CN114388059B - Protein section generation method based on three-dimensional force feedback controller - Google Patents

Protein section generation method based on three-dimensional force feedback controller Download PDF

Info

Publication number
CN114388059B
CN114388059B CN202210039037.XA CN202210039037A CN114388059B CN 114388059 B CN114388059 B CN 114388059B CN 202210039037 A CN202210039037 A CN 202210039037A CN 114388059 B CN114388059 B CN 114388059B
Authority
CN
China
Prior art keywords
force feedback
feedback controller
dimensional
protein
dimensional force
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202210039037.XA
Other languages
Chinese (zh)
Other versions
CN114388059A (en
Inventor
成生辉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Westlake University
Original Assignee
Westlake University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Westlake University filed Critical Westlake University
Priority to CN202210039037.XA priority Critical patent/CN114388059B/en
Publication of CN114388059A publication Critical patent/CN114388059A/en
Application granted granted Critical
Publication of CN114388059B publication Critical patent/CN114388059B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G16B15/20Protein or domain folding
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T17/00Three dimensional [3D] modelling, e.g. data description of 3D objects

Abstract

The invention discloses a method, a device, equipment and a computer readable storage medium for generating a protein section based on a three-dimensional force feedback controller, wherein the method for generating the protein section based on the three-dimensional force feedback controller comprises the following steps: establishing a three-dimensional space in a terminal, and loading a three-dimensional image of a protein to be observed in the three-dimensional space; mapping the three-dimensional space to a display module connected with the terminal in real time; connecting a three-dimensional force feedback controller with the terminal, and establishing a reference plane in the three-dimensional space according to the three-dimensional force feedback controller; controlling the reference surface to move in the three-dimensional space according to the three-dimensional force feedback controller; and after receiving the confirmation instruction, generating a cross-sectional view of the protein to be observed by taking the datum plane as a reference. The method has the advantage of simplifying the protein cross-section generation mode.

