CN114176837A - Valve clamping device and valve repair system - Google Patents

Abstract

The invention relates to a valve clamping device and a valve repair system, wherein the valve clamping device comprises a central shaft cylinder, a plurality of clamping arms and a plurality of sliding components, the plurality of clamping arms are wound on the periphery of the central shaft cylinder, one end of each clamping arm is rotatably connected with the central shaft cylinder, and the clamping arms are arranged to be unfolded or closed according to rotation; the sliding members are arranged in the central shaft barrel in a sliding mode along the axial direction, the sliding members are sequentially sleeved, and each sliding member is connected with at least one clamping arm through a pivoting mechanism, so that the clamping arms can rotate according to the sliding of the sliding members. The sliding components in the valve clamping device are sequentially sleeved and connected, so that the installation space in the central shaft cylinder is fully utilized, and the size of the valve clamping device is favorably reduced; each sliding component can independently slide and can drive at least one clamping arm connected with the sliding component to move, so that the clamping arms are independently closed to clamp the valve, the clamping inaccuracy caused by simultaneous clamping of a plurality of clamping arms is avoided, and the valve clamping effect is improved.

Description

Valve clamping device and valve repair system

Technical Field

The invention belongs to the technical field of medical instruments, and particularly relates to a valve clamping device and a valve repair system.

Background

The heart valve refers to a valve between an atrium and a ventricle or between the ventricle and an artery, wherein an atrioventricular valve comprises a mitral valve and a tricuspid valve, the mitral valve is a two-piece valve which is attached to the periphery of an atrioventricular opening of a left atrium and is connected with papillary muscles through chordae tendineae, the function of preventing blood in the left ventricle from flowing back to the left atrium is realized, mitral regurgitation is a series of pathophysiological changes caused by poor anastomosis of anterior and posterior leaflets of the mitral valve due to organic or functional changes of mitral valve leaflets and related structures, and blood flow can flow back from the left ventricle to the left atrium during the mitral valve regurgitation.

Surgical valve repair or replacement is considered as a standard treatment method for the diseases, however, the surgical operation has the defects of large trauma, obvious postoperative pain, slow recovery, high risk and the like, in recent years, the interventional therapy of the valvular heart disease is rapidly developed due to the advantages of small trauma, relative safety, good curative effect and the like, wherein the valve repair method developed according to the technical principle of the edge-to-edge suture of the surgical valve is high in safety, simple in technical principle and high in feasibility.

However, in the related art, the valve clamping device is mostly designed to clamp two valve leaflets by closing the two clamping arms at two sides simultaneously after the two valve leaflets are captured, and because the two valve leaflets of different operation individuals have different sizes and relative position states, when the two clamping arms are closed simultaneously, the two valve leaflets cannot be clamped simultaneously, so that the valve clamping device has the risk of only clamping one valve leaflet and being dislocated or even separated from the other valve leaflet, the clamping effect is poor, repeated clamping is needed, the operation is complicated, and the operation effect is affected.

Disclosure of Invention

The invention aims to at least solve the problem of poor clamping effect of a valve clamping device. The purpose is realized by the following technical scheme:

the present invention proposes, in a first aspect, a valve clip comprising:

a central shaft cylinder;

the clamping arms are wound on the periphery of the central shaft barrel, one end of each clamping arm is rotatably connected with the central shaft barrel, and the clamping arms are arranged to be opened or closed according to rotation;

the sliding members are arranged in the central shaft barrel in a sliding mode along the axial direction and are sequentially sleeved, and each sliding member is connected with at least one clamping arm through a pivoting mechanism, so that the clamping arms can rotate according to the sliding of the sliding members.

The valve clamping device provided by the embodiment of the invention has the following advantages:

in the embodiment of the invention, the plurality of sliding components are arranged in the central shaft cylinder, and the limited installation space in the central shaft cylinder is fully utilized in a sequential sleeving manner, so that the size of the valve clamping device is favorably reduced; each sliding component can realize independent sliding without mutual influence; each sliding component can drive at least one clamping arm connected with the sliding component to move, so that the clamping arms are independently closed to clamp the valve, the clamping inaccuracy caused by simultaneous clamping of a plurality of clamping arms is avoided, and meanwhile, the independent closing of the clamping arms reduces the difficulty of operation, thereby improving the clamping effect of the valve.

In addition, the valve clamping device provided by the embodiment of the invention can also have the following technical characteristics:

in some embodiments of the present invention, one end of the pivoting mechanism is fixedly connected to the sliding member, and the other end of the pivoting mechanism is rotatably connected to the clamping arm.

In some embodiments of the present invention, the pivoting mechanism includes a base and a linkage arm, the base is fixedly connected to the sliding member, one end of the linkage arm is connected to the base, and the other end of the linkage arm is rotatably connected to the clamping arm.

