CN113975540B

CN113975540B - Injector head assembly, injector body and injector

Info

Publication number: CN113975540B
Application number: CN202111415876.9A
Authority: CN
Inventors: 张明
Original assignee: Beijing Qs Medical Technology Co ltd
Current assignee: Beijing Qs Medical Technology Co ltd
Priority date: 2021-11-25
Filing date: 2021-11-25
Publication date: 2023-12-26
Anticipated expiration: 2041-11-25
Also published as: CN113975540A

Abstract

The invention provides an injection head assembly, an injector body and an injector. The injector head assembly is configured to be insertable into the distal opening of the injector body and rotatable to a locked position relative to the injector body and to compress the resilient member when the injector head assembly is inserted into the distal opening, wherein the end cap compresses the resilient member when the injector head assembly is in the locked position such that the resilient member springs back to block the injector head body in a rotational direction when the injector head assembly is in the locked position and the end cap is removed. The invention enables the injector head body to be prevented from rotating relative to the injector body towards the unlocked position with the injector head body and injector body properly locked in engagement and the end cap removed. To remove the injector head body, the end cap must be reinstalled and the injector head assembly removed in its entirety. Such an arrangement can avoid losing parts of the injector head assembly and make the operation more hygienic.

Description

Injector head assembly, injector body and injector

Technical Field

The present invention relates to medical devices for injecting liquid drugs. More particularly, the present invention relates to a syringe head assembly, a syringe body and a syringe. The syringe of the present invention may be a needleless syringe or a needleless syringe.

Background

There is a syringe in which, when the syringe head assembly is mounted to the syringe body and the cap is removed, the syringe head body may be rotated in the unloading direction to be independently removed from the syringe body. Such an operation may result in loss of the end cap. And the unloading operation may create some hygienic problems because the end cap does not cover the injector head body.

Accordingly, there is a need to provide a syringe body and syringe that at least partially address the above-described problems.

Disclosure of Invention

In order to overcome the above drawbacks, according to the present invention, there is provided a syringe head assembly, a syringe body and a syringe for a syringe. The engagement structure between the end cap and the syringe body of the injector head assembly of the present invention is constrained so that they remain continuously engaged before being properly mounted in a locked position relative to the syringe body, avoiding removal of the end cap with the syringe body virtually attached to the distal end of the syringe body, and improving the safety factor of operation.

In addition, the invention provides that the injector head body cannot be rotated relative to the injector body toward the unlocked position with the injector head body and the injector body properly locked in engagement and the end cap removed. To remove the injector head body, the end cap must be reinstalled and the injector head assembly removed in its entirety. Such an arrangement can avoid losing parts of the injector head assembly and make the operation more hygienic.

The invention is also more reasonable in that the engagement between the piston rod member and the injector body, can allow the engagement between the piston rod member and the injector body to be used to unlock the engagement between the piston rod member and the injector body without manual manipulation by the user.

The syringe body of the present invention provides a visual window for a user to view the contents of the drug storage vial and allows relative axial movement between the outer housing and the inner ram while preventing relative rotation. These arrangements can improve the accuracy and convenience of operation.

According to one aspect of the present invention, there is provided a syringe assembly having a syringe body with a distal opening and a resilient member disposed on and slightly protruding from a distal face of the syringe body, wherein the syringe assembly comprises:

the injection head comprises an injection head main body, wherein a cavity with an open proximal end is arranged in the injection head main body, and a micropore which is communicated with the cavity and the outside is arranged at the distal end of the injection head main body;

an end cap mounted to a distal end of the injector head body,

wherein the injector head assembly is configured to be insertable into a distal opening of the injector body and rotatable to a locked position relative to the injector body and to compress the resilient member when the injector head assembly is inserted into the distal opening, wherein the end cap compresses the resilient member when the injector head assembly is in the locked position such that the resilient member springs back to block the injector head body in a rotational direction when the end cap is removed.

In one embodiment, the end cap and the injector head body together define a circumferential ledge projecting radially outwardly and circumferentially continuous, the proximal face of the circumferential ledge being planar and capable of compression against the resilient member.

In one embodiment, the end cap defines at least two first boss portions, the injector head body defines at least two second boss portions, the at least two first boss portions and the at least two second boss portions together form the circumferential boss, and the first boss portions and the second boss portions are alternately arranged in the circumferential direction.

In one embodiment, the end cap includes an arm extending proximally from a body of the end cap, a proximal end of the arm constituting the first boss portion; the injection head main body is provided with a flange intermittently extending in the circumferential direction constituting the second boss portion.

In one embodiment, the arm is provided with a first projection on the inside of the proximal end, and the discontinuity of the flange constitutes a first mating feature, the distal end of which is provided with a small step,

wherein the small step is blocked distal to the first protrusion when the end cap and the syringe body are engaged; the first projection passes over the small step during disengagement of the end cap and the injector head body.

In one embodiment, the arms are deformable radially outwardly to enable the first projection to clear the small step.

According to another aspect of the present invention there is provided a syringe body for use with a syringe head assembly, the syringe head assembly comprising an axially separable syringe head body and an end cap,

wherein the syringe body has a distal opening and allows the injection head assembly to be inserted into the distal opening and then rotated to a locked position relative to the syringe body,

and, a distal end face of the syringe body is provided with a resilient member slightly protruding from the distal end face, the resilient member being configured to be compressible by the syringe head assembly upon insertion of the syringe head assembly into the distal end opening, and the resilient member being compressed by the end cap when the syringe head assembly is in the locked position; the resilient member springs back to block the injector head body in a rotational direction when the end cap is removed.

In one embodiment, the elastic member is configured as an elastic column extending in an axial direction, and the distal end face of the syringe body is provided with an elastic column groove for accommodating the elastic column and having an axial depth smaller than a length of the elastic column.

In one embodiment, the resilient member is compressed by a circumferential boss formed by a boss portion defined by the injector head body and a boss portion defined by the end cap, and the resilient member is positioned to: the elastic member is located at an uppermost stream end of a boss portion defined by the end cap in a mounting rotation direction when the injection head assembly is located at the lock position.

In one embodiment, the number of the elastic members is at least two, and at least two of the elastic members are uniformly arranged in the circumferential direction.

According to a further aspect of the present invention there is provided a syringe, wherein the syringe comprises:

a syringe body having a distal opening and having a resilient member located on a distal face of the syringe body that protrudes slightly from the distal face;

a syringe assembly comprising a syringe body and an end cap axially separable from and located on the syringe body, the syringe assembly being insertable into a distal opening of the syringe body and rotatable to a locked position relative to the syringe body,

wherein the resilient member is configured to be compressed by the injector head assembly when the injector head assembly is inserted into the distal opening and is compressed by the end cap when the injector head assembly is in the locked position; the resilient member springs back to block the injector head body in a rotational direction when the end cap is removed.

In one embodiment, the arms are deformable radially outwardly to enable the first projection to clear the small step,

and, an inner diameter at a distal opening of the syringe body is set to: when the injector head assembly is inserted into the distal opening of the injector body but not rotated to the locked position, the inner surface of the injector body and the outer surface of the arm contact; when the injector head assembly is in the locked position, a radial gap exists between the inner surface of the injector body and the outer surface of the arm, the radial gap providing room for radial deformation of the arm.

In one embodiment, the number of the elastic members is at least two, and the elastic members and the first boss portions are provided in one-to-one correspondence.

In one embodiment, the elastic member is located at an uppermost stream end of the first boss portion in the mounting rotation direction when the injection head assembly is located at the lock position.

Drawings

For a better understanding of the above and other objects, features, advantages and functions of the present invention, reference should be made to the preferred embodiments illustrated in the accompanying drawings. The same or similar reference numbers in the drawings refer to the same or similar parts. It will be appreciated by persons skilled in the art that the drawings are intended to schematically illustrate preferred embodiments of the invention, and that the scope of the invention is not limited in any way by the drawings, and that the various components are not drawn to scale.

FIG. 1 is a perspective view of a syringe according to a preferred embodiment of the present invention, with a portion of the structure at the proximal end of the syringe omitted;

FIG. 2 is an exploded view of the syringe of FIG. 1;

FIG. 3 is an exploded view of the injector head assembly of FIG. 2, but in an up-down direction in the drawing plane opposite to FIG. 2;

FIG. 4 is an assembled schematic view of the injector head assembly of FIG. 2 with the piston rod member engaged with the injector head body;

FIG. 5 is a schematic diagram of the cross-sectional view of FIG. 4;

FIG. 6 is an assembled schematic view of the injector head assembly of FIG. 2 with engagement between the piston rod member and the injector head body released;

fig. 7A-15B show perspective views of various stages in the use of the syringe shown in fig. 1.

Detailed Description

Hereinafter, the syringe body, and the injection head of the syringe according to the present invention will be described in detail with reference to the accompanying drawings. What follows is merely a preferred embodiment according to the present invention, and other ways of implementing the invention will occur to those skilled in the art on the basis of the preferred embodiment, and are within the scope of the invention.

The invention provides an injection head assembly of an injector and the injector. First, it should be noted that the directional terms and positional terms referred to in the present invention should be understood as relative directions and relative positions. Directional terms, positional terms referred to herein may be understood with reference to the drawings, for example, "axial," "axial direction," etc. referred to herein may be understood as directions along or parallel to the X-X direction in the drawings; reference herein to "radial", "radial direction", "circumferential direction", etc. are all directions about the X-X axis; reference to a "direction of rotation" in the present invention is to be understood as a direction of rotation about the X-X axis, which is substantially equivalent to a "circumferential direction". References herein to "proximal", "proximal direction", etc. are to directions along or parallel to the axis X-X that are closer to the operator (considering that the operator holds the syringe for aspiration and injection); the terms "distal", "distal direction", and the like in the present invention refer to a direction away from the operator in the direction along or parallel to the axis X-X, and also refer to a direction in which the liquid medicine is ejected in the injection step. The terms "proximal", "distal" and "distal" as used herein refer to the end cap, which is distal at one end and proximal at the end remote from the end cap.

Figures 1-15B illustrate a syringe and injector head assembly according to some preferred embodiments of the present invention. Although fig. 1-15B illustrate a needleless injector, needleless injector head assembly, it is to be understood that the present invention can be applied to needleless injectors, needleless injector head assemblies. The present invention enables accurate determination of the injection dose by introducing the liquid to be injected into a chamber (i.e., a drug sucking step to be described later) in the body of the injection head in advance, and such an injector and injection head assembly can be used in both a needleless injection manner and a needleless injection manner. Further, the injector and the injection head assembly can also realize the switching of the injection modes with and without needles. For example, the injection mode of the injector can be switched from needleless injection to needleless injection by attaching an injection needle to an injection micropore of the injection head. And the end cap may be provided to have a long size to enclose a portion of the injector head body and the needle attached to the front end of the injector head body, corresponding to the needle-containing injector head assembly, without the end cap interfering with the needle.

Referring to fig. 1 and 2, the syringe 1 includes a syringe body 100 and a syringe head assembly 200. The syringe body 100 in turn includes an outer housing 110 and an inner push rod 120 positioned within the outer housing 110 and axially movable relative to the outer housing 110. The syringe head assembly 200 can be mounted at the distal end of the syringe body 100. Figures 3-6 illustrate some detailed preferred arrangements of the injector head assembly 200 of figures 1-2.

Referring to fig. 3, the syringe assembly 200 includes a syringe body 210, a plunger rod member 220 attached to the proximal side of the syringe body 210, and an end cap 230 attached to the distal side of the syringe body 210. The injector body 210 is provided with a cavity 210c with an open proximal end, and the distal end of the injector body 210 is provided with micropores communicating the cavity 210c with the outside. The piston rod member 220 has a distally extending piston rod 220a, the piston rod 220a being distally located from the piston rod 220b. The piston rod member 220 is arranged proximally of the injector head body 210 and enables the piston rod 220a to extend into the cavity 210c.

The syringe body 210 and the end cap 230, and the syringe body 210 and the piston rod member 220 are all detachably engaged. And, during the process of mounting the syringe head assembly 200 to the syringe body 100: preventing axial separation of end cap 230 and injector head body 210 until the locked position is reached; preventing axial relative displacement of the injector body 210 and the injector body 100 in the locked position and allowing axial separation of the end cap 230 and the injector body 210.

In the present embodiment, in the process of mounting the syringe head assembly 200 to the syringe body 100, the syringe head assembly 200 is first inserted into the distal end of the syringe body 100 in the proximal direction (the position of the syringe head assembly 200 with respect to the syringe body 100 at this time is referred to as a first transition position), and then the syringe head assembly 200 is rotated in a rotation direction (which is referred to as a mounting rotation direction R1) to a locking position of the syringe head body 210 of the syringe head assembly 200 with respect to the syringe body 100; when it is desired to unload the injector head assembly 200 from the injector body 100, the injector head assembly 200 is first rotated in another rotational direction (referred to as the unloading rotational direction R2) opposite the installation rotational direction R1 to a first transitional position, and then the injector head assembly 200 is moved in a distal direction to be separated from the injector body 100.

Preferably, a limiting structure is correspondingly disposed in the syringe body 100 to axially limit the syringe head assembly 200 in the first transition position. That is, when the injector head assembly 200 is in the first transitional position, it cannot continue to move proximally relative to the injector body 100, but allows the injector head assembly 200 as a whole to move distally relative to the injector body 100.

Wherein the injector head body 210 is locked to the outer housing 110 of the injector body 100 and the piston rod member 220 is locked to the inner ram 120 of the injector body 100 when the injector head assembly 200 is in the locked position.

In this embodiment, the end cap 230 is engaged with the injector head body 210 by a first set of mating structures, the injector head body 210 is engaged with the outer housing 110 by a second set of mating structures, the injector head body 210 is engaged with the piston rod member 220 by a third set of mating structures, and the piston rod member 220 is engaged with the inner ram 120 by a fourth set of mating structures. Each mating feature set includes engagement features disposed on the two corresponding members of the mating feature set, each mating feature set being capable of limiting specific relative movement between the two corresponding members of the mating feature set. Each of the mating structure groups will be described in detail in turn.

Referring to fig. 3, the first set of mating structures includes an arm 232 located on end cap 230 and extending proximally from body 231 of end cap 230 and a first mating feature 211 (i.e., a first mating location) located on injector head body 210. The proximal inner side of the arm 232 is provided with a first protrusion 233 and the distal end of the first mating feature 211 is provided with a small step 2111. The first set of mating structures is capable of transitioning between an engaged state that axially secures the injector head body 210 and the end cap 230 together and a disengaged state that axially decouples the injector head body 210 and the end cap 230. The state shown in fig. 3 corresponds to the disengaged state of the first mating structure group, and the states shown in fig. 4 and 5 correspond to the engaged state of the first mating structure group. A direction indicator 234 is also provided on the body 231 of the end cap 230.

Specifically, the arms 232 are capable of deforming radially outward to allow the first protrusions 233 to pass over the small steps 2111 to transition the first mating structure set between the engaged and disengaged states. The first mating structure set is capable of being shifted from the engaged state to the disengaged state in response to a freehand operation by an operator when the injector head assembly 200 is not mounted to the injector body 100; when the injector head assembly 200 has been inserted into the distal end of the injector body 100 but has not reached the locked position (i.e., the process of rotating from the first transitional position to the locked position), the arms 232 are constrained by the outer housing 110 from deforming radially outward, at which point the first set of mating structures cannot be transformed from the engaged state to the disengaged state. While arms 232 are allowed to deform radially outward when injector head assembly 200 is in the locked position, a user can now actuate end cap 230 distally to disengage it from injector head body 210.

An assembled schematic view of injector head assembly 200 is shown in fig. 4 with the first set of mating structures in an engaged state, with arms 232 of end cap 230 disposed within first mating feature 211 of injector head body 210. Preferably, the injector head body 210 is provided with a circumferentially extending flange 214, the flange 214 being disposed intermittently and defining the first mating feature 211 at the discontinuity, and the proximal ends of the arms 232 and the flange 214 together defining a boss extending entirely in the circumferential direction. The circumferential boss serves to compress the elastic member 112 provided at the distal end face of the syringe body 100 to restrict movement of the syringe body 210 in the unlocking direction when the syringe body 210 is locked to the outer housing 110 and the end cap 230 has been removed. The number of the elastic members 112 is preferably two, but may be one, three or more.

Preferably, referring to fig. 5, a resilient plug 235 is mounted at a distal location on the interior of end cap 230, and the first set of mating structures is configured to allow a small axial movement between end cap 230 and injector head body 210 such that resilient plug 235 is compressed by the distal end of injector head body 210 when injector head body 210 and end cap 230 are engaged. Such an arrangement can enhance the sealing effect of the injector head assembly 200 and also ensure tight engagement between the components of the injector head assembly 200 in the assembled state.

Referring to fig. 3 to 5 and 7A, the set of mating structures between the syringe body 100 and the outer housing 110, i.e., the second set of mating structures, includes: a second protrusion 111 circumferentially intermittently disposed on the inside surface of the syringe body 100, and a second mating feature 212 (i.e., a second mating site) formed on the outside surface of the syringe body 210. The second mating feature 212 is defined by flanges 215, 214 on either axial side of the second mating feature 212, respectively, and the second set of mating structures limit relative axial movement between the injector head body 210 and the injector body 100.

During mounting of the syringe head assembly 200 to the syringe body 100, the proximal flange 215 defining the second mating feature 212 can axially pass from the discontinuity of the second protrusion 111 to bring the syringe head assembly 200 to the first transitional position, and then the syringe head assembly 200 is rotated relative to the syringe body 100 to bring the second protrusion 111 into the second mating feature 212. And, the downstream end of the second mating feature 212 in the mounting rotational direction R1 is provided with an axially extending limit projection 217 such that the limit projection 217 interferes with the second projection 111 when the injector head body 210 is rotated in the mounting rotational direction R1 to the locked position to limit continued rotation of the injector head body 210 in the mounting rotational direction R1.

Unlike the first mating structure, which is capable of changing state in response to freehand actuation by an operator, the second mating structure set is more securely engaged. If the second mating structure set is to be disengaged, it is necessary to perform the proper unloading procedure, for example, to attach the end cap 230 to the syringe body 100 and then rotate the end cap 230 and the syringe body 100 integrally in the unloading rotation direction R2. The injector head body 210 and the outer housing 110 are not separated from each other only under direct axial forces that tend to deactivate the second mating structure set. Thus, when injector head assembly 200 is mounted to the locked position, an operator can distally actuate end cap 230 to remove it without affecting the locking engagement between injector head body 210 and outer housing 110.

On the other hand, in the present embodiment, there is also a second transition position between the first transition position and the lock position. In the second transitional position, the piston rod member 220 and the inner ram 120 are lockingly engaged to disengage the injector head body 210 as the injector head body 210 continues to rotate in the mounting rotational direction R1. Correspondingly, some preferred arrangements of the engagement structures associated with the piston rod member 220 are also provided in this embodiment.

The set of mating structures between the piston rod member 220 and the injector head body 210, i.e. the third set of mating structures, is configured to limit the relative axial movement between the piston rod member 220 and the injector head body 210 and the relative rotation below a first predetermined torque, e.g. a torque acting on the piston rod member 220 or the injector head body 210 to rotate them relative to each other. The set of mating structures between the piston rod member 220 and the inner push rod 120, i.e. the fourth set of mating structures, is configured to limit the axial relative movement between the piston rod member 220 and the inner push rod 120 and the relative rotation below a second predetermined torque, e.g. a torque acting on the piston rod member 220 or the inner push rod 120 to rotate it relative to each other.

Wherein the first predetermined torque is less than the second predetermined torque. The arrangement is such that when the injector head assembly 200 is rotated in its entirety to the second transitional position, wherein the injector head body 210, the inner ram 120, and the piston rod member 220 are all in locking engagement, a force in the mounting rotational direction R1 continues to be applied to the injector head body 210, and when this force reaches a first predetermined torque, the injector head body 210 and the piston rod member 220 are rotated relative to each other, wherein the relative torque between the piston rod member 220 and the inner ram 120 has not yet reached a second predetermined torque, and the piston rod member 220 and the inner ram 120 remain engaged. That is, when the injector head assembly 200 is rotated to the second transitional position, the piston rod member 220 does not continue to rotate.

In particular, referring to fig. 3-6, the third set of mating structures includes a distally extending third protrusion 221 provided on the piston rod member 220 and a third mating feature 213 (i.e., a third mating site) provided on the injector head body 210. Distal to the mounting portion of the piston rod member 220 distal to the piston rod 220a is provided an annular extension 225, the third protrusion 221 extends distally from the extension 225, and the third protrusion 221 is flush with the radially outer surface of the extension 225. The radially inner side of the third protrusion 221 is provided with a hooking hook. The third mating feature 213 includes: the fitting groove, a click fitting portion 216 formed at a proximal end of the fitting groove, a stopper portion 218a formed on an upstream side in the fitting groove's mounting rotation direction R1, and a small projection 218 formed on a downstream side in the fitting groove's mounting rotation direction R1. The catch engagement portion 216 and the radially inner catch of the third protrusion 221 engage to limit proximal movement of the piston rod member 220 relative to the injector head body 210. The stop 218a blocks the third protrusion 221 to prevent the piston rod member 220 from rotating in the mounting rotation direction R1 with respect to the injector head body 210. The small protrusion 218 is dimensioned such that the third protrusion 221 is able to pass over the small protrusion under an action equal to or greater than the first predetermined torque, thereby disengaging the injector head body 210 and the piston rod member 220. Fig. 6 shows a state after the third protrusion 221 has passed over the small protrusion 218, when the third mating structure group has been in engagement contact.

The fourth set of mating structures includes a radially protruding fourth protrusion 222 formed on the proximal end of the piston rod member 220, and a fourth mating feature 123 (i.e., a fourth mating site, see fig. 7B) formed on the inner push rod 120. Preferably, the piston rod member 220 further comprises a cylindrical structure 223 extending proximally from the mounting base, the fourth protrusion 222 being formed at a proximal end of the cylindrical structure 223. The tubular structure 223 is provided with a plurality of axially extending slots circumferentially distributed such that the proximal end of the tubular structure 223 is slightly deformed to urge the fourth protrusion 222 into the fourth mating feature 123.

In some cases, when the injector head assembly 200 is inserted into the injector body 100, the fourth protrusion 222 may contact the inner wall of the inner push rod 120, and friction force (the magnitude of friction force is related to the interference of the fourth protrusion 222 with respect to the mating portion of the inner push rod 120) may be formed between the fourth protrusion 222 and the inner wall of the inner push rod 120 due to the existence of elastic deformation, and when the torque generated by the friction force is greater than the first predetermined torque, the piston rod member 220 cannot rotate synchronously with the inner push rod 210, such that the fourth protrusion 222 cannot reach the fourth mating feature 123, and the engagement effect of the piston rod member 220 with the inner push rod 120 is affected. To ensure the effectiveness of the fourth set of mating structures, a radially inner side of the injector head body 210 near the proximal end is provided with a first tapered protrusion 219 (i.e. a first safety protrusion) and a radially outer side of the piston rod 220a is provided with a second tapered protrusion 220c (i.e. a second safety protrusion) corresponding to the first tapered protrusion 219. The radial dimensions of both the first tapered protrusion 219 and the second tapered protrusion 220c taper distally. Only one first tapered protrusion 219 may be provided or two first tapered protrusions 219 may be provided symmetrically about the axis. Because of the provision of the first and second tapered protrusions 219, 220c, when the injector head assembly 200 is twisted toward the locked position, even if the piston rod member 220 cannot rotate synchronously with the inner ram 210, the first tapered protrusion 219 will interfere with the second tapered protrusion 220c as the injector head body 210 is twisted to a particular angle with the end cap 230 to urge the piston rod member 220 to twist until the fourth protrusion 222 reaches a position that properly engages the fourth mating feature 123.

As can be seen in connection with the above description and with reference to fig. 2, the injector head body 210 is provided with mating features of the first mating structure set (i.e., first mating feature 211), the second mating structure set (i.e., second mating feature 212), and the third mating structure set (i.e., third mating feature 213). The injector head body 210 further comprises a cavity portion 210a for receiving the piston rod 220a of the piston rod member 220 and a body mounting base 210b located proximal to the cavity portion 210 a. The first mating feature 211, the second mating feature 212, and the third mating feature 213 are all located on the body mounting base 210b. And, the second mating feature 212 is located proximal to the first mating feature 211, and the third mating feature 213 is located proximal to the second mating feature 212. The piston rod member 220 is provided with a protrusion of a third mating structure group (i.e., a third protrusion 221) formed radially inward of the hooking portion extending distally from the distal end of the mounting base, and a protrusion of a fourth mating structure group (i.e., a fourth protrusion 222), the piston rod member 220 further including a piston rod mounting base 224 and a piston rod 220a extending distally from the piston rod mounting base 224, the protrusion of the fourth mating structure group being located radially outward of the proximal end of the mounting base.

Preferably, referring back to fig. 4-6, the piston rod mounting base 224 in turn includes a pair of opposed wings 224b (the number of wings may be one, three or more in other embodiments) projecting radially outwardly, with the piston rod 220a extending distally from the mounting base. Correspondingly, a step 1211 (see fig. 7B) is formed in the outer housing 110 corresponding to the pair of wings 224B, the step 1211 being capable of abutting against the proximal side of the wings 224B to limit further proximal movement of the injector head assembly 200 at the first transition position. The step 1211 may constitute the aforementioned "limit structure". The shape of the step 1211 and the wing 224b are adapted but the circumferential dimension of the step 1211 is slightly larger than the circumferential dimension of the wing 224b to allow the piston rod member 220 to be rotatable relative to the inner push rod 120 between a first transition position and a second transition position.

Specifically, the step 1211 is discontinuous in the circumferential direction, in this embodiment, two sectors spaced apart in the circumferential direction, and at least two portions formed in other shapes spaced apart in the circumferential direction may be provided in other embodiments. The structure defined at both ends in the circumferential direction of the step 1211 is a circumference Xiang Kuai 1212 (see fig. 7B), the circumferential block 1212 protrudes radially inward with respect to the step 1211, and the circumference Xiang Kuai 1212 is capable of pushing the wing plate 224B in the rotational direction, thereby functioning as a safety in two cases:

1. As injector head assembly 200 rotates in mounting rotational direction R1: if, during rotation of the injector head body 210 from the second transitional position toward the locked position, the piston rod member 220 is accidentally not disengaged from the injector head body 210 but instead tends to continue to rotate with the injector head body 210 (i.e., tends to disengage from the inner push rod 120), the circumferential block 1212 may act as a stop for the wing 224b, preventing continued rotation of the piston rod member 220 to ensure that the piston rod member 220 is able to remain properly engaged with the inner push rod 120;

2. as injector head assembly 200 rotates in unlocking rotation direction R2: during rotation of injector head body 210 from the locked position to the second transitional position, if third protrusion 221 accidentally fails to clear tab 218 and thereby fail to enter third mating feature 213, it may result in piston rod member 220 not being integral with injector head body 210, end cap 230 and thus possibly not being removable from injector body 100 with injector head body 210, end cap 230, in which case circumferential block 1212 may also act as a push on wing 224b, pushing piston rod member 220 and injector head body 210 into proper engagement, thereby ensuring that injector head assembly 200 is removed as a whole.

It will be appreciated in connection with the foregoing that the syringe body 100 also has some preferred arrangements. For example, turning back to fig. 2, an elastic member 112 formed as an elastic column is provided on the distal end face of the outer case 110, the elastic member 112 slightly protruding from the distal end face. A second protrusion 111 is provided on the radially inner side of the outer housing 110 near the distal end, the second protrusion 111 constituting part of the second mating structure set. The second protrusion 111 is circumferentially discontinuous to allow a proximal flange of the injector head assembly 200 defining the second mating feature 212 to pass axially through the discontinuity of the second protrusion 111. The inner push rod 120 is provided with a fourth mating feature 123 near its distal end, the fourth mating feature 123 forming part of a fourth mating structure set.

Preferably, the inner push rod 120 includes an axially extending push rod body 122 and an annular mounting portion 121 at a distal end of the push rod body, the radial dimension of the annular mounting portion 121 being greater than the radial dimension of the push rod body 122. The inner push rod 120 can be used to house a drug vial, and the outer housing 110 and the inner push rod 120 are provided with a visual window for an operator to view the drug vial in an axially aligned position with the drug vial. The viewing window is configured as a plurality of hollowed-out portions 124 formed on the inner push rod 120 to be spaced apart in the circumferential direction and a plurality of transparent portions 113 formed on the outer housing 110. Each of the hollowed-out portions 124 is formed in an elongated shape extending in the axial direction; the positions of the transparent portions 113 and the hollowed portions 124 are in one-to-one correspondence.

Also preferably, the inner surface of the outer housing 110 is provided with anti-rotation protrusions (not visible from the perspective of the drawing) extending in the axial direction, and the other one of the outer surfaces of the inner push rod 120 is provided with keyways 125 corresponding to the anti-rotation protrusions, the anti-rotation protrusions and the keyways 125 cooperating to prevent relative rotation between the outer housing 110 and the inner push rod 120 but allowing relative axial movement between the outer housing 110 and the inner push rod 120.

Fig. 7A-15B illustrate the use of the syringe 1 according to the preferred embodiment of the present invention. Wherein fig. 7A, 8A, 9a … … a show the external structure of the syringe body 100 and the syringe head assembly 200 at various stages, and fig. 7B, 8B, 9B … … a 15B and fig. 7A, 8A, 9a … … a are one-to-one correspondence, the external housing 110 is omitted in fig. 7B, 8B, 9B … … a 15B to clearly show the internal push rod 120.

The corresponding structure of the syringe head assembly 200, the syringe body 100 and the syringe 1 will be described in detail below with reference to fig. 7A to 15B, in accordance with the chronological order of the use process of the syringe 1.

Referring first to fig. 7A and 7B, the syringe head assembly 200 is first mounted to the syringe body 100 prior to use. In particular, the injector head assembly 200 is insertable in a proximal direction to a first transitional position relative to the injector body 100 when oriented at a predetermined angle relative to the injector body 100, at which point a proximal flange 214 of the injector head assembly 200 defining the second mating feature 212 is able to pass from the discontinuity of the second protrusion 111 of the injector body 100. If the injector head assembly 200 is oriented at the wrong angle relative to the injector body 100, the proximal flange 214 of the injector head assembly 200 defining the second mating feature 212 will be blocked by the second protrusion 111 such that the injector head assembly 200 cannot be inserted into the first transition position.

During proximal actuation of the syringe head assembly 200 to the first transitional position relative to the syringe body 100, the circumferential ledge formed by the arms 232 of the end cap 230 and the flange 214 on the syringe head body 210 defining the first mating feature 211 press against the resilient member 112 on the distal face of the outer housing 110 such that the outer surface of the resilient member 112 is pressed flush with the distal face of the outer housing 110. The circumferential boss is a boss protruding radially outward and continuous in the circumferential direction. The proximal ends of arms 232 constitute a first boss portion and flange 214 constitutes a second boss portion. Since the circumferential ledge is a continuous ledge in the circumferential direction, the resilient member 112 will continuously remain compressed during subsequent rotation from the first transitional position to the locked position, thereby not causing resistance to rotation of the injector head assembly 200.

Preferably, when the injector head assembly 200 is in the locked position, the elastic member 112 is located at the most upstream end of the first boss portion in the mounting rotation direction R1, i.e., the elastic member 112 is located at the most upstream end of the second boss portion in the unloading rotation direction R2.

Also preferably, a groove for accommodating the elastic member 112 and having an axial depth smaller than the length of the elastic member 112 may be provided on the front end surface of the syringe body 100, allowing the elastic member 112 to be taken out of the groove. For example, in fig. 8A, 9A, 10A, 12A, 13A, and 14A, a groove 112A accommodating the elastic member 112 is shown. The elastic member 112 has good elasticity and can be removed from the syringe body 100, and such an arrangement can be achieved: if there is a substantial loss of end cap 230, the user may press on resilient member 112 by himself to unlock injector head body 210; or the user may directly remove the elastic member 112 from the syringe body 100 to unlock the syringe body 210.

With respect to the arrangement of the circumferential boss and the elastic member, there may be some other variations than those mentioned in the present embodiment. For example, the circumferential ledge defined by the end cap and the injector head body together need not be continuous in the circumferential direction, as long as the circumferential length of the circumferential ledge enables the resilient member to be continuously compressed by the circumferential ledge during rotation of the injector head assembly from the first transition position to the second transition position. As another example, the number of arms (i.e., the number of first boss portions), the number of flanges (i.e., the number of second boss portions) of the end cap may be three or more, the end cap may define at least two first boss portions, the injector head body may define at least two second boss portions, the first boss portions and the second boss portions may be alternately arranged in the circumferential direction, and the number of elastic members may be the same as the number of first boss portions, the elastic members and the first boss portions being arranged in one-to-one correspondence in the circumferential position. Also, in this embodiment, the first set of mating structures is provided at the spacing of the arms and flanges, but in other embodiments not shown, the arms and flanges may be provided solely for compressing the resilient member, and the engagement member between the end cap and the injector head body may be provided elsewhere. The first boss portion and the second boss portion may have other arrangements besides the arms, flanges.

Fig. 8A and 8B illustrate the injector head assembly 200 in a first transitional position relative to the injector body 100. At this point the syringe head assembly 200 cannot continue to move proximally relative to the syringe body 100, but can move distally to separate from the syringe body 100. At this time, the state of non-engagement is established between the injector head body 210 and the outer housing 110, and between the piston rod member 220 and the inner plunger 120. For contrast with the fourth protrusion 222 of the piston rod member 220, the portion at the proximal end of the piston rod member 220 other than the fourth protrusion 222 is denoted as 222a.

Subsequently, injector head assembly 200 is actuated in mounting rotational direction R1 to rotate to the second transitional position shown in fig. 9A and 9B. In the second transitional position, the piston rod member 220 and the inner push rod 120 are locked by the fourth set of mating structures. Specifically, a radially protruding fourth protrusion 222 formed at the proximal end of the piston rod member 220 is engaged with a fourth mating feature 123 on the inner push rod 120.

Subsequently, the injector head assembly 200 is continuously actuated to rotate from the second transitional position to the locked position. During this process, the piston rod member 220 and the injector head body 210 are disengaged, and the piston rod member 220 remains engaged with the inner ram 120, so that only the injector head body 210 and the end cap 230 continue to rotate. To achieve this arrangement, a third set of cooperating structures between the piston rod member 220 and the injector head body 210 limit relative rotation between the piston rod member 220 and the injector head body 210 below a first predetermined torque; the fourth set of mating structures between the piston rod member 220 and the inner push rod 120 limits relative rotation between the piston rod member 220 and the inner push rod 120 below the second predetermined torque. The first predetermined torque is less than the second predetermined torque. When the injector head assembly 200 is rotated in its entirety to the second transitional position, at which time the injector head body 210, the inner ram 120, and the piston rod member 220 are all in locking engagement, the injector head body 210 continues to be subjected to a force in the mounting rotational direction R1, and when this force reaches a first predetermined torque, the injector head body 210 and the piston rod member 220 are rotated relative to each other, at which time the relative torque between the piston rod member 220 and the inner ram 120 has not yet reached a second predetermined torque, so that engagement between the piston rod member 220 and the inner ram 120 is maintained. That is, when the injector head assembly 200 is rotated to the second transitional position, the piston rod member 220 does not continue to rotate.

During rotation of injector head assembly 200 from the first transitional position to the locked position, end cap 230 cannot be disengaged from injector head body 210 and the first set of mating structures between end cap 230 and injector head body 210 cannot be shifted from the engaged state to the disengaged state. This is because the arms 232 of the end cap 230 need to deform radially outwardly to disengage from the first mating features 211 on the injector head body 210, whereas the arms 232 of the end cap 230 are constrained from deforming by the outer housing 110 during rotation of the injector head assembly 200 from the first transitional position to the locked position, i.e., the radial dimension of the outer housing 110 is set to provide no room for deformation of the arms 232 of the end cap 230. When injector head assembly 200 is rotated to the locked position, a gap exists between the inner surface of outer housing 110 and arms 232 that are radially aligned with arms 232 to allow arms 232 to deform, allowing end cap 230 to be removed.

The injector head assembly 200 in the locked position is shown in fig. 10A and 10B. At this time, the end cap 230, rather than the syringe body, is pressed against the distal face of the resilient member 112 so that the resilient member 112 can resume its shape after the end cap 230 is removed.

Before end cap 230 is removed, a drug delivery operation is required. In particular, the inner ram 120 carries the piston rod member 220 proximally, which can be easily accomplished because the piston rod member 220 has been engaged with the inner ram 120 and disengaged from the injector head body 210. The plunger rod assembly 220 is moved proximally relative to the injector head body 210 such that a vacuum is created within the injector head body 210 and medical fluid is received from a drug storage vial (not shown) within the inner plunger 120 along a medical fluid passageway on the plunger rod 220a into the injector head body 210.

After the drug delivery is completed and prior to the injection step, end cap 230 is removed. Fig. 11A and 11B show a schematic view of the syringe 1 with the end cap 230 removed. It should be noted again that the first set of mating structures between end cap 230 and injector head body 210 can be shifted from an engaged state to a disengaged state in response to freehand actuation by an operator, while the second set of mating structures is relatively secure. If the engagement of the second mating structure set is to be released, it is necessary to rotate the end cap 230 and the syringe body 100 integrally in the unloading rotation direction R2. The injector head body 210 and the outer housing 110 are not separated from each other only under direct axial forces that tend to deactivate the second mating structure set. Thus, when injector head assembly 200 is mounted to the locked position, an operator can distally actuate end cap 230 to remove it without affecting the locking engagement between injector head body 210 and outer housing 110.

After end cap 230 is removed, elastic member 112 compressed by end cap 230 resumes its shape to constitute resistance to rotation of injector head body 210 in unloading rotational direction R2. Thus, with end cap 230 removed, injector head body 210 cannot be rotated from the locked position back to the first transitional position. If it is desired to remove the injector head body 210, the end cap 230 may be reinstalled into engagement with the injector head body 210.

During the injection step, the inner ram 120 is actuated, either electrically, pneumatically, or by mechanical energy provided by a spring, to move it distally relative to the outer housing 110. The piston rod member 220 compresses the medicine liquid in the syringe body 210 distally by the driving of the inner push rod 120 so that the medicine liquid is ejected outwardly from the injection micro-holes. During inhalation and injection, the outer housing 110 and the injector head body 210 are stably engaged by the second mating structure set; the piston rod member 220 and the inner push rod 120 are stably engaged by the fourth mating structure group.

After injection is completed, the injector head assembly 200 may be removed from the injector body 100. Referring to fig. 12A and 12B, end cap 230 needs to be first reinstalled proximally to syringe body 100 such that the first set of mating structures transitions from the disengaged state to the engaged state. Arms 232 of end cap 230 depress resilient member 112 thereby releasing resilient member 112 from the rotational direction of injector head body 210.

Subsequently, referring to fig. 13A and 13B, the injector head assembly 200 is rotated in the unloading rotation direction R2. In this process, referring to fig. 13B, the small protrusion on the third mating feature 213 on the injector head body 210 first actuates the third protrusion 221, bringing the third protrusion 221 into disengagement with the inner plunger 120. However, in other embodiments not shown, the engagement between the piston rod member 220 and the inner ram 120 may be unaffected only when the small protrusion and the third protrusion 221 are in contact, and the stop 218a on the third mating feature 213 and the third protrusion 221 start to actuate the third protrusion 221 when the injector head body 210 continues to rotate relative to the piston rod member 220 in the unloading rotational direction R2, at which point the contact lock between the piston rod member 220 and the inner ram 120 is enabled, the piston rod member 220 being rotatable with the injector head body 210.

Fig. 14A and 14B illustrate the injector head assembly 200 continuing to rotate in the unloading rotational direction R2 to the first transitional position. At this time, the second set of mating structures between the injector head body 210 and the outer housing 110 has been in a disengaged state, and the fourth set of mating structures between the piston rod member 220 and the inner plunger 120 has also been in a contact engaged state. The first set of mating structures between end cap 230 and injector head body 210 is in an engaged state and the third set of mating structures between injector head body 210 and piston rod member 220 is also in an engaged state. At this point, injector head assembly 200 is permitted to move distally relative to outer housing 110.

Subsequently, referring to fig. 15A and 15B, the entire syringe head assembly 200 is moved in a distal direction relative to the syringe body 100. At this point, injector head assembly 200 is in an assembled state, the first set of mating structures between end cap 230 and injector head body 210 is in an engaged state, and arms 232 of end cap 230 are positioned within first mating features 211 of injector head body 210 defined by flange 214; a third set of mating structures between the injector head body 210 and the piston rod member 220 are also in an engaged state, with a third protrusion 221 on the piston rod member 220 located within a third mating feature 213 on the injector head body 210.

Although in the present embodiment, when the injector head assembly 200 is in the locked position, the injector head body 210 is locked to the outer housing 110 of the injector body 100 and the piston rod member 220 is locked to the inner push rod 120 of the injector body 100. In other embodiments, however, the syringe body may also include other structures, and some mounting structures may be additionally provided within the syringe body for engaging the syringe body and the piston rod member, respectively. In other embodiments, deformation of the portion of the end cap corresponding to the first set of mating structures may be limited by other components than the outer housing. In yet other embodiments, the injector head body is deformed such that the first set of mating structures is capable of transitioning between the engaged state and the disengaged state, and the injector body constrains the injector head body from deforming when the injector head assembly has been inserted into the distal end of the injector body but has not reached the locked position. Alternatively, the portions of the injector head body and the end cap corresponding to the first set of mating structures are capable of being deformed simultaneously so that the first set of mating structures is capable of being transformed between an engaged state and a disengaged state, the injector body constraining the deformation of the two prior to reaching the locked position.

The projections and the mating features in the respective mating structure groups provided in this embodiment are structures extending in the circumferential direction and intermittently provided. In other embodiments, not shown, the projections and mating features in each mating feature set may be circumferentially disposed serially, and the injector may be correspondingly adapted to allow such axially continuous projections and mating features.

The engagement structure between the end cap and the syringe body of the injector head assembly of the present invention is constrained so that they remain continuously engaged before being properly mounted in a locked position relative to the syringe body, avoiding removal of the end cap with the syringe body virtually attached to the distal end of the syringe body, and improving the safety factor of operation.

The invention also provides for a reasonable engagement between the piston rod member and the injector body, which allows the engagement between the piston rod member and the injector body to be used to unlock the engagement between the piston rod member and the injector body without manual manipulation by the user.

The syringe body of the present invention also has some preferred arrangements, for example, providing a visual window for a user to view the contents of the vial, and allowing relative axial movement between the outer housing and the inner ram while preventing relative rotation. These arrangements can improve the accuracy and convenience of operation.

The syringe body and the syringe head assembly of the present invention can be separated from each other, so that the syringe head assembly or the syringe body can be conveniently replaced. Thus, the syringe body and the syringe head assembly of the present invention can be manufactured and sold separately. The description and drawings referred to in connection with the injector head assembly in the embodiments of the present invention should be considered as pertaining to the "injector head assembly" embodiments as well as to the "injector" embodiments; the description and drawings referred to in the embodiments of the present invention in relation to the syringe body should be considered as pertaining to the "syringe body" embodiments as well as to the "syringe" embodiments.

In addition, although the embodiment of the present invention is exemplified as a needleless syringe, the structure of the present invention can also be applied to a needleless syringe.

From the foregoing, those skilled in the art will readily recognize that alternative constructions to the disclosed structure may be employed as viable alternative embodiments, and that the disclosed embodiments may be combined to create new embodiments that also fall within the scope of the appended claims.

Claims

1. A syringe assembly for use with a syringe body (100) having a distal opening and a resilient member disposed on and slightly protruding from a distal face of the syringe body, wherein the syringe assembly comprises:

the injection head comprises an injection head main body (210), wherein a cavity (210 c) with an open proximal end is arranged in the injection head main body, and a micropore which is communicated with the cavity and the outside is arranged at the distal end of the injection head main body;

an end cap (230) mounted at a distal end of the injector head body,

wherein the injector head assembly is configured to be insertable into a distal opening of the injector body and rotatable to a locked position relative to the injector body and to compress the resilient member when the injector head assembly is inserted into the distal opening, wherein the end cap compresses the resilient member when the injector head assembly is in the locked position and the resilient member springs back to block the injector head body in a rotational direction when the end cap is removed.

2. The injector head assembly of claim 1, wherein the end cap and the injector head body together define a circumferential boss projecting radially outward and circumferentially continuous, a proximal face of the circumferential boss being planar and compressible against the resilient member.

3. The injector head assembly of claim 2, wherein the end cap defines at least two first boss portions, the injector head body defines at least two second boss portions, the at least two first boss portions and the at least two second boss portions together form the circumferential boss, and the first boss portions and the second boss portions are alternately disposed in a circumferential direction.

4. A syringe assembly according to claim 3, wherein the end cap comprises an arm (232) extending proximally from the body of the end cap, the proximal end of the arm constituting the first boss portion; the injection head body is provided with a flange (214) intermittently extending in the circumferential direction constituting the second boss portion.

5. The injection head assembly of claim 4, wherein the arm is provided with a first protrusion (233) on the inside of the proximal end and the discontinuity of the flange constitutes a first mating feature, the distal end of the first mating feature being provided with a small step (2111),

6. The injector head assembly of claim 5, wherein the arm is deformable radially outward to enable the first projection to clear the small step.

7. A syringe body for use with a syringe head assembly (200) including an axially separable syringe head body (210) and an end cap (230),

and, a distal end face of the syringe body is provided with a resilient member (112) projecting slightly beyond the distal end face, the resilient member being configured to be compressible by the syringe head assembly upon insertion of the syringe head assembly into the distal opening and to be compressed by the end cap when the syringe head assembly is in the locked position; the resilient member springs back to block the injector head body in a rotational direction when the end cap is removed.

8. The syringe body according to claim 7, wherein the elastic member is configured as an elastic column extending in an axial direction, and a distal end face of the syringe body is provided with an elastic column groove for accommodating the elastic column and having an axial depth smaller than a length of the elastic column.

9. The injector body of claim 7, wherein the resilient member is compressed by a circumferential boss formed by a boss portion defined by the injector head body and a boss portion defined by the end cap, and is positioned to: the elastic member is located at an uppermost stream end of a boss portion defined by the end cap in a mounting rotation direction when the injection head assembly is located at the lock position.

10. The syringe body according to claim 7, wherein the number of the elastic members is at least two, and at least two of the elastic members are uniformly arranged in the circumferential direction.

11. A syringe, wherein the syringe (1) comprises:

a syringe body (100) having a distal opening and having a resilient member located on a distal face of the syringe body that protrudes slightly beyond the distal face;

A syringe assembly (200) including a syringe body and an end cap axially separable from and located on the syringe body, the syringe assembly being insertable into a distal opening of the syringe body and rotatable to a locked position relative to the syringe body,

12. The injector of claim 11, wherein the end cap and the injector head body together define a circumferential boss projecting radially outward and circumferentially continuous, a proximal face of the circumferential boss being planar and compressible against the resilient member.

13. The injector of claim 12, wherein the end cap defines at least two first boss portions, the injector head body defines at least two second boss portions, the at least two first boss portions and the at least two second boss portions together comprise the circumferential boss, and the first boss portions and the second boss portions alternate in the circumferential direction.

14. The syringe of claim 13, wherein the end cap includes an arm (232) extending proximally from a body of the end cap, a proximal end of the arm constituting the first boss portion; the injection head body is provided with a flange (214) intermittently extending in the circumferential direction constituting the second boss portion.

15. The syringe of claim 14, wherein the arm is provided with a first protrusion (233) on the inside of the proximal end and the discontinuity of the flange constitutes a first mating feature, the distal end of which is provided with a small step (2111),

16. The syringe of claim 15, wherein the arm is deformable radially outwardly to allow the first projection to clear the small step,

17. The syringe according to claim 13, wherein the number of the elastic members is at least two, and the elastic members and the first boss portions are provided in one-to-one correspondence.

18. The injector of claim 13, wherein the resilient member is located at an uppermost upstream end of the first boss portion in a mounting rotational direction when the injector head assembly is located in the locked position.