CN114129471B - Suspension thickening composition and application thereof - Google Patents
Suspension thickening composition and application thereof Download PDFInfo
- Publication number
- CN114129471B CN114129471B CN202111481629.9A CN202111481629A CN114129471B CN 114129471 B CN114129471 B CN 114129471B CN 202111481629 A CN202111481629 A CN 202111481629A CN 114129471 B CN114129471 B CN 114129471B
- Authority
- CN
- China
- Prior art keywords
- suspension
- thickening composition
- acid
- gamma
- acrylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/88—Polyamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/48—Thickener, Thickening system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/594—Mixtures of polymers
Abstract
The invention discloses a suspension thickening composition and application thereof, wherein the active ingredients of the suspension thickening composition are acrylic acid (esters)/C10-30 alkanol acrylate cross-linked polymer, hyaluronic acid or salt thereof and gamma-polyglutamic acid. The invention firstly proposes that the suspension stability of the acrylic acid (esters)/C10-30 alkanol acrylate crosslinked polymer to the grease component is improved by compounding the acrylic acid (esters)/C10-30 alkanol acrylate crosslinked polymer, hyaluronic acid or salt thereof and gamma-polyglutamic acid, and the obtained composition can keep better suspension stability under long-term storage and high-speed centrifugation, and has smaller thickening effect change. The composition still has good suspension thickening effect in cosmetics, can suspend and stabilize high-content oil phase, can reduce the dosage of surfactant in an emulsion system, and has good application prospect.
Description
Technical Field
The invention relates to a composition with stable suspension dispersion oil phase and thickening effect, and also relates to application of the composition in cosmetics, belonging to the technical field of cosmetics.
Background
The acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer is an auxiliary material commonly used in cosmetics, mainly a high molecular weight polyacrylic acid polymer, which contains a small amount of lipophilic parts and a large amount of hydrophilic parts, can disperse oil and emulsify suspended small oil drops, and ensures that the oil components are in a stable suspension state in an aqueous system. And the acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer has lower toxicity and higher efficiency compared with a surfactant, and can meet the requirements of thickening or gelation of cosmetics as an effective water-based thickener.
However, in practical use, it has been found that a emulsion prepared by crosslinking a polymer of acrylic acid (esters) and a C10-30 alkanol acrylate alone has a phenomenon of water delamination when stored at high temperature or for a long period of time and is in a state of being slightly jelly-like, and thus improvement of stability thereof has been a problem to be solved.
Disclosure of Invention
Aiming at the defects of the prior acrylic acid (esters)/C10-30 alkanol acrylate cross-linked polymer in cosmetics, the invention provides a suspension thickening composition which is prepared by compounding hyaluronic acid or salt thereof and gamma-polyglutamic acid with the acrylic acid (esters)/C10-30 alkanol acrylate cross-linked polymer, and surprisingly discovers that the suspension thickening composition has good suspension stability, high-temperature stability and long-term stability on an oil phase.
A suspension thickening composition comprises acrylic acid (esters)/C10-30 alkanol acrylate cross-linked polymer, hyaluronic acid or its salt and gamma-polyglutamic acid as effective components. The composition can not obviously reduce the thickening effect of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer through the synergistic effect of the active ingredients, can well suspend and stabilize the grease components in the water phase, has good high-temperature stability and long-term stability, and can not generate the appearance of jelly emulsion due to long storage time.
Further, in the suspension thickening composition, the following active ingredients are used in parts by weight: the acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer is 0.1-0.5 part, hyaluronic acid or salt thereof is 0.005-0.02 part, and gamma-polyglutamic acid is 0.005-0.02 part.
Preferably, in the suspension thickening composition, the following active ingredients are used in parts by weight: the acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer is 0.2-0.4 part, hyaluronic acid or salt thereof is 0.005-0.01 part, and gamma-polyglutamic acid is 0.005-0.01 part.
Further, the molecular weight of the hyaluronic acid or the salt thereof is 150-200 Da, and in the molecular weight range, the effect is better. The hyaluronate is a soluble salt of hyaluronic acid, preferably sodium hyaluronate, magnesium hyaluronate, zinc hyaluronate or potassium hyaluronate, etc.
Furthermore, the suspension thickening composition is simple to prepare, and the suspension thickening composition can be obtained by physically and uniformly mixing the components.
Furthermore, the invention also provides application of the suspension thickening composition in cosmetics. It can be used as thickener for cosmetics and oil phase suspension stabilizer.
Further, the invention also provides a cosmetic, which comprises the suspension thickening composition.
Further, the content of acrylic acid (esters)/C10-30 alkanol acrylate cross-linked polymer in the suspension thickening composition is 0.1-0.5wt%, preferably 0.2-0.4wt% in the cosmetic. The content of hyaluronic acid or its salt in the suspension thickening composition is 0.005-0.02wt%, preferably 0.005-0.01wt% in the cosmetic. The content of gamma-polyglutamic acid in the suspension thickening composition in the cosmetic is 0.005-0.02wt%, preferably 0.005-0.01wt%.
Further, the cosmetic also comprises an alkaline agent, wherein the alkaline agent is used for neutralizing the suspension thickening composition and comprises sodium hydroxide, aminomethylpropanol, arginine and the like.
Further, the cosmetic may further include a carrier, which may be an aqueous carrier, such as water, including distilled water and deionized water.
Further, the cosmetic also comprises an oil phase, and the content of the oil phase is less than 50wt%, preferably less than or equal to 45wt%.
Further, the cosmetic includes, but is not limited to, skin care products such as cream, milky lotion, cream, etc.
Further, when the suspension thickening composition is used for preparing cosmetics, the acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, hyaluronic acid or salt thereof and gamma-polyglutamic acid are dispersed into a carrier (such as water) and uniformly stirred, and then neutralized with an alkaline agent, thereby obtaining cosmetics containing the suspension thickening composition.
The invention has the following beneficial effects:
1. the invention firstly proposes that the suspension stability of the acrylic acid (esters)/C10-30 alkanol acrylate crosslinked polymer to the grease component is improved by compounding the acrylic acid (esters)/C10-30 alkanol acrylate crosslinked polymer, hyaluronic acid or salt thereof and gamma-polyglutamic acid, and the obtained composition can keep better suspension stability of the grease component under high-temperature and long-term storage and high-speed centrifugation.
2. The thickening effect of the system is reduced when the acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer is used as a high molecular polymer and is mixed with single hyaluronic acid or salt thereof or gamma-polyglutamic acid, and the thickening effect of the acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, the hyaluronic acid or salt thereof and the gamma-polyglutamic acid is hardly reduced while the suspension stability of grease is improved.
3. The composition can be added into cosmetics, still has good suspension thickening effect in the cosmetics, can suspend and stabilize high-content oil phase, improves the appearance of jelly emulsion which is stored for a long time when the acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer is singly applied, and has good application prospect.
Drawings
Fig. 1 is an optical micrograph (40 times) of the gel milk prepared in example 1 after storage at 55 ℃ for 5 days.
Detailed Description
In order to better illustrate the technical scheme and advantages of the present invention, the present invention will be further explained and illustrated with reference to the following specific examples. It should be noted that the process parameters, process steps, etc. not specifically described in the present invention are all carried out according to the technical means conventional in the art, and all percentages and parts are by weight.
In the examples described below, the acrylic/C10-30 alkanol acrylate cross-linked polymers used were obtained by commercial means, sodium hyaluronate and gamma polyglutamic acid from Hua Xi Biotech Co.
Example 1
A suspension thickening composition consists of the following components in parts by weight: 0.25 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.01 part of sodium hyaluronate, 0.01 part of gamma-polyglutamic acid, and the molecular weight of the sodium hyaluronate is 150-200 ten thousand Da. Mixing the above materials.
Example 2
A suspension thickening composition consists of the following components in parts by weight: 0.1 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.01 part of sodium hyaluronate, 0.01 part of gamma-polyglutamic acid, and the molecular weight of the sodium hyaluronate is 150-200 ten thousand Da. Mixing the above materials.
Example 3
A suspension thickening composition consists of the following components in parts by weight: 0.4 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.01 part of sodium hyaluronate, 0.01 part of gamma-polyglutamic acid, and the molecular weight of the sodium hyaluronate is 150-200 ten thousand Da. Mixing the above materials.
Example 4
A suspension thickening composition consists of the following components in parts by weight: 0.5 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.01 part of sodium hyaluronate, 0.01 part of gamma-polyglutamic acid, and the molecular weight of the sodium hyaluronate is 150-200 ten thousand Da. Mixing the above materials.
Example 5
A suspension thickening composition consists of the following components in parts by weight: 0.25 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.005 part of sodium hyaluronate, 0.02 part of gamma-polyglutamic acid, and the molecular weight of the sodium hyaluronate is 150-200 ten thousand Da. Mixing the above materials.
Example 6
A suspension thickening composition consists of the following components in parts by weight: 0.25 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.005 part of sodium hyaluronate, 0.01 part of gamma-polyglutamic acid, and the molecular weight of the sodium hyaluronate is 150-200 ten thousand Da. Mixing the above materials.
Example 7
A suspension thickening composition consists of the following components in parts by weight: 0.25 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.005 part of sodium hyaluronate, 0.005 part of gamma-polyglutamic acid and the molecular weight of the sodium hyaluronate is 150-200 ten thousand Da. Mixing the above materials.
Example 8
A suspension thickening composition consists of the following components in parts by weight: 0.25 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.01 part of sodium hyaluronate, 0.02 part of gamma-polyglutamic acid, and the molecular weight of the sodium hyaluronate is 150-200 ten thousand Da. Mixing the above materials.
Example 9
A suspension thickening composition consists of the following components in parts by weight: 0.25 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.02 part of sodium hyaluronate, 0.02 part of gamma-polyglutamic acid, and the molecular weight of the sodium hyaluronate is 150-200 ten thousand Da. Mixing the above materials.
Comparative example 1
A suspension thickening composition consists of the following components in parts by weight: and uniformly mixing 0.25 part of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer, 0 part of sodium hyaluronate and 0.02 part of gamma-polyglutamic acid.
Comparative example 2
A suspension thickening composition consists of the following components in parts by weight: 0.25 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.02 part of sodium hyaluronate, 0 part of gamma-polyglutamic acid and the molecular weight of the sodium hyaluronate is 150-200 Da. Mixing the above materials.
Comparative example 3
A suspension thickening composition consists of the following components in parts by weight: acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer 0.25 parts, sodium hyaluronate 0 parts and gamma-polyglutamic acid 0 parts. Mixing the above materials.
Comparative example 4
A suspension thickening composition consists of the following components in parts by weight: 0.25 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.01 part of sodium hyaluronate and 0.01 part of gamma-polyglutamic acid. The molecular weight of the sodium hyaluronate is 50-70 Da.
Comparative example 5
A suspension thickening composition consists of the following components in parts by weight: 0.25 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.04 part of sodium hyaluronate, 0.001 part of gamma-polyglutamic acid, and the molecular weight of the sodium hyaluronate is 150-200 ten thousand Da. Mixing the above materials.
Comparative example 6
A suspension thickening composition consists of the following components in parts by weight: 0.25 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.001 part of sodium hyaluronate, 0.04 part of gamma-polyglutamic acid, and the molecular weight of the sodium hyaluronate is 150-200 ten thousand Da. Mixing the above materials.
Comparative example 7
A suspension thickening composition consists of the following components in parts by weight: 0 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.01 part of sodium hyaluronate, 0.01 part of gamma-polyglutamic acid, and the molecular weight of the sodium hyaluronate is 150-200 Da. Mixing the above materials.
Application example 1
The compositions prepared in the above examples and comparative examples of the present invention can be used in cosmetics as ingredients of cosmetics. The types of cosmetics include, but are not limited to, skin care products such as cream, milky lotion, cream, etc. In the preparation process, the cosmetic comprises an alkali agent, an aqueous carrier and matrixes required for preparing various dosage forms besides the composition containing acrylic acid (esters)/C10-30 alkanol acrylate cross-linked polymer, hyaluronic acid or salt thereof and gamma-polyglutamic acid, wherein the matrixes can be used for selecting matrixes commonly used in different types of cosmetics according to the prior art, and the preparation method of the cosmetic can be carried out according to the conventional method of the prior art.
The alkaline agent serves to neutralize the suspension thickening composition, which may be selected from sodium hydroxide, aminomethylpropanol or arginine, and the aqueous carrier may be water.
