CN114106491A - Degradable virus sampling tube and preparation method thereof - Google Patents
Degradable virus sampling tube and preparation method thereof Download PDFInfo
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L27/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers
- C08L27/02—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L27/04—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment containing chlorine atoms
- C08L27/06—Homopolymers or copolymers of vinyl chloride
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- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
- C08K3/20—Oxides; Hydroxides
- C08K3/22—Oxides; Hydroxides of metals
- C08K2003/2237—Oxides; Hydroxides of metals of titanium
- C08K2003/2241—Titanium dioxide
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- C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
- C08K3/24—Acids; Salts thereof
- C08K3/26—Carbonates; Bicarbonates
- C08K2003/265—Calcium, strontium or barium carbonate
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- C08L2205/02—Polymer mixtures characterised by other features containing two or more polymers of the same C08L -group
- C08L2205/025—Polymer mixtures characterised by other features containing two or more polymers of the same C08L -group containing two or more polymers of the same hierarchy C08L, and differing only in parameters such as density, comonomer content, molecular weight, structure
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Abstract
The application relates to the technical field of sampling pipes, and particularly discloses a degradable virus sampling pipe and a preparation method thereof, wherein the degradable virus sampling pipe comprises the following raw materials in parts by weight: 60-80 parts of polyvinyl chloride resin, 35-40 parts of polycaprolactone, 3.5-10 parts of superfine calcium carbonate, 15-25 parts of silk fibroin, 3-5 parts of benzophenone, 20-30 parts of polylactic acid, 1-3 parts of dioctyl terephthalate, 1-2 parts of methyl methacrylate-maleic anhydride and 10-20 parts of chloroform. The biodegradation rate and the photodegradation rate of the virus sampling tube can reach 77.01% and 17.08% at most, the tensile yield stress and the elongation at break are 32.4MPa and 16.5% respectively, the better biodegradability and the photodegradation are shown, and the higher tensile yield stress and the elongation at break are kept at the same time.
Description
Technical Field
The application relates to the field of sampling tubes, in particular to a degradable virus sampling tube material and a preparation method thereof.
Background
The virus sampling tube is usually a centrifuge tube for collecting, transporting and preserving virus samples such as new coronavirus, influenza, avian influenza, measles and the like. In medicine, in order to prevent cross infection, a disposable sampling tube is usually selected, and the used virus sampling tube is centrally treated by a pressure steam sterilization process or a chemical sterilization process such as a process of immersing the virus sampling tube in a disinfectant for sterilization.
The processing modes of the pressure steam sterilization and the chemical disinfection method effectively avoid the situation that the virus sampling pipe is secondarily infected, but the processed waste virus sampling pipe is buried underground and can be completely degraded only after dozens of years or even about two hundred years, and the waste virus sampling pipe can generate adverse effect on the pH value of soil, so that the soil environment is deteriorated; meanwhile, the abandoned virus sampling tube also threatens the survival of animals and harms the safety and health of the animals.
Disclosure of Invention
In order to provide a degradable virus sampling tube, the application provides a degradable virus sampling tube and a preparation method thereof.
In a first aspect, the present application provides a degradable virus sampling tube, which adopts the following technical scheme:
a degradable virus sampling tube comprises the following raw materials in parts by weight: 60-80 parts of polyvinyl chloride resin, 35-40 parts of polycaprolactone, 3.5-10 parts of superfine calcium carbonate, 15-25 parts of silk fibroin, 3-5 parts of benzophenone, 20-30 parts of polylactic acid, 1-3 parts of dioctyl terephthalate, 1-2 parts of methyl methacrylate-maleic anhydride and 10-20 parts of chloroform.
By adopting the technical scheme, the polyvinyl chloride resin and the polycaprolactone are main raw materials of the virus sampling tube, and the virus sampling tube has excellent flame retardant effect, chemical resistance and mechanical strength. The polycaprolactone has good biodegradability, biocompatibility and nontoxicity, and can be completely degraded into carbon dioxide and water in a natural environment for 6-12 months. The superfine calcium carbonate can further promote the degradation of polycaprolactone and can also improve the toughness of the virus sampling tube.
