CN114242264B

CN114242264B - Recommendation scheme display and generation method and device, computer equipment and storage medium

Info

Publication number: CN114242264B
Application number: CN202210171514.8A
Authority: CN
Inventors: 毛琇; 孙中雨; 杨威; 单少辉; 孙佳荣
Original assignee: Zhejiang Taimei Medical Technology Co Ltd
Current assignee: Zhejiang Taimei Medical Technology Co Ltd
Priority date: 2022-02-24
Filing date: 2022-02-24
Publication date: 2022-08-02
Anticipated expiration: 2042-02-24
Also published as: CN114242264A

Abstract

The embodiment of the specification provides a display method, a generation method, a device, computer equipment and a storage medium of a recommendation scheme of a clinical test item, and a requirement information display interface of the clinical test item is provided; and displaying the completed scheme of the clinical test item under the condition that a cost scheme recommendation control in the requirement information display interface is triggered, wherein the displayed cost scheme comprises the recommendation scheme, and the recommendation scheme is provided with recommendation identification information. In the embodiment of the specification, the displayed cost scheme takes the group entry time of the clinical test item subjects and the marketing requirement of the products after being listed into the market into consideration at the same time, and provides a more accurate cost scheme for the user.

Description

Recommendation scheme display and generation method and device, computer equipment and storage medium

Technical Field

The embodiment of the specification relates to the technical field of clinical tests, in particular to a display method, a generation device, computer equipment and a storage medium of a recommendation scheme of a clinical test project.

Background

With the development of medical technology, clinical trial items are gradually increasing. Typically, a clinical trial project may be performed by a clinical institutional administration organization SMO in a research center.

In conventional technology, clinical trial projects may be performed by different clinical institutional regulatory organizations SMO at different research centers. At the time of clinical trial project establishment, the clinical trial project sponsor may receive a cost plan comprising information related to the clinical institution administration organization SMO and the research center. The cost scheme has important influence on the cost and the execution process of the clinical test project.

However, the accuracy of the protocol of clinical trial projects in the conventional technology needs to be improved.

Disclosure of Invention

In view of this, embodiments of the present disclosure are directed to providing a method, an apparatus, a computer device, a storage medium, and a computer program product for displaying a recommendation scheme of a clinical test item, so as to solve the technical problem in the conventional art that the accuracy of the recommendation scheme of the clinical test item needs to be improved.

The embodiment of the specification provides a display method of a recommendation scheme of a clinical test item, which is applied to a client side and comprises the following steps: providing a requirement information display interface of the clinical test item; the requirement information display interface is provided with a cost scheme recommendation control and the project requirement information of the clinical test project; sending the project requirement information to a server under the condition that the cost scheme recommendation control is triggered; wherein the project requirement information is used for instructing the server to generate a plurality of cost schemes of the clinical test project; wherein the cost plan has marketing estimate data for a product involved in the clinical trial program and an estimated length of time to group for a subject required for the clinical trial program; determining a recommended plan in each of the achievement plans based on the marketing estimation data and the grouping estimation duration of each of the achievement plans; receiving the clinical test project completion scheme sent by the server; presenting at least part of the received cost plan; wherein the displayed cost scheme comprises the recommendation scheme, and the recommendation scheme is provided with recommendation identification information.

The embodiment of the specification provides a method for generating a recommendation scheme of a clinical test item, which is applied to a server and comprises the following steps: receiving project requirement information of the clinical test project; generating a number of cost plans for the clinical trial project based on the project requirement information; wherein the cost plan has marketing estimate data for a product involved in the clinical trial program and an estimated length of time to group for a subject required for the clinical trial program; determining a recommendation scheme in each of the achievement schemes according to the marketing estimation data and the grouping estimation duration of each of the achievement schemes; sending the completed scheme of the clinical trial project to a client so that the client displays at least part of the received cost scheme; and the recommendation scheme in the displayed cost scheme has recommendation identification information.

The embodiment of the present specification provides a display device for a recommendation scheme of a clinical trial item, which is applied to a client, and the device includes: the display interface providing module is used for providing a requirement information display interface of the clinical test project; the requirement information display interface is provided with a cost scheme recommendation control and the project requirement information of the clinical test project; the requirement information sending module is used for sending the project requirement information to a server under the condition that the cost scheme recommendation control is triggered; wherein the project requirement information is used for instructing the server to generate a plurality of cost schemes of the clinical test project; wherein the cost plan has marketing estimate data for a product involved in the clinical trial program and an estimated length of time to group for a subject required for the clinical trial program; determining a recommended plan in each of the achievement plans based on the marketing estimation data and the grouping estimation duration of each of the achievement plans; the cost scheme receiving module is used for receiving the clinical test project completion scheme sent by the server; the cost scheme display module is used for displaying at least part of the received cost scheme; wherein the displayed cost scheme comprises the recommendation scheme, and the recommendation scheme is provided with recommendation identification information.

The embodiment of the present specification provides an apparatus for generating a recommendation scheme for a clinical test item, which is applied to a server, and the apparatus includes: the requirement information receiving module is used for receiving the project requirement information of the clinical test project; a cost plan determination module for determining a cost plan for the clinical trial project based on the project requirement information; wherein the cost plan has marketing estimate data for a product involved in the clinical trial program and an estimated length of time to group for a subject required for the clinical trial program; a recommendation scheme determining module, configured to determine a recommendation scheme in each of the achievement schemes according to the marketing estimation data of each of the achievement schemes and the grouping estimation duration; the cost scheme returning module is used for sending the cost scheme of the clinical test project to a client so that the client can display at least part of the received cost scheme; wherein the displayed cost scheme comprises the recommendation scheme, and the recommendation scheme is provided with recommendation identification information.

The present specification provides a computing device, comprising a memory and a processor, wherein the memory stores a computer program, and the processor implements the method steps of the above embodiments when executing the computer program.

The present specification provides a computer readable storage medium, on which a computer program is stored, which when executed by a processor implements the method steps in the above embodiments.

The present specification provides a computer program product, which includes instructions that, when executed by a processor of a computer device, enable the computer device to execute the method steps in the above embodiments.

According to the embodiment of the specification, a requirement information display interface of the clinical test project is provided; and under the condition that a cost scheme recommendation control in the requirement information display interface is triggered, displaying the finished scheme of the clinical test item, the marketing estimation data based on the cost scheme and the grouping estimation duration to recommend the cost scheme, wherein the displayed cost scheme takes the grouping time of a subject of the clinical test item and the marketing requirement of the product after the product is listed into consideration, and provides a more accurate cost scheme for the user. The cost scheme informs the user of the cost required to be invested for the clinical test items, and provides reference basis for the user to make decisions. Furthermore, an accurate cost scheme is provided for a user before the project is executed, so that the error between the actual cost and the estimated cost consumed during the project execution is reduced, the execution of the clinical test project is facilitated, and the execution quality of the clinical test project is improved.

Drawings

The accompanying drawings, which are included to provide a further understanding of the embodiments of the specification and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the embodiments of the specification. In the drawings.

FIG. 1a is an interactive diagram illustrating a method for presenting a recommendation of a clinical trial item, according to an embodiment.

FIG. 1b is a diagram illustrating an application environment of a method for presenting a recommended clinical trial item according to an embodiment.

FIG. 1c is a flow chart illustrating a method for presenting a recommended clinical trial item according to an embodiment.

FIG. 2a is a flow chart illustrating a method for presenting a recommended clinical trial item according to an embodiment.

Fig. 2b is a schematic diagram illustrating a demand information display interface according to an embodiment.

Fig. 2c is a schematic diagram illustrating a cost scheme and recommended identification information according to an embodiment.

Fig. 3 is a schematic diagram of a demand information display interface according to an embodiment.

Fig. 4 is a schematic diagram of a demand information display interface according to an embodiment.

Fig. 5 is a schematic diagram of a demand information display interface according to an embodiment.

FIG. 6 is a diagram illustrating a cost scheme and recommended identification information, according to an embodiment.

FIG. 7 is a diagram illustrating a cost scheme and recommended identification information, according to an embodiment.

Fig. 8a is a schematic diagram illustrating a cost scheme and recommended identification information according to an embodiment.

FIG. 8b is a schematic diagram illustrating a portion of a cost scheme provided by an embodiment.

FIG. 8c is a diagram illustrating a portion of the content of a cost solution and a solution acquisition control, according to an embodiment.

Fig. 9 is a flowchart illustrating a method for generating a recommendation of a clinical trial item according to an embodiment.

Fig. 10 is a block diagram showing a display apparatus of a recommendation of a clinical trial item according to an embodiment.

Fig. 11 is a block diagram showing a configuration of a device for generating a recommendation of a clinical trial item according to an embodiment.

Fig. 12 is a diagram illustrating an internal structure of a computer device according to an embodiment.

Detailed Description

The technical solutions in the embodiments of the present disclosure will be clearly and completely described below with reference to the drawings in the embodiments of the present disclosure, and it is obvious that the described embodiments are only a part of the embodiments of the present disclosure, and not all of the embodiments. All other embodiments obtained by a person of ordinary skill in the art without any inventive work based on the embodiments in the present specification belong to the protection scope of the present specification.

