CN114054114A - Pipetting device - Google Patents
Pipetting device Download PDFInfo
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- CN114054114A CN114054114A CN202010748477.3A CN202010748477A CN114054114A CN 114054114 A CN114054114 A CN 114054114A CN 202010748477 A CN202010748477 A CN 202010748477A CN 114054114 A CN114054114 A CN 114054114A
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- suction head
- liquid
- pipetting
- liquid suction
- tip
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0275—Interchangeable or disposable dispensing tips
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- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention discloses a liquid transfer device which comprises a liquid suction mechanism, wherein the liquid suction mechanism is provided with a liquid suction head, a liquid suction head is detachably arranged on the liquid suction head, and the liquid transfer device also comprises a suction head separation mechanism which is used for separating the liquid suction head from the liquid suction head. The liquid suction head on the liquid suction head can be automatically separated through the suction head separation mechanism, so that the liquid suction head is prevented from being separated by adopting a manual means, the automatic operation of the liquid transfer device can be completely realized, and the working efficiency of the liquid transfer device is increased.
Description
Technical Field
The invention relates to the field of biomedical equipment, in particular to a liquid transfer device.
Background
In the purification process of nucleotide of biomolecule, various liquids need to be transferred, which requires a liquid transfer device, and the liquid transfer device needs a liquid suction head to suck the liquid and transfer the sucked liquid to a predetermined position when transferring the liquid. To avoid cross contamination, a single fluid tip can only draw the same fluid. Since a plurality of liquids are required to be transferred during the purification of nucleotides from biomolecules, different liquids are transferred by a plurality of pipetting devices during one purification of nucleotides, or a liquid tip is manually removed from a pipetting device and replaced with another liquid tip after one liquid is transferred by the pipetting device.
At present, the nucleotide purification process of biomolecules is automated, and in order to implement the automated operation, the existing nucleotide purification equipment generally transfers different liquids by arranging a plurality of liquid transfer devices. The nucleotide purification equipment not only has complex structure, large occupied space and higher cost. And moreover, the liquid suction head needs to be replaced manually after one-time nucleotide purification, and because the requirement on the field environment for nucleotide purification is higher, strict protection and sterilization need to be carried out on operators, so that the efficiency of nucleotide purification is influenced, and the quality of nucleotide purification is possibly influenced due to the fact that the protection and sterilization are not strict.
Disclosure of Invention
The technical problem to be solved by the present invention is to overcome the above-mentioned defects in the prior art, and to provide a liquid transfer device capable of automatically detaching a liquid suction head.
The invention solves the technical problems through the following technical scheme:
the utility model provides a liquid-transfering device, liquid-transfering device includes imbibition mechanism, imbibition mechanism has the suction head, the overhead demountable installation of imbibition has the liquid suction head, liquid-transfering device still includes suction head disengagement mechanism, suction head disengagement mechanism be used for with the liquid suction head is followed the overhead break away from of imbibition.
In this scheme, adopt above-mentioned structural style, can break away from the overhead liquid suction head of imbibition automatically through suction head disengagement mechanism, avoid adopting artifical means to break away from liquid suction head, can realize completely that liquid-transfering device's automation mechanized operation has increased liquid-transfering device's work efficiency.
Preferably, the pipette tip detachment mechanism includes a detachment member provided on a side of the pipette tip away from the pipette tip, and the detachment member is movable relative to the pipette tip so that the pipette tip is moved in a direction of detaching from the pipette tip by an urging force of the detachment member.
In this scheme, adopt above-mentioned structural style, through breaking away from piece and the first relative motion of imbibition, make the piece of breaking away from exert the effort to the overhead liquid suction head of imbibition, break away from the liquid suction head.
Preferably, the sucker disengagement mechanism further comprises a first driving member, and the first driving member is used for driving the disengagement member or the sucker to switch between a first position and a second position;
in the first position, the release member does not obstruct the connection of the fluid tip to the fluid tip;
in the second position, the disengagement member can disengage the fluid tip from the fluid tip.
