CN114033896B

CN114033896B - Device for monitoring hemodynamics by penetrating catheter through wall of low-pressure hypoxia chamber

Info

Publication number: CN114033896B
Application number: CN202210023903.6A
Authority: CN
Inventors: 姜海明; 杨丽华; 周红霞
Original assignee: Yantai Fengquan Biotechnology Co ltd
Current assignee: Yantai Fengquan Biotechnology Co ltd
Priority date: 2022-01-11
Filing date: 2022-01-11
Publication date: 2022-03-22
Anticipated expiration: 2042-01-11
Also published as: CN114033896A

Abstract

The invention discloses a device for a hemodynamic monitoring catheter to penetrate through a low-pressure and low-oxygen cabin wall, which relates to the technical field of pipe sealing and comprises a cabin body, a first placing mechanism, an anti-falling mechanism, a second placing mechanism, a clamping mechanism and an air leakage mechanism, wherein placing holes are formed in two sides of the cabin body, the first placing mechanism is installed in each placing hole, the second placing mechanism is installed in each first placing mechanism, the clamping mechanism is installed in each second placing mechanism, and a connecting pipe is installed in each clamping mechanism. This device that low pressure hypoxia chamber bulkhead was run through to hemodynamic monitoring pipe not only is convenient for the connecting pipe to run through at the in-process that uses, simultaneously connect the in-process of installation can effectually reduce the clearance between the connection part to improve the accuracy that detects data.

Description

Device for monitoring hemodynamics by penetrating catheter through wall of low-pressure hypoxia chamber

Technical Field

The invention relates to the technical field of pipe fitting sealing, in particular to a device for a hemodynamic monitoring catheter to penetrate through a low-pressure hypoxia chamber wall.

Background

Altitude is in the plateau environment above 3000 m, and hypoxia has great influence on human body. The disease caused by high altitude hypoxia is the key point of research of high altitude medicine and anti-hypoxia medicine, and the preparation of the experimental animal model of hypoxia is an important means for realizing scientific research in the field. In recent years, related researches on an animal model with low-pressure and low-oxygen damage are in a bottleneck stage, the animal model with low-pressure and low-oxygen damage is not stable enough, and more evaluation indexes are needed, wherein invasive hemodynamic monitoring on the animal model is one of difficulties, a pressure container of a low-pressure and low-oxygen chamber is a high-strength closed container with a larger volume, a central control system controls a vacuum pump to provide gas circulation power, and a low-pressure and low-oxygen environment in the low-pressure and low-oxygen chamber is maintained; air, nitrogen gas, oxygen valve are controlled, effective discontinuity or continuous taking a breath is carried out, guarantee the interior gaseous continuous circulation of hypoxemia cabin of low pressure, provide the experimental environment of simulation high altitude for the laboratory glassware.

The Chinese patent with publication number CN111981207A discloses a device for a hemodynamic monitoring catheter to penetrate through a low-pressure and low-oxygen cabin wall, which comprises a rubber plug, wherein the rubber plug comprises a cylindrical body, a middle hole is formed in the middle of the cylindrical body, cylindrical grooves are formed in two ends of the cylindrical body, and an arc-shaped notch is formed in the axial length direction of the cylindrical body from the middle hole to the outer surface of the cylindrical body; the device can realize that the rat hemodynamic monitoring catheter penetrates through the bulkhead of the low-pressure hypoxia chamber, invasive hemodynamic monitoring and arterial blood gas analysis are carried out under the closed environment of the low-pressure hypoxia chamber, and the sterile conditions of various experimental operations are ensured.

