CN114225474A - Solid-state extraction element of western medicine medicament - Google Patents
Solid-state extraction element of western medicine medicament Download PDFInfo
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- CN114225474A CN114225474A CN202210075067.6A CN202210075067A CN114225474A CN 114225474 A CN114225474 A CN 114225474A CN 202210075067 A CN202210075067 A CN 202210075067A CN 114225474 A CN114225474 A CN 114225474A
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- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/22—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the construction of the column
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Abstract
The invention belongs to the technical field of medicament extraction, and particularly relates to a solid-state extraction device for western medicament; comprises a fixed bed body; the fixed bed body includes: a liquid inlet pipe; the liquid inlet pipe is fixedly connected to the upper surface of the fixed bed body; a liquid outlet pipe; the liquid outlet pipe is fixedly connected to the lower surface of the fixed bed body; a material changing unit; the material changing unit is arranged in the fixed bed body; an adsorbent; a blanking unit; the blanking unit is arranged on the outer surface of the fixed bed body and is communicated with the blanking cavity; a feeding unit; the feeding unit is arranged on the outer surface of the fixed bed body and communicated with the feeding cavity; the invention mainly solves the problem that when the expanded column bed adsorption technology is used for adsorption and extraction at present, the adsorption effect of the adsorbent can be reduced even the adsorbent does not have the adsorption effect after the adsorbent in the fixed bed used in the expanded column bed adsorption technology is fully adsorbed and saturated, but the adsorption work of the fixed bed needs to be stopped when a new adsorbent is replaced, so that the adsorption efficiency is reduced.
Description
Technical Field
The invention belongs to the technical field of medicament extraction, and particularly relates to a solid-state extraction device for western medicament.
Background
Since the introduction of western medicines into China, the rapid development of medicine and pharmacology in China is driven, and in long-term development, various western medicine preparation technologies are formed, wherein an extraction, separation and purification technology is an advanced medicine preparation technology.
In the preparation of the medicine, an extraction technology and a separation and purification technology are common medicine preparation technologies, and the extraction technology and the separation and purification technology are widely applied to western medicines and also have great application values in the preparation of traditional Chinese medicine preparations. The extraction technology mainly has the effects of extracting the components with the drug effect from the medicinal materials and improving the purity of the medicinal materials by utilizing the separation and purification technology, so that the effective components are concentrated, and a good foundation is laid for the subsequent preparation of the medicine.
Different from the preparation of traditional Chinese medicines, the preparation of western medicines has higher requirements on process links because the ingredients of the western medicines are more chemical ingredients, and if the ingredients of the western medicines are not accurately held in the process links, the medicine effect of the western medicines can be greatly influenced. Therefore, western medicines attach more importance to the application of the extraction, separation and purification technology and have relatively high requirements. At present, in the preparation of western medicines, the used mature extraction, separation and purification technologies mainly comprise three technologies, namely an expanded column bed adsorption technology, a radial membrane chromatography technology and a perfusion chromatography technology. The three extraction, separation and purification technologies have obvious advantages in operation, separation efficiency or separation capacity, and are western medicine preparation technologies with great development prospects. In the following, we will discuss their respective specific applications in preparing western medicines.
The expanded bed adsorption chromatography technique combines the advantages of both fluidized bed and packed bed chromatography and allows the adsorption of the desired product directly from the feed without prior removal of particles from the feed. It is a separation and purification technology with integration advantage, and has very wide application prospect in the downstream processing process of bioengineering products. The development of a good performing adsorbent matrix is a key to the widespread use of this technology.
The solid-state extraction process of a medicament commonly used in the prior art is an expanded column bed adsorption technology, however, when the expanded column bed adsorption technology is used for adsorption and extraction, after the adsorbent in a fixed bed used in the expanded column bed adsorption technology is fully adsorbed and saturated, the adsorption effect of the adsorbent can be reduced, or even the adsorbent does not have the adsorption effect, so that the adsorbent needs to be replaced periodically and manually, and when a new adsorbent is replaced, the adsorption work of the fixed bed needs to be stopped, thereby reducing the adsorption efficiency.
In view of this, in order to overcome the above technical problems, the present invention provides a solid-state extraction device for western medicine, which solves the above technical problems.
Disclosure of Invention
In order to make up for the defects of the prior art, the invention provides a solid-state extraction device for western medicine medicaments, which is mainly used for solving the problems that when the expanded column bed adsorption technology is used for adsorption extraction at present, after an adsorbent in a fixed bed used in the expanded column bed adsorption technology is fully adsorbed and saturated, the adsorption effect of the adsorbent is reduced, even the adsorbent does not have the adsorption effect, so that the adsorbent needs to be replaced periodically and manually, and when a new adsorbent is replaced, the adsorption work of the fixed bed needs to be stopped, so that the adsorption efficiency is reduced.
The technical scheme adopted by the invention for solving the technical problems is as follows: the invention relates to a solid-state extraction device for western medicine medicament, which comprises
A fixed bed body; the fixed bed body includes:
a liquid inlet pipe; the liquid inlet pipe is fixedly connected to the upper surface of the fixed bed body and is used for introducing feed liquid to be adsorbed;
a liquid outlet pipe; the liquid outlet pipe is fixedly connected to the lower surface of the fixed bed body and used for leading out the adsorbed liquid;
a detector; the detector is arranged on the liquid outlet pipe and is used for detecting the change of the concentration of the solute in the feed liquid;
a material changing unit; the material changing unit is arranged in the fixed bed body and divides the fixed bed body into an adsorption cavity, a discharging cavity and a feeding cavity; the liquid inlet pipe and the liquid outlet pipe are both communicated with the adsorption cavity;
an adsorbent; the adsorbent is one of active carbon or ion exchange resin, and is placed in the adsorption cavity and used for substances in the feed liquid;
a blanking unit; the blanking unit is arranged on the outer surface of the fixed bed body and communicated with the blanking cavity, and the blanking unit is used for unloading the adsorbent with saturated adsorption;
a feeding unit; the feeding unit is arranged on the outer surface of the fixed bed body and communicated with the feeding cavity, and the feeding unit is used for placing unused adsorbent;
a controller; the controller is used for controlling the material changing unit, the blanking unit and the feeding unit.
Preferably, the reloading unit comprises:
a rotating rod; the rotating rod is rotatably connected to the central point of the fixed bed body;
a baffle plate; the number of the baffle plates is three, and the baffle plates are fixedly connected with the outer surface of the rotating rod; one side of the rotating rod, which is far away from the rotating rod, is attached to the inner wall of the fixed bed body;
a first motor; the first motor is fixedly connected to the lower surface of the fixed bed body, and the rotating rod is fixedly connected with a rotating shaft of the first motor through a coupling;
the unloading unit includes:
a first storage box; the first storage box is fixedly connected with the outer surface of the fixed bed body, and a box cover is arranged at the top of the first storage box; the first storage box corresponds to the blanking cavity;
a discharging groove; a blanking groove is formed in the inner wall of the fixed bed body in the blanking cavity and is communicated with the first storage box;
the material loading unit comprises:
a second storage box; the second storage tank is fixedly connected with the outer surface of the fixed bed body, and unused adsorbent is placed in the second storage tank; the top of the second storage box is provided with a box cover; the second storage box corresponds to the feeding cavity;
a feeding trough; a feeding groove is formed in the inner wall of the fixed bed body in the feeding cavity and is communicated with the second storage box;
a limiting cylinder; the limiting cylinder is fixedly connected with the outer surface of the fixed bed body and surrounds the feeding groove;
the packing auger is rotatably connected in the limiting cylinder and is driven by a motor.
Preferably, every two adjacent one sides of baffle all link firmly the filter plate of evenly arranging jointly, and the filter plate designs for upwards inclining to fixed bed body surface one side.
Preferably, the feeding cavity and the inner wall of the fixed bed body are provided with uniformly arranged feeding troughs, and the lowest point of each feeding trough is flush with the highest point of the corresponding filter plate.
Preferably, two rotating shafts are rotatably connected to the inner wall of each filter plate through two motors; two same filter screen is twined on the pivot.
Preferably, the rotating shaft wound by each filter screen is fixedly connected with uniformly arranged felting needles.
Preferably, the outer surface of the filter screen is fixedly connected with uniformly arranged parting beads.
Preferably, each filter plate is higher at two sides than at the middle bottom.
The invention has the following beneficial effects:
1. after the adsorbent saturation, the controller control unit anticlockwise rotation of reloading this moment, at unit pivoted in-process of reloading, can drive the saturated adsorbent that adsorbs and rotate to the unloading intracavity, adsorbent after the saturation can fall into the unloading unit when the adsorbent rotates to the unloading intracavity, simultaneously at unit pivoted in-process of reloading, can drive the adsorbent that the material loading unit sent into the material loading intracavity and change over to the absorption intracavity, can carry out automatic reloading under the adsorbed condition of not stopping at this in-process, thereby manual reloading when can avoiding stopping adsorbing.
2. Because the baffle both sides are equipped with the filter plate of tilt up, after the feed liquid passes through the feed liquor pipe and gets into the adsorption cavity, the feed liquid can fall on the filter plate, because the filter plate slope to can make the feed liquid flow on the filter plate, speed when this in-process can reduce the feed liquid whereabouts can increase the contact of feed liquid and adsorbent for a long time, thereby improve the adsorption effect of adsorbent to the feed liquid, a plurality of filter plates can also make the adsorbent layering simultaneously, prevent that the adsorbent from piling up the mobility that influences the feed liquid on a large scale.
3. Because there is the filter screen through the winding of pivot in the filter plate, at the in-process of adsorbent absorption feed liquid, the motor that bull stick one side was kept away from in controller control rotates, can drive the filter screen at motor pivoted in-process and remove and twine the filter screen, can make the adsorbent take place to remove at this in-process and roll even, thereby can make the adsorbent trade the face and adsorb, thereby make the adsorbent adsorb comprehensively, improve adsorption effect, simultaneously can also prevent that the adsorbent from piling up the removal effect that influences the feed liquid, simultaneously when needs carry out the unloading to the adsorbent that adsorbs the saturation, the motor that rotates to keep away from bull stick one side at this moment can drive the filter screen and remove, can take away the adsorbent at the in-process that the filter screen removed from, prevent that the filter plate from staying on the filter plate, influence material loading.
Drawings
The invention will be further explained with reference to the drawings.
FIG. 1 is a perspective view of the present invention;
FIG. 2 is a top view of the present invention;
FIG. 3 is a cross-sectional view taken at A-A of FIG. 2 in accordance with the present invention;
FIG. 4 is a cross-sectional view taken at B-B of FIG. 2 in accordance with the present invention;
FIG. 5 is an enlarged view of a portion of the invention at C of FIG. 3;
FIG. 6 is a schematic view of a filter plate according to the present invention;
in the figure:
1. a fixed bed body; 11. a liquid inlet pipe; 12. a liquid outlet pipe; 13. an adsorption chamber; 14. a blanking cavity; 15. a feeding cavity; 2. a material changing unit; 21. a rotating rod; 22. a baffle plate; 23. a first motor; 24. filtering the plate; 25. a rotating shaft; 26. a filter screen; 27. a needle; 28. a parting strip; 3. a blanking unit; 31. a first storage box; 32. a discharging groove; 4. a feeding unit; 41. a second storage box; 42. a feeding trough; 43. a limiting cylinder; 44. and (4) a packing auger.
Detailed Description
As shown in figures 1-6, the solid-state extraction device for western medicine medicament of the present invention comprises
A fixed bed body 1; the fixed bed body 1 includes:
a liquid inlet pipe 11; the liquid inlet pipe 11 is fixedly connected to the upper surface of the fixed bed body 1, and the liquid inlet pipe 11 is used for introducing liquid to be adsorbed;
a liquid outlet pipe 12; the liquid outlet pipe 12 is fixedly connected to the lower surface of the fixed bed body 1, and the liquid outlet pipe 12 is used for guiding out the adsorbed liquid;
a detector; the detector is arranged on the liquid outlet pipe 12 and is used for detecting the change of the concentration of the solute in the feed liquid;
a material changing unit 2; the material changing unit 2 is arranged in the fixed bed body 1, and the fixed bed body 1 is divided into an adsorption cavity 13, a discharging cavity 14 and a feeding cavity 15 by the material changing unit 2; the liquid inlet pipe 11 and the liquid outlet pipe 12 are both communicated with the adsorption cavity 13;
an adsorbent; the adsorbent is one of active carbon or ion exchange resin, is placed in the adsorption cavity 13 and is used for substances in the feed liquid;
a blanking unit 3; the blanking unit 3 is arranged on the outer surface of the fixed bed body 1 and is communicated with the blanking cavity 14, and the blanking unit 3 is used for unloading the adsorbent saturated in adsorption;
a feeding unit 4; the feeding unit 4 is arranged on the outer surface of the fixed bed body 1 and is communicated with the feeding cavity 15, and the feeding unit 4 is used for placing unused adsorbent;
a controller; the controller is used for controlling the material changing unit 2, the blanking unit 3 and the feeding unit 4;
the conventional solid-state extraction process of the medicament in the prior art is an expanded column bed adsorption technology, however, when the expanded column bed adsorption technology is used for adsorption and extraction, after the adsorbent in a fixed bed used in the expanded column bed adsorption technology is fully adsorbed and saturated, the adsorption effect of the adsorbent is reduced, even the adsorbent does not have the adsorption effect, so that the adsorbent needs to be replaced periodically and manually, and when a new adsorbent is replaced, the adsorption work of the fixed bed needs to be stopped, so that the adsorption efficiency is reduced;
when the invention is used, firstly, the adsorbent is placed in the adsorption cavity 13 which is separated by the material changing unit 2 in the fixed bed body 1, and new adsorbent is placed in the material feeding unit 4, then the material feeding unit 4 is controlled by the controller to work, in the working process of the material feeding unit 4, the new adsorbent in the material feeding unit 4 can be sent into the material feeding cavity 15 which is formed by the material changing unit 2, then the fixed bed is started, the material liquid to be adsorbed is introduced into the adsorption cavity 13 which is separated by the material changing unit 2 in the fixed bed body 1 through the liquid inlet pipe 11, when the material liquid passes through the adsorbent in the adsorption cavity 13, the adsorbent can adsorb and extract the material liquid, the adsorbed material liquid flows out of the adsorption cavity 13 through the liquid outlet pipe 12, when the adsorbed material liquid passes through the detector, the detector can detect the change of solute concentration in the outflow material liquid, thereby detecting the saturation condition of the adsorbent through the change of concentration, after the adsorbent saturation, controller control unit 2 anticlockwise rotation reloads this moment, at unit 2 pivoted in-process reloads, can drive the saturated adsorbent that adsorbs and rotate to unloading chamber 14 in, adsorbent after the saturation can fall into unloading unit 3 when the adsorbent rotates to unloading chamber 14 in, simultaneously at unit 2 pivoted in-process reloads, can drive material loading unit 4 and send into the adsorbent in material loading chamber 15 and change over to in adsorbing chamber 13, can carry out automatic reloading under the adsorbed condition of not stopping at this in-process, thereby manual reloading when can avoid stopping adsorbing.
