CN114047349A - Cleaning water temperature control device and control method for full-automatic biochemical analyzer - Google Patents
Cleaning water temperature control device and control method for full-automatic biochemical analyzer Download PDFInfo
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- CN114047349A CN114047349A CN202111298205.9A CN202111298205A CN114047349A CN 114047349 A CN114047349 A CN 114047349A CN 202111298205 A CN202111298205 A CN 202111298205A CN 114047349 A CN114047349 A CN 114047349A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00346—Heating or cooling arrangements
Abstract
The invention discloses a cleaning water temperature control device of a full-automatic biochemical analyzer and a control method thereof, and the cleaning water temperature control device comprises a water storage container S01, wherein the water storage container S01 is connected with a water inlet valve V01 and a main water supply pump P01, the water inlet valve V01 is connected with a water source to form a water source supply channel, the main water supply pump P01 is connected with a primary heating container and a secondary heating container, the primary heating container is communicated with the water storage container S01, and the secondary heating container is communicated with a reaction cup cleaning needle. The control device and the control method can realize constant temperature of the reaction system in the reaction process of the biochemical analyzer, the cleaning water in the reaction cup does not fluctuate periodically, the temperature difference between the reaction cups is reduced, the deviation from a normal result is avoided, the whole control method is simple and convenient, and the cleaning quality and efficiency are ensured.
Description
Technical Field
The invention relates to the technical field of biochemical analyzer cleaning, in particular to a full-automatic biochemical analyzer cleaning water temperature control device and a control method.
Background
The reaction cup of the full-automatic biochemical analyzer needs to be completely cleaned before a sample is tested. Generally, the more times the same cuvette is cleaned, the less residue will be left in the cuvette and the more complete the cleaning will be. However, the temperature fluctuation of the cleaning water of the existing reaction cups is large, the temperature difference among the reaction cups is large due to multiple cleaning, the decontamination capability is weak, the reaction system needs to be constant in the reaction process of the biochemical analyzer, and the temperature difference among the reaction cups is too large, so that the normal result is deviated. The current temperature control technology can cause the periodical fluctuation of the reaction cup cleaning water or the control method is complicated, which can seriously affect the cleaning quality and efficiency and cause the unstable clinical test result.
Disclosure of Invention
The invention aims to overcome the problems in the prior art and provides a full-automatic biochemical analyzer cleaning water temperature control device and a control method, the control device and the control method can realize constant temperature of a reaction system in the reaction process of the biochemical analyzer, periodic fluctuation of the cleaning water in reaction cups is avoided, the temperature difference between the reaction cups is reduced, deviation from a normal result is avoided, and the whole control method is simple and convenient to operate.
The purpose of the invention is mainly realized by the following technical scheme:
the reaction cup of the current full-automatic biochemical analyzer needs to be completely cleaned before a sample is tested. The more times the same reaction cup is cleaned, the less residue in the reaction cup is left, and the more complete the cleaning is. However, the temperature fluctuation of the cleaning water of the existing reaction cups is large, the temperature difference between the reaction cups is large due to multiple times of cleaning, the decontamination capability is weak, the reaction system needs to be kept at a constant temperature in the reaction process of the biochemical analyzer, the temperature difference between the reaction cups is too large, a normal result is deviated, and the problem of the cleaning water temperature fluctuation in the test process of the biochemical analyzer is solved. The scheme designs a full-automatic biochemical analyzer cleaning water temperature control device which comprises a water storage container S01, wherein the water storage container S01 is connected with a water inlet valve V01 and a main water feed pump P01, the water inlet valve V01 is connected with a water source, the main water feed pump P01 is connected with a first-stage heating container and a second-stage heating container, the first-stage heating container is communicated with the water storage container S01, and the second-stage heating container is communicated with a reaction cup cleaning needle. Through this kind of controlling means, through branch heating, can realize thermostatic control, can not appear periodic fluctuation at the reaction cup washing water, whole controlling means simple structure.