Description

Protein section generation method based on three-dimensional force feedback controller
Technical Field
The invention relates to the technical field of protein section generation, in particular to a protein section generation method, device and equipment based on a three-dimensional force feedback controller and a computer readable storage medium.
Background
The spatial structure body of protein formed by stacking polypeptide chains in a spatially disordered manner is widely used in the computer three-dimensional imaging technology of protein in order to understand the microstructure thereof.
However, attention is paid to the arrangement of basic amino acid functional units, and there is no clear knowledge of the dense distribution of the protein interior and the porosity.
In order to intuitively show the conditions of dense distribution, porosity and the like in the protein, it is common practice to perform a boolean subtraction operation on the protein with a virtual plane on a computer, so as to obtain a corresponding sectional view. The cross section operation needs to select a plurality of references and set a plurality of parameters, so that the operation is complex, and the professional ability of a user is high.
Disclosure of Invention
The embodiment of the application aims to simplify the section generation mode of the protein by providing the protein section generation method based on the three-dimensional force feedback controller.
In order to achieve the above objective, an embodiment of the present application provides a method for generating a protein cross section based on a three-dimensional force feedback controller, including:
establishing a three-dimensional space in a terminal, and loading a three-dimensional image of a protein to be observed in the three-dimensional space;
mapping the three-dimensional space to a display module connected with the terminal in real time;
connecting a three-dimensional force feedback controller with the terminal, and establishing a reference plane in the three-dimensional space according to the three-dimensional force feedback controller;
controlling the reference surface to move in the three-dimensional space according to the three-dimensional force feedback controller;
and after receiving the confirmation instruction, generating a cross-sectional view of the protein to be observed by taking the datum plane as a reference.
In one embodiment, the three-dimensional force feedback controller comprises a manipulation pen;
generating a reference plane in the three-dimensional space according to the three-dimensional force feedback controller, including:
and generating the reference surface by taking the pen point of the control pen as a plane center and taking the extending direction of the control pen as a plane normal.
In an embodiment, controlling the reference plane to move in the three-dimensional space according to the three-dimensional force feedback controller includes:
and controlling the movement and the angle of the reference surface in the three-dimensional space according to the movement parameters of the pen point of the control pen and the change of the extending direction of the control pen.
In an embodiment, before generating the reference surface in the three-dimensional space according to the three-dimensional force feedback controller, the method further comprises:
and mapping the pen point of the control pen to a preset original point of the three-dimensional space.
In one embodiment, generating the cross-sectional view of the protein to be observed with reference to the datum plane includes:
taking the intersection surface of the reference surface and the three-dimensional image as a cross section position, and performing Boolean subtraction on the three-dimensional image of the protein to be observed to generate a cross section diagram of the protein to be observed;
and displaying the cross-sectional view through the display module.
In an embodiment, the method further comprises:
and when the reference surface is contacted with the three-dimensional image of the protein to be observed, controlling the control pen of the three-dimensional force feedback controller to provide vibration feedback.
In one embodiment, the confirmation instruction is derived from a preset foot switch or a manual switch.
In order to achieve the above objective, an embodiment of the present application further provides a protein cross section generating device based on a three-dimensional force feedback controller, including:
the terminal is used for establishing a three-dimensional space and loading a three-dimensional image of the protein to be observed;
the display module is connected with the terminal and used for displaying the three-dimensional space in real time;
the three-dimensional force feedback controller is connected with the terminal and is used for establishing a reference plane in the three-dimensional space and controlling the reference plane to move in the three-dimensional space;
and the confirmation module is used for sending a confirmation instruction to the terminal so that the terminal can generate the cross-sectional view of the protein to be observed by taking the datum plane as a reference.
To achieve the above objective, an embodiment of the present application further provides a three-dimensional force feedback controller-based protein cross section generating device, which includes a memory, a processor, and a three-dimensional force feedback controller-based protein cross section generating program stored in the memory and capable of running on the processor, where the processor implements the three-dimensional force feedback controller-based protein cross section generating method according to any one of the above when executing the three-dimensional force feedback controller-based protein cross section generating program.
To achieve the above object, an embodiment of the present application further provides a computer readable storage medium, where a protein cross section generating program based on a three-dimensional force feedback controller is stored, where the protein cross section generating program based on the three-dimensional force feedback controller implements the protein cross section generating method based on the three-dimensional force feedback controller according to any one of the above embodiments when executed by a processor.
According to the protein cross section generation method based on the three-dimensional force feedback controller, the three-dimensional force feedback controller is used for establishing the reference surface in the three-dimensional space, then the reference surface is controlled to freely move in the three-dimensional space based on the three-dimensional force feedback controller, and finally the reference surface is used as a reference to generate a cross section of protein to be observed, so that any required protein cross section can be generated without inputting complex parameters, and the technical difficulty of acquiring the protein cross section is reduced; and moreover, the mode of moving the reference surface through the three-dimensional force feedback controller is visual and convenient, accords with the intuition of operation of a user, and has low use threshold. Therefore, compared with the traditional method for generating the protein cross-sectional diagram by setting complex parameters, the method has the advantages of convenience in operation and low use threshold.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and other drawings may be obtained according to the structures shown in these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a block diagram of one embodiment of a three-dimensional force feedback controller-based protein cross section generating apparatus of the present invention;
FIG. 2 is a schematic flow chart of an embodiment of a method for generating a protein cross section based on a three-dimensional force feedback controller according to the present invention;
FIG. 3 is a block diagram illustrating an embodiment of a three-dimensional force feedback controller-based protein cross section generating apparatus according to the present invention.
The achievement of the objects, functional features and advantages of the present invention will be further described with reference to the accompanying drawings, in conjunction with the embodiments.
Detailed Description
It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the invention.
In order that the above-described aspects may be better understood, exemplary embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. While exemplary embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure may be embodied in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art.
It should be noted that in the claims, any reference signs placed between parentheses shall not be construed as limiting the claim. The word "comprising" does not exclude the presence of elements or steps other than those listed in a claim. The word "a" or "an" preceding an element does not exclude the presence of a plurality of such elements. The invention may be implemented by means of hardware comprising several distinct elements, and by means of a suitably programmed computer. In the unit claims enumerating several means, several of these means may be embodied by one and the same item of hardware. And the use of "first," "second," and "third," etc. do not denote any order, and the terms may be construed as names.
As shown in fig. 1, fig. 1 is a schematic structural diagram of a server 1 (also called a protein cross section generating device based on a three-dimensional force feedback controller) of a hardware running environment according to an embodiment of the present invention.
The server provided by the embodiment of the invention is equipment with a display function, such as 'Internet of things equipment', AR/VR equipment with a networking function, a PC, a smart phone, a tablet personal computer, a portable computer and the like.
As shown in fig. 1, the server 1 includes: memory 11, processor 12 and network interface 13.
The memory 11 includes at least one type of readable storage medium including flash memory, a hard disk, a multimedia card, a card memory (e.g., SD or DX memory, etc.), a magnetic memory, a magnetic disk, an optical disk, etc. The memory 11 may in some embodiments be an internal storage unit of the server 1, such as a hard disk of the server 1. The memory 11 may in other embodiments also be an external storage device of the server 1, such as a plug-in hard disk, a Smart Media Card (SMC), a Secure Digital (SD) Card, a Flash Card (Flash Card) or the like, which are provided on the server 1.
Further, the memory 11 may also include an internal storage unit of the server 1 as well as an external storage device. The memory 11 may be used not only for storing application software installed in the server 1 and various types of data, such as codes of the three-dimensional force feedback controller-based protein cross section generating program 10, but also for temporarily storing data that has been output or is to be output.
Processor 12 may in some embodiments be a central processing unit (Central Processing Unit, CPU), controller, microcontroller, microprocessor or other data processing chip for running program code or processing data stored in memory 11, for example, executing a three-dimensional force feedback controller based protein cross section generating program 10 or the like.
The network interface 13 may optionally comprise a standard wired interface, a wireless interface (e.g. WI-FI interface), typically used to establish a communication connection between the server 1 and other electronic devices.
The network may be the internet, a cloud network, a wireless fidelity (Wi-Fi) network, a Personal Area Network (PAN), a Local Area Network (LAN), and/or a Metropolitan Area Network (MAN). Various devices in a network environment may be configured to connect to a communication network according to various wired and wireless communication protocols. Examples of such wired and wireless communication protocols may include, but are not limited to, at least one of the following: transmission control protocol and internet protocol (TCP/IP), user Datagram Protocol (UDP), hypertext transfer protocol (HTTP), file Transfer Protocol (FTP), zigBee, EDGE, IEEE 802.11, light fidelity (Li-Fi), 802.16, IEEE 802.11s, IEEE 802.11g, multi-hop communications, wireless Access Points (APs), device-to-device communications, cellular communication protocol and/or bluetooth (bluetooth) communication protocol, or combinations thereof.
Optionally, the server may further comprise a user interface, which may comprise a Display (Display), an input unit such as a Keyboard (Keyboard), and optionally a standard wired interface, a wireless interface. Alternatively, in some embodiments, the display may be an LED display, a liquid crystal display, a touch-sensitive liquid crystal display, an OLED (Organic Light-Emitting Diode) touch, or the like. The display may also be referred to as a display screen or a display unit, for displaying information processed in the server 1 and for displaying a visual user interface.
Fig. 1 shows only a server 1 with components 11-13 and a three-dimensional force feedback controller based protein cross section generating program 10, it will be understood by those skilled in the art that the structure shown in fig. 1 does not constitute a limitation of the server 1, and may include fewer or more components than shown, or may combine certain components, or a different arrangement of components.
