CN114225236A - Radiotherapy guiding device, radiotherapy guiding method, electronic equipment and storage medium - Google Patents
Radiotherapy guiding device, radiotherapy guiding method, electronic equipment and storage medium Download PDFInfo
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- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
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Abstract
The invention provides a radiotherapy guiding device, a radiotherapy guiding method, electronic equipment and a storage medium, wherein the radiotherapy guiding device comprises: the image data acquisition module is used for acquiring historical radiotherapy image data of an object to be treated, wherein the historical radiotherapy image data comprises a plurality of radiotherapy sub-image data; a physiological motion time phase acquisition module for acquiring real-time physiological motion information of a to-be-treated object and determining a plurality of real-time physiological motion time phases of the real-time physiological motion information; the image data determining module is used for determining a historical physiological motion time phase corresponding to the real-time physiological motion time phase and determining radiotherapy sub-image data corresponding to the real-time physiological motion time phase according to the historical physiological motion time phase; a radiotherapy guide module for guiding a radiotherapy process based on radiotherapy sub-image data. The invention can guide the radiotherapy process by obtaining the real-time physiological motion time phase, thereby improving the efficiency and the accuracy of radiation guide; and the structure such as a mechanical arm is not required to be additionally arranged, so that the cost of the radiotherapy guiding method is reduced.
Description
Technical Field
The invention relates to the technical field of radiotherapy, in particular to a radiotherapy guiding device, a radiotherapy guiding method, electronic equipment and a storage medium.
Background
Radiotherapy is one of the main technical means for treating malignant tumors, and aims to irradiate an affected part (tumor) with radiation at a maximum concentration and to accurately irradiate the affected part with radiation such as X-rays and electron beams in radiotherapy in which the affected part is irradiated with radiation. However, the affected part may move in accordance with physiological movements (e.g., respiration, heartbeat, pulse, etc.) of the patient. For example, a tumor near the lung moves substantially due to respiration.
In order to realize accurate radiotherapy in the radiotherapy process, a pair of independent mechanical arms is arranged in the prior art to image and observe a patient in real time in the radiotherapy process so as to determine an affected part in the radiotherapy process.
The prior art has the following problems: the setting cost of arm is high, the structure is complicated, and operating personnel need along with going on of radiotherapy process, and the manual control arm removes, and the operation is complicated, leads to that the efficiency and the accuracy of radiotherapy guide are all lower.
Disclosure of Invention
In view of the above, there is a need to provide a radiotherapy guiding apparatus, a radiotherapy guiding method, an electronic device and a storage medium, which are used to solve the technical problems of high cost of radiotherapy guiding and low efficiency and accuracy of radiotherapy guiding in the prior art.
In one aspect, the present invention provides a radiotherapy guide apparatus,
the device comprises an image data acquisition module, a physiological motion time phase acquisition module, an image data determination module and a radiotherapy guide module;
the image data acquisition module is used for acquiring historical radiotherapy image data of an object to be treated, wherein the historical radiotherapy image data comprises a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological motion phases;
the physiological motion time phase acquisition module is used for acquiring real-time physiological motion information of the object to be treated and determining a plurality of real-time physiological motion time phases of the real-time physiological motion information;
the image data determining module is used for determining the historical physiological motion time phase corresponding to the real-time physiological motion time phase and determining the radiotherapy sub-image data corresponding to the real-time physiological motion time phase according to the historical physiological motion time phase;
the radiotherapy guiding module is used for guiding a radiotherapy process based on the radiotherapy sub-image data.
In some possible implementations, the radiation therapy guidance module is specifically configured to:
determining whether the radiation therapy session requires adjustment based on the radiotherapy sub-image data.
In some possible implementations, the radiotherapy guiding module includes a therapy radiation field acquiring submodule, a region of interest acquiring submodule, and an adjustment judging submodule;
the treatment radiation field acquisition sub-module is used for acquiring a treatment radiation field in a radiotherapy plan;
the region-of-interest acquisition sub-module is used for determining a correction region-of-interest in the radiotherapy sub-image data;
the adjustment judgment sub-module is used for determining whether the radiotherapy process needs to be adjusted according to the treatment radiation field and the correction region of interest.
In some possible implementations, the adjustment judgment submodule includes an overlap area obtaining unit and an adjustment judgment unit;
the overlapping area acquisition unit is used for acquiring the overlapping area of the overlapping part of the treatment radiation field and the correction region of interest;
the adjustment judging unit is used for judging whether the radiotherapy process needs to be adjusted according to the overlapping area.