In some embodiments of the invention, the linkage arm is rotatably coupled to the base.

In some embodiments of the invention, the slide member extends from a distal end of the central shaft, and the base is attached to an end of the slide member extending from the central shaft.

In some embodiments of the invention, the plurality of slide members includes a slide bar and at least one slide barrel, the at least one slide barrel slidably disposed within the central shaft barrel and extending from a distal end of the central shaft barrel, the slide bar slidably disposed within an innermost slide barrel and extending from a distal end of the slide barrel.

In some embodiments of the invention, the valve binder further comprises a locking mechanism coupled to at least one of the sliding member, the pivoting mechanism, and the clip arms, the locking mechanism configured to at least limit deployment of the clip arms upon closure.

In some embodiments of the invention, the valve binder further comprises a catching member mounted between the central shaft barrel and the clamping arms, a side of the catching member facing the clamping arms being provided with barbs to catch a valve.

A second aspect of the invention provides a valve repair system comprising a delivery device and a valve binder as set forth in any of the above embodiments, the delivery device being detachably connectable to the valve binder for delivering the valve binder to a set position.

The valve repair system provided by the embodiment of the invention has the same advantages as the valve clamping device provided by any one of the embodiments, and the details are not repeated herein.

In some embodiments of the present invention, the conveying device comprises a plurality of driving members, each driving member being connected with one of the sliding members to drive the sliding members to slide.

Drawings

In the following, the drawings of the embodiments will be briefly described, and those skilled in the art can also derive other drawings from them without inventive effort.

FIG. 1 is a first schematic structural view of a valve clamp according to an embodiment of the present invention;

FIG. 2 is a front view of the valve binder shown in FIG. 1;

FIG. 3 is a second schematic structural view of a valve binder according to an embodiment of the invention;

FIG. 4 is a front view of the valve binder shown in FIG. 3;

FIG. 5 is a third schematic structural view of a valve binder according to an embodiment of the invention;

FIG. 6 is a schematic structural view of a valve repair system according to an embodiment of the present invention;

fig. 7 is a schematic cross-sectional view of a drive member coupled to a sliding member in a valve repair system according to an embodiment of the invention.

The reference symbols in the drawings denote the following:

1000. a valve repair system;

100. a valve clamp;

10. a central shaft cylinder; 11. a mounting seat;

20. clamping arms; 201. an avoidance groove; 202. connecting lugs; 21. a first clamp arm; 22. a second clamp arm;

30. a sliding member; 31. a slide bar; 32. a slide cylinder;

40. a pivoting mechanism; 41. a base; 411. a first base; 412. a second base; 42. a linkage arm; 421. a first linkage arm; 422. a second linkage arm;

51. a locking spring sheet; 511. a locking hole;

60. a capturing member;

710. a handle; 720. a sheath tube; 730. a bending adjusting mechanism; 741. a first drive member; 742. a second drive member.

Detailed Description

As described in the background art, for example, in a mitral valve repair operation, a valve clamping device closes two side clamping arms to clamp a valve simultaneously, and the inventor finds that, in an experimental process, since the valve is always in a moving state in the operation process, the operating requirements of an operator and the specific position precision requirements of the clamping arms are high when the two side clamping arms are closed to clamp valve leaflets at the same time, it is difficult to ensure that the two valve leaflets are accurately clamped at the same time, and the situation that one side clamping arm clamps in place and the other side clamping arm is staggered with the valve leaflets is very easy to occur, so that not only the two side clamping arms need to be unfolded to clamp the valve leaflets again, but also the valve leaflets are easily damaged by repeated clamping, and the operation effect is affected. In order to solve the problems, the invention provides a valve clamping device and a valve repair system. Taking mitral valve repair surgery as an example, when an operator clamps valve leaflets by using the valve clamping device provided by the invention, the operator can close one of the clamping arms to clamp one valve leaflet first, then finely adjust the angle or position of the valve clamping device relative to the other valve leaflet according to the conditions of different surgical individuals, close to and align with the other valve leaflet as far as possible and then clamp the valve leaflets, so that the operation difficulty is reduced, and the valve clamping device can clamp the valve leaflets quickly and accurately, thereby improving the clamping effect.

The terminology used herein, in connection with the appended drawings of embodiments of the invention, is for the purpose of describing particular example embodiments only and is not intended to be limiting of the invention, e.g., the terms "comprising", "including", "having", and the like, do not denote the presence of the stated features nor do they exclude the presence of other features; the terms "first", "second", and the like do not imply a sequence or order; the terms "inner", "outer", "above", "below" are used merely for convenience in describing the relationship of one feature to another feature shown in the drawings and do not indicate that they must have a particular orientation. In the field of interventional medical devices, the proximal end refers to the end closer to the operator, and the distal end refers to the end farther from the operator; axial refers to a direction parallel to the line connecting the center of the distal end and the center of the proximal end of the medical device in its natural state.