Compared with other natural fibers and a plurality of high-performance synthetic fibers, the silk fibroin has better mechanical property and compatibility, and can promote the degradation of the polyvinyl chloride resin. Benzophenone can be added as a photosensitizer, and can absorb radiation to generate photoinitiation under the irradiation of sunlight, so that intermolecular bonds can be weakened, and a long chain is broken into fragments, thereby reducing the performance of polyvinyl chloride resin and polycaprolactone, and the fragments are continuously oxidized and decomposed in nature to be degraded into low molecular weight compounds so as to promote the degradation of the polyvinyl chloride resin and polycaprolactone.
The polylactic acid has biodegradability, so that the virus sampling tube has biodegradability and is finally converted into carbon dioxide and water under the action of soil microorganism metabolism. Meanwhile, the polylactic acid has good thermal stability, and the prepared virus sampling tube has high transparency, glossiness, hand feeling and heat resistance besides degradability. In addition, the polylactic acid and the polycaprolactone are blended, so that the toughness and the stability of the polylactic acid can be enhanced, and the mechanical property of the polylactic acid is further improved.
The dioctyl terephthalate is added as a plasticizer, has higher heat resistance, cold resistance, difficult volatilization and flexibility, has stronger dissolving power to polyvinyl chloride resin, reduces the hardness of each raw material, improves the flexibility, is easy to stretch and make into various shapes, is convenient for forming the virus sampling tube, and the prepared virus sampling tube has good water resistance. The compatibility of methyl methacrylate-maleic anhydride is better, the compatibility between the superfine calcium carbonate and the polycaprolactone and the polyvinyl chloride resin can be improved, the tensile strength and the impact strength of the product can be improved, the using amount of the polyvinyl chloride resin and the polycaprolactone can be reduced, the processing flowability can be improved, and the surface smoothness can be improved. Chloroform is added as an organic solvent to dissolve benzophenone, polylactic acid and dimethyl phthalate, and the dispersibility of the benzophenone, the polylactic acid and the dimethyl phthalate in the system is improved, so that the degradation of the virus sampling tube is further promoted.
Preferably, the method comprises the following steps: a degradable virus sampling tube comprises the following raw materials in parts by weight: 65-75 parts of polyvinyl chloride resin, 35-40 parts of polycaprolactone, 3.5-10 parts of superfine calcium carbonate, 15-25 parts of silk fibroin, 3-5 parts of benzophenone, 20-30 parts of polylactic acid, 1.5-2.5 parts of dioctyl terephthalate, 1.2-1.8 parts of methyl methacrylate-maleic anhydride and 14-18 parts of chloroform.
Preferably, the method comprises the following steps: the virus sampling tube also comprises the following raw materials in parts by weight: 3-7 parts of nano titanium dioxide and 10-25 parts of isopropanol.
In one embodiment of the present application, the degradable virus sampling tube comprises the following raw materials in parts by weight: 60-80 parts of polyvinyl chloride resin, 35-40 parts of polycaprolactone, 3.5-10 parts of superfine calcium carbonate, 15-25 parts of silk fibroin, 3-5 parts of benzophenone, 20-30 parts of polylactic acid, 1-3 parts of dioctyl terephthalate, 1-2 parts of methyl methacrylate-maleic anhydride, 10-20 parts of chloroform, 3-7 parts of nano titanium dioxide and 10-25 parts of isopropanol.
By adopting the technical scheme, the nano titanium dioxide can be used as a photodegradation promoter to be added, has the characteristics of small particle size, large specific surface area, high surface activity, good dispersibility and the like, and has better transparency and ultraviolet absorptivity. Under the irradiation of sunlight, radiation is utilized to generate free radicals with stronger activity in a reaction system, so that bonds between molecules of the polyvinyl chloride resin and the polycaprolactone are broken, and the degradation of the virus sampling tube is promoted. The addition of the isopropanol ensures that the nano titanium dioxide is dispersed more uniformly.