Application example 2
To verify the excellent effect of the suspension thickening composition of the present invention, the compositions prepared in the above examples and comparative examples were prepared into a gel emulsion by the following method:
table 1 gel base formula
Table 2 content of ingredients in examples and comparative examples in gel milk
The preparation method of the gel milk comprises the following steps:
(1) Mixing and stirring the phase A raw materials uniformly;
(2) Adding phase B into phase A, mixing, homogenizing and stirring;
(3) Adding the phase C under the condition of well homogenizing the AB mixed phase, continuously homogenizing and stirring, and discharging to obtain the gel emulsion.
Experimental example 1 viscosity and stability test
Experimental instrument: electronic balance, constant temperature water bath, magnetic stirrer, optical microscope, rotary viscometer, centrifuge, stability incubator, etc.
The testing method comprises the following steps: the jelly emulsions prepared in examples 1 to 9 and comparative examples 1 to 7 were subjected to a viscosity test, a storage stability test and a centrifugal stability test. Viscosity test Each gel was measured by a viscosity tester (test conditions: brookfield DVRV, # 4, 1min,10rpm,25 ℃ C.) after being allowed to stand for 24 hours. The storage stability test is to observe the particle size of each gel milk by an optical microscope after standing at Room Temperature (RT), minus 20 ℃, 40 ℃ and 55 ℃ for 30 days, 5 days, 30 days and 5 days, and simultaneously observe the appearance of the gel milk (the appearance under the conditions of 40 ℃ for 30 days and 55 ℃ for 5 days is emphasized), and FIG. 1 is an optical microscope photograph of the gel milk prepared in example 1 after storing at 55 ℃ for 5 days. The centrifugal stability test is to separate each prepared gel milk for 30min under 3 centrifugal conditions of room temperature, 3000rpm/min, 6000rpm/min and 10000rpm/min, and then observe the layering condition of the product.
The test results are summarized in table 3 below.
TABLE 3 results of viscosity and stability tests
Experimental results
The test results show that the gel milk prepared by the suspension thickening composition of the embodiments 1-9 has good suspension stability, uniform particle size after long-term storage under different temperature conditions and good stability after centrifugation. From a comparison of example 1 and comparative examples 5, 6 and 7, the amount of the composition of the present invention was used to contribute to high temperature stability; as can be seen from a comparison of example 1 and comparative examples 1 to 3, the suspension stabilizing effect of the single acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer on the oil phase is poor, the simultaneous addition of hyaluronic acid and gamma-polyglutamic acid can achieve the optimal suspension stabilizing effect, and the simultaneous addition of hyaluronic acid and gamma-polyglutamic acid does not significantly reduce the viscosity of the system, and can improve the appearance of the emulsion. From the comparative analysis of example 1 and comparative example 4, it is understood that the molecular weight of hyaluronic acid also has an influence on the suspension stabilizing effect.
Experimental example 2 Stable suspension of different oils
The experimental method comprises the following steps: the stability test is carried out on the gel milk of application example 2 and the three types of gel milk respectively by replacing 20% of caprylic acid/capric acid glyceride in the gel milk formula of application example 2 with 20% of mineral oil, 20% of polydimethylsiloxane and 10% of octyl methoxycinnamate respectively to obtain three types of novel gel milk with different oil phases. The storage stability was obtained by allowing each of the jelly milks to stand and store at Room Temperature (RT), at-20 ℃, at 40 ℃ and at 55 ℃ for 30 days, 5 days, 30 days and 5 days, observing the particle size of each of the jelly milks by using an optical microscope, and centrifuging each of the stored products at 6000rpm for 30 minutes, and observing the layering condition, and the results are shown in Table 4.
TABLE 4 Table 4
/>
Experimental results
The test results show that the suspension thickening composition containing acrylic acid (esters)/C10-30 alkanol acrylate cross-linked polymer, hyaluronic acid and gamma-polyglutamic acid can suspend and stabilize caprylic acid/capric glyceride, mineral oil, polydimethylsiloxane, methoxy octyl cinnamate, and the application range of grease is wide.