In this embodiment, the processor 12 may be configured to call a protein cross-section generating program based on a three-dimensional force feedback controller stored in the memory 11, and perform the following operations:
establishing a three-dimensional space in a terminal, and loading a three-dimensional image of a protein to be observed in the three-dimensional space;
mapping the three-dimensional space to a display module connected with the terminal in real time;
connecting a three-dimensional force feedback controller with the terminal, and establishing a reference plane in the three-dimensional space according to the three-dimensional force feedback controller;
controlling the reference surface to move in the three-dimensional space according to the three-dimensional force feedback controller;
and after receiving the confirmation instruction, generating a cross-sectional view of the protein to be observed by taking the datum plane as a reference.
In one embodiment, the processor 12 may be configured to invoke the three-dimensional force feedback controller-based protein cross-section generation program stored in the memory 11, and perform the following operations:
generating a reference plane in the three-dimensional space according to the three-dimensional force feedback controller, including:
and generating the reference surface by taking the pen point of the control pen as a plane center and taking the extending direction of the control pen as a plane normal.
In one embodiment, the processor 12 may be configured to invoke the three-dimensional force feedback controller-based protein cross-section generation program stored in the memory 11, and perform the following operations:
and controlling the movement and the angle of the reference surface in the three-dimensional space according to the movement parameters of the pen point of the control pen and the change of the extending direction of the control pen.
In one embodiment, the processor 12 may be configured to invoke the three-dimensional force feedback controller-based protein cross-section generation program stored in the memory 11, and perform the following operations:
and mapping the pen point of the control pen to a preset original point of the three-dimensional space.
In one embodiment, the processor 12 may be configured to invoke the three-dimensional force feedback controller-based protein cross-section generation program stored in the memory 11, and perform the following operations:
taking the intersection surface of the reference surface and the three-dimensional image as a cross section position, and performing Boolean subtraction on the three-dimensional image of the protein to be observed to generate a cross section diagram of the protein to be observed;
and displaying the cross-sectional view through the display module.
In one embodiment, the processor 12 may be configured to invoke the three-dimensional force feedback controller-based protein cross-section generation program stored in the memory 11, and perform the following operations:
and when the reference surface is contacted with the three-dimensional image of the protein to be observed, controlling the control pen of the three-dimensional force feedback controller to provide vibration feedback.
In one embodiment, the processor 12 may be configured to invoke the three-dimensional force feedback controller-based protein cross-section generation program stored in the memory 11, and perform the following operations:
the confirmation instruction is from a preset foot control switch or a manual control switch.
Based on the hardware framework of the protein section generating device based on the three-dimensional force feedback controller, the embodiment of the protein section generating method based on the three-dimensional force feedback controller is provided. The invention discloses a protein section generation method based on a three-dimensional force feedback controller, which aims to simplify a section generation mode of protein.
Referring to fig. 2, fig. 2 is an embodiment of a three-dimensional force feedback controller-based protein cross section generating method according to the present invention, the three-dimensional force feedback controller-based protein cross section generating method includes the following steps:
s10, establishing a three-dimensional space in the terminal, and loading a three-dimensional image of the protein to be observed in the three-dimensional space.
The terminal may be a local computing device, such as a PC, a portable computer, a tablet computer, a local server, or a cloud computing device, such as a cloud server.
In particular, the desired three-dimensional space may be established by enabling a specific three-dimensional program, such as UG, solidWorks, 3Dmax, blender, etc., on the terminal. After the establishment of the three-dimensional space is completed, loading the data of the protein to be observed, and generating a three-dimensional image of the corresponding protein in the three-dimensional space. The three-dimensional image is capable of sufficiently exhibiting the stereoscopic shape of the protein to be observed.
And S20, mapping the three-dimensional space to a display module connected with the terminal in real time.
The display module may be a display screen integrated by the terminal itself, or an external display, a projector, or the like connected to the terminal.
Specifically, after the three-dimensional image of the protein to be observed is loaded into the three-dimensional space, the content of the three-dimensional space can be displayed in real time through the display module, so that a user can more intuitively observe the shape and structure of the protein to be observed in the three-dimensional space, and the position of the reference surface in the three-dimensional space can be conveniently and intuitively adjusted by the user.
And S30, connecting a three-dimensional force feedback controller with the terminal, and establishing a reference plane in the three-dimensional space according to the three-dimensional force feedback controller.
The three-dimensional force feedback controller is a controller which can perform three-dimensional control on a target and has tactile feedback.
Specifically, after the three-dimensional force feedback controller is connected to the terminal, a reference plane may be established in a three-dimensional space of the terminal based on the three-dimensional force feedback controller, and the reference plane may be movable in the three-dimensional space.
And S40, controlling the reference surface to move in the three-dimensional space according to the three-dimensional force feedback controller.
Specifically, the three-dimensional force feedback controller has a function of controlling the movement of the target object in the three-dimensional space, and therefore, the reference surface can be taken as the controlled object to control the movement of the reference surface in the three-dimensional space by the three-dimensional force feedback controller.
S50, after receiving the confirmation instruction, generating a cross-sectional view of the protein to be observed by taking the datum plane as a reference.
Specifically, when the reference plane is moved in the three-dimensional space, if the reference plane is moved to the section position required by any user, a confirmation instruction can be sent to the terminal, and after the terminal receives the corresponding confirmation instruction, the interface between the reference plane and the three-dimensional image can be taken as the section, so that a section view of the protein to be observed can be generated.
It can be understood that according to the protein cross section generation method based on the three-dimensional force feedback controller, the three-dimensional force feedback controller is used for establishing a reference plane in a three-dimensional space, then the reference plane is controlled to freely move in the three-dimensional space based on the three-dimensional force feedback controller, and finally the reference plane is used as a reference for generating a cross section of protein to be observed, so that any required protein cross section can be generated without inputting complex parameters, and the technical difficulty of acquiring the protein cross section is reduced; and moreover, the mode of moving the reference surface through the three-dimensional force feedback controller is visual and convenient, accords with the intuition of operation of a user, and has low use threshold. Therefore, compared with the traditional method for generating the protein cross-sectional diagram by setting complex parameters, the method has the advantages of convenience in operation and low use threshold.
In one embodiment, a three-dimensional force feedback controller as used herein includes a stylus. The control pen is used for realizing movement control of the reference surface, and particularly, when in actual use, a user can correspondingly realize movement/swing of the reference surface in a three-dimensional space through the movement/swing control pen. Of course, the design of the present application is not limited thereto, and in other embodiments, the three-dimensional force feedback controller may also include a control body such as a rocker.
On the basis that the three-dimensional force feedback controller comprises a manipulation pen, in an embodiment, generating a reference plane in the three-dimensional space according to the three-dimensional force feedback controller comprises:
and generating the reference surface by taking the pen point of the control pen as a plane center and taking the extending direction of the control pen as a plane normal.
Specifically, the moving direction of the reference plane in the three-dimensional space can be determined by taking the pen point of the control pen as the center, and the angle of the reference plane in the three-dimensional space can be determined by taking the extending direction of the control pen as the normal line, so that an accurate reference plane can be generated in the three-dimensional space, and the moving direction and the angle of the reference plane can be accurately controlled. In addition, the extending direction of the control pen is used as the normal of the reference surface, and the angle of the reference surface in the three-dimensional space can be adjusted by adjusting the angle of the control pen. After combining the conditions in the three-dimensional space displayed on the display module in real time, the convenience of user operation can be greatly improved, and the use threshold can be reduced.
In an embodiment, controlling the reference plane to move in the three-dimensional space according to the three-dimensional force feedback controller includes:
and controlling the movement and the angle of the reference surface in the three-dimensional space according to the movement parameters of the pen point of the control pen and the change of the extending direction of the control pen.
Specifically, the moving parameters of the pen nib include a moving direction and a moving distance of the pen nib. After the moving direction and the moving distance of the pen point are obtained, the center point of the reference surface can be correspondingly controlled to correspondingly move in the three-dimensional space, and then the reference surface can be controlled to move in the three-dimensional space. In addition, the angle of the reference surface can be correspondingly adjusted by acquiring the change of the extending direction of the reference control pen.
In an embodiment, before generating the reference surface in the three-dimensional space according to the three-dimensional force feedback controller, the method further comprises:
and mapping the pen point of the control pen to a preset original point of the three-dimensional space.
Specifically, after the three-dimensional force feedback controller is connected with the terminal, the pen point of the stylus can be mapped to a preset origin in the three-dimensional space, so that the reference surface can move in any direction for any distance, and the preset origin is taken as a reference.
It can be understood that before the reference plane is generated, the nib of the control pen is mapped to the preset origin in the three-dimensional space, so that the uniformity of each operation can be ensured, and further, the increase of the operation complexity caused by the position deviation of the reference plane can be avoided, so that the operation difficulty of a user is reduced. In addition, the arrangement can reduce the calculation amount required by the terminal to calculate the moving direction and the moving distance of the reference surface, namely, the terminal load can be reduced.
In one embodiment, generating the cross-sectional view of the protein to be observed with reference to the datum plane includes:
s110, taking the intersection surface of the reference surface and the three-dimensional image as a cross-section position, and performing Boolean subtraction on the three-dimensional image of the protein to be observed to generate a cross-section diagram of the protein to be observed.