Preferably, the method comprises the following steps: the nano titanium dioxide is obtained by modifying with titanate coupling agent.
By adopting the technical scheme, the surface of the nano titanium dioxide is modified by adopting the titanate coupling agent, and the titanate coupling agent reacts with hydroxyl on the surface of the nano titanium dioxide, so that the stability of combination between the nano titanium dioxide and other components is improved, and the dispersion effect of the nano titanium dioxide is improved.
Preferably, the method comprises the following steps: the weight ratio of the titanate coupling agent to the nano titanium dioxide is 1: (10-15).
By adopting the technical scheme, the weight ratio of the titanate coupling agent to the nano titanium dioxide is adjusted, and the dispersibility of the nano titanium dioxide in the system is improved, so that the degradation of the virus sampling tube is promoted.
Preferably, the virus sampling tube further comprises the following raw materials in parts by weight: 30-35 parts of paraffin.
In one embodiment of the present application, the degradable virus sampling tube comprises the following raw materials in parts by weight: 60-80 parts of polyvinyl chloride resin, 35-40 parts of polycaprolactone, 3.5-10 parts of superfine calcium carbonate, 15-25 parts of silk fibroin, 3-5 parts of benzophenone, 20-30 parts of polylactic acid, 1-3 parts of dioctyl terephthalate, 1-2 parts of methyl methacrylate-maleic anhydride, 10-20 parts of chloroform and 30-35 parts of paraffin.
In one embodiment of the present application, the degradable virus sampling tube comprises the following raw materials in parts by weight: 60-80 parts of polyvinyl chloride resin, 35-40 parts of polycaprolactone, 3.5-10 parts of superfine calcium carbonate, 15-25 parts of silk fibroin, 3-5 parts of benzophenone, 20-30 parts of polylactic acid, 1-3 parts of dioctyl terephthalate, 1-2 parts of methyl methacrylate-maleic anhydride, 10-20 parts of chloroform, 3-7 parts of nano titanium dioxide, 10-25 parts of isopropanol and 30-35 parts of paraffin.
By adopting the technical scheme, the toughness of the virus sampling tube can be improved by adding the paraffin, and meanwhile, the water absorption performance of the silk fibroin can be improved by the paraffin, so that the hydrolysis of the silk fibroin is promoted, and the degradation of the virus sampling tube is facilitated.
Preferably, the method comprises the following steps: the weight ratio of the silk fibroin to the paraffin is 1: (0.5-0.7).
By adopting the technical scheme, the weight ratio of the paraffin to the silk fibroin is adjusted to improve the hydrolysis speed of the silk fibroin and further promote the degradation of the virus sampling tube.
Preferably, the method comprises the following steps: the weight ratio of the superfine calcium carbonate to the polycaprolactone is 1: (4-10).
By adopting the technical scheme, the weight ratio of the superfine calcium carbonate to the polycaprolactone is adjusted, and the degradation rate of the polycaprolactone can be improved.
In a second aspect, the present application provides a method for preparing a virus sampling tube, which is specifically realized by the following technical scheme:
a preparation method of a virus sampling tube comprises the following operation steps:
mixing polyvinyl chloride resin and polycaprolactone, heating and uniformly stirring to obtain a mixture A;
sequentially adding benzophenone, polylactic acid and dioctyl terephthalate into chloroform, and uniformly stirring to obtain a mixture B;
and adding the mixture B and the rest raw materials into the mixture A, uniformly mixing, heating, injection molding, cooling and forming to obtain the virus sampling tube.
In summary, the present application includes at least one of the following beneficial technical effects:
(1) according to the application, the degradability of polycaprolactone is further promoted by controlling the weight ratio of the superfine calcium carbonate to the polycaprolactone in the raw materials of the virus sampling tube, so that the biodegradation rate and the photodegradation rate of the virus sampling tube are respectively 73.38% and 14.35%, the tensile yield stress and the elongation at break are respectively 31.9MPa and 18.1%, and the excellent biodegradability and photodegradation are shown.
(2) According to the method, the nano titanium dioxide and the isopropanol are added into the raw materials of the virus sampling tube, the surface of the nano titanium dioxide is modified by adopting the titanate coupling agent, the dispersity of the nano titanium dioxide in a raw material system is improved, the biodegradation rate and the photodegradation rate of the virus sampling tube are respectively 75.41% and 16.49%, the tensile yield stress and the elongation at break are respectively 32.0MPa and 17.6%, the better biodegradability and the higher tensile yield stress and elongation at break are shown, and the higher tensile yield stress and elongation at break are kept.
(3) The method further promotes the degradability of the silk fibroin by controlling the weight ratio of the silk fibroin to the paraffin in the raw materials of the virus sampling tube, so that the biodegradation rate and the photodegradation rate of the virus sampling tube are respectively 77.01% and 17.80%, the tensile yield stress and the elongation at break are respectively 32.4MPa and 16.5%, and the virus sampling tube shows better biodegradability and photodegradation.
Detailed Description
The present application will be described in further detail with reference to specific examples.
The following raw materials are all commercially available products, and are all fully disclosed, and should not be understood as limiting the sources of the raw materials, and specifically: the polyvinyl chloride resin is selected from Nibo wei optical plastication Co., Ltd, and is TPH-31; the polycaprolactone is selected from environment-friendly science and technology limited of Jinnan Wandefeng; the superfine calcium carbonate is selected from a Lingshou county Touda mineral product processing plant, and the granularity is 800 meshes; the silk fibroin is selected from Sienrireli bioengineering, Inc., with product number REL 0512; the nanometer titanium dioxide is selected from Ningbo Ningwei New Material science and technology company, and the granularity is 5 nm; the paraffin is selected from Xiangmao International trade company Limited, model number 58 #.
Example 1
The virus sampling tube is prepared by the following method:
referring to the mixing amount in the table 1, mixing the polyvinyl chloride resin and the polycaprolactone, heating at 220 ℃, and uniformly stirring to obtain a molten mixture A;
sequentially adding benzophenone, polylactic acid and dioctyl terephthalate into chloroform, and uniformly stirring to obtain a mixture B;
adding superfine calcium carbonate, silk fibroin, methyl methacrylate-maleic anhydride, chloroform and the mixture B into the mixture A, uniformly mixing, heating and injection molding at 250 ℃, cooling to 23 ℃ and forming to obtain the virus sampling tube.
Examples 2 to 5
The virus sampling tubes of examples 2-5 were prepared in the same manner and with the same types of raw materials as in example 1, except that the amounts of the raw materials were different, as shown in Table 1.
TABLE 1 EXAMPLES 1-5 amount of each raw material (unit: kg) of virus sampling tube
Examples 6 to 9
The degradable virus sampling tubes of examples 6-9 are identical to those of example 3 in preparation method and material types, except that the amount of each material is different, and the details are shown in table 2.
TABLE 2 examples 6-9 amount of each raw material (unit: kg) of virus sampling tube
Examples 10 to 12
The degradable virus sampling tubes of examples 10-12 are identical to those of example 3 in preparation method and material types, except that the amount of each material is different, and the details are shown in table 3.
TABLE 3 examples 10-12 mixing amounts (unit: kg) of respective raw materials of virus sampling tubes
Example 13
The virus sampling tube is prepared by the following method:
referring to the mixing amount in the table 4, adding the nano titanium dioxide into isopropanol, and uniformly dispersing to obtain a mixture A;
mixing polyvinyl chloride resin and polycaprolactone, heating at 220 ℃, and uniformly stirring to obtain a molten mixture B; sequentially adding benzophenone, polylactic acid and dioctyl terephthalate into chloroform, and uniformly stirring to obtain a mixture C; adding the mixture A, the superfine calcium carbonate, the silk fibroin, the methyl methacrylate-maleic anhydride, the chloroform and the mixture C into the mixture B, uniformly mixing, heating and injection molding at 250 ℃, cooling to 23 ℃ and forming to obtain the virus sampling tube.
Example 14
The virus sampling tube is prepared by the following method:
referring to the mixing amount in the table 4, adding the nano titanium dioxide into isopropanol, carrying out ultrasonic oscillation for 20min, dispersing uniformly, adding a titanate coupling agent, stirring in a water bath at the constant temperature of 90 ℃ for 2h, cooling to 23 ℃, carrying out suction filtration, drying at the temperature of 100 ℃, and crushing to 5nm to obtain modified nano titanium dioxide;
adding the modified nano titanium dioxide into isopropanol, and uniformly dispersing to obtain a mixture A;
mixing polyvinyl chloride resin and polycaprolactone, heating and uniformly stirring to obtain a mixture B;
sequentially adding benzophenone, polylactic acid and dioctyl terephthalate into chloroform, and uniformly stirring to obtain a mixture C;
and adding the mixture A, the superfine calcium carbonate, the silk fibroin, the methyl methacrylate-maleic anhydride, the chloroform and the mixture C into the mixture B, uniformly mixing, heating for injection molding, and cooling for molding to obtain the virus sampling tube.
Examples 15 to 16
The degradable virus sampling tubes of examples 15-16 were prepared by the same method and using the same types of raw materials as those of example 14, except that the amounts of the raw materials were different, as shown in Table 4.
TABLE 4 examples 13-16 Virus sampling tubes for each raw material dosage (unit: kg)
Examples 17 to 19
The degradable virus sampling tubes of examples 17-19 were prepared by the same method and using the same types of raw materials as those of example 15, except that the amounts of the raw materials were different, as shown in Table 5.
TABLE 5 examples 17-19 Virus sampling tubes for the amounts of each raw material (unit: kg)
Examples 20 to 23
The degradable virus sampling tubes of examples 20 to 23 were prepared in the same manner and with the same types of raw materials as those of example 11, except that the amounts of the raw materials were different, as shown in Table 6.
TABLE 6 examples 20-23 Virus sampling tubes for the amounts of each raw material (unit: kg)
Example 24
The degradable virus sampling tube of example 24 was prepared in exactly the same manner as in example 18, except that 33.3kg of paraffin was added, and the types and amounts of the remaining raw materials were exactly the same as in example 18.
Comparative example 1
The virus sampling tube of comparative example 1 was prepared exactly the same as in example 1, except that: the polycaprolactone in the raw material of the virus sampling tube is replaced by polyvinyl chloride resin in equal amount, and the other raw materials and the mixing amount are the same as those in the example 1.
Comparative example 2
The virus sampling tube of comparative example 2 was prepared exactly the same as in example 1, except that: the raw materials of the virus sampling tube are not added with superfine calcium carbonate, and the other raw materials and the mixing amount are the same as those in the example 1.
Comparative example 3
The virus sampling tube of comparative example 3 was prepared exactly the same as in example 1, except that: silk fibroin is not added in the raw materials of the virus sampling tube, and the other raw materials and the mixing amount are the same as those in the embodiment 1.
Comparative example 4
The virus sampling tube of comparative example 4 was prepared exactly as in example 1, except that: benzophenone is not added in the raw materials of the virus sampling tube, and the other raw materials and the mixing amount are the same as those in the example 1.
Comparative example 5
The virus sampling tube of comparative example 5 was prepared exactly the same as in example 1, except that: polylactic acid is not added in the raw materials of the virus sampling tube, and the other raw materials and the mixing amount are the same as those in the example 1.
Performance detection
The following test standards or methods were used to test the performance of the various examples 1-24 and comparative examples 1-5, respectively, and the results are detailed in Table 7.
The biodegradation rate is as follows: and the biodegradation rate is detected by adopting a GB/T19276.2 method to the virus sampling tube.
The photodegradation rate: and the light degradation rate GB/T16422.2 is used for detecting the light degradation rate by adopting a method of exposing in a xenon lamp artificial accelerated aging box.
Tensile strength, elongation at break: and (3) detecting the tensile strength and the elongation at break of the virus sampling tube by adopting a method of GB/T8804.1-2003 thermoplastic plastic tube tensile property measurement.
TABLE 7 Performance test results for different virus sampling tubes
The detection results in Table 7 show that the biodegradation rate and the photodegradation rate of the virus sampling tubes of examples 1 to 24 in the application can reach 78.01 percent and 18.08 percent at most, which are higher than those of the virus sampling tubes of comparative examples 1 to 5; meanwhile, the tensile yield stress and the elongation at break of the virus sampling tube are respectively 32.4MPa and 16.5 percent, which are higher than those of the virus sampling tubes of comparative examples 1 to 5, so that the degradation rate of the virus sampling tube is improved, and the tensile yield stress and the elongation at break of the virus sampling tube are ensured.
In examples 1-5, the biodegradation rate and the photodegradation rate of the virus sampling tube of example 3 were 72.07% and 13.37%, respectively, which are higher than those of the virus sampling tubes of examples 1-2 and examples 4-5; the tensile yield stress and the elongation at break of the virus sampling tube in example 3 are respectively 33.9MPa and 19.6 percent, which are higher than those of the virus sampling tubes in examples 1-2 and examples 4-5, and show that the weight parts of polyvinyl chloride resin, dioctyl terephthalate, methyl methacrylate-maleic anhydride and chloroform in the raw materials of the virus sampling tube in example 3 are more suitable, the biodegradability and the photodegradability are better, and the tensile yield stress and the elongation at break are higher.
In example 3 and examples 6-9, the biodegradation rate and the photodegradation rate of the virus sampling tube of example 3 were higher than those of the virus sampling tubes of examples 6-9; the tensile yield stress and the elongation at break of the virus sampling tube in the example 3 are higher than those of the virus sampling tubes in the examples 6 to 9, which shows that the weight parts of benzophenone and polylactic acid in the raw material of the virus sampling tube in the example 3 are more suitable, the biodegradability and the photodegradability are better, and the tensile yield stress and the elongation at break are higher.
In examples 10-12, the biodegradation rate and the photodegradation rate of the virus sampling tube of example 11 were 73.38% and 14.35%, respectively, which were higher than those of the virus sampling tubes of examples 10 and 12; the tensile yield stress and the elongation at break of the virus sampling tube in example 11 are respectively 31.9MPa and 18.1 percent, which are higher than those of the virus sampling tubes in examples 10 and 12, and the results show that the weight ratio of the ultrafine calcium carbonate to the polycaprolactone in the raw materials of the virus sampling tube in example 11 is 1:6, so that the virus sampling tube has excellent biodegradability and photodegradability, and high tensile yield stress and elongation at break are maintained.
In examples 13-16, the biodegradation rate and the photodegradation rate of the virus sampling tubes of example 15 were 75.41% and 16.49%, respectively, which are higher than those of the virus sampling tubes of examples 13-14 and example 16; the tensile yield stress and the elongation at break of the virus sampling tube in example 15 are respectively 32.0MPa and 17.6 percent, which are higher than those of the virus sampling tubes in examples 13-14 and example 16, which shows that the weight parts of isopropanol in the raw material of the virus sampling tube in example 15 are proper, and the virus sampling tube shows excellent biodegradability and photodegradation after the nano titanium dioxide is modified, and keeps higher tensile yield stress and elongation at break.
In examples 17-19, the biodegradation rate and the photodegradation rate of the virus sampling tube of example 18 were 76.95% and 17.75%, respectively, which are higher than those of the virus sampling tubes of examples 17 and 19; the tensile yield stress and the elongation at break of the virus sampling tube in example 18 are respectively 32.0MPa and 17.0 percent, which are higher than those of the virus sampling tubes in examples 17 and 19, and the results show that the raw materials of the virus sampling tube in example 18 have a proper weight ratio of titanate coupling agent to nano titanium dioxide of 1:12.5, so that the virus sampling tube has excellent biodegradability and photodegradability, and simultaneously maintains higher tensile yield stress and elongation at break.