Experimental example 3 study on suspension conditions of oils and fats with different contents
The experimental method comprises the following steps: the content of caprylic/capric glyceride in the gel formula of application example 2 is respectively adjusted to 25%, 30%, 35%, 40%, 45% and 50%, and the suspension stabilizing effect of the suspension thickening composition provided by the invention on oil phases with different contents is verified. Taking the gel milk formulas with different oil phase contents prepared by the suspension thickening compositions of examples 1-9 and comparative examples 1-6 as examples, centrifugal tests are respectively carried out on each gel milk under the test conditions: and 6000rpm for 30min, and observing the layering condition of the gel emulsion. The results are shown in Table 5.
TABLE 5
/>
Experimental results
As can be obtained through the analysis of the experimental data, the suspension thickening composition containing acrylic acid (esters)/C10-30 alkanol acrylate cross-linked polymer, hyaluronic acid and gamma-polyglutamic acid can stably suspend an oil phase with higher content.
Claims (13)
1. A suspension thickening composition, characterized by: the active ingredients are acrylic acid (esters)/C10-30 alkanol acrylate cross-linked polymer, hyaluronic acid or salt thereof and gamma-polyglutamic acid;
the weight parts of the effective components are as follows: the cross-linked polymer of acrylic acid (esters) and C10-30 alkanol acrylate is 0.1-0.5 part, 0.005-0.02 part of hyaluronic acid or salt thereof and 0.005-0.02 part of gamma-polyglutamic acid, wherein the molecular weight of the hyaluronic acid or salt thereof is 150-200W Da.
2. The suspension thickening composition according to claim 1, wherein: the weight parts of the effective components are as follows: the acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer is 0.2-0.4 part, hyaluronic acid or salt thereof is 0.005-0.01 part, and gamma-polyglutamic acid is 0.005-0.01 part.
3. Suspension thickening composition according to claim 1 or 2, characterized in that: the hyaluronate is a soluble salt of hyaluronic acid.
4. Suspension thickening composition according to claim 1 or 2, characterized in that: the hyaluronate is sodium hyaluronate, magnesium hyaluronate, zinc hyaluronate or potassium hyaluronate.
5. Use of the suspension thickening composition according to any one of claims 1 to 4 as an oil phase suspension stabilizer in cosmetics.
6. A cosmetic product characterized by: a suspension thickening composition comprising any of claims 1-4.
7. The cosmetic according to claim 6, characterized in that: the content of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer in the suspension thickening composition is 0.1-0.5wt% in the cosmetics; the content of hyaluronic acid or its salt in the suspension thickening composition is 0.005-0.02wt% in the cosmetic; the content of gamma-polyglutamic acid in the suspension thickening composition is 0.005-0.02wt% in the cosmetic.
8. The cosmetic according to claim 6, characterized in that: the content of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer in the suspension thickening composition is 0.2-0.4wt% in the cosmetic.
9. The cosmetic according to claim 6, characterized in that: the content of hyaluronic acid or its salt in the suspension thickening composition is 0.005-0.01wt% in the cosmetic.
10. The cosmetic according to claim 6, characterized in that: the content of gamma-polyglutamic acid in the suspension thickening composition is 0.005-0.01wt% in the cosmetic.
11. Cosmetic according to any one of claims 7 to 10, characterized in that it comprises: the alkaline agent is sodium hydroxide, aminomethylpropanol or arginine, and the carrier is water.
12. Cosmetic according to any one of claims 7 to 10, characterized in that it comprises: also comprises an oil phase, wherein the content of the oil phase is less than 50wt%.