Further, a liquid level detection switch and a temperature sensor are arranged in the water storage container S01, and the liquid level detection switch is connected with the water inlet valve V01; and a temperature sensor is arranged between the secondary heating container and the reaction cup cleaning needle, and the temperature sensor is simultaneously connected with the secondary heating container and the reaction cup cleaning needle. Through the liquid level detection switch and the temperature sensor that set up, can realize that water level detects and temperature detect, realized accurate control, liquid level detection switch and temperature sensor all are current parts, can directly purchase on the market. The water inlet valve V01 is negatively fed back and regulated by a liquid level detection switch, and the liquid level detection switch is in signal connection with the water inlet valve V01. Temperature sensor detects second grade heating container exit temperature, and this local temperature detection numerical value just can satisfy this scheme needs.
The biochemical analyzer reactant has high requirement on the process temperature, and the large temperature fluctuation can cause the fluctuation of the clinical test result. The device was developed to increase the stability of the clinical test results. Two technologies are adopted to realize the first technology, namely, the heating power of a secondary heating device is determined by a single temperature sensor close to an outlet and arranged in a secondary heating container; the second is that temperature sensors are arranged at the inlet and the outlet of the secondary heating container, and the heating power of the secondary heating device is determined by a software algorithm.
The existing cleaning temperature control technology comprises the following steps: after water enters the whole machine, pure water is stored in the water storage container, the primary heating device circularly heats the water storage container, and part of the pure water in the water storage container is pumped to the secondary heating container.
The disadvantages of the first technique are: when the inlet temperature of the secondary heating container is low (corresponding to the water storage container just filled with water), the sensor senses low temperature, but the secondary heating device cannot instantly reach the desired temperature, and only continuously outputs the low temperature with high power. When the water temperature is too high, the sensor can reduce or cut off the output of the secondary heating device, when the water storage container is filled with water again, the inlet temperature of the secondary heating container is reduced, the temperature sensor does not sense the temperature change, the output of the secondary heating device cannot be increased immediately, the water temperature at the section is reduced to be lower than the target temperature, and the reaction cup washing water is periodically fluctuated due to the cyclic reciprocation.
The disadvantages of the second technique are: although the temperature fluctuation of the cleaning water of the reaction cup can be reduced to a certain extent, the output of the heating container needs to be set according to different inlet and outlet temperatures, and the control algorithm is complex.
In order to solve the problems, the scheme designs a method for controlling the temperature of cleaning water of a full-automatic biochemical analyzer, which comprises the following steps:
(1) setting water inlet flow Q1 at a water source to be greater than cleaning needle flow Q3, outputting a feedback signal V0 when the liquid level detection switch detects that the liquid level is not at a high level, opening a water inlet valve V01 until the liquid level detection switch detects that the liquid level is at the high level, outputting a feedback signal V1, closing the water inlet valve V01, and realizing constant water level control;
(2) during the instrument rewarming period, the flow Q2 on a branch circuit of the primary heating container is constant, the water level in the water storage container S01 is constant, the current time temperature of a temperature sensor in the water storage container S01 is T1, the target temperature of the sensor is T01, the fluctuation value is T02, when T1< (T01-T02), the primary heating container is output with full power K1, when (T01-T02) < T1< T01, the primary heating container is output with power K1 (T01-T1)/(T01-T02), when T1> T01, the primary heating container is closed, a water inlet valve V01 is opened, the liquid level is increased to an ultrahigh position for cooling, and K1 is a power temperature coefficient;
(3) after the temperature of water in the water storage container S01 is constant, the temperature of water at an inlet connected to the secondary heating container is constant, the flow rate at an outlet of the secondary heating container is constant, the temperature fluctuation of a sensor arranged in the secondary heating container is large, therefore, a temperature sensor is arranged at an outlet section of the secondary heating container, the target temperature of the sensor is T03 after the temperature T3 of the temperature sensor arranged at the outlet section of the secondary heating container is collected, when the T3 is less than T03, the output power of the secondary heating container is K2 ((T03-T1) + (T03-T3)), and when the T3> is equal to T03, the secondary heating container stops heating, wherein K2 is a power temperature coefficient.
By the control method, the constant temperature control of the water temperature can be realized, in addition, the periodic fluctuation can not occur in the control process, the deviation from the normal result can not occur, the whole control method is simple and convenient to operate, and the cleaning quality and the cleaning efficiency are ensured.
In conclusion, compared with the prior art, the invention has the following beneficial effects: the invention can realize the constant temperature control of the water temperature through a simple device and a simple algorithm, avoid the failure of temperature control under the condition of complex software control, and in the control process, the temperature can not generate periodic fluctuation and can not deviate from the normal result, the whole control method is simple and convenient to operate, and the cleaning quality and efficiency are ensured.
Drawings
The accompanying drawings, which are included to provide a further understanding of the embodiments of the invention and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the invention and together with the description serve to explain the principles of the invention. In the drawings:
FIG. 1 is a schematic flow chart of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to examples and accompanying drawings, and the exemplary embodiments and descriptions thereof are only used for explaining the present invention and are not meant to limit the present invention.
As shown in fig. 1, a hardware structure of a full-automatic biochemical analyzer cleaning water temperature control device includes a water storage container S01, the water storage container S01 is connected with a water inlet valve V01, pure water is connected to the water storage container S01 through a user-side ball valve by the water inlet valve V01, wherein the water inlet valve V01 is connected with a water source to form a water source supply channel, the water storage container S01 is connected with an inlet of a main water feed pump P01, an outlet of the main water feed pump P01 is divided into two branches, one branch is heated by a primary heating container and then flows back to the water storage container S01, the other branch is connected with a secondary heating container, an outlet of the secondary heating container is connected with a reaction cup cleaning needle, a temperature sensor is arranged between the outlet of the secondary heating container and the reaction cup cleaning needle, and the temperature sensor is simultaneously connected with the secondary heating container and the reaction cup cleaning needle. A liquid level detection switch and a temperature sensor are arranged in the water storage container S01, the liquid level detection switch is connected with the water inlet valve V01, and the liquid level detection switch is used for detecting the height position of liquid in the water storage container S01.
A method for controlling the temperature of cleaning water of a full-automatic biochemical analyzer comprises the following steps:
(1) firstly, setting water inlet flow Q1 at a water source and cleaning needle flow Q3, wherein the water inlet flow is larger than water consumption in unit time, so that the on-off of a water inlet valve V01 can be controlled through a high-level signal detected by a liquid level control switch to keep the liquid level in S01 constant, when the liquid level detected by the liquid level detection switch is not at the high level, a feedback signal V0 is output, a water inlet valve V01 is opened, and when the liquid level detected by the liquid level detection switch is at the high level, a feedback signal V1 is output, the water inlet valve V01 is closed, and the constant control of the water level is realized;
(2) during the instrument rewarming period, the flow Q2 on the branch circuit of the primary heating container is constant, the water level in the water storage container S01 is constant, the current time temperature of a temperature sensor in the water storage container S01 is T1, the target temperature of the sensor is T01, the fluctuation value is T02, and when T1< (T01-T02), the primary heating container outputs full power K1; when (T01-T02) < T1< T01, the primary heating container is output with power K1 (T01-T1)/(T01-T02), when T1> T01, the primary heating container is closed and output, the water inlet valve V01 is opened for T seconds, the liquid level rises to cool, the software compares the sizes of T1 and T01, if T1 is still larger than T01, the water inlet valve is opened again for T seconds, the sizes of T1 and T01 are compared again, if T1 is still larger than T01, the water inlet valve is opened again for T seconds until T1 is smaller than or equal to T01, when the water level rises to an ultrahigh position in the process, T1> T01, the heating is abnormal, and the whole machine stops running and reports;
(3) after the water temperature in the water storage container S01 is constant, the water temperature at the inlet connected to the secondary heating container is constant, the flow rate at the outlet of the secondary heating container is constant, the temperature fluctuation of a sensor arranged in the secondary heating container is large, therefore, a temperature sensor is arranged at the outlet section of the secondary heating container, the target temperature of the sensor is T03 after the temperature T3 of the temperature sensor arranged at the outlet section of the secondary heating container is collected, when the T3 is less than T03, the output power K2 of the secondary heating container ((T03-T1) + (T03-T3)), and when the T3> is equal to T03, the secondary heating container stops heating. Thus, a constant cleaning needle outlet temperature can be achieved by a simple algorithm.
The invention can realize the constant temperature control of the water temperature, and in the control process, the periodic fluctuation can not occur, the deviation from the normal result can not be generated, the whole control method is simple and convenient to operate, and the cleaning quality and the cleaning efficiency are ensured.
The above embodiments are provided to further explain the objects, technical solutions and advantages of the present invention in detail, it should be understood that the above embodiments are merely exemplary embodiments of the present invention and are not intended to limit the scope of the present invention, and any modifications, equivalents, improvements and the like made within the spirit and principle of the present invention should be included in the scope of the present invention.
Claims (4)
1. The utility model provides a full-automatic biochemical analyzer washs water temperature control device which characterized in that: the reaction cup cleaning device comprises a water storage container S01, wherein the water storage container S01 is connected with a water inlet valve V01 and a main water feed pump P01, the water inlet valve V01 is connected with a water source, the main water feed pump P01 is connected with a primary heating container and a secondary heating container, the primary heating container is communicated with the water storage container S01, and the secondary heating container is communicated with a reaction cup cleaning needle.
2. The apparatus for controlling the temperature of washing water of a full-automatic biochemical analyzer according to claim 1, wherein: a liquid level detection switch and a temperature sensor are arranged in the water storage container S01, and the liquid level detection switch is connected with the water inlet valve V01.
3. The apparatus for controlling the temperature of washing water of a full-automatic biochemical analyzer according to claim 1, wherein: and a temperature sensor is arranged between the secondary heating container and the reaction cup cleaning needle, and is simultaneously connected with the secondary heating container and the reaction cup cleaning needle.
4. A method for controlling the temperature of cleaning water of a full-automatic biochemical analyzer is characterized by comprising the following steps: the method comprises the following steps:
(1) setting water inlet flow Q1 at a water source to be greater than cleaning needle flow Q3, outputting a feedback signal V0 when the liquid level detection switch detects that the liquid level is not at a high level, opening a water inlet valve V01 until the liquid level detection switch detects that the liquid level is at the high level, outputting a feedback signal V1, closing the water inlet valve V01, and realizing constant water level control;
(2) during the instrument rewarming period, the flow Q2 on a branch circuit of the primary heating container is constant, the water level in the water storage container S01 is constant, the current time temperature of a temperature sensor in the water storage container S01 is T1, the target temperature of the sensor is T01, the fluctuation value is T02, when T1< (T01-T02), the primary heating container is output with full power K1, when (T01-T02) < T1< T01, the primary heating container is output with power K1 (T01-T1)/(T01-T02), when T1> T01, the primary heating container is closed, a water inlet valve V01 is opened, and the liquid level rises to an ultrahigh position to cool;
(3) after the water temperature in the water storage container S01 is constant, the water temperature at the inlet connected to the secondary heating container is constant, the flow rate at the outlet of the secondary heating container is constant, the temperature fluctuation of a sensor arranged in the secondary heating container is large, therefore, a temperature sensor is arranged at the outlet section of the secondary heating container, the target temperature of the sensor is T03 after the temperature T3 of the temperature sensor arranged at the outlet section of the secondary heating container is collected, when the T3 is less than T03, the output power K2 of the secondary heating container ((T03-T1) + (T03-T3)), and when the T3> is equal to T03, the secondary heating container stops heating.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111298205.9A CN114047349A (en) | 2021-11-04 | 2021-11-04 | Cleaning water temperature control device and control method for full-automatic biochemical analyzer |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202111298205.9A CN114047349A (en) | 2021-11-04 | 2021-11-04 | Cleaning water temperature control device and control method for full-automatic biochemical analyzer |
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| CN114047349A true CN114047349A (en) | 2022-02-15 |
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| CN202111298205.9A Pending CN114047349A (en) | 2021-11-04 | 2021-11-04 | Cleaning water temperature control device and control method for full-automatic biochemical analyzer |
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