CN114200369A - Magnetic resonance imaging system and method integrating nerve regulation and control and radio frequency coil - Google Patents
Magnetic resonance imaging system and method integrating nerve regulation and control and radio frequency coil Download PDFInfo
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- CN114200369A CN114200369A CN202111547457.0A CN202111547457A CN114200369A CN 114200369 A CN114200369 A CN 114200369A CN 202111547457 A CN202111547457 A CN 202111547457A CN 114200369 A CN114200369 A CN 114200369A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
- A61B5/004—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
- G01R33/34—Constructional details, e.g. resonators, specially adapted to MR
- G01R33/34084—Constructional details, e.g. resonators, specially adapted to MR implantable coils or coils being geometrically adaptable to the sample, e.g. flexible coils or coils comprising mutually movable parts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2576/00—Medical imaging apparatus involving image processing or analysis
- A61B2576/02—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/30—Assessment of water resources
Abstract
The invention discloses a magnetic resonance imaging system and method integrating nerve regulation and control and a head magnetic resonance radio frequency coil, which are used for carrying out magnetic resonance imaging by combining other related brain function intervention regulation and control means on the basis of the traditional functional magnetic resonance imaging. The system comprises: a frame having a first stimulation device mounting area and a second device mounting area; a head magnetic resonance radio frequency coil comprising a flexible wearable base and a radio frequency coil disposed in the flexible wearable base, the head magnetic resonance radio frequency coil having a first channel and a second channel; the stimulation device comprises a first stimulation device and a second stimulation device, the first stimulation device and the second stimulation device are installed in the first device installation area and the second device installation area simultaneously or in a time-sharing mode respectively, the first stimulation device is an electromagnetic stimulation device and acts on a testee through the first channel, and the second stimulation device is a visual stimulation device and acts on the testee through the second channel.
Description
Technical Field
Embodiments of the present application relate to magnetic resonance imaging systems, methods and head magnetic resonance radio frequency coils for integrated neuromodulation.
Background
Conventional functional magnetic resonance imaging (fMRI) used in the field of clinical imaging examination is task-wise imaging with visual stimuli (allowing the subject to look at some cognitive or emotional picture at some point in time). fMRI is greatly limited by whether the subject is or has been looking at the test picture, and therefore the results are highly subjective. On the other hand, in the field of treating mental diseases by means of nerve regulation, physical fields (such as magnetic fields, currents, ultrasound and the like) generated by electromagnetic equipment act on the brain to perform brain function intervention regulation, but the methods belong to positioning treatment, namely, the brain target point acted by the physical fields is predetermined. However, the human brain function partitions are greatly different from individual to individual, and the brain function intervention and control means is difficult to realize individual precise medical treatment.
Disclosure of Invention
The embodiment of the application aims to provide a magnetic resonance imaging system and method integrating nerve regulation and control and a head magnetic resonance radio frequency coil, so that the magnetic resonance imaging system and method can be used for carrying out magnetic resonance imaging on the basis of traditional functional magnetic resonance imaging in combination with other related brain functional intervention regulation and control means. Therefore, the limitation of the traditional functional magnetic resonance imaging in the aspect of visual stimulation can be broken through, and meanwhile, the related brain function intervention regulation and control means can be changed from a passive positioning treatment means to a functional magnetic resonance imaging stimulation means, so that individualized functional targets can be defined, and further individualized accurate medical treatment on mental diseases can be realized.
According to a first aspect of the present application, a magnetic resonance imaging system with integrated neuromodulation is provided. The method comprises the following steps: the stimulation device comprises a frame, a head supporting base and a stimulation device, wherein the frame comprises a frame bottom positioned beside the head supporting base, a frame top positioned above the frame bottom and a frame side part connected between the frame bottom and the frame top, the frame bottom, the frame top and the frame side part define a head accommodating area, one open end of the head accommodating area is an shoulder placing area, the other open end of the head accommodating area forms a first stimulation device mounting area, and a second stimulation device mounting area is arranged on the frame top; the head magnetic resonance radio-frequency coil comprises a flexible wearable base and a radio-frequency coil arranged in the flexible wearable base, and is also provided with a sight hole and an equipment position-giving area respectively; the stimulation device comprises a first stimulation device and a second stimulation device, the first stimulation device and the second stimulation device are installed in the first device installation area and the second device installation area simultaneously or in a time-sharing mode respectively, the first stimulation device is an electromagnetic stimulation device and acts on a testee through the first channel, and the second stimulation device is a visual stimulation device and acts on the testee through the second channel.
Optionally, the first stimulation device comprises: transcranial Magnetic Stimulation (TMS) equipment for short; and/or transcranial Direct Current Stimulation equipment, referred to as tDCS equipment for short; and/or, a magnetic resonance guided Focused Ultrasound interventional therapy MR guide Focused Ultrasound device, MRgFUS device for short. Optionally, the visual stimulation device includes a Virtual Reality device, VR device for short.
Optionally, the head mri coil is a strip when being unfolded, and is worn on the head of the subject in a cylindrical structure which is rolled along the long edge of the strip and can wrap the head of the subject.
Optionally, the two ends of the length of the band-shaped body are provided with an adhering structure which can be adhered to each other and can adjust the inner diameter of the cylindrical structure by changing the adhering position so as to adjust the wearing tightness of the cylindrical structure.
Optionally, a raised face-conformable liner is disposed on the inner side of the head magnetic resonance radio frequency coil; or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, the lining comprises an orbit attaching part, the orbit attaching part is provided with a groove with the edge arranged along the periphery of the orbit, and the second channel is positioned in the groove; or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, the lining comprises an orbit attaching part, the orbit attaching part is provided with a groove with the edge arranged along the periphery of the orbit, the groove is a flat annular groove which covers two orbits of the eyes at the same time, and the second channel is positioned in the groove; or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, the lining comprises an orbit attaching part, the orbit attaching part is provided with a nose bridge transverse supporting part, and the nose bridge transverse supporting part is provided with an arc structure which is thin in the middle and thick at two ends in the thickness direction; or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, and the lining comprises an eye socket attaching part and a forehead attaching part; or the inner side of the head magnetic resonance radio frequency coil is provided with a convex face-fitting lining, the lining comprises an eye socket fitting part and a forehead fitting part, and the forehead fitting part is obliquely arranged so as to simultaneously extend in the forehead width direction and the forehead height direction.
According to a second aspect of the present application, a head magnetic resonance radio frequency coil for magnetic resonance imaging is provided, which includes a flexible wearable base and a radio frequency coil disposed in the flexible wearable base, wherein a viewing hole and an equipment abdicating area are further disposed on the head magnetic resonance radio frequency coil, when the head magnetic resonance radio frequency coil is worn on the head of a subject, the equipment abdicating area provides a first channel for exposing a specific part of the head of the subject, and the viewing hole provides a second channel for the subject to observe outwards.
Optionally, the two ends of the length of the band-shaped body are provided with an adhering structure which can be adhered to each other and can adjust the inner diameter of the cylindrical structure by changing the adhering position so as to adjust the wearing tightness of the cylindrical structure.
Optionally, a raised face-conformable liner is disposed on the inner side of the head magnetic resonance radio frequency coil; or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, the lining comprises an orbit attaching part, the orbit attaching part is provided with a groove with the edge arranged along the periphery of the orbit, and the second channel is positioned in the groove; or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, the lining comprises an orbit attaching part, the orbit attaching part is provided with a groove with the edge arranged along the periphery of the orbit, the groove is a flat annular groove which covers two orbits of the eyes at the same time, and the second channel is positioned in the groove; or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, the lining comprises an orbit attaching part, the orbit attaching part is provided with a nose bridge transverse supporting part, and the nose bridge transverse supporting part is provided with an arc structure which is thin in the middle and thick at two ends in the thickness direction; or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, and the lining comprises an eye socket attaching part and a forehead attaching part; or the inner side of the head magnetic resonance radio frequency coil is provided with a convex face-fitting lining, the lining comprises an eye socket fitting part and a forehead fitting part, and the forehead fitting part is obliquely arranged so as to simultaneously extend in the forehead width direction and the forehead height direction.
According to a third aspect of the present application, there is provided a magnetic resonance imaging method integrating neuromodulation, in which, using the system of the first aspect, magnetic resonance imaging is performed while simultaneously or time-divisionally acting on a subject by at least one stimulation means of the first and second stimulation devices.
The magnetic resonance imaging system and the magnetic resonance imaging method can be used for carrying out magnetic resonance imaging by combining a brain function intervention regulation and control means of generating a physical field by an electromagnetic stimulation device on the basis of the traditional functional magnetic resonance imaging. Therefore, the limitation of the traditional functional magnetic resonance imaging in the aspect of visual stimulation can be broken through, and meanwhile, the brain function intervention regulation and control means of the physical field generated by the electromagnetic stimulation equipment can be changed from a passive positioning treatment means to a functional magnetic resonance imaging stimulation means. By fMRI scanning under electromagnetic stimulation, the mode of nerve loop function change of each individual can be revealed, and then individualized functional targets are defined, and further individualized accurate medical treatment on mental diseases is realized. The system for magnetic resonance imaging and the head magnetic resonance radio frequency coil are simple and reasonable in structural design, and different stimulating devices can be ingeniously combined on the basis of utilizing the existing magnetic resonance imaging equipment.
The present application will be further described with reference to the following drawings and detailed description. Additional aspects and advantages of the present application will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the present application.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, are included to assist in understanding the present application and are included to explain, by way of illustration, the present application and the description thereof with regard to the present specification, and are not intended to limit the embodiments of the present application in any way. In the drawings:
fig. 1 is a schematic structural diagram of a system for magnetic resonance imaging according to an embodiment of the present application.
Fig. 2 is a schematic view of the product shown in fig. 1 at another angle.
Fig. 3 is a schematic structural diagram of a head magnetic resonance radio frequency coil according to an embodiment of the present application.
Fig. 4 is a schematic view of the product shown in fig. 3 in a three-dimensional state.
Detailed Description
The present application will now be described more fully hereinafter with reference to the accompanying drawings. Those skilled in the art will be able to implement the teachings of the present application based on these teachings. Before describing the present application in conjunction with the drawings, it is noted that:
in the present specification, the technical solutions and the technical features provided in the respective portions including the following description may be combined with each other without conflict.
Reference throughout the following description to only a few embodiments, but not all embodiments of the present application, is intended to cover all other embodiments, which may be made by those skilled in the art without any inventive faculty, based on the embodiments of the present application.
The terms "comprising," "including," "having," and any variations thereof in this specification and claims and in any related parts thereof, are intended to cover non-exclusive inclusions.
Fig. 1 is a schematic structural diagram of a system for magnetic resonance imaging according to an embodiment of the present application. Fig. 2 is a schematic view of the product shown in fig. 1 at another angle. Fig. 3 is a schematic structural diagram of a head magnetic resonance radio frequency coil according to an embodiment of the present application. Fig. 4 is a schematic view of the product shown in fig. 3 in a three-dimensional state. As shown in fig. 1-4, a system for magnetic resonance imaging, comprising: a frame 10, a head magnetic resonance radio frequency coil 20 and a stimulation device 30. Wherein, the frame 10 comprises a frame bottom 11 for positioning beside a head base (i.e. a headrest, which is a part of an existing magnetic resonance imaging device), a frame top 12 above the frame bottom 11, and a frame side 13 connected between the frame bottom 11 and the frame top 12, the frame bottom 11, the frame top 12, and the frame side 13 define a head accommodating area 14, one end of the head accommodating area 14 is open and the outside is a shoulder placing area 15 of the human subject 40, the other end is open and forms a first stimulation device mounting area 16, and a second stimulation device mounting area 17 is arranged on the frame top 12; the head magnetic resonance radio-frequency coil 20 comprises a flexible wearable base 21 (which may be made of EVA material, i.e., ethylene-vinyl acetate copolymer material) and a radio-frequency coil 22 disposed in the flexible wearable base 21, the head magnetic resonance radio-frequency coil 20 is further provided with a viewing hole 23 and an equipment escape area 24, when the head magnetic resonance radio-frequency coil 20 is worn on the head of the human subject 40, the equipment escape area 24 provides a first channel for exposing a specific part of the head of the human subject 40, and the viewing hole 23 provides a second channel for the human subject to observe outwards; the stimulation device 30 comprises a first stimulation device 31 and a second stimulation device 32, the first stimulation device 31 and the second stimulation device 32 are respectively installed in the first device installation area 16 and the second device installation area 17 at the same time or in a time-sharing manner, the first stimulation device 31 is an electromagnetic stimulation device and acts on the human subject 40 through the first channel, and the second stimulation device 32 is a visual stimulation device and acts on the human subject 40 through the second channel.
The first Stimulation device can be at least one or more of Transcranial Magnetic Stimulation (TMS) device, Transcranial Direct Current Stimulation (tDCS) device and Magnetic resonance guided Focused Ultrasound interventional therapy (MRgFUS) device. The second stimulation device may be a Virtual Reality device, VR device for short. TMS equipment, tDCS equipment, MRgFUS equipment and VR equipment are all prior art. The TMS equipment and the TDCS equipment act on the brain by using a pulse magnetic field or weak direct current to change the membrane potential of cortical nerve cells so as to influence intracerebral metabolism and neuroelectric activity, thereby causing a series of physiological and biochemical reactions. The TMS device generates an induced magnetic field through the skull by a pulsed current in a coil, creating a reverse induced current in the brain, which can activate neurons and cause microscopic changes in axons, further causing electrophysiological and functional changes. tDCS devices function by modulating autonomic neuronal network activity; at the neuronal level, the basic mechanism for regulating the excitation of cortex is the change of hyperpolarization or depolarization of resting membrane potential according to the polarity difference of stimulation, and the microenvironment of synapse can be regulated, such as the change of the activity of NMDA receptor or GABA, thereby playing a role in regulating synaptic plasticity. With the accumulation of clinical evidence, the neural regulation and control technologies such as TMS equipment and tDCS equipment have gradually evolved into the regulation and control treatment means for diseases. The MRgFUS device is an updated non-ionizing radiation and non-invasive precise regulation and control technology, the intervention treatment mode utilizes the mechanical effect (sound intensity and frequency change) of ultrasonic waves to activate or inhibit nerve cells, and has the characteristics of precise positioning, small action area, high targeting property, good multi-parameter regulation and control performance, capability of stimulating intracranial deep tissues and the like, the action range of focused ultrasound can be precisely in the micron level, and the deeper parts of human brain tissues can be predicted. Overall, MRgFUS devices can achieve more accurate and effective intervention and control of brain function than TMS devices or tDCS devices.
It will also be seen from the above description that the TMS device and/or TDCS device acts primarily on the superficial brain structures and the MRgFUS device acts primarily on the deep brain structures, and therefore, when the first stimulation device comprises a TMS device and/or TDCS device in combination with an MRgFUS device, a more comprehensive transcranial stimulation need is met.
The system for magnetic resonance imaging is mainly characterized in that: the invention creatively proposes that the head magnetic resonance radio frequency coil 20 is wearable in nature, and a visual hole 23 and a device abduction area 24 are designed on the head magnetic resonance radio frequency coil 20, on the basis of which, the frame 10 is externally arranged on the head magnetic resonance radio frequency coil 20 and is used for providing a first stimulation device installation area 16 and a second stimulation device installation area 17, when the first stimulation device 31 and the second stimulation device 32 are respectively installed on the first device installation area 16 and the second device installation area 17 at the same time or in time, the first stimulation device 31 acts on the human subject 40 through the device abduction area 24, and the second stimulation device 32 acts on the human subject 40 through the visual hole 23. The main advantage of the above features is that the whole system achieves extremely optimized utilization of space, which can make the whole system occupy an exceptionally small space, and therefore, the system can be directly installed in the channel of the existing magnetic resonance imaging device.
As a preferred embodiment of the head magnetic resonance radio frequency coil 20, as shown in fig. 1 to 4, the head magnetic resonance radio frequency coil 20 is a strip-shaped body when being unfolded, and is worn on the head of the human subject 40 in a cylindrical structure capable of wrapping the head of the human subject by being rolled along the long sides of the strip-shaped body. In addition, the both ends of the length of banded body can also set up can paste each other and can adjust through changing the position of pasting thereby the internal diameter of cylindric structure adjusts the structure 25 (such as magic subsides) of pasting of the wearing elasticity of cylindric structure. The cylindrical structure is advantageous in that the end portion thereof is open to expose the entire crown of the head of the human subject 40, and therefore the first stimulation device 31 can cover both the crown of the head of the human subject 40 and the side surface and even the bottom surface of the head of the human subject 40 from the gap between the head of the human subject 40 and the cylindrical structure, which can be changed by adjusting the tightness of wearing of the cylindrical structure.
In addition, as shown in fig. 3-4, the inner side of the head mri coil 20 is provided with a convex face-conformable liner 26. The lining 26 can help the wearing and positioning of the head magnetic resonance radio frequency coil 20, so that a gap is reserved between the worn head magnetic resonance radio frequency coil 20 and the head of the human subject 40, and the wearing comfort of the head magnetic resonance radio frequency coil 20 is improved. The liner 26 may be made of a soft, skin-friendly material. In order to make the design of the inner liner 26 more reasonable, the inner liner 26 may include an orbital fit 261, the orbital fit 261 is provided with a groove 262 with an edge arranged along the periphery of the orbit, and the second channel is positioned in the groove 262; the recess 262 is preferably an annular, flat recess that covers both eye sockets. Optionally, the orbit fitting portion 261 has a nose bridge lateral support portion 264, and the nose bridge lateral support portion 264 has an arc-shaped structure that is thin in the middle in the thickness direction and thick at both ends. Optionally, the liner 26 further includes orbital fit and forehead fit 263; the forehead contact portion 263 is preferably inclined so as to extend in both the forehead width direction and the forehead height direction.
In the case of using the above-described system for magnetic resonance imaging, the method for magnetic resonance imaging of the embodiment of the present application simultaneously or time-divisionally acts on a subject by at least one of the first stimulation device 31 and the second stimulation device 32 (when the first stimulation device 31 includes at least two devices, at least one of the at least two devices) and performs magnetic resonance imaging. Specifically, the VR device and the MRgFUS device may operate simultaneously, and the VR device and the TMS device or tDCS device may operate simultaneously.
Those of ordinary skill in the art will be able to implement the embodiments of the present application based on the foregoing description. Based on the above description provided herein, all other embodiments that may be derived by one of ordinary skill in the art without making any creative effort shall fall within the protection scope of the present application.
Claims (10)
1. An integrated neuromodulation magnetic resonance imaging system, comprising:
the stimulation device comprises a frame, a head supporting base and a stimulation device, wherein the frame comprises a frame bottom positioned beside the head supporting base, a frame top positioned above the frame bottom and a frame side part connected between the frame bottom and the frame top, the frame bottom, the frame top and the frame side part define a head accommodating area, one open end of the head accommodating area is an shoulder placing area, the other open end of the head accommodating area forms a first stimulation device mounting area, and a second stimulation device mounting area is arranged on the frame top;
the head magnetic resonance radio-frequency coil comprises a flexible wearable base and a radio-frequency coil arranged in the flexible wearable base, and is also provided with a sight hole and an equipment position-giving area respectively;
the stimulation device comprises a first stimulation device and a second stimulation device, the first stimulation device and the second stimulation device are installed in the first device installation area and the second device installation area simultaneously or in a time-sharing mode respectively, the first stimulation device is an electromagnetic stimulation device and acts on a testee through the first channel, and the second stimulation device is a visual stimulation device and acts on the testee through the second channel.
2. The system of claim 1, wherein the first stimulation device comprises: transcranial Magnetic Stimulation (TMS) equipment for short; and/or transcranial Direct Current Stimulation equipment, referred to as tDCS equipment for short; and/or, a magnetic resonance guided Focused Ultrasound interventional therapy MR guide Focused Ultrasound device, MRgFUS device for short.
3. The system of claim 1, wherein: the visual stimulation equipment comprises Virtual Reality equipment, VR equipment for short.
4. A system according to any one of claims 1 to 3, wherein: the head magnetic resonance radio frequency coil is a strip-shaped body when being unfolded and is worn on the head of a testee through a cylindrical structure which is rolled along the long edge of the strip-shaped body and can wrap the head of the testee.
5. The system of claim 4, wherein: the two ends of the length of the band-shaped body are provided with pasting structures which can be pasted with each other and can adjust the inner diameter of the cylindrical structure by changing the pasting position so as to adjust the wearing tightness of the cylindrical structure.
6. A system according to any one of claims 1 to 3, wherein: the inner side of the head magnetic resonance radio frequency coil is provided with a convex face conformable lining;
or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, the lining comprises an orbit attaching part, the orbit attaching part is provided with a groove with the edge arranged along the periphery of the orbit, and the second channel is positioned in the groove;
or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, the lining comprises an orbit attaching part, the orbit attaching part is provided with a groove with the edge arranged along the periphery of the orbit, the groove is a flat annular groove which covers two orbits of the eyes at the same time, and the second channel is positioned in the groove;
or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, the lining comprises an orbit attaching part, the orbit attaching part is provided with a nose bridge transverse supporting part, and the nose bridge transverse supporting part is provided with an arc structure which is thin in the middle and thick at two ends in the thickness direction;
or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, and the lining comprises an eye socket attaching part and a forehead attaching part;
or the inner side of the head magnetic resonance radio frequency coil is provided with a convex face-fitting lining, the lining comprises an eye socket fitting part and a forehead fitting part, and the forehead fitting part is obliquely arranged so as to simultaneously extend in the forehead width direction and the forehead height direction.
7. A head magnetic resonance radio frequency coil for magnetic resonance imaging, characterized by: contain flexible wearable base and set up the radio frequency coil in this flexible wearable base, still be provided with on the head magnetic resonance radio frequency coil respectively and look hole and equipment and let the position district, after this head magnetic resonance radio frequency coil dresses in the person's head, equipment lets the position district provide the first passageway that makes person's head particular part expose, look the hole and provide the second passageway that the person was outwards observed.
8. The coil of claim 7, wherein: the two ends of the length of the band-shaped body are provided with pasting structures which can be pasted with each other and can adjust the inner diameter of the cylindrical structure by changing the pasting position so as to adjust the wearing tightness of the cylindrical structure.
9. The coil of claim 7, wherein: the inner side of the head magnetic resonance radio frequency coil is provided with a convex face conformable lining;
or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, the lining comprises an orbit attaching part, the orbit attaching part is provided with a groove with the edge arranged along the periphery of the orbit, and the second channel is positioned in the groove;
or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, the lining comprises an orbit attaching part, the orbit attaching part is provided with a groove with the edge arranged along the periphery of the orbit, the groove is a flat annular groove which covers two orbits of the eyes at the same time, and the second channel is positioned in the groove;
or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, the lining comprises an orbit attaching part, the orbit attaching part is provided with a nose bridge transverse supporting part, and the nose bridge transverse supporting part is provided with an arc structure which is thin in the middle and thick at two ends in the thickness direction;
or a convex face-attachable lining is arranged on the inner side of the head magnetic resonance radio frequency coil, and the lining comprises an eye socket attaching part and a forehead attaching part;
or the inner side of the head magnetic resonance radio frequency coil is provided with a convex face-fitting lining, the lining comprises an eye socket fitting part and a forehead fitting part, and the forehead fitting part is obliquely arranged so as to simultaneously extend in the forehead width direction and the forehead height direction.
10. A method of magnetic resonance imaging integrating neuromodulation, the method comprising: in case of using the system according to any of claims 1-6, the magnetic resonance imaging is performed by simultaneously or time-divisionally acting on the subject by at least one stimulation means of the first and second stimulation devices.
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