13. Cosmetic according to any one of claims 7 to 10, characterized in that it comprises: the content of the oil phase is 45wt% or less.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111481629.9A CN114129471B (en) | 2021-12-06 | 2021-12-06 | Suspension thickening composition and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111481629.9A CN114129471B (en) | 2021-12-06 | 2021-12-06 | Suspension thickening composition and application thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114129471A CN114129471A (en) | 2022-03-04 |
| CN114129471B true CN114129471B (en) | 2023-07-18 |
Family
ID=80384201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111481629.9A Active CN114129471B (en) | 2021-12-06 | 2021-12-06 | Suspension thickening composition and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114129471B (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009147951A1 (en) * | 2008-06-02 | 2009-12-10 | 出光テクノファイン株式会社 | Thickening composition and process for production thereof |
| KR20180003443A (en) * | 2016-06-30 | 2018-01-09 | (주)아모레퍼시픽 | Cosmetic composition containing hyaluronic acids having different molecular weight |
| JP2021123592A (en) * | 2020-01-31 | 2021-08-30 | 株式会社コスモビューティー | Thickening composition |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080299068A1 (en) * | 2004-10-26 | 2008-12-04 | Shiseido Co., Ltd. | Skin Preparation For External Use |
| CN105255173B (en) * | 2015-11-10 | 2017-09-12 | 山东省药学科学院 | A kind of preparation method for being crosslinked polyglutamic acid hydrogel |
| CN107184427A (en) * | 2017-04-17 | 2017-09-22 | 杭州惠博士健康产业有限公司 | A kind of cooperative compositions and application containing polyglutamic acid and hyaluronic acid |
| CN107308014A (en) * | 2017-06-15 | 2017-11-03 | 曾万祥 | One kind thickening suspension composition and its application |
| CN107997988B (en) * | 2017-12-28 | 2019-04-23 | 花安堂生物科技集团有限公司 | A kind of high moisturizing thickener blend composition and its application in cosmetics |
| CN110075006B (en) * | 2019-04-19 | 2022-02-25 | 华熙生物科技股份有限公司 | Method for promoting solution compatibility of hyaluronic acid type substance and type II collagen and composition containing the same |
| CN112516008A (en) * | 2021-01-07 | 2021-03-19 | 华熙生物科技股份有限公司 | Thickener and application thereof in cosmetics |
-
2021
- 2021-12-06 CN CN202111481629.9A patent/CN114129471B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009147951A1 (en) * | 2008-06-02 | 2009-12-10 | 出光テクノファイン株式会社 | Thickening composition and process for production thereof |
| KR20180003443A (en) * | 2016-06-30 | 2018-01-09 | (주)아모레퍼시픽 | Cosmetic composition containing hyaluronic acids having different molecular weight |
| JP2021123592A (en) * | 2020-01-31 | 2021-08-30 | 株式会社コスモビューティー | Thickening composition |
Also Published As
| Publication number | Publication date |
|---|---|
| CN114129471A (en) | 2022-03-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2018222545A1 (en) | Poly(amino acid) rheology modifier compositions and methods of use | |
| EP2663393A1 (en) | Silicone emulsions and method for producing same | |
| CN109431866A (en) | A kind of skin care compositions of the system containing liquid crystal and preparation method thereof | |
| CN113663126A (en) | Injectable hyaluronic acid microsphere and preparation method and application thereof | |
| CN107049805A (en) | A kind of sunscreen spray and preparation method thereof | |
| CN114129471B (en) | Suspension thickening composition and application thereof | |
| CN113274308A (en) | Two-phase skin care composition and preparation method thereof | |
| CN115778856A (en) | Composition with thickening effect and application thereof in skin care products | |
| KR102344122B1 (en) | Gel composition, cosmetic, and method for preparing a gel composition | |
| WO2023020299A1 (en) | Stable composition carrying urea or derivative thereof | |
| CN111588653A (en) | Foundation make-up liquid and preparation method thereof | |
| TWI391175B (en) | Oil in water emulsion composition and method for manufacturing thereof | |
| CN112006923A (en) | High internal phase emulsion stabilized by low-content surfactant and preparation method thereof | |
| CN115399376B (en) | Type-controllable double-gel type lipid, preparation method thereof and 3D printing application | |
| CN114569496B (en) | Polymer thickener and preparation method and application thereof | |
| CN110343262A (en) | A kind of lotion and the preparation method and application thereof based on high-ester pectin colloidal sol | |
| CN112516008A (en) | Thickener and application thereof in cosmetics | |
| WO2021259580A1 (en) | Highly viscous cosmetic nanoemulsion | |
| US20210161794A1 (en) | Silicone alternatives | |
| CN108125814A (en) | A kind of hair care and skin care compositions of cation form work composition | |
| CN114983853A (en) | Low-viscosity stable D-phase emulsion and preparation method thereof | |
| CN109762953B (en) | Environment-friendly leather product curing agent | |
| CA2394729C (en) | Cosmetic product containing acrylates | |
| CN115919668A (en) | Oil-coagulated bead composition stably existing in emulsifying system | |
| WO2022248481A1 (en) | Hydrogels including biopolymers |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |