CN113945961A - Drug marking apparatus and method - Google Patents
Drug marking apparatus and method Download PDFInfo
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- CN113945961A CN113945961A CN202111226835.5A CN202111226835A CN113945961A CN 113945961 A CN113945961 A CN 113945961A CN 202111226835 A CN202111226835 A CN 202111226835A CN 113945961 A CN113945961 A CN 113945961A
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- 239000003814 drug Substances 0.000 title claims abstract description 59
- 229940079593 drug Drugs 0.000 title claims abstract description 38
- 238000000034 method Methods 0.000 title claims abstract description 13
- 239000000243 solution Substances 0.000 claims abstract description 151
- 239000000941 radioactive substance Substances 0.000 claims abstract description 89
- 230000000694 effects Effects 0.000 claims abstract description 57
- 238000002347 injection Methods 0.000 claims abstract description 31
- 239000007924 injection Substances 0.000 claims abstract description 31
- 238000001514 detection method Methods 0.000 claims abstract description 13
- GKLVYJBZJHMRIY-OUBTZVSYSA-N Technetium-99 Chemical compound [99Tc] GKLVYJBZJHMRIY-OUBTZVSYSA-N 0.000 claims description 34
- 239000000654 additive Substances 0.000 claims description 27
- 230000000996 additive effect Effects 0.000 claims description 27
- 239000011259 mixed solution Substances 0.000 claims description 25
- 230000002285 radioactive effect Effects 0.000 claims description 11
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 8
- 239000000284 extract Substances 0.000 claims description 6
- 239000011780 sodium chloride Substances 0.000 claims description 4
- 230000005855 radiation Effects 0.000 abstract description 5
- 238000002372 labelling Methods 0.000 abstract description 3
- 230000005540 biological transmission Effects 0.000 abstract description 2
- 239000002245 particle Substances 0.000 description 14
- 238000002386 leaching Methods 0.000 description 8
- 102000004169 proteins and genes Human genes 0.000 description 7
- 108090000623 proteins and genes Proteins 0.000 description 7
- 238000005406 washing Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 239000012460 protein solution Substances 0.000 description 2
- 229940121896 radiopharmaceutical Drugs 0.000 description 2
- 239000012217 radiopharmaceutical Substances 0.000 description 2
- 230000002799 radiopharmaceutical effect Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
- G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
- G01T1/16—Measuring radiation intensity
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F23/00—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
- G01F23/22—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water
- G01F23/28—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water by measuring the variations of parameters of electromagnetic or acoustic waves applied directly to the liquid or fluent solid material
- G01F23/296—Acoustic waves
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- Spectroscopy & Molecular Physics (AREA)
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Abstract
The application relates to a drug labeling apparatus and method, comprising a first container containing a first preset volume of a drug solution to be labeled, a second container containing a radioactive substance solution, an activity detection device for detecting the activity of the radioactive substance solution in the second container, a conveying device, a first injection device and a controller, wherein the activity of the radioactive substance solution decays with the passage of time; the controller is used for: determining the volume of the required radioactive substance solution according to the volume of the drug solution to be marked and the activity of the radioactive substance solution; the control transmission device transmits the first container to the target position, and controls the first injection device to extract the radioactive substance solution with the corresponding volume from the second container and inject the solution into the first container, so that the radioactive substance can completely mark the medicine to be marked in the first container, the automation of the marking process of the radioactive substance on the medicine to be marked is realized, and the radiation of the radioactive substance on human bodies is reduced.
Description
Technical Field
The present application relates to the field of drug marking technology, and more particularly, to a drug marking apparatus and method.
Background
Radioisotope-labeled protein particles are important means in modern medicine, and are mainly used for tracking protein tracks and determining protein action positions after protein is injected into organisms.
At present, the protein particles are generally labeled by radioactive isotopes in a manner of manually mixing a radioactive isotope solution and a protein solution, but radiation generated by radioactive substances can cause certain damage to human bodies.
Disclosure of Invention
In order to reduce the harm caused by radioactive substances radiating human bodies in the process of marking proteins, the application provides a medicine marking device and a method.