In the following, some terms referred to in the present specification are explained, and the clinical trial of a drug refers to a systematic study of drugs in humans to determine the efficacy and safety of the drug. The clinical test stages of the medicine are divided into phase I, phase II, phase III clinical tests and phase IV clinical tests. Phase I is mainly related to preliminary clinical pharmacology and human safety evaluation tests. Phase II is understood to be the initial stage of treatment, which is primarily related to the initial assessment of the therapeutic effect and safety of the drug on the patient with the target indication, and also provides the basis for the design of phase III clinical trial studies and the determination of the dosage regimen for administration. Stage III can be understood as a treatment effect confirmation stage, which is mainly used for further verifying the treatment effect and safety of the drug on a target indication patient, evaluating the relationship between benefit and risk and finally providing a sufficient basis for the examination of a drug registration application. The stage IV is mainly a clinical trial after the drug is marketed, and after the drug is marketed, the therapeutic effect and adverse reaction of the drug under a wide range of use conditions are continuously followed to evaluate the interest and risk relationship in use in general or special populations and to improve the administration dosage and the like.

Generally speaking, in the process of clinical trials, clinical institution management organizations mainly assist researchers and research centers to complete non-medical judgment affairs in clinical trials, ensure quality and research progress of clinical trials, and promote standardization progress of clinical trials, and in addition, clinical institution management organizations also assist clinical trial applicants to recruit patients or healthy volunteers. In some scenarios, the clinical facility management organization is also referred to as a clinical trial site management organization.

Clinical institution management organizations often have Clinical Coordinator (CRC) teams and extensive Clinical trial organization coverage, can respond quickly to needs of sponsors, and are undoubtedly significant in accelerating and advancing Clinical trial processes. In some scenarios, a clinical laboratory is also referred to as a research center, such as a hospital or hospital department. Clinical facility regulatory organizations typically have CRC reserves in the provinces of the clinical testing facilities, and it should be applied that the number of clinical testing facilities that the clinical testing facilities are quickly configured to cover is required by the sponsor. The sponsor may be a pharmaceutical factory enterprise, and when a new drug is developed or a clinical test for a new drug is required, the sponsor submits a research order for a clinical test project to a third-party enterprise. The third-party enterprise receives a research order for the clinical trial project.

A clinical institutional administration organization may be understood as a business organization that exercises part of the investigator's job duties on behalf of the investigator, and the main business of a clinical institutional administration organization is to assist the investigator in performing specific transactional work in the nature of non-medical judgment in a clinical trial by dispatching a clinical Research coordinator, crc (clinical Research coordinator), to ensure that the clinical Research process complies with the specifications of the GCP and study protocol.

A third party enterprise may be understood as an intermediary organization connecting an applicant with a clinical institution management organization. And a clinical institution administration organization may be understood as connecting a third party enterprise with an intermediary institution in the study.

Please refer to fig. 1 a. In a specific scenario, before a pharmaceutical factory issues a drug, cost budget control and reporting are required in advance. The pharmaceutical factory enterprise can be used as an application of the clinical test project to provide project requirement information of the clinical test project to third-party enterprises. The third party enterprise receives project requirement information for the clinical trial project. The project requirement information may include at least one project parameter, and the project parameter may include at least one of an indication, a project stage, a target group entry number, an intention center, and the like.

In some embodiments, the terminal provides a requirement information presentation interface for the clinical trial project. The requirement information display interface comprises a cost scheme generation control and a requirement information input control. And receiving project parameters such as indications, project staging names, target group-entering instances, intention centers and the like input or designated by a user in response to the triggering operation of the demand information input control. After the input operation of the project parameters is completed, the user can trigger the cost scheme generation control, and in response to the trigger operation of the cost scheme generation control, the terminal sends project requirement information of the clinical test project to the server. The server receives project requirement information of the clinical trial project. The server generates a project completion scheme of the clinical test project based on project requirement information of the clinical test project. And the server returns the recommendation identification information of the cost scheme and the achievement scheme of the clinical test item to the terminal.

In some embodiments, a research center capable of undertaking clinical trial programs is determined based on the indication data, the project staging name, and the number of target cohort instances, the center of intent. Specifically, the server may store historical correspondence data between the name of the research center, the indication, and the project period in advance. And inquiring historical corresponding relation data based on the indication data and the project staging names to obtain a plurality of corresponding research center names. The names of the plurality of research centers correspond to historical disease source data of the research centers. The server may also store relationship data between the names of the research centers and the historical disease source data in advance, perform a query on the relationship data according to the corresponding research center names, and determine the number of subjects that can be recruited by each research center according to the query result. Based on the number of target grouping cases and the number of subjects capable of being recruited by each research center, research centers capable of bearing clinical trial projects are determined from the preliminary research centers corresponding to the names of the plurality of research centers.

Further, the number of study centers may be counted to obtain an estimated total number of study centers. It is to be appreciated that a portion of the research center may be a sponsor-specified intent center. Furthermore, the number of grouping examples that the intention center can be recruited can be determined according to the identification information of the intention center specified by the sponsor and the historical disease source data of the intention center. And acquiring the difference between the target grouping number of cases and the grouping number of cases, and determining part of research centers based on the indication data, the project stage name and the difference between the target grouping number of cases and the grouping number of cases. It is noted that the historical etiology data may be a historical length of time that could be recruited to subjects deposited by any research center. Historical etiology data may be the historical number of subjects enrolled for any study center deposited. Illustratively, the number of subjects that can be recruited by the research center may be estimated based on the historical number of subjects that can be recruited.

In some implementations, the server has an association data set. The incidence relation data set comprises at least one incidence relation data. The clinical institution management organization corresponding to the incidence relation data has qualification for executing the clinical test items in the research center corresponding to the incidence relation data. Specifically, a clinical institution management organization corresponding to the research center (i.e., a clinical institution management organization qualified to execute the clinical trial project at the research center) is determined by matching in the association data set based on the identification information of the research center capable of bearing the clinical trial project. The number of clinical institution management organizations can be counted to obtain an estimated total number of clinical institution management organizations.

In some embodiments, the cost estimate data for the clinical trial project is obtained based on a summary of the quote data for each clinical institution administration organization at the corresponding research center.

In some embodiments, the calculations may be based on historical data of clinical institutional regulatory organizations performing similar clinical trials and/or historical data of research centers performing similar clinical trials, resulting in an estimated time to group for all subjects required for a clinical trial and/or a study start time for a clinical trial. Specifically, in some embodiments, the server stores in advance historical data of clinical laboratory projects executed by clinical institution management organizations, such as historical time duration of recruitment of clinical institution management organizations to one subject, estimates the time duration of complete recruitment of subjects of the clinical institution management organizations based on the historical time duration and the number of subjects to be recruited by the clinical institution management organizations, and summarizes the time duration of need recruitment of each clinical institution management organization to obtain the estimated time duration of grouping of all subjects required by the clinical laboratory projects. In some embodiments, the server stores history data of similar clinical trial projects executed by the research center in advance, such as the historical time length of the clinical institution management organization recruiting to one subject to be enrolled in a group in any research center, estimates the time length of completing the recruiting of the subjects in the research center based on the historical time length and the number of the subjects that the clinical institution management organization needs to recruit to the research center, and sums the time lengths of the research centers to obtain the estimated time length of the complete subjects required by the clinical trial projects to be enrolled in the group.

Further, the cost estimation data of the clinical trial project, the estimated total amount of the clinical institution management organization, the estimated total amount of the research center, the grouping estimation duration and the research start time of the clinical trial project can be used for determining the achievement scheme of the clinical trial project.

In some embodiments, the number of protocol-generated clinical trial items may be greater than 1. The grouping estimation duration and/or the research start time of the clinical test project have an important influence on the execution period of the clinical test project, so that the time for the product related to the clinical test project to be listed is influenced, and the profit of a sponsor is further influenced. Accordingly, one or more recommended cost plans (i.e., recommendations) may be determined among the plurality of cost plans based on the grouping estimated time period and/or the study start time of the clinical trial project. It will be appreciated that some recommended solutions may have higher cost estimate data than at least some of the other recommended solutions, but time to market is a more significant indicator for the sponsor.

In some embodiments, after determining the research centers for the clinical trial projects based on the indication data, the project staging names, and the target grouping instances, the server may obtain at least one of the etiology data of the research centers and the sales data of the similar products. Marketing estimate data is determined based on the etiology data of the research centers and/or sales data of like products. The marketing estimation data includes at least one of the number of research centers that can become marketing points, proportion data that can become marketing points, and the number of research centers that reach a sales share preset condition. Specifically, based on the disease source data of these research centers and/or the sales data of the similar products, the research centers that can become marketing points are determined at these research centers. And counting and determining the number of research centers capable of becoming marketing distribution points to obtain the number of the research centers capable of becoming marketing distribution points. Based on sales data of similar products, research centers that can be set to meet preset conditions for sales shares are determined. And counting and determining the number of the research centers reaching the preset condition of the sales share to obtain the number of the research centers reaching the preset condition of the sales share. The sales share preset condition may be understood as the share of the market being higher than a preset threshold (e.g., 30%). The marketing problem of the product on the market is considered while the scheme is made, the marketing cost of an application party is reduced, and the commercial value of the cost scheme is ensured.