Referring to fig. 1 to 5, in a first aspect of the present invention, a valve clamping device 100 is provided, the valve clamping device 100 includes a central shaft 10, a plurality of clamping arms 20 and a plurality of sliding members 30, the plurality of clamping arms 20 are wound around the periphery of the central shaft 10, one end of each clamping arm 20 is rotatably connected to the central shaft 10, and the clamping arms 20 are configured to be opened or closed according to rotation; the plurality of sliding members 30 are slidably disposed in the central shaft tube 10 along the axial direction, the plurality of sliding members 30 are sequentially sleeved, and each sliding member 30 is connected with at least one clamping arm 20 through a pivoting mechanism 40, so that the clamping arm 20 rotates according to the sliding of the sliding member 30.

The valve clip 100 of the present embodiment can be used as a margin-to-margin repair implant in the field of interventional therapy for heart diseases, and the valve clip 100 of the present embodiment can reach a designated location through a minimally invasive access and a blood vessel through a body surface, so as to achieve repair therapy for heart valves (including but not limited to mitral valve, tricuspid valve, aortic valve, and pulmonary valve). It can be understood that, since the valve clamping device 100 needs to be implanted inside the heart of the patient, especially in the way of minimally invasive access through the body surface and blood vessel introduction, the volume of the valve clamping device 100 is strictly limited, the present embodiment, by disposing the plurality of sliding members 30 in the central shaft cylinder 10 in a sequentially sleeved manner, meets the requirement of limited volume of the valve clamping device 100, not only fully utilizes the limited installation space in the central shaft cylinder 10, but also ensures that each sliding member 30 can realize independent sliding and does not influence each other, on this basis, in the present embodiment, the plurality of sliding members 30 are utilized to respectively drive the clamping arms 20 to rotate, so that the clamping arms 20 can be independently closed to clamp the valve, thereby facilitating the operator to finely adjust the angle or position of the valve clamping device 100 after clamping the valve leaflets on one side, realizing accurate clamping of the valves on the other sides, and avoiding the problems of great difficulty and inaccurate clamping operation of the plurality of clamping arms 20 at the same time, reduces the difficulty of operation and solves the problem of poor clamping effect of the valve clamping device 100.

As shown in fig. 1 and 3, in the valve clip 100 provided in the present embodiment, the central shaft cylinder 10 is located at a middle position of the valve clip 100, and it is understood that the central shaft cylinder 10 has a cavity therein, and the central shaft cylinder 10 is used for providing an installation space for the sliding member 30 so that the sliding member 30 can slide therein; one end of the clamping arm 20 is rotatably connected to the central shaft 10, and when the sliding member 30 is interlocked with the clamping arm 20, the clamping arm 20 can rotate around the connection with the central shaft 10. The central shaft tube 10 in the present embodiment is configured as a tube structure, and may be configured as a tube structure, for example, a square tube structure, or a tube structure with other shapes according to actual requirements.

The valve clamping device 100 provided in this embodiment includes a plurality of clamping arms 20, and the clamping arms 20 are used for clamping a valve, it should be noted that, in this embodiment, the number of the clamping arms 20 may be set to two, or may also be set to more than two, for example, if the valve clamping device 100 is applied to mitral valve repair treatment, the number of the clamping arms 20 may be set to two accordingly, if the valve clamping device 100 is applied to tricuspid valve repair treatment, the number of the clamping arms 20 may be set to three accordingly, the number of the clamping arms 20 in this embodiment is not specifically limited, and may be set according to actual requirements. On the basis of the above embodiment, the plurality of clamping arms 20 are arranged around the central shaft cylinder 10, and may be arranged at equal intervals or at unequal intervals, for example, when the number of the clamping arms 20 is two, the two clamping arms 20 may be arranged symmetrically with respect to the central shaft cylinder 10.

In this embodiment, the shape of the clamping arm 20 may be a long plate, for example, a flat plate, or an arc plate, and the two clamping arms 20 may be the same or different in structure; one end of each clamping arm 20 is rotatably connected to the central shaft tube 10, for example, as shown in fig. 1 and fig. 3, taking the clamping arm 20 as an arc-shaped plate as an example, the distal end of the clamping arm 20 is rotatably connected to the central shaft tube 10, and the inner arc surface of the clamping arm 20 faces the central shaft tube 10, when the number of the clamping arms 20 is two, the two clamping arms 20 are symmetrically arranged on two sides of the central shaft tube 10, and the two clamping arms 20 are in a clasping state after being closed, so as to facilitate clamping the valve. Further, as shown in fig. 3, an avoiding groove 201 is formed at a portion of the clamping arm 20 close to the distal end, two engaging lugs 202 are extended from the distal end of the clamping arm 20, the two engaging lugs 202 are respectively located at two sides of the avoiding groove 201 and extend to two opposite sides of the outer side wall of the central shaft cylinder 10, so as to be rotatably connected with the central shaft cylinder 10, illustratively, the two engaging lugs 202 can be rotatably connected through a rotating shaft, the rotating shaft is installed on the central shaft cylinder 10 and passes through a connecting hole formed in the engaging lug 202, so that the clamping arm 20 can rotate around the rotating shaft.