In the scheme, the structure is adopted, the driving piece is used for controlling the separation piece or the liquid suction head to move, so that the separation piece or the liquid suction head is switched between the first position and the second position, and when the separation piece or the liquid suction head is in the first position, the separation piece does not block the connection between the liquid suction head and the liquid suction head, namely the liquid suction head can be installed on the liquid suction head without being blocked; in the second position, the release member can release the liquid suction head from the liquid suction head, i.e., the release member can release the liquid suction head from the liquid suction head, and the external liquid suction head cannot be mounted on the liquid suction head.
Preferably, the sucker disengaging mechanism further comprises a resetting unit, and the resetting unit is used for enabling the disengaging member to return from the second position to the first position when the disengaging member does not act with external force;
or the resetting unit is used for enabling the liquid suction head to return to the first position from the second position.
In this scheme, adopt above-mentioned structural style, can make after the piece that breaks away from the liquid suction head after using on the liquid suction head, do not hinder new liquid suction head installation.
Preferably, the suction head separation mechanism further comprises a guide seat and a guide rod, the guide seat is arranged between the first driving piece and the separation piece, the guide rod penetrates through the guide seat and can move in the guide seat, one end of the guide rod is connected to the separation piece, and the other end of the guide rod is connected to the first driving piece.
In this scheme, adopt above-mentioned structural style, the guide bar is in addition to providing power for the separation piece, still plays the effect of direction for the separation piece can accurately break away from the liquid suction head.
Preferably, the reset unit comprises a spring, and the spring is sleeved on the guide rod;
one end of the spring is fixed on the guide seat, and the other end of the spring is connected with the first driving piece;
or one end of the spring is fixed on the guide seat, and the other end of the spring is connected with the disengaging piece.
In this scheme, adopt above-mentioned structural style, utilize the spring to contract back the power and reset the separator, simple structure, it is with low costs.
Preferably, the imbibition mechanism includes a imbibition assembly, the imbibition assembly includes a cylinder body and a piston rod, the cylinder body is installed relative to one end of the piston rod the imbibition head, the imbibition head with the inner cavity of the cylinder body communicates.
In this scheme, adopt above-mentioned structural style, through the motion of piston rod for form negative pressure or malleation in the cylinder body, with this liquid is inhaled or is discharged through the imbibition head.
Preferably, the liquid suction mechanism further comprises a second driving member, and the second driving member is used for driving the piston rod to move in the cylinder body, so that the liquid suction head sucks or discharges liquid.
Preferably, the second driving member includes a stepping motor and a screw rod, the screw rod is connected to the piston rod, and the stepping motor is configured to drive the screw rod to drive the piston rod to move.
In this scheme, adopt above-mentioned structural style, through the motion of step motor control piston rod, not only control is accurate, still does benefit to and carries out automated operation.
Preferably, the wicking assembly is plural in number.
In this scheme, adopt above-mentioned structural style, can absorb multiunit liquid simultaneously, improve work efficiency.
Preferably, the piston rods of a plurality of the pipetting assemblies are fixed on the same connecting pressing plate, and the second driving member drives the piston rods through the connecting pressing plate.
In this scheme, adopt above-mentioned structural style, not only can just can control a plurality of imbibition subassemblies through a step motor, practice thrift the cost, can also carry out the synchronization operation to a plurality of imbibition subassemblies, avoid the error that produces of the same group imbibition subassembly when moving the liquid, increase testing result's accuracy.
Preferably, the pipetting device further comprises a mounting base having a mounting surface on which the pipetting mechanism and the pipette tip detachment mechanism are mounted.
Preferably, the pipetting device further comprises a lifting mechanism, and the mounting seat is fixed on the lifting mechanism and can move along with the lifting mechanism in the vertical direction.
In this scheme, adopt above-mentioned structural style, through the lift of elevating system control mount pad, not only can utilize the downward movement installation liquid suction head of imbibition mechanism, can also control liquid suction head and reciprocate, be convenient for absorb and discharge liquid.
Preferably, the lifting mechanism includes a third driving member, a screw rod and a nut, the nut is fixed on the mounting seat on a side opposite to the mounting surface, the screw rod is disposed through the nut, and the third driving member is configured to drive the screw rod to rotate so that the nut drives the mounting seat to move along an axial direction of the screw rod.
On the basis of the common knowledge in the field, the above preferred conditions can be combined randomly to obtain the preferred embodiments of the invention.
The positive progress effects of the invention are as follows: the liquid transfer device can automatically separate the liquid suction head on the liquid suction head through the suction head separation mechanism, avoids manual means for separating the liquid suction head, can completely realize the automatic operation of the liquid transfer device, and increases the working efficiency of the liquid transfer device.
Drawings
FIG. 1 is a schematic view of a pipetting device according to a preferred embodiment of the invention.
FIG. 2 is a schematic view of another perspective of the pipetting device in a preferred embodiment of the invention.
FIG. 3 is a front view of the pipetting device in a preferred embodiment of the invention.
FIG. 4 is a cross-sectional view of a pipetting device in a preferred embodiment of the invention.
FIG. 5 is a schematic view of the structure of the pipetting mechanism of the pipetting device in a preferred embodiment of the invention.
FIG. 6 is a schematic structural view of the lifting mechanism of the pipetting device in the preferred embodiment of the invention.
Description of reference numerals:
Disengaging member 201
Piston rod 213
Connecting pressure plate 214
Fixing plate 218
Second stepping motor 221
Bearing seat 223
First photovoltaic device 231
First photoelectric barrier 232
Second photovoltaic device 233
Second photovoltaic separator 234
Detailed Description
The invention is further illustrated by the following examples, which are not intended to limit the scope of the invention.
As shown in fig. 1-6, the liquid transfer device 200 of the present embodiment includes a liquid suction mechanism, the liquid suction mechanism has a liquid suction head 211, a liquid suction head 10 is detachably mounted on the liquid suction head 211, wherein the liquid suction head 211 has a plug, the liquid suction head 10 has a corresponding plug hole, and the liquid suction head 10 and the liquid suction head 211 can be fixed in a plug-in manner under the action of external force and can be separated under the action of external force. The pipetting device 200 further comprises a tip detachment mechanism for detaching the liquid tip 10 from the pipetting tip 211. The liquid-transfering device 200 can automatically separate the liquid suction head 10 on the liquid suction head 211 through the suction head separation mechanism, thereby avoiding the manual means from separating from the liquid suction head 10, completely realizing the automatic operation of the liquid-transfering device 200 and increasing the work efficiency of the liquid-transfering device 200.
Referring to fig. 1-4, in this embodiment, the pipetting mechanism and the tip detachment mechanism are mounted on a mounting surface of the first mount 210. As shown in fig. 4, the liquid suction mechanism includes a liquid suction assembly including a cylinder 212 having an inner cavity and a piston rod 213, a liquid suction head 211 is mounted on one end of the cylinder 212 opposite to the piston rod 213, and the liquid suction head 211 communicates with the inner cavity of the cylinder 212. By the movement of the piston rod 213, a negative pressure or a positive pressure is formed in the cylinder 212, whereby a liquid is sucked or discharged through the liquid suction head 10 on the liquid suction head 211.
In this embodiment, the movement of the piston rod 213 is controlled by the first stepping motor 216 and the first screw 215, the first screw 215 is connected to the piston rod 213, and the first stepping motor 216 is used to drive the first screw 215 to move the piston rod 213, so that the liquid suction head 10 on the liquid suction head 211 sucks or discharges liquid. The movement of the piston rod 213 is controlled by the first stepping motor 216, which not only controls precisely, but also facilitates automatic operation.
Of course, in other embodiments, the piston rod 213 may be controlled to move by other driving mechanisms, such as a pneumatic or hydraulic telescopic mechanism or other types of motors.
In order to improve work efficiency, can absorb multiunit liquid simultaneously, this imbibition mechanism has set up a plurality of imbibition subassemblies, and in this embodiment, imbibition subassembly has four, and four imbibition subassemblies's piston rod 213 is connected with first screw rod 215 through same connecting pressing plate 214, and the reciprocating of first screw rod 215 can drive four piston rods 213 simultaneously and remove, realizes four imbibition subassemblies imbibition or flowing back simultaneously. Fix the piston rod 213 of a plurality of imbibition subassemblies on same connection clamp plate 214, can just can control a plurality of imbibition subassemblies through a step motor, practice thrift the cost, can also carry out the synchronization operation to a plurality of imbibition subassemblies, avoid the same group imbibition subassembly to produce the error when moving the liquid, increase testing result's accuracy.
In other embodiments, the number of the liquid absorbing components can be set according to requirements, and can be one or more.
As shown in fig. 1 to 3, in this embodiment, in order to ensure the stability of the liquid suction mechanism during operation, both ends of the cylinder 212 of the liquid suction assembly are fixed to the first mounting base 210 by a fixing base 217 and a fixing plate 218, respectively. Of course, in other embodiments, the wicking assembly may be secured by only one securing device.
In this embodiment, as shown in FIGS. 1 to 3, the tip detachment mechanism includes a detachment member 201, the detachment member 201 is provided on a side of the pipette head 211 remote from the liquid pipette head 10, and the detachment member 201 is movable relative to the pipette head 211 so that the liquid pipette head 10 is moved in a direction to detach the pipette head 211 by the force of the detachment member 201. By the relative movement of the detaching member 201 and the liquid suction head 211, the detaching member 201 applies a force to the liquid suction head 10 on the liquid suction head 211, and the liquid suction head 10 is detached from the liquid suction head 211.
Wherein, break away from piece 201 and be the bar shaped plate, set up 4 through-holes that correspond with the imbibition head 211 of imbibition subassembly on the bar shaped plate, the internal diameter of this through-hole is greater than the external diameter of imbibition head 211 and is less than the tip external diameter of liquid suction head 10 and the imbibition head 211 link.
In this embodiment, the pipette head detachment mechanism further comprises a first driving member for driving the detachment member 201 to switch between a first position and a second position, in which the pipette head 211 is in a fixed position with respect to the first mounting base 210; in the first position, the release member 201 does not obstruct the connection of the liquid suction head 10 to the liquid suction head 211; in the second position, the disengaging member 201 can disengage the fluid-aspirating head 10 from the fluid-aspirating head 211.
Switching the release member 201 between the first position and the second position by controlling the movement of the release member 201, and allowing the release member 201 to be in the first position without the release member 201 obstructing the connection of the liquid suction head 10 to the liquid suction head 211, i.e., without the liquid suction head 10 being mounted on the liquid suction head 211; in the second position, the detaching member 201 can detach the liquid suction head 10 from the liquid suction head 211, that is, the detaching member 201 can detach the liquid suction head 10 from the liquid suction head 211, and the external liquid suction head 10 cannot be attached to the liquid suction head 211.
Of course, in other embodiments, the release member 201 may be in a fixed position relative to the first mounting seat 210, and the liquid suction head 211 may be switched between a first position and a second position relative to the release member 201; in the first position, the release member 201 does not obstruct the connection of the liquid suction head 10 to the liquid suction head 211; in the second position, the disengaging member 201 can disengage the fluid-aspirating head 10 from the fluid-aspirating head 211.
The suction head separation mechanism further comprises a guide seat and a guide rod 202, the guide seat is arranged between the first driving piece and the separation piece 201, the guide rod 202 penetrates through the guide seat and can move in the guide seat, one end of the guide rod 202 is connected to the separation piece 201, and the other end of the guide rod 202 is connected to the first driving piece. The guide bar 202, in addition to providing power to the detachment member 201, also acts as a guide so that the detachment member 201 can accurately detach the fluid-dispensing tip 10.
In this embodiment, the guide seats of the same side guide rod 202 include a first guide seat 203 and a second guide seat 206, which are respectively located at the ends of the fixing plate 218 and the fixing seat 217, the first guide seat 203 and the fixing plate 218 are independently disposed, and the second guide seat 206 and the fixing seat 217 are integrally formed.
In other embodiments, two guide seats of the same side of the guide rod 202 are respectively located at the upper and lower ends of the guide rod 202, and are independently arranged with the fixed seat 217 and the fixed plate 218 or are integrally formed; alternatively, only one guide seat of the same guide bar 202 is located in the middle of the guide bar 202.
Specifically, referring to fig. 1-3, in this embodiment, the first driving element is a driving plate 204 disposed on the lower side of the connecting pressing plate 214, the driving plate 204 is a strip-shaped plate structure, two ends of the driving plate 204 are respectively fixedly connected to two ends of the detaching element 201 through the guiding rod 202, the connecting pressing plate 214 moves downward under the driving of the first stepping motor 216, so that the connecting pressing plate 214 can press against the driving plate 204, the driving plate 204 moves downward so that the guiding rod 202 drives the detaching element 201 to move toward one side of the liquid suction head 10, and since the inner diameter of the through hole on the detaching element 201 is smaller than the outer diameter of the end of the connecting end of the liquid suction head 10, the liquid suction head 10 can be detached from the liquid suction head 211. In the embodiment, the driving plate 204 is driven by the connecting pressing plate 214 to control the disengaging part 201 to move, and an additional driving mechanism is not required to drive the disengaging part 201, so that the structure is simplified, and the cost is reduced.
Of course, in other embodiments, the disengaging member 201 may be controlled to move by other types of driving mechanisms, such as, for example, a pneumatic or hydraulic retracting mechanism, or a motor, which will not be described in detail herein.
When the connection pressing plate 214 is at the initial position, the connection pressing plate 214 does not drive the piston rod 213, and the liquid suction and discharge of the liquid suction head 211 are performed, and the release member 201 is at the first position where it does not obstruct the connection of the liquid suction head 10 and the liquid suction head 211. Since the first stepping motor 216 controls not only the suction and discharge of the suction head 211 but also the movement of the release member 201 in a direct or indirect manner, the first stepping motor 216 controls the following four-directional movement strokes of the connecting pressing plate 214 with respect to the initial position of the connecting pressing plate 214 by the first screw 215.
When the liquid absorption head 211 starts absorbing liquid, the first stepping motor 216 drives the connecting pressing plate 214 to drive the piston rod 213 to move towards the side far away from the liquid absorption head 211, and stops moving after absorbing predetermined liquid, which is a first moving stroke; when the liquid suction head 211 starts to discharge liquid, the first stepping motor 216 drives the connecting pressing plate 214 to move in the direction of returning to the initial position, and at this time, the piston rod 213 can discharge the sucked liquid, which is a second moving stroke; when the liquid suction head 10 needs to be separated, the first stepping motor 216 drives the connecting pressing plate 214 to move from the initial position to the side close to the liquid suction head 211, the connecting pressing plate 214 can be pressed against the driving plate 204, and then the driving plate 204 can drive the separating part 201 to move, so that the separating part 201 separates the liquid suction head 10, which is a third moving stroke; after the fluid tip 10 is disengaged, the first stepper motor 216 drives the linkage plate 214 back to the initial position, which is a fourth stroke of movement.
In the present embodiment, the drive plate 204 and the connecting platen 214 are provided separately. After the connecting pressing plate 214 is shifted from the third moving stroke to the fourth moving stroke, the connecting pressing plate 214 does not apply a force to the driving member, so that the separating member 201 is again located at the first position where it does not obstruct the connection of the liquid suction head 10 to the liquid suction head 211, and a new liquid suction head 10 can be easily mounted for the next pipetting operation.
In this embodiment, the reset unit is provided to return the detaching element 201 from the second position to the first position when the detaching element 201 has no external force. Specifically, referring to fig. 1-3, the reset unit of the present embodiment is a spring 205, and the spring 205 is sleeved on the guide rod 202; one end of the spring 205 is fixed to the first guide holder 203, and the other end of the spring 205 is connected to the driving plate 204. The driving plate 204 is reset by the retraction force of the spring 205, so that the disengaging member 201 returns to the first position, and the advantages of simple structure, low cost and the like are achieved.
In other embodiments, one end of the spring 205 may be fixed to the second guide base 206, and the other end of the spring 205 may be connected to the release member 201.
Alternatively, in other embodiments, the reset unit may be used in conjunction with the disengagement member 201 when it is driven by a pneumatic or hydraulic telescoping mechanism, or by an electric motor.
