CN114199662B - Clinical laboratory blood mixing method - Google Patents
Clinical laboratory blood mixing method Download PDFInfo
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- CN114199662B CN114199662B CN202111541624.0A CN202111541624A CN114199662B CN 114199662 B CN114199662 B CN 114199662B CN 202111541624 A CN202111541624 A CN 202111541624A CN 114199662 B CN114199662 B CN 114199662B
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- 239000008280 blood Substances 0.000 title claims abstract description 128
- 210000004369 blood Anatomy 0.000 title claims abstract description 128
- 238000002156 mixing Methods 0.000 title claims abstract description 99
- 238000000034 method Methods 0.000 title claims abstract description 12
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims abstract description 69
- 229960002897 heparin Drugs 0.000 claims abstract description 69
- 229920000669 heparin Polymers 0.000 claims abstract description 69
- 239000007788 liquid Substances 0.000 claims abstract description 69
- 238000003756 stirring Methods 0.000 claims abstract description 38
- 238000001125 extrusion Methods 0.000 claims abstract description 26
- 239000011259 mixed solution Substances 0.000 claims abstract description 17
- 239000000463 material Substances 0.000 claims abstract description 13
- 238000007599 discharging Methods 0.000 claims abstract description 8
- 230000007246 mechanism Effects 0.000 claims description 48
- 238000012546 transfer Methods 0.000 claims description 36
- 238000013459 approach Methods 0.000 claims description 10
- 230000009471 action Effects 0.000 claims description 8
- 230000005484 gravity Effects 0.000 claims description 4
- 238000005381 potential energy Methods 0.000 claims description 4
- 238000004891 communication Methods 0.000 claims 4
- 239000000243 solution Substances 0.000 description 7
- 230000001502 supplementing effect Effects 0.000 description 5
- 230000004927 fusion Effects 0.000 description 4
- 238000004026 adhesive bonding Methods 0.000 description 3
- 239000003146 anticoagulant agent Substances 0.000 description 3
- 229940127219 anticoagulant drug Drugs 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000000737 periodic effect Effects 0.000 description 2
- 230000001360 synchronised effect Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention discloses a clinical laboratory blood mixing method which is characterized by comprising the following steps: s1: designing a blood mixing device; s2: when the blood and heparin mixed solution in the mixing shell in the blood mixing device is uniformly mixed, medical staff starts a driving motor, and the driving motor drives a stirring shaft, a sleeve and stirring blades to synchronously rotate clockwise to stir the blood and heparin mixed solution in the mixing shell, so that the mixing rate of the blood and heparin is enhanced; s3: when the extrusion head rotates clockwise, the convex disc is driven to rotate clockwise synchronously, and the rotating stirring shaft drives the convex disc to slide on the inner wall of the connecting frame; s4: when the slide bar moves left and right periodically, the connecting rod is driven to move synchronously, so that the mixing shell is driven to slide left and right periodically at the three tops of the slide groove, and the mixed solution of blood and heparin in the mixing shell is vibrated; s5: when the mixed liquid in the uniformly mixed shell is required to be taken, the container is only required to be placed into the storage box from the position of the material taking opening, and the valve of the material discharging opening is opened to take the liquid.
Description
Technical Field
The invention relates to the technical field of blood mixing, in particular to a clinical laboratory blood mixing method.
Background
In the hospital test, for some specific items, human blood and an anticoagulant are required to be mixed in a blood collection bottle, heparin is the best anticoagulant in the measurement of blood chemical components, but the blood collection bottle is required to be shaken for a long time to fully and uniformly mix the blood and heparin.
The existing blood mixing device can only fuse the blood and heparin in the blood sampling bottle in a manual shaking mode, but when a blood sample is large, the manual shaking mode is adopted, so that the workload of medical staff is increased, the blood and the anticoagulant are easily mixed unevenly, and the accuracy of a test result is affected.
Disclosure of Invention
The invention aims to provide a clinical laboratory blood mixing method which has the advantages of good mixing effect and equal proportion of added blood and heparin.