With reference to fig. 1 to fig. 5, the number of the clamping arms 20 is two, and the two clamping arms 20 are respectively a first clamping arm 21 and a second clamping arm 22, and the engaging lugs 202 of the first clamping arm 21 and the second clamping arm 22 located on the same side can be matched with the same rotating shaft, on this basis, the two engaging lugs 202 of the first clamping arm 21 can be located on the outer side or the inner side of the two engaging lugs 202 of the second clamping arm 22 at the same time, or one engaging lug 202 of the first clamping arm 21 is located on the outer side of the engaging lug 202 of the second clamping arm 22, and the other engaging lug 202 of the first clamping arm 21 is located on the inner side of the engaging lug 202 of the second clamping arm 22 on the same side, so as to ensure the reliability of the connection between the first clamping arm 21 and the second clamping arm 22 and the central shaft barrel 10, which is not specifically limited in this embodiment.

In the valve clamping device 100 provided in this embodiment, the sliding member 30 is configured to drive the clamping arms 20 to rotate through sliding, in this embodiment, the number of the sliding member 30 may be two, or may be more than two, and each sliding member 30 may be coupled with one clamping arm 20, or may be coupled with a plurality of clamping arms 20, and it can be understood that, when one sliding member 30 is connected with a plurality of clamping arms 20, the sliding member 30 can drive the connected plurality of clamping arms 20 to rotate and open at the same time. Illustratively, the number of the slide members 30 is set to two, and the number of the clamp arms 20 is set to three, whereby one of the slide members 30 connects one of the clamp arms 20, and the other slide member 30 connects two of the clamp arms 20; when the number of the slide members 30 is equal to the number of the clip arms 20, one clip arm 20 is connected to each slide member 30.

With reference to fig. 1 to 5, on the basis of the above embodiment, when the number of the clamping arms 20 is two, the number of the sliding members 30 may also be two, and on this basis, the two sliding members 30 are both disposed in the central shaft tube 10, and the two sliding members 30 are, for example, the first sliding member 30 and the second sliding member 30, respectively, and the first sliding member 30 is sleeved outside the second sliding member 30, and the first sliding member 30 is located between the central shaft tube 10 and the second sliding member 30, in this embodiment, the matching manners between the central shaft tube 10 and the first sliding member 30 and between the first sliding member 30 and the second sliding member 30 are both set to be clearance fit, so that the first sliding member 30 and the second sliding member 30 slide relative to the central shaft tube 10.

On the basis of the above embodiment, as shown in fig. 5, each sliding member 30 is connected to the clamping arm 20 through a pivoting mechanism 40, that is, at least a part of the sliding member 30 is exposed outside the central shaft tube 10, so that the pivoting mechanism 40 can be connected to the exposed part. In an alternative embodiment, the wall of the central shaft 10 may be opened with a plurality of windows, and the windows have a certain length along the axial direction, so that one end of the pivot mechanism 40 can extend into the windows and be connected with the sliding member 30, and when the sliding member 30 slides, the pivot mechanism 40 moves within a range defined by the windows, and then drives the clamping arms 20 to rotate. In an alternative embodiment, as shown in fig. 2 and 4, the distal end of the central shaft 10 has an opening communicating with the internal cavity, and the sliding member 30 extends from the opening, i.e., the sliding member 30 extends from the distal end of the central shaft 10. in this regard, one end of the pivoting mechanism 40 is connected to the portion of the sliding member 30 from which the sliding member 30 extends, and when the sliding member 30 slides, the pivoting mechanism 40 moves along with it, thereby rotating the clip arms 20.

On the basis of the above embodiment, the pivoting mechanism 40 is respectively connected to the sliding member 30 and the clamping arm 20, and the clamping arm 20 is driven to rotate around the connection with the central shaft tube 10 according to the sliding of the sliding member 30, and the structure of the pivoting mechanism 40 will be described in detail below. With continued reference to fig. 1-5, in some embodiments of the present invention, one end of the pivoting mechanism 40 is fixedly connected to the sliding member 30, and the other end is rotatably connected to the clamping arm 20, it can be understood that when the sliding member 30 slides axially and distally, the pivoting mechanism 40 moves distally accordingly, and drives the clamping arm 20 rotatably connected thereto to rotate in a direction away from the central shaft 10, i.e., drives the clamping arm 20 to unfold; when the sliding member 30 slides axially and proximally, the pivoting mechanism 40 moves proximally, and drives the clip arms 20 connected to rotate in a direction approaching the central shaft 10, i.e., drives the clip arms 20 to close.