Finally, in some embodiments, the server may generate the recommendation identification information for the cost plan based on the marketing estimate data and the grouping estimate duration. And the server recommends identification information to the terminal clinical test project completion scheme and the cost scheme. And the terminal displays the success scheme of the clinical test item and the recommendation identification information of the cost scheme. In some embodiments, the terminal presents a plurality of cost plans for the clinical trial item, wherein each cost plan may have recommendation identification information, respectively, which may be in the form of symbols (such as a five-pointed star or a star sign) and/or text (such as "optimal", "medium", "worst" for marketing evaluation data or "shortest", "medium", "longest" for group-entry evaluation duration). In some embodiments, the terminal presents multiple cost solutions for the clinical trial items, wherein the solution with the highest recommendation index has recommendation identifying information, which may be in the form of symbols (such as a five-pointed star or an asterisk) and/or text (such as "optimal" for marketing evaluation data or "shortest" for grouping evaluation duration).

In some embodiments, the server may determine the recommendation among the cost solutions based on the marketing estimate data and the grouping estimate duration. And the server sends the completed scheme of the clinical test project to the terminal. And the terminal receives the sent cost scheme and displays at least part of the clinical test items which are the scheme and the recommendation identification information of the recommendation scheme. In some embodiments, the terminal presents a plurality of cost solutions for the clinical trial items, with the highest cost solution being recommended as the recommended solution. Where the cost plan with the highest recommendation index may have recommendation identification information, the recommendation identification information may be in the form of symbols (such as a five-pointed star or star sign) and/or text (such as a highlighted "recommendation").

Illustratively, the sponsor will issue a claim to clinical trial project A. The indication may be hypertension. The project staging may be XXX project III. The target cohort number can be understood as the number of subjects who ultimately participate in the clinical trial program, such as 23. The intent center may wish to have a research center, such as Shanghai's Y Hospital department, capable of performing the project.

Historical corresponding relation data among the research centers, indications and project stages are stored in advance, and the historical corresponding relation data is searched according to hypertension and XXX project stage III to obtain a plurality of research centers capable of executing clinical test projects A. The study centers that can execute the clinical trial A are determined in a plurality of study centers and Shanghai Hospital Y medicine, and the quantity statistics are carried out to obtain the estimated total quantity of the study centers (such as 30 cases for the first scheme and 26 cases for the second scheme).

And inquiring the incidence relation data between the research centers and the clinical institution management organization according to the obtained plurality of research centers and the internal medicine of the Shanghai Y hospital to obtain the clinical institution management organization capable of covering the research centers. The clinical institution management organization capable of executing the clinical trial item a is determined among the clinical institution management organizations capable of covering the research centers, and the number statistics is performed to obtain the estimated total number of the clinical institution management organizations (for example, 15 plans one and 13 plans two).

And historical quotation data of the same type of items similar to the clinical test item A of each clinical institution management organization are obtained, the historical quotation data of each clinical institution management organization are counted, and the counting result can be directly used as cost estimation data. Or adjusting the statistical result according to the actual situation, and using the adjusted statistical result as the cost estimation data (for example, a solution one is 2 ten thousand yuan, and a solution one is 1.5 ten thousand yuan).

The estimation may be based on historical data of similar clinical trial projects performed by clinical institution management organizations, and the estimated time to group for all subjects required for the clinical trial projects (e.g., 20 months for scenario one and 28 months for scenario two) may be obtained.

Therefore, the first scheme is obtained as follows: 15 clinical institutions managing organizations, 30 research centers, an estimated cost of 2 ten thousand yuan and an estimated time to group of 20 months. The obtained scheme two is as follows: 13 clinical institutions, 26 research centers, an estimated cost of 1.5 ten thousand yuan, and an estimated time to group of 28 months.

The terminal shows a scheme I and a scheme II, and can compare the scheme I with the scheme II, and although the estimated cost of the scheme I is higher than that of the scheme II, the grouping estimated time length of the scheme I is 8 months shorter than that of the scheme II. For the sponsor, the earlier the clinical trial project is completed, the earlier the drug is on the market, and thus the one recommended for the drug may be determined.

The embodiment of the specification provides a display system of a recommendation scheme of a clinical test item, and the display method of the recommendation scheme provided by the embodiment of the specification is applied to the recommendation system of the clinical test item scheme. The clinical trial project plan recommendation system may include a hardware environment formed by the terminal 110 and the server 120 of fig. 1 b. The terminal 110 communicates with the server 120 through a network. In some embodiments, the presentation method of the recommendation of the clinical trial item may be performed by the client. The client can run on the terminal electronic device. In particular, the client may run in terminal 110 in fig. 1b, for example. The terminal 110 provides a requirement information display interface of the clinical trial project; the requirement information display interface is provided with a cost scheme recommendation control and project requirement information of clinical test projects; the project requirement information is used for determining the finished scheme of the clinical test project; wherein the cost plan has marketing estimation data of products involved in the clinical trial project and estimated time duration of group entry of the subjects required for the clinical trial project; under the condition that the cost scheme recommendation control is triggered, displaying the cost scheme recommendation identification information and the cost scheme success scheme of the clinical test project; wherein the recommendation identification information is determined based on the marketing evaluation data and the grouping evaluation duration.

The terminal 110 may be, but is not limited to, various personal computers, notebook computers, smart phones, tablet computers, and portable wearable devices. The server 120 may be implemented as a stand-alone server or a server cluster composed of a plurality of servers. With the development of scientific technology, new computing devices, such as quantum computing servers, may be developed, and may also be applied to the embodiments of the present specification.

Referring to fig. 1c, the present specification provides a method for displaying a recommendation scheme of a clinical trial project, which is applied to a client, and the method for displaying the recommendation scheme of the clinical trial project may include the following steps.

And S110, providing a requirement information display interface of the clinical test item.

The requirement information display interface is provided with a cost scheme recommendation control and the item requirement information of the clinical test items. Specifically, the client provides a requirement information display interface of the clinical test project. And responding to the input operation of the project demand information through the demand information display interface, and displaying the project demand information in the demand information display interface. In some embodiments, the client may be provided with a project requirement uploading control, and the client may display the project requirement information in the requirement information display interface in response to a triggering operation of the project requirement uploading control, and may also upload the project requirement information of the clinical test project to the server, so that the server determines the completed solution of the clinical test project according to the project requirement information of the clinical test project.

And S120, sending the project requirement information to a server under the condition that the cost scheme recommendation control is triggered.

Wherein the project requirement information is used for instructing the server to generate a plurality of cost schemes of the clinical test project; wherein the cost plan has marketing estimate data for a product involved in the clinical trial program and an estimated length of time to group for a subject required for the clinical trial program; determining a recommended plan among the respective achievement plans based on the marketing estimation data and the grouping estimation duration of the respective achievement plans.

Specifically, the client monitors the cost scheme recommendation control, and when the cost scheme recommendation control is triggered, the client can send a cost scheme recommendation request to the server, where the cost scheme recommendation request carries the item requirement information of the clinical test item. The server may determine a number of research centers suitable for developing the clinical trial project based on the project requirement information for the clinical trial project. In some embodiments, the disease source data of a plurality of research centers can be obtained, and marketing estimation data of products related to the clinical test items can be estimated by combining the disease source data. The server may also determine an estimated time to group for the subject required for the clinical trial project based on project requirement information for the clinical trial project. Marketing estimate data and grouping estimate duration determined by the server based on project demand information of the clinical trial project can be at least part of the content of the cost plan. And comparing marketing estimation data and grouping estimation duration among the cost schemes, and determining a recommended scheme in each cost scheme according to a comparison result.

And S130, receiving the clinical test project achievement scheme sent by the server.

And S140, displaying at least part of the received cost scheme.

Wherein the displayed cost scheme comprises the recommendation scheme, and the recommendation scheme is provided with recommendation identification information.

Specifically, the server sends the protocol of the clinical trial project to the client. The clinical test project completion scheme sent by the server may be part or all of the clinical test project completion scheme generated by the server based on the project requirement information. And the client receives the transmitted completed scheme of the clinical test project and displays at least part of the received cost scheme. Illustratively, referring to FIG. 2c, the terminal presents three cost plans for the clinical trial item, the three cost plans including a recommendation, the recommendation having recommendation identification information.

