CN114384258A - Sample analyzer and sample analysis method thereof - Google Patents

Sample analyzer and sample analysis method thereof Download PDF

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Publication number
CN114384258A
CN114384258A CN202011111130.4A CN202011111130A CN114384258A CN 114384258 A CN114384258 A CN 114384258A CN 202011111130 A CN202011111130 A CN 202011111130A CN 114384258 A CN114384258 A CN 114384258A
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CN
China
Prior art keywords
sample
sample container
scanning
container
hole site
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Pending
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CN202011111130.4A
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Chinese (zh)
Inventor
陈海云
朱景国
张军伟
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Priority to CN202011111130.4A priority Critical patent/CN114384258A/en
Publication of CN114384258A publication Critical patent/CN114384258A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00871Communications between instruments or with remote terminals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0474Details of actuating means for conveyors or pipettes
    • G01N2035/0491Position sensing, encoding; closed-loop control

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The application relates to a sample analyzer and a sample analyzing method thereof, wherein the sample analyzer comprises a closed sample feeding bin which is provided with a sample accommodating part, a sample feeding transfer part, an active rotating part and a sample scanning part; the sample accommodating part is provided with a first hole position of a first sample container for accommodating a first sample and a second hole position of a second sample container for accommodating a second sample; the sample injection transfer component is used for moving the sample container to enable the hole position to reach the scanning position and the sampling position; the active rotating part is used for driving the sample container arranged in the first hole site or the second hole site on the sample containing part to rotate; the sample scanning component is used for carrying out label scanning on the sample container and acquiring sample information of the first sample or the second sample. The sample analyzer and the sample analysis method thereof avoid the situations of increased operation difficulty, low efficiency and misplacement of samples after manual scanning caused by manual participation in scanning, and can effectively reduce the risk of sample introduction errors.

Description

Sample analyzer and sample analysis method thereof
Technical Field
The invention relates to the technical field of blood sample analysis, in particular to a sample analyzer and a sample analysis method thereof.
Background
Currently, the sample feeding modes of the blood sample analyzer in the market for sample measurement are generally divided into three types: (1) an automatic sample feeding mode, namely a sample feeding mode for placing a plurality of sample containers on a sample rack to continuously measure a plurality of samples; (2) an open sample introduction mode, namely a sample feeding mode for carrying out single sample measurement from a sample container which is opened by hand to a sample suction device; (3) and the closed sample feeding mode is a sample feeding mode that the instrument provides a sample container rack and puts a single sample container into the sample container rack, and then the instrument automatically controls the sample sucker to carry out single sample measurement of sample suction. The latter two sampling methods are commonly used for measurement of emergency samples, peripheral blood samples and pre-diluted samples.
For example, a sample container rack is provided, which is provided with a plurality of insertion holes having different apertures and different depths for fixing sample containers, and the sample container rack can rotate around a designated axis; when the sample is to be measured, a user rotates the sample container holder, rotates the insertion hole corresponding to the outer diameter, length or shape of the sample container to a certain position, puts the sample container in the insertion hole, moves the sample sucker to the position of the sample container, and sucks the sample in the sample container. For another example, a plurality of sample container holders are provided for respectively fixing a plurality of sample containers, each sample container holder having a different aperture or depth; when a sample is to be measured, a user selects a sample container rack which is adaptive to the outer diameter, length or shape of a sample container to be measured and places the sample container rack at a specific position of the instrument, then places the sample container into the sample container rack, and then moves the sample sucker to a sample container placing position and sucks a sample in the sample container.
The existing blood sample analyzer has some defects in sample introduction function. The arranged sample container rack is matched with a plurality of sample containers, so that the risks of easy loss of samples and wrong sample racks exist; in addition, manual sample feeding and sucking processes are needed, the automation degree is low, and the detection speed of the sample is slowed down. In addition, the sampling process lacks the bar code recognition function, and operating personnel need hand-held bar code scanner or manual input bar code before putting into the sample fixer, has increased the degree of difficulty of operation, scans in the analysis appearance outside simultaneously, has the inconsistent risk of sample and the built-in sample of scanning, and manual input has the risk of defeated wrong bar code.
Disclosure of Invention
The invention mainly solves the technical problems that: how to reduce the risk of the wrong sample introduction of the existing sample analyzer. In order to solve the technical problem, the application provides a sample analyzer and a sample analyzing method thereof.
According to a first aspect, an embodiment provides a sample analyzer, which includes a closed sample feeding chamber and a sampling mechanism, wherein a sample accommodating part, a sample feeding transfer part, an active rotating part and a sample scanning part are arranged in the closed sample feeding chamber; the sampling mechanism comprises a sampling needle for aspirating a sample from a sample container in a sampling position; the sample accommodating part is provided with a hole for accommodating a sample container of a blood sample, and an elastic bearing assembly for providing a supporting height and a buffering stroke for the sample container of the peripheral blood sample is arranged in the hole; the sample introduction transfer part is used for moving the sample container to enable the hole position of the sample container to reach the scanning position corresponding to the sample scanning part or reach the sampling position corresponding to the sampling mechanism; the active rotating part is used for driving the sample container arranged in the hole site on the sample containing part to rotate; the sample scanning component is used for scanning the label of the sample container at the scanning position and acquiring sample information of the blood sample.
As an improvement of the sample analyzer, the elastic bearing component comprises a sliding bearing seat and a supporting spring; the sliding bearing seat axially slides along the inner wall of the hole and is provided with an upper end surface and a lower end surface, and the upper end surface is used for bearing a sample container for containing the peripheral blood sample; one end of the supporting spring is connected to the lower end face of the sliding bearing seat, and the other end of the supporting spring is connected to the bottom of the hole position; the sliding bearing seat is used for elastically pushing the loaded sample container of the peripheral blood sample to a height matched with the sample sucking of the sampling needle under the action of the supporting spring; and reserving a buffer stroke for the sample container of the peripheral blood sample when the sampling needle is inserted into and abutting the sample container bottom of the peripheral blood sample.
As another improvement of the sample analyzer, the sample container of the peripheral blood sample is adapted to fit into a cup adapter and be received in the well site; the inside of the cup body adapter is provided with a cavity into which the sample container is inserted in a matching mode, and the outside of the cup body adapter is provided with a column structure which is inserted in the hole in a matching mode.
According to a second aspect, an embodiment provides a sample analyzer, which includes a closed sample feeding chamber, a sample accommodating part, an active rotating part and a sample scanning part are arranged in the closed sample feeding chamber; the sample accommodating part is provided with a first hole site of a first sample container for accommodating a first sample and a second hole site of a second sample container for accommodating a second sample; the active rotating part is used for driving a first sample container to rotate when a first sample container containing a first sample is placed in the first hole, and driving a second sample container to rotate when a second sample container containing a second sample is placed in the second hole; the sample scanning component is used for performing label scanning on the first sample container and the second sample container and acquiring sample information of the first sample and the second sample.
As a further improvement of the sample analyzer, a detection component is further arranged in the closed sample feeding bin and used for determining the sample type fed by the closed sample feeding bin when a sample container is placed in the closed sample feeding bin, and the sample type is divided into a first sample and a second sample.
As a further improvement of the sample analyzer, the closed sample feeding bin further comprises a sample feeding transfer part connected with the sample accommodating part; the sample introduction transfer part is used for transferring the position of the sample containing part; the sample analyzer further comprises a controller, the controller is used for transferring the sample accommodating part through the sample transferring part after the detection part detects and determines the type of the sample injected from the closed sample injection bin, so that a first hole position corresponding to the type of the sample and provided with the first sample container is positioned at a scanning position, or a second hole position corresponding to the type of the sample and provided with the second sample container is positioned at the scanning position; the sample scanning component performing label scanning on the first sample container and the second sample container comprises: performing a label scan on the first sample container in a scan position, or the second sample container in a scan position.
According to a third aspect, an embodiment provides a sample analyzer, which includes a closed sample feeding chamber, a sample accommodating part, a sample feeding transfer part and a sample scanning part are arranged in the closed sample feeding chamber; the sample accommodating member is provided with a first hole site of a first sample container for accommodating a first sample, and a second hole site of a second sample container for accommodating a second sample; the sample introduction transfer part is used for driving the first sample container to move from a placing position for receiving the first sample to a scanning position for scanning the first sample when the first sample container for containing the first sample is placed at the first hole site, and driving the second sample container to move from a placing position for receiving the second sample to a scanning position for scanning the second sample when the second sample container for containing the second sample is placed at the second hole site; the sample scanning component is configured to scan the first sample container when the first sample container is transported to a scanning position and to scan the second sample container when the second sample container is transported to a scanning position.
As an improvement of the sample analyzer, the closed sample feeding bin further comprises an active rotating component; the active rotating component is arranged on one side of the scanning position and drives the first sample container or the second sample container in the scanning position to rotate; the sample scanning component is arranged on the other side of the scanning position, and the sample scanning component scans the first sample container or the second sample container in the scanning position for labels.
As another improvement of the sample analyzer, the closed sample feeding bin further comprises an active rotating component; the active rotating part is arranged on the sample accommodating part and is used for bearing a first sample container placed in the first hole site and a second sample container placed in the second hole site and driving the borne first sample container and/or second sample container to rotate; the sample scanning component is disposed on one side of the scanning position, and the sample scanning component scans the first sample container or the second sample container in the scanning position for a label.
According to a fourth aspect, an embodiment provides a sample analysis method of a sample analyzer, the sample analyzer comprising a closed sample introduction chamber, a first hole site of a first sample container for containing a first sample and a second hole site of a second sample container for containing a second sample are arranged in the closed sample introduction chamber; characterized in that the method comprises: obtaining the sample type of sample injection in the closed sample injection bin by detecting whether a sample container is placed in the first hole site or the second hole site; the sample types are divided into a first sample and a second sample; transferring the first hole site where the first sample container is placed or the second hole site where the second sample container is placed to a scanning site; performing label scanning on the first sample container or the second sample container at the scanning position to obtain corresponding sample information; a sampling needle samples from the first sample container or the second sample container; and detecting the collected sample to obtain a detection result.
