CN114096567A - 糖磷脂聚合物网络及其用途 - Google Patents

糖磷脂聚合物网络及其用途 Download PDF

Info

Publication number
CN114096567A
CN114096567A CN202080030526.8A CN202080030526A CN114096567A CN 114096567 A CN114096567 A CN 114096567A CN 202080030526 A CN202080030526 A CN 202080030526A CN 114096567 A CN114096567 A CN 114096567A
Authority
CN
China
Prior art keywords
glycophospholipid
polymer
reaction product
phospholipids
cross
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202080030526.8A
Other languages
English (en)
Chinese (zh)
Inventor
A·K·阿瓦斯希
J·A·小迪贝拉
M·R·米斯
A·穆斯勒
G·L·格鲁贝三世
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bausch and Lomb Inc
Original Assignee
Bausch and Lomb Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch and Lomb Inc filed Critical Bausch and Lomb Inc
Publication of CN114096567A publication Critical patent/CN114096567A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/02—Anionic compounds
    • C11D1/32—Protein hydrolysates; Fatty acid condensates thereof
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005—Other compounding ingredients characterised by their effect
    • C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/10—Optical coatings produced by application to, or surface treatment of, optical elements
    • G02B1/18—Coatings for keeping optical surfaces clean, e.g. hydrophobic or photo-catalytic films
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B25/00—Packaging other articles presenting special problems
    • B65B25/008—Packaging other articles presenting special problems packaging of contact lenses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Optics & Photonics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • General Physics & Mathematics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Eyeglasses (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN202080030526.8A 2019-04-29 2020-03-11 糖磷脂聚合物网络及其用途 Pending CN114096567A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962839918P 2019-04-29 2019-04-29
US62/839,918 2019-04-29
PCT/US2020/022022 WO2020222914A1 (en) 2019-04-29 2020-03-11 Glycophospholipid polymeric network and use thereof

Publications (1)

Publication Number Publication Date
CN114096567A true CN114096567A (zh) 2022-02-25

Family

ID=70110413

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080030526.8A Pending CN114096567A (zh) 2019-04-29 2020-03-11 糖磷脂聚合物网络及其用途

Country Status (8)

Country Link
US (3) US11673974B2 (https=)
EP (1) EP3962961A1 (https=)
JP (1) JP7619961B2 (https=)
KR (1) KR102854452B1 (https=)
CN (1) CN114096567A (https=)
CA (1) CA3132335A1 (https=)
MX (1) MX2021012576A (https=)
WO (1) WO2020222914A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109260517B (zh) * 2018-09-19 2020-10-30 杭州启明医疗器械股份有限公司 一种可预装干燥生物心脏瓣膜及其制备方法
US11673974B2 (en) * 2019-04-29 2023-06-13 Bausch & Lomb Incorporated Glycophospholipid polymeric network and use thereof
US12582742B2 (en) * 2021-03-11 2026-03-24 Bausch + Lomb Ireland Limited Packaging solutions
US12012238B2 (en) * 2021-05-26 2024-06-18 Bausch + Lomb Ireland Limited Packaging solutions
US20230159202A1 (en) * 2021-11-23 2023-05-25 Bausch + Lomb Ireland Limited Method for making a preservative-free packaged ophthalmic device product
US20250040673A1 (en) * 2023-07-28 2025-02-06 Bausch + Lomb Ireland Limited Packaging solutions
IT202300019488A1 (it) * 2023-09-21 2025-03-21 D&V Farma Soc A Responsabilita Limitata Composizioni, usi e metodi per il trattamento della sindrome dell’occhio secco o per promuovere la guarigione delle ferite corneali

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1493754A1 (en) * 2002-04-09 2005-01-05 Shiseido Company, Ltd. Polysaccharide containing phosphorylcholine group and process for producing the same
US20080113935A1 (en) * 2004-03-02 2008-05-15 Saul Yedgar Use of lipid conjugates in the treatment of diseases or disorders of the eye
JP2016056267A (ja) * 2014-09-09 2016-04-21 日油株式会社 ホスホリルコリン基含有糖誘導体及びその製造方法