The display method of the recommendation scheme of the clinical test item comprises the steps of providing a requirement information display interface of the clinical test item; and under the condition that a cost scheme recommendation control in the requirement information display interface is triggered, sending project requirement information to the server to enable the server to generate a plurality of cost schemes, determining a recommendation scheme in the cost schemes, and returning the cost scheme of the clinical test project to the client to enable the client to display the cost scheme. The user is informed of the cost required to be invested for the clinical test items through the recommendation scheme, and reference basis is provided for the user to make decisions. Furthermore, an accurate cost scheme is provided for a user before the project is executed, so that the error between the actual cost and the estimated cost consumed during the project execution is reduced, the execution of the clinical test project is facilitated, and the execution quality of the clinical test project is improved.

Referring to fig. 2a, the present specification provides a method for displaying a recommended protocol of a clinical trial project protocol. The presentation method of the recommendation of the clinical trial item may include the following steps.

And S210, providing a requirement information display interface of the clinical test item.

The requirement information display interface is provided with a cost scheme recommendation control and project requirement information of clinical test projects. In some embodiments, the requirement information presentation interface may be a user operation interface provided by the terminal for interacting with the user. The requirement information display interface can be provided with an input text box, the item requirement information input or designated by a user is received through the input text box, and the item requirement information can be displayed in the requirement information display interface. In some embodiments, the requirements information presentation interface may also have a cost plan recommendation control. The cost plan recommendation control may be triggered by a user to send a cost plan recommendation request to a server. The cost plan recommendation request carries the project requirement information.

Wherein, the project requirement information is used for determining the adult scheme of the clinical test project. Wherein the cost plan has marketing estimate data for the product involved in the clinical trial program and estimated length of time to group for the subject required for the clinical trial program. In some embodiments, the project requirement information may include at least one of an indication (such as may be hypertension), a project stage (such as XXX project stage III), a target enrollment count (which may be understood as the number of subjects who ultimately participate in a clinical trial project, such as 23), an intent center (a research center in which the sponsor wishes to be able to perform a project, such as shanghai hospital department), and the like. In some embodiments, the cost plan may be a decision plan or a cost analysis plan for a clinical trial project provided to the sponsor. The cost plan may include a quote for the clinical trial project, may include a list of research centers needed for the clinical trial project, may include a clinical institution management organization appropriate for the clinical trial project, may include a plan for subject enrollment, and may include marketing estimate data for products involved in the clinical trial project and an estimated length of time for subject enrollment required for the clinical trial project.

Specifically, the terminal provides a requirement information display interface of the clinical test project. And responding to the input operation of the project requirement information through the requirement information display interface, and displaying the project requirement information in the requirement information display interface. In some embodiments, the terminal may be provided with a project requirement uploading control, and the terminal may respond to a triggering operation of the project requirement uploading control, may display project requirement information in the requirement information display interface, and may also upload project requirement information of the clinical test project to the server, so that the server determines the completed scheme of the clinical test project according to the project requirement information of the clinical test project.

In some embodiments, referring to fig. 2b, a demand information display interface includes a demand information input control. And responding to the triggering operation of the requirement information input control, receiving the project requirement information such as indication, project staging name, target group entering number and the like input or designated by a user, and displaying the project requirement information in a requirement information display interface.

And S220, displaying the cost scheme recommendation identification information of the cost scheme and the cost scheme of the clinical test item under the condition that the cost scheme recommendation control is triggered.

Wherein the recommendation identification information is determined based on the marketing evaluation data and the grouping evaluation duration. The marketing estimation data may be data derived from the product marketing situation and the marketing situation related to the clinical trial items. The marketing estimate data may be situation data representing a marketing point of a product to which the clinical trial item relates. The products involved in the clinical trial project may have the same type of products already on the market. The marketing estimation data may be derived based on sales data of similar products and project demand information. The sales data of the same kind of product may be point-of-sale distribution data of the same kind of product, such as an XX hospital or an XX pharmacy. The length of time to group estimate may be the length of time from the first subject to group to the clinical trial project. The grouping estimation time period may also be a time period from the grouping of all the subjects to the clinical trial item.

Specifically, the terminal monitors the cost scheme recommendation control, and when the cost scheme recommendation control is triggered, the terminal can send a cost scheme recommendation request to the server, where the cost scheme recommendation request carries the item requirement information of the clinical test item. The server may determine a number of research centers suitable for developing the clinical trial project based on the project requirement information for the clinical trial project. In some embodiments, the disease source data of a plurality of research centers can be obtained, and marketing estimation data of products related to the clinical test items can be estimated by combining the disease source data. The server may also determine an estimated time to group for the subject required for the clinical trial project based on project requirement information for the clinical trial project. Marketing estimation data and grouping estimation duration determined by the server based on the project requirement information of the clinical trial projects can be used as at least part of the content of the cost plan.

In some embodiments, the server may generate the recommendation identification information for the cost plan based on the marketing evaluation data and the grouping estimated duration. And the server returns the recommendation identification information of the cost scheme and the achievement scheme of the clinical test item to the terminal. And the terminal displays the success scheme of the clinical test item and the recommendation identification information of the cost scheme. The recommendation identification information may be information identifying whether the cost solution is recommended. The recommendation identification information may take the form of symbols (such as a five-pointed star or star sign) and/or text (the "best" of the marketing estimate data, or the "slowest", "fastest" of the grouping estimate duration, or the "earliest", "latest" of the start time).

In some embodiments, in order to facilitate a user to know the recommendation index of the cost solution in time, recommendation identification information may be set for the cost solution. For example, the recommendation identification information may be a fine-color symbol identifier, the recommendation index may be positively correlated to the number of fine-color symbols, and the higher the recommendation index is, the more the number of fine-color symbols is. The server may generate recommendation identification information based on the marketing evaluation data, taking into account marketing costs after the product is allowed to market. The recommendation identification information can be displayed at the corresponding position of the marketing estimation data, and the recommendation identification information can identify the marketing estimation data in text forms of 'highest', 'lowest' and the like, so as to inform the sponsor that the corresponding cost scheme is favorable for later marketing. In order to develop the clinical trial project as early as possible so that the product can be marketed as soon as possible and the time to market of the product is influenced by the time to be enrolled of the subject, the server may generate the recommended identification information based on the estimated time to be enrolled. The recommended identification information can be displayed at a corresponding position of the grouping estimated time length, and the recommended identification information can be used for identifying the grouping estimated time length in text forms of fastest text, slowest text, longest text, shortest text and the like and is used for reminding the sponsor whether the grouping time length of the corresponding cost scheme meets the requirement of the sponsor.

In some embodiments, the recommendation index for the cost plan may also be determined in conjunction with the marketing estimate data and the grouping estimate duration. Illustratively, the marketing estimation data and the grouping estimation time length are normalized, and the recommendation index of the cost scheme is obtained by summing calculation based on the marketing estimation data and the grouping estimation time length after the normalization processing. Specifically, the marketing estimation data and the grouping estimation duration weight ratio can be respectively set in combination with project experience, and the recommendation index of the cost plan is determined according to the respective weight ratio, marketing estimation data and grouping estimation duration. And generating recommendation identification information of the cost mode based on the recommendation index. And the marketing estimation data and the grouping estimation time weight ratio can be respectively set according to the demand degree of the sponsor on the marketing estimation data and the grouping estimation time. For example, if the sponsor compares the marketing costs of the products of interest, the weight proportion of the marketing estimate data may be set to be greater than the weight proportion of the time period of the grouping estimate. If the sponsor compares the product listing time of interest, the weight ratio of the marketing estimate data can be set to be less than the weight ratio of the grouping estimate duration.

The display method of the recommendation scheme of the clinical test item comprises the steps of providing a requirement information display interface of the clinical test item; and under the condition that a cost scheme recommendation control in the requirement information display interface is triggered, displaying the cost scheme of the clinical test item and recommendation identification information determined based on marketing estimation data and grouping estimation duration of the cost scheme, wherein the displayed cost scheme takes into account the grouping time of a subject of the clinical test item and the marketing requirement after the product is listed at the same time, and provides a more accurate cost scheme for the user. The cost scheme informs the user of the cost required to be invested for the clinical test items, and provides reference basis for the user to make decisions. Furthermore, an accurate cost scheme is provided for a user before the project is executed, so that the error between the actual cost and the estimated cost consumed during the project execution is reduced, the execution of the clinical test project is facilitated, and the execution quality of the clinical test project is improved.

In some embodiments, referring to fig. 3, the item requirement information includes indication data and number of subjects. The study center that undertakes the clinical trial project is determined based on the indication data and the number of subjects. Wherein the research center has incidence relation data. Wherein the clinical institution administrative organization having qualifications for performing the clinical trial project at the study center is determined based on the incidence relation data. Wherein the cost plan includes an estimated total for the research center and an estimated total for the clinical institution management organization.

Specifically, in some embodiments, the project requirement information includes indication data. The server stores the relation data of the indications and the research center in advance, and the relation data of the indications and the research center is stored in a database table form or in a database table. And the server matches the indication data in the relation data of the indication and the research center, and determines the identification information of the research center corresponding to the indication data. And acquiring the disease source data of the research center based on the identification information of the research center corresponding to the indication data. The number of subjects that the study center can recruit to was estimated in conjunction with the etiology data of any study center. The study centers capable of supporting clinical trial programs are determined from the study centers corresponding to the indication data on the basis of the number of subjects included in the project requirement information and the number of subjects recruitable by each study center. Further, the number of study centers that can undertake the clinical trial project can be counted to obtain an estimated total number of study centers. The cost plan includes an estimated total amount for the research center.

In some embodiments, because the subjects need to complete the screening according to certain criteria before they can be grouped, the screening process of the subjects will filter out some subjects that do not meet the requirements, and therefore, there is a certain screening rate for the subjects. Thus, the number of preliminary subjects to be recruited by each research center may be determined based on the number of subjects included in the project demand information and the screening efficiency. It is understood that the sum of the number of preliminary subjects is greater than the number of subjects included in the project requirement information.

In some embodiments, the server stores an association data set. The incidence relation data set comprises at least one incidence relation data. The associative relational data may be stored in the form of database tables or in database tables. In some embodiments, the research center and clinical institution management organization may correspond to a column of data in a database table. The clinical institution management organization corresponding to the incidence relation data has qualification for executing the clinical test items in the research center corresponding to the incidence relation data. Specifically, not any clinical institution management organization may implement clinical trial projects in the study centers in the study center list, and the server needs to match in the association relationship data set according to the study center capable of bearing the clinical trial projects. For example, the identification information of the research center is matched with the research center corresponding to any association relation data in the association relation data set, and the research center matched with the identification information of the research center is determined. Further, the clinical institution management organization to which the association data corresponds is determined as the clinical institution management organization qualified to execute the clinical trial project at the research center. Therefore, the number of the research centers capable of bearing the clinical test items can be counted to obtain the estimated total amount of the research centers. The cost plan includes an estimated total amount of clinical institution management organization

In some embodiments, the association relationship data includes relationship data of a research center name and a clinical institution management organization name. And comparing the name of the research center with the name of the research center corresponding to any incidence relation data in the incidence relation data set, and determining the research center with the same name as the research center.

In this embodiment, the study center that undertakes the clinical trial project is determined based on the indication data and the number of the subjects, and the clinical institution management organization that qualifies to execute the clinical trial project in the corresponding study center is determined based on the association data, so that the study center and the clinical institution management organization can be quickly and accurately determined, and the clinical institution management organization can be ensured to recruit a sufficient number of subjects for the clinical trial project in the study center, thereby ensuring the smooth implementation of the clinical trial project.

In some embodiments, referring to FIG. 4, the resource requirement information further includes a project name. The study center that undertakes the clinical trial program is determined based on the indication data, the name of the program, and the number of subjects.

The project name may be a name of a clinical test project or a project stage name of the clinical test project. Specifically, the project requirement information includes indication data and a project name. The server stores the relation data of the project name, the indication and the research center in advance, and the relation data of the project name, the indication and the research center are stored in a database table or stored in the database table. And the server matches in the relational data according to the project name and the indication data to determine the identification information of the corresponding research center. And acquiring the disease source data of the research center based on the identification information of the corresponding research center. The number of subjects that the study center can recruit to was estimated in conjunction with the etiology data of any study center. According to the number of subjects included in the project requirement information and the number of subjects that can be recruited by each research center, the research center that can undertake the clinical trial projects is determined among the corresponding research centers. In some embodiments, similarity search can be performed in the relation data of the project name, the indication and the research center by using the indication data and the project name included in the project requirement information to obtain the corresponding research center.

In some embodiments, the server stores data on the relationship between the project indication and the research center in advance. The item indications related to the relational data are generated by fusing the item names and the indication data. The adaptive data and the project name included in the project requirement information can be fused, the result of the fusion processing is used for matching with the project adaptive in the relation data, and the matched research center is used as the research center capable of bearing the clinical test project.

In the present embodiment, a study center capable of bearing clinical trial items is determined based on the indication data, the item name, and the number of subjects, and it is ensured that an appropriate study center can be found to develop clinical trial items.

In some embodiments, referring to FIG. 5, the project requirement information includes a sponsor designated research center capable of undertaking clinical trial projects. Wherein the research center has incidence relation data. Wherein the incidence relation data comprises relation data of a research center and a clinical institution management organization; a clinical institution management organization at the research center eligible to perform the clinical trial project is determined based on the incidence relation data; wherein the cost plan includes an estimated total amount of the clinical institution management organization.

In this case, the applicant may designate some or all of the research centers capable of bearing the clinical trial items in advance, and in this case, the research center designated by the applicant is prioritized. In some embodiments, by analyzing historical source data and/or similar project performance data of the sponsor-specified study center, etc., it is known that the sponsor-specified study center is not able to recruit a sufficient number of subjects, and in this case, a portion of the other study centers may be determined based on the indication data, the project name, and the number of subjects, or a portion of the other study centers may be determined based on the indication data and the number of subjects. The research center designated by the sponsor and the other research centers of the segment share clinical trial programs.

In some embodiments, through analysis of historical disease source data and/or similar project performance data of the research center designated by the sponsor, and the like, it is known that the research center designated by the sponsor can recruit a sufficient number of subjects, and at this time, the research center designated by the sponsor undertakes clinical trial projects, and the server is no longer required to match the appropriate research center according to project requirement information.

In some embodiments, the server stores an association data set. The incidence relation data set comprises at least one incidence relation data. The associative relational data may be stored in the form of database tables or in database tables. In some embodiments, the research center and clinical institution management organization may correspond to columns of data in database tables. The clinical institution management organization corresponding to the incidence relation data has qualification for executing the clinical test items in the research center corresponding to the incidence relation data. Specifically, not any clinical institution management organization may implement clinical trial projects in the study centers in the study center list, and the server needs to match in the association relationship data set according to the study center capable of bearing the clinical trial projects. For example, the identification information of the research center is matched with the research center corresponding to any association relation data in the association relation data set, and the research center matched with the identification information of the research center is determined. Further, the clinical institution management organization to which the association data corresponds is determined as the clinical institution management organization qualified to execute the clinical trial project at the research center. Therefore, the number of the research centers capable of bearing the clinical test items can be counted to obtain the estimated total amount of the research centers. The cost plan includes an estimated total amount of clinical institution management organizations.

In this embodiment, the clinical institution management organization qualified to execute the clinical trial projects in the research center designated by the sponsor is determined based on the association relationship data, so that the clinical institution management organization is quickly and accurately determined, a sufficient number of subjects can be recruited for the clinical trial projects in the research center, and the clinical trial projects are smoothly implemented.

In some embodiments, referring to FIG. 6, the cost plan further includes cost estimation data. The cost estimation data is obtained by summarizing price quotation data of each clinical institution management organization in a corresponding research center.

The cost estimation data may be cost data obtained by estimating the cost of the clinical trial project required to complete execution. The quotation data can be historical quotation data of a corresponding research center of a clinical institution management organization, or prediction quotation data obtained by prediction based on the historical quotation data.

Specifically, after the server determines, based on the project requirement information, a research center that undertakes the clinical trial project and a clinical institution management organization that is qualified to execute the clinical trial project at the research center, price data of the clinical institution management organization at the corresponding research center may be acquired based on the clinical institution management organization and the expected corresponding research center. And summarizing the quotation data of each clinical institution management organization in the corresponding research center to obtain cost estimation data.

In the embodiment, the price data of each clinical institution management organization in the corresponding research center is summarized to obtain the cost estimation data of the clinical test project, so that the content of the cost scheme is further enriched, the full scheme content is provided for the sponsor, and the sponsor can conveniently and quickly decide which cost scheme to adopt.

In some embodiments, referring to fig. 7, the cost plan includes a total number of study centers. The marketing estimation data of the product related to the clinical test item includes at least one of the number of research centers that can become marketing points, the proportion data that can become marketing points, and the number of research centers that reach the preset condition of sales share. Wherein, the proportion data is determined by the ratio of the number of research centers which can become marketing distribution points to the total number of the research centers. The display method of the recommendation scheme of the clinical test item can further comprise the following steps: and displaying at least one of the number of research centers capable of becoming marketing points, proportion data capable of becoming marketing points, and the number of research centers meeting preset conditions of sales share.

Wherein the total number of study centers can be understood as the number of study centers that can occasionally undertake clinical trial programs in the cost plan. The total amount of research centers may be an estimated total amount of research centers, the number of research centers specified by the sponsor, or the sum of the estimated total amount of research centers and the number of research centers specified by the sponsor.

Specifically, in some embodiments, a plurality of research centers involved in the cost plan are determined, and the disease source data and/or the sales data of the same type of products of each research center are acquired. And judging whether each research center meets the preset conditions of marketing points according to the disease source data of each research center and/or the sales data of similar products. If satisfied, it would be determined to be a research center that could become a marketing point. So that a research center which can become a marketing point can be determined from a plurality of research centers involved in the cost scheme; and counting the number of research centers capable of becoming marketing points to obtain the number of the research centers capable of becoming marketing points. And calculating the ratio of the number of research centers capable of becoming marketing distribution points to the total number of the research centers, and taking the ratio as the proportion data capable of becoming the marketing distribution points.

And judging whether each research center reaches the preset conditions of the sales share according to the sales data of the similar products of each research center. If so, it may be determined as the research center that reached the preset condition for sales share. And counting the number of the research centers reaching the preset condition of the sales share to obtain the number of the research centers reaching the preset condition of the sales share.

In the embodiment, the number of research centers which can become marketing points, the proportion data which can become marketing points and the number of research centers which reach the preset conditions of sales share are used as marketing estimation data of products related to clinical test projects, and the cost scheme can be accurately estimated based on the marketing estimation data, so that the accuracy of recommending the cost scheme can be improved, and a sponsor can conveniently and quickly decide which cost scheme to adopt.

In some embodiments, the number of cost solutions is multiple. The protocol for presenting clinical trial items may include: a plurality of cost plans for a clinical trial project are presented. In particular, the number of cost solutions is multiple, such as 3. Referring to fig. 8a, the terminal shows scenario 1, scenario 2, and scenario 3. The scheme 1, the scheme 2 and the scheme 3 are respectively provided with recommendation identification information. The recommendation identification information may be information for showing whether to recommend the cost solution to the user, for example, the words "start earliest", "most", "fastest", "higher", and the like shown in fig. 8a may be recommendation identification information for recommending the solution 1. The words "start latest", "least", "lower", "slowest", "lowest", and the like shown in fig. 8a may be recommendation identification information for which no recommendation is made to the scheme 3. Further, since the marketing estimation data and the grouping estimation duration of the scenario 1 are superior to those of the scenarios 2 and 3, recommendation identification information may also be set for the scenario 1 in the form of stars and characters (such as "recommendations").

In some embodiments, the number of cost solutions is multiple. The method may further comprise: in the event that any one of a plurality of cost solutions is triggered, at least part of the information of the triggered cost solution is presented.

Specifically, the terminal displays a plurality of cost schemes, and a user can trigger any one of the cost schemes. Referring to fig. 8b, when the terminal monitors that any one of the plurality of cost solutions is triggered, the terminal may present at least part of the information showing the triggered cost solution.

In the embodiment, at least part of information of the triggered cost scheme is displayed by responding to the trigger operation of any cost scheme, so that the specific content of the cost scheme can be visually displayed for a user, and the operation cost of the user is reduced. Further, the user may also be assisted in making a decision quickly by at least partial information of the presented cost scheme.

In some embodiments, the number of cost solutions is a plurality of the number of cost solutions. The method may further comprise: under the condition that any one of the cost schemes is triggered, showing at least part of information of the triggered cost scheme and a scheme acquisition control; under the condition that the scheme acquisition control is triggered, sending a scheme acquisition request to a server; the scheme obtaining request is used for instructing the server to obtain the scheme details of the cost scheme.

Specifically, the terminal displays a plurality of cost schemes, and a user can trigger any one of the cost schemes. Referring to fig. 8c, when the terminal monitors that any one of the cost solutions is triggered, the terminal may present at least part of the information showing the triggered cost solution and a solution acquisition control. And the terminal monitors the scheme acquisition control, and sends a scheme acquisition request to the terminal under the condition that the scheme acquisition control is triggered. In some embodiments, the server may automatically generate solution details for the cost solution based on the solution acquisition request. In some embodiments, after receiving the scheme acquisition request, the server sends a reminding message to a terminal of a scheme maker, the scheme maker compiles the scheme according to actual conditions, and the terminal of the scheme maker responds to the compiling operation of the cost scheme to acquire the scheme details of the cost scheme. The terminal of the solution maker sends the solution details of the cost solution to the server. And the server acquires the scheme details of the cost scheme. Further, the server may send the solution details of the cost solution to the terminal of the sponsor.

In the embodiment, the specific details of the cost scheme can be visually displayed for the user, the user can directly know the cost scheme in detail through the displayed specific details of the cost scheme, and the user is assisted to make a decision quickly.

The embodiment of the specification provides a display method of a recommendation scheme of a clinical test item, which comprises the following steps.

And S802, providing a requirement information display interface of the clinical test project.

The requirement information display interface is provided with a cost scheme recommendation control and the project requirement information of the clinical test project; the project requirement information is used for determining the achievement scheme of the clinical test project; wherein the cost plan has marketing estimate data for a product involved in the clinical trial program and an estimated length of time to group for the subject required for the clinical trial program.

In some embodiments, the project requirement information comprises indication data, number of subjects; wherein a study center that undertakes the clinical trial project is determined based on the indication data and the number of subjects; wherein the research center has incidence relation data; wherein a clinical institution management organization at the research center eligible to execute the clinical trial project is determined based on the incidence relation data; wherein the cost plan includes an estimated total for the research center and an estimated total for the clinical institution management organization.

In some embodiments, the project requirement information further includes a project name; wherein a study center that undertakes the clinical trial program is determined based on the indication data, the program name, and the number of subjects.

In some embodiments, the project requirement information includes a sponsor-specified research center capable of undertaking the clinical trial project; wherein the research center has incidence relation data; wherein the incidence relation data comprises relation data of a research center and a clinical institution management organization; a clinical institution management organization at the research center eligible to perform the clinical trial project is determined based on the incidence relation data; wherein the cost plan includes an estimated total amount of the clinical institution management organization.

In some embodiments, the cost plan further includes cost estimation data. And the cost estimation data is obtained by summarizing price quotation data of the clinical institution management organization in the corresponding research center.

S804, under the condition that the cost scheme recommendation control is triggered, displaying the cost scheme and the recommendation identification information of the cost scheme of the clinical test item; wherein the recommendation identification information is determined based on the marketing evaluation data and the grouping estimated duration.

In some embodiments, the cost plan includes a total number of research centers; the marketing estimation data of the product related to the clinical test item comprises at least one of the number of research centers capable of becoming marketing points, the proportion data capable of becoming marketing points and the number of research centers reaching the preset condition of sales share; wherein the proportion data is determined by the ratio of the number of research centers capable of becoming marketing distribution points to the total number of the research centers.

And S806, displaying at least one of the number of research centers capable of becoming marketing points, proportion data capable of becoming marketing points and the number of research centers reaching preset conditions of sales share.

And S808, displaying the grouping estimated time length of all the subjects required by the clinical test item.

S810, displaying the research starting time of the clinical test item; wherein the study start time is the start time of the study center that started the clinical trial project earliest.

Referring to fig. 9, the present specification provides a method for generating a recommendation scheme of a clinical test item, which is applied to a server, and the method for generating the recommendation scheme of the clinical test item may include the following steps.

S910, receiving project requirement information of the clinical test project.

S920, generating a plurality of cost schemes of the clinical test items based on the item demand information.

Wherein the cost plan has marketing estimate data for a product involved in the clinical trial program and an estimated length of time to group for the subject required for the clinical trial program.

And S930, determining a recommendation scheme in each achievement scheme according to the marketing estimation data of each achievement scheme and the grouping estimation duration.

And S940, sending the completed scheme of the clinical test project to a client so that the client can display at least part of the received cost scheme.

And the recommendation scheme in the displayed cost scheme has recommendation identification information.

In some embodiments, the project requirement information comprises indication data, number of subjects. The method for generating the recommendation of clinical trial items may further include the following steps.

S1010, determining a research center capable of bearing the clinical test item based on the indication data and the number of the subjects.

Wherein the research center has incidence relation data.

S1020, determining a clinical institution management organization qualified to execute the clinical trial project in the research center according to the incidence relation data.

Wherein the cost plan includes an estimated total volume for the research center and an estimated total volume for the clinical institution management organization.

In some embodiments, the project requirement information further includes a project name; the determining a study center capable of undertaking the clinical trial project based on the indication data and the number of subjects may include: determining a study center capable of undertaking the clinical trial program based on the indication data, the program name, and the number of subjects.

In some embodiments, the project requirement information includes a sponsor-specified research center capable of undertaking the clinical trial project; wherein the research center has incidence relation data; the incidence relation data comprises relation data of a research center and a clinical institution management organization; the method for generating the recommendation scheme of the clinical test item can further comprise the following steps: determining a clinical institution administrative organization qualified to execute the clinical trial project at the research center based on the association data. Wherein the cost plan includes an estimated total volume for the research center and an estimated total volume for the clinical institution management organization.

In some embodiments, the method for generating a recommendation of a clinical trial item may further include the steps of: and summarizing the quotation data of each clinical institution management organization in the corresponding research center to obtain the cost estimation data of the clinical trial project. Wherein the cost plan further comprises the cost estimate data.

In some embodiments, the method of generating a recommendation of a clinical trial project protocol may further include the following steps.

And S1110, determining the research center capable of becoming a marketing point among the plurality of research centers involved in the cost scheme.

And S1120, acquiring the ratio of the number of the research centers capable of becoming marketing points to the total number of the research centers, and taking the ratio as the proportion data capable of becoming marketing points.

And S1130, determining the number of the research centers which reach the preset condition of the sales share in the plurality of research centers related to the cost scheme.