As an embodiment of the present invention, the refueling unit 2 includes:
a rotary rod 21; the rotating rod 21 is rotatably connected to the central point of the fixed bed body 1;
a baffle 22; the number of the baffle plates 22 is three, and the baffle plates are fixedly connected with the outer surface of the rotating rod 21; one side of the rotating rod 21, which is far away from the rotating rod 21, is attached to the inner wall of the fixed bed body 1;
a first motor 23; the first motor 23 is fixedly connected to the lower surface of the fixed bed body 1, and the rotating rod 21 is fixedly connected with a rotating shaft of the first motor 23 through a coupling;
the blanking unit 3 includes:
a first storage box 31; the first storage box 31 is fixedly connected with the outer surface of the fixed bed body 1, and a box cover is arranged at the top of the first storage box 31; the first storage box 31 corresponds to the blanking cavity 14;
a discharge chute 32; a blanking groove 32 is formed in the inner wall of the fixed bed body 1 in the blanking cavity 14, and the blanking groove 32 is communicated with the first storage box 31;
the feeding unit 4 includes:
a second storage box 41; the second storage tank 41 is fixedly connected with the outer surface of the fixed bed body 1, and unused adsorbent is placed in the second storage tank 41; a box cover is arranged at the top of the second storage box 41; the second storage box 41 corresponds to the feeding cavity 15;
a feeding chute 42; a feeding groove 42 is formed in the inner wall of the fixed bed body 1 in the feeding cavity 15, and the feeding groove 42 is communicated with the second storage box 41;
a limiting cylinder 43; the limiting cylinder 43 is fixedly connected with the outer surface of the fixed bed body 1 and surrounds the feeding groove 42;
the packing auger 44 is rotatably connected in the limiting cylinder 43, and the packing auger 44 is driven by a motor;
when the device is used, firstly, the adsorbent is placed in the adsorption cavity 13 and the second storage box 41, then the controller controls the motor fixedly connected with the packing auger 44 to rotate, so as to control the packing auger 44 to rotate, in the rotating process of the packing auger 44, new adsorbent in the second storage box 41 can be pushed into the limiting cylinder 43, then the new adsorbent enters the feeding cavity 15 through the feeding groove 42, then the feed liquid is introduced into the adsorption cavity 13 through the feeding pipe, when the feed liquid passes through the adsorbent in the adsorption cavity 13, the adsorbent can adsorb and extract the feed liquid, the adsorbed feed liquid flows out of the adsorption cavity 13 through the liquid outlet pipe 12, when the adsorbed feed liquid passes through the detector, the detector can detect the change of the concentration of solute in the outflow feed liquid, so that the saturation condition of the adsorbent can be detected through the change of the concentration, when the adsorbent is saturated, the controller controls the first motor 23 to rotate anticlockwise, the rotating rod 21 can be driven to rotate in the rotating process of the first motor 23, the baffle plate 22 can be driven to rotate in the rotating process of the rotating rod 21, the adsorbent saturated in the adsorption saturation process can be transferred into the blanking cavity 14 in the rotating process of the baffle plate 22, the blanking cavity 14 is communicated with the first storage box 31 through the blanking groove 32, at the moment, the adsorbent saturated in the blanking cavity 14 can fall into the first storage box 31 to be collected, meanwhile, in the rotating process of the baffle plate 22, new adsorbent pushed into the feeding cavity 15 through the packing auger 44 can be transferred into the adsorption cavity 13 to be adsorbed, automatic material changing can be carried out in the process under the condition of not stopping adsorption, manual material changing when adsorption is required to be stopped can be avoided, and then the controller controls the packing auger 44 to continue to work to push new adsorbent into the feeding cavity 15, so that the next use is facilitated.
As an embodiment of the invention, two adjacent sides of each baffle 22 are fixedly connected with uniformly arranged filter plates 24, and the filter plates 24 are designed to be inclined upwards towards one side of the outer surface of the fixed bed body 1;
during operation, because baffle 22 both sides are equipped with the filter plate 24 of tilt up, after the feed liquid passes through feed liquor pipe 11 and gets into in the absorption chamber 13, the feed liquid can fall on filter plate 24, because filter plate 24 slopes, thereby can make the feed liquid flow on filter plate 24, speed when this in-process can reduce the feed liquid whereabouts, can increase the contact of feed liquid and adsorbent for a long time, thereby improve the adsorption effect of adsorbent to the feed liquid, a plurality of filter plates 24 can also make the adsorbent layering simultaneously, prevent that the adsorbent from piling up the mobility that influences the feed liquid on a large scale.
As an embodiment of the present invention, uniformly arranged feeding troughs 42 are opened in the feeding cavity 15 and the inner wall of the fixed bed body 1, and the lowest point of each feeding trough 42 is flush with the highest point of the corresponding filter plate 24;
during operation, because the material loading grooves 42 which are uniformly arranged are all level with the highest point of the filter plate 24, when the packing auger 44 rotates, new adsorbent can be pushed onto the filter plate 24 through the material loading grooves 42, and therefore the situation that the adsorbent cannot be prevented on a plurality of filter plates 24 is avoided.
As an embodiment of the present invention, two rotating shafts 25 are rotatably connected to the inner wall of each filter plate 24 by two motors; the same filter screen 26 is wound on the two rotating shafts 25;
in operation, because there is filter screen 26 through the winding of pivot 25 in the filter plate 24, at the in-process of adsorbent absorption feed liquid, the motor that bull stick 21 one side was kept away from in the controller control rotates, can drive filter screen 26 and remove and twine filter screen 26 at motor pivoted in-process, can make the adsorbent take place to remove even roll at this in-process, thereby can make the adsorbent trade the face and adsorb, thereby make the adsorbent adsorb comprehensively, improve adsorption effect, can also prevent simultaneously that the adsorbent from piling up the removal effect that influences the feed liquid, simultaneously when needing to carry out the unloading to the adsorbent that adsorbs the saturation, the motor that rotates and keeps away from bull stick 21 one side at this moment can drive filter screen 26 and remove, can take out filter plate 24 with the adsorbent at the in-process that filter screen 26 removed, prevent that the adsorbent from remaining on the filter plate 24, influence the material loading.
As an embodiment of the invention, uniformly arranged pricker needles 27 are fixedly connected to the rotating shaft 25 wound by each filter screen 26;
in operation, because the uniformly arranged needles 27 are fixedly connected to the rotating shafts 25 wound by the filter screen 26, the needles 27 can penetrate through the meshes of the filter screen 26 during the rotation of the rotating shafts 25, and the filter screen 26 can be prevented from being blocked to influence the flow of the feed liquid during the rotation.
As an embodiment of the present invention, the outer surface of the filter screen 26 is fixedly connected with uniformly arranged parting strips 28;
during operation, because filter screen 26 surface links firmly the parting bead 28 of evenly arranging, the in-process parting bead 28 that removes at filter screen 26 can promote the adsorbent and remove to increase adsorbent moving range, and then make that the adsorbent is comprehensive adsorbs the feed liquid, when carrying out the unloading to the adsorbent on filter plate 24, parting bead 28 can be more convenient push into first storage box 31 with the adsorbent.
As an embodiment of the present invention, each of the filter plates 24 has two sides higher than the middle bottom;
in operation, due to the high middle bottom of the two sides of the filter plate 24, when the adsorbent in the middle of the filter plate 24 is pushed out during the rotation of the filter screen 26, the adsorbent at the high sides of the filter plate 24 will slide down to the middle of the filter plate 24 and then be pushed out through the filter screen 26.