In some embodiments of the present invention, the pivoting mechanism 40 includes a base 41 and a linkage arm 42, the base 41 is fixedly connected to the sliding member 30, and the fixed connection may be a manner that the base 41 is integrally formed with the sliding member 30, or a manner that the base is welded, which is not limited in this embodiment. The position of the base 41 connected to the sliding member 30 may be set according to the structures of the sliding member 30 and the central shaft cylinder 10, for example, in some embodiments of the present invention, the sliding member 30 extends from the distal end of the central shaft cylinder 10, the base 41 may be connected to the portion of the sliding member 30 extending from the central shaft cylinder 10, and further, the base 41 is connected to the end of the sliding member 30, that is, the base 41 is connected to the distal end of the sliding member 30, so that the moving range of the base 41 is the same as the moving range of the distal end of the sliding member 30, thereby expanding the moving range of the base 41 and further expanding the opening and closing range of the clip arms 20. On this basis, the one end of linkage arm 42 is connected with base 41, and the other end of linkage arm 42 rotates with arm lock 20 and is connected, and from this, when base 41 along with sliding member 30 along the axial slip, linkage arm 42 rotates between base 41 and arm lock 20, and then drives arm lock 20 and rotate, and linkage arm 42 has the multiple with base 41's connected mode in this embodiment, can set up to rotate and connect, also can set up to elastic connection, and concrete connected mode can set up according to actual demand.

In an alternative embodiment, the linkage arm 42 and the base 41 may be configured as an integral elastic structure, such as a shape memory alloy, or the linkage arm 42 and the base 41 are connected through elastic components, such as a spring sheet and a torsion spring, and it can be understood that when the base 41 moves in the axial direction, the elastic component connected between the base 41 and the linkage arm 42 is elastically deformed, so that the linkage arm 42 can rotate within a certain range, and further the clamping arm 20 is driven to rotate. In another alternative embodiment, the linkage arm 42 is rotatably connected to the base 41, and the linkage arm 42 and the base 41 may be hinged or connected by a hinge.

As shown in fig. 3 and 5, one side of the base 41, which is away from the sliding member 30, is rotatably connected to the linkage arm 42 through a rotation shaft, specifically, a first connection hole may be penetratingly formed in the base 41, two connection portions may be extended from one end of the linkage arm 42, which is close to the base 41, the connection portions may be specifically configured as connection rods or connection plates, a second connection hole is penetratingly formed in the connection portions, the two connection portions are respectively located at two sides of the base 41, and the rotation shaft is penetratingly formed in the first connection hole and the second connection hole, so that the linkage arm 42 is rotatably connected to the base 41; or, the base 41 is welded or integrally provided with a rotating shaft, the connecting part is provided with a connecting hole in a penetrating way, and the connecting hole is matched with the rotating shaft and can rotate around the rotating shaft, so that the assembly is convenient, and the reliability of the connection between the base 41 and the linkage arm 42 is ensured.

As shown in fig. 3 and 5, one end of the linkage arm 42, which is far away from the base 41, is rotatably connected to the clamping arm 20, according to the above embodiment, the distal end of the clamping arm 20 is rotatably connected to the central shaft barrel 10, in this embodiment, the linkage arm 42 is connected to the middle portion of the clamping arm 20, so that the linkage arm 42 can apply a pulling force or a pushing force to the clamping arm 20 when rotating, and further drive the clamping arm 20 to rotate, thereby realizing the unfolding or closing. The linkage arm 42 can be connected with the clamping arm 20 through a rotating shaft or hinged through a hinge, an avoiding groove 201 is formed in the part, close to the far end, of the clamping arm 20 in the embodiment, a mounting hole can be formed in the groove wall of the avoiding groove 201, a mounting shaft can be arranged at one end, away from the base 41, of the linkage arm 42, the end extends into the avoiding groove 201 and enables the mounting shaft to be matched with the mounting hole, and therefore the linkage arm 42 is connected with the clamping arm 20 in a rotating mode.

In the present embodiment, the sliding members 30 are sequentially sleeved to reduce the overall volume of the valve clamping device 100 by saving the installation space, so as to facilitate the implantation of the valve clamping device 100 at the valve position, please refer to fig. 2 to 5, in some embodiments of the present invention, the sliding members 30 include a sliding rod 31 and at least one sliding barrel 32, the at least one sliding barrel 32 is slidably disposed in the central barrel 10 and extends from the distal end of the central barrel 10, the sliding rod 31 is slidably disposed in the innermost sliding barrel 32 and extends from the distal end of the sliding barrel 32, the sliding rod 31 and the sliding barrel 32 are respectively connected to the at least one clamping arm 20 through a pivoting mechanism 40, so as to respectively drive the at least one clamping arm 20 to rotate to open and close, it should be noted that the inner side in the present embodiment refers to the side close to the central barrel 10.

Illustratively, when the number of the clamping arms 20 and the sliding members 30 is two, the two sliding members 30 include a sliding rod 31 and a sliding barrel 32, the sliding rod 31 and the sliding barrel 32 are both disposed in the central shaft barrel 10, and the sliding barrel 32 is sleeved outside the sliding rod 31, the sliding rod 31 and the sliding barrel 32 are respectively connected with one clamping arm 20 through a pivoting mechanism 40, according to the above embodiment, the pivoting mechanism 40 includes a base 41 and a linkage arm 42, as shown in fig. 3 and 4, the sliding barrel 32 is connected with the first clamping arm 21 through a first pivoting mechanism, the first pivoting mechanism includes a first base 411 and a first linkage arm 421, the sliding rod 31 is connected with the second clamping arm 22 through a second pivoting mechanism, the second pivoting mechanism includes a second base 412 and a second linkage arm 422, on the basis, the distal end of the sliding barrel 32 extends from the distal end of the central shaft barrel 10, the first base 411 is fixedly connected with the distal end of the sliding barrel 32, the far end of the first linkage arm 421 is rotatably connected to the first base 411 through a rotating shaft, the near end of the first linkage arm 421 is rotatably connected to the first clamping arm 21 through a rotating shaft, and the far end of the first clamping arm 21 is rotatably connected to the central shaft barrel 10 through a rotating shaft; the far end of the slide bar 31 extends from the far end of the slide cylinder 32, the second base 412 is fixedly connected with the far end of the slide bar 31, the far end of the second linkage arm 422 is rotatably connected to the second base 412 through a rotating shaft, the near end of the second linkage arm 422 is rotatably connected to the second clamping arm 22 through a rotating shaft, and the far end of the second clamping arm 22 is rotatably connected to the central shaft cylinder 10 through a rotating shaft. Wherein the first base 411 is located between the second base 412 and the central shaft tube 10, it can be understood that when there are a plurality of sliding members 30, the base 41 of the pivoting mechanism 40 connected to the sliding rod 31 is located at the outermost side of all the bases 41, which is the side far away from the central shaft tube 10 in this embodiment, so as to ensure that all the sliding members 30 can individually slide toward the proximal end, thereby bringing the corresponding clipping arms 20 to close.

Further, referring to fig. 1 to 5, in some embodiments of the present invention, the valve clamping device 100 further includes a locking mechanism, in this embodiment, the locking mechanism is connected to one or more of the sliding member 30, the pivoting mechanism 40 and the clamping arms 20, and the locking mechanism can at least limit the rotation and the expansion of the clamping arms 20 after the clamping arms 20 are closed, it can be understood that the locking mechanism in this embodiment can be configured to only limit the rotation and the expansion of the clamping arms 20 after the clamping arms are closed, or can be configured to limit the expansion of the clamping arms 20 and the closing of the clamping arms 20, that is, the locking mechanism can limit the rotation of the clamping arms 20 under a set condition. Illustratively, the locking mechanism serves to limit the deployment of the clip arms 20 after the clip arms 20 are closed, thereby leaving the valve binder 100 in a state of clamping the valve inside the patient.

In an alternative embodiment, the locking mechanism may be mounted on the central shaft tube 10 and connected to the sliding member 30, so as to limit the rotation of the clamping arm 20 by limiting the sliding of the sliding member 30, for example, please refer to fig. 1 to 5, the locking mechanism includes a control wire (not shown in the figure) and a locking elastic sheet 51, the locking elastic sheet 51 is provided with a locking hole 511, the sliding member 30 is inserted into the locking hole 511 and can abut against an inner wall of the locking hole 511, the locking elastic sheet 51 is connected to the control wire and can be elastically deformed by the pulling of the control wire, thereby, the locking elastic sheet 51 keeps an inclined state when not stressed, so as to abut against and clamp the sliding member 30, and the control wire pulls the locking elastic sheet 51 to rotate to a horizontal state to release the abutment. In addition, the mounting seat 11 is arranged at a position of the central shaft tube 10 close to the distal end, and one end of the locking elastic sheet 51 is connected with the mounting seat 11, it can be understood that, due to the small size of the central shaft tube 10, the mounting seat 11 is arranged in the embodiment, so that the locking elastic sheet 51 is conveniently connected with the central shaft tube 10, and the reliability of connection between the locking elastic sheet 51 and the central shaft tube 10 is improved.

It is understood that one or more locking mechanisms may be provided in the present embodiment, and on the basis that a plurality of sliding members 30 are sequentially nested in the above embodiment, the locking mechanism may cooperate with the innermost sliding member 30, so as to prevent all sliding members 30 from sliding. In another alternative embodiment, a locking mechanism can be connected to the pivoting mechanism 40 or the clamping arm 20 to limit the rotation of the clamping arm 20 by limiting the rotation of the pivoting mechanism 40. for example, the locking mechanism can include a control wire and a locking coil, and the control wire can be used to pull the linkage arm 42 of the locking coil locking pivoting mechanism 40 or the clamping arm 20 to limit the rotation of the clamping arm 20. The structure of the locking mechanism is not particularly limited in this embodiment, and may be set according to actual conditions.

Further, as shown in fig. 1 to 5, in some embodiments of the present invention, the valve binder 100 further includes a catching member 60, the catching member 60 is installed between the central shaft cylinder 10 and the clamping arms 20, a side of the catching member 60 facing the clamping arms 20 is provided with a barb for catching the valve, accordingly, the valve binder 100 further includes a control wire, such as a suture, a nylon wire or a metal wire, connected to the catching member 60, the control wire is used for driving the catching member 60 to rotate, thereby, during the process of clamping the valve by the valve binder 100, the valve can be caught by the catching member 60 first and then clamped by the clamping arms 20, exemplarily, the catching member 60 can be configured as a catching elastic piece formed by processing a shape memory alloy, such as nitinol, and the catching elastic piece includes a plurality of sub elastic pieces, such as two sub elastic pieces respectively located at two sides of the central shaft cylinder 10, two bullet pieces can set up to integrated into one piece structure, and have the contained angle of settlement between the two, and the control silk thread can be provided with one to two sub-shell fragments of simultaneous control, perhaps the control silk thread can be provided with many, and every control silk thread is connected and is controlled a sub-shell fragment. The embodiment is convenient for the catching component 60 to catch the valve when contacting with the valve by arranging the barb on the catching component 60, thereby improving the accuracy of clamping the subsequent clamping arms 20.

Referring to fig. 6, a valve repair system 1000 is provided according to an embodiment of the second aspect of the present invention, the valve repair system 1000 includes a delivery device and the valve clip 100 according to any of the above embodiments, the delivery device is detachably connected to the valve clip 100 to deliver the valve clip 100 to a set position. The delivery device in this embodiment comprises a handle 710, a sheath assembly and a connecting mechanism, wherein the sheath assembly comprises a bending adjusting mechanism 730 and a plurality of sheath 720 which are sequentially sleeved, the handle 710 is connected with the sheath assembly and can control part or all of the sheath 720 in the sheath assembly to reach a set position in a patient body, the bending adjusting mechanism 730 can control part or all of the sheath 720 in the sheath assembly to bend at the set position, and a control member of a locking mechanism in the valve clamp 100 can be connected to the handle 710, so that an operator can operate the control member through the handle 710; the attachment mechanism is attached to the distal end of the innermost one of the sheaths 720 and is removably attached to the valve clip 100, whereby, after the valve clip 100 is delivered to the set position, the valve clip 100 adjusts in position according to the bending and movement of the sheath 720, and after the valve clip 100 clamps and locks, the attachment mechanism disengages from the valve clip 100, leaving the valve clip 100 in the patient.

Further, referring to fig. 7, in some embodiments of the present invention, the conveying device includes a plurality of driving members, each driving member is connected to one sliding member 30 to drive the sliding member 30 to slide, the number of the driving members in this embodiment is set according to the number of the sliding members 30, and exemplarily, when the sliding members 30 are set to be two, the driving members are also set to be two, and the two driving members do not affect each other. According to the above embodiment, the innermost sheath 720 of the sheath assembly is provided with a channel, the driving member is inserted into the channel, and the distal end of the driving member is extended from the distal end of the sheath 720 and then matched with the sliding member 30 of the valve clamp 100, so that an operator can pull or push the driving member to pull or push the sliding member 30, thereby sliding the sliding member 30 in the axial direction.