In a first aspect, the present application provides a drug marking device, which adopts the following technical solution:
a medication marking apparatus comprising:
the device comprises a first container, a second container, an activity detection device, a transmission device, a first injection device and a controller, wherein the first container is used for containing a first preset volume of a drug solution to be marked, the second container is used for containing a radioactive substance solution, the activity detection device is used for detecting the activity of the radioactive substance solution in the second container, and the activity of the radioactive substance solution decays along with the lapse of time;
the controller is configured to: determining the volume of the required radioactive substance solution according to the volume of the drug solution to be marked and the activity of the radioactive substance solution; and controlling the conveying device to convey the first container to the target position, and controlling the first injection device to extract the corresponding volume of radioactive substance solution from the second container and inject the solution into the first container, so that the radioactive substance can completely mark the medicine to be marked in the first container.
By adopting the technical scheme, the controller can determine the volume of the required radioactive substance solution according to the volume of the medicine to be marked, the activity of the medicine to be marked and the activity of the radioactive medicine, control the conveying device to convey the first container to the target position, control the first injection device to extract the radioactive substance solution with the corresponding volume in the second container and inject the radioactive substance solution into the first container, so that the radioactive substance can completely mark the medicine to be marked, automation of the marking process of the radioactive substance on the medicine to be marked is realized, contact between personnel and the radioactive substance is avoided, and radiation of the radioactive substance on human bodies is reduced.
Optionally, the device further comprises a third container and a second injection device, the third container and the second injection device are used for containing the additive solution, and the controller is further used for controlling the second injection device to extract the additive solution from the third container and inject the additive solution into the first container when the volume of the mixed solution in the first container does not reach a second preset volume until the volume of the mixed solution in the first container reaches the second preset volume.
By adopting the technical scheme, the volume of the mixed solution of the medicine finished by the finished product marking is certain, after the required radioactive substance solution is added into the first container, if the volume of the mixed solution does not reach the second preset volume, the additive solution with the corresponding volume needs to be supplemented into the first container through the second injection device, so that the volumes of the finished product mixed solution are both the second preset volume.
Optionally, the first injection device includes a first robot arm and a first syringe, and the controller is configured to control the first robot arm to move the first syringe to the second container and extract the corresponding volume of the radioactive substance solution, move the first syringe to the first container, and inject the radioactive substance solution into the first container.
Through adopting above-mentioned technical scheme, first arm and first syringe cooperation work, first arm plays the effect of removing first syringe for the controller can be through controlling first arm, makes first arm can remove first syringe to the second container and extract corresponding volume's radioactive substance solution, moves first syringe to first container and is about to the radioactive substance solution to pour into first container into again.
Optionally, the second injection device includes a second mechanical arm and a second syringe, and the controller is configured to control the second mechanical arm to move the second syringe to the third container and draw a corresponding volume of the additive solution, move the second syringe to the first container, and inject the additive solution into the first container.
Through adopting above-mentioned technical scheme, second arm and second syringe cooperation work, the second arm plays the effect of removing the second syringe for the controller can be through controlling the second arm, makes the second arm can remove the second syringe to the second container and extract corresponding volume's radioactive substance solution, moves the second syringe to first container again and is about to inject radioactive substance solution into first container in
Optionally, a leaching device is arranged in the second container, and radioactive substances are arranged on the leaching device.
By adopting the technical scheme, the leaching device is used for supplementing radioactive substances into the second container.
Optionally, the controller is configured to control the rinsing device to be turned on when the activity of the radioactive substance solution in the second container is lower than a preset activity.
Through adopting above-mentioned technical scheme, when the activity of the radioactive substance solution in the second container is less than predetermineeing the activity, the controller control drip washing device opens in order to supply radioactive substance in the second container, improves the activity of radioactive substance in the second container, reduces first injection device and need inject too much radioactive substance solution into first container, leads to the condition that the volume of finished product mixed solution exceeds predetermined finished product mixed solution volume.
Optionally, the controller is further configured to control the washing device to be closed when the volume of the radioactive substance in the second container is larger than a third preset volume.
By adopting the technical scheme, as the radioactive substance decays along with the lapse of time, the more the volume of the solution of the radioactive substance in the second container, the greater the loss caused by the decay, therefore, the solution of the radioactive substance in the second container is not too much, and when the volume of the solution of the radioactive substance in the second container is larger than the third preset volume, the controller controls the leaching device to be closed, so that the loss caused by the decay of the radioactive substance can be reduced to a certain extent.
Optionally, the radioactive substance solution is a technetium [99mTc ] solution, and the drug solution to be labeled is a Ma solution.
Optionally, the additive solution is a NaCl solution.
In a second aspect, the present application provides a medication marking apparatus for use as described in any of the first aspects, comprising:
detecting the activity of the radioactive substance solution in the second container, and determining the volume of the required radioactive substance solution according to the volume and the activity of the drug solution to be marked in the first container;
withdrawing a corresponding volume of radioactive solution and injecting it into a first container;
after the radioactive substance solution is injected into the first container, when the volume of the mixed solution in the first container does not reach the preset volume, the additive is extracted from the third container and injected into the first container until the volume of the mixed solution in the first container reaches the preset volume.
The utility model discloses a medicine marking device, the controller can be according to the volume of waiting to mark the medicine, wait to mark the activity of medicine and the activity of radiopharmaceutical, confirm the volume of required radioactive substance solution, and control conveyer and convey first container to the target location, then control first injection apparatus and extract corresponding volume's radioactive substance solution in the second container, and inject to first container in, make the radioactive substance can be with waiting to mark the whole marks of medicine, realize the automation of radioactive substance to waiting to mark the medicine marking process, personnel's manual radioactive substance mark has been avoided, the radiation of radioactive substance to the human body has been avoided.
Drawings
Fig. 1 is a schematic structural diagram of a system of a drug marking device according to an embodiment of the present application.
Fig. 2 is a schematic diagram of the overall structure of a medicine marking device according to an embodiment of the present application.
Fig. 3 is a cross-sectional view of a second container of a medication marking apparatus according to an embodiment of the present application.
Fig. 4 is a flow chart of a drug labeling method according to an embodiment of the present application.
Description of reference numerals: 1. a first container; 2. a second container; 3. a third container; 4. a first injection device; 41. a first robot arm; 42. a first syringe; 5. a second injection device; 51. a second mechanical arm; 52. a second syringe; 6. an activity detection device; 7. a liquid level detection device; 71. an ultrasonic transducer; 8. a conveying device; 81. a card slot; 9. a leaching device; 10. and a controller.
Detailed Description
Various exemplary embodiments of the present disclosure will be described in detail below with reference to the accompanying drawings. It should be noted that: the relative arrangement of the components and steps, the numerical expressions, and numerical values set forth in these embodiments do not limit the scope of the present disclosure unless specifically stated otherwise.
At present, the protein particles are generally labeled by radioactive isotopes in a manner of manually mixing a radioactive isotope solution and a protein solution, but radiation generated by radioactive substances can cause certain damage to human bodies.
Accordingly, there is a need for a medication marking apparatus and method.
The present application discloses a drug marking apparatus, referring to fig. 1 and 2, comprising a first container 1 containing a first preset volume V1 of a drug solution to be marked, a second container 2 containing a radiopharmaceutical solution, a third container 3 containing an additive solution, a delivery device 8, a first injection device 4, a second injection device 5, and a controller 10.
In the embodiment of the present application, the drug solution to be labeled may be a Ma solution, the radioactive substance solution may be a technetium [99mTc ] solution, and the additive solution may be a NaCl solution.
Referring to fig. 1 to 3, a first container 1 containing a solution to be labeled is placed on a conveyor 8, the first container 1 may be a medicine bottle for containing the solution, a controller 10 controls the conveyor 8 to convey the first container 1 to a target position, a second container 2 is disposed at one side of the target position, a radioactive substance is contained in the second container 2, the activity of the radioactive substance solution decays with time, in order to obtain the activity of the radioactive substance solution in real time, an activity detection device 6 for detecting the activity of the radioactive substance solution is disposed in the second container 2, the activity detection device 6 may be an activity meter, the controller 10 can determine a required volume of the radioactive substance solution according to the volume of the drug solution to be labeled and the activity of the radioactive substance solution, and then the controller 10 controls the first injection device 4 to extract a corresponding volume of the radioactive substance solution from the second container 2, injected into the first container 1, so that the radioactive substance can completely mark the drug to be marked.
In one specific example:
ma solution to be labeled: the first preset volume V1 is 1ml, the activity C1 is 3 multiplied by 108mol/L, and the Ma particle amount n1 is 3 multiplied by 105 mol;
the required technetium [99mTc ] particle size n2 is known to be equal to the Ma particle size n 1;
i.e., technetium [99mTc ] solution: n2 is 3X 105 mol;
the activity detection apparatus 6 can detect the activity C2 of the technetium [99mTc ] solution in the second container 2 in real time, and if the activity of the technetium [99mTc ] solution in the second container 2 is C2, the volume of the technetium [99mTc ] solution required is V2= n/C2, taking C2 as 1.5 × 108mol/L as an example,
V2= n2/ C2=（3×105）/（1.5×108）=2×10-3L=2ml；
the controller 10 can control the first injection device 4 to withdraw a volume of 2ml of technetium [99mTc ] solution in the second container 2 and inject it into the first container 1 so that the technetium [99mTc ] particles can fully label the Ma particles. It should be noted that since the activity of the technetium [99mTc ] solution is changed in real time, the volume of the technetium [99mTc ] solution required for each injection is also changed in real time.
In the embodiment of the present application, the first injection device 4 includes a first robot 41 and a first syringe 42, the first syringe 42 is disposed at the end of the first robot 41, and the controller 10 can control the first robot 41 such that the first robot 41 moves the first syringe 42 to the second container 2 and extracts a corresponding volume of technetium [99mTc ] solution, then moves the first syringe 42 to the first container 1, and injects the technetium [99mTc ] solution into the first container 1.
Since there is a strict standard for the volume of the labeled drug at the time of production, and the volume of the finished mixed solution is the second preset volume V3, after mixing the technetium [99mTc ] solution with the Ma solution, if the volume of the mixed solution does not reach the second preset volume V3, it is necessary to inject an additive into the first container 1 so that the volume of the mixed solution in the first container 1 reaches the second preset volume V3. Therefore, at a position opposite to the second container 2 on the other side of the transfer device 8, a third container 3 is provided, the third container 3 containing the additive solution therein, and the controller 10 is configured to control the second injection device 5 to draw a corresponding volume of the additive solution in the third container 3 and inject the additive solution into the first container 1 such that the volume of the mixed solution in the first container 1 reaches the second preset volume V3 when the volume of the mixed solution in the first container 1 does not reach the second preset volume V3 after the technetium [99mTc ] solution is injected into the first container 1.
In one specific example:
finished product mixed solution: volume V3 (second preset volume) was 4 ml;
ma solution to be labeled: the first preset volume V1 is 1ml, the activity C1 is 3 multiplied by 108mol/L, and the Ma particle amount n1 is 3 multiplied by 105 mol;
technetium [99mTc ] solution: activity C2 is 1.5 × 108mol/L, the required technetium [99mTc ] particle size n2 is equal to Ma particle size n1, n2 is 3 × 105 mol;
V2= n2/ C2=（3×105）/（1.5×108）=2×10-3L=2ml；
after the first injection device 4 injected the technetium [99mTc ] solution of volume V2 into the first container 1, it was known that the Ma solution of first preset volume V1 was previously placed in the first container 1, and therefore, V4=4-1-2=1ml since the required volume of the additive solution V4= V3-V1-V2. The controller 10 controls the second injection device 5 to draw 1ml of the additive solution in the second container 2 and then inject the additive solution into the first container 1 so that the volume of the mixed solution in the first container 1 can reach a second preset volume V3.
The second injection device 5 includes a second robot arm 51 and a second syringe 52, the second syringe 52 is disposed at an end of the second robot arm 51, and the controller 10 can control the second robot arm 51 such that the second robot arm 51 moves the second syringe 52 to the third container 3 and draws a corresponding volume V4 of the additive solution to inject into the first container 1.
Since the activity C2 of the technetium [99mTc ] solution in the second container 2 decays with time, when the activity C2 of the technetium [99mTc ] solution in the second container 2 is too low, the volume V2 of the technetium [99mTc ] solution required for completely labeling the Ma particles in the first container 1 increases, therefore, the second container 2 is further provided with the leaching apparatus 9, the leaching apparatus 9 is provided with the radioactive substance, and when the activity of the radioactive substance solution in the second container 2 is lower than the first predetermined activity C3, the controller 10 controls the leaching to be opened to flush the radioactive plasmid particles into the second container 2, so as to increase the activity of the radioactive substance solution.
In the embodiment of the present application, taking the radioactive substance as technetium [99mTc ] as an example, the second preset volume V3 of the finished mixed solution is 4ml, the volume of the Ma solution to be labeled is 1ml, and in order to ensure that the second preset volume V3 of the mixed solution does not exceed 4ml after the technetium [99mTc ] solution is added into the first container 1, the volume V2 of the technetium [99mTc ] solution may be 3ml at maximum, the first preset activity C3= n2/(3 × 10-3) =3 × 105/(3 × 10-3) =108mol/L of the technetium [99mTc ] solution is known, and when the activity detection device 6 detects that the activity C2 of the technetium [99mTc ] solution in the second container 2 is lower than 108mol/L, the controller 10 controls the elution device 9 to start to increase the activity C2 of the technetium [99mTc ] solution in the second container 2.
Since the activity C2 of the technetium [99mTc ] solution decreases with time, the larger the volume of the technetium [99mTc ] solution in the second container 2, the more the technetium [99mTc ] particles decay with time, and the greater the corresponding loss, therefore, when the volume of the technetium [99mTc ] solution in the second container 2 reaches the third preset volume V5, the controller 10 controls the washing apparatus 9 to be closed, and the third preset volume V5 may be 10ml, 15ml, or other volumes, depending on the specific situation.
The volume of technetium 99mTc solution in the second container 2 may be detected by providing a level detection device 7 in the second container 2, the level detection device 7 being used to detect the level of the radioactive solution in the second container 2, the level detection device 7 being a level detector, in particular an ultrasonic level meter, having two ultrasonic transducers 71, one 71 being provided at the bottom of the second container 2 and the other 71 being provided at the top of the second container 2, the two ultrasonic transducers 71 being able to alternately act as an ultrasonic transmitter and an ultrasonic receiver. The ultrasonic level meter detects the volume of the radioactive substance solution in the second container 2 and outputs the volume to the controller 10.
In this embodiment, the transferring device 8 may include a conveyor belt provided with slots 81 matched with the first containers 1, each first container 1 is placed in one of the slots 81, the controller 10 controls the conveyor belt to transfer one of the first containers 1 to the target position, and stops for a predetermined time after the first injecting device 4 injects the technetium [99mTc ] solution into the first container 1 and the second injecting device 5 injects the NaCl solution into the first container 1, and then transfers the next first container 1 to the target position. The first container 1 containing the marked mixed solution may be transferred to the next process by a conveyor belt, and the first container 1 may be sealed, packaged, and the like.
The present application also discloses a medicine marking method applied to the above medicine marking apparatus, as shown in fig. 4, including:
step S101, detecting the activity of the radioactive substance solution in the second container 2, and determining the volume of the required radioactive substance solution according to the volume and the activity of the drug solution to be labeled in the first container 1;
step S102, extracting a corresponding volume of radioactive solution and injecting the radioactive solution into the first container 1;
step S103, after the radioactive substance solution is injected into the first container 1, when the volume of the mixed solution in the first container 1 does not reach the preset volume, extracting the additive from the third container 3 and injecting the additive into the first container 1 until the volume of the mixed solution in the first container 1 reaches the second preset volume.
The above embodiments are preferred embodiments of the present application, and the protection scope of the present application is not limited by the above embodiments, so: all equivalent changes made according to the structure, shape and principle of the present application shall be covered by the protection scope of the present application.
Claims (10)
1. A medication marking apparatus, comprising:
the device comprises a first container (1) containing a first preset volume of a drug solution to be marked, a second container (2) containing a radioactive substance solution, an activity detection device (6) for detecting the activity of the radioactive substance solution in the second container (2), a conveying device (8), a first injection device (4) and a controller (10), wherein the activity of the radioactive substance solution decays along with the lapse of time;
the controller (10) is configured to: determining the volume of the required radioactive substance solution according to the volume of the drug solution to be marked and the activity of the radioactive substance solution; controlling the conveying device (8) to convey the first container (1) to a target position, and controlling the first injection device (4) to extract a corresponding volume of radioactive substance solution from the second container (2) and inject the solution into the first container (1), so that the radioactive substance can completely mark the medicine to be marked in the first container (1).
2. The medication marking apparatus according to claim 1, further comprising a third container (3) for holding an additive solution and a second injection device (5), wherein the controller (10) is further configured to control the second injection device (5) to draw the additive solution from the third container (3) and inject the additive solution into the first container (1) until the volume of the mixed solution in the first container (1) reaches a second preset volume when the volume of the mixed solution in the first container (1) does not reach the second preset volume.
3. A medication marking apparatus according to claim 2, wherein said first injection device (4) comprises a first robot arm (41) and a first syringe (42), said controller (10) being adapted to control the first robot arm (41) such that the first robot arm (41) moves the first syringe (42) to the second container (2) and extracts the corresponding volume of the solution of the radioactive substance, moves the first syringe (42) to the first container (1) and injects the solution of the radioactive substance into the first container (1).
4. A medication marking apparatus according to claim 2, wherein the second injection device (5) comprises a second mechanical arm (51) and a second syringe (52), the controller (10) being configured to control the second mechanical arm (51) such that the second mechanical arm (51) moves the second syringe (52) to the third receptacle (3) and draws a corresponding volume of the additive solution, moves the second syringe (52) to the first receptacle (1) and injects the additive solution into the first receptacle (1).
5. A medication marking apparatus according to any of claims 1 to 4, characterized in that a rinsing device (9) is arranged in said second container (2), said rinsing device (9) being provided with a radioactive substance.
6. Pharmaceutical marking apparatus according to claim 5, characterized in that the controller (10) is adapted to control the rinsing device (9) to be switched on when the activity of the solution of radioactive substance in the second container (2) is lower than a first predetermined activity.
7. Pharmaceutical marking apparatus according to claim 6, wherein the controller (10) is further adapted to control the rinsing device (9) to be closed when the volume of radioactive substance in the second container (2) is larger than a third predetermined volume.
8. The drug marking apparatus according to claim 1, wherein the radioactive substance solution is a technetium [99mTc ] solution, and the drug solution to be marked is a Ma solution.
9. The drug marking apparatus of claim 2, wherein the additive solution is a NaCl solution.
10. A drug marking method applied to the drug marking apparatus according to any one of claims 2 to 4, comprising:
detecting the activity of the radioactive substance solution in the second container (2), and determining the volume of the required radioactive substance solution according to the volume and the activity of the drug solution to be marked in the first container (1);
drawing a corresponding volume of radioactive solution and injecting it into the first container (1);
after the radioactive substance solution is injected into the first container (1), when the volume of the mixed solution in the first container (1) does not reach the preset volume, the additive is extracted from the third container (3) and injected into the first container (1) until the volume of the mixed solution in the first container (1) reaches the preset volume.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114796719A (en) * | 2022-06-29 | 2022-07-29 | 山东大华医特环保工程有限公司 | Automatic partial shipment system of radiopharmaceutical |
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