In order to achieve the above purpose, the present invention provides the following technical solutions: the clinical laboratory blood mixing method is characterized by comprising the following steps of:
s1: designing a blood mixing device;
s2: when the blood and heparin mixed solution in the mixing shell (18) in the blood mixing device is mixed, medical staff starts a driving motor (5), the driving motor (5) drives a stirring shaft (6), a sleeve (8) and stirring blades (9) to synchronously rotate clockwise, the blood and heparin mixed solution in the mixing shell (18) is stirred, and the mixing rate of the blood and heparin is enhanced;
s3: when the extrusion head (16) rotates clockwise, the convex disc (7) is driven to rotate clockwise synchronously, the rotating stirring shaft (6) drives the convex disc (7) to slide on the inner wall of the connecting frame (17), the connecting frame (17) is driven to move left and right periodically, the first sliding rod (13) is driven to slide left and right periodically on the inner wall of the sliding sleeve (12), and meanwhile the first sliding rod (13) slides on the inner wall of the limiting notch (4), so that the mixing rate of blood and heparin is enhanced;
s4: when the first slide bar (13) periodically moves left and right, the connecting rod (14) is driven to synchronously move, so that the mixing shell (18) is driven to periodically slide left and right at the top of the third slide groove (20), and the mixed solution of blood and heparin in the mixing shell is oscillated;
s5: when the mixed liquid in the mixing shell (18) is required to be taken, the container is only required to be placed into the storage box (1) from the position of the material taking opening (2), and the valve of the material discharging opening (19) is opened to take the liquid.
In the scheme, a driving motor (5) is fixed on the upper surface of a storage box (1) of the blood mixing device, a mounting plate (10) is fixed on the inner wall of the storage box (1), and sliding sleeves (12) are fixed at the left end and the right end of the bottom of the mounting plate (10); the inner wall of the sliding sleeve (12) is connected with a first sliding rod (13) in a sliding manner, and one end, close to the driving motor (5), of each sliding rod (13) is fixedly provided with a connecting frame (17); the left side wall and the right side wall of the storage box (1) are both provided with limiting notches (4), and one end of the first sliding rod (13) far away from the connecting frame (17) is in sliding connection with the inner wall of the limiting notch (4); an output shaft of the driving motor (5) is coaxially fixed with a stirring shaft (6), the bottom end of the stirring shaft (6) extends into the uniformly-mixed shell (18), and the outer wall of the stirring shaft (6) is fixed with stirring blades (9) through a sleeve (8); a third sliding chute (20) is formed in the bottom of the inner wall of the storage box (1), the top of the third sliding chute (20) is connected with a mixing shell (18) in a sliding manner, and a connecting rod (14) is fixed between the top of the mixing shell (18) and the bottom of the first sliding rod (13); the heparin adding mechanism (36) for adding heparin is fixed on the upper surface of the storage box (1), the heparin adding mechanism (36) is located on the right side of the driving motor (5), the heparin adding mechanism (36) is identical to the blood adding mechanism (35) in structure, and the size of the heparin adding mechanism (36) is smaller than that of the blood adding mechanism (35).
In the scheme, the volume of the transfer box body (27) in the heparin adding mechanism (36) is one tenth of that of the transfer box body (27) in the blood adding mechanism (35).
In the scheme, a first spring (31) is arranged on the outer wall of the communicating pipe (26), the first spring (31) is located between the upper surface of the baffle plate (30) and the lower surface of the connecting shell (25), and a liquid guide pipe (24) is fixed on the upper side of the right side wall of the connecting shell (25).
In the scheme, one end of the liquid guide pipe (24) is communicated with the inner wall of the connecting shell (25), the other end of the liquid guide pipe (24) penetrates through the upper surface of the storage box (1) and extends into the mixing shell (18), and an arc surface disc (32) capable of being in contact with the bottom of the extrusion head (16) is fixed at the bottom of the baffle plate (30).
