CN114028718A - Magnetic transmission composite treatment device based on data analysis - Google Patents

Magnetic transmission composite treatment device based on data analysis Download PDF

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CN114028718A
CN114028718A CN202111479082.9A CN202111479082A CN114028718A CN 114028718 A CN114028718 A CN 114028718A CN 202111479082 A CN202111479082 A CN 202111479082A CN 114028718 A CN114028718 A CN 114028718A
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rate
analysis
absorption
electrode plate
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CN114028718B (en
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何祥永
石彧
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Hunan Wanzhuo Medical Devices Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/002Magnetotherapy in combination with another treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/004Magnetotherapy specially adapted for a specific therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/02Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents

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  • Heart & Thoracic Surgery (AREA)
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  • Magnetic Treatment Devices (AREA)

Abstract

The invention provides a magnetic transmission composite treatment device based on data analysis, which comprises an electrode plate and an analysis control module, wherein the electrode plate is connected with the analysis control module through a connecting wire, the analysis control module outputs changed current, the changed current generates a magnetic field in the electrode plate, medicines in the electrode plate are absorbed by a human body through contacted skin under the action of the magnetic field, the electrode plate monitors the absorption rate of the medicines, monitoring data are fed back to the analysis control module through the connecting wire, and the analysis control module adjusts the output current according to the monitoring data; because the absorption rates of different physiques to the drugs under the stimulation of the same magnetic field are different, the system adjusts the output current in real time according to the real-time absorption rate, so that different individuals can absorb the drugs at the proper absorption rate, and the effectiveness of the drugs is improved.

Description

Magnetic transmission composite treatment device based on data analysis
Technical Field
The present disclosure relates generally to the field of magnetic transmission control, and more particularly to a magnetic transmission composite treatment device based on data analysis.
Background
The drug plays a very important role in the process of treating diseases, and common drug introduction methods include oral administration, injection and the like, but the drug has bitter taste during oral administration and pain during injection, and in order to avoid the defects, a method of directly introducing the drug from the skin surface to subcutaneous tissues through an electrode plate is generated, and the drug introduction speed has a small influence on the drug effect.
Now, a plurality of complex treatment devices have been developed, and through extensive search and reference, the existing treatment devices are found to be the devices disclosed in the publication numbers KR100816554B1, KR101493374B1, CN104524688B and KR101841111B1, comprising a substrate; an electrode disposed on the substrate; an adhesive sheet disposed on the substrate and having an opening in which the electrode is exposed; and a drug reservoir containing a local anesthetic and disposed in the opening of the adhesive sheet while being in contact with the electrode, the inner circumferential surface of the opening of the adhesive sheet and the outer circumferential surface of the drug reservoir being prevented from being in contact with human skin while being in contact with each other, and thereby reducing skin irritation. However, the electrode plate used in the device can only work in a fixed mode, and the working parameters can not be adjusted according to the constitutions of different individuals, so that the absorption rate of the medicine has larger deviation under different individuals, and the medicine effect of the medicine can not reach an ideal state.
Disclosure of Invention
The invention aims to provide a magnetic transmission composite treatment device based on data analysis aiming at the existing defects,
the invention adopts the following technical scheme:
a magnetic permeability composite treatment device based on data analysis comprises an electrode plate and an analysis control module, wherein the electrode plate generates a magnetic field and promotes the absorption of a medicine under the action of current, and the analysis control module analyzes the absorption rate of the medicine and provides the changed current for the electrode plate;
the electrode plate comprises a substrate, an electrode, a medicine storage bag and a monitoring piece, wherein an annular coil is arranged in the substrate, two ends of the annular coil are connected with the electrode and generate a magnetic field when the electrode is electrified, a variable closed space is formed between the substrate and the medicine storage bag, and the monitoring piece is used for detecting an air pressure value in the closed space;
the analysis control module comprises a current control unit, an air pressure analysis unit and an absorption analysis unit, the air pressure analysis unit is used for receiving air pressure data detected by the monitoring sheet and calculating the absorption rate of the medicine according to the air pressure data, the absorption analysis unit obtains current parameters according to the absorption rate analysis, and the current control unit outputs sawtooth wave current to the electrodes according to the current parameters;
absorption rate v of drugSuction deviceThe calculation formula is as follows:
Figure BDA0003394748430000021
wherein, P0Is the initial air pressure value, V, in the enclosed space0Is the initial volume value in the closed space, Δ t is the detection interval time, n is the interval number, and P (t) is the relation function of the detected air pressure value and the time;
the absorption analysis unit is divided into a lifting stage and a stabilizing stage when outputting current parameters, wherein the output current parameters comprise a lifting ratio Q _ out, a current increase rate Vup _ out and a current decrease rate Vdown _ out;
in the lifting stage, the parameter output formula is as follows:
Figure BDA0003394748430000022
Figure BDA0003394748430000023
Figure BDA0003394748430000024
wherein Vup _ now, Vdown _ now and Q _ now are the current increase rate, current decrease rate and lift ratio, vmax is the maximum suitable absorption rate of the drug, and vmin is the minimum suitable absorption rate of the drug;
in the stable stage, the parameter output formula is as follows:
Figure BDA0003394748430000025
Figure BDA0003394748430000026
Figure BDA0003394748430000027
in the lifting stage, the output current can enable the drug absorption rate to rapidly reach a [ vmin, vmax ] interval, and in the stabilizing stage, the output current can enable the drug absorption rate to be stabilized in the [ vmin, vmax ] interval;
further, the sawtooth waveform current parameter includes a period T, a minimum current value IminMaximum current value ImaxStep-up-down ratio Q, current increase rate VupAnd current reduction rate VdownWherein the current increase rate VupAnd current reduction rate VdownThe four parameters are calculated to obtain:
Figure BDA0003394748430000031
Figure BDA0003394748430000032
the current control unit adjusts the period T and the lowest current value IminMaximum current value ImaxAnd a step-up/step-down ratio Q to increase the current increase rate VupAnd current reduction rate VdownMeeting the parameter requirements of the absorption analysis unit;
furthermore, the electrode plate is connected with the analysis control module through a connecting line, the connecting line comprises an electrode line and a data line, the electrode line is connected with an electrode in the electrode plate, and the data line is connected with a detection sheet in the electrode plate;
further, when the current control unit adjusts the period T, in a boost phase, the adjustment range of the period T is in a small value interval, and in a stabilization phase, the adjustment range of the period T is in a large value interval;
furthermore, the electrode plate also comprises a warm ring, the warm ring is connected with the annular coil in the substrate through a heat conducting wire, and when the annular coil is electrified, the generated heat can improve the temperature of the warm ring and promote subcutaneous vasodilatation.
The beneficial effects obtained by the invention are as follows:
this system produces the alternating magnetic field of direction through the electric current of output zigzag, the increase rate and the decrement of electric current influence the power in magnetic field, the lift ratio of electric current influences the direction rate of change in magnetic field, and the power and the direction rate of change in magnetic field produce the influence to the absorption of skin to the medicine again, this system is through gathering the analysis to medicine absorption data, the electric current of output real-time change, make medicine absorption rate can be quick reach and stabilize in suitable interval, to the individual homoenergetic messenger's medicine effect of difference reach ideal state.
For a better understanding of the features and technical content of the present invention, reference should be made to the following detailed description of the invention and accompanying drawings, which are provided for purposes of illustration and description only and are not intended to limit the invention.
Drawings
FIG. 1 is a schematic view of the overall structural framework of the present invention;
FIG. 2 is a schematic view of the electrode sheet of the present invention;
FIG. 3 is a schematic diagram of the analysis control module according to the present invention;
FIG. 4 is a schematic diagram of the output current waveform and various parameters of the present invention;
FIG. 5 is a graph showing the effect of the drug absorption rate of the present invention at various stages;
fig. 6 is a schematic view of an overall sample of the product of the present invention.
Detailed Description
The following is a description of embodiments of the present invention with reference to specific embodiments, and those skilled in the art will understand the advantages and effects of the present invention from the disclosure of the present specification. The invention is capable of other and different embodiments and its several details are capable of modification in various other respects, all without departing from the spirit and scope of the present invention. The drawings of the present invention are for illustrative purposes only and are not intended to be drawn to scale. The following embodiments will further explain the related art of the present invention in detail, but the disclosure is not intended to limit the scope of the present invention.
The first embodiment.
The embodiment provides a magnetic permeable composite treatment device based on data analysis, which is combined with a graph 1 and comprises an electrode plate and an analysis control module, wherein the electrode plate generates a magnetic field and promotes the absorption of a medicine under the action of current, and the analysis control module analyzes the absorption rate of the medicine and provides the medicine to the electrode plate so as to generate variable current;
the electrode plate comprises a substrate, an electrode, a medicine storage bag and a monitoring piece, wherein an annular coil is arranged in the substrate, two ends of the annular coil are connected with the electrode and generate a magnetic field when the electrode is electrified, a variable closed space is formed between the substrate and the medicine storage bag, and the monitoring piece is used for detecting an air pressure value in the closed space;
the analysis control module comprises a current control unit, an air pressure analysis unit and an absorption analysis unit, the air pressure analysis unit is used for receiving air pressure data detected by the monitoring sheet and calculating the absorption rate of the medicine according to the air pressure data, the absorption analysis unit obtains current parameters according to the absorption rate analysis, and the current control unit outputs sawtooth wave current to the electrodes according to the current parameters;
absorption rate v of drugSuction deviceThe calculation formula is as follows:
Figure BDA0003394748430000041
wherein, P0Is the initial air pressure value, V, in the enclosed space0Is the initial volume value in the closed space, Δ t is the detection interval time, n is the interval number, and P (t) is the relation function of the detected air pressure value and the time;
the absorption analysis unit is divided into a lifting stage and a stabilizing stage when outputting current parameters, wherein the output current parameters comprise a lifting ratio Q _ out, a current increase rate Vup _ out and a current decrease rate Vdown _ out;
in the lifting stage, the parameter output formula is as follows:
Figure BDA0003394748430000051
Figure BDA0003394748430000052
Figure BDA0003394748430000053
wherein Vup _ now, Vdown _ now and Q _ now are the current increase rate, current decrease rate and lift ratio, vmax is the maximum suitable absorption rate of the drug, and vmin is the minimum suitable absorption rate of the drug;
in the stable stage, the parameter output formula is as follows:
Figure BDA0003394748430000054
Figure BDA0003394748430000055
Figure BDA0003394748430000056
in the lifting stage, the output current can enable the drug absorption rate to rapidly reach a [ vmin, vmax ] interval, and in the stabilizing stage, the output current can enable the drug absorption rate to be stabilized in the [ vmin, vmax ] interval;
the sawtooth waveform current parameter comprises a period T and a minimum current value IminMaximum current value ImaxStep-up-down ratio Q, current increase rate VupAnd current reduction rate VdownWherein the current increase rate VupAnd current reduction rate VdownThe four parameters are calculated to obtain:
Figure BDA0003394748430000057
Figure BDA0003394748430000058
the current control unit adjusts the period T and the lowest current value IminMaximum current value ImaxAnd a step-up/step-down ratio Q to increase the current increase rate VupAnd current reduction rate VdownMeeting the parameter requirements of the absorption analysis unit;
the electrode plate is connected with the analysis control module through a connecting wire, the connecting wire comprises an electrode wire and a data wire, the electrode wire is connected with an electrode in the electrode plate, and the data wire is connected with a detection sheet in the electrode plate;
when the current control unit adjusts the period T, the adjusting range of the period T is in a small value interval in a lifting stage, and the adjusting range of the period T is in a large value interval in a stabilizing stage;
the electrode plate further comprises a warm ring, the warm ring is connected with the annular coil in the substrate through the heat conducting wire, and when the annular coil is electrified, the temperature of the warm ring can be increased through generated heat, so that subcutaneous vasodilatation is promoted.
Example two.
The embodiment includes the whole content in the first embodiment, and provides a magnetic permeability composite treatment device based on data analysis, which comprises an electrode plate and an analysis control module, wherein the electrode plate is connected with the analysis control module through a connecting wire, the analysis control module outputs a changed current, the changed current generates a magnetic field in the electrode plate, a medicine in the electrode plate is absorbed by a human body through contacted skin under the action of the magnetic field, the electrode plate monitors the absorption rate of the medicine, monitoring data are fed back to the analysis control module through the connecting wire, and the analysis control module adjusts the output current according to the monitoring data;
with reference to fig. 2, the electrode plate includes a substrate, an adhesive ring, an electrode, a drug storage bag, and a monitoring plate, wherein an annular coil is disposed in the substrate, two ends of the annular coil are connected to the electrode, the drug storage bag and the adhesive ring are disposed below the substrate, the adhesive ring is disposed outside the drug storage bag, the adhesive ring is used for adhering to the surface of skin, the monitoring plate is disposed between the substrate and the drug storage bag, a closed space is formed between the substrate and the drug storage bag, the size of the closed space is increased along with dialysis of the drug, and the monitoring plate is used for detecting air pressure change data in the closed space;
the connecting wire is internally provided with an electrode wire and a data wire, the electrode wire is connected with an electrode in the electrode plate, and the data wire is connected with a detection sheet in the electrode plate;
with reference to fig. 3, the analysis and control module includes a current control unit, an air pressure analysis unit and an absorption analysis unit, the air pressure analysis unit calculates an absorption rate of the drug according to the air pressure data detected by the detection sheet, the absorption analysis unit obtains a subsequent current output according to the absorption rate of the drug and a previous current output record analysis, and the current control unit controls an output current parameter according to the current output calculated by the absorption analysis unit;
the air pressure value detected by the monitoring piece is represented by a function P (t), and the absorption rate v calculated by the air pressure analysis unitSuction deviceComprises the following steps:
vsuction device=P0·V0·P-2(t)·P′(t);
Wherein, P0To closeInitial value of air pressure in space, V0For an initial volume value in the enclosed space, P' (t) is a derivative function of the function P (t);
since the function P (t) is generated from the detected data and cannot be written directly as an expression, the absorption rate vSuction deviceCan be written as:
Figure BDA0003394748430000071
wherein, Δ t is the detection interval time, and n is the interval number;
the higher the detection precision of the monitoring sheet is, the smaller the value of n is, and 1 is taken when n is minimum;
according to the drug attributes stored in the drug storage package, a suitable absorption rate interval [ vmin, vmax ] is preset in the analysis control module;
referring to fig. 4, the current outputted from the current control unit is a sawtooth waveform current, and the parameters thereof include a period T and a minimum current value IminMaximum current value ImaxStep-up-down ratio Q, current increase rate VupAnd current reduction rate VdownWherein, period T, lowest current value IminMaximum current value ImaxAnd the lifting ratio Q is directly controlled by the current control unit, and the current increase rate VupAnd current reduction rate VdownThe four parameters are calculated to obtain:
Figure BDA0003394748430000072
Figure BDA0003394748430000073
the magnetic field generated by the electrode plate comprises a forward magnetic field and a reverse magnetic field, sawtooth waveform current of one period T corresponds to the forward magnetic field and the reverse magnetic field, and the magnetic field intensity of the forward magnetic field and the magnetic field intensity of the reverse magnetic field are VupPositively correlated, the magnetic field strength of the reverse magnetic field and VdownPositive correlation, in the presence of a positive magnetic fieldThe ratio of time to the time when the reverse magnetic field exists is equal to the lifting ratio Q;
referring to fig. 5, the absorption analysis unit is divided into two stages when processing data, the first stage is a lifting stage in which the absorption rate of the drug can rapidly reach an appropriate absorption rate interval, and the second stage is a stabilizing stage in which the absorption rate of the drug does not exceed the range of the appropriate absorption rate interval;
the absorption analysis unit needs to use when processing data and the output current parameter is the current increase rate VupCurrent reduction rate VdownThe current data of the three parameters are represented by Vup _ now, Vdown _ now and Q _ now, and the output values are represented by Vup _ out, Vdown _ out and Q _ out;
in the lifting stage, the calculation formula of three output values is as follows:
Figure BDA0003394748430000081
Figure BDA0003394748430000082
Figure BDA0003394748430000083
in the stable stage, the calculation formula of three output values is as follows:
Figure BDA0003394748430000084
Figure BDA0003394748430000085
Figure BDA0003394748430000086
the absorption analysis unit outputs current parameters to the current control unit at fixed time intervals, and the current control unit compares the lifting ratio Q, the period T and the lowest current value IminAnd the highest current value ImaxAdjusting to make the current parameter meet the requirement;
in the lifting stage, the adjusting range of the period T is in a small value interval, so that the generated magnetic field changes rapidly, the stimulation to the skin can be improved, the absorption rate of the medicine is accelerated, in the stabilizing stage, the adjusting range of the period T is in a large value interval, so that the generated magnetic field changes slowly, the stimulation to the skin can be relieved, and the absorption rate of the medicine is stabilized;
the range of the small value interval is [0.1s, 0.5s ], and the range of the large value interval is [1s, 3s ];
the electrode plate also comprises a warm ring, the warm ring is arranged on the outer side of the adhesive ring and is connected with the annular coil in the substrate through a heat conducting wire, when current passes through the annular coil, the generated heat can be transferred into the warm ring along with the heat conducting wire, the warm ring is in contact with the skin, subcutaneous blood vessels can be expanded, the drug absorption rate is improved, and the warm ring is also provided with a radiating fin;
the lowest current value and the highest current value are set in a safe current range, the lowest current value and the highest current value are set in a larger area in the safe current range in a lifting stage, the temperature of the heating ring can be quickly lifted, and the lowest current value and the highest current value are set in a smaller area in the safe current range in a stabilizing stage, so that the heating ring is kept at a proper temperature.
The disclosure is only a preferred embodiment of the invention, and is not intended to limit the scope of the invention, so that all equivalent technical changes made by using the contents of the specification and the drawings are included in the scope of the invention, and further, the elements thereof can be updated as the technology develops.

Claims (5)

1. A magnetic transmission composite treatment device based on data analysis is characterized by comprising an electrode plate and an analysis control module, wherein the electrode plate generates a magnetic field and promotes the absorption of a medicine under the action of current, and the analysis control module analyzes the absorption rate of the medicine and provides the medicine to the electrode plate to generate variable current;
the electrode plate comprises a substrate, an electrode, a medicine storage bag and a monitoring piece, wherein an annular coil is arranged in the substrate, two ends of the annular coil are connected with the electrode and generate a magnetic field when the electrode is electrified, a variable closed space is formed between the substrate and the medicine storage bag, and the monitoring piece is used for detecting an air pressure value in the closed space;
the analysis control module comprises a current control unit, an air pressure analysis unit and an absorption analysis unit, the air pressure analysis unit is used for receiving air pressure data detected by the monitoring sheet and calculating the absorption rate of the medicine according to the air pressure data, the absorption analysis unit obtains current parameters according to the absorption rate analysis, and the current control unit outputs sawtooth wave current to the electrodes according to the current parameters;
absorption rate v of drugSuction deviceThe calculation formula is as follows:
Figure FDA0003394748420000011
wherein, P0Is the initial air pressure value, V, in the enclosed space0Is the initial volume value in the closed space, Δ t is the detection interval time, n is the interval number, and P (t) is the relation function of the detected air pressure value and the time;
the absorption analysis unit is divided into a lifting stage and a stabilizing stage when outputting current parameters, wherein the output current parameters comprise a lifting ratio Q _ out, a current increase rate Vup _ out and a current decrease rate Vdown _ out;
in the lifting stage, the parameter output formula is as follows:
Figure FDA0003394748420000012
Figure FDA0003394748420000013
Figure FDA0003394748420000014
wherein Vup _ now, Vdown _ now and Q _ now are the current increase rate, current decrease rate and lift ratio, vmax is the maximum suitable absorption rate of the drug, and vmin is the minimum suitable absorption rate of the drug;
in the stable stage, the parameter output formula is as follows:
Figure FDA0003394748420000015
Figure FDA0003394748420000016
Figure FDA0003394748420000021
in the lifting stage, the output current can enable the drug absorption rate to rapidly reach a [ vmin, vmax ] interval, and in the stabilizing stage, the output current can enable the drug absorption rate to be stabilized in the [ vmin, vmax ] interval.
2. The magnetic permeability complex treatment apparatus based on data analysis of claim 1, wherein the sawtooth waveform current parameters include period T, minimum current value IminMaximum current value ImaxStep-up-down ratio Q, current increase rate VupAnd current reduction rate VdownWherein, in the step (A),rate of current increase VupAnd current reduction rate VdownThe four parameters are calculated to obtain:
Figure FDA0003394748420000022
Figure FDA0003394748420000023
the current control unit adjusts the period T and the lowest current value IminMaximum current value ImaxAnd a step-up/step-down ratio Q to increase the current increase rate VupAnd current reduction rate VdownThe parameter requirements of the absorption analysis unit are met.
3. The magnetic transmission composite treatment device based on data analysis as claimed in claim 2, wherein the electrode plates and the analysis control module are connected through connecting wires, the connecting wires comprise electrode wires and data wires, the electrode wires are connected with the electrodes in the electrode plates, and the data wires are connected with the detection sheets in the electrode plates.
4. A magnetic transmission composite treatment device based on data analysis as claimed in claim 3, wherein the current control unit adjusts the period T in a lifting phase, wherein the adjustment range of the period T is in a small value interval, and in a stabilizing phase, the adjustment range of the period T is in a large value interval.
5. The composite magnetic transmission therapeutic device based on data analysis of claim 4, wherein the electrode plate further comprises a warm ring connected with the loop coil in the substrate through a heat conducting wire, and when the loop coil is electrified, the generated heat can increase the temperature of the warm ring to promote the expansion of subcutaneous blood vessels.
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2131794A1 (en) * 1992-03-13 1993-09-16 Joseph Gross Drug delivery devices
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