CN114042197A - Device for adsorbing uremia by superfine fiber soft substance tows and using method thereof - Google Patents
Device for adsorbing uremia by superfine fiber soft substance tows and using method thereof Download PDFInfo
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- CN114042197A CN114042197A CN202111486417.XA CN202111486417A CN114042197A CN 114042197 A CN114042197 A CN 114042197A CN 202111486417 A CN202111486417 A CN 202111486417A CN 114042197 A CN114042197 A CN 114042197A
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- superfine fiber
- soft substance
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- silica gel
- peritoneal dialysis
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- 239000000126 substance Substances 0.000 title claims abstract description 63
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- 208000009852 uremia Diseases 0.000 title claims abstract description 25
- 238000000034 method Methods 0.000 title claims abstract description 15
- 238000000502 dialysis Methods 0.000 claims abstract description 63
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- 229910002027 silica gel Inorganic materials 0.000 claims abstract description 58
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims abstract description 14
- 239000004202 carbamide Substances 0.000 claims abstract description 14
- 239000000385 dialysis solution Substances 0.000 claims abstract description 13
- 238000001179 sorption measurement Methods 0.000 claims abstract description 6
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- 210000000683 abdominal cavity Anatomy 0.000 claims description 43
- 239000002699 waste material Substances 0.000 claims description 42
- 238000001802 infusion Methods 0.000 claims description 18
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- 239000000463 material Substances 0.000 claims description 10
- 230000010412 perfusion Effects 0.000 claims description 10
- 210000003200 peritoneal cavity Anatomy 0.000 claims description 10
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 8
- 229920000642 polymer Polymers 0.000 claims description 6
- 230000002503 metabolic effect Effects 0.000 claims description 5
- 239000003330 peritoneal dialysis fluid Substances 0.000 claims description 4
- 230000008569 process Effects 0.000 claims description 4
- 239000007779 soft material Substances 0.000 claims description 4
- 239000011787 zinc oxide Substances 0.000 claims description 4
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- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
- A61M1/282—Operational modes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
- A61M1/287—Dialysates therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- External Artificial Organs (AREA)
Abstract
The invention discloses a device for adsorbing uremia by superfine fiber soft substance tows and a using method thereof. The fiber surface of the superfine fiber soft substance filament bundle with a certain length can continuously adsorb substances such as urea in the peritoneal dialysis solution, thereby reducing the concentration of urea in the dialysis solution, the fiber bundle between the small silica gel balls can also be scattered, the adsorption efficiency of the filament bundle is increased, thereby keeping the lower concentration of urea in the dialysis solution for a longer time, leading toxins in blood to pass through the blood vessel wall under the driving of osmotic pressure and continuously transfer mass to the peritoneal dialysis solution, and greatly prolonging the service time of the dialysis solution, thereby achieving the aim of reducing the change frequency of the dialysis solution, further improving the service time of the dialysis solution, reducing the peritoneal dialysis frequency, and prolonging the beneficial effect of the peritoneal dialysis period.
Description
Technical Field
The invention relates to the field of clinical medical treatment, in particular to a dialysis device and a method used in peritoneal dialysis.
Background
Renal failure is a pathological state of renal failure of a human body, which can cause that the patient cannot excrete toxins in the body, and the electrolytes such as sodium, potassium, calcium and the like in the human body system are stable and balanced in acid and base. Early stage chronic renal failure can be treated by drugs, but when the condition deteriorates to a uremic state, a treatment method of hemodialysis or peritoneal dialysis is required for the life of the patient in addition to the kidney transplantation treatment.