In the step S4, when the slide bar I (13) periodically moves left and right, the two groups of slide bars II (15) are driven to slide left and right on the inner walls of the slide groove II (11) and the slide groove I (3), when the two groups of slide bars II (15) slide left, the two groups of extrusion heads (16) are driven to synchronously move left, at the moment, the left extrusion heads (16) gradually approach to the cambered disc (32) in the blood adding mechanism (35) and further gradually upwards extrude the cambered disc (32) so as to drive the communicating tube (26) to move upwards, the communicating tube upwards can drive the baffle plate (30) to upwards extrude the cambered disc (32) and simultaneously drive the transfer box (27) to gradually move upwards, so that the top of the transfer box is gradually separated from the liquid level of blood stored in the storage shell (22), and simultaneously the communicating tube (26) drives the two groups of piston plates (28) to slide upwards on the inner wall of the connecting shell (25), at the moment, the liquid leakage holes (29) on the outer wall of the communicating tube (26) gradually approach to the nozzle position of the transfer box (27), the piston holes (29) are communicated with the nozzle position of the liquid guide tube (24) and the liquid guide tube (24) gradually flows out of the liquid guide tube (24) due to the action of the liquid guide tube (24) and the liquid flowing out of the communicating tube (26) through the communicating tube (28), the blood is introduced into the mixing housing (18) through the catheter (24), so that the blood is automatically added into the mixing housing (18).
In the step S4, when the second slide bar (15) moves rightward, the extrusion head (16) is gradually separated from the bottom of the arc surface disc (32), the arc surface disc (32) and the communicating pipe (26) start to move downward under the action of elastic potential energy of the first spring (31), the liquid leakage hole (29) is gradually separated from the pipe orifice of the liquid guide pipe (24), and meanwhile, the transfer box body (27) moves downward to enter blood to realize automatic liquid filling, so that the continuous addition of blood into the uniform mixing shell (18) is realized.
The beneficial effects are as follows:
according to the blood mixing method, the stirring shaft is driven by the driving motor to rotate clockwise, so that the sleeve and the stirring fan blades are driven to rotate clockwise synchronously, the blood and heparin mixed solution in the mixing shell is stirred, and the mixing speed of the blood and heparin is enhanced;
when the extrusion head rotates clockwise, the convex disc is driven to rotate clockwise synchronously, and because the stirring shaft is located at the eccentric position of the convex disc, the convex disc is driven to slide on the inner wall of the connecting frame when the stirring shaft rotates, and then the connecting frame is driven to periodically move left and right, and then the sliding rod I is driven to periodically slide left and right on the inner wall of the sliding sleeve, and meanwhile the sliding rod I can slide on the inner wall of the limiting notch, so that the mixing rate of blood and heparin is enhanced.
When the slide bar periodically moves left and right, can drive the connecting rod synchronous motion, and then drive the mixed casing and periodically slide left and right at three tops of spout, can vibrate blood and heparin mixed solution in the mixed casing, simultaneously, can collide with the vibration board when the mixed casing moves left and right, and then strengthen and vibrate the effect, can prevent simultaneously that the solution from gluing and gluing at mixed shells inner wall, inconvenient cleanness, through setting up spring two, can cushion the vibration power that produces during the collision.
When the slide bar I periodically moves left and right, the two groups of slide bars II are driven to slide left and right on the inner walls of the slide groove II and the slide groove I, when the two groups of slide bars II slide left, the two groups of extrusion heads are driven to synchronously move left, at the moment, the left extrusion heads gradually approach to the direction of the cambered surface disc in the blood adding mechanism and further gradually upwards extrude the cambered surface disc, further drive the communicating pipe to move upwards, the upward movement of the communicating pipe can drive the baffle plate to upwards extrude the cambered surface disc, and simultaneously drive the transfer box body to gradually move upwards, so that the top of the transfer box body is gradually separated from the liquid level of blood stored in the storage shell, simultaneously, the upward movement of the communicating pipe can drive the two groups of piston plates to slide upwards on the inner wall of the connecting shell, at this moment, the weeping hole of the outer wall of the communicating pipe gradually approaches to the pipe orifice of the transfer box body, so that the weeping hole is communicated with the pipe orifice of the liquid guide pipe, blood stored in the transfer box body flows into the communicating pipe under the action of gravity and flows out into the liquid guide pipe through the weeping hole, the piston plate is arranged to prevent blood from leaking out, the blood is led into the mixing shell through the liquid guide pipe, the function of automatically adding blood into the mixing shell is realized, and because the structure of the heparin adding mechanism is identical to that of the blood adding mechanism, when the right sideslip rod moves leftwards, the right extruding head is driven to extrude an arc surface disk in the heparin adding mechanism, and the function of continuously adding heparin into the mixing shell can be realized in the same way.
