CN114195080A

CN114195080A - Parallel fluid distributor

Info

Publication number: CN114195080A
Application number: CN202010987751.2A
Authority: CN
Inventors: 潘晨
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-09-18
Filing date: 2020-09-18
Publication date: 2022-03-18

Abstract

The present invention relates to a parallel fluid distributor comprising: the microfluidic chip is provided with a single inlet and a single outlet, and a flow limiting channel is arranged between the inlet and the outlet, or the microfluidic chip is provided with a single inlet and a plurality of outlets, and a flow limiting channel is arranged between the inlet and each outlet; a plurality of pressure measurement elements; a base comprising, a well in which the microfluidic chip is placed, a base fluid inflow channel and a base fluid outflow channel; seals between the inlet of the microfluidic chip and the first end opening of the base fluid inflow channel, and between the outlet of the microfluidic chip and the first end opening of the base fluid outflow channel; a fixture for compression of the microfluidic chip, seal and groove plane. The parallel fluid distributor provided by the invention improves the precision of fluid distribution, and the microfluidic chip is more firm and durable and is easy to replace.

Description

Parallel fluid distributor

Technical Field

The invention relates to the field of parallel experiments, in particular to an assembly for parallel fluid distribution.

Background

The idea of parallel experiments is widely applied to the reaction performance research of the catalyst. In the parallel experiment process, a plurality of small-scale reactors are used for screening different catalysts under the same experiment condition or evaluating the reaction performance of the same catalytic material under different experiment conditions, so that the experiment efficiency can be obviously improved, and the research and development cost can be reduced.

Typically, in parallel experiments, the fluid flow to the parallel reactors is from the same fluid source, so that an even or proportional distribution of fluid is a critical loop.

In parallel experiments, the reactor design was small in order to save reaction raw materials and catalyst. In general, the amount of catalyst used in each reactor is from 0.1 to 5g, the liquid feed is from 0.5 to 5ml/h and the gaseous feed is from 0.1 to 1L/h. Therefore, small fluctuations in the flow rate of the reaction raw materials have a great influence on the experiment. In order to be able to compare the results of experiments performed in the individual reactors, it is important to accurately control the amount of reaction feed stream to each reactor.

W099/64160 discloses a method of fluid distribution for parallel experiments to achieve precise distribution of fluid flow in each reactor by using capillaries of the same internal diameter and length to change the viscosity of the fluid in the capillaries even by heating. In practice, however, it is almost impossible to obtain capillaries with exactly the same flow resistance due to the manufacturing process. Small differences in flow resistance between the individual capillaries can result in a large compromise in the control of the fluid flow in the individual reactors. Therefore, the flow resistance of the capillary needs to be calibrated and adjusted for many times, the method usually used is to change the length of the capillary, which is a very time-consuming and labor-consuming work, and the condition of the capillary needs to be concerned and calibrated and adjusted at any time along with the running of the experiment. In addition, the capillary is fragile, which also increases the difficulty of experimental operation.

Disclosure of Invention

The invention aims to provide a parallel fluid distributor, which adopts a microfluidic chip and solves the problems of complicated fluid distribution operation, frequent calibration and fragility of each reactor in parallel experiments in the related art.

According to the present invention, there is provided a parallel fluid dispenser comprising: the microfluidic chip is provided with a single inlet and a single outlet, and a flow limiting channel is arranged between the inlet and the outlet, or the microfluidic chip is provided with a single inlet and a plurality of outlets, and a flow limiting channel is arranged between the inlet and each outlet; the pressure measuring elements are connected with the outlet of the microfluidic chip and are used for measuring and reading the pressure of the outlet of the microfluidic chip in real time; a base including a groove, the groove having the same size as the microfluidic chip, the microfluidic chip being placed in the groove, a base fluid inflow channel and a base fluid outflow channel, a first end opening of the base fluid inflow channel and a first end opening of the base fluid outflow channel being in the groove, the first end opening of the base fluid inflow channel corresponding to an inlet position of the microfluidic chip, the first end opening of the base fluid outflow channel corresponding to an outlet position of the microfluidic chip, the second end opening of the base fluid inflow channel being at a side of the base, the second end opening of the base fluid outflow channel being at a side of the base; seals between the inlet of the microfluidic chip and the first end opening of the base fluid inflow channel, and between the outlet of the microfluidic chip and the first end opening of the base fluid outflow channel, the seals being annular rubber rings with central holes; a fixture for compression of the microfluidic chip, seal and groove plane. Further wherein the parallel flow distributor provides a plurality of microfluidic chips with a single inlet and a single outlet of equal flow resistance.

Further characterized wherein the parallel flow distributor provides a plurality of microfluidic chips with a single inlet and a single outlet of equal flow resistance.

Further, the parallel fluid distributor is provided with a microfluidic chip with a single inlet and a plurality of outlets, and the flow resistance of each flow limiting channel between the single inlet and the plurality of outlets is equal.

Further, the microfluidic chip is made of glass, quartz, silicon dioxide or metal.

Further characterized wherein a groove is provided in the base for receiving and retaining the seal, the groove being sized to match the profile of the seal.

Further, the groove arranged in the groove of the base is a cylindrical groove used for placing and fixing the sealing element, the diameter of the cylindrical groove is equal to the outer diameter of the sealing element, and the depth of the cylindrical groove is 1% -20% smaller than the height of the sealing element.

Further, the sealing device is characterized in that a groove is arranged in the groove of the base and is an annular groove, the annular groove is used for placing and fixing the sealing element, the width of the annular groove is equal to the annular diameter of the sealing element, and the depth of the annular groove is 1% -20% smaller than the height of the sealing element.

Further, the microfluidic chip is characterized in that the fixing pieces are cover plates with screw holes and bolts, the corresponding positions of the base are also provided with screw holes, and the cover plates and the bolts press the microfluidic chip, the sealing pieces and the groove planes tightly.

Further, a data line is connected to the pressure measuring element, and the data line is used for transmitting pressure data.

According to the parallel fluid distributor provided by the invention, the microfluidic chip is adopted to replace a capillary tube for fluid distribution, so that the precision of fluid distribution is improved, and the microfluidic chip is firmer and more durable and is easy to replace.

Drawings

The accompanying drawings, which are included to provide a further understanding of the invention, are incorporated in and constitute a part of this application, illustrate embodiment(s) of the invention and together with the description serve to explain the invention and do not constitute a limitation of the invention. In the drawings:

fig. 1 shows a first embodiment of a microfluidic chip according to an embodiment of the present invention.

Fig. 2 shows a second embodiment of a microfluidic chip according to an embodiment of the present invention.

Fig. 3 shows a first embodiment of a parallel fluid dispenser according to an embodiment of the invention.

Figure 4 shows a schematic view of the trough portion on the base of a first embodiment of the parallel fluid dispenser.

Fig. 5 shows a second embodiment of a parallel fluid dispenser according to an embodiment of the invention.

Figure 6 shows a schematic view of a trough portion on a base in a second embodiment of a parallel fluid dispenser.

Fig. 7 shows a schematic view of another embodiment of a slot portion on a base according to an embodiment of the invention.

Fig. 8 shows a third embodiment of a parallel fluid distributor according to an embodiment of the invention.

Detailed Description

It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to the embodiments with reference to the attached drawings.

In order to make the technical solutions of the present invention better understood, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

It should be noted that the terms "first," "second," and the like in the description and claims of the present invention and in the drawings described above are used for distinguishing between similar elements and not necessarily for describing a particular sequential or chronological order. It is contemplated that the data so used may be interchanged under appropriate circumstances in order to facilitate the embodiments of the invention described herein. Furthermore, the terms "comprises," "comprising," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements expressly listed, but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.

Fig. 1 shows a first embodiment of a microfluidic chip 1 according to an embodiment of the present invention.

The microfluidic chip 1 comprises a bottom sheet 5 and a top sheet 6. The microfluidic chip 1 further comprises a channel inlet 2, a channel outlet 3 and a flow-restricting channel 4. The channel inlet 2 and the channel outlet 3 are through channels on the bottom plate 5, and the flow limiting channel 4 is a channel with a small diameter machined or etched on the upper layer of the bottom plate 5 and is connected with the channel inlet 2 and the channel outlet 3. Processing the flow-limiting channel 4 on the bottom plate 5 is the most mature and convenient microchannel forming mode in the prior art, compared with the processing of a capillary tube, the processing precision of the diameter and the length of the microchannel is greatly improved, a uniform or customized microchannel can be processed, and the bottom plate 5 is firmer compared with the capillary tube. The flow restriction channel 4 can vary in channel diameter and length as desired, both of which affect the flow resistance of the microfluidic chip 1. The bottom sheet 5 and the top sheet 6 are bonded by gluing or welding, etc. depending on the material of the bottom sheet 5 and the top sheet 6 and the pressure of the fluid flowing through the microfluidic chip 1, the fluid can only flow in from the channel inlet 2, flow through the restricted flow channel 4, flow out from the channel outlet 3, and cannot leak out between the bottom sheet 5 and the top sheet 6.

The material of the microfluidic chip 1 may be selected according to the requirement, and may be made of glass, quartz, silicon dioxide, or metal.

In this embodiment, for the parallel reaction system, each fluid channel is provided with one microfluidic chip 1, and each microfluidic chip 1 can be processed into flow limiting channels 4 with different lengths and diameters according to experimental requirements, so as to achieve the purpose of distributing fluid flow according to experimental requirements. If different catalysts need to be screened under the same experimental conditions, the fluid flow needs to be evenly distributed, the length and the diameter of the flow limiting channel 4 of the microfluidic chip 1 are processed into the same specification, the same flow resistance of each microfluidic chip 1 is ensured, and the same fluid flow of each fluid channel can be ensured.

Fig. 2 shows a second embodiment of a microfluidic chip 1 according to an embodiment of the present invention.

In this embodiment, one microfluidic chip 1 is used instead of a plurality of microfluidic chips in the embodiment of fig. 1, which greatly saves the amount of microfluidic chips.

The microfluidic chip 1 likewise comprises a bottom sheet 5 and a top sheet 6. In contrast, the microfluidic chip 1 comprises a channel inlet 2 and a plurality of channel outlets 3, with a flow-restricting channel 4 being provided between the channel inlet 2 and each channel outlet 3. The channel inlet 2 and the plurality of channel outlets 3 are through channels on the bottom plate 5, and the flow restricting channel 4 is a small diameter channel machined or etched on the upper layer of the bottom plate 5. The bottom sheet 5 and the top sheet 6 are bonded by gluing or welding, etc. depending on the material of the bottom sheet 5 and the top sheet 6 and the pressure of the fluid flowing through the microfluidic chip 1, the fluid can only flow in from the channel inlet 2, flow through the restricted flow channel 4, flow out from the channel outlet 3, and cannot leak out between the bottom sheet 5 and the top sheet 6.

The microfluidic chip 1 can be processed into flow limiting channels 4 with different lengths and diameters according to experimental requirements, so that the purpose of distributing fluid flow according to experimental requirements is achieved. If different catalysts need to be screened under the same experimental conditions, the fluid flow needs to be evenly distributed, the length and the diameter of each flow limiting channel 4 of the microfluidic chip 1 are processed into the same specification, the same flow resistance of each flow limiting channel 4 is ensured, and the same fluid flow of each fluid channel can be ensured.

With the microfluidic chip 1 of this embodiment, the cost of using the microfluidic chip 1 can be greatly reduced for a parallel reaction system. Furthermore, the microfluidic chip 1 also integrates the function of a flow splitter, whereas with the embodiment of the microfluidic chip in fig. 1, a flow splitter is also required upstream of the parallel flow distributor.

The microfluidic chip 1 shown in fig. 2 has four channel outlets 3 and flow-restricting channels 4, and can be actually processed into 8 or 16 or even more channels according to the requirement.

Fig. 3 shows a first embodiment of a parallel fluid dispenser 10 according to an embodiment of the invention.

Fig. 4 shows a schematic view of a portion of the trough 14 on the base 13 in a first embodiment of the parallel fluid distributor 10.

In the first embodiment of the parallel fluid distributor 10, the parallel fluid distributor 10 employs a plurality of microfluidic chips 1 shown in fig. 1, and the number of microfluidic chips 1 is equal to the number of reactors of the parallel experimental apparatus, and 4 microfluidic chips 1 are shown in fig. 3, and may be actually configured to be 8 or 16, or even more, according to the requirement. The microfluidic chip 1 is placed in the groove 14 of the base 13, and the shape and size of the groove 14 are exactly the same as those of the microfluidic chip 1. The base 13 is provided with a fluid inflow channel 11 and a fluid outflow channel 12, a first end opening 25 of the fluid inflow channel 11 and a first end opening 26 of the fluid outflow channel 12 are both positioned on the bottom surface in the groove 14, the first end opening 25 of the fluid inflow channel 11 corresponds to the position of the channel inlet 2 of the microfluidic chip 1, and the first end opening 26 of the fluid outflow channel 12 corresponds to the position of the channel outlet 3 of the microfluidic chip 1. Furthermore, a seal 20 is provided between the channel inlet 2 of the microfluidic chip 1 and the first end opening 25 of the fluid inflow channel 11, and between the channel outlet 3 of the microfluidic chip 1 and the first end opening 26 of the base fluid outflow channel 12.

The condition of the portion of the base 13 in the slot 14 is better understood from figure 4. The groove 14 of the base 13 has a first end opening 25 of the fluid inflow channel 11, and the channel inlet 2 of the microfluidic chip 1 is located right above the opening 25, and a sealing member 20 is located between the two, and the sealing member 20 is an annular rubber ring with a central hole. In this way, the first end opening 25 of the fluid inflow channel 11, the central bore of the sealing member 20 and the channel inlet 2 of the microfluidic chip 1 form a through channel, and in a state in which the microfluidic chip 1 is compressed, no fluid leaks from the contact surface of the microfluidic chip 1 with the sealing member 20 or the contact surface of the bottom surface of the groove 14 with the sealing member 20. In addition, fig. 4 may also show a schematic diagram of the first end opening 26 of the fluid outflow channel 12 and the channel outlet 3 of the microfluidic chip 1. Of course, the arrangement of the trough portions of FIG. 4 may be applied to other embodiments of parallel fluid distributors.

The second end opening 27 of each fluid inlet channel 11 is connected to a fluid source (not shown) or to a flow diverter (not shown) which is in turn connected to a fluid source (not shown). The second end opening 28 of each fluid outflow channel 12 is connected to a separate reactor or reaction channel (not shown in the figures). It should be noted that the fluid source, flow splitter, reactor and reaction channels are not part of the parallel flow distributor 10 of the present invention.

The parallel fluid dispenser 10 also has a fixture for planar compression of the microfluidic chip 1, the seal 20 and the channel 14. The form of the holder is various, and the holder can be regarded as a holder as long as it can press the microfluidic chip 1, the sealing member 20 and the groove 14 in a plane. And as a convenient way of operation, the fixing member may be implemented by the cover plate 15 and the bolt 16. As shown in fig. 4, the cover plate 15 has screw holes, and the corresponding position of the base 13 also has screw holes, so that the microfluidic chip 1, the sealing member and the groove 14 are pressed in a plane by the cover plate 15 and the screw 16, thereby ensuring no fluid leakage.

The pressure measuring element 17 is connected to the fluid outflow channel 12 and further to the channel outlet 3 of the microfluidic chip 1 via a line 29 for reading in real time the pressure at the channel outlet 3 of each microfluidic chip 1.

By the parallel fluid distributor 10 of the present embodiment, fluid flow can be distributed by using microfluidic chips 1 with different specifications according to experimental requirements. If different catalysts need to be screened under the same experimental conditions, the microfluidic chip 1 with the same specification can be selected, so that the same fluid flow of each fluid channel can be ensured. The microfluidic chip 1 has the advantages of higher processing precision and stronger structure, and ensures that the parallel fluid distributor 10 of the embodiment controls the distribution of fluid more accurately, is more durable, and is easier to replace when a problem occurs in the microfluidic chip. Usually, each fluid outflow channel 12 is connected to a separate reactor, and the pressure measuring unit 17 also measures the pressure in the connected reactor and detects the pressure change during the reaction.

Fig. 5 shows a second embodiment of a parallel fluid dispenser 10 according to an embodiment of the invention.

Fig. 6 shows a schematic view of a portion of the trough 14 on the base 13 in a second embodiment of the parallel fluid distributor 10.

In the first embodiment of the parallel fluid distributor 10, the parallel fluid distributor 10 employs 1 microfluidic chip 1 of fig. 2, and the number of flow-limiting channels of the microfluidic chip 1 is equal to the number of reactors of the parallel experimental apparatus, and the microfluidic chip 1 shown in fig. 5 has four channel outlets 3 and flow-limiting channels 4, and can be actually processed into 8 or 16 or even more according to the requirement. With the microfluidic chip 1 of this embodiment, the cost of using the microfluidic chip 1 can be greatly reduced, and the channels for all fluid distribution can be integrated with only one microfluidic chip 1. Furthermore, the microfluidic chip 1 also integrates the function of a flow diverter. The microfluidic chip 1 is placed in the groove 14 of the base 13, and the shape and size of the groove 14 are exactly the same as those of the microfluidic chip 1. The base 13 has a fluid inflow channel 11 and a plurality of fluid outflow channels 12, the first end opening 25 of the fluid inflow channel 11 and the first end opening 26 of the fluid outflow channel 12 are both located on the bottom surface of the groove 14, and the first end opening 25 of the fluid inflow channel 11 corresponds to the position of the channel inlet 2 of the microfluidic chip 1, and the first end opening 26 of the fluid outflow channel 12 corresponds to the position of the channel outlet 3 of the microfluidic chip 1. Furthermore, a seal 20 is provided between the channel inlet 2 of the microfluidic chip 1 and the first end opening 25 of the fluid inflow channel 11, and between the channel outlet 3 of the microfluidic chip 1 and the first end opening 26 of the base fluid outflow channel 12.

The condition of the portion of the base 13 in the slot 14 is better understood from figure 6. Compared to the first embodiment of the parallel fluid dispenser 10, the base 13 of the second embodiment of the parallel fluid dispenser 10 is further provided with a cylindrical groove 23 in the groove 14 for placing and fixing the sealing member 20, the diameter of the cylindrical groove 23 is equal to the outer diameter of the sealing member 20, and the height of the sealing member 20 after being placed in the groove 23 is slightly higher than the bottom surface of the groove 14, so that the microfluidic chip 1 can be just pressed against the sealing member after being placed in the groove 14. The groove 14 of the base 13 has a first end opening 25 of the fluid inflow channel 11, and the channel inlet 2 of the microfluidic chip 1 is located right above the opening 25, and a sealing member 20 is located between the two, and the sealing member 20 is an annular rubber ring with a central hole. In this way, in the state that the microfluidic chip 1 is compressed, the first end opening 25 of the fluid inflow channel 11, the central hole of the sealing member 20 and the channel inlet 2 of the microfluidic chip 1 just form a through channel, and the fluid does not leak from the contact surface between the microfluidic chip 1 and the sealing member 20 or the contact surface between the bottom surface of the groove 14 and the sealing member 20. In addition, fig. 6 may also show a schematic diagram of the first end opening 26 of the fluid outflow channel 12 and the channel outlet 3 of the microfluidic chip 1. The method of fixing the sealing member 20 using the cylindrical groove 23 can prevent the fluid from leaking more effectively. Of course, the arrangement of the trough portions of FIG. 6 may be applied to other embodiments of parallel flow distributors.

The second end opening 27 of the fluid inflow channel 11 is connected to a fluid source (not shown in the figures). The second end opening 28 of each fluid outflow channel 12 is connected to a separate reactor or reaction channel (not shown in the figures). It should be noted that the fluid source, the reactor and the reaction channels are not part of the parallel flow distributor 10 of the present invention.

By the parallel fluid distributor 10 of the embodiment, the microfluidic chip 1 with the flow-limiting channels 4 with different flow resistances can be processed according to experimental requirements to distribute fluid flow. If different catalysts need to be screened under the same experimental conditions, the length and the diameter of each flow limiting channel 4 of the microfluidic chip 1 can be processed into the same specification, so that each flow limiting channel 4 has the same flow resistance, and the fluid flow of each fluid channel is ensured to be the same. The microfluidic chip 1 has the advantages of higher processing precision and stronger structure, and ensures that the parallel fluid distributor 10 of the embodiment controls the distribution of fluid more accurately, is more durable, and is easier to replace when a problem occurs in the microfluidic chip. Usually, each fluid outflow channel 12 is connected to a separate reactor, and the pressure measuring unit 17 also measures the pressure in the connected reactor and detects the pressure change during the reaction.

Fig. 7 shows a schematic view of another embodiment of a portion of the slot 14 on the base 13, according to an embodiment of the invention.

In this embodiment, there is also an annular groove 23 in the groove 14 of the base 13 for placing and fixing the sealing member 20, the width of the annular groove 23 is equal to the annular diameter of the sealing member 20, and the height of the sealing member 20 after being placed in the annular groove 23 is slightly higher than the bottom surface of the groove 14, so that the microfluidic chip 1 can be just pressed against the sealing member after being placed in the groove 14. The center of the annular groove 23 is the first end opening 25 of the fluid inflow channel, and the channel inlet 2 of the microfluidic chip 1 is right above the opening 25, and there is a sealing member 20 between them, and the sealing member 20 is an annular rubber ring with a central hole. In this way, in the state that the microfluidic chip 1 is compressed, the first end opening 25 of the fluid inflow channel 11, the central hole of the sealing member 20 and the channel inlet 2 of the microfluidic chip 1 just form a through channel, and the fluid does not leak from the contact surface between the microfluidic chip 1 and the sealing member 20 or the contact surface between the bottom surface of the groove 14 and the sealing member 20. In addition, fig. 7 may also show a schematic diagram of the first end opening of the fluid outflow channel and the channel outlet of the microfluidic chip 1. The method of securing the seal 20 with the annular groove 23 provides better protection against fluid leakage. Of course, the arrangement of the trough portions of FIG. 7 may be applied to other embodiments of parallel fluid distributors.

Fig. 8 shows a third embodiment of a parallel fluid dispenser 10 according to an embodiment of the invention.

In this embodiment, compared to the second embodiment of the parallel fluid dispenser, the pressure measuring device 17 is connected to a data line 24, and the data line 24 is used to transmit the pressure data read by the pressure measuring device 17 to a receiving end in real time, where the receiving end may be a computer or other device.

Likewise, the pressure measurement element of the first embodiment of the parallel fluid dispenser may also be connected to a data line to transmit pressure data to the receiving end in real time.

Claims

1. A parallel fluid dispenser, comprising:

the microfluidic chip is provided with a single inlet and a single outlet, and a flow limiting channel is arranged between the inlet and the outlet, or the microfluidic chip is provided with a single inlet and a plurality of outlets, and a flow limiting channel is arranged between the inlet and each outlet;

the pressure measuring elements are connected with the outlet of the microfluidic chip and are used for measuring and reading the pressure of the outlet of the microfluidic chip in real time;

the base comprises a base seat,

a slot having a size that is the same as the microfluidic chip, the microfluidic chip being placed within the slot,

a base fluid inflow channel and a base fluid outflow channel, wherein a first end opening of the base fluid inflow channel and a first end opening of the base fluid outflow channel are arranged in the groove, the first end opening of the base fluid inflow channel corresponds to an inlet position of the microfluidic chip, the first end opening of the base fluid outflow channel corresponds to an outlet position of the microfluidic chip, the second end opening of the base fluid inflow channel is arranged on one side of the base, and the second end opening of the base fluid outflow channel is arranged on one side of the base;

seals between the inlet of the microfluidic chip and the first end opening of the base fluid inflow channel, and between the outlet of the microfluidic chip and the first end opening of the base fluid outflow channel, the seals being annular rubber rings with central holes;

a fixture for compression of the microfluidic chip, seal and groove plane.

2. The parallel fluid dispenser of claim 1, wherein the parallel fluid dispenser provides a plurality of microfluidic chips with a single inlet and a single outlet of equal flow resistance.

3. The parallel fluid dispenser of claim 1, wherein the parallel fluid dispenser is provided with a microfluidic chip having a single inlet and a plurality of outlets, and wherein the flow resistance of each of the restricted flow channels between the single inlet and the plurality of outlets is equal.

4. The parallel fluid dispenser of any one of the preceding claims, wherein the microfluidic chip is made of glass, quartz, silicon dioxide, or metal.

5. The parallel fluid dispenser of any one of the preceding claims, wherein a groove is provided in the base for receiving and retaining the seal, the groove being sized to match the profile of the seal.

6. The parallel fluid distributor of claim 5, wherein the groove provided in the groove of the base is a cylindrical groove for placing and fixing the sealing member, the cylindrical groove has a diameter equal to the outer diameter of the sealing member, and the depth of the cylindrical groove is 1-20% smaller than the height of the sealing member.

7. The parallel fluid distributor of claim 5, wherein the groove is an annular groove disposed in the groove of the base, the annular groove is used for placing and fixing the sealing element, the width of the annular groove is equal to the annular diameter of the sealing element, and the depth of the annular groove is 1-20% smaller than the height of the sealing element.

8. The parallel fluid dispenser of any one of the preceding claims, wherein the fasteners are threaded cover plates and bolts, and the corresponding locations of the base plate have threaded holes, the cover plates and bolts compressing the microfluidic chip, seal and slot planes.

9. The parallel fluid dispenser of any one of the preceding claims, wherein a data line is connected to the pressure measurement element, the data line being configured to transmit pressure data.