However, the existing devices still have some problems in the using process:

1. the rubber plug is made of a soft material, but when the pressure difference distance between the air inside and outside the cabin is large, the condition that the connection between the rubber plug and the cabin is loosened can be caused under the influence of the pressure difference, so that the pressure inside the cabin is influenced, and the detection data is inaccurate;

2. in the using process, as the size of the rubber plug is relatively fixed with the size of the corresponding hole formed in the cabin, when the size of the rubber plug is smaller than the size of the hole formed in the low oxygen cabin, the pressure difference between the inside and the outside of the low oxygen cabin can be influenced, so that the detection data is influenced, and if the size of the rubber plug is larger than or equal to the size of the hole formed in the low oxygen cabin, the rubber plug is difficult to install;

3. in the process of detecting, the material of connecting pipe is often adopted to the through pipe, and the connecting pipe is inserting the in-process in the cabin, and the phenomenon of bending can take place for probably the connecting pipe to the data that influence detected.

Disclosure of Invention

Embodiments of the present invention provide a device for a hemodynamic monitoring catheter to penetrate through a wall of a hypoxic chamber to solve the problems of the prior art.

The embodiment of the invention adopts the following technical scheme: the device for the hemodynamics monitoring catheter to penetrate through the bulkhead of the low-pressure and low-oxygen cabin comprises a cabin body and further comprises a first placing mechanism, an anti-falling mechanism, a second placing mechanism, a clamping mechanism and an air leakage mechanism, wherein placing holes are formed in two sides of the cabin body, the first placing mechanism is installed in the placing holes, the anti-falling mechanism is installed on the outer surface of the first placing mechanism, one end of the first placing mechanism is connected with the air leakage mechanism, the second placing mechanism is installed in the first placing mechanism, the clamping mechanism is installed in the second placing mechanism, a connecting pipe is installed in the clamping mechanism, the clamping mechanism comprises three adjusting plates, three clamping grooves, three clamping plates and three rotating plates, the three adjusting plates are installed outside the connecting pipe, each clamping groove is internally provided with a corresponding clamping groove, one end of each clamping groove is connected with one end of the corresponding clamping plate, every the other one end of grip block with correspond another grip groove one end is connected, and every links to each other through shrink spring coupling between the grip block, the external screw thread has been seted up to the regulating plate surface, and every the one end of regulating plate with correspond the rotor plate is connected.

Further, the second placing mechanism comprises an expansion inner shell and an internal thread, the expansion inner shell is installed on the outer side of the adjusting plate, the internal thread is formed in the inner surface of the expansion inner shell, and the expansion inner shell is in threaded connection with the adjusting plate.

Further, first mechanism of placing is including adding gas pocket, four standing grooves, inflation shell, first inner shell, closure plate, two bottom plates, four limiting plates and two holes of disappointing, first inner shell is installed at the surface of inflation inner shell, and installs the inflation shell outside the first inner shell, be connected with the closure plate between first inner shell and the inflation shell, and seted up two holes of disappointing in the closure plate, the bottom plate is passed through at the both ends of first inner shell and inflation shell and is connected, one of them the bottom plate is connected with the gas pocket jogged joint, four standing grooves have been seted up to inflation shell surface, and every the rotation hole has all been seted up in the standing groove, and the internal surface all is provided with the limiting plate in every standing groove.

Further, anti-disengaging mechanism includes cooperation board, two pivots, baffle and anticreep spring, the cooperation board is installed in the standing groove, set up the rotation hole in the standing groove, the pivot is installed to the both sides of cooperation board one end, and normal running fit between pivot and the rotation hole, one of them pivot surface mounting has the baffle, through the anticreep spring coupling between cooperation board and the expansion shell.

Further, mechanism loses heart includes two guide slots, connecting plate, installation shell, sprue, two guide blocks and coupling spring, the installation shell is installed in disappointing hole one end, and installs the connecting plate in the installation shell, and the one end of connecting plate is connected with coupling spring's one end, coupling spring's other one end is connected with the sprue, the guide block is installed to the both sides of sprue, two guide slots have been seted up to installation shell internal surface, every the guide slot all with correspond sliding connection between the guide block.

Further, three regulating plates are arranged on the outer surface of the connecting pipe in an annular equidistant mode, and the inner surfaces of the regulating plates are made of soft materials.

Furthermore, the expansion outer shell and the expansion inner shell are both made of soft rubber materials, and the hardness of the first inner shell is greater than that of the expansion outer shell and the expansion inner shell.

Further, the expansion inner shell is the back taper design, and the internal diameter of expansion inner shell is greater than the external diameter of connecting pipe.

Compared with the prior art, the invention has the beneficial effects that:

firstly, because the expansion inner shell and the expansion outer shell are made of plastic materials, when air is added through the air adding hole, the expansion inner shell can expand under the influence of air pressure so as to eliminate the gap generated after the connection of the expansion outer shell and the cabin body is completed, meanwhile, when the inner expansion shell can not be expanded and the internal air pressure reaches a certain degree, the blocking block can be flushed away by the air, thereby extruding the expansion inner shell, the expansion inner shell is extruded inwards under the influence of gas, thereby reducing the connection gap between the expansion inner shell and the adjusting plate, effectively avoiding the phenomenon of air exchange inside and outside the cabin body when low-pressure and low-oxygen experiments are carried out, increasing the accuracy of experimental data, and because the expansion outer shell is expanded firstly and the expansion inner shell is expanded secondly in the using process, due to different degrees of deformation inside and outside, the separated expansion can ensure the close contact between the expanded connector and the expanded connector;

secondly, in the using process, as the baffle is arranged on the outer surface of the expansion shell, when the expansion shell is tightly connected with the cabin body and the cabin body starts a low-pressure and low-oxygen experiment, when the air pressure inside and outside the cabin body is different, the expansion shell can be extruded under the influence of the pressure difference to generate displacement, and after the expansion shell is installed, the baffle can be popped out under the action of the anti-falling spring, so that the expansion shell is effectively prevented from falling under the influence of the air pressure;

its third, in-process connecting the connecting pipe, at first place the connecting pipe between the regulating plate, because be provided with the grip block with shrink spring coupling between the regulating plate, back in the regulating plate is installed to the connecting pipe, can contract between the grip block, thereby carry out preliminary location to the connecting pipe, install the inflation inner shell with the cooperation board through the rotor plate afterwards, in-process installing, along with constantly getting into of cooperation board because inflation inner shell internal diameter constantly diminishes, make the cooperation board constantly shrink, thereby reduce the clearance between cooperation board and the connecting pipe, avoid influencing the data of experiment owing to there being the clearance, effectively avoid appearing the connecting pipe simultaneously and carry out the in-process that runs through and appear folding phenomenon.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.

FIG. 1 is a schematic perspective view of the present invention;

FIG. 2 is a schematic side view of the present invention;

FIG. 3 is a schematic view of the external structure of the first placement mechanism of the present invention;

FIG. 4 is a schematic view of the internal structure of the first placement mechanism of the present invention;

FIG. 5 is an enlarged view of the structure at A in FIG. 4 according to the present invention;

FIG. 6 is a schematic view of the connecting structure of the air release mechanism of the present invention;

FIG. 7 is an enlarged view of the structure of FIG. 6B according to the present invention;

FIG. 8 is a schematic view of the internal structure of a second placement mechanism of the present invention;

fig. 9 is a schematic structural diagram of the clamping mechanism of the present invention.

Reference numerals:

1. a cabin body; 11. placing holes; 2. a first placement mechanism; 21. air holes are added; 22. a placement groove; 23. an expansion shell; 24. a first inner case; 25. a blocking plate; 26. a base plate; 27. a limiting plate; 28. an air release hole; 3. an anti-drop mechanism; 31. a mating plate; 32. a rotating shaft; 33. a baffle plate; 34. an anti-drop spring; 4. a second placement mechanism; 41. expanding the inner shell; 42. an internal thread; 5. a clamping mechanism; 51. an adjusting plate; 52. a clamping groove; 53. a clamping plate; 54. a rotating plate; 6. an air release mechanism; 61. a guide groove; 62. a connecting plate; 63. installing a shell; 64. blocking; 65. a guide block; 66. a spring is connected.

Detailed Description

The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are some, but not all embodiments of the present invention.

The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations. Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention.

All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.

As shown in fig. 1 to 9, an embodiment of the present invention provides a device for a hemodynamic monitoring catheter to penetrate through a low-pressure and low-oxygen cabin wall, comprising a cabin body 1, a first placing mechanism 2, an anti-dropping mechanism 3, a second placing mechanism 4, a clamping mechanism 5 and an air-releasing mechanism 6, wherein two sides of the cabin body 1 are provided with placing holes 11, the first placing mechanism 2 is installed in the placing holes 11, the anti-dropping mechanism 3 is installed on an outer surface of the first placing mechanism 2, one end of the first placing mechanism 2 is connected with the air-releasing mechanism 6, the second placing mechanism 4 is installed in the first placing mechanism 2, the clamping mechanism 5 is installed in the second placing mechanism 4, a connecting pipe is installed in the clamping mechanism 5, the clamping mechanism 5 comprises three adjusting plates 51, three clamping grooves 52, three clamping plates 53 and three rotating plates 54, the three adjusting plates 51 are installed outside the connecting pipe, and every all correspond in the regulating plate 51 and seted up centre gripping groove 52, every centre gripping groove 52 wherein one end all with correspond grip block 53 one end and be connected, every the other one end of grip block 53 with correspond another one the one end of grip block 52 is connected, and every links to each other through shrink spring coupling between the grip block 53, the external screw thread has been seted up to regulating plate 51 surface, and every the one end of regulating plate 51 with correspond rotating plate 54 connects.

Specifically, the second placing mechanism 4 includes an expansion inner shell 41 and an internal thread 42, the expansion inner shell 41 is installed on the outer side of the adjusting plate 51, the internal thread 42 is formed on the inner surface of the expansion inner shell 41, and the expansion inner shell 41 is in threaded connection with the adjusting plate 51.

In operation, this arrangement facilitates the connection between the inner inflatable shell 41 and the adjustment plate 51.

Specifically, first placing mechanism 2 includes air adding hole 21, four standing grooves 22, inflation shell 23, first inner shell 24, closure plate 25, two bottom plates 26, four limiting plates 27 and two holes 28 that lose heart, first inner shell 24 is installed at the surface of inflation inner shell 41, and first inner shell 24 installs inflation shell 23 outward, be connected with closure plate 25 between first inner shell 24 and the inflation shell 23, and set up two holes 28 that lose heart in the closure plate 25, the both ends of first inner shell 24 and inflation shell 23 are passed through bottom plate 26 and are connected, one of them bottom plate 26 is connected with air adding hole 21, four standing grooves 22, and every have been seted up to inflation shell 23 surface all seted up in the standing groove 22 and have rotated the hole, and the internal surface all is provided with limiting plate 27 in every standing groove 22.

Specifically, anti-disengaging mechanism 3 includes cooperation board 31, two pivot 32, baffle 33 and anti-disengaging spring 34, cooperation board 31 is installed in standing groove 22, the rotation hole has been seted up in standing groove 22, pivot 32 is installed to the both sides of cooperation board 31 one end, and normal running fit between pivot 32 and the rotation hole, one of them pivot 32 surface mounting has baffle 33, be connected through anti-disengaging spring 34 between cooperation board 31 and the expansion shell 23.

Specifically, mechanism 6 loses heart includes two guide ways 61, connecting plate 62, installation shell 63, sprue 64, two guide blocks 65 and coupling spring 66, installation shell 63 installs in disappointing hole 28 one end, and installs connecting plate 62 in the installation shell 63, and the one end of connecting plate 62 is connected with coupling spring 66's one end, coupling spring 66's other one end is connected with sprue 64, guide blocks 65 are installed to sprue 64's both sides, two guide ways 61, every have been seted up to installation shell 63 internal surface guide ways 61 all with correspond sliding connection between the guide blocks 65.

Specifically, the three adjusting plates 51 are arranged on the outer surface of the connecting pipe in an annular equidistant manner, and the inner surfaces of the adjusting plates 51 are made of soft materials.

During operation, the connection pipe is clamped and fixed better by the arrangement.

Specifically, the outer expansion shell 23 and the inner expansion shell 41 are both made of soft rubber, and the hardness of the first inner shell 24 is greater than the hardness of the outer expansion shell 23 and the hardness of the inner expansion shell 41.

Specifically, the inner expansion shell 41 is designed in an inverted cone shape, and the inner diameter of the inner expansion shell 41 is larger than the outer diameter of the connection pipe.

The working principle is as follows: firstly, the first placing mechanism 2 is placed in a placing hole 11 formed in a cabin body 1, when placing is carried out, the first placing mechanism 2 is pushed, so that a matching plate 31 arranged on an expansion outer shell 23 is acted by force and can rotate inwards and extrude inwards along a rotating shaft 32, the matching plate 31 arranged at one end of the expansion outer shell 23 is pushed into the cabin body 1, then the matching plate 31 is bounced off under the action of an anti-falling spring 34, the situation that the expansion outer shell 23 falls off accidentally in the using process is effectively avoided, because the expansion inner shell 41 is fixedly connected with a first inner shell 24, the expansion inner shell 41 cannot fall off under the influence of air pressure, then, an adjusting plate 51 is connected with a connecting pipe, the connecting pipe is placed between the adjusting plates 51 in the connecting process, because the adjusting plates 51 are connected through clamping plates 53, and two corresponding clamping plates 53 are connected through a contraction spring, when the connecting pipe is placed into the adjusting plate 51, the adjusting plate 51 can primarily fix the connecting pipe under the action of the contraction spring, deformation of the connecting pipe is prevented in the process of insertion, then the adjusting plate 51 is in threaded connection with the expansion inner shell 41 through the rotating plate 54, the adjusting plate 51 is continuously contracted due to the fact that the inner diameter of the expansion inner shell 41 is smaller and smaller in the process of threaded connection, the influence of a connection gap on detection data is reduced, the connecting pipe can also be fixed in position, after the connecting pipe is connected, the first placing mechanism 2 is aerated through the aerating hole 21, in the process of aerating, due to the fact that the hardness of the first inner shell 24 is larger than that of the expansion outer shell 23, when the air pressure between the first inner shell 24 and the expansion outer shell 23 reaches a certain pressure, the expansion outer shell 23 deforms under the action of the air pressure, make inflation shell 23 closely cooperate with placing hole 11 inner wall, reach the effect of cancellation clearance, when inflation shell 23 can't expand, can dash blockout 64 under the influence of atmospheric pressure to make atmospheric pressure can act on inflation inner shell 41, inflation inner shell 41 takes place deformation under the effect of atmospheric pressure, thereby reduces the clearance between the screw-thread fit, increases experimental data's accuracy.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. Device for the hemodynamic monitoring catheter to penetrate the wall of a hypoxic chamber under low pressure, comprising a chamber body (1) characterized in that: the anti-dropping device is characterized by further comprising a first placing mechanism (2), an anti-dropping mechanism (3), a second placing mechanism (4), a clamping mechanism (5) and an air leaking mechanism (6), wherein placing holes (11) are formed in two sides of the cabin body (1), the first placing mechanism (2) is installed in the placing holes (11), the anti-dropping mechanism (3) is installed on the outer surface of the first placing mechanism (2), one end of the first placing mechanism (2) is connected with the air leaking mechanism (6), the second placing mechanism (4) is installed in the first placing mechanism (2), the clamping mechanism (5) is installed in the second placing mechanism (4), a connecting pipe is installed in the clamping mechanism (5), the clamping mechanism (5) comprises three adjusting plates (51), three clamping grooves (52), three clamping plates (53) and three rotating plates (54), the three adjusting plates (51) are installed outside the connecting pipe, and every all correspond in regulating plate (51) and seted up centre gripping groove (52), every centre gripping groove (52) wherein one end all is connected with the one end that corresponds grip block (53), every other one end of grip block (53) with correspond another one the one end of grip block (52) is connected, and every links to each other through shrink spring coupling between grip block (53), the external screw thread has been seted up to regulating plate (51) surface, and every the one end of regulating plate (51) with correspond rotor plate (54) are connected, second placement mechanism (4) are including inflation inner shell (41), the outside at regulating plate (51) is installed to inflation inner shell (41), and internal thread (42) have been seted up to inflation inner shell (41) internal surface, inflation inner shell (41) are threaded connection with regulating plate (51), first placement mechanism (2) are including adding gas hole (21), Four placing grooves (22), an expansion outer shell (23), a first inner shell (24), a blocking plate (25), two bottom plates (26), four limiting plates (27) and two air leakage holes (28), wherein the first inner shell (24) is installed on the outer surface of the expansion inner shell (41), the expansion outer shell (23) is installed outside the first inner shell (24), the blocking plate (25) is connected between the first inner shell (24) and the expansion outer shell (23), two air leakage holes (28) are formed in the blocking plate (25), the two ends of the first inner shell (24) and the two ends of the expansion outer shell (23) are connected through the bottom plates (26), one of the bottom plates (26) is connected with the air filling hole (21), the outer surface of the expansion outer shell (23) is provided with the four placing grooves (22), each placing groove (22) is internally provided with a rotating hole, and the limiting plate (27) is arranged on the inner surface in each placing groove (22), mechanism (6) loses heart and includes two guide ways (61), connecting plate (62), installation shell (63), sprue (64), two guide blocks (65) and coupling spring (66), install in disappointing hole (28) one end installation shell (63), and install in installation shell (63) connecting plate (62), and the one end of connecting plate (62) is connected with the one end of coupling spring (66), the other one end and the sprue (64) of coupling spring (66) are connected, guide block (65) are installed to the both sides of sprue (64), two guide ways (61), every have been seted up to installation shell (63) internal surface guide ways (61) all with correspond sliding connection between guide block (65).

2. The device for hemodynamic monitoring of claim 1, wherein said conduit extends through a wall of a hypoxic chamber, wherein: anti-disengaging mechanism (3) are including cooperation board (31), two pivot (32), baffle (33) and anticreep spring (34), cooperation board (31) are installed in standing groove (22), it has the rotation hole to have seted up in standing groove (22), pivot (32) are installed to the both sides of cooperation board (31) one end, and pivot (32) and rotate between the hole normal running fit, one of them pivot (32) surface mounting has baffle (33), be connected through anticreep spring (34) between cooperation board (31) and expansion shell (23).

3. The device for hemodynamic monitoring of claim 1, wherein said conduit extends through a wall of a hypoxic chamber, wherein: the three adjusting plates (51) are arranged on the outer surface of the connecting pipe in an annular and equidistant mode, and the inner surfaces of the adjusting plates (51) are made of soft materials.

4. The device for hemodynamic monitoring of claim 1, wherein said conduit extends through a wall of a hypoxic chamber, wherein: the expansion outer shell (23) and the expansion inner shell (41) are both made of soft rubber materials, and the hardness of the first inner shell (24) is greater than that of the expansion outer shell (23) and that of the expansion inner shell (41).

5. The device for hemodynamic monitoring of claim 1, wherein said conduit extends through a wall of a hypoxic chamber, wherein: the expansion inner shell (41) is designed to be inverted cone-shaped, and the inner diameter of the expansion inner shell (41) is larger than the outer diameter of the connecting pipe.