In some possible implementations, the adjustment determining unit includes an area ratio determining subunit and a first adjusting subunit;
the area ratio judging subunit is configured to judge whether a ratio of the overlap area to a correction region of interest of the correction region of interest is greater than or equal to a first threshold;
the first adjusting subunit is configured to adjust the radiation therapy session when a ratio of the overlap area to the corrected region of interest area is smaller than the first threshold.
In some possible implementations, the region of interest acquisition sub-module includes an original region acquisition unit, a registration relationship acquisition unit, and a region correction unit;
the original region acquisition unit is used for acquiring an original region of interest of a planning image in a radiotherapy plan;
the registration relation acquisition unit is used for acquiring the registration relation between the original region of interest and the corrected region of interest;
the region correction unit is configured to determine the corrected region of interest based on the registration relationship and the original region of interest.
In some possible implementations, the radiotherapy guiding apparatus further comprises:
and the dynamic display module is used for dynamically displaying the radiotherapy sub-image data corresponding to each real-time physiological motion time phase according to the plurality of real-time physiological motion time phases.
In another aspect, the present invention provides a radiotherapy guiding method, including:
acquiring historical radiotherapy image data of an object to be treated, wherein the historical radiotherapy image data comprises a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological motion phases;
acquiring real-time physiological motion information of a to-be-treated object, and determining a plurality of real-time physiological motion time phases of the real-time physiological motion information;
determining the historical physiological motion time phase corresponding to the real-time physiological motion time phase, and determining the radiotherapy sub-image data corresponding to the real-time physiological motion time phase according to the historical physiological motion time phase;
guiding a radiotherapy procedure based on the radiotherapy sub-image data.
In another aspect, the present invention also provides an electronic device comprising a memory and a processor, wherein,
the memory is used for storing programs;
the processor, coupled to the memory, is configured to execute the program stored in the memory to implement the steps of the radiation therapy guidance method described in any of the above implementations.
In another aspect, the present invention further provides a computer-readable storage medium for storing a computer-readable program or instructions, which when executed by a processor can implement the steps of the radiation therapy guidance method described in any of the above-mentioned implementations.
The beneficial effects of adopting the above embodiment are: the radiotherapy guiding device provided by the invention acquires historical radiotherapy image data by arranging an image data acquisition module, wherein the historical radiotherapy image data comprises a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological motions; then, real-time physiological motion information is obtained through a physiological motion time phase obtaining module, and a plurality of real-time physiological motion time phases of the real-time physiological motion information are determined; and then the image data determining module determines radiotherapy sub-image data corresponding to the real-time physiological motion, and the radiotherapy guiding module guides the radiotherapy process based on the radiotherapy sub-image data. According to the invention, the affected part is not required to be imaged while the real-time physiological motion information is acquired, and the corresponding radiotherapy sub-image data can be determined by acquiring the real-time physiological motion time phase, so that the radiotherapy process is guided, and the efficiency and accuracy of radiation guidance are improved; moreover, radiotherapy sub-image data corresponding to the real-time physiological motion can be obtained only through the real-time physiological motion, and structures such as mechanical arms do not need to be additionally arranged, so that the cost of radiotherapy guide of the radiotherapy guide device is reduced.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.
FIG. 1 is a schematic structural diagram of one embodiment of a radiation therapy guiding apparatus provided by the present invention;
FIG. 2 is a schematic diagram of one embodiment of real-time respiratory information provided by the present invention;
FIG. 3 is a schematic structural diagram of an embodiment of a radiation therapy guidance module provided by the present invention;
FIG. 4 is a schematic structural diagram of an adjustment judgment sub-module according to an embodiment of the present invention;
FIG. 5 is a flowchart illustrating an embodiment of an adjustment determination unit according to the present invention;
FIG. 6 is a schematic flow chart illustrating another embodiment of an adjustment determination unit according to the present invention;
FIG. 7 is a flowchart illustrating an embodiment of a region-of-interest obtaining sub-module provided in the present invention;
FIG. 8 is a schematic structural diagram of another embodiment of a radiation treatment guiding apparatus provided by the present invention;
FIG. 9 is a flowchart illustrating a method for guiding radiation therapy according to an embodiment of the present invention;
fig. 10 is a schematic structural diagram of an embodiment of an electronic device provided in the present invention.
Detailed Description
The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the embodiments of the present invention, "a plurality" means two or more unless otherwise specified. "and/or" describes the association relationship of the associated objects, meaning that three relationships may exist, for example: a and/or B, may represent: a exists alone, A and B exist simultaneously, and B exists alone.
In embodiments of the present invention, the terms "radiation therapy," "radiotherapy," and "treatment" are used interchangeably to refer to treating a patient. The terms "subject to be treated", "patient", "treatment area", "tumor" are used interchangeably to refer to the subject and/or area of treatment. The terms "region," "location," and "treatment region" interchangeably refer to the location of the treatment region shown in the image or the actual location of the treatment region within or on the patient's body.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the invention. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.
The present invention provides a radiotherapy guiding apparatus, a radiotherapy guiding method, an electronic device and a storage medium, which are described below.
Fig. 1 is a schematic structural diagram of an embodiment of a radiotherapy guiding apparatus provided in the present invention, as shown in fig. 1, a radiotherapy guiding apparatus 10 includes an image data acquisition module 100, a physiological motion phase acquisition module 200, an image data determination module 300, and a radiotherapy guiding module 400;
the image data acquisition module 100 is configured to acquire historical radiotherapy image data of an object to be treated, where the historical radiotherapy image data includes a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological motions;
the physiological motion time phase acquisition module 200 is configured to acquire real-time physiological motion information of a subject to be treated, and determine a plurality of real-time physiological motion time phases of the real-time physiological motion information;
the image data determining module 300 is configured to determine a historical physiological motion time phase corresponding to the real-time physiological motion time phase, and determine radiotherapy sub-image data corresponding to the real-time physiological motion time phase according to the historical physiological motion time phase;
the radiation therapy guidance module 400 is used to guide the radiation therapy process based on the radiotherapy sub-image data.
It should be understood that: the historical radiotherapy image data in the image data acquisition module 100 is acquired before radiotherapy, and the real-time physiological motion information in the physiological motion phase acquisition module 200 is acquired during radiotherapy.
Compared with the prior art, the radiotherapy guiding device 10 provided by the embodiment of the invention acquires historical radiotherapy image data before radiotherapy through the image data acquisition module 100, wherein the historical radiotherapy image data comprises a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological motions; acquiring real-time physiological motion information in the radiotherapy process through a physiological motion time phase acquisition module 200, and determining a plurality of real-time physiological motion time phases of the real-time physiological motion information; radiotherapy sub-image data corresponding to the real-time physiological motion phase is then determined by the image data determination module 300 and the radiotherapy guidance module 400 guides the radiotherapy process based on the radiotherapy sub-image data. According to the embodiment of the invention, the affected part does not need to be imaged in the radiotherapy process, and the radiotherapy sub-image data corresponding to the affected part can be determined by obtaining the real-time physiological motion time phase, so that the radiotherapy process is guided, and the efficiency and the accuracy of radiation guidance are improved; moreover, the radiotherapy sub-image data corresponding to the real-time physiological motion can be obtained only through the real-time physiological motion, and structures such as mechanical arms do not need to be additionally arranged, so that the cost of the radiotherapy guiding device is reduced.
It should be noted that: the historical radiotherapy image data can be any one of four-dimensional image data, three-dimensional image data or two-dimensional images, and the radiotherapy sub-image data respectively corresponds to the three-dimensional image data, the two-dimensional image data or the one-dimensional image data. Namely: the historical radiotherapy image data comprises temporal information compared to the radiotherapy sub-image data.
In some embodiments of the present invention, the acquiring of the historical radiotherapy image data in the image data acquiring module 100 may specifically be: historical radiotherapy image data is acquired by an imaging device or an imaging device coupled with a treatment device. In particular, the imaging device may comprise a single modality scanning device or a multi-modality scanning device. The single modality scanning device may include, for example, a Positron Emission Tomography (PET) device, a Single Photon Emission Computed Tomography (SPECT) device, an ultrasound device, an X-ray device, a Computed Tomography (CT) device, a Magnetic Resonance Imaging (MRI) device, and the like, or any combination thereof. The multi-modality scanning device may include a positron emission tomography-computed tomography (PET-CT) scanning device, a positron emission tomography-magnetic resonance imaging (PET-MRI) scanning device, and the like.
In particular, the treatment device may be a medical accelerator, which may be any one of the medical accelerators of the prior art, such as: the description of the medical electron linear accelerator is omitted here.
Further, the image data acquiring module 100 is specifically configured to: the method comprises the steps of synchronously acquiring historical radiotherapy image data and historical physiological motion information before radiotherapy, determining a plurality of historical physiological motion time phases of the historical physiological motion information, and dividing the historical radiotherapy image data into a plurality of radiotherapy sub-image data corresponding to the plurality of historical physiological motion time phases based on the plurality of historical physiological motion time phases.
In some embodiments of the present invention, the historical physiological motion information and the real-time physiological motion information are presented in the form of a historical physiological motion waveform curve and a real-time physiological motion waveform curve, respectively.
In some embodiments of the present invention, the physiological motion phase may include, but is not limited to, a respiratory phase, a pulse phase, and a heartbeat phase.
In a specific embodiment of the invention, the physiological motion phase is a respiratory phase; the historical physiological motion phase in the image data acquiring module 100 and the real-time winning motion phase in the physiological motion phase acquiring module 200 are both respiratory phases, where the respiratory phases may include inspiratory phases and/or expiratory phases, and taking a real-time respiratory waveform curve as an example, as shown in fig. 2, an abscissa in fig. 2 is time, and an ordinate is respiratory amplitude, then the curve in fig. 2 is a real-time respiratory waveform curve, and in some embodiments of the present invention, a trough in the real-time respiratory waveform curve may correspond to an end of an expiratory phase, and a peak may correspond to an end of an inspiratory phase. Then, along the time sequence, the time phase from one wave trough to the adjacent wave trough is the inspiration time phase, and the time phase from one wave trough to the adjacent wave trough is the expiration time phase.
It should be understood that: in some embodiments, one inspiratory phase or one expiratory phase may correspond to one radiotherapeutic sub-image data. In other embodiments, one radiotherapeutic sub-image data may comprise at least two inspiratory phases or at least two expiratory phases. The radiotherapy sub-image data includes several inspiratory phases or respiratory phases, which can be adjusted according to actual conditions, and is not described herein.
In some embodiments of the present invention, the object to be treated in the image data acquisition module 100 and the object to be treated in the physiological motion phase acquisition module 200 may be biological or non-biological. For example, the object to be treated may be a human body, an animal body, an artificial object (e.g., a phantom), or the like. In particular, the object to be treated may comprise a specific part of the body, such as the head, the chest, the abdomen, etc. or any combination thereof. In addition, the object to be treated may also include specific organs such as heart, esophagus, trachea, bronchi, stomach, gall bladder, small intestine, colon, bladder, ureter, uterus, fallopian tube, etc.
In some embodiments of the present invention, acquiring historical radiotherapy image data prior to radiation treatment may refer to a short time before radiation treatment is performed (e.g., 1 minute, 3 minutes, 5 minutes, etc. before radiation treatment is performed); it is also intended that the radiation treatment be preceded by a longer period of time (e.g., 1 day, 3 days, 5 days, etc.) before the radiation treatment is administered. When the specific radiation image data is obtained, the adjustment can be performed according to the actual situation, which is not described herein.
In some embodiments of the present invention, the real-time respiratory information in the physiological motion phase acquisition module 200 is acquired in a manner including, but not limited to: the respiratory waveform curve is acquired by contact type respiratory waveform curve acquisition equipment or non-contact type respiratory waveform curve acquisition equipment.
In some embodiments of the invention, the radiation therapy guidance module 400 is specifically configured to:
it is determined whether the radiation therapy session needs to be adjusted based on the radiotherapy sub-image data.
According to the embodiment of the invention, whether the radiotherapy process needs to be adjusted or not is determined according to the radiotherapy sub-image data, so that the object to be treated can be protected while the radiotherapy is carried out on the object to be treated.
In some embodiments of the invention, making adjustments to the radiation therapy process includes, but is not limited to: interrupting the radiation therapy session or making adjustments to the radiation therapy plan.
Specifically, the method comprises the following steps: the adjusting of the radiation therapy plan may be adjusting a treatment field in the radiation therapy plan.
In some embodiments of the present invention, as shown in fig. 3, the radiation therapy guidance module 400 includes a therapy field acquisition sub-module 410, a region of interest acquisition sub-module 420, and an adjustment determination sub-module 430;
the treatment radiation field acquisition sub-module 410 is used for acquiring a treatment radiation field in the radiation treatment plan;
the region of interest acquisition sub-module 420 is configured to determine a corrected region of interest in the radiotherapy sub-image data;
the adjustment decision sub-module 430 is used to determine whether the radiation treatment process needs to be adjusted based on the treatment field and the corrected region of interest.
Whether the radiotherapy process needs to be adjusted or not is determined according to the treatment setting and the correction interested area, so that the radiation beam can be irradiated into the correction interested area, the radiation beam is prevented from being irradiated into other areas except the correction interested area, the influence on normal tissues and organs of the object to be treated is avoided, and the reliability and the safety of the radiotherapy device are further improved.