As a further improvement of the sample analysis method, after the label scanning is performed on the first sample container or the second sample container at the scanning position, before the sampling needle samples from the first sample container or the second sample container, the method further includes: judging whether the type of the detected sample is consistent with the sample information obtained by scanning, if so, transferring a first hole site provided with the first sample container or a second hole site provided with the second sample container to a sampling position so as to sample; otherwise, alarm information is output.
The beneficial effect of this application is:
according to the sample analyzer and the sample analyzing method thereof of the embodiment, the sample analyzer comprises a closed sample feeding bin which is provided with a sample accommodating part, a sample feeding transfer part, an active rotating part and a sample scanning part; the sample accommodating part is provided with a first hole position of a first sample container for accommodating a first sample and a second hole position of a second sample container for accommodating a second sample; the sample injection transfer component is used for moving the sample container to enable the hole position to reach the scanning position and the sampling position; the active rotating part is used for driving the sample container arranged in the first hole site or the second hole site on the sample containing part to rotate; the sample scanning component is used for performing label scanning on the sample container and acquiring sample information of a peripheral blood sample or a whole blood sample. On the first hand, because the first hole site for placing the first sample container and the second hole site for placing the second sample container are arranged on the sample accommodating part, the automatic sample introduction of the first sample and the second sample is realized, the sample containers and the corresponding hole sites can be accurately adapted, and the risk of the error in the sample introduction of the first sample and the second sample is reduced; in the second aspect, the active rotating part can drive the sample container in the hole site to rotate, so that the label can automatically face the sample scanning part in the rotating process of the sample container, and the efficiency of the sample scanning part in scanning the label is improved; in the third aspect, the sample scanning component is arranged to realize automatic scanning of the label of the sample container, so that the situations that the operation difficulty is increased, the efficiency is low and the sample is misplaced after manual scanning due to manual participation in scanning are avoided. Therefore, the sample analyzer and the control method thereof effectively reduce the risk of sample injection errors.
Drawings
FIG. 1 is a block diagram of one embodiment of a sample analyzer of the present application;
FIG. 2 is a perspective view of a closed sample injection chamber under a sample injection condition in an embodiment;
FIG. 3 is a perspective view of a closed sample introduction chamber under a sample scanning condition in an embodiment;
FIG. 4 is a top view of the closed sample introduction chamber under sample scanning in one embodiment;
FIG. 5 is an enlarged view at C of FIG. 4;
FIG. 6 is an exploded view of a sample-receiving part, a detection part, and a self-resetting hold-down part according to one embodiment;
FIG. 7 is a cross-sectional view taken along line A-A of FIG. 6;
FIG. 8 is a view showing the structure of the detecting unit in a state where the first hole site is restricted;
FIG. 9 is an enlarged view at D of FIG. 8;
FIG. 10 is a view showing the structure of the detecting unit in the case where the second hole is restricted.
FIG. 11 is an enlarged view at E in FIG. 10;
FIG. 12 is a perspective view of a closed sample introduction chamber in a case of sample introduction in the second embodiment;
FIG. 13 is a perspective view of a closed sample introduction chamber under the condition of sample scanning in the second embodiment;
FIG. 14 is a cross-sectional view taken at B-B of FIG. 12;
FIG. 15 is a block diagram of a cup adapter according to one embodiment of the present application;
FIG. 16 is one of modified structural views of the cup adapter;
FIG. 17 is a second modified view of the cup adapter;
FIG. 18 is a third modified structural view of the cup adapter;
FIG. 19 is a schematic view of a closed sample injection system according to an embodiment of the present application;
FIG. 20 is a schematic diagram of a closed sample injection system according to an embodiment;
FIG. 21 is a flow chart of a method of sample analysis in an embodiment of the present application;
FIG. 22 is a flow chart of a method of sample analysis in another embodiment of the present application;
FIG. 23 is a flow chart of sample information obtained by label scanning;
fig. 24 is a flowchart for determining whether sample information is valid.
Detailed Description
The present invention will be described in further detail with reference to the following detailed description and accompanying drawings. Wherein like elements in different embodiments are numbered with like associated elements. In the following description, numerous details are set forth in order to provide a better understanding of the present application. However, those skilled in the art will readily recognize that some of the features may be omitted or replaced with other elements, materials, methods in different instances. In some instances, certain operations related to the present application have not been shown or described in detail in order to avoid obscuring the core of the present application from excessive description, and it is not necessary for those skilled in the art to describe these operations in detail, so that they may be fully understood from the description in the specification and the general knowledge in the art.
Furthermore, the features, operations, or characteristics described in the specification may be combined in any suitable manner to form various embodiments. Also, the various steps or actions in the method descriptions may be transposed or transposed in order, as will be apparent to one of ordinary skill in the art. Thus, the various sequences in the specification and drawings are for the purpose of describing certain embodiments only and are not intended to imply a required sequence unless otherwise indicated where such sequence must be followed.
The numbering of the components as such, e.g., "first", "second", etc., is used herein only to distinguish the objects as described, and does not have any sequential or technical meaning. The term "connected" and "coupled" when used in this application, unless otherwise indicated, includes both direct and indirect connections (couplings).
The application provides a sample analyzer, it includes quick-witted case and inside sample test subassembly, is provided with to seal at the side of quick-witted case and advances a kind storehouse, should seal and advance a kind storehouse and be used for manual putting into or take out the sample container (like the sample cup) that holds blood sample, carries out processing such as position transfer, label scanning and sample suction to the sample container of putting into automatically afterwards.
For example, in the sample analyzer of an embodiment in fig. 1, a closed sample bin 2 is disposed in a front end sample injection region of a chassis 1, when a sample injection operation of a blood sample needs to be performed by using the closed sample injection bin 2, a bin gate is opened and a user manually places a sample container Q containing the blood sample into the closed sample injection bin 2, then the bin gate is closed and closed sample injection is performed, and after the sample injection is completed, the bin gate is opened again to take out the sample container Q. In order to facilitate the scanning and identification of the sample container Q, a label Q0 in the form of a barcode, a two-dimensional code, or the like may be attached to the side surface of the sample container Q.
A sample accommodating part, a sample introduction transfer part, an active rotating part and a sample scanning part are arranged in the closed sample introduction bin. Wherein the sample containing part is used for placing a sample container containing a blood sample; a scanning position and a sampling position are arranged on a transfer track of the sample introduction transfer part and are used for moving a sample container placed on the sample containing part to respectively reach the scanning position and the sampling position; the active rotating component is used for driving the sample container placed on the sample containing component to rotate so as to facilitate the sample scanning component to carry out label scanning on the sample container in the scanning position. When the sample container is transferred to the sampling position, the sampling needle of the sampling mechanism can be inserted into the sample container for sample suction.
The technical solution of the present application is further described in detail by the following detailed description and the accompanying drawings.
The first embodiment,
Referring to fig. 2 to 4, one embodiment provides a sample analyzer, which includes a closed sample feeding chamber and a sampling mechanism. The closed sample introduction bin is mainly internally provided with a sample accommodating part 200, a sample introduction transfer part 100, an active rotating part 400 and a sample scanning part 600; the sampling mechanism 900 includes a sampling needle 901, the sampling needle 901 for drawing a sample from a sample container in a sampling position.
The sample-receiving member 200 is provided with a hole for receiving a sample container of a peripheral blood sample, and an elastic receiving member for providing a supporting height and a buffering stroke for the sample container of the peripheral blood sample is provided in the hole. There are two well locations in FIG. 3, such as first well location 210 and second well location 220, and the well location of the sample container containing the distal blood sample may be either of first well location 210 and second well location 220, since only one well location is protected in this embodiment. If the well site of the sample container containing the peripheral blood sample in this embodiment is referred to as the first well site 210, a first sample container Q1 may be placed therein; if the well site of the sample container containing the peripheral blood sample in this embodiment is referred to as the second well site 220, a second sample container Q2 may be placed in the well site. In addition, referring to fig. 3, for the first hole site 210 and the second hole site 220, the sides thereof opposite to the sample scanning component 600 are both provided with openings, so as to form a chamber with unsealed sides, thereby facilitating the side of the sample container in the hole site to be displayed at the scanning window of the sample scanning component 600.
It should be noted that, in the present embodiment, the sample container for receiving the peripheral blood sample, whether it is the first sample container Q1 or the second sample container Q2, may be a common sample cup. Of course, different sample cups can be selected for collecting different blood samples (such as peripheral blood and whole blood of a human body) according to actual conditions. For example, since a peripheral blood sample usually has a small amount of blood, a sample cup dedicated to a small amount of blood can be used as the sample container.
In this embodiment, for the well site of the sample container for receiving the peripheral blood sample, the elastic receiving member provided in the well site includes a slide receiver and a support spring. The sliding bearing seat axially slides along the inner wall of the hole and is provided with an upper end surface and a lower end surface, and the upper end surface is used for bearing a sample container for containing a peripheral blood sample; one end of the supporting spring is connected to the lower end face of the sliding bearing seat, and the other end of the supporting spring is connected to the bottom of the hole site. The sliding bearing seat is used for elastically pushing the sample container of the carried peripheral blood sample to a height matched with the sample sucking of the sampling needle under the action of the supporting spring, so that the sampling needle can be smoothly inserted into the sample container and the sample sucking operation can be carried out; in addition, the sliding bearing seat is also used for reserving a certain buffer stroke for the sample container of the peripheral blood sample when the sampling needle is inserted into and collides with the bottom of the sample container of the peripheral blood sample, so that the sampling needle can be inserted into the bottom of the sample container and suck the sample as much as possible, and the sampling needle can be protected from being damaged when colliding with the bottom of the sample container.
