CN114026645A - 会聚抗体特异性序列模式的鉴定 - Google Patents

会聚抗体特异性序列模式的鉴定 Download PDF

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CN114026645A
CN114026645A CN202080028478.9A CN202080028478A CN114026645A CN 114026645 A CN114026645 A CN 114026645A CN 202080028478 A CN202080028478 A CN 202080028478A CN 114026645 A CN114026645 A CN 114026645A
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protein
amino acid
antigen
peptide
cell
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S·弗利单森
S·雷迪
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Olo Therapy Co ltd
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Eidgenoessische Technische Hochschule Zurich ETHZ
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    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
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    • G06N3/044—Recurrent networks, e.g. Hopfield networks
    • G06N3/0442—Recurrent networks, e.g. Hopfield networks characterised by memory or gating, e.g. long short-term memory [LSTM] or gated recurrent units [GRU]
    • G—PHYSICS
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    • G06N3/0455—Auto-encoder networks; Encoder-decoder networks
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    • G06N3/00—Computing arrangements based on biological models
    • G06N3/02—Neural networks
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    • G06N3/047—Probabilistic or stochastic networks
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
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    • G06N3/02—Neural networks
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    • G06N3/08—Learning methods
    • G06N3/0895—Weakly supervised learning, e.g. semi-supervised or self-supervised learning
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00—Computing arrangements based on biological models
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    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
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    • G06N7/00—Computing arrangements based on specific mathematical models
    • G06N7/01—Probabilistic graphical models, e.g. probabilistic networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/30—Detection of binding sites or motifs
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/30—Unsupervised data analysis

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CN202080028478.9A 2019-05-03 2020-05-02 会聚抗体特异性序列模式的鉴定 Pending CN114026645A (zh)

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US201962843010P 2019-05-03 2019-05-03
US62/843,010 2019-05-03
PCT/IB2020/054171 WO2020225693A1 (en) 2019-05-03 2020-05-02 Identification of convergent antibody specificity sequence patterns

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EP (1) EP3963590A1 (https=)
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Cited By (1)

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CN116895350A (zh) * 2023-08-04 2023-10-17 辽宁工业大学 一种在复合位移加载下波纹管的多轴疲劳寿命预测方法

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JP7648099B2 (ja) 2019-05-19 2025-03-18 ジャスト－エヴォテック バイオロジクス，インコーポレイテッド 機械学習法によるタンパク質配列の生成
CA3160429A1 (en) * 2019-12-06 2021-06-10 Philip M. KIM System and method for generating a protein sequence
US11388356B1 (en) * 2021-04-12 2022-07-12 Tetramem Inc. AI fusion pixel sensor using memristors
CN113393900B (zh) * 2021-06-09 2022-08-02 吉林大学 基于改进Transformer模型的RNA状态推断研究方法
US20250191674A1 (en) * 2022-02-28 2025-06-12 Genentech, Inc. Protein design with segment preservation
US12587274B2 (en) 2023-03-28 2026-03-24 Quantum Generative Materials Llc Satellite optimization management system based on natural language input and artificial intelligence
WO2025074981A1 (ja) * 2023-10-04 2025-04-10 国立大学法人大阪大学 抗体選別方法、コンピュータプログラム及び情報処理装置
US12368503B2 (en) 2023-12-27 2025-07-22 Quantum Generative Materials Llc Intent-based satellite transmit management based on preexisting historical location and machine learning
US12603701B2 (en) 2023-12-27 2026-04-14 Quantum Generative Materials Llc Distributed satellite constellation management and control system

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CN116895350B (zh) * 2023-08-04 2024-01-16 辽宁工业大学 一种在复合位移加载下波纹管的多轴疲劳寿命预测方法

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AU2020269607B2 (en) 2025-12-11
JP2024167413A (ja) 2024-12-03
IL287237A (en) 2021-12-01
US20220164627A1 (en) 2022-05-26
EP3963590A1 (en) 2022-03-09
JP2022530941A (ja) 2022-07-05
WO2020225693A1 (en) 2020-11-12
JP7602484B2 (ja) 2024-12-18
CN120526845A (zh) 2025-08-22
AU2020269607A1 (en) 2021-10-28
CA3132181A1 (en) 2020-11-12

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