Among these, the boolean subtraction operation is the bool subtraction operation. Specifically, when a protein cross section is generated, the cross section of the protein to be observed at the current position can be obtained by performing Boolean subtraction on the three-dimensional image of the protein to be observed by taking the intersection surface of the current reference surface and the three-dimensional image of the protein to be observed as the cross section position.
And S120, displaying the sectional view through the display module.
Specifically, after the cross-sectional view of the protein to be observed is generated, the cross-sectional view may be displayed by the display module, so that the user may observe the truncated cross-sectional view of the protein in real time. The user may then determine whether to reacquire a new protein profile based on the current protein profile.
In an embodiment, the method further comprises:
and when the reference surface is contacted with the three-dimensional image of the protein to be observed, controlling the control pen of the three-dimensional force feedback controller to provide vibration feedback.
Specifically, when the boundary coordinates of the reference surface and the boundary coordinates of the three-dimensional image of the protein to be observed are intersected, the reference surface can be considered to be in contact with the three-dimensional image of the protein to be observed, and at the moment, a feedback instruction can be sent to the three-dimensional force feedback controller so that a control pen of the three-dimensional force feedback controller vibrates, and a user is prompted that the reference surface is in contact with the protein to be observed.
It can be appreciated that the user can be intuitively prompted in this way, so that the user can improve the operation accuracy and acquire the required protein section.
In one embodiment, the confirmation instruction is derived from a preset foot switch or a manual switch.
It can be appreciated that by inputting a confirmation instruction through the foot control switch, both hands of the user can be liberated when the user moves the reference surface, so as to improve the operation efficiency. The manual switch can be integrated on the control pen to facilitate the operation of the user when the confirmation instruction is input through the manual switch.
In addition, referring to fig. 3, an embodiment of the present invention further provides a protein cross section generating device based on a three-dimensional force feedback controller, where the protein cross section generating device based on the three-dimensional force feedback controller includes:
a terminal 110 for creating a three-dimensional space and loading a three-dimensional image of a protein to be observed;
the display module 120 is connected with the terminal and is used for displaying the three-dimensional space in real time;
a three-dimensional force feedback controller 130 connected to the terminal, the three-dimensional force feedback controller being configured to establish a reference plane in the three-dimensional space and control the reference plane to move in the three-dimensional space;
and the confirmation module 140 is used for sending a confirmation instruction to the terminal so that the terminal can generate the cross-sectional view of the protein to be observed by taking the datum plane as a reference.
The steps implemented by each functional module of the three-dimensional force feedback controller-based protein section generating device may refer to each embodiment of the three-dimensional force feedback controller-based protein section generating method according to the present invention, and will not be described herein.
In addition, the embodiment of the invention also provides a computer readable storage medium, which can be any one or any combination of a plurality of hard disk, a multimedia card, an SD card, a flash memory card, an SMC, a read-only memory (ROM), an erasable programmable read-only memory (EPROM), a portable compact disc read-only memory (CD-ROM), a USB memory and the like. The computer readable storage medium includes the protein cross section generating program 10 based on the three-dimensional force feedback controller, and the specific embodiment of the computer readable storage medium of the present invention is substantially the same as the above-mentioned protein cross section generating method based on the three-dimensional force feedback controller and the specific embodiment of the server 1, and will not be described herein.
It will be appreciated by those skilled in the art that embodiments of the present invention may be provided as a method, system, or computer program product. Accordingly, the present invention may take the form of an entirely hardware embodiment, an entirely software embodiment or an embodiment combining software and hardware aspects. Furthermore, the present invention may take the form of a computer program product embodied on one or more computer-usable storage media (including, but not limited to, disk storage, CD-ROM, optical storage, and the like) having computer-usable program code embodied therein.
The present invention is described with reference to flowchart illustrations and/or block diagrams of methods, apparatus (systems) and computer program products according to embodiments of the invention. It will be understood that each flow and/or block of the flowchart illustrations and/or block diagrams, and combinations of flows and/or blocks in the flowchart illustrations and/or block diagrams, can be implemented by computer program instructions. These computer program instructions may be provided to a processor of a general purpose computer, special purpose computer, embedded processor, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, create means for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.
These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including instruction means which implement the function specified in the flowchart flow or flows and/or block diagram block or blocks.
These computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.
While preferred embodiments of the present invention have been described, additional variations and modifications in those embodiments may occur to those skilled in the art once they learn of the basic inventive concepts. It is therefore intended that the following claims be interpreted as including the preferred embodiments and all such alterations and modifications as fall within the scope of the invention.
It will be apparent to those skilled in the art that various modifications and variations can be made to the present invention without departing from the spirit or scope of the invention. Thus, it is intended that the present invention also include such modifications and alterations insofar as they come within the scope of the appended claims or the equivalents thereof.