Further, the elastic bearing assembly also comprises a base and a sliding rod. The base is fixed at the bottom of the hole site, a slide rod channel is arranged on the upper surface of the base, and the slide rod channel and the supporting spring are located on the same axis. The sliding rod penetrates through the supporting spring along the axis, one end of the sliding rod is connected to the lower end face of the sliding bearing seat, and the other end of the sliding rod extends into the sliding rod channel.
For example, in FIG. 7, if the first hole 210 is used as a hole for receiving a sample container of a peripheral blood sample, a resilient receiving member is disposed in the first hole 210 to provide a supporting height and a buffering stroke for the inserted first sample container. The elastic receiving member includes a supporting spring 213 and a sliding receiving seat 211; the sliding bearing seat 211 axially slides along the inner wall of the first hole site 210 and is formed with an upper end surface and a lower end surface, and the upper end surface of the sliding bearing seat 211 is used for bearing a first sample container for accommodating a first sample; one end of the support spring 213 is connected to the lower end surface of the slide bearing 211, and the other end is connected to the bottom of the first hole 210. With reference to fig. 7, in order to ensure that the sliding socket 211 has a stable sliding effect, a base 214 and a sliding rod 212 may be disposed on the sliding socket 211, the base 214 is fixed at the bottom of the first hole 210, and a sliding rod channel is disposed on the surface of the base, the sliding rod 212 is disposed in the cavity of the supporting spring 213, and one end of the sliding rod 212 extends into the sliding rod channel, and the other end is connected to the lower end surface of the sliding socket 211.
The sample injection transfer part 100 is provided with a scanning position and a sampling position on the transfer track, and the sample injection scanning part 100 is used to move the sample container to make the hole position reach the scanning position corresponding to the sample scanning part 600 or reach the sampling position corresponding to the sampling mechanism 900. For example, as shown in fig. 2, the sample introduction transfer part 100 drives the sample accommodating part 200 to move, so that the second hole position 220 reaches the scanning position, and the sample scanning part 600 scans the label 221 of the second sample container Q2 in the second hole position 220; in addition, the sample introduction transfer part 100 can also drive the sample accommodating part 200 to move and enable the second hole site 220 to reach the sampling position, so that the sampling needle 901 of the sampling mechanism 900 is inserted into the second sample container Q2 of the second hole site 220 for sample suction.
The active rotation component 400 is provided with a rotation component for driving the sample container disposed in the hole on the sample holding component 200 to rotate. The rotating member of the active rotating member 400 may rotate the sample container by abutting against the side of the sample container, such as in the case of fig. 2-4.
Of course, the active rotation member 400 may also rotate the sample container by bearing against the bottom surface of the sample container, such as in the case of fig. 12-13.
The sample scanning component 600 has a label scanning window for scanning a label of a sample container in a scanning position and obtaining sample information of a peripheral blood sample. Referring to the sample scanning unit 600 in fig. 3, it is disposed at the side of the scanning position so that its scanning window is facing the sample container at the scanning position, so that the sample container is scanned for the label while the sample container is rotated and the label is displayed.
Fig. 2 to 4 of this embodiment provide a structure for closing a sample inlet chamber, and the sample inlet transfer unit 100 is connected to the sample accommodating unit 200 for transferring the position of the sample accommodating unit 200. Moreover, the active rotating component 400 is arranged at one side of the scanning position and drives the sample container at the scanning position to rotate; the sample scanning unit 600 is disposed on the other side of the scanning position, and the sample scanning unit 600 scans the label of the sample container in the scanning position. For example, referring to fig. 3, the sample introduction transfer unit 100 drives the second hole site 220 of the second sample container Q2 containing the second sample (for example, a distal blood sample) on the sample containing unit 200 to the scanning position, the active rotation unit 400 laterally abuts against the second sample container Q2 and rotates the second sample container Q2, and the sample scanning unit 600 scans the label of the rotating second sample container Q2 in the scanning position, so that the label 221 on the second sample container Q2 can be easily scanned.
In one embodiment, referring to fig. 4, the active rotation part 400 includes a rotation wheel 413 and a first motor 411 for powering the rotation wheel 413, and the first motor 411 drives the rotation wheel 413 to rotate through a belt 412. The rotation wheel 413 is disposed at one side of the scanning position, and an outer diameter edge of the rotation wheel 413 is used for contacting with a side surface of the sample container at the scanning position, so that the rotation wheel 413 rotates the sample container by its rotation.
Further, in order to ensure that the rotation wheel 413 of the rotation member 400 is reliably contacted with the side of the sample container and stably drives the sample container to rotate, an elastic plunger member 700 and a self-resetting pressing member 800 may be additionally provided in the closed sample introduction chamber. Referring to fig. 2 to 4, a self-resetting pressing part 800 is movably provided on the sample-accommodating part 200, and an elastic plunger part 700 is provided at the other side of the scanning position; the elastic plunger member 700 is used to elastically push the self-resetting pressing member 800 to press the sample container in the hole site when the sample container in the hole site (for example, the second sample container Q2 in the second hole site 220) reaches the scanning position, so that the sample container can smoothly rotate under the driving of the driving rotating member 400.
In fig. 12 to 13 of this embodiment, another structure for closing the sample inlet chamber is provided, and the sample inlet transfer member 100 is connected to the sample accommodating member 200 and the active rotation member 400, and is used for simultaneously transferring the positions of the sample accommodating member 200 and the active rotation member 400. The active rotation component 400 is disposed at the bottom of the sample container 200, and is used for bearing the first sample container Q1 in the first hole 210 and the second sample container Q2 in the second hole 220 on the sample container 200 from the bottom and driving the borne sample containers to rotate; since the sample receiving part 200 and the active rotation part 400 are integrally designed, the sample transfer part 100 needs to move together with them. Further, a sample scanning unit 600 is provided at one side of the scanning position for performing label scanning on the sample container at the scanning position. For example, referring to fig. 13, the sample introduction transfer unit 100 drives the second hole site 220 of the second sample container Q2 containing the second sample (for example, a distal blood sample) on the sample containing unit 200 to the scanning position, the active rotation unit 400 abuts against the second sample container Q2 from the bottom surface and rotates the second sample container Q2, and the sample scanning unit 600 scans the label of the rotating second sample container Q2 in the scanning position, so that the label on the second sample container Q2 can be easily scanned.
Referring to fig. 12, the active rotation member 400 includes a first guide bar and a second motor. The first guide rod is arranged at the bottom of the hole site, and a bearing part for bearing the sample container is formed at the top end of the first guide rod; the second motor is in transmission connection with the first guide rod and is used for driving the first guide rod to rotate so as to drive the sample container carried by the first guide rod to rotate. For example, as shown in fig. 14, in order to allow the second sample container Q2 in the second hole site 220 to rotate, in the active rotation component 400, the guide bar 427 may be used as a first guide bar, and a bearing part for bearing the first sample container Q1 is formed at the top of the guide bar 427; the motor 421 serves as a second motor, and the driving pulley 422 of the motor 421 rotates the guide rod 427 by driving the driven pulley 423, so as to drive the second sample container Q2 to rotate.
After the sample scanning component 600 scans the label of the sample container (such as the first sample container Q1 or the second sample container Q2) in the scanning position, the sample introduction transfer component 100 needs to drive the sample containing component 200 to move continuously so that the sample container reaches the sampling position, and the sampling needle 901 of the sampling mechanism 900 can be inserted into the sample container for sample suction.
Because the position of the sampling mechanism 900 is often higher than the closed sample feeding bin, the operation requirement that the sampling needle 901 is inserted into the sample container from top to bottom is met, the structural design causes that liquid (such as sample solution, cleaning solution and the like) attached to the sampling needle 901 may drop into the closed sample bin, in order to avoid polluting the closed sample bin, the closed sample bin further comprises a drip-proof isolation component 500, and the drip-proof isolation component 500 is used for preventing the liquid attached to the sampling needle from dropping into the closed sample bin.
In one embodiment, referring to fig. 2 and 12, the drip-proof isolation component 500 is a baffle plate disposed on the top of the closed sample bin, and at least one hollow 501 is formed on the baffle plate, and the hollow 501 is used for allowing the sampling needle 901 to pass through and reach the sampling position in the closed sample bin. Because the sampling needle 901 can only be stretched into to seal and advance the kind storehouse through cavity 501 in, the risk greatly reduced in the sealed sample storehouse of liquid drippage on the sample needle 901 then, even if the sampling needle 901 can carry out the ascending removal in a plurality of directions along with the sampling mechanism 900, the upper surface at the baffle also can be fallen to the liquid that drips to the inside of having avoided liquid pollution to seal and advance the kind storehouse. Referring to fig. 3, in order to facilitate cleaning of the anti-dripping isolation component 500, it is preferable to provide a baffle of the anti-dripping isolation component 500 to be detachably or rotatably connected with the closed sample feeding bin.
In one embodiment, to accommodate sample containers of different sizes that can be securely placed into the well site of a sample container containing a peripheral blood sample, a cup adapter can be provided for the sample container such that the sample container is adapted to fit into the cup adapter and be received within the well site. Such as the cup adapter 230 of fig. 15, the interior of the cup adapter 230 may be formed with a cavity into which the sample container is fittingly inserted, and the exterior of the cup adapter 230 may be formed with a post structure that fits into the insertion hole.
In one embodiment, to meet the requirement of closed sample injection in the closed sample injection chamber, the closed sample injection chamber further comprises a chamber door 105 as illustrated in fig. 2 and 12, and the chamber door 105 can be set as a chamber door which is opened manually or automatically. The sample transfer unit 100 is provided with a delivery position on the transfer track, and the delivery position is close to the gate 105. The sample accommodating part 200 can make the first hole site 210 and the second hole site 220 on it reach the exit position under the driving of the sample transfer part 100, so when the door 105 is opened, the user can conveniently put in or take out the first sample container Q1 in the first hole site 210, or put in or take out the second sample container Q2 in the second hole site 220.
Example II,
Referring to fig. 2 to 4, the present embodiment provides a sample analyzer, which is mainly different from the sample analyzer of the first embodiment in that two holes are disposed on the sample accommodating member, and the two holes are adapted to accommodate sample containers of different blood samples.
