CN114126629B - 用于生成一氧化氮的方法和组合物及其用于经由呼吸道输送一氧化氮的用途 - Google Patents

用于生成一氧化氮的方法和组合物及其用于经由呼吸道输送一氧化氮的用途 Download PDF

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CN114126629B
CN114126629B CN202080052446.2A CN202080052446A CN114126629B CN 114126629 B CN114126629 B CN 114126629B CN 202080052446 A CN202080052446 A CN 202080052446A CN 114126629 B CN114126629 B CN 114126629B
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nitrite
organic
proton source
acid
nitric oxide
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CN114126629A (zh
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H·S·芒罗
C·B·伍德
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Thirty Breathing Co ltd
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Thirty Breathing Co ltd
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Priority claimed from GBGB1907971.4A external-priority patent/GB201907971D0/en
Priority claimed from GB201915277A external-priority patent/GB201915277D0/en
Priority claimed from GBGB2005979.6A external-priority patent/GB202005979D0/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
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    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
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  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
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  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Biomedical Technology (AREA)
  • Gynecology & Obstetrics (AREA)
CN202080052446.2A 2019-06-04 2020-06-02 用于生成一氧化氮的方法和组合物及其用于经由呼吸道输送一氧化氮的用途 Active CN114126629B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB1907971.4 2019-06-04
GBGB1907971.4A GB201907971D0 (en) 2019-06-04 2019-06-04 Methods and compositions for generating nitric oxide and uses thereof to deliver nitric oxide via the respiratory tract
GB1915277.6 2019-10-22
GB201915277A GB201915277D0 (en) 2019-10-22 2019-10-22 Methods and compositions for generating nitric oxide and uses thereof to deliver nitric oxide via the respiratory tract
GBGB2005979.6A GB202005979D0 (en) 2020-04-23 2020-04-23 Methods and compositions for generating nitric oxide and uses therof to deliver nitric oxide via the respiratory tract
GB2005979.6 2020-04-23
PCT/GB2020/051329 WO2020245574A1 (en) 2019-06-04 2020-06-02 Methods and compositions for generating nitric oxide and uses thereof to deliver nitric oxide via the respiratory tract

Publications (2)

Publication Number Publication Date
CN114126629A CN114126629A (zh) 2022-03-01
CN114126629B true CN114126629B (zh) 2024-08-30

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US (1) US20220257642A1 (enExample)
EP (1) EP3980032A1 (enExample)
JP (1) JP7686578B2 (enExample)
CN (1) CN114126629B (enExample)
AU (1) AU2020286987B2 (enExample)
BR (1) BR112021023632A2 (enExample)
CA (1) CA3142109A1 (enExample)
GB (1) GB2599818B (enExample)
WO (1) WO2020245574A1 (enExample)

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