Drawings
FIG. 1 is a schematic view of a blood blending device used in the present invention;
FIG. 2 is a schematic view of a storage box of the blood mixing device according to the present invention;
FIG. 3 is a schematic view of a material outlet of a blood mixing device according to the present invention;
FIG. 4 is a schematic view of a mounting plate of a blood blending device used in the present invention;
FIG. 5 is a schematic view of a connecting frame of a blood mixing device according to the present invention;
FIG. 6 is a schematic view of a cam of a blood blending device according to the present invention;
FIG. 7 is a schematic view of a mixing housing of a blood mixing apparatus according to the present invention;
FIG. 8 is a schematic view of a blood adding mechanism of the blood mixing apparatus according to the present invention.
In the figure: 1. a storage box; 2. a material taking port; 3. a first chute; 4. a limit notch; 5. a driving motor; 6. a stirring shaft; 7. a cam; 8. a sleeve; 9. stirring fan blades; 10. a mounting plate; 11. a second chute; 12. a sliding sleeve; 13. a first slide bar; 14. a connecting rod; 15. a second slide bar; 16. an extrusion head; 17. a connection frame; 18. uniformly mixing the shell; 19. a discharge port; 20. a chute III; 21. a support column; 22. a storage housing; 23. a fluid supplementing pipe; 24. a catheter; 25. a connection housing; 26. a communicating pipe; 27. a transfer box body; 28. a piston plate; 29. a weeping hole; 30. a baffle; 31. a first spring; 32. an arc surface disk; 33. an oscillating plate; 34. a second spring; 35. a blood adding mechanism; 36. heparin adding mechanism.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention.
As shown in fig. 1-8, a clinical laboratory blood mixing method is characterized by comprising the following steps:
s1: designing a blood mixing device;
embodiment one:
as shown in fig. 1-5, a clinical laboratory blood mixing method comprises a storage box 1, a driving motor 5 is fixed in the middle position of the upper surface of the storage box 1, a mounting plate 10 is fixed on the inner wall of the storage box 1, sliding sleeves 12 are fixed at the left and right ends of the bottom of the mounting plate 10, a first sliding rod 13 is slidably connected to the inner wall of the sliding sleeve 12, a connecting frame 17 is fixed at one end, close to the driving motor 5, of each of the two groups of first sliding rods 13, limiting slots 4 are formed in the left and right side walls of the storage box 1, one end, far away from the connecting frame 17, of each of the first sliding rods 13 is slidably connected with the inner wall of the limiting slots 4, an output shaft of the driving motor 5 penetrates through the storage box 1 and the outer wall of the mounting plate 10, a stirring shaft 6 is fixed at the bottom of the inner wall of the storage box 1, a third sliding groove 20 is formed in the bottom of the inner wall of the storage box 1, a mixing shell 18 is slidably connected to the top of the third sliding groove 20, a connecting rod 14 is fixed between the top of the mixing shell 18 and the bottom of the first sliding rod 13, the bottom of the stirring shaft 6 extends into the mixing shell 18, a sleeve 8 is fixed on the outer wall of the stirring shaft 6, and stirring blades 9 for stirring solution in the mixing shell 18 are fixed.
When the mixed solution of the blood and the heparin in the mixing shell 18 is required to be mixed, the driving motor 5 is started, the stirring shaft 6 is driven to rotate clockwise through the driving motor 5, the sleeve 8 and the stirring fan blades 9 are driven to rotate clockwise synchronously, the mixed solution of the blood and the heparin in the mixing shell 18 is stirred, and the mixing rate of the blood and the heparin is enhanced.
As shown in fig. 4, the inner walls of the left and right sides of the storage box 1 are both fixed with a second spring 34, and one end of the second spring 34, which is close to the mixing shell 18, is fixed with a vibrating plate 33 for vibrating the solution in the mixing shell 18.
When the first 13 periodic left and right movement of slide bar, can drive connecting rod 14 synchronous motion, and then drive mixing casing 18 at spout three 20 periodic left and right sliding, can vibrate blood and heparin mixed solution in the mixing casing 18, simultaneously, can collide with vibration board 33 when mixing casing 18 moves about, and then strengthen the vibration effect, can prevent simultaneously that the solution from gluing at mixing casing 18 inner wall, inconvenient cleanness, through setting up spring two 34, can cushion the vibration power that produces during the collision.
As shown in fig. 3-4, a discharging hole 19 for discharging solution is arranged at the bottom of the front surface of the mixing shell 18, and a material taking hole 2 is arranged at the front surface of the storage box 1 opposite to the discharging hole 19.
When the mixed liquid in the mixing shell 18 is required to be taken, the container is only required to be placed into the storage box 1 from the position of the material taking opening 2, and the valve of the material discharging opening 19 is opened to take the liquid.
Embodiment two:
as shown in fig. 6, on the basis of the first embodiment, further expansion is performed: the outer wall of the stirring shaft 6 is fixed with a convex disc 7, the stirring shaft 6 is positioned at the eccentric position of the convex disc 7, and the convex disc 7 is in sliding connection with the inner wall of the connecting frame 17.
When the extrusion head 16 rotates clockwise, the convex disc 7 is driven to rotate clockwise synchronously, and when the stirring shaft 6 rotates, the convex disc 7 is driven to slide on the inner wall of the connecting frame 17 due to the fact that the stirring shaft 6 is located at the eccentric position of the convex disc 7.
As shown in fig. 4, the left and right sides of the upper surface of the storage box 1 are provided with a first chute 3, the lower part of the upper surface of the mounting plate 10 opposite to the first chute 3 is provided with a second chute 11, one side of the first left sideslip rod 13 close to the connecting frame 17 and one side of the first right sideslip rod 13 far away from the connecting frame 17 are both fixed with a second slide rod 15, the second slide rod 15 is in sliding connection with the second chute 11 and the inner wall of the first chute 3, and the top of the second slide rod 15 is fixed with an extrusion head 16.
And then drive connecting frame 17 periodical left and right movement, and then drive slide bar one 13 periodical left and right sliding at sliding sleeve 12 inner wall, slide bar one 13 can slide at spacing notch 4 inner wall simultaneously, reinforcing blood and heparin's mixing rate.
Embodiment III:
as shown in fig. 8, on the basis of the second embodiment, further expansion is performed: the left side of the upper surface of the storage box 1 is fixed with a blood adding mechanism 35 for adding blood, the blood adding mechanism 35 comprises a support column 21, the bottom end of the support column 21 is fixed with the upper surface of the storage box 1, the top end of the support column 21 is fixed with a storage shell 22, the upper surface of the storage shell 22 is fixed with a liquid supplementing pipe 23 for supplementing liquid in the storage shell 22, the bottom of the storage shell 22 is fixed with a connecting shell 25, the bottom of the inner wall of the storage shell 22 is provided with a through hole, the inner wall of the through hole is axially and slidably connected with a communicating pipe 26, the top end of the communicating pipe 26 extends into the storage shell 22 and is fixed with a transfer box 27, and the bottom end of the communicating pipe 26 penetrates through the lower surface of the connecting shell 25 and is fixed with a baffle 30.
When the slide bars 13 move left and right periodically, the two groups of slide bars 15 are driven to slide left and right on the inner walls of the slide grooves 11 and 3, when the two groups of slide bars 15 slide left, the two groups of extrusion heads 16 are driven to move left synchronously, at this time, the left extrusion heads 16 gradually approach the direction of the cambered surface disc 32 in the blood adding mechanism 35, further gradually upwards extrude the cambered surface disc 32, further drive the communicating pipe 26 to move upwards, the upward movement of the communicating pipe 26 drives the baffle 30 to upwards extrude the cambered surface disc 32, and simultaneously drives the transfer box 27 to gradually move upwards, so that the top of the transfer box 27 is gradually separated from the liquid level of blood stored in the storage shell 22, and simultaneously, when the communicating pipe 26 moves upwards, the two groups of piston plates 28 are driven to slide upwards on the inner wall of the connecting shell 25, at this time, the liquid leakage holes 29 of the outer wall of the communicating pipe 26 gradually approach the mouth of the transfer box 27, so that the liquid leakage holes 29 are communicated with the mouth of the liquid guide tube 24, at this time, the blood stored in the transfer box 27 flows into the communicating pipe 26 due to the action of gravity, and flows out into the liquid guide tube 24, and the liquid guide tube 24 through the liquid leakage holes 29, and the automatic evenly-mixing function of the blood is realized by setting up the plate 28, and the blood is added into the shell 18.
As shown in fig. 8, the right outer wall of the communicating tube 26 is provided with a drain hole 29, the upper and lower sides of the outer wall of the communicating tube 26 opposite to the drain hole 29 are both sleeved with a piston plate 28, the piston plate 28 is slidably connected with the inner wall of the connecting housing 25, the outer wall of the communicating tube 26 is provided with a first spring 31, the first spring 31 is located between the upper surface of the baffle 30 and the lower surface of the connecting housing 25, the upper side of the right side wall of the connecting housing 25 is fixed with a liquid guide tube 24, one end of the liquid guide tube 24 is communicated with the inner wall of the connecting housing 25, the other end of the liquid guide tube 24 penetrates the upper surface of the storage box 1 and extends into the mixing housing 18, and a cambered surface disc 32 capable of contacting the bottom of the extrusion head 16 is fixed at the bottom of the baffle 30.
When the second slide bar 15 moves rightwards, the extrusion head 16 is gradually separated from the bottom of the arc surface disc 32, the arc surface disc 32 and the communicating pipe 26 start to move downwards under the action of elastic potential energy of the first spring 31, the liquid leakage hole 29 is gradually separated from the pipe opening of the liquid guide pipe 24, and meanwhile, the transfer box 27 moves downwards to enter blood, so that an automatic liquid supplementing function is realized, and the function of continuously adding blood into the uniform mixing shell 18 is realized.
As shown in fig. 8, a heparin adding mechanism 36 for adding heparin is fixed on the upper surface of the storage box 1, the heparin adding mechanism 36 is located on the right side of the driving motor 5, the structure of the heparin adding mechanism 36 is identical to that of the blood adding mechanism 35, the volume of the heparin adding mechanism 36 is smaller than that of the blood adding mechanism 35, and the volume of the transfer box body 27 in the heparin adding mechanism 36 is one tenth of that of the transfer box body 27 in the blood adding mechanism 35.
Because the blood and heparin are added simultaneously, the volume of the heparin adding mechanism 36 is smaller than that of the blood adding mechanism 35, and the volume of the transfer box body 27 in the heparin adding mechanism 36 is one tenth of that of the transfer box body 27 in the blood adding mechanism 35, the adding ratio is 10:1 when the blood and the heparin are added each time, the adding precision of the blood and the heparin is improved, and the phenomenon that the fusion degree of the blood and the heparin is insufficient or the fusion is excessive due to certain error caused by manual adding of workers is prevented.
S2: when the blood and heparin mixed solution in the mixing shell 18 in the blood mixing device is mixed, medical staff starts the driving motor 5, and the driving motor 5 drives the stirring shaft 6, the sleeve 8 and the stirring fan blades 9 to synchronously rotate clockwise, so that the blood and heparin mixed solution in the mixing shell 18 is stirred, and the mixing rate of the blood and heparin is enhanced;
s3: when the extrusion head 16 rotates clockwise, the convex disc 7 is driven to rotate clockwise synchronously, the rotating stirring shaft 6 drives the convex disc 7 to slide on the inner wall of the connecting frame 17, the connecting frame 17 is driven to move left and right periodically, the first sliding rod 13 is driven to slide left and right periodically on the inner wall of the sliding sleeve 12, and meanwhile the first sliding rod 13 slides on the inner wall of the limiting notch 4, so that the mixing rate of blood and heparin is enhanced;
s4: when the first slide bar 13 periodically moves left and right, the connecting rod 14 is driven to synchronously move, so that the mixing shell 18 is driven to periodically slide left and right at the top of the third slide groove 20, and the mixed solution of blood and heparin in the mixing shell is vibrated;
in step S4, when the first slide bar 13 periodically moves left and right, the second slide bars 15 are driven to slide left and right on the inner walls of the second slide groove 11 and the first slide groove 3; when the two groups of slide bars II 15 slide leftwards, the two groups of extrusion heads 16 are driven to synchronously move leftwards, at the moment, the left extrusion head 16 gradually approaches to the direction of the cambered surface disk 32 in the blood adding mechanism 35, and then gradually upwards extrudes the cambered surface disk 32, and then drives the communicating pipe 26 to upwards move, the upward movement of the communicating pipe 26 drives the baffle 30 to upwards extrude the cambered surface disk 32, and simultaneously drives the transfer box 27 to gradually upwards move, so that the top of the transfer box 27 is gradually separated from the liquid level of blood stored in the storage shell 22, and simultaneously, the upward movement of the communicating pipe 26 drives the two groups of piston plates 28 to upwards slide on the inner wall of the connecting shell 25, at the moment, the liquid leakage hole 29 on the outer wall of the communicating pipe 26 gradually approaches to the position of the pipe orifice of the transfer box 27, so that the liquid leakage hole 29 is communicated with the position of the liquid guide tube 24, at the moment, the blood stored in the transfer box 27 flows into the communicating pipe 26 due to the action of gravity and flows out into the liquid guide tube 24, and the outward leakage of the blood is prevented from leaking out of the liquid leakage hole 29 through the piston plate 28, and the liquid guide 24 is guided into the mixing shell 18 through the liquid guide 24, so that the blood is automatically added into the mixing shell 18 due to the liquid guide tube 24;
when the second slide bar 15 moves rightwards, the extrusion head 16 is gradually separated from the bottom of the cambered surface disc 32, the cambered surface disc 32 and the communicating pipe 26 start to move downwards due to the action of elastic potential energy of the first spring 31, the liquid leakage hole 29 is gradually separated from the pipe opening of the liquid guide pipe 24, and meanwhile, the transfer box 27 moves downwards into blood to realize an automatic liquid supplementing function, and the operation is repeated to realize continuous addition of blood to the uniform mixing shell 18;
because the structure of the heparin adding mechanism 36 is the same as that of the blood adding mechanism 35, when the second right slide bar 15 moves leftwards, the right extrusion head 16 is driven to extrude the cambered surface disc 32 in the heparin adding mechanism 36, and the continuous heparin adding to the uniformly mixed shell 18 can be realized in the same way;
because the blood and heparin are added simultaneously, the volume of the heparin adding mechanism 36 is smaller than that of the blood adding mechanism 35, and the volume of the transfer box body 27 in the heparin adding mechanism 36 is one tenth of that of the transfer box body 27 in the blood adding mechanism 35, the adding ratio is 10:1 when the blood and the heparin are added each time, the adding precision of the blood and the heparin is improved, and the phenomenon that the fusion degree of the blood and the heparin is insufficient or the fusion is excessive due to certain error caused by manual adding of workers is prevented.
S5: when the mixed liquid in the mixing shell 18 is required to be taken, the container is only required to be placed into the storage box 1 from the position of the material taking opening 2, and the valve of the material discharging opening 19 is opened to take the liquid.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (2)
1. The clinical laboratory blood mixing method is characterized by comprising the following steps of:
s1: designing a blood mixing device; the blood mixing device is characterized in that a driving motor (5) is fixed on the upper surface of a storage box (1), a mounting plate (10) is fixed on the inner wall of the storage box (1), and sliding sleeves (12) are fixed at the left end and the right end of the bottom of the mounting plate (10); the inner wall of the sliding sleeve (12) is connected with a first sliding rod (13) in a sliding manner, and one end, close to the driving motor (5), of each sliding rod (13) is fixedly provided with a connecting frame (17); the left side wall and the right side wall of the storage box (1) are both provided with limiting notches (4), and one end of the first sliding rod (13) far away from the connecting frame (17) is in sliding connection with the inner wall of the limiting notch (4); an output shaft of the driving motor (5) is coaxially fixed with a stirring shaft (6), the bottom end of the stirring shaft (6) extends into the uniformly-mixed shell (18), and the outer wall of the stirring shaft (6) is fixed with stirring blades (9) through a sleeve (8); a third sliding chute (20) is formed in the bottom of the inner wall of the storage box (1), the top of the third sliding chute (20) is connected with a mixing shell (18) in a sliding manner, and a connecting rod (14) is fixed between the top of the mixing shell (18) and the bottom of the first sliding rod (13); the heparin adding mechanism (36) for adding heparin is fixed on the upper surface of the storage box (1), the heparin adding mechanism (36) is positioned on the right side of the driving motor (5), the heparin adding mechanism (36) has the same structure as the blood adding mechanism (35), and the volume of the heparin adding mechanism (36) is smaller than that of the blood adding mechanism (35);
the volume of the transfer box body (27) in the heparin adding mechanism (36) is one tenth of that of the transfer box body (27) in the blood adding mechanism (35); the outer wall of the communicating pipe (26) is provided with a first spring (31), the first spring (31) is positioned between the upper surface of the baffle (30) and the lower surface of the connecting shell (25), and a liquid guide pipe (24) is fixed on the upper side of the right side wall of the connecting shell (25);
one end of the liquid guide pipe (24) is communicated with the inner wall of the connecting shell (25), the other end of the liquid guide pipe (24) penetrates through the upper surface of the storage box (1) and extends into the mixing shell (18), and a cambered surface disc (32) which can be contacted with the bottom of the extrusion head (16) is fixed at the bottom of the baffle (30);
s2: when the blood and heparin mixed solution in the mixing shell (18) in the blood mixing device is mixed, medical staff starts a driving motor (5), the driving motor (5) drives a stirring shaft (6), a sleeve (8) and stirring blades (9) to synchronously rotate clockwise, the blood and heparin mixed solution in the mixing shell (18) is stirred, and the mixing rate of the blood and heparin is enhanced;
s3: when the extrusion head (16) rotates clockwise, the convex disc (7) is driven to rotate clockwise synchronously, the rotating stirring shaft (6) drives the convex disc (7) to slide on the inner wall of the connecting frame (17), the connecting frame (17) is driven to move left and right periodically, the first sliding rod (13) is driven to slide left and right periodically on the inner wall of the sliding sleeve (12), and meanwhile the first sliding rod (13) slides on the inner wall of the limiting notch (4), so that the mixing rate of blood and heparin is enhanced;
s4: when the first slide bar (13) periodically moves left and right, the connecting rod (14) is driven to synchronously move, so that the mixing shell (18) is driven to periodically slide left and right at the top of the third slide groove (20), and the mixed solution of blood and heparin in the mixing shell is oscillated;
in the step S4 of the process described above,
when the slide bars I (13) periodically move left and right, the two groups of slide bars II (15) are driven to slide left and right on the inner walls of the slide grooves II (11) and the slide grooves I (3), when the two groups of slide bars II (15) slide left, the two groups of extrusion heads (16) are driven to synchronously move left, at the moment, the left extrusion heads (16) gradually approach to the cambered surface disc (32) in the blood adding mechanism (35), and then gradually upwards extrude the cambered surface disc (32), and then drive the communication pipe (26) to move upwards, the upward movement of the communication pipe can drive the baffle plate (30) to upwards extrude the cambered surface disc (32), and simultaneously drive the transfer box (27) to gradually move upwards, so that the top of the transfer box is gradually separated from the liquid level of blood stored in the storage shell (22), and simultaneously the communication pipe (26) moves upwards, and drives the two groups of piston plates (28) to slide upwards on the inner wall of the connection shell (25), at the moment, the liquid leakage holes (29) on the outer wall of the communication pipe (26) gradually approach to the pipe opening position of the transfer box (27), the liquid leakage holes (29) are communicated with the pipe opening position of the liquid guide pipe (24), the liquid guide pipe position, the gravity of the transfer box (27) upwards presses the baffle plate (30) upwards, and the liquid can flow into the liquid guide pipe (24) through the inner liquid guide pipe (24) and the inner wall, and the blood is prevented from flowing out of the liquid guide pipe (24 through the inner wall through the transfer box (24), realize automatic blood addition into the mixing shell (18);
s5: when the mixed liquid in the mixing shell (18) is required to be taken, the container is only required to be placed into the storage box (1) from the position of the material taking opening (2), and the valve of the material discharging opening (19) is opened to take the liquid.
2. The method for mixing clinical laboratory blood according to claim 1, wherein: in the step S4, when the second slide bar (15) moves rightward, the extrusion head (16) is gradually separated from the bottom of the arc surface disc (32), the arc surface disc (32) and the communicating pipe (26) start to move downward under the action of elastic potential energy of the first spring (31), the liquid leakage hole (29) is gradually separated from the pipe orifice of the liquid guide pipe (24), and meanwhile, the transfer box body (27) moves downward to enter blood to realize automatic liquid filling, so that the continuous addition of blood into the uniform mixing shell (18) is realized.
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| US5121991A (en) * | 1990-09-03 | 1992-06-16 | Kabushiki Kaisha Nittec | Stirring device |
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| CN114199662A (en) | 2022-03-18 |
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