It should be understood that: the radiation therapy plan in the therapy radiation field acquisition sub-module 410 refers to a therapy plan which is made according to the shape and the position of the tumor in the patient determined in advance before the tumor in the patient is treated, that is, the therapy radiation field in the radiation therapy device, the dose rate received by each position of the tumor, the position of a gantry in the radiation therapy device, and the like are determined.
In some embodiments of the present invention, the treatment field in the treatment field acquisition sub-module 410 is the irradiation range of the radiation beam after passing through the conformal/collimator, and the shape of the treatment field can be any one of a square, a rectangle, a circle or an irregular figure.
It should be noted that: the corrected region of interest in the region of interest acquisition sub-module 420 is delineated based on the isocenter, which is the center of the treatment field. Wherein, the isocenter refers to a point where the rotation axes of the frame, the radiation head and the treatment couch of the medical electron linear accelerator intersect.
It should also be noted that: in some embodiments of the invention, the radiation therapy guidance module 400 is further configured to:
a radiation dose of the radiation beam within the corrected region of interest in the radiation therapy sub-image data is determined, and the radiation therapy session is adjusted when the radiation dose is greater than a threshold dose.
Whether the radiotherapy process is adjusted or not is judged according to the radiation dose, so that the damage to the object to be treated caused by the fact that the excessive ray beams irradiate the object to be treated can be avoided, and the safety and the reliability of the radiotherapy process are further improved.
In some embodiments of the present invention, as shown in fig. 4, the adjustment judgment sub-module 430 includes an overlap area obtaining unit 431 and an adjustment judgment unit 432;
an overlap area acquisition unit 431 for acquiring an overlap area of the treatment field and the overlapping portion of the correction region of interest;
the adjustment judging unit 432 is used for judging whether the radiotherapy process needs to be adjusted according to the overlapping area.
Specifically, in some embodiments of the present invention, as shown in fig. 5, the adjustment determining unit 432 includes an area determining subunit 4321 and a second adjusting subunit 4322;
the area judgment subunit 4321 is configured to judge whether the overlapping area is greater than or equal to an area threshold;
the second adjusting subunit 4322 is configured to adjust the radiation therapy session when the overlapping area is smaller than the area threshold.
Since the therapeutic field is the irradiation range of the radiation beam after passing through the conformal/collimator, namely: the therapeutic radiation field is the irradiation range of the radiation beam on the human body after passing through the conformal/collimator, if the overlapping area is smaller than the area threshold value, part of the correction interested area can be missed for irradiation, and the radiation beam can possibly irradiate normal tissues and organs except the correction interested area, therefore, when the overlapping area is smaller than the area threshold value, the radiation therapy process is adjusted, and the safety and the reliability of the radiation therapy process can be improved.
Further, since the area threshold is a constant value in general and the area of the region of interest is corrected differently in different cases, which may result in inaccurate adjustment for determining whether the radiotherapy process needs to be adjusted by the area threshold, in some embodiments of the present invention, as shown in fig. 6, the adjustment determining unit 432 includes an area ratio determining subunit 4323 and a first adjusting subunit 4324:
the area ratio judging subunit 4323 is configured to judge whether a ratio of the overlapping area to a corrected region of interest of the corrected region of interest is greater than a first threshold;
the first adjusting subunit 4324 is configured to adjust the radiation therapy treatment process if the ratio of the overlapping area to the corrected region of interest is smaller than a first threshold.
Whether the radiotherapy process needs to be adjusted or not is judged based on the ratio of the overlapped area to the area of the correction region of interest, and compared with the method for judging whether the radiotherapy process needs to be adjusted or not through an area threshold value, the judgment result is not affected by different correction region of interest areas of different cases, so that the judgment is more reliable and accurate.
The difference between the original planning image and the radiotherapy image may occur due to the difference in the positioning of the object to be treated or the change in the organ/lesion area of the object to be treated itself. Therefore, in some embodiments of the present invention, as shown in fig. 7, the region of interest acquisition sub-module 420 includes an original region acquisition unit 421, a registration relation acquisition unit 422, and a region correction unit 423;
the original region acquisition unit 421 is used for acquiring an original region of interest of a planning image in a radiation treatment plan;
the registration relation obtaining unit 422 is configured to obtain a registration relation between the original region of interest and the corrected region of interest;
the region correction unit 423 is configured to determine a corrected region of interest based on the registration relationship and the original region of interest.
It should be understood that: the radiation treatment plan in the original region acquisition unit 421 may be a radiation treatment plan determined through expert consultation before radiation treatment.
The registration relationship in the registration relationship acquisition unit 422 refers to considering the correspondence between the change of the region of interest caused by the physiological motion of the object to be treated and the original region of interest.