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL285986A (https=) 1961-12-27
NL128305C (https=) 1963-09-11
US4113224A (en) 1975-04-08 1978-09-12 Bausch & Lomb Incorporated Apparatus for forming optical lenses
US4197266A (en) 1974-05-06 1980-04-08 Bausch & Lomb Incorporated Method for forming optical lenses
US4143949A (en) 1976-10-28 1979-03-13 Bausch & Lomb Incorporated Process for putting a hydrophilic coating on a hydrophobic contact lens
US4136250A (en) 1977-07-20 1979-01-23 Ciba-Geigy Corporation Polysiloxane hydrogels
US4153641A (en) 1977-07-25 1979-05-08 Bausch & Lomb Incorporated Polysiloxane composition and contact lens
US4312575A (en) 1979-09-18 1982-01-26 Peyman Gholam A Soft corneal contact lens with tightly cross-linked polymer coating and method of making same
US4555732A (en) 1984-03-22 1985-11-26 Xerox Corporation Image sensor correction system
US4758595A (en) 1984-12-11 1988-07-19 Bausch & Lomb Incorporated Disinfecting and preserving systems and methods of use
US4740533A (en) 1987-07-28 1988-04-26 Ciba-Geigy Corporation Wettable, flexible, oxygen permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units, and use thereof
US5271876A (en) 1986-12-02 1993-12-21 Solomat Partners, L.P. Process for analyzing, monitoring and/or controlling the internal structure of non-conductive, moldable material by inducing an electrical effect therein before it is molded
US4910277A (en) 1988-02-09 1990-03-20 Bambury Ronald E Hydrophilic oxygen permeable polymers
US4954587A (en) 1988-07-05 1990-09-04 Ciba-Geigy Corporation Dimethylacrylamide-copolymer hydrogels with high oxygen permeability
US5070215A (en) 1989-05-02 1991-12-03 Bausch & Lomb Incorporated Novel vinyl carbonate and vinyl carbamate contact lens material monomers
US5034461A (en) 1989-06-07 1991-07-23 Bausch & Lomb Incorporated Novel prepolymers useful in biomedical devices
US5010141A (en) 1989-10-25 1991-04-23 Ciba-Geigy Corporation Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof
US5079319A (en) 1989-10-25 1992-01-07 Ciba-Geigy Corporation Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof
WO1992001720A1 (fr) 1990-07-24 1992-02-06 Seikagaku Kogyo Kabushiki Kaisha Glycosaminoglycane se combinant a un phospholipide ou a un lipide, production de ce compose et inhibiteur de metastase du cancer
US5310779A (en) 1991-11-05 1994-05-10 Bausch & Lomb Incorporated UV curable crosslinking agents useful in copolymerization
US5358995A (en) 1992-05-15 1994-10-25 Bausch & Lomb Incorporated Surface wettable silicone hydrogels
US5260000A (en) 1992-08-03 1993-11-09 Bausch & Lomb Incorporated Process for making silicone containing hydrogel lenses
IL106922A (en) 1992-09-14 1998-08-16 Novartis Ag Composite materials with one or more wettable surfaces and process for their preparation
US5321108A (en) 1993-02-12 1994-06-14 Bausch & Lomb Incorporated Fluorosilicone hydrogels
US5616757A (en) 1993-04-08 1997-04-01 Bausch & Lomb Incorporated Organosilicon-containing materials useful for biomedical devices
US5573726A (en) 1993-09-22 1996-11-12 Alcon Laboratories, Inc. Use of amidoamines in ophthalmic compositions
US5464667A (en) 1994-08-16 1995-11-07 Minnesota Mining And Manufacturing Company Jet plasma process and apparatus
US5760100B1 (en) 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
BR9612119A (pt) 1995-12-07 1999-02-17 Bausch & Lomb Unidade monomérica composição de hidrogel lente de contato e método para produzir uma composição de hidrogel
US5714557A (en) 1995-12-07 1998-02-03 Bausch & Lomb Incorporated Monomeric units useful for reducing the modulus of low water polymeric silicone compositions
US5708094A (en) 1996-12-17 1998-01-13 Bausch & Lomb Incorporated Polybutadiene-based compositions for contact lenses
JP4266571B2 (ja) 2002-05-17 2009-05-20 生化学工業株式会社 脂質結合グリコサミノグリカンの製造法
FR2844080B1 (fr) 2002-08-27 2005-03-04 Ge Med Sys Global Tech Co Llc Methode d'amelioration de la visualisation d'un vaisseau sanguin a partir de technique de reconstruction d'images synchronisees
EP1694712A1 (en) 2003-12-04 2006-08-30 University of Utah Research Foundation Modified macromolecules and methods of making and using thereof
DE602005022345D1 (de) 2004-11-29 2010-08-26 Shiseido Co Ltd Eine phosphorylcholingruppe enthaltende verbindung, und verfahren zu ihrer herstellung
US7674781B2 (en) 2006-04-28 2010-03-09 Heather Sheardown Hyaluronic acid-retaining polymers
WO2008063520A1 (en) * 2006-11-13 2008-05-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Contact lens compositions
US8490782B2 (en) * 2007-10-23 2013-07-23 Bausch & Lomb Incorporated Packaging solutions
US20100086512A1 (en) 2008-10-02 2010-04-08 Rolf Schaefer Mucomimetic compositions and uses therefore
US20100178317A1 (en) 2009-01-09 2010-07-15 Burke Susan E Lens Care Solutions with Hyaluronic Acid
EP2253370B1 (en) 2009-05-20 2014-10-01 Gambro Lundia AB Hollow fibre membranes having improved performance
IT1399351B1 (it) 2009-06-16 2013-04-16 Fidia Farmaceutici Procedimento per la sintesi di coniugati di glicosamminoglicani (gag) con molecole biologicamente attive, coniugati polimerici e usi relativi
JP5800369B2 (ja) 2009-07-09 2015-10-28 ボシュ・アンド・ロム・インコーポレイテッドＢａｕｓｃｈ ＆ Ｌｏｍｂ Ｉｎｃｏｒｐｏｒａｔｅｄ モノエチレン系不飽和重合性基含有ポリカルボシロキサンモノマー
US7994356B2 (en) 2009-07-09 2011-08-09 Bausch & Lomb Incorporated Mono ethylenically unsaturated polycarbosiloxane monomers
US7915323B2 (en) 2009-07-09 2011-03-29 Bausch & Lamb Incorporated Mono ethylenically unsaturated polycarbosiloxane monomers
WO2014169301A1 (en) 2013-04-12 2014-10-16 Bui The Duy Systems and methods for delivering cross-linked halyuronic acid into a patient
CN103665028B (zh) 2013-12-27 2016-05-04 天津市医药集团技术发展有限公司 一种L-α-甘磷酸胆碱的制备方法
PL3072503T3 (pl) 2015-03-26 2021-01-11 D.M.G. Italia Srl Kompozycja okulistyczna do ochrony rogówki
US11673974B2 (en) * 2019-04-29 2023-06-13 Bausch & Lomb Incorporated Glycophospholipid polymeric network and use thereof
US12012238B2 (en) * 2021-05-26 2024-06-18 Bausch + Lomb Ireland Limited Packaging solutions

