CN114288548A

CN114288548A - Implantable nerve stimulator suitable for four limbs of human body

Info

Publication number: CN114288548A
Application number: CN202111044517.7A
Authority: CN
Inventors: 张高龙; 王航; 马伯志; 郝红伟; 李路明
Original assignee: Tsinghua University; Beijing Pins Medical Co Ltd
Current assignee: Tsinghua University; Beijing Pins Medical Co Ltd
Priority date: 2021-09-07
Filing date: 2021-09-07
Publication date: 2022-04-08

Abstract

The invention provides an implanted nerve stimulator suitable for four limbs of a human body, which belongs to the technical field of medical instruments and comprises: the cylindrical end part, the shell part and the tail part are sequentially connected to form a cylindrical end part, a shell part and a tail part; a circuit board is arranged inside the shell component; a wireless charging coil is arranged in the end part, and the central axis of the wireless charging coil is parallel to the length direction of the shell part; an electrode connector for inserting an electrode is arranged in the tail part, and a connecting channel of the electrode connector is parallel to the length direction of the shell part; the implantable nerve stimulator optimizes the layout of internal components, thereby reducing the overall width and thickness of the nerve stimulation electrode and facilitating the implantation of the nerve stimulation electrode into four limbs of a human body.

Description

Implantable nerve stimulator suitable for four limbs of human body

Technical Field

The invention relates to the technical field of medical instruments, in particular to an implantable nerve stimulator suitable for four limbs of a human body.

Background

The implanted nerve stimulator is implanted into different positions inside human body to send electric pulse signal to specific tissue inside human body to treat or improve relevant diseases and symptoms.

Currently, there are areas of neuromodulation applications using implantable neurostimulators, mainly Deep Brain Stimulation (DBS), Vagus Nerve Stimulation (VNS), spinal (SCS) and Sacral (SNM), Tibial (TNS), and the diseases treated include: parkinson, epilepsy, pain, urinary retention, and the like.

Implant neural stimulator inevitably and cause the injury to the patient, according to implanting human different positions, miniaturize neural stimulator, can reduce the injury of implantation operation to the patient, reduce the operation degree of difficulty, promote the aesthetic property.

Disclosure of Invention

Therefore, the technical problem to be solved by the present invention is to overcome the defect that the implantable neurostimulators in the prior art are not miniaturized according to different positions implanted into the human body, so as to provide an implantable neurostimulator suitable for four limbs of the human body.

In order to solve the above technical problems, the present invention provides an implantable neurostimulator suitable for human limbs, comprising: the end part component, the shell component and the tail component which are connected in sequence to form a column shape;

a circuit board is arranged inside the shell component;

a wireless charging coil is arranged in the end part, and the central axis of the wireless charging coil is parallel to the length direction of the shell part;

an electrode connector used for inserting an electrode is arranged in the tail part, and the central axis of a connecting channel of the electrode connector is parallel to the length direction of the shell part.

Optionally, the housing component comprises: the shell comprises a shell, an end flange and a tail flange, wherein two ends of the shell are respectively connected with the end flange and the tail flange.

Optionally, the housing shell comprises: the circuit board is arranged close to the plane wall of the shell in the shell component, and the circuit board is arranged in parallel with the plane wall of the shell at intervals.

Optionally, the two ends of the housing shell are provided with detachable support brackets, and the inner walls of the support brackets are provided with support bosses for supporting the circuit board.

Optionally, the end flange and the tail flange are respectively provided with a mounting hole for mounting a feed-through component, and the wireless charging coil and the antenna are electrically connected with a circuit board inside the shell component through the feed-through component by connecting leads.

Optionally, the end part and the tail part are made of a polymer material.

Optionally, the end part and the tail part are cast molded using epoxy resin.

Optionally, one end of the electrode is fixed by snapping in the connection channel of the electrode connector.

Optionally, the electrode connector has an annular groove in the connection channel, and the electrode has an annular flange thereon adapted to snap into the annular groove.

Optionally, the end part and/or the tail part is/are provided with suture holes.

The technical scheme of the invention has the following advantages:

1. according to the implantable neural stimulator, the layout of internal components is optimized, so that the overall width and thickness of the neural stimulation electrode are reduced, and the neural stimulation electrode is conveniently implanted into four limbs of a human body; specifically, the end part, the shell part and the tail part are sequentially connected along the axial direction to form a column shape, so that the column shape is convenient to arrange in human tissues; in addition, an electrode connector is arranged in the tail part, and the electrode connector enables the electrode to be parallel to the length direction of the shell part, so that the electrode connector is beneficial to being implanted into limbs of a human body.

2. According to the implantable neural stimulator, in the end part component, the central shaft of the wireless charging coil is arranged in parallel with the length direction of the shell component, so that the wireless charging coil can be installed on the premise of not increasing the overall diameter of the neural stimulator; and, when charging through wireless charging coil, the accessible is established external equipment cover and is cooperated with wireless charging coil on human four limbs.

3. According to the implantable nerve stimulator provided by the invention, in the shell component, the battery and the electrical element are arranged on the circuit board in parallel, so that the diameter of the shell component is reduced, and the whole width and thickness of the nerve stimulation electrode are reduced.

4. According to the implantable nerve stimulator provided by the invention, the shell of the shell is provided with the plane wall, and the circuit board is arranged in parallel close to the plane wall in the first accommodating cavity of the shell component, so that the circuit board is arranged in the first accommodating cavity in an offset manner, and an electrical element and a battery are conveniently arranged on the circuit board, so that the space of the first accommodating cavity is utilized to the maximum extent, and the whole width and thickness of the nerve stimulating electrode are reduced.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.

Fig. 1 is a perspective view of an implantable neurostimulator provided in an embodiment of the present invention.

Fig. 2 is an exploded view of fig. 1.

Fig. 3 is a front sectional view of the electrode connector of fig. 2.

Fig. 4 is a perspective view of the electrode of fig. 3.

Fig. 5 is an exploded view of the housing components of fig. 2.

Fig. 6 is an enlarged view of the circuit board area of fig. 5.

Fig. 7 is a perspective view of the support bracket.

Fig. 8 is a perspective view of the end flange.

Fig. 9 is a rear perspective view of the end flange of fig. 8.

Fig. 10 is a perspective view of the tail flange.

Fig. 11 is a rear perspective view of the tail flange of fig. 10.

Fig. 12 is a perspective view of another embodiment of an implantable neurostimulator.

Description of reference numerals:

1. an end member; 2. a housing component; 3. an electrode; 4. an electrode connector; 5. sewing the hole; 6. a wireless charging coil; 7. an antenna; 8. a feedthrough means; 9. an annular groove; 10. an annular flange; 11. a housing shell; 12. a planar wall; 13. an arcuate wall; 14. a support bracket; 15. supporting the boss; 16. a first chuck structure; 17. a circuit board; 18. a card slot; 19. an end flange; 20. a tail flange; 21. mounting holes; 22. a step structure; 23. a battery; 24. an electrical component; 25. a tail member; 26. a second chuck structure; 27. a slot structure; 28. a connecting member; 29. an insulating ring; 30. connecting the contacts; 31. a canted coil spring; 32. a spring clamp groove; 33. a boss; 34. and limiting ribs.

Detailed Description

The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.

In addition, the technical features involved in the different embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.

The present embodiment provides an implantable neurostimulator, as shown in fig. 1, comprising: the end part 1, the shell component 2 and the tail component 25 are connected in sequence along a direction to form a column shape, so that the implantable nerve stimulator can be implanted to narrow parts such as limbs of a human body conveniently, and the direction can be called as the length direction of the implantable nerve stimulator. In addition, the outer wall surface of the cylinder formed by the combination of the end part 1, the shell part 2 and the tail part 25 is preferably an arc surface so as to facilitate the whole body to be implanted into human tissues. In addition, in order to fix the implantable neurostimulator on the human tissue, a suture hole 5 is arranged on the shell, in the embodiment, the suture hole 5 is arranged on the outer wall of the tail part 25, an electrode connector 4 is arranged at the end part of the tail part 25 and extends out, and the electrode connector 4 is used for connecting with the electrode 3, so that the neurostimulator in the human body is stimulated.

As shown in fig. 2, the housing member 2 is a uniform cylindrical member, a first accommodating cavity is formed in the housing member 2, a circuit board 17 is arranged in the first accommodating cavity, and a battery 23 and an electrical component 24 are arranged on the circuit board 17 in parallel; the arrangement optimizes the layout of internal components, thereby reducing the overall width and thickness of the nerve stimulation electrode 3 and facilitating the implantation in four limbs of a human body.

As shown in fig. 2, the end member 1 is connected to the head of the housing member 2, a second accommodating cavity is formed in the end member 1, a wireless charging coil 6 is arranged in the second accommodating cavity, the central axis of the wireless charging coil 6 is parallel to the length direction of the housing member 2, and the central axis of the wireless charging coil 6 is parallel to the length direction of the housing member 2, so that the wireless charging coil 6 can be installed without increasing the overall diameter of the nerve stimulation electrode 3; and, after implanting implanted neural stimulator along human four limbs length direction, the axial that is located wireless charging coil 6 of tip part 1 is parallel with human four limbs length direction to when charging through wireless charging coil 6, the accessible is established external equipment cover and is cooperated with wireless charging coil 6 on human four limbs. In addition, an antenna 7 is also arranged in the end part 1, and the offset space can be used for arranging the antenna 7 by arranging the wireless charging coil 6 and the shell part 2 eccentrically. The antenna 7 is arranged along one side of the wireless charging coil 6; the antenna 7 can be used for signal connection with an external device, specifically, can be connected through bluetooth, so as to realize signal interaction between the circuit board 17 and the external device. Preferably, the antenna 7 is bent back and forth along the circumference of the outer arc profile of the wireless charging coil 6 and extends along the axial direction of the wireless charging coil 6.

As shown in fig. 2, the tail member 25 is connected to the tail of the housing member 2, the tail member 25 has a third accommodating cavity therein, the electrode connector 4 is disposed in the third accommodating cavity, the electrode connector 4 is disposed parallel to the length direction of the housing member 2 and is preferably disposed coaxially with the cross-sectional centroid of the housing member 2, the electrode connector 4 is adapted to be inserted with the electrode 3, and the stimulation point of the electrode 3 is exposed out of the tail member 25; the electrode 3 is inserted into the electrode connector 4 to electrically connect the electrode 3 with the circuit board 17, so that nerve stimulation is performed on the human body through the electrode 3.

As shown in fig. 3 and 4, the electrode connector 4 includes a plurality of axially disposed connecting members 28. Each connector 28 is spaced apart by an insulating ring 29 to define a connecting passage. Each connection 28 is intended to be electrically connected correspondingly to a respective connection contact 30 of the electrode 3. Specifically, the connecting piece 28 is provided with a spring slot 32 for accommodating a bevel coil spring 31, and the connecting piece 28 is abutted and electrically connected with the connecting contact 30 of the electrode 3 through the bevel coil spring 31. In the present case, the connection contact 30 of the electrode 3 is fixed in the connection channel of the electrode connector 4 by means of a snap connection. Specifically, an annular flange 10 is provided on one of the connection contacts 30 of the electrode 3 remote from the electrode tip, an annular groove 9 is provided on the connection piece 28 at the top end of the electrode connector 4, so that a boss 33 abutting against the annular flange 10 is formed at the bottom end of the connection piece 28, one end of the annular flange 10 is snapped into the annular groove 9 and abuts against the boss 33, and the other end of the annular flange 10 is snapped by a coil spring 31 of the top end connection piece 28, so that the electrode connector 4 forms an axial fixation to the electrode 3. In the present application, the end of the electrode connector 4 near the stimulation end is referred to as the top end, and vice versa for the sake of convenience in description of the orientation. After one end of the electrode 3 is inserted into the electrode connector 4, the plurality of stimulation contacts on the other end of the electrode 3 are exposed out of the electrode connector 4, namely, out of the top cover main body, so as to stimulate the nerves of the human body.

As shown in fig. 5, the housing member 2 includes: housing shell 11, support brackets 14, end flanges 19 and tail flanges 20. Wherein, the end flange 19 and the tail flange 20 are respectively connected to two ends of the shell body 11, the outer sides of the end flange 19 and the tail flange 20 are respectively provided with a mounting hole 21 for mounting the feed-through 8, after the feed-through 8 is packaged on the mounting hole 21, the wireless charging coil 6, the antenna 7 and the electrode connector 4 are electrically connected with the circuit board 17 inside the shell body 2 through the feed-through 8 by connecting leads.

As shown in fig. 5, the main body of the housing shell 11 is made of a metal material, such as titanium, titanium alloy, stainless steel, etc., and the shell is coated with an insulating coating, such as parylene coating. The housing case 11 includes: a plane wall 12 and an arc-shaped wall 13, the circuit board 17 is disposed near the plane wall 12 of the housing shell 11 in the first accommodation chamber of the housing member 2, and the circuit board 17 is disposed in parallel with and spaced apart from the plane wall 12 of the housing shell 11. In the implantable neurostimulator provided by the embodiment, the arc-shaped wall 13 of the shell 11 can keep smooth contact with the tissues in the human body, the plane for installing the circuit board 17 is formed in the first accommodating cavity of the shell 11 through the plane wall 12 of the shell 11, the circuit board 17 is installed on the plane in parallel, and the components such as the electrical components 24, the battery 23 and the like can be conveniently arranged on the circuit board 17.

As shown in fig. 6, both ends of the housing shell 11 are detachably provided with support brackets 14, respectively. The support bracket 14 has an outer wall adapted to the inner wall of the housing shell 11, including a flat wall and a curved wall, which ensure relative fixation of the support bracket 14 and the housing shell 11 in the circumferential direction. The inner wall of the support bracket 14 has a support boss 15 for fixedly supporting the circuit board 17; specifically, the support boss 15 is a support protruding from an inner wall where a plane wall and an arc-shaped wall of the support bracket 14 meet. Preferably, the support bracket 14 is further provided with a limiting rib 34 inside. The limiting rib 34 is arranged at one end of the supporting bracket 17 and is arranged on part of the supporting boss 15. Correspondingly, the circuit board 17 is provided with a slot 18 which is matched with the limiting rib 34. During installation, the two support brackets 14 are oppositely arranged, one ends of the support brackets are provided with the limiting ribs 34, the limiting ribs 34 are clamped into the clamping grooves 28 at the two ends of the circuit board 17, the part of the circuit board 17 is inserted into the support brackets 14, the support bosses 15 are supported at the bottom ends of the part, inserted into the support brackets 14, of the circuit board 17, and therefore stable support of the circuit board 17 can be improved, and the length of the nerve stimulator can be further shortened. This application inserts circuit board 17 back in casing shell 11, and support bracket 14 through both ends is fixed with circuit board 17 joint to the equipment of circuit board 17 in casing shell 11 of being convenient for improves product packaging efficiency. In addition, a battery 23 and an electrical component 24 are connected to the circuit board 17, and the battery 23 and the electrical component 24 are arranged in parallel along the length direction of the housing member 2 to reduce the occupied space of the housing member 2.

As shown in fig. 7, the supporting bracket 14 has a second clamping structure 26 at the outer side of the end where the limiting rib 34 is arranged, and the second clamping structure 26 is used for being connected with the end flange 19 or the tail flange 20 in a plugging manner; the outer wall of the second catch formation 26 is shaped as a combination of an arc and a flat surface to ensure that the two connectors are circumferentially fixed relative to one another when the second catch formation 26 is inserted into the end flange 19 or the tail flange 20. The end flange 19 and the end flange 20 have outer walls adapted to the inner walls of the housing shell 11, including a flat wall and an arc wall, which ensure the relative fixation of the end flange 19, the end flange 20 and the housing shell 11 in the circumferential direction. On the sides of the end flange 19 and the rear flange 20 facing the support bracket 14, a slot structure 27 for insertion into the support bracket 14 is provided, and the support bracket 14 is inserted into the slot structure 27 by inserting the second locking structure 26 of the support bracket 14 into the slot structure 27, so that the end flange 19 and the rear flange 20 are inserted into the support bracket 14. Thus, the end flange 19, the end support bracket 14, the circuit board 17, the tail support bracket 14 and the tail flange 20 can be connected in series to be integrated, facilitating assembly into the first receiving cavity of the housing member 2.

As shown in fig. 8-11, the mounting holes 21 of the end flange 19 and the tail flange 20 have outward steps 22, and the steps 22 are used for clamping the feed-through 8 to the mounting holes 21, so that the feed-through 8 seals the housing shell 11. Further, a first locking structure 16 for locking with the housing shell 11 is provided on the side of the end flange 19 and the tail flange 20 facing the support bracket 14, and the first locking structure 16 is used to abut against the end of the housing shell 11, thereby blocking the relative axial movement of the housing shell 11. In addition, after the end flange 19, the tail flange 20, the support bracket 14 and the housing shell 11 are assembled, the housing shell 11 may wrap the end flange 19, the tail flange 20 and the rest of the support bracket 14 except the first clamping structure 16 of the end flange 19, so as to improve the sealing performance of the whole assembly. Through the above design, the sequential assembly or disassembly of the housing component 1 of the implantable neural stimulator from the end flange 15 to the tail flange 16 or from the tail flange 16 to the end flange 15 can be facilitated.

Fig. 12 shows another embodiment of the implantable neurostimulator, in which suture holes 5 are designed on the outer walls of the end part 1 and the tail part 25, so as to further enhance the connection with the human tissue.

It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications therefrom are intended to be within the scope of the invention.

Claims

1. An implantable neurostimulator adapted for a human extremity, comprising: an end part component (1), a shell component (2) and a tail part component (25) which are connected in sequence to form a column shape;

a circuit board (17) is arranged inside the shell component (2);

a wireless charging coil (6) is arranged in the end part component (1), and the central axis of the wireless charging coil (6) is parallel to the length direction of the shell component (2);

an electrode connector (4) for inserting an electrode (3) is arranged in the tail part (25), and the central axis of a connecting channel of the electrode connector (4) is parallel to the length direction of the shell part (2).

2. The implantable neural stimulator of claim 1, wherein the housing component (2) comprises: the shell comprises a shell (11), an end flange (19) and a tail flange (20), wherein the two ends of the shell (11) are respectively connected with the end flange (19) and the tail flange (20).

3. The implantable neural stimulator of claim 2, wherein the housing shell (11) comprises: a planar wall (12) and an arcuate wall (13), the circuit board (17) being disposed within the housing member (2) proximate the planar wall (12) of the housing shell (11), the circuit board (17) being disposed in spaced parallel relation to the planar wall (12) of the housing shell (11).

4. The implantable neural stimulator according to claim 3, wherein both ends of the housing shell (11) are provided with detachable support brackets (14), and the inner wall of the support brackets (14) is provided with support bosses (15) for supporting the circuit board (17).

5. The implantable neural stimulator according to claim 3, wherein the end flange (19) and the tail flange (20) are respectively provided with a mounting hole (21) for mounting the feed-through (8), and the wireless charging coil (6) and the antenna (7) are electrically connected with the circuit board (17) inside the shell component (2) through the feed-through (8) by connecting leads.

6. The implantable neural stimulator of claim 1, wherein the tip component (1) and the tail component (25) are made of a polymeric material.

7. The implantable neural stimulator according to claim 6, wherein the end part (1) and the tail part (25) are cast molded from epoxy.

8. The implantable neural stimulator according to claim 1, wherein one end of the electrode (3) is fixed by snap-fitting within a connection channel of the electrode connector (4).

9. The implantable neurostimulator according to claim 8, wherein the connection channel of the electrode connector (4) has an annular groove (9) therein, and the electrode (3) has an annular flange (10) thereon, said annular flange (10) being adapted to snap into said annular groove (9).

10. The implantable neural stimulator according to claim 1, wherein the end part (1) and/or the tail part (25) is/are designed with suture holes (5).