The specific working process is as follows:
when the invention is used, firstly, the adsorbent is placed in the adsorption cavity 13 and the second storage box 41, then the controller controls the motor fixedly connected with the packing auger 44 to rotate, thereby controlling the packing auger 44 to rotate, in the rotating process of the packing auger 44, the new adsorbent in the second storage box 41 can be pushed into the limiting cylinder 43, then the new adsorbent enters the feeding cavity 15 through the feeding groove 42, then the feed liquid is introduced into the adsorption cavity 13 through the feeding pipe, when the feed liquid passes through the adsorbent in the adsorption cavity 13, the adsorbent can adsorb and extract the feed liquid, the adsorbed feed liquid flows out of the adsorption cavity 13 through the liquid outlet pipe 12, when the adsorbed feed liquid passes through the detector, the detector can detect the change of the concentration of solute in the outflow feed liquid, thereby the saturation condition of the adsorbent can be detected through the change of the concentration, when the adsorbent is saturated, the controller controls the first motor 23 to rotate anticlockwise, the rotating rod 21 can be driven to rotate in the rotating process of the first motor 23, the baffle plate 22 can be driven to rotate in the rotating process of the rotating rod 21, the adsorbent saturated in the adsorption saturation process can be transferred into the blanking cavity 14 in the rotating process of the baffle plate 22, the blanking cavity 14 is communicated with the first storage box 31 through the blanking groove 32, at the moment, the adsorbent saturated in the blanking cavity 14 can fall into the first storage box 31 to be collected, meanwhile, in the rotating process of the baffle plate 22, new adsorbent pushed into the feeding cavity 15 through the packing auger 44 can be transferred into the adsorption cavity 13 to be adsorbed, automatic material changing can be carried out in the process under the condition of not stopping adsorption, manual material changing when adsorption is required to be stopped can be avoided, and then the controller controls the packing auger 44 to continue to work to push new adsorbent into the feeding cavity 15, so that the next use is facilitated.
The foregoing embodiments illustrate and describe the principles, principal features and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (10)
1. A solid extraction device for western medicine medicament; the method is characterized in that: comprises that
A fixed bed body (1); the fixed bed body (1) comprises:
a liquid inlet pipe (11); the liquid inlet pipe (11) is fixedly connected to the upper surface of the fixed bed body (1), and the liquid inlet pipe (11) is used for introducing liquid to be adsorbed;
a liquid outlet pipe (12); the liquid outlet pipe (12) is fixedly connected to the lower surface of the fixed bed body (1), and the liquid outlet pipe (12) is used for guiding the adsorbed liquid;
a detector; the detector is arranged on the liquid outlet pipe (12) and is used for detecting the change of the concentration of the solute in the feed liquid;
a refueling unit (2); the material changing unit (2) is arranged in the fixed bed body (1), and the fixed bed body (1) is divided into an adsorption cavity (13), a discharging cavity (14) and a feeding cavity (15) by the material changing unit (2); the liquid inlet pipe (11) and the liquid outlet pipe (12) are both communicated with the adsorption cavity (13);
an adsorbent; the adsorbent is one of active carbon or ion exchange resin, is placed in the adsorption cavity (13) and is used for substances in the feed liquid;
a blanking unit (3); the blanking unit (3) is arranged on the outer surface of the fixed bed body (1) and is communicated with the blanking cavity (14), and the blanking unit (3) is used for unloading the adsorbent saturated in adsorption;
a feeding unit (4); the feeding unit (4) is arranged on the outer surface of the fixed bed body (1) and is communicated with the feeding cavity (15), and the feeding unit (4) is used for placing unused adsorbent;
a controller; the controller is used for controlling the material changing unit (2), the blanking unit (3) and the feeding unit (4).
2. The solid-state extraction device of western medicine medicament according to claim 1, wherein: the refueling unit (2) comprises:
a rotating rod (21); the rotating rod (21) is rotatably connected to the central point of the fixed bed body (1);
a baffle (22); the number of the baffle plates (22) is three, and the baffle plates are fixedly connected with the outer surface of the rotating rod (21); one side of the rotating rod (21) far away from the rotating rod (21) is attached to the inner wall of the fixed bed body (1);
a first motor (23); the first motor (23) is fixedly connected to the lower surface of the fixed bed body (1), and the rotating rod (21) is fixedly connected with a rotating shaft of the first motor (23) through a coupling.
3. The solid-state extraction device of western medicine medicament according to claim 1, wherein: the blanking unit (3) comprises:
a first storage box (31); the first storage box (31) is fixedly connected with the outer surface of the fixed bed body (1), and a box cover is arranged at the top of the first storage box (31); the first storage box (31) corresponds to the blanking cavity (14);
a discharge chute (32); a blanking groove (32) is formed in the inner wall of the fixed bed body (1) in the blanking cavity (14), and the blanking groove (32) is communicated with the first storage box (31).
4. The solid-state extraction device of western medicine medicament according to claim 1, wherein: the feeding unit (4) comprises:
a second storage box (41); the second storage tank (41) is fixedly connected with the outer surface of the fixed bed body (1), and unused adsorbent is placed in the second storage tank (41); a box cover is arranged at the top of the second storage box (41); the second storage box (41) corresponds to the feeding cavity (15);
a feeding chute (42); a feeding groove (42) is formed in the inner wall of the fixed bed body (1) in the feeding cavity (15), and the feeding groove (42) is communicated with the second storage box (41);
a limiting cylinder (43); the limiting cylinder (43) is fixedly connected with the outer surface of the fixed bed body (1) and surrounds the feeding groove (42);
the packing auger (44) is rotatably connected in the limiting cylinder (43), and the packing auger (44) is driven by a motor.
5. The solid-state extraction device of western medicine medicament according to claim 2, wherein: every two liang adjacent one sides of baffle (22) all link firmly filter plate (24) of evenly arranging jointly, and filter plate (24) are for the design of upwards inclining to fixed bed body (1) surface one side.
6. The solid-state extraction device of western medicine medicament according to claim 4, wherein: the material loading cavity (15) and the inner wall of the fixed bed body (1) are provided with material loading grooves (42) which are uniformly distributed, and the lowest point of each material loading groove (42) is flush with the highest point of the corresponding filter plate (24).
7. The solid-state extraction device of western medicine medicament according to claim 5, wherein: two rotating shafts (25) are rotatably connected in the inner wall of each filter plate (24) through two motors; and the same filter screen (26) is wound on the two rotating shafts (25).
8. The solid-state extraction device of western medicine medicament according to claim 5, wherein: uniformly arranged pricker needles (27) are fixedly connected on a rotating shaft (25) wound by each filter screen (26).
9. The solid-state extraction device of western medicine medicament according to claim 7, wherein: the outer surface of the filter screen (26) is fixedly connected with partition bars (28) which are uniformly arranged.
10. The solid-state extraction device of western medicine medicament according to claim 1, wherein: the two sides of each filter plate (24) are higher than the middle bottom.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210075067.6A CN114225474B (en) | 2022-01-22 | 2022-01-22 | Solid-state extraction element of western medicine medicament |
Applications Claiming Priority (1)
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| JPH10286426A (en) * | 1997-04-15 | 1998-10-27 | Kuraray Eng Kk | Continuous adsorption device and utilizing method of the same |
| CN208413303U (en) * | 2018-04-08 | 2019-01-22 | 中冶长天国际工程有限责任公司 | For activated carbon adsorber or the rotary valve of Analytic Tower |
| CN112520252A (en) * | 2020-11-28 | 2021-03-19 | 江苏威拉里新材料科技有限公司 | Environment-controllable storage equipment for metal powder storage and storage process |
| CN113750733A (en) * | 2020-06-04 | 2021-12-07 | 湖南中冶长天节能环保技术有限公司 | Active carbon rotary blanking valve capable of preventing flue gas leakage and active blanking system |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10286426A (en) * | 1997-04-15 | 1998-10-27 | Kuraray Eng Kk | Continuous adsorption device and utilizing method of the same |
| CN208413303U (en) * | 2018-04-08 | 2019-01-22 | 中冶长天国际工程有限责任公司 | For activated carbon adsorber or the rotary valve of Analytic Tower |
| CN113750733A (en) * | 2020-06-04 | 2021-12-07 | 湖南中冶长天节能环保技术有限公司 | Active carbon rotary blanking valve capable of preventing flue gas leakage and active blanking system |
| CN112520252A (en) * | 2020-11-28 | 2021-03-19 | 江苏威拉里新材料科技有限公司 | Environment-controllable storage equipment for metal powder storage and storage process |
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