Hemodialysis is to introduce the blood and dialysate of a patient into an extracorporeal dialysis device at the same time, remove excessive toxins and excessive water accumulated in the blood by using a semipermeable membrane of the dialysis device, supplement basic groups to correct acidosis, adjust electrolyte disorder, and replace the excretion function of the kidney. In the dialysis treatment process, small-molecule solutes and water can be rapidly removed by hemodialysis, but residual kidney functions can be rapidly lost by hemodialysis, and the hemodialysis has a large influence on in-vivo blood circulation, so that the hemodialysis is not suitable for people suffering from heart failure, poor blood vessel conditions, mental disorders and the like. Therefore, peritoneal dialysis is considered when the patient's peritoneal membrane is functioning well and not suitable for hemodialysis.
Peritoneal dialysis utilizes the peritoneum as the semipermeable membrane, injects the dialysate into the abdominal cavity through the peritoneal dialysis tube, removes toxins through the diffusion effect, corrects electrolyte and acid-base balance disorder, and achieves ultrafiltration dehydration through the osmosis principle (adding glucose into the dialysate to improve the osmotic pressure of the dialysate) to replace the excretion function of the kidney. Peritoneal dialysis compares in hemodialysis, and the dialysis process is carried out at home, can oneself or family members carry out peritoneal dialysis's manual operation, only need inject the dislysate into the peritoneal cavity through the peritoneal dialysis pipe, and dialysis equipment is simple relatively to it is better to patient's remaining renal function protection, and influence and the requirement to the cardiac function are less. Patients undergoing peritoneal dialysis, however, are confronted with long-term, high-frequency treatment. In contrast to 3-4 weekly treatments of hemodialysis, peritoneal dialysis is required daily, and in some cases 3-4 times a day, which seriously affects the normal life of the patient.
Therefore, how to reduce the frequency of peritoneal dialysis and prolong the period of peritoneal dialysis, which does not affect the normal life of the patient while ensuring the treatment effect of the patient, is a key problem to be solved by the current peritoneal dialysis treatment method.
Disclosure of Invention
Aiming at the defects of the prior peritoneal dialysis technology, the invention innovates the method and the device for peritoneal dialysis, introduces a superfine fiber soft substance tow into the abdominal cavity on the basis of the traditional gravity type peritoneal dialysis, the superfine fiber surface contains materials (such as zinc oxide particles) capable of adsorbing toxic substances such as urea and the like, continuously adsorbs the substances such as urea and the like in the dialysate, and reduces the concentration of the urea and the like in the dialysate, thereby keeping the dialysate at higher osmotic pressure for a longer time, prolonging the service time of the dialysate and reducing the dialysis frequency.
The technical scheme of the invention is as follows: the utility model provides a device of soft material silk bundle of superfine fiber adsorbs uremia, includes peritoneal dialysis transfusion system of changing, peritoneal dialysis pipe, abdominal cavity interface, iodophor cap and the soft material silk bundle of superfine fiber, and peritoneal dialysis transfusion system of changing includes dialysate bag, transfer line, sealing plug, waste liquid bag, waste liquid pipe and tee bend ball valve. The dialysate bag is well sealed, the dialysate is prevented from being polluted by the external environment, the sealing plug is positioned at the outlet of the dialysate bag, the dialysate bag is sealed, the sealing plug is broken, the dialysate can flow into the perfusion tube, the three-way ball valve is connected to the tail end of the perfusion tube, and meanwhile, the three-way ball valve can be connected with an abdominal cavity interface and a waste liquid tube to control the connection of three pipelines. The waste liquid pipe end connects the waste liquid bag, and the waste liquid bag requires to be sealed well, can not make the waste liquid flow into external environment, the polluted environment. The abdominal cavity joint connected with the three-way ball valve is made of titanium alloy materials and has the advantages of high strength, corrosion resistance and no magnetism, one end outside the peritoneal dialysis tube body is connected with the abdominal cavity joint, the other end is placed in the abdominal cavity through a minimally invasive surgery, and the peritoneal dialysis tube is made of polymers with good biocompatibility. The end part of the transfusion tube is provided with a superfine fiber soft substance tow storage structure, the section of the structure is three quarters of a circle, and the superfine fiber soft substance tow can be clamped in the structure. The superfine fiber soft substance tow consists of superfine fibers, a supporting wire, a plurality of small silica gel balls and a large silica gel ball, wherein the diameter of the large silica gel ball is slightly larger than that of the abdominal cavity joint. When the superfine fiber soft material tows flow along with the peritoneal dialysis solution, the large silica gel ball is clamped at the peritoneal dialysis interface, and the small silica gel ball flows into the abdominal cavity along with the peritoneal dialysis solution. The iodophor cap is connected with the abdominal cavity interface, and can completely cover the large silica gel ball to ensure sealing. The fiber is prepared from a polymer with biological safety, the surface of the fiber contains an adsorption material of metabolic wastes such as urea and the like, and the fiber constrained among the small silica gel balls continuously adsorbs the metabolic wastes in the dialysate in the abdominal cavity, so that the uremia in the dialysate in the abdominal cavity is always kept at a lower concentration, the service life of the dialysate is greatly prolonged, and therefore, the change frequency of the dialysate is reduced, the peritoneal dialysis frequency is reduced, and the peritoneal dialysis period is prolonged.
The raw materials of the fiber tows in the device for adsorbing uremia by the superfine fiber soft substance tows are blends of polymers with biosafety and materials capable of adsorbing metabolic wastes such as zinc oxide, and the blends are used for preparing superfine fibers by safe and reliable processing methods such as melt differential electrostatic spinning and the like, so that fiber matrixes and adsorbing material particles are reliably combined and do not fall off. The length of the tows is about 1.5-3 times of that of the peritoneal dialysis catheter, so that the tows in the peritoneal cavity have enough length when the large silica gel ball is clamped at the abdominal cavity interface, the area of the fiber in the peritoneal cavity is increased, and the efficiency of the fiber bundles for absorbing metabolic wastes is increased. The middle section of the fiber bundle is restrained by a plurality of small silica gel balls, so that the fiber bundle cannot be wound when flowing or soaking in dialysate, the smooth entering of the fiber bundle into the abdominal cavity is ensured, and the fiber bundle can be unfolded in the abdominal cavity. The surface of the large silica gel ball is provided with the holes, so that the large silica gel ball is conveniently clamped by tweezers, and the whole tow is conveniently taken out of the abdominal cavity. The middle of the superfine fiber tows contains supporting wires with the diameter of 100-300 microns, the supporting wires are made of the same material as the superfine fibers, and the supporting wires can be filaments or yarns, so that when the superfine fiber soft substance tows are taken out of the abdominal cavity, the superfine fiber soft substance tows can bear larger breaking force, and the tows cannot break in the abdominal cavity. The supporting wires can also be made of other materials with biosafety and higher strength, and the diameter is determined according to the tensile force required to be borne.
The invention relates to a using method of a device for adsorbing uremia by using superfine fiber soft substance tows, wherein one end of an abdominal penetrating pipe is placed into an abdominal cavity through a minimally invasive surgery, one end outside the peritoneal dialysis tube body is connected with the peritoneal cavity joint, the sealing plug is broken to ensure that the dialysate flows out from the dialysate bag, the three-way ball valve is rotated to ensure that the peritoneal dialysis tube is communicated with the perfusion tube, when stable dialysate flow exists in the infusion tube, the storage structure on the infusion tube is extruded, the small silica gel balls are sequentially extruded into the infusion tube from the tail end of the infusion tube, and each small silica gel ball is extruded, when the tows among the small silica gel balls are completely unfolded, the next small silica gel ball is extruded, when the injection amount of the dialysate in the abdominal cavity is enough, and extruding the large silica gel ball, enabling the large silica gel ball to flow along with the dialysate and be clamped at the abdominal cavity interface, rotating the three-way ball valve to close the infusion tube, pulling out the peritoneal dialysis infusion and exchange system, covering the large silica gel ball with an iodophor cover, and tightly connecting the large silica gel ball with the abdominal cavity interface. After the dialyzate is stored in the body for a specified time, the iodophor cap is taken down, the hole of the large silica gel ball is clamped by tweezers, the superfine fiber soft substance tows are taken out, then a new peritoneal dialysis liquid transferring and changing system is connected to the abdominal cavity interface, the three-way ball valve is rotated to connect the peritoneal dialysis tube with the waste liquid tube, the waste liquid bag is placed on the ground, the waste liquid is introduced into the waste liquid bag under the action of gravitational potential energy, the three-way interface is rotated after the drainage of the waste liquid is finished, the liquid transferring tube is connected with the peritoneal dialysis tube, and the dialyzate and the superfine fiber soft substance tows are injected into the abdominal cavity again.