Wherein the marketing estimation data for the product to which the clinical trial project relates includes at least one of a number of research centers that can become marketing points, and proportion data that can become marketing points.

The embodiment of the specification provides a method for generating a recommendation scheme of a clinical test item. The method for generating the recommendation scheme of the clinical test items comprises the following steps.

And S1202, receiving the project requirement information of the clinical test project.

Wherein the project requirement information comprises indication data, the number of subjects and project names.

And S1204, determining the success scheme of the clinical test project based on the project requirement information.

Wherein the cost plan has marketing estimate data for a product involved in the clinical trial project and a group estimate of length of time of admission of the subject required for the clinical trial project.

And S1206, generating recommendation identification information of the cost scheme according to the marketing estimation data and the grouping estimation duration.

And S1208, returning the completion scheme of the clinical test item and the recommendation identification information of the cost scheme to the client.

S1210, determining a research center capable of bearing the clinical test item based on the indication data, the item name and the number of the subjects; wherein the research center has incidence relation data.

S1212, determining a clinical institution management organization qualified to execute the clinical trial project in the research center according to the incidence relation data.

And S1214, summarizing the quotation data of the clinical institution management organizations in the corresponding research centers to obtain the cost estimation data of the clinical test projects.

Wherein the cost plan further comprises the cost estimate data.

S1216, determining a research center capable of becoming a marketing point among the plurality of research centers involved in the cost plan.

And S1218, acquiring a ratio of the number of research centers capable of becoming marketing points to the total number of the research centers, and taking the ratio as percentage data capable of becoming marketing points.

And S1220, determining the number of the research centers reaching the preset condition of the sales share among the plurality of research centers involved in the cost scheme.

For specific limitations on the method for generating the recommendation scheme of the clinical trial items applied to the server, reference may be made to the above limitations on the presentation method of the recommendation scheme of the clinical trial items applied to the client, and details are not repeated here. The client of the embodiments of the present specification may be an electronic device having a network access capability. Specifically, for example, the client may be a desktop computer, a tablet computer, a notebook computer, a smart phone, a digital assistant, a smart wearable device, a shopping guide terminal, a television, a smart speaker, a microphone, and the like. Wherein, wearable equipment of intelligence includes but not limited to intelligent bracelet, intelligent wrist-watch, intelligent glasses, intelligent helmet, intelligent necklace etc.. Alternatively, the client may be software that can run in the electronic device.

It should be understood that, although the steps in the above-described flowcharts are shown in order as indicated by the arrows, the steps are not necessarily performed in order as indicated by the arrows. The steps are not performed in the exact order shown and described, and may be performed in other orders, unless explicitly stated otherwise. Moreover, at least a part of the steps in the above-mentioned flowcharts may include a plurality of steps or a plurality of stages, which are not necessarily performed at the same time, but may be performed at different times, and the order of performing the steps or the stages is not necessarily performed in sequence, but may be performed alternately or alternately with other steps or at least a part of the steps or the stages in other steps.

Referring to fig. 10, an embodiment of the present disclosure provides a device for displaying a recommendation scheme of a clinical trial item, applied to a client, the device including: the system comprises a display interface providing module, a demand information sending module, a cost scheme receiving module and a cost scheme display module.

The display interface providing module is used for providing a requirement information display interface of the clinical test project; the requirement information display interface is provided with a cost scheme recommendation control and the item requirement information of the clinical test items.

The requirement information sending module is used for sending the project requirement information to a server under the condition that the cost scheme recommendation control is triggered; wherein the project requirement information is used for instructing the server to generate a plurality of cost schemes of the clinical test project; wherein the cost plan has marketing estimate data for a product involved in the clinical trial program and an estimated length of time to group for a subject required for the clinical trial program; determining a recommendation among each of the achievements based on the marketing evaluation data and the grouping evaluation duration of the each of the achievements.

And the cost scheme receiving module is used for receiving the cost scheme of the clinical test project sent by the server.

The cost scheme display module is used for displaying at least part of the received cost scheme; wherein the displayed cost scheme comprises the recommendation scheme, and the recommendation scheme is provided with recommendation identification information.

For specific definition of the presentation apparatus of the recommendation scheme of the clinical trial item, reference may be made to the above definition of the presentation method of the recommendation scheme of the clinical trial item, and details are not repeated here. The modules in the recommendation device for clinical trial project schemes described above may be implemented in whole or in part by software, hardware, and combinations thereof. The modules can be embedded in a hardware form or independent from a processor in the computer device, and can also be stored in a memory in the computer device in a software form, so that the processor can call and execute operations corresponding to the modules.

Referring to fig. 11, an embodiment of the present disclosure provides an apparatus for generating a recommendation scheme of a clinical trial item, applied to a server, the apparatus including: the system comprises a demand information receiving module, a cost scheme determining module, a recommendation scheme determining module and a cost scheme returning module.

And the requirement information receiving module is used for receiving the project requirement information of the clinical test project.

A cost plan determination module for determining a cost plan for the clinical trial project based on the project requirement information; wherein the cost plan has marketing estimate data for a product involved in the clinical trial program and an estimated length of time to group for the subject required for the clinical trial program.

And the recommendation scheme determining module is used for determining a recommendation scheme in each achievement scheme according to the marketing estimation data of each achievement scheme and the grouping estimation duration.

The cost scheme returning module is used for sending the cost scheme of the clinical test project to a client so that the client can display at least part of the received cost scheme; wherein the displayed cost scheme comprises the recommendation scheme, and the recommendation scheme is provided with recommendation identification information.

For specific limitations of the apparatus for generating the recommendation scheme of the clinical trial item, reference may be made to the above limitations of the method for generating the recommendation scheme of the clinical trial item, and details thereof are not repeated here. The modules in the recommendation device for clinical trial project schemes described above may be implemented in whole or in part by software, hardware, and combinations thereof. The modules can be embedded in a hardware form or independent from a processor in the computer device, and can also be stored in a memory in the computer device in a software form, so that the processor can call and execute operations corresponding to the modules.

In some embodiments, a computer device is provided, which may be a terminal, and its internal structure diagram may be as shown in fig. 12. The computer device includes a processor, a memory, a communication interface, a display screen, and an input device connected by a system bus. Wherein the processor of the computer device is configured to provide computing and control capabilities. The memory of the computer device comprises a nonvolatile storage medium and an internal memory. The non-volatile storage medium stores an operating system and a computer program. The internal memory provides an environment for the operation of an operating system and computer programs in the non-volatile storage medium. The communication interface of the computer device is used for carrying out wired or wireless communication with an external terminal, and the wireless communication can be realized through WIFI, an operator network, NFC (near field communication) or other technologies. The computer program is executed by a processor to implement a method of presenting or generating a recommendation for a clinical trial item. The display screen of the computer equipment can be a liquid crystal display screen or an electronic ink display screen, and the input device of the computer equipment can be a touch layer covered on the display screen, a key, a track ball or a touch pad arranged on the shell of the computer equipment, an external keyboard, a touch pad or a mouse and the like.

Those skilled in the art will appreciate that the architecture shown in fig. 12 is merely a block diagram of some of the structures associated with the disclosed aspects and is not intended to limit the computing device to which the disclosed aspects apply, and that a computing device may in particular include more or less components than those shown, or combine certain components, or have a different arrangement of components.

In some embodiments, a computer device is provided, comprising a memory having a computer program stored therein and a processor that, when executing the computer program, performs the method steps of the above embodiments.

In some embodiments, a computer-readable storage medium is provided, on which a computer program is stored, which when executed by a processor implements the method steps in the above-described embodiments.

In some embodiments, a computer program product is also provided, which comprises instructions that are executable by a processor of a computer device to implement the method steps in the above-described embodiments.

It will be understood by those skilled in the art that all or part of the processes of the methods of the embodiments described above can be implemented by hardware instructions of a computer program, which can be stored in a non-volatile computer-readable storage medium, and when executed, can include the processes of the embodiments of the methods described above. Any reference to memory, storage, database, or other medium used in the various embodiments provided herein can include at least one of non-volatile and volatile memory. Non-volatile Memory may include Read-Only Memory (ROM), magnetic tape, floppy disk, flash Memory, optical storage, or the like. Volatile Memory can include Random Access Memory (RAM) or external cache Memory. By way of illustration and not limitation, RAM can take many forms, such as Static Random Access Memory (SRAM) or Dynamic Random Access Memory (DRAM), among others.

The features of the above embodiments may be arbitrarily combined, and for the sake of brevity, all possible combinations of the features in the above embodiments are not described, but should be construed as being within the scope of the present specification as long as there is no contradiction between the combinations of the features.

The above description is only for the purpose of illustrating the preferred embodiments of the present disclosure and is not to be construed as limiting the present disclosure, and any modifications, equivalents and the like that are within the spirit and principle of the present disclosure are intended to be included within the scope of the present disclosure.

Claims

1. A method for displaying a recommendation scheme of a clinical test item is applied to a client side, and comprises the following steps:

providing a requirement information display interface of the clinical test item; the requirement information display interface is provided with a cost scheme recommendation control and the project requirement information of the clinical test project; the project requirement information comprises at least one project parameter, and the project parameter comprises indication data, project staging names and target group entry case numbers;

sending the project requirement information to a server under the condition that the cost scheme recommendation control is triggered; wherein the project requirement information is used for instructing the server to generate a plurality of cost schemes of the clinical test project; wherein the cost plan has marketing estimate data for a product involved in the clinical trial program and an estimated length of time to group for a subject required for the clinical trial program; determining a recommended plan in each of the achievement plans based on the marketing estimation data and the grouping estimation duration of each of the achievement plans; wherein, the marketing estimation data is determined in a manner that: determining a research center capable of bearing clinical test projects based on the indication data, the project staging names and the target group entering cases; acquiring at least one of disease source data of a research center capable of bearing clinical test projects and sales data of similar products; determining the marketing evaluation data based on the source data and/or sales data for the same type of product; wherein the determining a recommended plan in each of the achievement plans based on the marketing estimation data and the grouping estimation duration of each of the achievement plans includes: determining the recommendation index of each solution according to the marketing estimation data weight ratio, the grouping estimation time length weight ratio, the marketing estimation data and the grouping estimation time length; recommending the solution with the highest index as a recommended solution;

receiving the clinical test project completion scheme sent by the server;

presenting at least part of the received cost plan; wherein the displayed cost scheme comprises the recommendation scheme, and the recommendation scheme is provided with recommendation identification information;

the server is stored with relationship data between the name of the research center and historical disease source data in advance; generating a number of cost plans for the clinical trial project, including:

inquiring relation data between the research center names and historical disease source data according to a plurality of research center names corresponding to the project requirement information; determining the number of subjects which can be recruited by the initial research centers corresponding to the plurality of research center names according to the query result; determining a research center capable of bearing clinical test projects from the preliminary research centers corresponding to the names of a plurality of research centers on the basis of the target grouping number and the number of the subjects capable of being recruited by the preliminary research centers;

matching in the incidence relation data set according to the identification information of the research center capable of bearing the clinical test items, and determining the clinical institution management organization corresponding to the research center; the clinical institution management organization corresponding to the incidence relation data has qualification for executing clinical test items in the research center corresponding to the incidence relation data;

calculating based on historical data of similar clinical test projects executed by clinical institution management organizations and/or historical data of similar clinical test projects executed by research centers to obtain group-entering estimated time of all subjects required by the clinical test projects and/or research starting time of the clinical test projects;

and determining the finished scheme of the clinical test project based on the cost estimation data of the clinical test project, the estimated total amount of the clinical institution management organization, the estimated total amount of the research center, the grouping estimated time and the research starting time of the clinical test project.

2. The method of claim 1, further comprising:

the estimated time to group for all subjects required for the clinical trial project is presented.

3. The method of claim 1, wherein the cost estimate data is aggregated based on quote data for each of the clinical institution management organizations at the corresponding research centers.

4. The method of claim 1, wherein the cost plan includes a total number of research centers; the marketing estimation data of the product related to the clinical test item comprises at least one of the number of research centers capable of becoming marketing points, the proportion data capable of becoming marketing points and the number of research centers reaching the preset condition of sales share; wherein the proportion data is determined by the ratio of the number of research centers capable of becoming marketing distribution points to the total number of the research centers; the method further comprises the following steps:

and displaying at least one of the number of research centers capable of becoming marketing points, proportion data capable of becoming marketing points, and the number of research centers meeting preset conditions of sales share.

5. The method of claim 1, further comprising:

displaying study start time of the clinical trial project; wherein the study start time is the start time of the study center that initiated the clinical trial project earliest.

6. The method of claim 1, wherein the number of cost solutions is plural; the method further comprises at least one of:

in the event that any one of a plurality of said cost solutions is triggered, presenting at least part of the information of the triggered cost solution; or

In the case that any one of a plurality of cost schemes is triggered, showing at least part of information of the triggered cost scheme and a scheme acquisition control; under the condition that the scheme acquisition control is triggered, sending a scheme acquisition request to a server; wherein the scheme obtaining request is used for instructing the server to obtain the scheme details of the cost scheme.

7. A method for generating a recommendation scheme of a clinical test item, which is applied to a server, is characterized by comprising the following steps:

receiving project requirement information of the clinical test project; the project requirement information comprises at least one project parameter, and the project parameter comprises indication data, project staging names and target group entry case numbers;

generating a number of cost plans for the clinical trial project based on the project requirement information; wherein the cost plan has marketing estimate data for a product involved in the clinical trial program and an estimated length of time to group for a subject required for the clinical trial program; wherein, the marketing estimation data is determined in a manner that: determining a research center capable of bearing clinical test projects based on the indication data, the project staging names and the target group entering cases; acquiring at least one of disease source data of a research center capable of bearing clinical test projects and sales data of similar products; determining the marketing evaluation data based on the source data and/or sales data for the same type of product;

determining a recommendation index of each solution according to the marketing estimated data weight ratio, the grouping estimated time weight ratio, the marketing estimated data of each solution and the grouping estimated time, and determining the solution with the highest recommendation index in each solution as a recommendation solution;

sending the completed scheme of the clinical trial project to a client so that the client displays at least part of the received cost scheme; the recommendation scheme in the displayed cost scheme has recommendation identification information;

matching in the incidence relation data set according to the identification information of the research center capable of bearing the clinical test items, and determining the clinical institution management organization corresponding to the research center; the clinical institution management organization corresponding to the incidence relation data has qualification for executing clinical test projects in the research center corresponding to the incidence relation data;

8. An apparatus for displaying a recommendation scheme of a clinical trial item, applied to a client, the apparatus comprising:

the display interface providing module is used for providing a requirement information display interface of the clinical test project; the requirement information display interface is provided with a cost scheme recommendation control and the project requirement information of the clinical test project; the project requirement information comprises at least one project parameter, and the project parameter comprises indication data, project staging names and target group entry case numbers;

the requirement information sending module is used for sending the project requirement information to a server under the condition that the cost scheme recommendation control is triggered; wherein the project requirement information is used for instructing the server to generate a plurality of cost schemes of the clinical test project; wherein the cost plan has marketing estimate data for a product involved in the clinical trial program and an estimated length of time to group for a subject required for the clinical trial program; determining a recommended plan in each of the achievement plans based on the marketing estimation data and the grouping estimation duration of each of the achievement plans; wherein, the marketing estimation data is determined in a manner that: determining a research center capable of bearing clinical test projects based on the indication data, the project staging names and the target group entering cases; acquiring at least one of disease source data of a research center capable of bearing clinical test projects and sales data of similar products; determining the marketing evaluation data based on the source data and/or sales data for the same type of product; wherein the determining a recommended plan in each of the achievement plans based on the marketing estimation data and the grouping estimation duration of each of the achievement plans includes: determining the recommendation index of each solution according to the marketing estimation data weight ratio, the grouping estimation time length weight ratio, the marketing estimation data and the grouping estimation time length; recommending the solution with the highest index as a recommended solution;

the cost scheme receiving module is used for receiving the clinical test project completion scheme sent by the server;

the cost scheme display module is used for displaying at least part of the received cost scheme; wherein the displayed cost scheme comprises the recommended scheme, and the recommended scheme is provided with recommended identification information;

calculating based on historical data of similar clinical test projects executed by a clinical institution management organization and/or historical data of similar clinical test projects executed by a research center to obtain grouping estimated time of all subjects required by the clinical test projects and/or research starting time of the clinical test projects;

9. An apparatus for generating a recommendation scheme for clinical trial items, applied to a server, the apparatus comprising:

the requirement information receiving module is used for receiving the project requirement information of the clinical test project;

a cost plan determination module for generating a cost plan for the clinical trial project based on the project requirement information; wherein the cost plan has marketing estimate data for a product involved in the clinical trial program and an estimated length of time to group for a subject required for the clinical trial program; wherein, the marketing estimation data is determined in a manner that: determining a research center capable of bearing clinical test projects based on the indication data, the project staging names and the target group entering cases; acquiring at least one of disease source data of a research center capable of bearing clinical test projects and sales data of similar products; determining the marketing evaluation data based on the source data and/or sales data for the same type of product;

a recommendation scheme determining module, configured to determine a recommendation index of each solution according to a marketing estimation data weight ratio, an enrollment estimation time length weight ratio, marketing estimation data of each solution, and the enrollment estimation time length, and determine a solution with a highest recommendation index among the solutions as a recommendation scheme;

the cost scheme returning module is used for sending the cost scheme of the clinical test project to a client so that the client can display at least part of the received cost scheme; wherein the displayed cost scheme comprises the recommended scheme, and the recommended scheme is provided with recommended identification information;

10. A computer device comprising a memory and a processor, the memory storing a computer program, characterized in that the processor, when executing the computer program, implements the steps of the method of any of claims 1 to 7.

11. A computer-readable storage medium, on which a computer program is stored, which, when being executed by a processor, carries out the steps of the method of any one of claims 1 to 7.