In other embodiments, the driving plate 204 and the connecting pressing plate 214 can be fixedly connected, and at this time, the connecting pressing plate 214 can drive the disengaging member 201 to reset, and a reset unit is not required to be separately provided, however, it should be noted that the maximum stroke range of the connecting pressing plate 214 when driving the piston rod 213 to suck liquid cannot be larger than the movable stroke of the disengaging member 201 on the liquid sucking head 211, otherwise, the disengaging member 201 can touch the fixing seat 217 to damage the pipetting device 200, or other unpredictable conditions occur.
Alternatively, in other embodiments, when the detaching element 201 is in a fixed position relative to the first mounting seat 210 and the pipette head 211 is switched between the first position and the second position relative to the detaching element 201, the resetting unit is used to return the pipette head 211 from the second position to the first position, and the arrangement of the resetting unit is not described herein again.
As shown in fig. 1 to 4 and fig. 6, in the present embodiment, the pipetting device 200 further includes an elevating mechanism by which the pipetting mechanism is controlled to move up and down. One surface of the first mounting base 210 opposite to the mounting surface is fixed on the lifting mechanism, so that the first mounting base 210 moves in the vertical direction along with the lifting mechanism. The lifting mechanism controls the first mounting base 210 to lift, so that the liquid suction head 10 can be mounted by downward moving and inserting of the liquid suction mechanism, and the liquid suction head 10 can be controlled to move up and down, thereby being convenient for sucking and discharging liquid.
Specifically, please refer to fig. 5-6, wherein the lifting mechanism includes a second stepping motor 221, a second screw 225, a nut 226, and a second mounting base 220, the second mounting base 220 is provided with the second stepping motor 221 and a bearing seat 223, the nut 226 is fixed on a side surface of the first mounting base 210 opposite to the mounting surface through a nut fixing seat 227, a lower end of the second screw 225 passes through the nut 226, an upper end of the second screw 225 passes through a bearing in the bearing seat 223 and is fixedly connected with an output shaft of the second stepping motor 221 through a coupling 222, and the second stepping motor 221 drives the second screw 225 to rotate so that the nut 226 drives the first mounting base 210 to move along an axial direction of the second screw 225.
The first mounting base 210 and the second mounting base 220 are respectively provided with a first sliding block 219 and a second sliding block 224, and the first sliding block 219 and the second sliding block 224 can slide in a matched manner, so that the stability of the first mounting base 210 during up-down movement under the driving of the lifting mechanism is ensured.
In this embodiment, in order to avoid the damage to the pipetting module and the like caused by the excessive upward movement of the piston rod 213 due to the erroneous setting of the program, a limit mechanism is further provided to limit the maximum movement stroke of the piston rod 213 at the time of pipetting, and as shown in fig. 1 and 3, the first mount 210 is provided with the first photoelectric device 231, the movable platen is provided with the first photoelectric partition 232, and when the first photoelectric partition 232 cuts off the signal of the first photoelectric device 231, the first stepping motor 216 stops operating.
In other embodiments, in order to avoid the connecting pressing plate 214 moving downwards to press against the disengaging member 201, and the lower end of the piston rod 213 moving excessively to damage the pipetting assembly, the photoelectric assembly may be further arranged to control the maximum moving stroke of the connecting pressing plate 214 driving the disengaging member 201 to move.
In this embodiment, in order to avoid excessive upward movement of the first mounting base 210 controlled by the lifting mechanism due to a program setting error, a limiting mechanism is further provided to limit the maximum movement stroke of the first mounting base 210 during the lifting process, as shown in fig. 2, the second mounting base 220 is provided with a second photoelectric device 233, the first mounting base 210 is provided with a second photoelectric partition 234, and when the second photoelectric partition 234 cuts off a signal of the second photoelectric device 233, the second stepping motor 221 stops working, and the second screw 225 no longer drives the first mounting base 210 to lift.
Of course, in other embodiments, in order to avoid the occurrence of excessive downward movement of the first mounting seat 210 controlled by the lifting mechanism, the photovoltaic module may be further configured to limit the maximum movement stroke of the first mounting seat 210 during the descending process.
While specific embodiments of the invention have been described above, it will be appreciated by those skilled in the art that this is by way of example only, and that the scope of the invention is defined by the appended claims. Various changes and modifications to these embodiments may be made by those skilled in the art without departing from the spirit and scope of the invention, and these changes and modifications are within the scope of the invention.