Wherein the registration relationship comprises a rigid registration relationship and a non-rigid registration relationship. The rigid registration relation comprises a translation relation and a rotation transformation relation, and the non-rigid registration relation comprises a projective relation, an elastic transformation relation and the like.
The embodiment of the invention obtains the corrected interested area of the radiotherapy sub-image data by registering the original interested area, avoids the change of the interested area caused by the positioning difference of the object to be treated or the change of the organ/focus area of the object to be treated, and can further improve the accuracy of radiotherapy.
To enable adjustments to the radiation therapy session, in some embodiments of the present invention, the radiation therapy guidance module 400 in the radiation therapy guidance device 10 is further configured to:
when the radiation therapy process needs to be adjusted, the radiation therapy plan is adjusted in response to the adjustment instruction.
According to the embodiment of the invention, when the radiotherapy process needs to be adjusted, the adjustment instruction is responded, and the radiotherapy plan is adjusted based on the adjustment instruction, so that the controllability of adjusting the radiotherapy plan can be realized.
It should be noted that: adjusting the radiation treatment plan includes, but is not limited to, adjusting a treatment field, a radiation dose, in the radiation treatment plan, wherein adjusting the treatment field includes, but is not limited to, adjusting a treatment field shape. The adjustment of the treatment field shape can be made by adjusting relevant parameters in the radiation treatment plan, such as: adjusting the position of the leaves in the conformal/collimator.
It should be understood that: the adjustment instruction may be generated by the doctor when the treatment radiation field needs to be adjusted, or may be automatically generated when the treatment radiation field needs to be adjusted, and the adjustment instruction is specifically generated by what manner, and can be adjusted according to actual needs, which is not described herein again.
It should be noted that: if the adjusting instruction is generated by the doctor when the treatment radiation field needs to be adjusted, an interactive interface needs to be provided, and the doctor generates the adjusting instruction by clicking the interactive interface.
The embodiment of the invention generates the adjusting instruction by providing two different modes, adjusts the treatment radiation field and can improve the redundancy and diversity of the adjustment of the treatment radiation field.
In order to facilitate the operator to visually see the radiotherapy subimage data at the current real-time physiological motion phase, in some embodiments of the present invention, as shown in fig. 8, the radiotherapy guiding apparatus 10 further includes a dynamic display module 500;
the dynamic display module 500 is configured to dynamically display radiotherapy sub-image data corresponding to each real-time physiological motion time phase according to a plurality of real-time physiological motion time phases.
The radiotherapy sub-image data corresponding to each real-time physiological motion time phase is dynamically displayed according to the plurality of real-time physiological motion time phases, so that an operator can visually see the radiotherapy sub-image data under the current real-time physiological motion time phase in the radiotherapy process.
In some embodiments of the invention, the plurality of real-time physiological motion phases comprises a first real-time physiological motion phase and a second real-time physiological motion phase, and the plurality of radiotherapy sub-image data comprises first radiotherapy sub-image data corresponding to the first real-time physiological motion phase and second radiotherapy sub-image data corresponding to the second real-time physiological motion phase; the dynamic presentation module 500 is specifically configured to:
when the real-time physiological motion time phase is a first real-time physiological motion time phase, displaying first radiotherapy sub-image data;
and when the real-time physiological motion phase is a second real-time physiological motion phase, displaying second radiotherapy sub-image data.
Namely: along with the switching of the real-time physiological motion time phase, radiotherapy sub-image data corresponding to the real-time physiological motion time phase is displayed, so that the dynamic display of the radiotherapy sub-image data can be realized.
In order to better implement the radiotherapy guiding apparatus in the embodiment of the present invention, on the basis of the radiotherapy guiding apparatus, correspondingly, as shown in fig. 9, the embodiment of the present invention further provides a radiotherapy guiding method, where the radiotherapy guiding method includes:
s901, acquiring historical radiotherapy image data of an object to be treated, wherein the historical radiotherapy image data comprises a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological motion phases;
s902, acquiring real-time physiological motion information of an object to be treated, and determining a plurality of real-time physiological motion time phases of the real-time physiological motion information;
s903, determining a historical physiological motion time phase corresponding to the real-time physiological motion time phase, and determining radiotherapy sub-image data corresponding to the real-time physiological motion time phase according to the historical physiological motion time phase;
and S904, guiding the radiotherapy process based on the radiotherapy sub-image data.
The radiation therapy guiding method provided by the above embodiment can implement the technical solutions described in the above embodiments of the radiation therapy guiding apparatus, and the specific implementation principles of the modules or units can refer to the corresponding contents in the above embodiments of the radiation therapy guiding apparatus, and are not described herein again.
As shown in fig. 10, the present invention further provides an electronic device 1000 accordingly. The electronic device 1000 includes a processor 1001, a memory 1002, and a display 1003. Fig. 10 shows only some of the components of the electronic device 1000, but it is to be understood that not all of the shown components are required to be implemented, and that more or fewer components may be implemented instead.
The storage 1002 may be an internal storage unit of the electronic device 1000 in some embodiments, such as a hard disk or a memory of the electronic device 1000. The memory 1002 may also be an external storage device of the electronic device 1000 in other embodiments, such as a plug-in hard disk, a Smart Media Card (SMC), a Secure Digital (SD) Card, a Flash memory Card (Flash Card), and the like, provided on the electronic device 1000.
Further, the memory 1002 may also include both internal storage units and external storage devices of the electronic device 1000. The memory 1002 is used for storing application software and various data for installing the electronic device 1000.
The processor 1001 may be, in some embodiments, a Central Processing Unit (CPU), microprocessor or other data Processing chip for executing program codes stored in the memory 1002 or Processing data, such as the radiation therapy guidance method of the present invention.
The display 1003 may be an LED display, a liquid crystal display, a touch-sensitive liquid crystal display, an OLED (Organic Light-Emitting Diode) touch panel, or the like in some embodiments. The display 1003 is used to display information at the electronic device 1000 and to display a visual user interface. The components 1001 and 1003 of the electronic device 1000 communicate with each other via a system bus.
In one embodiment, when the processor 1001 executes the radiation treatment guidance program in the memory 1002, the following steps may be implemented:
acquiring historical radiotherapy image data of an object to be treated, wherein the historical radiotherapy image data comprises a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological motion phases;
acquiring real-time physiological motion information of an object to be treated, and determining a plurality of real-time physiological motion time phases of the real-time physiological motion information;
determining a historical physiological motion time phase corresponding to the real-time physiological motion time phase, and determining radiotherapy sub-image data corresponding to the real-time physiological motion time phase according to the historical physiological motion time phase;
the radiation therapy process is guided based on the radiotherapy sub-image data.
It should be understood that: the processor 1001, when executing the radiation therapy guidance program in the memory 1002, may also perform other functions in addition to the above functions, which may be specifically described with reference to the foregoing description of the corresponding method embodiments.
Further, the type of the electronic device 1000 is not particularly limited in the embodiment of the present invention, and the electronic device 1000 may be a portable electronic device such as a mobile phone, a tablet computer, a Personal Digital Assistant (PDA), a wearable device, and a laptop computer (laptop). Exemplary embodiments of portable electronic devices include, but are not limited to, portable electronic devices that carry an IOS, android, microsoft, or other operating system. The portable electronic device may also be other portable electronic devices such as laptop computers (laptop) with touch sensitive surfaces (e.g., touch panels), etc. It should also be understood that in other embodiments of the present invention, the electronic device 1000 may not be a portable electronic device, but may be a desktop computer having a touch-sensitive surface (e.g., a touch panel).
Accordingly, the present application also provides a computer-readable storage medium for storing a computer-readable program or instruction, which when executed by a processor can implement the steps or functions of the radiation therapy guidance method provided by the above-mentioned method embodiments.
According to the radiotherapy guiding device, the radiotherapy guiding method, the electronic device and the storage medium provided by the embodiment of the invention, historical radiotherapy image data is acquired before radiotherapy, and the historical radiotherapy image data comprises a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological motion phases; acquiring real-time physiological motion information in the radiotherapy process, and determining a plurality of real-time physiological motion time phases of the real-time physiological motion information; and then determining radiotherapy sub-image data corresponding to the real-time physiological motion phase, and guiding a radiotherapy process based on the radiotherapy sub-image data. The affected part does not need to be imaged in the radiation treatment process, the corresponding radiation treatment sub-image data can be determined by obtaining the real-time physiological motion time phase, the radiation treatment process is guided, and the efficiency and the accuracy of radiation guide are improved. Moreover, radiotherapy sub-image data corresponding to the real-time physiological motion can be obtained only through the real-time physiological motion, and structures such as mechanical arms do not need to be additionally arranged, so that the cost of the radiotherapy guiding method is reduced.
Those skilled in the art will appreciate that all or part of the flow of the method implementing the above embodiments may be implemented by instructing relevant hardware (such as a processor, a controller, etc.) by a computer program, and the computer program may be stored in a computer readable storage medium. The computer readable storage medium is a magnetic disk, an optical disk, a read-only memory or a random access memory.
The radiotherapy guiding apparatus, the radiotherapy guiding method, the electronic device and the storage medium provided by the present invention are described in detail above, and the principle and the embodiment of the present invention are explained in the present document by applying specific examples, and the description of the above embodiments is only used to help understanding the method and the core idea of the present invention; meanwhile, for those skilled in the art, according to the idea of the present invention, there may be variations in the specific embodiments and the application scope, and in summary, the content of the present specification should not be construed as a limitation to the present invention.
Claims (10)
1. A radiotherapy guiding device is characterized by comprising an image data acquisition module, a physiological motion time phase acquisition module, an image data determination module and a radiotherapy guiding module;
the image data acquisition module is used for acquiring historical radiotherapy image data of an object to be treated, wherein the historical radiotherapy image data comprises a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological motion phases;
the physiological motion time phase acquisition module is used for acquiring real-time physiological motion information of the object to be treated and determining a plurality of real-time physiological motion time phases of the real-time physiological motion information;
the image data determining module is used for determining the historical physiological motion time phase corresponding to the real-time physiological motion time phase and determining the radiotherapy sub-image data corresponding to the real-time physiological motion time phase according to the historical physiological motion time phase;
the radiotherapy guiding module is used for guiding a radiotherapy process based on the radiotherapy sub-image data.
2. The radiation therapy guidance device of claim 1, wherein the radiation therapy guidance module is specifically configured to:
determining whether the radiation therapy session requires adjustment based on the radiotherapy sub-image data.
3. The radiotherapy guiding apparatus of claim 2, wherein the radiotherapy guiding module comprises a treatment radiation field acquisition sub-module, a region of interest acquisition sub-module, and an adjustment judgment sub-module;
the treatment radiation field acquisition sub-module is used for acquiring a treatment radiation field in a radiotherapy plan;
the region-of-interest acquisition sub-module is used for determining a correction region-of-interest in the radiotherapy sub-image data;
the adjustment judgment sub-module is used for determining whether the radiotherapy process needs to be adjusted according to the treatment radiation field and the correction region of interest.
4. The radiotherapy guiding apparatus according to claim 3, wherein the adjustment judgment submodule includes an overlap area acquisition unit and an adjustment judgment unit;
the overlapping area acquisition unit is used for acquiring the overlapping area of the overlapping part of the treatment radiation field and the correction region of interest;
the adjustment judging unit is used for judging whether the radiotherapy process needs to be adjusted according to the overlapping area.
5. The radiotherapy guiding apparatus of claim 4, wherein the adjustment judging unit comprises an area ratio judging subunit and a first adjusting subunit;
the area ratio judging subunit is configured to judge whether a ratio of the overlap area to a correction region of interest of the correction region of interest is greater than or equal to a first threshold;
the first adjusting subunit is configured to adjust the radiation therapy session when a ratio of the overlap area to the corrected region of interest area is smaller than the first threshold.
6. The radiotherapy guiding apparatus of claim 3, wherein the region of interest acquisition sub-module comprises a raw region acquisition unit, a registration relation acquisition unit, and a region correction unit;
the original region acquisition unit is used for acquiring an original region of interest of a planning image in a radiotherapy plan;
the registration relation acquisition unit is used for acquiring the registration relation between the original region of interest and the corrected region of interest;
the region correction unit is configured to determine the corrected region of interest based on the registration relationship and the original region of interest.
7. The radiation treatment guidance device of claim 1, further comprising a dynamic presentation module;
the dynamic display module is used for dynamically displaying the radiotherapy sub-image data corresponding to each real-time physiological motion time phase according to the plurality of real-time physiological motion time phases.
8. A radiation therapy guidance method, comprising:
acquiring historical radiotherapy image data of an object to be treated, wherein the historical radiotherapy image data comprises a plurality of radiotherapy sub-image data corresponding to a plurality of historical physiological motion phases;
acquiring real-time physiological motion information of a to-be-treated object, and determining a plurality of real-time physiological motion time phases of the real-time physiological motion information;
determining the historical physiological motion time phase corresponding to the real-time physiological motion time phase, and determining the radiotherapy sub-image data corresponding to the real-time physiological motion time phase according to the historical physiological motion time phase;
guiding a radiotherapy procedure based on the radiotherapy sub-image data.
9. An electronic device comprising a memory and a processor, wherein,
the memory is used for storing programs;
the processor, coupled to the memory, is configured to execute the program stored in the memory to implement the steps of the radiation therapy guidance method of claim 8.
10. A computer-readable storage medium storing a computer-readable program or instructions, which when executed by a processor, is capable of implementing the steps of the radiation therapy guidance method of claim 8.
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