the smaller the light intensity transmitted through human tissues is, so that the change of blood glucose can be observed by analyzing PPG characteristic data; based on the Metabolic Heat Conformation (MHC) theory, it is known that the energy rhythm of different periods of time in the human body has a certain correlation with the energy released after metabolism of the human body, and the energy generated by glucose oxidation can be emitted from the human body to the environment in the form of Heat energy, so that the Metabolic Heat of the human body is correlated with the glucose level and the oxygen supply amount, that is, under the condition of ensuring oxygen supply, the blood glucose change can be observed by taking the Metabolic Heat of the human body as a reference based on the Metabolic Heat Conformation theory. The artificial intelligent blood sugar analysis model is realized based on the beer-lambert law and the metabolic heat conformation theory, the neural network structure of the model is similar to a Multilayer Perceptron (MLP), and the output of the model is actually a predicted blood sugar fluctuation value. After obtaining the predicted blood glucose fluctuation value, the server 13 obtains a calibration blood glucose value corresponding to the detection object from a preset calibration database, and obtains final blood glucose analysis data in a calculation manner of the calibration blood glucose value + the blood glucose fluctuation value being blood glucose analysis data. The calibration blood glucose level stored in the calibration database is a measured blood glucose level of the test object obtained by a conventional blood glucose measuring method.

Optionally, the server 13 is further configured to perform, according to the three sets of PPG signal acquisition data and ambient light signal acquisition data in the acquisition data set, oxyhemoglobin saturation analysis to obtain corresponding oxyhemoglobin saturation analysis data, perform frequency analysis of the pulse wave to obtain corresponding pulse rate analysis data, and send the oxyhemoglobin saturation analysis data and the pulse rate analysis data to the mobile terminal 12.

It should be noted that the division of the modules of the above system is only a logical division, and the actual implementation may be wholly or partially integrated into one physical entity, or may be physically separated. And these modules can be realized in the form of software called by processing element; or may be implemented entirely in hardware; and part of the modules can be realized in the form of calling software by the processing element, and part of the modules can be realized in the form of hardware. For example, the obtaining module may be a processing element separately set up, or may be implemented by being integrated in a chip of the system, or may be stored in a memory of the system in the form of program code, and a processing element of the system calls and executes the functions of the determining module. Other modules are implemented similarly. In addition, all or part of the modules can be integrated together or can be independently realized. The processing element described herein may be an integrated circuit having signal processing capabilities. In the implementation process, each processing step or each module of the system can be completed by hardware integrated logic circuits in a processor element or instructions in the form of software.

For example, the above modules may be one or more integrated circuits configured to implement the above system processing steps, such as: one or more Application Specific Integrated Circuits (ASICs), or one or more Digital Signal Processors (DSPs), or one or more Field Programmable Gate Arrays (FPGAs), etc. For another example, when some of the above modules are implemented in the form of a Processing element scheduler code, the Processing element may be a general-purpose processor, such as a Central Processing Unit (CPU) or other processor that can invoke the program code. As another example, these modules may be integrated together and implemented in the form of a System-on-a-chip (SOC).

In the above embodiments, the implementation may be wholly or partially realized by software, hardware, firmware, or any combination thereof. When implemented in software, may be implemented in whole or in part in the form of a computer program product. The computer program product includes one or more computer instructions. When loaded and executed on a computer, cause the processes or functions described in accordance with the embodiments of the invention to occur, in whole or in part. The computer may be a general purpose computer, a special purpose computer, a network of computers, or other programmable device. The computer instructions may be stored on a computer readable storage medium or transmitted from one computer readable storage medium to another computer readable storage medium, for example, the computer instructions may be transmitted from one website, computer, server, or data center to another website, computer, server, or data center via wire (e.g., coaxial cable, fiber optic, Digital Subscriber Line (DSL)) or wireless (e.g., infrared, wireless, bluetooth, microwave, etc.). The computer-readable storage medium can be any available medium that can be accessed by a computer or a data storage device, such as a server, a data center, etc., that includes one or more of the available media. The usable medium may be a magnetic medium (e.g., a floppy disk, a hard disk, a magnetic tape), an optical medium (e.g., a DVD), or a semiconductor medium (e.g., a Solid State Disk (SSD)), etc.

Those of skill would further appreciate that the various illustrative components and algorithm steps described in connection with the embodiments disclosed herein may be implemented as electronic hardware, computer software, or combinations of both, and that the various illustrative components and steps have been described above generally in terms of their functionality in order to clearly illustrate this interchangeability of hardware and software. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the implementation. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present invention.

The steps of a method or algorithm described in connection with the embodiments disclosed herein may be embodied in hardware, a software module executed by a processor, or a combination of the two. A software module may reside in Random Access Memory (RAM), memory, Read Only Memory (ROM), electrically programmable ROM, electrically erasable programmable ROM, registers, hard disk, a removable disk, a CD-ROM, or any other form of storage medium known in the art.

The above-mentioned embodiments are intended to illustrate the objects, technical solutions and advantages of the present invention in further detail, and it should be understood that the above-mentioned embodiments are merely exemplary embodiments of the present invention, and are not intended to limit the scope of the present invention, and any modifications, equivalent substitutions, improvements and the like made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims

1. A non-invasive blood glucose analysis system, the system comprising: the system comprises data acquisition equipment, a mobile terminal and a server;

2. The non-invasive blood glucose analysis system of claim 1,

the main control module is specifically configured to set a preset device state as a starting state when the device self-checking processing is performed on each module; carrying out system parameter self-checking processing on preset system parameters stored in the main control module to generate a first self-checking state; performing signal lamp function self-checking processing on the signal lamp module to generate a second self-checking state; performing self-checking processing on the subunit devices on the data acquisition module to generate a third self-checking state; performing Bluetooth module self-checking processing on the Bluetooth communication module to generate a fourth self-checking state; judging whether the first self-checking state, the second self-checking state, the third self-checking state and the fourth self-checking state are all self-checking success or not; if all the equipment states are in the normal working state, the equipment states are set to be in the normal working state; if the equipment is not completely in the self-checking state, setting the equipment state as a fault state; when the equipment state is a normal working state, setting the display color of the signal lamp module to be a preset first color; and when the equipment state is that the equipment self-checking fails, setting the display color of the signal lamp module to be a preset second color.

3. The non-invasive blood glucose analysis system of claim 1,

the main control module is specifically used for periodically acquiring the residual battery power from the battery management module according to a preset power check frequency when the battery management module is used for managing the power of the equipment; when the residual battery power is not lower than a preset normal working power threshold value, setting the display color of a signal lamp of the signal lamp module to be a preset first color; and when the residual battery power is lower than the normal working power threshold, setting the equipment state to be a power shortage state.

4. The non-invasive blood glucose analysis system of claim 1,

the master control module is specifically used for recording the mobile terminal corresponding to the preset Bluetooth pairing terminal information as a target terminal and scanning the target terminal when the active Bluetooth connection processing is carried out through the Bluetooth communication module; if the target terminal is found by scanning, performing first Bluetooth pairing processing on the target terminal; and if the first Bluetooth pairing processing is successful, establishing a first data receiving and transmitting Bluetooth channel corresponding to the target terminal, and setting the signal lamp display color of the signal lamp module to be a preset third color.

5. The non-invasive blood glucose analysis system of claim 1,

the data acquisition equipment is specifically used for performing second Bluetooth pairing processing with the mobile terminal when the passive Bluetooth connection processing is performed through the Bluetooth communication module; and if the second Bluetooth pairing processing is successful, creating a second data receiving and transmitting Bluetooth channel corresponding to the mobile terminal, and setting the signal lamp display color of the signal lamp module to be a preset third color.

6. The non-invasive blood glucose analysis system of claim 1,

the data acquisition module comprises a three-band PPG signal acquisition unit, an ambient light signal acquisition unit, a body surface thermal radiation acquisition unit, an ambient thermal radiation acquisition unit, a body surface temperature and humidity acquisition unit, an ambient temperature and humidity acquisition unit and a contact conduction heat acquisition unit; each acquisition unit of the data acquisition module is respectively connected with the main control module;

7. The non-invasive blood glucose analysis system of claim 6,

the main control module is specifically configured to send corresponding data acquisition instructions to the three-band PPG signal acquisition unit, the ambient light signal acquisition unit, the body surface thermal radiation acquisition unit, the ambient thermal radiation acquisition unit, the body surface temperature and humidity acquisition unit, the ambient temperature and humidity acquisition unit, and the contact conduction thermal acquisition unit, respectively, when the data acquisition module acquires data of a detection object and a detection environment; and receiving the collected data returned by each collecting unit to form the collected data set.

8. The non-invasive blood glucose analysis system of claim 7,

the three-band PPG signal acquisition unit is used for calling three light emitting diodes of the three-band light emitting diode array when receiving a first data acquisition instruction, and sequentially using the light rays of the three bands to carry out light emitting irradiation on the top of the finger of the detected object; in each irradiation process, converging the transmission light rays of the finger abdomen through the first lens positioned on the finger abdomen of the detection object, and carrying out photoelectric conversion on the converged light rays through the first photoelectric detector on the other side of the first lens to generate a group of PPG signal acquisition data of corresponding wave bands; the three groups of PPG signal acquisition data are formed by the PPG signal acquisition data corresponding to the three wave bands and are sent to the main control module;

9. The non-invasive blood glucose analysis system of claim 6,

the three bands are 650nm infrared band, 940nm near infrared band and 1050nm near infrared band.