Taking two sliding members 30 as an example, as shown in fig. 7, the two sliding members 30 include a sliding rod 31 and a sliding cylinder 32, in an alternative embodiment, a blind hole is formed at one end of the sliding rod 31 close to the conveying device, a first internal thread is formed in the blind hole, a first driving member 741 matched with the sliding rod 31 can be a metal wire, and a first external thread matched with the first internal thread is formed on an outer wall of the first driving member 741 close to the distal end, so that the distal end of the first driving member 741 is connected with the sliding rod 31; the inner wall of the slide cylinder 32 near the delivery device is provided with a second internal thread, the second driving member 742 engaged with the slide cylinder 32 may be provided as a metal tube, such as a shape memory alloy tube or the like that can be bent, and the outer wall of the second driving member 742 is provided with a second external thread engaged with the second internal thread, whereby the distal end of the second driving member 742 is connected with the slide cylinder 32. The proximal ends of the first and second drive members 741, 742 may be coupled to the handle 710, and an operator may control the movement and rotation of the first and second drive members 741, 742 via the handle 710. It can be understood that when the slide rod 31 needs to move axially, the operator can move the first driving member 741 through the handle 710, when the slide cylinder 32 needs to move axially, the operator can move the second driving member 742 through the handle 710, and when the delivery device needs to be detached from the valve clamp 100, the operator can rotate the first driving member 741 and the second driving member 742 in sequence through the handle 710, and withdraw the first driving member 741 and the second driving member 742 after the screw-thread engagement is released.

Based on the above embodiments, for example, taking two sliding members 30 in the valve clip 100 including one sliding bar 31 and one sliding cylinder 32 as an example, the operation method of the valve repair system 1000 according to the present embodiment is as follows: an operator operates the handle 710 to enable the sheath tube assembly and the valve clamping device 100 connected to the sheath tube 720 to reach a set position of a mitral valve through a body surface minimally invasive access and a blood vessel according to a set step, and after the locking of the locking mechanism is released, the handle 710 is firstly utilized to push the first driving member 741 and the second driving member 742, so that the sliding rod 31 and the sliding cylinder 32 move towards the far end, and the two clamping arms 20 are respectively unfolded; after the position of the valve clamping device 100 is adjusted to align with the portion of the mitral valve to be clamped, the valve at one side of the clamping arms 20 connected to the sliding cylinder 32 is first captured by the sub-spring at one side of the capturing member 60, the sliding cylinder 32 is moved proximally by pulling the second driving member 742 by the handle 710, so that the clamping arms 20 connected to the sliding cylinder 32 are closed to clamp the valve at the side, the valve at one side of the clamping arms 20 connected to the sliding rod 31 is captured by the sub-spring at the other side of the capturing member 60, the sliding rod 31 is moved proximally by pulling the first driving member 741 by the handle 710, so that the clamping arms 20 connected to the sliding rod 31 are closed to clamp the valve at the side, and finally the locking mechanism is used to lock the first driving member 741 and the sliding rod 31, release the second driving member 742 and the sliding cylinder 32, release the connecting mechanism and the valve clamping device 100, withdraw the first driving member 741, the second driving member 742 and the sheath assembly, leaving the valve clip 100 in a patient's body in a state in which it is clipped to the valve.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are also included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims (10)

1. A valve clip, comprising:

a central shaft cylinder;

the clamping arms are wound on the periphery of the central shaft barrel, one end of each clamping arm is rotatably connected with the central shaft barrel, and the clamping arms are arranged to be opened or closed according to rotation;

the sliding members are arranged in the central shaft barrel in a sliding mode along the axial direction and are sequentially sleeved, and each sliding member is connected with at least one clamping arm through a pivoting mechanism, so that the clamping arms can rotate according to the sliding of the sliding members.

2. The valve binder of claim 1, wherein one end of the pivot mechanism is fixedly connected to the sliding member and the other end of the pivot mechanism is pivotally connected to the clamp arm.

3. The valve binder of claim 2, wherein the pivoting mechanism comprises a base and a linkage arm, the base is fixedly connected with the sliding member, one end of the linkage arm is connected with the base, and the other end of the linkage arm is rotatably connected with the clamping arm.

4. The valve clip of claim 3 wherein the linkage arm is rotationally coupled to the base.

5. The valve holder of claim 3, wherein the sliding member extends from a distal end of the central shaft, the base being attached to an end of the sliding member extending from the central shaft.

6. The valve binder of claim 5, wherein the plurality of sliding members comprise at least one sliding bar slidably disposed within and extending from a distal end of the central shaft and at least one sliding barrel slidably disposed within and extending from a distal end of an innermost sliding barrel.

7. The valve binder of any one of claims 1 to 6, further comprising a catching member mounted between the central shaft barrel and the clamping arms, a side of the catching member facing the clamping arms being provided with barbs to catch a valve.

8. The valve binder of any one of claims 1 to 6, further comprising a locking mechanism coupled to at least one of the slide member, the pivot mechanism, and the clip arms, the locking mechanism configured to at least limit deployment of the clip arms upon closure.

9. A valve repair system, comprising:

a valve binder according to any one of claims 1 to 8;

the delivery device is detachably connected with the valve clamping device so as to deliver the valve clamping device to a set position.

10. The valve repair system of claim 9, wherein the delivery device includes a plurality of actuation members, each actuation member coupled to one of the sliding members to actuate the sliding members to slide.

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