In this embodiment, the sample analyzer includes a closed sample chamber, in which the sample accommodating part 200, the active rotation part 400, and the sample scanning part 600 are mainly disposed. The sample-accommodating member 200 is provided with a first hole site 210 of a first sample container Q1 for accommodating a first sample, and a second hole site 220 of a second sample container Q2 for accommodating a second sample. The active rotation member 400 is used to rotate the first sample container Q1 when the first sample container Q1 containing the first sample is placed at the first well site 210, and to rotate the second sample container Q2 when the second sample container Q2 containing the second sample is placed at the second well site 220. The sample scanning section 600 is configured to perform label scanning on the first sample container Q1 and the second sample container Q2, and acquire sample information of the first sample and the second sample.
In this embodiment, in order to enable the first sample container Q1 placed in the first hole site 210 and the second sample container Q2 placed in the second hole site 220 to smoothly perform label scanning and sample needle aspiration, a scanning position and a sampling position are provided in the closed sample introduction cabin, the first sample container Q1 or the second sample container Q2 performs label scanning when in the scanning position, and the first sample container Q1 or the second sample container Q2 performs sampling when in the sampling position. Then, the sample scanning component 600 may be disposed on one side of the scanning position for label scanning of the sample container in the scanning position, and the sampling mechanism 900 may be disposed above the sampling position for insertion and aspiration of the sampling needle of the sample container in the sampling position.
In one embodiment, the sample-receiving component 200 can be configured as either a non-movable component or a movable component. If the sample holding part 200 is not movable, the scanning position and the sampling position can be set to be the same position in the closed sample feeding bin; if the sample accommodating part 200 is movable, the scanning position and the sampling position can be set to different positions in the closed sample feeding bin respectively, and at the moment, only one sample feeding transfer part needs to be arranged to move the sample accommodating part to different positions.
Further, in order to detect which hole site of the first hole site 210 and the second hole site 220 can be placed with a sample container, and further determine the sample type injected by the closed sample injection bin, a detection component is further disposed in the closed sample injection bin, and the detection component is used for determining the sample type injected by the closed sample injection bin when the sample container is placed in the closed sample injection bin, wherein the sample type is divided into two types, i.e., a first sample and a second sample, such as a peripheral blood sample (a trace blood sample) of a human body and a whole blood sample.
In one embodiment, the detection component comprises a limiting component and a sensing component. The limiting assembly is movably connected to the sample accommodating part and used for limiting the first sample container to be placed in the first hole site or limiting the second sample container to be placed in the second hole site. The induction assembly is arranged in the movable area of the limiting assembly and used for inducing the limiting state of the limiting assembly for the first hole site or the second hole site and determining the type of a sample injected from the closed sample injection bin according to the limiting state. It will be appreciated that the spacing element may be some sort of manual or motorized stop or stop, and the sensing element may be a touch switch or sensor that generates some sort of signal.
Referring to fig. 6, 8 to 11, the limit component and the sensing component of the detection component 300 are a limit plate 301 and a microswitch 304, respectively. Wherein, the limiting plate 301 is rotatably connected to the outside of the sample holding member 200 and close to the first hole site 210 and the second hole site 220, for example, disposed in the middle of the two hole sites; the limiting plate 301 is provided with a manual shifting head, and the manual shifting head is used for driving the limiting plate 301 to cover the first hole site 210 or the second hole site 220 under the shifting of a user, so that only one hole site is allowed to be placed into the sample container at the same time. The limiting plate 301 is further provided with a contact 302 abutting against the microswitch 304, and the contact 302 is used for triggering the microswitch 304 when the limiting plate covers the first hole site 210 or the second hole site 220; the micro switch 304 is used to detect which of the first aperture site 210 and the second aperture site 220 is activated for placement of a sample container. For example, referring to fig. 8 and 9, when the limiting plate 301 covers the first hole site 210, the contact 302 is located at one end of the elastic piece 303 on the micro switch 304, and since the elastic piece 303 is not pressed down at this time, the micro switch 304 does not generate a trigger signal, it is characterized that a sample container is not allowed to be placed in the first hole site 210, and since a second sample container can only be placed in the second hole site 220, the sample injection type of the closed sample injection chamber is a second sample. For example, in fig. 10 and 11, when the limiting plate 301 covers the second hole site 220, the contact 302 is located at the other end of the elastic piece 303 on the micro switch 304, and at this time, the elastic piece 303 is pressed down by the contact 302, and then the micro switch 304 generates a trigger signal, which indicates that the sample container is not allowed to be placed in the second hole site 220, and since the first sample container can only be placed in the first hole site 210, the sample introduction type of the closed sample introduction chamber is the first sample.
It should be noted that the purpose of providing the limiting plate 301 on the detecting component 300 is to ensure that only one hole site is activated in the first hole site 210 and the second hole site 220 at the same time, so that the type of the sample injected in the closed sample injection bin is uniquely determined during each sample injection, thereby avoiding the occurrence of a sample injection error easily caused by simultaneous sample injection in two hole sites.
Of course, in some embodiments, the limiting plate 301 may be removed from the detecting member and the micro switch 304 may be retained, and the elastic sheet 303 may be pressed to manually trigger the micro switch 304 when the sample injection operation needs to be performed on the second sample container Q2 placed in the second hole site 220.
Further, in an embodiment, the sample analyzer further includes a controller (not shown in fig. 2 to 4), and the sample information scanned by the sample scanning component 600 includes a sample type, the controller is configured to determine whether the sample type detected by the detecting component 300 is consistent with the sample type scanned by the sample scanning component 600, and if not, output an alarm message.
It should be noted that, since the first hole site 210 is used for placing the first sample container Q1 accommodating the first sample, and the second hole site 220 is used for placing the second sample container Q2 accommodating the second sample, the controller can detect whether the first hole site 210 or the second hole site 220 is placed in the sample container through the detecting component 300 to know whether the first sample or the second sample is required to be injected; because the labels are adhered to the first sample container Q1 and the second sample container Q2, the controller can know whether the sample is the first sample or the second sample through the sample information obtained by scanning the sample scanning component 600, so that the controller can judge whether the sample types are consistent, and the output alarm information comprises information in the forms of sample type error, sample container placement error, label non-scanning and the like.
Further, in order to facilitate transferring the sample accommodating part 200 so that the first hole site 210 and the second hole site 220 reach the preset scanning position and the sampling position, the closed sample injection cabin further includes a sample injection transferring part 100 connected to the sample accommodating part 200, the sample injection transferring part 100 is used for transferring the position of the sample accommodating part 200, and the transfer track is provided with the scanning position and the sampling position.
In one embodiment, the sample analyzer further comprises a controller (not shown in fig. 2 to 4) configured to transfer the sample accommodating member 200 through the sample transfer member 100 after the detecting member 300 determines the type of the sample injected from the closed sample chamber, so that the first hole site 210 corresponding to the type of the sample (such as the first sample) and having the first sample container Q1 placed therein is in the scanning position, or the second hole site 220 corresponding to the type of the sample (such as the second sample) and having the second sample container Q2 placed therein is in the scanning position; then the sample scanning component 600 may perform a label scan on either the first sample container Q1 in the scan position or the second sample container Q2 in the scan position.
Referring to fig. 3, since the sample accommodating part 200 is provided with the first hole site 210 of the first sample container Q1 for accommodating the first sample and the second hole site 220 of the second sample container Q2 for accommodating the second sample, the introduction transfer part 100 can move the first sample container Q1 from the placing position for receiving the first sample to the scanning position for scanning the first sample when the first sample container Q1 for accommodating the first sample is placed at the first hole site 210 and move the second sample container Q2 from the placing position for receiving the second sample to the scanning position for scanning the second sample when the second sample container Q2 for accommodating the second sample is placed at the second hole site 220. Thereafter, the sample scanning component 600 is able to scan the first sample container Q1 when the first sample container Q1 is transported to the scanning position, and to scan the second sample container Q2 when the second sample container Q2 is transported to the scanning position.
In one embodiment, referring to fig. 3 and 4, the sample transfer unit 100 includes a guide rail 103, a belt 102, and a motor 101. The guide rail 103 is fixedly arranged at the bottom of the closed sample feeding bin, and the sample accommodating part 200 is connected to the guide rail 103 in a sliding manner; the motor 101 is in transmission connection with the sample accommodating part 200 through a belt 102, and is used for driving the sample accommodating part 200 to move along the guide rail 103 and reach a scanning position and a sampling position on the transfer track. In order to facilitate a user to put or take a sample container into or out of the sample accommodating part 200, a track metal plate 104 is arranged on one side of the guide rail 103, an inclined rail pointing to the bin outlet is formed on the track metal plate 104, and a block with one end fixed on the sample accommodating part is arranged in the inclined rail; then, the trace sheet metal 104 is used to generate an inclined state that the first hole site 210 and the second hole site 220 on the sample accommodating part 200 face the outlet when the sample accommodating part 200 moves to the outlet, so that a user can conveniently put in or take out a sample container in the first hole site 210 and the second hole site 220.
Fig. 2 to 4 of this embodiment provide a structure for sealing the sample feeding chamber, which is described in detail below.
The closed sample compartment in fig. 2 further comprises a sample transfer part 100 connected to the sample receiving part 200. Since the scanning position is provided on the transfer track of the sample holding member 200, the active rotation member 400 is disposed on one side of the scanning position, and the sample scanning member 600 is disposed on the other side of the scanning position, so that the active rotation member 400 rotates the first sample container Q1 or the second sample container Q2 in the scanning position, and the sample scanning member 600 scans the first sample container Q1 or the second sample container Q2 in the scanning position.
Referring to fig. 4, the driving rotation part 400 includes a rotation wheel 413 and a first motor 411 for powering the rotation wheel 413, and the rotation wheel 413 is rotated by the first motor 411 through a belt 412. The outer diameter edge of the rotation wheel 413 is used to contact the side of the sample container in the scanning position, so that the rotation wheel 413 rotates the sample container by its rotation. For example, as shown in fig. 5, the outer diameter edge of the rotating wheel 413 abuts against the side of the second sample container Q2 and rotates to drive the second sample container Q2 to rotate.
To ensure that the rotation wheel 413 of the rotation member 400 reliably contacts with the side of the sample container and stably drives the sample container to rotate, the closed sample chamber further comprises an elastic plunger member 700 and two self-resetting pressing members 810 and 820 (or collectively indicated by reference numeral 800 in fig. 2 and 8) respectively corresponding to the first hole site 210 and the second hole site 220. Referring to fig. 4, the self-resetting pressing parts 810 and 820 are movably disposed on the sample-accommodating part 200, and the elastic plunger part 700 is disposed at the other side of the scanning position; the elastic plunger member 700 is used for elastically pushing the self-resetting pressing member 810 to press the first sample container Q1 in the first hole site 210 when the first sample container Q1 in the first hole site 210 reaches the scanning position, so that the first sample container Q1 can smoothly rotate under the driving of the driving rotating member 400. Similarly, the elastic plunger member 700 is further configured to elastically push the self-resetting pressing member 812 to press the second sample container Q2 in the second hole site 220 when the second sample container Q2 in the second hole site 220 reaches the scanning position, so that the second sample container Q2 can smoothly rotate under the driving of the active rotating member 400.
For example, in fig. 4 and 6, the self-resetting pressing component 810 comprises a support (not shown in fig. 4), a pressing part 812 and a return spring 813, wherein the support is fixed on the sample accommodating component 200 and close to the corresponding first hole 210, the pressing part 812 is slidably disposed on the support and is used for abutting against the side surface of the first sample container Q1 in the corresponding hole, and two ends of the return spring 813 are respectively fixed on the pressing part 812 and the support and are used for resetting the pressing part 812. In order to improve the contact state of the pressing part 812 with the side surface of the first sample container Q1 and achieve better rotation effect, two pulleys 811 located on the same plane may be provided at the head of the pressing part 812, and the two pulleys 811 are used for being engaged and abutted against the side surface of the first sample container Q1 to press the first sample container Q1 and can rotate with the first sample container Q1.
Self-resetting pressing component 820 has the same structure as self-resetting pressing component 810, and also comprises a support (not shown in fig. 4), a pressing part 822 and a return spring 823, wherein the support is fixed on sample accommodating component 200 and close to the corresponding second hole site 220, pressing part 822 is slidably arranged on the support and is used for abutting against the side surface of second sample container Q2 in the corresponding hole site, and two ends of return spring 823 are respectively fixed on pressing part 822 and support and are used for resetting pressing part 822. In addition, the head of the pressing part 822 is provided with two pulleys 821 in the same plane, and the two pulleys 821 are used for abutting against the side surface of the second sample container Q2 to press and rotate with the second sample container Q2.
For example, fig. 3, 4 and 6, the elastic plunger member 700 includes a pressure head seat 702 and an elastic pressure head 701, the pressure head seat 702 is fixed at the other side of the scanning position, and the elastic pressure head 701 is assembled on the pressure head seat 702 through a compression spring. The tail of the pressing part 812 of the self-resetting pressing part 810 is provided with a sliding surface 814, and the sliding surface 814 is inclined relative to the transfer track transferred by the sample accommodating part 200; likewise, the tail portion of the pressing portion 822 of the self-resetting pressing member 820 is also provided with a sliding surface 824, and the sliding surface 824 is inclined with respect to the transfer trajectory thereof following the transfer of the sample-accommodating member 200. During the process that the first sample container Q1 in the first hole site 210 moves to the scanning position, the end of the elastic pressure head 701 is located on the transfer track of the sliding surface 814, and the elastic pressure head 701 gradually pushes the pressing part 812 to press the corresponding first sample container Q1 by changing the position of interference with the sliding surface 814. During the process that the second sample container Q2 in the second hole site 220 moves to the scanning position, the end of the elastic ram 701 is located on the transfer track of the sliding surface 824, and the elastic ram 701 gradually pushes the pressing part 822 to press the corresponding second sample container Q2 by changing the position of interference with the sliding surface 824.
Of course, a metal plate 830 may be further provided in fig. 4, the metal plate 830 is fixed at the tail end of the support in the self-resetting pressing component 810 and the support in the self-resetting pressing component 820, and when the self-resetting pressing component 810 and the self-resetting pressing component 820 are not pushed by the elastic ram 701, the sliding surface 814 in the self-resetting pressing component 810 and the sliding surface 824 in the self-resetting pressing component 820 are attached to the metal plate 830 to define the resetting positions of the pressing parts 812 and 822.
It should be noted that the elastic pressure head 701 plays a role of pushing the pressing portions 812, 822 to move to the corresponding hole positions, the return spring 813 plays a role of pulling the pressing portions 812, 822 to reset in reverse direction, and at this time, in order to ensure that the elastic pressure head 701 can push the pressing portions 812 or 822 to move, the elastic force of the compression spring on the elastic pressure head 701 should be greater than that of the return spring 813 or the return spring 823.
In some embodiments, in order to allow a certain buffer stroke for the sample container when the sampling needle is inserted into and abutting against the bottom of the sample container, a spring loaded assembly may be provided in the hole into which the sample container is placed. For example, as shown in fig. 7, an elastic receiving member is disposed in the first hole 210 to provide a buffering stroke for the inserted first sample container, and the elastic receiving member includes a spring 213 and a sliding receiving seat 211; the sliding bearing seat 211 axially slides along the inner wall of the first hole site 210 and is formed with an upper end surface and a lower end surface, and the upper end surface of the sliding bearing seat 211 is used for bearing a first sample container for accommodating a first sample; one end of the spring 213 is connected to the lower end surface of the slide bearing 211, and the other end is connected to the bottom of the first hole 210. Referring to fig. 7, in order to ensure that the sliding socket 211 has a stable sliding effect up and down, a base 214 and a sliding rod 212 may be disposed on the sliding socket 211, the base 214 is fixed at the bottom of the first hole 210, a sliding rod channel is disposed on the surface of the base, the sliding rod 212 is disposed in the cavity of the spring 213, one end of the sliding rod 212 extends into the sliding rod channel, and the other end of the sliding rod 212 is connected to the lower end surface of the sliding socket 211.
Fig. 12 to 13 of this embodiment provide a structure for closing the sample inlet chamber, which will be described in detail below.
The closed sample compartment in fig. 12 further comprises a sample transfer member 100 connected to the sample receiving member 200 and the active rotary member 400, the sample transfer member 100 being configured to simultaneously transfer the positions of the sample receiving member 200 and the active rotary member 400. In addition, the closed sample inlet bin in fig. 12 is different from that in fig. 2 in that an active rotation member 400 is disposed at the bottom of the sample accommodating member 200 and moves together with the sample accommodating member by being moved by the sample inlet transfer member 100.
Since the sample transfer part 100, the detection part 300, the sample scanning part 600, the drip-proof isolation part 500, and the sampling mechanism 900 in fig. 12 and 1 have the same structures as those in fig. 2, they will not be described again here.
Referring to fig. 12, the active rotation member 400 is disposed at the bottom of the sample container 200, and is configured to support the first sample container Q1 in the first hole 210 and the second sample container Q2 in the second hole 220 of the sample container 200 from the bottom and drive the supported sample containers to rotate. Since the sample receiving part 200 and the active rotation part 400 are integrally designed, the sample transfer part 100 needs to move together with them. Further, a sample scanning unit 600 is provided at one side of the scanning position for performing label scanning on the sample container at the scanning position.
Referring to fig. 13, the sample introduction transfer unit 100 drives the second hole site 220 of the second sample container Q2 containing the blood sample on the sample containing unit 200 to reach the scanning position, the active rotation unit 400 abuts against the second sample container Q2 from the bottom surface and rotates the second sample container Q2, and the sample scanning unit 600 scans the label of the rotating second sample container Q2 at the scanning position, so that the label on the second sample container Q2 can be easily scanned.
Further, referring to fig. 12 and 14, the active rotation member 400 includes a first guide bar 427, a second guide bar 428, and a second motor 421. The first guide rod 427 is arranged at the bottom of the first hole site 210, and the top end thereof is provided with a bearing part for bearing the first sample container Q1 in the first hole site 210; the second guide rod 428 is disposed at the bottom of the second hole site 220, and a receiving portion for receiving the second sample container Q2 in the second hole site 220 is formed at the top end thereof; then, the second motor 421 is drivingly connected to the first guide rod 427 and the second guide rod 428, and is used to drive the first guide rod 427 or the second guide rod 428 to rotate so as to drive the first sample container Q1 and the second sample container Q2 carried by the first guide rod 427 or the second guide rod 428 to rotate.
Referring to fig. 14, the second motor 421 drives the first guide rod 427 and the second guide rod 429 to rotate through the gear box 426. A driving pulley 422 is arranged on a rotating shaft of the second motor 421, driven pulleys 423 and 424 are respectively arranged on the first guide rod 427 and the second rotating rod 429, and the driving pulley 423 and the driven pulleys 423 and 424 are in transmission connection through a belt 424.
In some embodiments, in order to allow a certain buffer stroke for the sample container when the sampling needle is inserted into and abutting against the bottom of the sample container, a spring loaded assembly may be provided in the hole into which the sample container is placed. For example, as shown in fig. 14, a resilient receiving member is disposed in the first hole 210 to provide a cushioning stroke for the inserted first sample container Q1, and includes a spring 429 and a sliding receptacle 431; the sliding bearing seat 431 axially slides along the inner wall of the first hole 210 and is formed with an upper end surface and a lower end surface, and the upper end surface of the sliding bearing seat 431 is used for bearing a first sample container Q1 for accommodating a first sample; the spring 429 is sleeved on the second guide rod 428, and one end of the spring 429 is connected to the lower end surface of the sliding receptacle 431, and the other end is connected to the bottom of the first hole 210.
Referring to fig. 14, in order to ensure the sliding socket 431 to have a stable sliding effect up and down, a hollow passage 426 may be formed on the driven pulley 424 of the second guide rod 428, and the bottom end of the second guide rod 428 penetrates into the hollow passage 426 and slides up and down along the hollow passage 426. In order to ensure that the second guide rod 428 can slide up and down in the hollow channel 426, and the driven pulley 424 can still drive the second guide rod 428 to rotate, a limit screw 432 is arranged in the hollow channel 426, and the limit screw 432 also plays a role in limiting the sliding position of the second guide rod 428.
Referring to fig. 14, in order to stably support the first sample container Q1 on the slide bearing 431, an elastic rubber ring 433 is provided on the upper end surface of the slide bearing 431, and the elastic rubber ring 433 is adapted to the bottom surface of the first sample container Q1 to increase the frictional force when contacting with the bottom surface of the first sample container Q1.
In one embodiment, to accommodate sample containers of different sizes that can be securely placed in corresponding wells, a cup adapter can be provided for the sample container such that the sample container is adapted to fit into the cup adapter and be received in the well. A cavity into which the sample container is fittingly inserted may be formed inside the cup adapter, and a cylindrical structure fitted into the insertion hole may be formed outside the cup adapter.
For example, as shown in fig. 15, the cup adapter 230 includes a housing 231, the housing 231 is cylindrical to fit into the insertion hole, and a chamber 232 with one open end is formed inside the housing 231 to fit into the sample container; a handle 233 may also be provided at the top of the housing 231 to lift the housing 231 out of the hole site.
Fig. 16 is a view showing a cup adapter of a first modification of fig. 15, in which a transparent portion 234 is provided on a housing 231 of the cup adapter 230 in fig. 16 to at least correspond to a label affixed to a side surface of a sample container, and the transparent portion 234 is used to look through the sample container placed in the cavity 232 for label scanning of the label affixed to the sample container.
Fig. 17 is a view of fig. 15 showing a second alternative embodiment of the bowl adapter, and fig. 17 shows a plurality of ribs 235 on the side of the shell 231 of the bowl adapter 230, with spaces (e.g., spaces 236) between adjacent ribs for communicating with the interior chamber, each space having a width greater than the width of a label placed on the side of a sample container placed in the cavity 232 for unobstructed viewing of the label applied to the sample container and scanning of the label.
Fig. 18 shows a cup adapter of a third modification of fig. 15, in which one or more bosses 237 are formed at the bottom of the housing 231 of the cup adapter 230 in fig. 18, and the bosses 237 are used for engaging one or more slots formed on the upper end surface of the slide bearing in the hole, so that the cup adapter 230 can be stably placed on the slide bearing in the hole.
It should be noted that the cup adapter provided in fig. 15-18 can be adapted to fit both the first sample container Q1 and the first hole site 210, and the second sample container Q2 and the second hole site 220, and is not limited herein.
Example III,
The embodiment discloses a sample analysis system, which comprises a sample bin controller, an analyzer main control system, a sample management subsystem and a hospital information subsystem.
Referring to fig. 19, the sample bin controller 10 and analyzer master 20 are disposed within a sample analyzer as disclosed in example two. The sample chamber controller 10 is configured to perform timing control on each component (such as the detection component 300, the sample transfer component 100, the active rotation component 400, and the sample scanning component in fig. 2 and 12) in the closed sample chamber; the analyzer main controller 20 is configured to perform timing control on other detection components (such as a sampling mechanism, a liquid path mechanism, a chemical detection mechanism, a microscopic examination mechanism, etc.) in the analyzer. In addition, the sample management subsystem is in communication connection with the analyzer main control 20 and is used for storing and managing detection information detected by the analyzer main control 20; the hospital information subsystem 40 is connected with the sample management subsystem and is used for storing and managing the clinic information of the patient and the detection information of the blood sample of the patient.
In this embodiment, the sample chamber controller 10 controls related components in the closed sample introduction chamber, determines the type of a sample in a sample container, and obtains sample information of the sample; the analyzer main control 20 can control related detection components in the analyzer according to the sample bin controller 10, and perform sampling and detection of samples in the sample container according to sample information to obtain detection information of blood samples. The analyzer master control 20 transmits the test information of the sample to the sample management subsystem 30 for uniform storage management of the information, and the sample management subsystem 30 retransmits the stored test information to the hospital information subsystem 40 for medical personnel to view and issue test reports.
In certain embodiments, the sample management subsystem 30 interfaces with a plurality of sample analyzers to communicate with analyzer masters within each sample analyzer.
In some embodiments, the analyzer main control 20 in the sample analyzer is directly in communication connection with the hospital information subsystem 40, so as to directly transmit the detection information of the blood sample of the patient to the hospital information subsystem 40, and also receive the detection instruction issued by the hospital information subsystem 40, so as to detect the blood sample of the patient according to the detection mode set by the medical staff.
In one embodiment, referring to fig. 20, the sample compartment controller 10 is in signal connection with the detection component 300, the sample introduction transfer component 100, the active rotation component 400, and the sample scanning component 600 of fig. 2 (or fig. 12). The sample bin controller 10 comprises a processor, a driving unit, a sensor signal processing unit, a sample information processing unit, a storage unit and a communication unit; the processor is used for generating a time sequence control signal aiming at each component, and the driving unit is used for driving each component to carry out corresponding work according to the time sequence control signal; the sensor signal processing unit is used for receiving a trigger signal of a microswitch in the detection component; the sample information processing unit is used for analyzing and processing the scanning result of the sample scanning component and obtaining sample information; the storage unit is used for storing the obtained sample information; the communication unit is used for performing communication control with the analyzer main control 20.
In one embodiment, referring to fig. 20, the analyzer main control 20 includes a user interaction unit, a peripheral unit, a CPU, a storage unit, and a communication unit. The analyzer comprises a user interaction unit, a peripheral unit and an analysis unit, wherein the user interaction unit is used for receiving information input by a user through equipment such as keys, knobs and a touch screen, and the peripheral unit is used for managing and controlling external equipment of the analyzer; the CPU is used for generating a time sequence control signal of each detection assembly in the analyzer and analyzing and processing a detection result; the storage unit is used for storing the detection information; the communication unit is used for communication control with the sample bin controller 10 and with the sample management subsystem 30 and the hospital information subsystem 40.
In some embodiments, the sample compartment controller 10 and the analyzer master control 20 may be integrated together to form an integrated controller for the sample analyzer, which can fully utilize the space of the PCB circuit board and fully utilize the working performance of the related circuit components.
Example four,
The embodiment discloses a sample analysis method of a sample analyzer.
In this embodiment, the sample analyzer is the sample analyzer disclosed in the second embodiment, and referring to fig. 3 and 12, the sample analyzer includes a closed sample chamber, in which a sample accommodating part 200, a detecting part 300, a sample transfer part 100, an active rotation part 400, and a sample scanning part are disposed, wherein the sample accommodating part 200 has a first hole site 210 for accommodating a first sample container Q1, and a second hole site 220 for accommodating a second sample container Q2.
In this embodiment, the sample analysis method is applied to the sample bin controller 10 and the analyzer main controller 20 in the third embodiment, and corresponding functions are implemented when the sample bin controller 10 and the analyzer main controller 20 execute the sample analysis method.
In one embodiment, referring to fig. 21, the sample analysis method includes the following steps:
(1) a judging step: the sample types of sample injection in the closed sample injection bin are obtained by detecting whether a sample container is placed in the first hole site 210 or the second hole site 220, and the sample types are divided into a first sample and a second sample. For example, as shown in fig. 8 to 11, when the elastic piece 303 of the micro switch 304 is not pressed down, the micro switch 304 does not generate a trigger signal, and the sample chamber controller 10 detects that the first hole site 210 is activated and the first sample container Q1 containing the first sample is placed because the trigger signal is not received; when the elastic piece 303 of the micro switch 304 is pressed, the micro switch 304 generates a trigger signal, and the sample chamber controller 10 receives the trigger signal and detects that the second hole site 220 is activated and the second sample container Q2 containing the second sample is placed in the second hole site; at this time, the sample chamber controller 10 can obtain whether the first sample or the second sample is fed into the closed sample feeding chamber.
Here, the first sample may be a peripheral blood sample (or a trace blood sample) of a human body, and the second sample may be a whole blood sample of a human body.
(2) A transfer step: the first well 210 in which the first sample container Q1 is placed or the second well 220 in which the second sample container Q2 is placed is transferred to a scanning position so that the sample scanning means 600 performs label scanning of the sample containers in the well. For example, referring to fig. 3 and fig. 20, the sample chamber controller 10 sends a motor driving signal to the sample transfer unit 100, so as to drive the sample transfer unit 100 to drive the sample accommodating unit 200 to move, and further enable the first hole site 210 or the second hole site 220 to reach the scanning position.
(3) A scanning step: and performing label scanning on the first sample container Q1 or the second sample container Q2 in the scanning position to obtain corresponding sample information. For example, in fig. 3 and 20, when the second sample container Q2 is placed in the second hole site 220 and is in the scanning position, the sample chamber controller 10 sends a scanning driving signal to the sample scanning unit 600 to drive the sample scanning unit 600 to scan the second sample cup Q2 for labels.
(4) A sampling step: the sampling needle samples from the first sample container Q2 or the second sample container Q3. For example, in fig. 2, fig. 3 and fig. 20, after the sample bin controller 10 obtains the sample information of the second sample, the motor driving signal is sent to the sample transfer unit 100, so that the sample transfer unit 100 is driven to drive the sample accommodating unit 200 to move, and the second hole 220 reaches the sampling position, and then the analyzer main control 20 sends the sampling driving signal to the sampling mechanism 900, so that the sampling needle 901 is inserted into the second sample container Q2 at the sampling position, thereby completing sampling of the second sample.
(5) A detection step: and detecting the collected sample to obtain a detection result. For example, as shown in fig. 20, the analyzer main controller 20 controls each detection component to perform corresponding work, so as to perform chemical detection, microscopic examination, and other processing on the sample sucked by the sampling needle, thereby obtaining detection information of the sample. The detection signal includes one or more detection indexes and result values of the sample.
Further, after the scanning step and before the sampling step, a sample type determining step is further included, referring to fig. 22, the sample type determining step includes: judging whether the type of the detected sample is consistent with the sample information obtained by scanning, if so, transferring a first hole site provided with a first sample container or a second hole site provided with a second sample container to a sampling site so as to sample; otherwise, alarm information is output.
Referring to fig. 2, fig. 3 and fig. 20, after the first sample container Q1 is placed in the first hole site 210, the sample bin controller 10 will transfer the first hole site 210 to the scanning site, so as to scan the sample information of the first sample, and at this time, the sample bin controller 10 determines that the type of the obtained sample is consistent with the sample information, which indicates that the sample introduction is normal. If the second sample container Q2 is misplaced in the first hole site 210, the sample information of the second sample is obtained by scanning, and at this time, the sample bin controller 10 judges that the obtained sample type is inconsistent with the sample information, indicating that the sample introduction is wrong, and outputting alarm information. The alarm information can be output in the modes of sound, light, characters, symbols and the like without strict limitation.
Further, a step of discharging the bin is also included after the above sampling step, and referring to fig. 22, since there is no time sequence relationship between the step of discharging the bin and the step of detecting, the step of discharging the bin and the step of detecting can be performed simultaneously. The warehouse-out step specifically comprises: and transferring the first hole site with the first sample container or the second hole site with the second sample container to a warehouse outlet site, and opening a warehouse door for sealing the sample inlet warehouse. For example, in fig. 2 and fig. 20, after the first sample container Q1 is sampled by the sampling needle 901, the sample chamber controller 10 moves the first hole site 210 to the output position (i.e., the position where the user can manually put in or take out the sample container), and then opens the chamber door 105 that closes the sample chamber, so that the user can take out the first sample container Q1 that has been sampled completely.
In an embodiment, there may be a case where the label cannot be scanned in the above scanning step, and to ensure the effectiveness of the scanning process, the scanning step may be performed by rotating in the forward direction and the reverse direction. Referring to fig. 2, 3, 20 and 23, the sample compartment controller 10 first drives the active rotary member 400 to perform one-directional rotation, thereby rotating the first sample container Q1 or the second sample container Q2 in the scanning position in the forward direction, and drives the sample scanning member 600 to perform label scanning during the rotation of the first sample container Q1 or the second sample container Q2; the sample container controller 10 determines whether or not sample information is obtained by scanning when the first sample container Q1 or the second sample container Q2 in the scanning position rotates forward one or more times, records the sample information if the sample information is obtained by scanning, and otherwise controls the sample container to rotate in the reverse direction. If the sample magazine controller 10 does not obtain the sample information by the forward rotation of the sample container, the active rotation member 400 is driven to perform the other rotation, thereby reversely rotating the first sample container Q1 or the second sample container Q2 in the scanning position and performing the label scanning during the reverse rotation of the first sample container Q1 or the second sample container Q2. The sample bin controller 10 continuously determines whether sample information is obtained by scanning when the first sample container Q1 or the second sample container Q2 at the scanning position rotates in the opposite direction for one or more times, records the sample information if the sample information is obtained by scanning, and outputs corresponding prompt information if the sample information is not obtained by scanning. For example, the sample bin controller 10 may output a prompt that a sample container is not placed and a sample container is not labeled.
In an embodiment, in the above scanning step, in order to determine validity of sample information obtained by scanning, a step of determining validity of information is further included, which specifically includes: scanning the label of the first sample container or the second sample container at the scanning position to obtain the identification code of the label; inquiring sample information corresponding to the identification code in a hospital information system to obtain sample information of a first sample in a first sample container or sample information of a second sample in a second sample container; if the sample information corresponding to the identification code cannot be inquired in the hospital information system, outputting corresponding prompt information, and providing an option for the user to select whether to continue detection.
For example, as shown in fig. 2, fig. 3, fig. 19 and fig. 24, the analyzer main control 20 obtains sample information from the sample bin controller 10, the analyzer main control 20 queries whether corresponding sample information exists in the hospital information subsystem 40, if the corresponding sample information exists, it indicates that a sample currently fed into the closed sample feeding bin is valid, and then the currently fed sample is detected according to a measurement mode corresponding to the sample information recorded by the hospital information system; if there is no corresponding sample information, the analyzer main control 20 outputs a corresponding prompt message, such as a user selection whether to continue the measurement. If the user selects to continue the detection, the currently-fed sample is indicated to be invalid, and a corresponding detection mode is not set, and at this time, some detection modes can be provided for the user to select, so that the analyzer main control 20 can subsequently detect the currently-fed sample according to the detection mode selected by the user; if the user does not choose to continue testing, indicating that the user is ready to forgo testing the currently fed sample, the sample bin controller 10 now transfers the sample container to the discharge location and opens the bin gate for the user to take the sample container out in time.
Those skilled in the art will appreciate that all or part of the functions of the various methods in the above embodiments may be implemented by hardware, or may be implemented by computer programs. When all or part of the functions of the above embodiments are implemented by a computer program, the program may be stored in a computer-readable storage medium, and the storage medium may include: a read only memory, a random access memory, a magnetic disk, an optical disk, a hard disk, etc., and the program is executed by a computer to realize the above functions. For example, the program may be stored in a memory of the device, and when the program in the memory is executed by the processor, all or part of the functions described above may be implemented. In addition, when all or part of the functions in the above embodiments are implemented by a computer program, the program may be stored in a storage medium such as a server, another computer, a magnetic disk, an optical disk, a flash disk, or a removable hard disk, and may be downloaded or copied to a memory of a local device, or may be version-updated in a system of the local device, and when the program in the memory is executed by a processor, all or part of the functions in the above embodiments may be implemented.
The present invention has been described in terms of specific examples, which are provided to aid understanding of the invention and are not intended to be limiting. For a person skilled in the art to which the invention pertains, several simple deductions, modifications or substitutions may be made according to the idea of the invention.

Claims (30)

1. A sample analyzer is characterized by comprising a closed sample feeding bin and a sampling mechanism, wherein a sample accommodating part, a sample feeding transfer part, an active rotating part and a sample scanning part are arranged in the closed sample feeding bin;
the sampling mechanism comprises a sampling needle for aspirating a sample from a sample container in a sampling position;
the sample accommodating part is provided with a hole for accommodating a sample container of a peripheral blood sample, and an elastic bearing assembly for providing a supporting height and a buffering stroke for the sample container of the peripheral blood sample is arranged in the hole;
the sample introduction transfer part is used for moving the sample container to enable the hole position of the sample container to reach the scanning position corresponding to the sample scanning part or reach the sampling position corresponding to the sampling mechanism;
the active rotating part is used for driving the sample container arranged in the hole site on the sample containing part to rotate;
the sample scanning component is used for scanning the label of the sample container at the scanning position and acquiring sample information of the peripheral blood sample.
2. The sample analyzer of claim 1 wherein the spring bearing assembly comprises a sliding bearing and a support spring;
the sliding bearing seat axially slides along the inner wall of the hole and is provided with an upper end surface and a lower end surface, and the upper end surface is used for bearing a sample container for containing the peripheral blood sample;
one end of the supporting spring is connected to the lower end face of the sliding bearing seat, and the other end of the supporting spring is connected to the bottom of the hole position;
the sliding bearing seat is used for elastically pushing the loaded sample container of the peripheral blood sample to a height matched with the sample sucking of the sampling needle under the action of the supporting spring; and reserving a buffer stroke for the sample container of the peripheral blood sample when the sampling needle is inserted into and abutting the sample container bottom of the peripheral blood sample.
3. The sample analyzer of claim 2 wherein the spring-in-socket assembly further comprises a base and a sliding rod;
the base is fixed at the bottom of the hole site, the upper surface of the base is provided with a slide rod channel, and the slide rod channel and the support spring are positioned on the same axis; the sliding rod penetrates through the supporting spring along the axis, one end of the sliding rod is connected to the lower end face of the sliding bearing seat, and the other end of the sliding rod penetrates into the sliding rod channel.
4. The sample analyzer of claim 1 wherein the sample container of the peripheral blood sample is adapted to fit into a cup adapter and be received within the well; the inside of the cup body adapter is provided with a cavity into which the sample container is inserted in a matching mode, and the outside of the cup body adapter is provided with a column structure which is inserted in the hole in a matching mode.
5. A sample analyzer is characterized by comprising a closed sample feeding bin, wherein a sample accommodating part, a driving rotating part and a sample scanning part are arranged in the closed sample feeding bin;
the sample accommodating part is provided with a first hole site of a first sample container for accommodating a first sample and a second hole site of a second sample container for accommodating a second sample;
the active rotating part is used for driving a first sample container to rotate when a first sample container containing a first sample is placed in the first hole, and driving a second sample container to rotate when a second sample container containing a second sample is placed in the second hole;
the sample scanning component is used for performing label scanning on the first sample container and the second sample container and acquiring sample information of the first sample and the second sample.
6. The sample analyzer as claimed in claim 5, wherein a detecting component is further disposed in the closed sample chamber, the detecting component is configured to determine a type of sample injected from the closed sample chamber when a sample container is placed in the closed sample chamber, and the type of sample is divided into a first sample and a second sample.
7. The sample analyzer of claim 6 wherein the detection component comprises a stop component and a sensing component;
the limiting assembly is movably connected to the sample accommodating part and used for limiting the first hole site from being placed into the first sample container or limiting the second hole site from being placed into the second sample container;
the induction component is arranged in the movable area of the limiting component and used for inducing the limiting state of the limiting component aiming at the first hole site or the second hole site and determining the sample type of the closed sample feeding bin according to the limiting state.
8. The sample analyzer of claim 6, wherein the sample information includes a sample type; the sample analyzer also comprises a controller, wherein the controller is used for judging whether the type of the sample detected by the detection component is consistent with the type of the sample scanned by the sample scanning component, and if not, alarming information is output.
9. The sample analyzer of claim 6, wherein the closed sample compartment further comprises a sample transfer component coupled to the sample receiving component; the sample introduction transfer part is used for transferring the position of the sample containing part;
the sample analyzer further comprises a controller, the controller is used for transferring the sample accommodating part through the sample transferring part after the detection part detects and determines the type of the sample injected from the closed sample injection bin, so that a first hole position corresponding to the type of the sample and provided with the first sample container is positioned at a scanning position, or a second hole position corresponding to the type of the sample and provided with the second sample container is positioned at the scanning position;
the sample scanning component performing label scanning on the first sample container and the second sample container comprises: performing a label scan on the first sample container in a scan position, or the second sample container in a scan position.
10. The sample analyzer of claim 5, wherein the closed sample compartment further comprises a sample transfer component coupled to the sample receiving component; the sample introduction transfer part is used for transferring the position of the sample containing part; a scanning position is arranged on the transfer track of the sample accommodating part; the active rotating component is arranged on one side of the scanning position and drives the first sample container or the second sample container in the scanning position to rotate; the sample scanning component is arranged on the other side of the scanning position, and the sample scanning component scans the first sample container or the second sample container in the scanning position for labels.
11. The sample analyzer of claim 5 wherein the enclosed sample compartment further comprises a sample transfer member coupled to the sample receiving member and the active rotation member; the sample introduction transfer part is used for simultaneously transferring the positions of the sample accommodating part and the active rotating part; a scanning position is arranged on the transfer track of the sample accommodating part and the active rotating part; the sample scanning component is disposed on one side of the scanning position, and the sample scanning component scans the first sample container or the second sample container in the scanning position for a label.
12. The sample analyzer of claim 10, wherein the closed sample chamber further comprises an elastic plunger member and two self-resetting pressing members respectively disposed corresponding to the first hole site and the second hole site; the self-resetting pressing part is movably arranged on the sample accommodating part; the elastic plunger part is arranged on the other side of the scanning position and used for elastically pushing the corresponding self-resetting pressing part to press the sample container in the corresponding hole site when the sample container in the first hole site or the second hole site reaches the scanning position, so that the first sample container or the second sample container can stably rotate under the driving of the driving rotating part.
13. The sample analyzer of claim 12 wherein the self-resetting hold-down component comprises a support, a hold-down portion, and a return spring; the support piece is fixed on the sample accommodating part and close to the corresponding hole site, and the pressing part is arranged on the support piece in a sliding manner and is used for abutting against the side surface of the sample container in the corresponding hole site; and two ends of the reset spring are respectively fixed on the pressing part and the supporting part and used for resetting the pressing part.
14. The sample analyzer of claim 13, wherein the head of the compressing portion is provided with two co-planar pulleys for engaging and abutting against the side of the first sample container or the second sample container to compress the sample container and being rotatable with the first sample container or the second sample container.
15. The sample analyzer of claim 14 wherein the resilient plunger member comprises a indenter mount and a resilient indenter;
the tail part of the pressing part is provided with a sliding surface; the sliding surface is inclined relative to a transfer trajectory along which the sample accommodating member is transferred; the pressure head seat is fixed on the other side of the scanning position, and the elastic pressure head is assembled on the pressure head seat through a compression spring; the end part of the elastic pressure head is positioned on the transfer track of the sliding surface, and the elastic pressure head is used for gradually pushing the pressing part to press the corresponding sampling cup by changing the collision position of the elastic pressure head and the sliding surface in the process that the first sample container or the second sample container moves to the scanning position.
16. The sample analyzer of claim 10 wherein the active rotation component includes a rotating wheel and a first motor for powering the rotating wheel;
the rotating wheel is arranged on one side of the scanning position, and the outer diameter edge of the rotating wheel is used for being in contact with the side face of the first sample container or the second sample container in the scanning position; the rotating wheel drives the contacted sample container to rotate through the rotation of the rotating wheel.
17. The sample analyzer of claim 11 wherein the active rotation component comprises a first guide bar, a second guide bar, and a second motor;
the first guide rod is arranged at the bottom of the first hole site, and a bearing part for bearing a first sample container in the first hole site is formed at the top end of the first guide rod;
the second guide rod is arranged at the bottom of the second hole site, and a bearing part for bearing a second sample container in the second hole site is formed at the top end of the second guide rod;
the second motor is in transmission connection with the first guide rod and the second guide rod and is used for driving the first guide rod or the second guide rod to rotate so as to drive the first sample container and the second sample container which are carried by the first guide rod or the second guide rod to rotate.
18. The sample analyzer of claim 5 wherein the first sample container of the first sample is adapted to fit into a cup adapter and be received in the first aperture location; the cup body adapter is internally provided with a chamber into which a first sample container of the first sample is inserted, and the cup body adapter is externally provided with a column structure which is inserted into the first hole site.
19. The sample analyzer of claim 18, wherein the side of the cup adapter has a plurality of ribs with voids formed between adjacent ribs that communicate with the interior chamber, each void having a width greater than a width of a label affixed to the side of the first sample container.
20. The sample analyzer of claim 18, wherein the cup adapter is transparent at least at locations corresponding to labels affixed to the side of the first sample container.
21. A sample analyzer is characterized by comprising a closed sample feeding bin, wherein a sample accommodating part, a sample feeding transfer part and a sample scanning part are arranged in the closed sample feeding bin;
the sample accommodating member is provided with a first hole site of a first sample container for accommodating a first sample, and a second hole site of a second sample container for accommodating a second sample;
the sample introduction transfer part is used for driving the first sample container to move from a placing position for receiving the first sample to a scanning position for scanning the first sample when the first sample container for containing the first sample is placed at the first hole site, and driving the second sample container to move from a placing position for receiving the second sample to a scanning position for scanning the second sample when the second sample container for containing the second sample is placed at the second hole site;
the sample scanning component is configured to scan the first sample container when the first sample container is transported to a scanning position and to scan the second sample container when the second sample container is transported to a scanning position.
22. The sample analyzer as claimed in claim 21, wherein the closed sample chamber is further provided with a detecting component for determining a type of sample injected from the closed sample chamber when the closed sample chamber has a sample container, and the type of sample is divided into two types of first sample and second sample.
23. The sample analyzer of claim 21, wherein the closed sample compartment further comprises an active rotation component; the active rotating component is arranged on one side of the scanning position and drives the first sample container or the second sample container in the scanning position to rotate; the sample scanning component is arranged on the other side of the scanning position, and the sample scanning component scans the first sample container or the second sample container in the scanning position for labels.
24. The sample analyzer of claim 21, wherein the closed sample compartment further comprises an active rotation component; the active rotating part is arranged on the sample accommodating part and is used for bearing a first sample container placed in the first hole site and a second sample container placed in the second hole site and driving the borne first sample container and/or second sample container to rotate; the sample scanning component is disposed on one side of the scanning position, and the sample scanning component scans the first sample container or the second sample container in the scanning position for a label.
25. A sample analysis method of a sample analyzer comprises a closed sample feeding bin, wherein a first hole site of a first sample container for containing a first sample and a second hole site of a second sample container for containing a second sample are arranged in the closed sample feeding bin; characterized in that the method comprises:
obtaining the sample type of sample injection in the closed sample injection bin by detecting whether a sample container is placed in the first hole site or the second hole site; the sample types are divided into a first sample and a second sample;
transferring the first hole site where the first sample container is placed or the second hole site where the second sample container is placed to a scanning site;
performing label scanning on the first sample container or the second sample container at the scanning position to obtain corresponding sample information;
a sampling needle samples from the first sample container or the second sample container;
and detecting the collected sample to obtain a detection result.
26. The method of claim 25, wherein after the label scanning of the first sample container or the second sample container in the scan position, prior to sampling from the first sample container or the second sample container, further comprising:
judging whether the type of the detected sample is consistent with the sample information obtained by scanning, if so, transferring a first hole site provided with the first sample container or a second hole site provided with the second sample container to a sampling position so as to sample; otherwise, alarm information is output.
27. The method of claim 25, wherein after sampling from the first sample container or the second sample container, further comprising: and transferring the first hole site where the first sample container is placed or the second hole site where the second sample container is placed to a bin outlet site, and opening a bin door of the closed sample feeding bin.
28. The method of claim 25, wherein said label scanning the sample container at the scan location to obtain corresponding sample information comprises:
rotating the first or second sample container in the scanning position and performing label scanning during rotation of the first or second sample container;
if the sample information is obtained by scanning, recording the sample information; if the sample information is not obtained by scanning, controlling the first sample container or the second sample container to rotate in the opposite direction, and scanning a label in the process of rotating the first sample container or the second sample container in the opposite direction;
if the sample information is obtained by scanning in the reverse rotation, recording the sample information; and if the sample information is not obtained by scanning in the reverse rotation, outputting corresponding prompt information.
29. The method of claim 25, wherein performing a label scan on a sample container at the scan bit to obtain corresponding sample information comprises:
performing label scanning on the first sample container or the second sample container at the scanning position to obtain an identification code of the label;
and inquiring sample information corresponding to the identification code in a hospital information system to obtain sample information of a first sample in the first sample container or sample information of a second sample in the second sample container.
30. The method of claim 29, wherein if sample information corresponding to the identification code is not queried in the hospital information system, outputting corresponding prompt information and providing an option for a user to select whether to continue the detection.
CN202011111130.4A 2020-10-16 2020-10-16 Sample analyzer and sample analysis method thereof Pending CN114384258A (en)

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CN202011111130.4A CN114384258A (en) 2020-10-16 2020-10-16 Sample analyzer and sample analysis method thereof

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Application Number Priority Date Filing Date Title
CN202011111130.4A CN114384258A (en) 2020-10-16 2020-10-16 Sample analyzer and sample analysis method thereof

Publications (1)

Publication Number Publication Date
CN114384258A true CN114384258A (en) 2022-04-22

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