According to the device for adsorbing uremia by the superfine fiber soft substance tows and the using method thereof, the superfine fiber surface contains the adsorption material capable of adsorbing urea such as zinc oxide and the like, so that substances such as urea and the like in the peritoneal dialysis solution can be continuously adsorbed, and the concentration of urea in the dialysis solution is reduced. The fibre bundle in the abdominal cavity has sufficient length, fibre bundle between the little silica gel ball can also scatter, these all increase the adsorption efficiency of silk bundle, thereby urea keeps lower concentration in the longer time in making the dislysate, make toxin in the blood pass the continuous mass transfer of vascular wall to the peritoneal cavity penetrant under the drive of osmotic pressure, and can prolong the live time of dislysate by a wide margin, thereby reach and reduce the dislysate and change the frequency, thereby improve the dislysate live time, reduce the peritoneal dialysis frequency, the beneficial effect of the cycle is passed through to the extension peritoneal cavity.
Drawings
FIG. 1 is a schematic view of a device for adsorbing uremia by using a superfine fiber soft substance tow.
FIG. 2 is a schematic diagram of a peritoneal dialysis fluid exchange system of the device for adsorbing uremia by the superfine fiber soft substance tows.
Fig. 3 is a schematic view of the superfine fiber soft substance tow of the device for adsorbing uremia of the invention.
Fig. 4 is a schematic view of a tow storage structure on a transfusion tube of the device for adsorbing uremia by using the superfine fiber soft substance tow.
FIG. 5 is a schematic view showing that substances such as uremia and the like are adsorbed by the superfine fiber soft substance tows in the abdominal cavity after the device for adsorbing uremia by the superfine fiber soft substance tows finishes infusion
In the figure: 1-peritoneal dialysis tube; 2-abdominal cavity interface; 3-iodophor cap; 4-superfine fiber soft substance tow; 4-1-a small silica gel ball at the front end; 4-2-middle small silica gel ball; 4-3-rear end small silica gel ball; 4-ultrafine fibers; 4-5-a support wire; 4-6-large silica gel ball; 5, abdominal cavity; 6-three-way ball valve; 7-tow storage structure; 8-dialysate bag; 9-a sealing plug; 10, a transfusion tube; 11-waste pipe; 12-waste liquid bag.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention.