Claims (14)
1. The utility model provides a liquid-transfering device, liquid-transfering device includes imbibition mechanism, imbibition mechanism has the suction head, the overhead demountable installation of imbibition has the liquid suction head, its characterized in that, liquid-transfering device still includes suction head disengagement mechanism, suction head disengagement mechanism be used for with the liquid suction head is followed the overhead separation of imbibition.
2. The pipette device according to claim 1, wherein the tip detachment mechanism includes a detachment member provided on a side of the pipette head away from the liquid tip, the detachment member being movable relative to the pipette head so that the liquid tip is moved in a direction of detaching from the pipette head by a force of the detachment member.
3. The pipette device according to claim 2, wherein the tip detachment mechanism further comprises a first driving member for driving the detachment member or the pipette tip to switch between the first position and the second position;
in the first position, the release member does not obstruct the connection of the fluid tip to the fluid tip;
in the second position, the disengagement member can disengage the fluid tip from the fluid tip.
4. The pipette device according to claim 3, wherein the tip detachment mechanism further comprises a reset unit for returning the detachment member from the second position to the first position when the detachment member is not applied with an external force;
or the resetting unit is used for enabling the liquid suction head to return to the first position from the second position.
5. The pipette device according to claim 4, wherein the tip detachment mechanism further comprises a guide holder provided between the first driving member and the detachment member, and a guide rod inserted through the guide holder and movable in the guide holder, one end of the guide rod being connected to the detachment member, and the other end of the guide rod being connected to the first driving member.
6. Pipetting device according to claim 5, characterized in that the reset unit comprises a spring which is arranged around the guide rod;
one end of the spring is fixed on the guide seat, and the other end of the spring is connected with the first driving piece;
or one end of the spring is fixed on the guide seat, and the other end of the spring is connected with the disengaging piece.
7. The pipetting device of claim 1, wherein the pipetting mechanism comprises a pipetting assembly including a cylinder having an interior chamber and a piston rod, the cylinder having an end opposite the piston rod mounted with the pipetting head, the pipetting head communicating with the interior chamber of the cylinder.
8. The pipetting device of claim 7, wherein the pipetting mechanism further comprises a second drive for moving the piston rod within the cylinder to cause the pipetting head to aspirate or expel liquid.
9. A pipetting device as recited in claim 8 wherein the second drive member comprises a stepper motor and a screw, the screw being connected to the piston rod, the stepper motor being adapted to drive the screw to move the piston rod.
10. A pipetting device as recited in claim 8 wherein the pipetting assembly is plural in number.
11. The pipetting device of claim 10, wherein the piston rods of a plurality of the pipetting assemblies are secured to the same connecting pressure plate, and the second drive member drives a plurality of the piston rods through the connecting pressure plate.
12. The pipette device according to claim 1, wherein the pipette device further comprises a mount having a mounting surface on which the pipetting mechanism and the tip detachment mechanism are mounted.
13. The pipette device according to claim 12, wherein the pipette device further comprises an elevating mechanism, and the mount is fixed to the elevating mechanism and is movable in a vertical direction with the elevating mechanism.
14. The pipette device according to claim 13, wherein the elevating mechanism includes a third driving member, a screw rod and a nut, the nut is fixed to a side of the mounting base opposite to the mounting surface, the screw rod is passed through the nut, and the third driving member is configured to drive the screw rod to rotate so that the nut drives the mounting base to move in an axial direction of the screw rod.
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CN202010748477.3A CN114054114A (en) | 2020-07-30 | 2020-07-30 | Pipetting device |
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CN202010748477.3A CN114054114A (en) | 2020-07-30 | 2020-07-30 | Pipetting device |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2024119864A1 (en) * | 2022-12-08 | 2024-06-13 | 深圳晶泰科技有限公司 | Pipette and pipetting device |
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Publication number | Priority date | Publication date | Assignee | Title |
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WO2024119864A1 (en) * | 2022-12-08 | 2024-06-13 | 深圳晶泰科技有限公司 | Pipette and pipetting device |
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