CN114304466A - An experimental microwave sterilization device and sterilization method - Google Patents
An experimental microwave sterilization device and sterilization method Download PDFInfo
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- 230000001954 sterilising effect Effects 0.000 title claims abstract description 77
- 238000004659 sterilization and disinfection Methods 0.000 title claims abstract description 69
- 238000000034 method Methods 0.000 title claims abstract description 19
- 239000012530 fluid Substances 0.000 claims abstract description 57
- 238000010438 heat treatment Methods 0.000 claims abstract description 18
- 239000007788 liquid Substances 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 235000013305 food Nutrition 0.000 claims description 6
- 238000004140 cleaning Methods 0.000 claims description 5
- 239000004696 Poly ether ether ketone Substances 0.000 claims description 3
- 230000035515 penetration Effects 0.000 claims description 3
- 229920002530 polyetherether ketone Polymers 0.000 claims description 3
- 239000002861 polymer material Substances 0.000 claims description 3
- -1 polytetrafluoroethylene Polymers 0.000 claims description 3
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims description 2
- 239000004810 polytetrafluoroethylene Substances 0.000 claims description 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 229940127557 pharmaceutical product Drugs 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 8
- 238000012545 processing Methods 0.000 abstract description 5
- 239000000796 flavoring agent Substances 0.000 abstract description 4
- 235000019634 flavors Nutrition 0.000 abstract description 4
- 230000014759 maintenance of location Effects 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 description 6
- 238000009928 pasteurization Methods 0.000 description 6
- 235000013601 eggs Nutrition 0.000 description 5
- 239000003814 drug Substances 0.000 description 4
- 239000000084 colloidal system Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000003255 drug test Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000012827 research and development Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 235000021056 liquid food Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
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- 238000002360 preparation method Methods 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
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Abstract
本发明提供一种实验型微波杀菌装置，用于少量流体的杀菌，包括微波加热腔，在所述微波加热腔内设置用于通过待杀菌流体的毛细管，并在所述微波加热腔的入口处和出口处设置毛细管入口和毛细管出口，所述毛细管入口与用于承装待杀菌流体的第一容器连接，所述毛细管出口与用于承装杀菌后的流体的第二容器连接，所述毛细管入口与所述第一容器之间还设置一流体泵；所述待杀菌流体的处理量小于100ml/min。本发明提供的一种实验型微波杀菌装置和杀菌方法，适合于小量流体杀菌的方法，利用微波杀菌的热效应和非热效应，在相对较低的温度下利用微波对流体进行杀菌，减少流体中热敏性成分的损失，更好的保持流体的风味和胶体界面特性。
The invention provides an experimental microwave sterilization device for sterilizing a small amount of fluid, comprising a microwave heating chamber, a capillary tube for passing the fluid to be sterilized is arranged in the microwave heating chamber, and at the entrance of the microwave heating chamber A capillary inlet and a capillary outlet are provided at the outlet and the capillary inlet, the capillary inlet is connected with the first container for holding the fluid to be sterilized, the capillary outlet is connected with the second container for holding the sterilized fluid, the capillary A fluid pump is also arranged between the inlet and the first container; the processing capacity of the fluid to be sterilized is less than 100ml/min. An experimental microwave sterilization device and a sterilization method provided by the invention are suitable for a method of sterilizing a small amount of fluid. The thermal effect and non-thermal effect of microwave sterilization are utilized to sterilize the fluid at a relatively low temperature by using microwaves to reduce the amount of fluid in the fluid. Loss of heat-sensitive components, better retention of fluid flavor and colloidal interface properties.
Description
技术领域technical field
本发明属于流体食品药品生产研发技术领域，尤其涉及一种实验型微波杀菌装置和杀菌方法。The invention belongs to the technical field of fluid food and drug production research and development, in particular to an experimental microwave sterilization device and a sterilization method.
背景技术Background technique
流体食品药品在灌装前，通常需要对其进行杀菌处理。现有的方法是采用高温瞬时杀菌、巴氏杀菌等来处理流体。该方法中，流体保持高温的时间相对较长，且流体承受的温度也相对较高。会对流体中的热敏性成分造成较大的损失，影响产品的风味及胶体界面特性。Liquid food and medicine usually need to be sterilized before being filled. The existing method is to use high temperature flash sterilization, pasteurization, etc. to treat the fluid. In this method, the fluid is kept at a high temperature for a relatively long time, and the temperature the fluid is subjected to is relatively high. It will cause a large loss of heat-sensitive components in the fluid, affecting the flavor and colloid interface characteristics of the product.
对于常用的巴氏杀菌，比如巴杀液蛋，现在普遍的杀菌装置，基本都采用蛋液与热水之间进行热传导的方式来进行杀菌。对蛋液进行巴氏杀菌的热水，需要在3个大气压下被加热到135℃，才能达到有效的杀菌效果。并且加热效果不均匀，保证中心蛋液充分灭菌时，外周蛋液的品质下降，因此常常难以达到完全加热杀菌的目的。加热完毕的热水又需要重新加热才能进行重新使用。大量热水的使用，既浪费了资源，又容易造成意外。For commonly used pasteurization, such as liquid pasteurized eggs, the current common sterilization devices basically use heat conduction between egg liquid and hot water for sterilization. The hot water for pasteurizing egg liquid needs to be heated to 135°C under 3 atmospheres to achieve effective sterilization effect. In addition, the heating effect is uneven, and when the central egg liquid is fully sterilized, the quality of the peripheral egg liquid decreases, so it is often difficult to achieve the purpose of complete heating and sterilization. The heated hot water needs to be reheated before it can be reused. The use of a large amount of hot water not only wastes resources, but also easily causes accidents.
对于流体常用的超高温瞬时灭菌，现有的设备同样具有上述巴氏杀菌缺陷，同时因设备制造利用热传导原理，难以实现小型化，目前实验型设备最小需要的样品量也约4-5L，这对于实验室研发而言，尤其是流体组成含有高价值组分或尚难于大批量商业化的组分而言，几乎是难以逾越的瓶颈，致使很多流体食品、药品的商业开发或实验样品制备在该灭菌环节卡壳。For the commonly used ultra-high temperature instantaneous sterilization of fluids, the existing equipment also has the above-mentioned pasteurization defects. At the same time, it is difficult to achieve miniaturization due to the principle of heat conduction in equipment manufacturing. At present, the minimum sample volume required for experimental equipment is about 4-5L. This is an almost insurmountable bottleneck for laboratory research and development, especially for the components whose fluid composition contains high-value components or is difficult to commercialize in large quantities, resulting in the commercial development of many fluid foods, pharmaceuticals or experimental sample preparation. Stuck in this sterilization link.
发明内容SUMMARY OF THE INVENTION
鉴于此，本发明的目的在于提供一种实验型微波杀菌装置和杀菌方法，解决了现有实验型杀菌装置的最小样品处理量不能满足含有高价值组分或尚难于大批量商业化的组分的技术问题。In view of this, the purpose of the present invention is to provide an experimental microwave sterilization device and a sterilization method, which solves the problem that the minimum sample processing capacity of the existing experimental sterilization device cannot meet the requirements of high-value components or components that are difficult to commercialize in large quantities. technical issues.
第一个方面，本发明提供一种实验型微波杀菌装置，用于少量流体的杀菌，包括微波加热腔，在所述微波加热腔内设置用于通过待杀菌流体的毛细管，并在所述微波加热腔的入口处和出口处设置毛细管入口和毛细管出口，所述毛细管入口与用于承装待杀菌流体的第一容器连接，所述毛细管出口与用于承装杀菌后的流体的第二容器连接，所述毛细管入口与所述第一容器之间还设置一流体泵；所述待杀菌流体的处理量小于100ml/min。In a first aspect, the present invention provides an experimental microwave sterilization device for sterilizing a small amount of fluid, including a microwave heating chamber, a capillary tube for passing the fluid to be sterilized is arranged in the microwave heating chamber, and the microwave The inlet and outlet of the heating chamber are provided with a capillary inlet and a capillary outlet, the capillary inlet is connected with the first container for holding the fluid to be sterilized, and the capillary outlet is used for holding the sterilized fluid. The second container A fluid pump is also arranged between the capillary inlet and the first container; the processing capacity of the fluid to be sterilized is less than 100ml/min.
优选地，所述毛细管为内径小于微波穿透深度的毛细管。Preferably, the capillary is a capillary with an inner diameter smaller than the penetration depth of microwaves.
优选地，所述毛细管的材质为耐高温耐高压的高分子材料，包括聚醚醚酮、聚四氟乙烯。Preferably, the material of the capillary is a high temperature and high pressure resistant polymer material, including polyether ether ketone and polytetrafluoroethylene.
优选地，所述毛细管为长度为500-2000mm、直径为150-200mm的螺旋设置的盘管。Preferably, the capillary is a coiled tube with a length of 500-2000 mm and a diameter of 150-200 mm.
优选地，所述流体泵为精密恒流泵，所述精密恒流泵的最高承压为10MPa，流速为0.1-100mL/min。Preferably, the fluid pump is a precision constant-flow pump, the maximum pressure of the precision constant-flow pump is 10 MPa, and the flow rate is 0.1-100 mL/min.
第二个方面，本发明还提供一种基于如上所述的实验型微波杀菌装置的杀菌方法，将置于第一容器内的待杀菌流体通过连接了毛细管的流体泵输送至微波加热腔中进行微波杀菌，并收集于第二容器中。In a second aspect, the present invention also provides a sterilization method based on the above-mentioned experimental microwave sterilization device. Microwave sterilized and collected in a second container.
优选地，在进行杀菌之前或杀菌之后，用水或消毒液运行进行消毒清洗。Preferably, before sterilization or after sterilization, sterilization cleaning is performed by running with water or a sterilizing solution.
第三个方面，本发明还提供一种如上所述的实验型微波杀菌装置在流体食品药品测试中的应用。In a third aspect, the present invention also provides an application of the above-mentioned experimental microwave sterilization device in fluid food and drug testing.
与现有技术相比，本发明的有益效果为：Compared with the prior art, the beneficial effects of the present invention are:
(1)本发明提供的一种实验型微波杀菌装置和杀菌方法，适合于小量流体杀菌的方法，利用微波杀菌的热效应和非热效应，在相对较低的温度下利用微波对流体进行杀菌，减少流体中热敏性成分的损失，更好的保持流体的风味和胶体界面特性。(1) An experimental microwave sterilization device and sterilization method provided by the present invention are suitable for a method for sterilizing a small amount of fluid, utilizing the thermal effect and non-thermal effect of microwave sterilization, and utilizing microwaves to sterilize the fluid at a relatively low temperature, Reduce the loss of heat-sensitive components in the fluid, and better maintain the flavor and colloid interface properties of the fluid.
(2)该杀菌方法样品需要量小、可降低杀菌温度，可广泛适用于巴氏杀菌、高温杀菌、超高温瞬时杀菌等多种需要。(2) The sterilization method requires a small amount of samples, can reduce the sterilization temperature, and can be widely used in various needs such as pasteurization, high temperature sterilization, and ultra-high temperature instantaneous sterilization.
(3)该杀菌装置具有样品需要量小、可制造难度小、制造成本低、运行成本低、清洗简单、一机多用等优点。(3) The sterilization device has the advantages of small sample demand, low manufacturing difficulty, low manufacturing cost, low operating cost, simple cleaning, and multiple uses in one machine.
附图说明Description of drawings
图1为本发明涉及的一种实验型微波杀菌装置的结构示意图。FIG. 1 is a schematic structural diagram of an experimental microwave sterilization device involved in the present invention.
具体实施方式Detailed ways
以下结合附图和下述实施方式进一步说明本发明，应理解，附图和下述实施方式仅用于说明本发明，而非限制本发明。The present invention will be further described below with reference to the accompanying drawings and the following embodiments. It should be understood that the accompanying drawings and the following embodiments are only used to illustrate the present invention, but not to limit the present invention.
本发明提供一种实验型微波杀菌装置，用于少量流体的杀菌，包括微波加热腔5，在所述微波加热腔5内设置用于通过待杀菌流体的毛细管3，并在所述微波加热腔5的入口处和出口处设置毛细管入口8和毛细管出口9，所述毛细管入口8与用于承装待杀菌流体的第一容器2连接，所述毛细管出口9与用于承装杀菌后的流体的第二容器7连接，所述毛细管入口8与所述第一容器2之间还设置一流体泵4；所述待杀菌流体的处理量小于100ml/min。The present invention provides an experimental microwave sterilization device for sterilizing a small amount of fluid, comprising a
在一个实施例中，为确保待杀菌流体的处理量足够小，所述毛细管为内径小于微波穿透深度的毛细管，材质可以为耐高温耐高压的高分子材料，例如聚醚醚酮、聚四氟乙烯。所述毛细管可以为长度为500-2000mm、直径为150-200mm的螺旋设置的盘管。In one embodiment, in order to ensure that the processing volume of the fluid to be sterilized is small enough, the capillary is a capillary with an inner diameter smaller than the microwave penetration depth, and the material can be a high temperature and high pressure resistant polymer material, such as polyetheretherketone, polytetrafluoroethylene vinyl fluoride. The capillary tube may be a coiled tube with a length of 500-2000 mm and a diameter of 150-200 mm.
在一个实施例中，所述流体泵可以为精密恒流泵，所述精密恒流泵的最高承压为10MPa，流速为0.1-100mL/min。In one embodiment, the fluid pump may be a precision constant-flow pump, the maximum pressure of the precision constant-flow pump is 10 MPa, and the flow rate is 0.1-100 mL/min.
在一个实施例中，所述第一容器2置于超净工作台1中，所述第二容器7置于超净工作台6中。在另一个实施例中，所述微波杀菌装置可以集成在超净工作台内(1，6)，也可固定在超净工作台旁(1，6)，也可通过置于滑轮的支架上，用于使用时推至超净工作台旁(1，6)。In one embodiment, the
本发明提供的一种实验型微波杀菌装置，综合交叉应用微流体技术、微波加热原理、食品药品灭菌机理，通过精密恒流泵保证液体在微波加热腔内准确的停留时间；通过微波穿透深度大于内径的耐高温耐压高分子毛细管输送流体，保证流体全部直接被微波辐射；通过毛细管管路在微波腔内盘管长度，来配合恒流泵获取在腔内不同的杀菌时间，用于不同的杀菌需要。An experimental microwave sterilization device provided by the invention comprehensively and cross-applies microfluidic technology, microwave heating principle, and food and drug sterilization mechanism, and ensures the accurate residence time of liquid in the microwave heating cavity through a precision constant current pump; The high temperature and pressure resistant polymer capillary with a depth greater than the inner diameter transports the fluid to ensure that the fluid is directly irradiated by microwaves; the length of the coiled tube in the microwave cavity through the capillary pipeline is used to cooperate with the constant current pump to obtain different sterilization times in the cavity. Different sterilization needs.
本发明还提供一种基于如上所述的实验型微波杀菌装置的杀菌方法，将置于第一容器2内的待杀菌流体通过连接了毛细管3的流体泵4输送至微波加热腔5中进行微波杀菌，并收集于第二容器7中。在进行杀菌之前或杀菌之后，用水或消毒液运行进行消毒清洗。The present invention also provides a sterilization method based on the above-mentioned experimental microwave sterilization device, in which the fluid to be sterilized placed in the
本发明提供的一种实验型微波杀菌装置和杀菌方法适用于流体食品药品测试中的巴氏杀菌、高温杀菌或超高温瞬时杀菌。The experimental microwave sterilization device and sterilization method provided by the invention are suitable for pasteurization, high temperature sterilization or ultra-high temperature instantaneous sterilization in fluid food and drug testing.
本发明提供的一种实验型微波杀菌装置和杀菌方法，适合于小量流体杀菌的方法，利用微波杀菌的热效应和非热效应，在相对较低的温度下利用微波对流体进行杀菌，减少流体中热敏性成分的损失，更好的保持流体的风味和胶体界面特性。该杀菌装置具有样品需要量小、可制造难度小、制造成本低、运行成本低、清洗简单、一机多用等优点。该杀菌方法样品需要量小、可降低杀菌温度，可广泛适用于巴氏杀菌、高温杀菌、超高温瞬时杀菌等多种需要。An experimental microwave sterilization device and a sterilization method provided by the invention are suitable for a method of sterilizing a small amount of fluid. The thermal effect and non-thermal effect of microwave sterilization are utilized to sterilize the fluid at a relatively low temperature by using microwaves, thereby reducing the amount of fluid in the fluid. Loss of heat-sensitive components, better retention of fluid flavor and colloidal interface properties. The sterilization device has the advantages of small demand for samples, low manufacturing difficulty, low manufacturing cost, low operating cost, simple cleaning, multi-purpose for one machine, and the like. The sterilization method requires a small amount of samples, can reduce the sterilization temperature, and can be widely applied to various needs such as pasteurization, high temperature sterilization, and ultra-high temperature instantaneous sterilization.
在不脱离本发明的基本特征的宗旨下，本发明可体现为多种形式，因此本发明中的实施形态是用于说明而非限制，由于本发明的范围由权利要求限定而非由说明书限定，而且落在权利要求界定的范围，或其界定的范围的等价范围内的所有变化都应理解为包括在权利要求书中。The present invention can be embodied in various forms without departing from the essential characteristics of the present invention. Therefore, the embodiments in the present invention are for illustration rather than limitation, since the scope of the present invention is defined by the claims rather than the description. , and all changes that come within the scope defined by the claims, or equivalents to the scope defined by the claims, should be construed as being included in the claims.
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| CN201160488Y (en) * | 2008-02-03 | 2008-12-10 | 王承辉 | Microwave sterilization machine for current medium |
| CN102989020A (en) * | 2012-12-12 | 2013-03-27 | 河南勃达微波设备有限责任公司 | Microwave fluid sterilizing equipment |
| CN103891883A (en) * | 2012-12-30 | 2014-07-02 | 上海沃迪自动化装备股份有限公司 | Experiment-type microwave ultrahigh-temperature instant sterilization equipment |
| CN112450351A (en) * | 2020-12-25 | 2021-03-09 | 沈阳泽嘉科技有限公司 | Liquid spiral tube microwave sterilization equipment and sterilization method using same |
| CN216874860U (en) * | 2022-01-13 | 2022-07-05 | 伊睦(上海)流体科技有限公司 | Experimental microwave sterilization device |
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- 2022-01-13 CN CN202210037052.0A patent/CN114304466A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201160488Y (en) * | 2008-02-03 | 2008-12-10 | 王承辉 | Microwave sterilization machine for current medium |
| CN102989020A (en) * | 2012-12-12 | 2013-03-27 | 河南勃达微波设备有限责任公司 | Microwave fluid sterilizing equipment |
| CN103891883A (en) * | 2012-12-30 | 2014-07-02 | 上海沃迪自动化装备股份有限公司 | Experiment-type microwave ultrahigh-temperature instant sterilization equipment |
| CN112450351A (en) * | 2020-12-25 | 2021-03-09 | 沈阳泽嘉科技有限公司 | Liquid spiral tube microwave sterilization equipment and sterilization method using same |
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