The invention provides a device for adsorbing uremia by using superfine fiber soft substance tows, which is shown in figure 1 and mainly comprises a peritoneal dialysis fluid infusion and exchange system, an peritoneal dialysis tube 1, an abdominal cavity interface 2 and superfine fiber soft substance tows 4. The peritoneal dialysis liquid transferring system comprises a three-way ball valve 6, a tow storage structure 7, a dialysate bag 8, a sealing plug 9, a liquid conveying pipe 10, a waste liquid pipe 11 and a waste liquid bag 12, as shown in figure 2, the three-way ball valve 6 is positioned at the connection part of an abdominal cavity interface 2, the liquid conveying pipe 10 and the waste liquid pipe 11, the peritoneal dialysis pipe 1, the liquid conveying pipe 10 and the waste liquid pipe 11 are controlled to be communicated with each other, the tail end part of the liquid conveying pipe 10 comprises the tow storage structure 7 and is used for storing superfine fiber soft substance tows 4, the other end of the liquid conveying pipe 10 is connected with the dialysate bag 8, the bag mouth of the dialysate bag 8 is provided with the sealing plug 9, and the opening and closing of the bag mouth of the dialysate bag 8 are controlled. A waste liquid pipe 11 connected with the three-way ball valve 6, and the other end is connected with a waste liquid bag 12. The superfine fiber soft substance tow 4 consists of a front end small silica gel ball 4-1, a middle small silica gel ball 4-2, a rear end small silica gel ball 4-3, superfine fibers 4-4, support wires 4-5 and a large silica gel ball 4-6, and is shown in figure 3. The infusion tube 10 is provided with a tow storage structure 7, as shown in fig. 4, the section of the tow storage structure 7 is three quarters of a circle, a small silica gel ball 4-1 at the front end is positioned at one end of the tow storage structure 7 close to the three-way ball valve 6, a large silica gel ball 4-6 is positioned at the other end of the tow storage structure 7, and the whole superfine fiber soft substance tow 4 is clamped by the tow storage structure 7.
The invention provides a using method of a device for adsorbing uremia by superfine fiber soft substance tows, which comprises the steps of breaking a sealing plug 9 at an outlet of a dialysate bag 8, enabling dialysate to flow into a perfusion tube 10 from the dialysate bag 8, and rotating a three-way ball valve 6 to enable an peritoneal dialysis tube 1 to be communicated with the perfusion tube 10. And step two, when the dialysate in the perfusion tube 10 flows stably, the front end small silica gel balls 4-1 in the tow storage structure 7 are pressed into the perfusion tube 10, and when the front end small silica gel balls 4-1 flow along with the dialysate and drive the superfine fibers 4-4 and the support wires 4-5 to be completely unfolded in the dialysate, the middle end small silica gel balls 4-2 are sequentially pressed into the perfusion tube 10. And step three, when the abdominal liquid amount in the abdominal cavity 5 reaches a preset value, pressing the large silica gel ball 4-6 into the infusion tube 10, wherein the large silica gel ball 4-6 flows along with the dialysate, and when the large silica gel ball 4-6 is clamped at the abdominal cavity interface 2, rotating the three-way ball valve 6 to close the infusion tube 10. And step four, pulling out the peritoneal dialysis fluid infusion and exchange system, covering the large silica gel balls 4-6 with the iodophor cap 3, and adsorbing substances such as urea and the like in the abdominal cavity 5 by the superfine fiber soft substance tows 4 at the moment, wherein the adsorption process can be kept for a long time, which is shown in figure 5. Step five, when the dialysis liquid is stored in the body for a specified time and is subjected to peritoneal dialysis for the second time in advance, the iodophor cap 3 at the peritoneal interface 2 is taken down, the forceps are used for clamping the holes on the large silica gel balls 4-6, the superfine fiber soft substance tows 4 are taken out, and then a new peritoneal dialysis liquid transferring and changing system is connected to the peritoneal interface 2. Step six, rotating the three-way ball valve 6 to connect the peritoneal dialysis catheter 1 with the waste liquid tube 11, placing the waste liquid bag 12 on the ground, introducing the waste liquid into the waste liquid bag 12 under the action of gravitational potential energy, rotating the three-way ball valve 6 after the drainage of the waste liquid is finished to close the waste liquid tube 11, and repeating the steps from the first step to the fourth step.
Claims (8)
1. A device for adsorbing uremia by superfine fiber soft substance tows is characterized in that: the peritoneal dialysis transfusion system comprises a peritoneal dialysis transfusion system, an peritoneal dialysis tube, an abdominal cavity interface, an iodophor cap and superfine fiber soft substance tows, wherein the peritoneal dialysis transfusion system comprises a dialysate bag, a transfusion tube, a sealing plug, a waste liquid bag, a waste liquid tube and a three-way ball valve; the dialysate bag is well sealed, so that the dialysate is prevented from being polluted by the external environment, the sealing plug is positioned at the outlet of the dialysate bag, the dialysate bag is sealed, the sealing plug is broken, so that the dialysate can flow into the liquid conveying pipe, the three-way ball valve is connected to the tail end of the liquid conveying pipe and is connected with the abdominal cavity interface and the waste liquid pipe, and the three-way ball valve controls the connection of the three pipelines; the tail end of the waste liquid pipe is connected with a waste liquid bag, an abdominal cavity joint connected with the three-way ball valve is made of titanium alloy materials, and the abdominal cavity joint has the advantages of high strength, corrosion resistance and no magnetism, one end outside the peritoneal dialysis tube body is connected with the abdominal cavity joint, the other end of the peritoneal dialysis tube body is placed in an abdominal cavity through a minimally invasive surgery, and the peritoneal dialysis tube is made of polymers with good biocompatibility; the end part of the transfusion tube is provided with a superfine fiber soft substance tow storage structure, the superfine fiber soft substance tow consists of superfine fibers, a plurality of small silica gel balls and a large silica gel ball, the large silica gel ball is positioned at one end of the superfine fiber soft substance tow, the plurality of small silica gel balls are positioned at the other end and the middle section of the superfine fiber soft substance tow, and the diameter of the large silica gel ball is slightly larger than the inner hole of the abdominal cavity joint; when the superfine fiber soft substance tows flow along with the peritoneal fluid, the large silica gel ball is clamped at the joint of the peritoneal cavity of the peritoneal fluid interface, and the small silica gel ball flows into the peritoneal cavity along with the peritoneal fluid; the iodophor cap is in threaded sealing connection with the abdominal cavity interface, and can completely cover the large silica gel ball to ensure sealing; the superfine fiber soft substance tow is prepared from a polymer with biological safety, and the surfaces of the superfine fiber soft substance tow fibers contain an adsorption material of metabolic waste such as urea.
2. The device for adsorbing uremia by using the superfine fiber soft substance tows as claimed in claim 1, is characterized in that: the end part of the transfusion tube is provided with a superfine fiber soft substance tow storage structure, the section of the superfine fiber soft substance tow storage structure is three quarters of a circle, and the superfine fiber soft substance tow can be clamped in the structure.
3. The device for adsorbing uremia by using the superfine fiber soft substance tows as claimed in claim 2, is characterized in that: the superfine fiber soft material filament bundle is prepared with the mixture of polymer with biological safety and zinc oxide and through differential melt electrostatic spinning process.
4. The device for adsorbing uremia by using the superfine fiber soft substance tows as claimed in claim 3, is characterized in that: the length of the superfine fiber soft substance tow is 1.5-3 times of the length of the peritoneal dialysis tube, and the middle section of the superfine fiber soft substance tow is restrained by a plurality of small silica gel balls which are uniformly distributed.
5. The device for adsorbing uremia by using the superfine fiber soft substance tows as claimed in claim 1, is characterized in that: the surface of the large silica gel ball is provided with holes.
6. The device for adsorbing uremia by using the superfine fiber soft substance tows as claimed in claim 4, wherein: the middle of the superfine fiber soft substance tow contains a supporting filament with the diameter of 100-300 microns, the supporting filament is made of the same material as the superfine fiber soft substance tow, and the supporting filament can be a filament or a yarn.
7. The device for adsorbing uremia by using the superfine fiber soft substance tows as claimed in claim 6, wherein: the supporting wire is made of a material which has biological safety and higher strength and is different from the superfine fiber soft substance wire bundle, and the diameter is determined according to the required borne tension.
8. The use method of the device for adsorbing uremia by the superfine fiber soft substance tows is characterized in that: the device for adsorbing uremia by using the superfine fiber soft substance tows as claimed in claim 6, wherein in the first step, a sealing plug at the outlet of the dialysate bag is broken, so that dialysate flows into a perfusion tube from the dialysate bag, and a three-way ball valve is rotated to enable an peritoneal dialysis tube to be communicated with the perfusion tube; step two, when the dialysate in the infusion tube flows stably, the front-end small silica gel ball in the tow storage structure is pressed into the infusion tube, and when the front-end small silica gel ball flows along with the dialysate and drives the superfine fibers and the supporting wires to be completely unfolded in the liquid flow, the middle-end small silica gel ball is sequentially pressed into the infusion tube; step three, when the amount of the peritoneal dialysis solution in the abdominal cavity reaches a preset value, pressing the large silica gel ball into the infusion tube, wherein the large silica gel ball flows along with the dialysis solution, and when the large silica gel ball is clamped at the interface of the abdominal cavity, rotating the three-way ball valve to close the infusion tube; step four, pulling out the peritoneal dialysis fluid infusion and exchange system, covering the large silica gel ball with an iodophor cap, and adsorbing substances such as urea and the like in the abdominal cavity by the superfine fiber soft substance tows; step five, when the dialysis liquid is stored in the body for a specified time and is subjected to peritoneal dialysis for the second time, taking down an iodophor cap at the interface of the peritoneal cavity, clamping the hole on the large silica gel ball by using forceps, taking out the superfine fiber soft substance tows, and then connecting a new peritoneal dialysis liquid exchange system to the interface of the peritoneal cavity; and step six, rotating the three-way ball valve to connect the peritoneal dialysis catheter with the waste liquid pipe, placing the waste liquid bag on the ground, introducing the waste liquid into the waste liquid bag under the action of gravitational potential energy, rotating the three-way ball valve after the drainage of the waste liquid is finished to close the waste liquid pipe, and repeating the step one to the step four.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202111486417.XA CN114042197B (en) | 2021-12-07 | 2021-12-07 | Device for absorbing urea toxins by superfine fiber soft material tows and application method thereof |
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| CN202111486417.XA CN114042197B (en) | 2021-12-07 | 2021-12-07 | Device for absorbing urea toxins by superfine fiber soft material tows and application method thereof |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1471936A (en) * | 1973-07-05 | 1977-04-27 | Sartorius Membranfilter Gmbh | Apparatus for an method of removing substances intended for excretion in the urine from blood |
| US20050029193A1 (en) * | 2000-03-24 | 2005-02-10 | Immunocept, L.L.C. | Hemofiltration systems, methods and devices for treatment of chronic and acute diseases |
| CN102202702A (en) * | 2008-11-03 | 2011-09-28 | 弗雷泽纽斯医疗保健控股有限公司 | Portable peritoneal dialysis system |
| CN202497521U (en) * | 2012-02-15 | 2012-10-24 | 四川大学华西医院 | A peritoneal dialysis system |
| US20210039016A1 (en) * | 2019-08-05 | 2021-02-11 | Fresenius Medical Care Holdings, Inc. | Cation exchange materials for dialysis systems |
-
2021
- 2021-12-07 CN CN202111486417.XA patent/CN114042197B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1471936A (en) * | 1973-07-05 | 1977-04-27 | Sartorius Membranfilter Gmbh | Apparatus for an method of removing substances intended for excretion in the urine from blood |
| US20050029193A1 (en) * | 2000-03-24 | 2005-02-10 | Immunocept, L.L.C. | Hemofiltration systems, methods and devices for treatment of chronic and acute diseases |
| CN102202702A (en) * | 2008-11-03 | 2011-09-28 | 弗雷泽纽斯医疗保健控股有限公司 | Portable peritoneal dialysis system |
| CN202497521U (en) * | 2012-02-15 | 2012-10-24 | 四川大学华西医院 | A peritoneal dialysis system |
| US20210039016A1 (en) * | 2019-08-05 | 2021-02-11 | Fresenius Medical Care Holdings, Inc. | Cation exchange materials for dialysis systems |
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