In examples 20-23, the biodegradation rate and the photodegradation rate of the virus sampling tube of example 21 were 75.01% and 14.40%, respectively, which were higher than those of the virus sampling tubes of examples 20 and 22-23; the tensile yield stress and the elongation at break of the virus sampling tube in example 21 are respectively 31.6MPa and 17.1 percent, which are higher than those of the virus sampling tubes in examples 20 and 22-23, and the results show that the raw material of the virus sampling tube in example 21 has a proper weight ratio of paraffin to silk fibroin of 1:0.6, so that the virus sampling tube shows excellent biodegradability and photodegradability, and keeps higher tensile yield stress and elongation at break.
In example 24, the biodegradation rate and the photodegradation rate of the virus sampling tube were 77.01% and 17.08%, respectively, which are higher than those of the virus sampling tubes of examples 20 to 23, indicating that the degradability of the virus sampling tube can be further improved by adding paraffin wax based on the addition of nano titanium dioxide, titanate coupling agent and isopropanol as raw materials.
In addition, the data of various indexes of comparative example 1 and comparative examples 1-5 show that the degradability of the virus sampling tube is improved to different degrees by adding polyvinyl chloride resin, superfine calcium carbonate, silk fibroin, benzophenone and polylactic acid into the raw materials.
The present embodiment is only for explaining the present application, and it is not limited to the present application, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present application.
Claims (9)
1. A degradable virus sampling tube is characterized by comprising the following raw materials in parts by weight: 60-80 parts of polyvinyl chloride resin, 35-40 parts of polycaprolactone, 3.5-10 parts of superfine calcium carbonate, 15-25 parts of silk fibroin, 3-5 parts of benzophenone, 20-30 parts of polylactic acid, 1-3 parts of dioctyl terephthalate, 1-2 parts of methyl methacrylate-maleic anhydride and 10-20 parts of chloroform.
2. The degradable virus sampling tube of claim 1, which comprises the following raw materials in parts by weight: 65-75 parts of polyvinyl chloride resin, 35-40 parts of polycaprolactone, 3.5-10 parts of superfine calcium carbonate, 15-25 parts of silk fibroin, 3-5 parts of benzophenone, 20-30 parts of polylactic acid, 1.5-2.5 parts of dioctyl terephthalate, 1.2-1.8 parts of methyl methacrylate-maleic anhydride and 14-18 parts of chloroform.
3. The degradable virus sampling tube of claim 1, further comprising the following raw materials in parts by weight: 3-7 parts of nano titanium dioxide and 10-25 parts of isopropanol.
4. The degradable virus sampling tube of claim 3, wherein: the nano titanium dioxide is obtained by modifying with titanate coupling agent.
5. The degradable virus sampling tube of claim 4, wherein: the weight ratio of the titanate coupling agent to the nano titanium dioxide is 1: (10-15).
6. The degradable virus sampling tube of claim 1, wherein: the virus sampling tube also comprises the following raw materials in parts by weight: 30-35 parts of paraffin.
7. The degradable virus sampling tube of claim 6, wherein: the weight ratio of the silk fibroin to the paraffin is 1: (0.5-0.7).
8. The degradable virus sampling tube of claim 1, wherein: the weight ratio of the superfine calcium carbonate to the polycaprolactone is 1: (4-10).
9. A method for preparing a degradable virus sampling tube according to any one of claims 1 to 8, comprising the following steps:
mixing polyvinyl chloride resin and polycaprolactone, heating and uniformly stirring to obtain a molten mixture A;
sequentially adding benzophenone, polylactic acid and dioctyl terephthalate into chloroform, and uniformly stirring to obtain a mixture B;
and adding the mixture B and the rest raw materials into the mixture A, uniformly mixing, heating, injection molding, cooling and forming to obtain the virus sampling tube.
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| CN202111624364.3A CN114106491A (en) | 2021-12-28 | 2021-12-28 | Degradable virus sampling tube and preparation method thereof |
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| CN202111624364.3A CN114106491A (en) | 2021-12-28 | 2021-12-28 | Degradable virus sampling tube and preparation method thereof |
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