Claims (8)

1. A protein section generation method based on a three-dimensional force feedback controller is characterized by comprising the following steps:
establishing a three-dimensional space in a terminal, and loading a three-dimensional image of a protein to be observed in the three-dimensional space;
mapping the three-dimensional space to a display module connected with the terminal in real time;
connecting a three-dimensional force feedback controller with the terminal, and establishing a reference plane in the three-dimensional space according to the three-dimensional force feedback controller;
controlling the reference surface to move in the three-dimensional space according to the three-dimensional force feedback controller;
after receiving the confirmation instruction, taking the datum plane as a reference to generate a section view of the protein to be observed, wherein,
the three-dimensional force feedback controller comprises a control pen;
generating a reference plane in the three-dimensional space according to the three-dimensional force feedback controller, including:
the nib of the control pen is taken as a plane center, and the extending direction of the control pen is taken as a plane normal line to generate the reference surface;
controlling the reference plane to move in the three-dimensional space according to the three-dimensional force feedback controller, including:
and controlling the movement and the angle of the reference surface in the three-dimensional space according to the movement parameters of the pen point of the control pen and the change of the extending direction of the control pen.
2. The three-dimensional force feedback controller-based protein cross-section generating method according to claim 1, wherein before generating a reference plane in the three-dimensional space from the three-dimensional force feedback controller, the method further comprises:
and mapping the pen point of the control pen to a preset original point of the three-dimensional space.
3. The method for generating a protein cross section based on a three-dimensional force feedback controller according to claim 1, wherein generating a cross section of the protein to be observed with the reference surface as a reference comprises:
taking the intersection surface of the reference surface and the three-dimensional image as a cross section position, and performing Boolean subtraction on the three-dimensional image of the protein to be observed to generate a cross section diagram of the protein to be observed;
and displaying the cross-sectional view through the display module.
4. The three-dimensional force feedback controller-based protein cross-section generating method of claim 1, further comprising:
and when the reference surface is contacted with the three-dimensional image of the protein to be observed, controlling the control pen of the three-dimensional force feedback controller to provide vibration feedback.
5. The method for generating a protein cross section based on a three-dimensional force feedback controller according to claim 1, wherein,
the confirmation instruction is from a preset foot control switch or a manual control switch.
6. A three-dimensional force feedback controller-based protein cross section generating device, comprising:
the terminal is used for establishing a three-dimensional space and loading a three-dimensional image of the protein to be observed;
the display module is connected with the terminal and used for displaying the three-dimensional space in real time;
the three-dimensional force feedback controller is connected with the terminal and is used for establishing a reference plane in the three-dimensional space and controlling the reference plane to move in the three-dimensional space;
the confirmation module is used for sending a confirmation instruction to the terminal so that the terminal can generate a cross-sectional view of the protein to be observed by taking the datum plane as a reference; wherein, the liquid crystal display device comprises a liquid crystal display device,
the three-dimensional force feedback controller comprises a control pen;
the three-dimensional force feedback controller establishing a reference plane in the three-dimensional space includes: the nib of the control pen is taken as a plane center, and the extending direction of the control pen is taken as a plane normal line to generate the reference surface;
the three-dimensional force feedback controller controlling the reference plane to move in the three-dimensional space comprises: and controlling the movement and the angle of the reference surface in the three-dimensional space according to the movement parameters of the pen point of the control pen and the change of the extending direction of the control pen.
7. A three-dimensional force feedback controller-based protein cross section generating apparatus comprising a memory, a processor and a three-dimensional force feedback controller-based protein cross section generating program stored on the memory and executable on the processor, wherein the three-dimensional force feedback controller-based protein cross section generating program is executed by the processor to implement the three-dimensional force feedback controller-based protein cross section generating method according to any one of claims 1 to 5.
8. A computer-readable storage medium, wherein a protein cross section generating program based on a three-dimensional force feedback controller is stored on the computer-readable storage medium, and when the protein cross section generating program based on the three-dimensional force feedback controller is executed by a processor, the protein cross section generating method based on the three-dimensional force feedback controller according to any one of claims 1 to 5 is realized.
CN202210039037.XA 2022-01-13 2022-01-13 Protein section generation method based on three-dimensional force feedback controller Active CN114388059B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210039037.XA CN114388059B (en) 2022-01-13 2022-01-13 Protein section generation method based on three-dimensional force feedback controller

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210039037.XA CN114388059B (en) 2022-01-13 2022-01-13 Protein section generation method based on three-dimensional force feedback controller

Publications (2)

Publication Number Publication Date
CN114388059A CN114388059A (en) 2022-04-22
CN114388059B true CN114388059B (en) 2023-06-16

Family

ID=81201818

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210039037.XA Active CN114388059B (en) 2022-01-13 2022-01-13 Protein section generation method based on three-dimensional force feedback controller

Country Status (1)

Country Link
CN (1) CN114388059B (en)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2836991A1 (en) * 2012-04-13 2015-02-18 Thomson Licensing Method to render global 6 dof motion effect with multiple local force-feedback
US20160147304A1 (en) * 2014-11-24 2016-05-26 General Electric Company Haptic feedback on the density of virtual 3d objects
US10620721B2 (en) * 2018-01-29 2020-04-14 Google Llc Position-based location indication and device control
CN109116992B (en) * 2018-08-31 2020-12-04 北京航空航天大学 Collision response system for virtual hand force feedback interaction
CN111862333A (en) * 2019-04-28 2020-10-30 广东虚拟现实科技有限公司 Content processing method and device based on augmented reality, terminal equipment and storage medium
JP7335335B2 (en) * 2019-06-28 2023-08-29 富士フイルム株式会社 Information processing device, information processing method, and program
CN112233731B (en) * 2020-10-19 2023-10-10 中山大学 Atomic structure three-dimensional display method, system, storage medium, program, and terminal

Also Published As

Publication number Publication date
CN114388059A (en) 2022-04-22

Similar Documents

Publication Publication Date Title
CN106575354B (en) Virtualization of tangible interface objects
US10909768B2 (en) Virtual item simulation using detected surfaces
WO2016188318A1 (en) 3d human face reconstruction method, apparatus and server
WO2016110199A1 (en) Expression migration method, electronic device and system
KR20140130675A (en) Image processing device, and computer program product
US8838276B1 (en) Methods and systems for providing functionality of an interface to control orientations of a camera on a device
CN111771180A (en) Hybrid placement of objects in augmented reality environment
CN114786786A (en) Bone tracking using previous frames
US11934628B2 (en) 3D user interface depth forgiveness
JP2018504153A (en) Multi-user sensor-based interaction
US10776979B2 (en) Virtual skeleton based on computing device capability profile
US20220383599A1 (en) Method and electronic device for arranging ar object
CN109815557B (en) Robot model display method and device and intelligent terminal
KR101638550B1 (en) Virtual Reality System using of Mixed reality, and thereof implementation method
CN114388059B (en) Protein section generation method based on three-dimensional force feedback controller
CN114388060B (en) Round controller-based protein spherical section generation method
CN114388056B (en) AR-based protein section generation method
CN114388058A (en) Protein arbitrary section generation method based on nine-axis IMU
CN114388055B (en) Protein section generation method based on brain infrared control
US20230419530A1 (en) Augmented reality image reproduction assistant
US20230418062A1 (en) Color calibration tool for see-through augmented reality environment
CN114385010A (en) Protein section generation method based on brain wave control
CN116271830B (en) Behavior control method, device, equipment and storage medium for virtual game object
CN113467602B (en) VR display method and system
CN115445201A (en) Skating motion sensing game method and device and computer readable storage medium

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant