CN114271285A

CN114271285A - Weeding composition and preparation thereof

Info

Publication number: CN114271285A
Application number: CN202210008241.5A
Authority: CN
Inventors: 曹晓晓; 吴电亮; 张建邦; 黄自云; 陈金红; 马伦东; 吕晓曦
Original assignee: Dingyuan Zhongbang Bioengineering Co ltd
Current assignee: Dingyuan Zhongbang Bioengineering Co ltd
Priority date: 2022-01-05
Filing date: 2022-01-05
Publication date: 2022-04-05
Anticipated expiration: 2042-01-05
Also published as: CN114271285B

Abstract

The invention relates to a weeding composition, which comprises active ingredients of metamifop, oxaziclomefone and fluroxypyr-meptyl in a weight ratio of 20-30:4-8: 3-6. The herbicidal composition of the present invention may further comprise agriculturally acceptable adjuvants and carriers, and may be prepared in agriculturally acceptable dosage forms, preferably in the form of a cream formulation. The invention also relates to the application of the missible oil in preventing and controlling agricultural weeds.

Description

Weeding composition and preparation thereof

Technical Field

The invention relates to the field of agriculture, and in particular relates to a weeding composition containing metamifop, oxaziclomefone and fluroxypyr-meptyl, an emulsifiable concentrate preparation of the weeding composition, and application of the weeding composition in preventing and treating agricultural weeds.

Background

Metamifop is an aryloxy phenoxy propionate herbicide developed by Korean chemical technology research institute, the action mechanism of the herbicide is to inhibit acetyl coenzyme A carboxylase, and the herbicide mainly prevents and kills most annual gramineous weeds in transplanting and direct sowing fields, has low toxicity and is safe to the environment. The herbicide is mainly absorbed by plant stems and leaves, and effective components need to reach targets in plants to play a role in weed control, so that the requirement on an auxiliary agent system is relatively high, and the effective components enter the plants to play a role through the effects of a solvent, a surfactant and the like.

The oxaziclomefone is a herbicide which is created by Mitsubishi oilification corporation and developed together with the Japanese agricultural cooperation union, belongs to a systemic conduction type paddy field herbicide and is mainly absorbed by the roots, stems and leaves of weeds. The oxaziclomefone has high safety for transplanted rice, and is efficient and long in residual effect on annual weeds of the rice.

The chlorofluoropyridinates are aryl picolinate compounds developed by the Dow company, belong to auxin herbicides, and have the action mechanism of causing over-stimulation of specific auxin regulating genes and interfering the growth process of plants. The fluroxypyr-meptyl can be absorbed by leaves and roots of plants, has systemic conductivity, and can be used for crops such as paddy fields and the like to prevent and remove grassy weeds, broadleaf weeds and nutgrass flatsedge.

CN 108849924A discloses a composition containing oxaziclomefone and metamifop, which can be prepared into various formulations such as missible oil, suspending agent, aqueous emulsion, microemulsion, water dispersible granule or wettable powder. However, the innovation of this patent application is focused on the study of the synergistic effect of the two active ingredients, and although some formulation examples are given, the physicochemical properties of the formulation are not evaluated.

CN105613522A discloses a composition containing oxaziclomefone and metamifop, and describes that the composition can be prepared into various dosage forms. The same emphasis of the patent application is focused on the synergistic effect of the two active ingredients, and the screening research and various physicochemical property evaluations of the preparation are lacked.

CN106857561A discloses a composition of oxaziclomefone and metamifop, and describes that the composition can be prepared into various dosage forms. The same emphasis of the patent application is focused on the synergistic effect of the two active ingredients, and the screening research and various physicochemical property evaluations of the preparation are lacked.

CN109221137A discloses a weeding composition containing fluroxypyr ester and oxaziclomefone, which can be prepared into various preparations and used for preventing and killing the occurrence and the prevalence of paddy weeds in paddy fields.

CN113575593A contains a compound preparation of fluroxypyr-meptyl and metamifop, can be prepared into various formulations and can prevent and kill gramineae and broad-leaved weeds of paddy fields.

None of the above prior art discloses a ternary complex composition comprising metamifop, oxaziclomefone and fluroxypyr meptyl. In addition, although the above documents describe various formulations of binary compositions, there is no screening study on formulations of pesticide formulations having excellent performance in actual studies, and the performance indexes thereof are not evaluated.

The missible oil as a traditional pesticide preparation has the advantages and disadvantages of clear and clear formulation, simple processing technology, good stability and high biological activity, and the disadvantages of the missible oil mainly show poor environmental compatibility. Due to the advantages of the missible oil, the missible oil is still one of important pesticide formulations, even in countries such as America and Europe with developed environment-friendly preparations, the proportion of the missible oil preparation still exceeds one fourth, and the missible oil occupies the first place in pesticide preparations in China for a long time.

Therefore, the development of emulsifiable concentrate preparations with excellent performances in various aspects such as environmental compatibility, emulsifying dispersibility, stability and the like still has wide market prospect. At present, objective requirements for obtaining a preparation system with excellent performance indexes, improving the performance of the preparation to the maximum extent and improving the bioavailability still exist.

Disclosure of Invention

In order to solve the problems in the prior art, the inventor obtains a ternary compound synergistic composition containing metamifop, oxaziclomefone and chloropyridyl ester through a large number of biological tests. Meanwhile, a formulation formula screening test is carried out by combining the physicochemical properties of the three active ingredients, and a proper auxiliary agent compatibility is selected, so that missible oil with excellent quality indexes is obtained, and the invention is completed based on the facts.

The invention is completed by the following technical scheme.

The invention relates to a weeding composition, which comprises active ingredients of metamifop, oxaziclomefone and fluroxypyr-meptyl in a weight ratio of 20-30:4-8: 3-6.

In a preferred embodiment of the invention, the herbicide composition only contains three active ingredients of metamifop, oxaziclomefone and fluroxypyr-meptyl.

In a preferred embodiment of the invention, the weight ratio of metamifop, oxaziclomefone and fluroxypyr-meptyl is preferably 23-26:5-7.5:4-5, more preferably 25:6: 4.5.

The weeding composition can further comprise agriculturally acceptable auxiliaries and carriers, and is prepared into agriculturally allowable dosage forms.

Preferably, the composition comprising metamifop, oxaziclomefone and fluroxypyr ester is prepared into an emulsifiable concentrate preparation, and the emulsifiable concentrate preparation consists of the following components in percentage by weight:

metamifop 20-30%

Oxaziclomefone 4-8%

Chlorofluoropyridine ester, 3-6%

Cosolvent 6-12%

15 to 25 percent of emulsifier

Solvent, make up to 100%.

Preferably, the missible oil preparation comprises the following components in percentage by weight:

metamifop 23-26%

Oxaziclomefone 5-7.5%

Chlorofluoropyridine esters, 4-5%

Cosolvent 9-11%

18 to 22 percent of emulsifier

Solvent, make up to 100%.

More preferably, the missible oil preparation comprises the following components in percentage by weight:

metamifop, 25%

Oxaziclomefone, 6%

Chlorofluoropyridine ester, 4.5%

Cosolvent accounting for 10 percent

20 percent of emulsifier

Solvent, make up to 100%.

In the emulsifiable concentrate formulation of the present invention, wherein:

the emulsifier is a composite emulsifier containing calcium dodecyl benzene sulfonate, isooctanol polyoxyethylene polyoxypropylene ether and castor oil polyoxyethylene ether, wherein the weight ratio of the calcium dodecyl benzene sulfonate, the isooctanol polyoxyethylene polyoxypropylene ether and the castor oil polyoxyethylene ether is 1-2:2-4:1-2, and the most preferable ratio is 1:2: 1.

According to the invention, three composite emulsifiers are selected, compared with other emulsifiers and the emulsifiers used alone, the emulsifying property and emulsion stability of the missible oil preparation can be greatly improved, and the storage on the shelf and the drug effect exertion of the missible oil preparation are both very favorable.

The cosolvent is selected from one or more of cyclohexanone, isophorone, propanol and butanol; cyclohexanone is preferred.

The solvent is selected from one or more of No. 100 solvent oil, No. 150 solvent oil, n-hexane and n-heptane; preferably 150 # solvent oil.

Another aspect of the invention relates to a process for the preparation of the above emulsifiable concentrates, which process is well known to the person skilled in the art, for example by the specific steps: adding the cosolvent with the formula amount into the solvent with the formula amount, then adding the active ingredient with the formula amount, dissolving the active ingredient, then adding the emulsifier, and uniformly mixing.

Another aspect of the invention relates to the use of said herbicidal composition, in particular an emulsifiable concentrate formulation comprising metamifop, oxaziclomefone and fluroxypyr-meptyl, for controlling agricultural weeds. Preferably, the herbicidal composition, especially an emulsifiable concentrate formulation comprising metamifop, oxaziclomefone and fluroxypyr ester is used for controlling agricultural weeds in paddy fields, including barnyard grass, moleplant seed, monochoria vaginalis, cyperus heterophylla, ludwigia prostrata and the like.

In the application of the present invention, the herbicidal composition, especially the emulsifiable concentrate formulation comprising metamifop, oxaziclomefone and fluroxypyr ester, is applied by spray application after dilution at an application rate of 5 to 100g ai/mu, preferably 10 to 60g ai/mu.

The invention has the beneficial effects that:

compared with each single agent and the combination of each two, the weeding composition containing metamifop, oxaziclomefone and fluroxypyr meptyl has remarkable synergistic effect.

The emulsifiable concentrate formula obtained by screening the specific auxiliary agent has excellent physicochemical properties such as emulsibility, emulsion stability, storage stability and the like, which is beneficial to the shelf stability of the pesticide, the bioavailability of the pesticide after application, the drug effect exertion and the like.

In addition, through field bioassay, the emulsifiable concentrate preparation of the composition shows excellent control effect on weeds in paddy fields.

Detailed Description

The technical solutions and effects of the present invention will be further described with reference to specific examples, but the present invention is not limited to the scope of the examples. The percentages of the invention are weight percentages.

Calcium dodecylbenzenesulfonate used in the following examples of the present invention was purchased from clariant (trade name Phenylsulfonat CA); castor oil polyoxyethylene ether (EL36) available from clariant; isooctanol polyoxyethylene polyoxypropylene ether EH9 was purchased from dow (Ecosurf EH 9); other auxiliaries are also commercially available.

First, indoor bioassay

The herbicidal activity of the herbicidal composition of the present invention passes the fourth part of the herbicide of "indoor bioassay test criteria for pesticides NY/T1155.4-2006: activity measurement test the stem and leaf spray method was used.

Test targets: barnyard grass (Echinochlorusgalli (L.) Beauv);

reagent to be tested: metamifop, oxaziclomefone and fluroxypyr ester, and a two-by-two composition and a three-by-three composition thereof. When the medicine is prepared, the original medicine is firstly dissolved by using a proper amount of No. 150 solvent oil, and then 2% of Tween 80 aqueous solution is used for preparing the medicine with the required concentration.

The test method comprises the following steps: and (4) sowing barnyard grass in the nutrition pot. When the barnyard grass grows to 4-5 leaves, spraying treatment (the amount of sprayed liquid is 30L per mu) is carried out for each treatment, the treatment is repeated for 4 times, and the treatment without the medicament is used as a blank control. And after the liquid medicine on the surfaces of the weed leaves is naturally air-dried, transferring the weed leaves into a greenhouse for conventional culture. The fresh weight control effect of each treatment is investigated 21 days after the treatment:

e: fresh weight control effect;

c: control weed aerial fresh weight;

t: treating the fresh weight of the overground part of the weeds;

the combined effect of the compositions was then calculated according to the Colby formula (s.r. Colby, marketing synergy and antibiotic responsiveness of pharmaceutical compositions, seeds, 1967):

or

X is the control effect when active component a is applied at an application rate of m, expressed as a percentage of the untreated control group;

y is the control effect when active component B is applied at an application rate of n, expressed as a percentage of the untreated control group;

z is the control effect when active component C is applied at an application rate of r, expressed as a percentage of the untreated control group;

e is the control effect when active components a and B are applied at application rates of m and n, expressed as a percentage of the untreated control group (formula 1); or E is the control effect when active ingredient A, B, C is applied at an application rate of m, n, r, expressed as a percentage of the untreated control group (equation 2).

If the observed value of the control effect (actual control effect) is higher than the theoretical value calculated by the above formula, the composition has super-additivity, i.e. there is a synergistic effect.

The results of the measurements of barnyard grass by the herbicidal compositions of the present invention are shown in Table 1 below.

TABLE 1 indoor virulence determination results

The results in table 1 show that the combination of metamifop, oxaziclomefone and fluroxypyr-meptyl has a remarkable synergistic effect compared with each single agent and each two agents.

Second, screening of emulsifiers

Through solubility screening tests, the No. 150 solvent naphtha has better solubility on metamifop, oxaziclomefone and fluroxypyr meptyl, and the dissolving capacity is further improved when a cosolvent cyclohexanone is added, so that the No. 150 solvent naphtha is used as a solvent, and the cyclohexanone is used as the cosolvent for emulsifier screening.

1. Emulsifier screening of Single active ingredients

Calcium dodecylbenzene sulfonate, sodium dodecyl sulfate, polyethylene glycol stearate, castor oil polyoxyethylene ether (EL36), nonylphenol polyoxyethylene (60) ether, phenethyl phenol polyoxyethylene (60) ether, span-60, a methyl naphthalene sodium sulfonate formaldehyde condensate and isooctanol polyoxyethylene polyoxypropylene ether EH9 are selected as alternative emulsifier varieties and are respectively screened. The specific method comprises the following steps: respectively adopting the emulsifiers to independently prepare 10 percent of metamifop emulsifiable concentrate, 10 percent of oxaziclomefone emulsifiable concentrate and 10 percent of fluroxypyr meptyl emulsifiable concentrate (the content of each component in the formula is 10 percent of active ingredient, 5 percent of cyclohexanone, 10 percent of emulsifier, and the content of No. 150 solvent oil is up to 100 percent), and evaluating the emulsibility of the prepared emulsifiable concentrate.

The measuring method of the emulsibility comprises the following steps: filling 99.5mL of distilled water into a 100mL measuring cylinder, transferring 0.5mL of missible oil, then covering a plug, turning the measuring cylinder for 15 times, observing the colostrum state, and judging according to the following standards:

and (3) excellent: the emulsion is transparent or semitransparent and has stronger opalescence;

good: the emulsion is milky white or slightly bluish, the bottom is provided with opalescence, and the wall of the emulsion is provided with an emulsion membrane;

can be as follows: the emulsion is in an emulsified state and has no luster;

difference: the emulsion is off-white or has visible particles or flocs.

The results of the screening are shown in tables 2 to 4 below.

Results of screening metamifop emulsifiable concentrate emulsifier with concentration of 210% in table

Screening result of table 310% oxaziclomefone emulsifiable concentrate emulsifier

TABLE 410% screening results of emulsion emulsifier of fluroxypyridine ester

And (3) combining the screening results, selecting emulsifiers of calcium dodecyl benzene sulfonate, castor oil polyoxyethylene ether (EL36) and isooctanol polyoxyethylene polyoxypropylene ether EH9 which show 'good' or more for three active ingredients, and screening the composite emulsifier.

2. Screening of composite emulsifier

Emulsifiable concentrates were prepared according to the following table 5 using the above-mentioned emulsifiers preliminarily screened, respectively, and the emulsion stability of the prepared emulsifiable concentrates was evaluated. Wherein, the emulsion stability is determined by referring to GB/T1603-2001 which is a method for determining the stability of pesticide emulsion: 100mL of 30. + -. 2 ℃ standard hard water was added to a 250mL beaker, and 2mL of an emulsion sample was pipetted and added slowly to the hard water with stirring to prepare an emulsion. And after the emulsion is added, continuing stirring at the speed of 2-3r/s for 30s, immediately transferring the emulsion into a clean and dry measuring cylinder, placing the measuring cylinder in a constant-temperature water bath, standing for 1h at the temperature of 30 +/-2 ℃, taking out, and observing the separation condition of the emulsion, wherein if no precipitate (including oily matters and solids) exists in the measuring cylinder, the stability of the emulsion is judged to be qualified.

TABLE 5 composite emulsifier screening

The results of the complex emulsifier screening are shown in table 5. The results show that when the calcium dodecyl benzene sulfonate, the isooctanol polyoxyethylene polyoxypropylene ether EH9 and the castor oil polyoxyethylene ether (EL36) form the composite emulsifier, and the proportion is 1-2:2-4:1-2 (No. 5-9), the emulsifiable concentrate preparation with excellent performance can be prepared, wherein when the proportion of the calcium dodecyl benzene sulfonate, the isooctanol polyoxyethylene polyoxypropylene ether EH9 and the castor oil polyoxyethylene ether (EL36) is 1:2:1 (No. 7), the obtained emulsifiable concentrate has the best performance.

Second, preparation examples

Example 1

The formula comprises the following components: 25% of metamifop, 6% of oxaziclomefone, 4.5% of fluroxypyridine, 10% of cyclohexanone, 5% of calcium dodecyl benzene sulfonate, 5% of isooctanol polyoxyethylene polyoxypropylene ether EH 910%, 5% of castor oil polyoxyethylene ether (EL36) and the balance of No. 150 solvent oil to 100%.

The preparation method comprises the following steps: adding the cosolvent with the formula amount into the solvent with the formula amount, adding the active ingredient with the formula amount, dissolving the active ingredient, adding the emulsifier, and uniformly mixing to obtain the product.

Example 2

The formula comprises the following components: 24% of metamifop, 7% of oxaziclomefone, 5% of fluroxypyridine, 10% of cyclohexanone, 4% of calcium dodecyl benzene sulfonate, 8% of isooctanol polyoxyethylene polyoxypropylene ether EH 98%, 8% of castor oil polyoxyethylene ether (EL36) and the solvent oil No. 150, wherein the total amount is 100%.

The preparation method is the same as that of example 1.

Example 3

The formula comprises the following components: 26% of metamifop, 5% of oxaziclomefone, 5% of fluroxypyridine, 10% of cyclohexanone, 8% of calcium dodecyl benzene sulfonate, 8% of isooctanol polyoxyethylene polyoxypropylene ether EH 98%, 4% of castor oil polyoxyethylene ether (EL36) and the balance of No. 150 solvent oil to 100%.

The preparation method is the same as that of example 1.

Example 4

The formula comprises the following components: 23% of metamifop, 7.5% of oxaziclomefone, 5.5% of fluroxypyridine, 10% of cyclohexanone, 5.6% of calcium dodecyl benzene sulfonate, 2.8% of isooctanol polyoxyethylene polyoxypropylene ether EH 911.2, 2.8% of castor oil polyoxyethylene ether (EL36) and the balance of No. 150 solvent oil to 100%.

The preparation method is the same as that of example 1.

Comparative example 1

The formula comprises the following components: 25% of metamifop, 6% of oxaziclomefone, 4.5% of fluroxypyridine ester, 10% of cyclohexanone, 10% of polyethylene glycol stearate, 10% of castor oil polyoxyethylene ether (EL36) and the balance of No. 150 solvent oil to 100%.

The preparation method is the same as that of example 1.

Comparative example 2

The formula comprises the following components: 25% of metamifop, 6% of oxaziclomefone, 4.5% of fluroxypyridine ester, 10% of cyclohexanone, 10% of calcium dodecylbenzene sulfonate, 10% of phenethyl phenol polyoxyethylene (60) ether and the balance of No. 150 solvent oil to 100%.

The preparation method is the same as that of example 1.

Comparative example 3

The formula comprises the following components: 25% of metamifop, 6% of oxaziclomefone, 4.5% of fluroxypyridine, 10% of cyclohexanone, 10% of isooctanol polyoxyethylene polyoxypropylene ether EH 910%, 10% of polyethylene glycol stearate and the balance of No. 150 solvent oil to 100%.

The preparation method is the same as that of example 1.

Comparative example 4:

25% of metamifop, 6% of oxaziclomefone, 4.5% of fluroxypyridine ester, 10% of cyclohexanone, 4% of alkylphenol polyoxyethylene ether, 15% of phenethyl phenol polyoxyethylene (60) ether and the balance of xylene to 100%.

The preparation method is the same as that of example 1.

The results of the measurements of emulsifiability, emulsion stability, and cold and hot storage stability of the examples and comparative emulsifiable concentrate formulations prepared as described above are shown in table 6 below. Wherein, the emulsibility and the emulsion stability are measured by the method; reference is made to GB/T19137-2003 and GB/T19136-2003 for methods for determining cold and hot storage stability, respectively.

TABLE 6 determination of quality index of emulsifiable concentrate preparation

The above results show that the emulsifiable concentrates of examples 1-4 of the present invention have better quality indexes than those of the comparative examples 1-3. Among these, the formulation of example 1 is excellent in performance.

Third, biological test example

Test for determining pesticide effect of missible oil preparation of the invention on preventing water direct seeding of late rice field weeds

And (3) test crops: rice variety, middle group No. 3.

Control of a target: barnyard grass (Echinochlorusgalli (L.) Beauv).

Reagent to be tested: the test agents are the formulations of the present invention examples 1-4; control agents are comparative examples 1-4; clear water is a blank control.

The cultivation conditions are as follows: the test site is arranged in Wanshan Zhenggang of Lujiang county, Anhui province. The soil quality of the test field is paddy soil, the previous stubble is an early rice field, barnyard grass is main weed, the field surface is ploughed and harrowed smoothly, the irrigation is convenient, and the conditions of cultivation and water and fertilizer management in all test districts are uniform and consistent.

Setting a cell: randomly arranged, area 20m²(ii) a 3 times of repetition, in order to ensure independent irrigation and drainage, no mutual connection, drainage or leakage between areas, ridges are formed according to set communities, the height of the ridge is about 20cm, the width of the ridge is about 30cm, drainage ditches are reserved between the repetition intervals of 1m, and protection rows of 1m are arranged around the test area.

The application time is as follows: barnyard grass 4-5 leaf stage.

The application method comprises the following steps: spraying stem leaves, and spraying the solution with the amount of 30L per mu.

And (4) control effect investigation: at 34 days after drug administration, 3 spots are randomly selected from each cell, each spot is 0.25m²Respectively counting the number of plants of each target weed at each point, weighing the fresh weight of the overground part of each target weed at each point, repeatedly taking the average value for 3 times (the number of plants is rounded to obtain an integer), and respectively calculating the control effect.

And (3) calculating the drug effect: according to the pesticide field efficacy test criterion GB/T17980.40-2000, the prevention and control calculation method is calculated according to the formula:

in the formula: PT represents the residual grass number (or fresh weight) in the treatment area; CK represents the number of live grass (or fresh weight) in the blank control area.

The control effect is shown in table 7 below.

TABLE 7 test of the efficacy of controlling barnyard grass in paddy field

The above-described embodiments are merely exemplary embodiments adopted to illustrate the present invention, and the present invention is not limited thereto, and those skilled in the art can make various modifications and changes without departing from the spirit of the present invention, and these modifications and changes also fall within the scope of the present invention.

Claims

1. The weeding composition is characterized in that the active ingredients of the weeding composition comprise oxaziclomefone, metamifop and fluroxypyr-meptyl in a weight ratio of 20-30:4-8: 3-6.

2. The herbicidal composition as claimed in claim 1, wherein said herbicidal composition comprises only the three active ingredients, oxaziclomefone, metamifop and fluroxypyr meptyl.

3. A herbicidal composition according to claim 1 or 2, characterized in that the weight ratio of oxaziclomefone, metamifop and fluroxypyr ester is preferably 23-26:5-7.5: 4-5.

4. A herbicidal composition according to claim 3, characterized in that the weight ratio of oxaziclomefone, metamifop and fluroxypyr meptyl is preferably 25:6: 4.5.

5. A herbicidal composition according to any one of claims 1 to 4, characterized in that the herbicidal composition is in the form of an emulsifiable concentrate which consists of the following components in percentage by weight:

metamifop 20-30%

Oxaziclomefone 4-8%

Chlorofluoropyridine ester, 3-6%

Cosolvent 6-12%

15 to 25 percent of emulsifier

Solvent, make up to 100%;

wherein the emulsifier is a composite emulsifier containing calcium dodecyl benzene sulfonate, isooctanol polyoxyethylene polyoxypropylene ether and castor oil polyoxyethylene ether.

6. A herbicidal composition according to claim 5, characterized in that the weight ratio of calcium dodecylbenzenesulfonate, isooctanol polyoxyethylene polyoxypropylene ether and castor oil polyoxyethylene ether is 1-2:2-4: 1-2.

7. A herbicidal composition according to claim 5 or 6, characterized in that the weight percentages of the components are preferably:

metamifop 23-26%

Oxaziclomefone 5-7.5%

Chlorofluoropyridine esters, 4-5%

Cosolvent 9-11%

18 to 22 percent of emulsifier

Solvent, make up to 100%.

8. A herbicidal composition according to any of claims 5 to 7, characterized in that the co-solvent is selected from one or more of cyclohexanone, isophorone, propanol, butanol.

9. A herbicidal composition according to any one of claims 5 to 7, characterized in that the solvent is selected from one or more of the group consisting of mineral spirits No. 100, mineral spirits No. 150, n-hexane, n-heptane.

10. Use of the herbicidal composition of any one of claims 1 to 9 for controlling agricultural weeds.