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1493754A1 (en) * 2002-04-09 2005-01-05 Shiseido Company, Ltd. Polysaccharide containing phosphorylcholine group and process for producing the same
US20080113935A1 (en) * 2004-03-02 2008-05-15 Saul Yedgar Use of lipid conjugates in the treatment of diseases or disorders of the eye
JP2016056267A (ja) * 2014-09-09 2016-04-21 日油株式会社 ホスホリルコリン基含有糖誘導体及びその製造方法

Also Published As

Publication number Publication date
US20250154289A1 (en) 2025-05-15
JP2022530253A (ja) 2022-06-28
CA3132335A1 (en) 2020-11-05
WO2020222914A1 (en) 2020-11-05
JP7619961B2 (ja) 2025-01-22
KR102854452B1 (ko) 2025-09-03
US20230257485A1 (en) 2023-08-17
EP3962961A1 (en) 2022-03-09
US20200339710A1 (en) 2020-10-29
US11673974B2 (en) 2023-06-13
US12227598B2 (en) 2025-02-18
MX2021012576A (es) 2021-11-12
KR20220005477A (ko) 2022-01-13

Similar Documents

Publication Publication Date Title
US12227598B2 (en) Glycophospholipid polymeric network and use thereof
US11845813B2 (en) Crosslinked polymeric network and use thereof
US11795320B2 (en) Grafted polymer and use thereof
US12371211B2 (en) Packaging solutions
CN121866208A (zh) 用于储存眼科装置的包装系统

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination